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Search of human proteins with 187936949
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187936949 solute carrier family 39 (zinc transporter),
member 10 [Homo sapiens]
(831 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187936949 solute carrier family 39 (zinc transporter), member... 1751 0.0
gi|55741750 solute carrier family 39 (zinc transporter), member ... 1751 0.0
gi|153252201 solute carrier family 39 (zinc transporter), member... 483 e-136
gi|153252214 solute carrier family 39 (zinc transporter), member... 376 e-104
gi|206597541 solute carrier family 39 (metal ion transporter), m... 235 1e-61
gi|206597539 solute carrier family 39 (metal ion transporter), m... 235 1e-61
gi|205830424 solute carrier family 39 (zinc transporter), member... 219 6e-57
gi|190360568 solute carrier family 39 (zinc transporter), member... 219 6e-57
gi|190358541 solute carrier family 39 (zinc transporter), member... 218 2e-56
gi|205830426 solute carrier family 39 (zinc transporter), member... 188 2e-47
gi|223633939 solute carrier family 39 (zinc transporter), member... 161 2e-39
gi|223633937 solute carrier family 39 (zinc transporter), member... 161 2e-39
gi|115430259 solute carrier family 39 (zinc transporter), member... 161 3e-39
gi|115430255 solute carrier family 39 (zinc transporter), member... 161 3e-39
gi|24586665 solute carrier family 39 (zinc transporter), member ... 150 6e-36
gi|205830407 solute carrier family 39 (zinc transporter), member... 150 6e-36
gi|205830403 solute carrier family 39 (zinc transporter), member... 150 6e-36
gi|205830405 solute carrier family 39 (zinc transporter), member... 136 7e-32
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 112 1e-24
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 112 1e-24
gi|40255101 solute carrier family 39 (zinc transporter), member ... 87 8e-17
gi|190014617 solute carrier family 39 (zinc transporter), member... 83 9e-16
gi|40254928 solute carrier family 39 (zinc transporter), member ... 60 1e-08
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 48 4e-05
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 48 4e-05
gi|4504487 histidine rich calcium binding protein precursor [Hom... 46 2e-04
gi|156415986 solute carrier family 39 (zinc transporter), member... 44 5e-04
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 44 8e-04
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens] 43 0.001
gi|21314720 Smad nuclear interacting protein [Homo sapiens] 42 0.002
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 1751 bits (4534), Expect = 0.0
Identities = 831/831 (100%), Positives = 831/831 (100%)
Query: 1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 60
MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK
Sbjct: 1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 60
Query: 61 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 120
KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG
Sbjct: 61 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 120
Query: 121 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 180
KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH
Sbjct: 121 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 180
Query: 181 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 240
HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS
Sbjct: 181 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 240
Query: 241 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 300
NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD
Sbjct: 241 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 300
Query: 301 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 360
NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF
Sbjct: 301 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 360
Query: 361 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 420
TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL
Sbjct: 361 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 420
Query: 421 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 480
SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS
Sbjct: 421 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 480
Query: 481 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 540
HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST
Sbjct: 481 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 540
Query: 541 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 600
IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE
Sbjct: 541 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 600
Query: 601 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 660
EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD
Sbjct: 601 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 660
Query: 661 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 720
LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV
Sbjct: 661 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 720
Query: 721 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 780
LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML
Sbjct: 721 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 780
Query: 781 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF 831
PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF
Sbjct: 781 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF 831
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 1751 bits (4534), Expect = 0.0
Identities = 831/831 (100%), Positives = 831/831 (100%)
Query: 1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 60
MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK
Sbjct: 1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 60
Query: 61 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 120
KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG
Sbjct: 61 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 120
Query: 121 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 180
KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH
Sbjct: 121 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 180
Query: 181 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 240
HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS
Sbjct: 181 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 240
Query: 241 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 300
NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD
Sbjct: 241 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 300
Query: 301 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 360
NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF
Sbjct: 301 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 360
Query: 361 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 420
TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL
Sbjct: 361 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 420
Query: 421 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 480
SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS
Sbjct: 421 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 480
Query: 481 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 540
HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST
Sbjct: 481 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 540
Query: 541 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 600
IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE
Sbjct: 541 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 600
Query: 601 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 660
EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD
Sbjct: 601 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 660
Query: 661 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 720
LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV
Sbjct: 661 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 720
Query: 721 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 780
LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML
Sbjct: 721 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 780
Query: 781 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF 831
PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF
Sbjct: 781 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF 831
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 483 bits (1242), Expect = e-136
Identities = 306/854 (35%), Positives = 447/854 (52%), Gaps = 126/854 (14%)
Query: 5 MHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEKKYYI 64
M K +I +LTF N HE A + ++ S + A + ++Y++
Sbjct: 1 MARKLSVILILTFALSVTNPLHELK---AAAFPQTTEKISPNWESGINVDLAISTRQYHL 57
Query: 65 EKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEGKHFH 124
++LF RYGEN LS G KLL N+G+ + K + I+H+ HDH H D H
Sbjct: 58 QQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHD---HDH--HSD----------H 102
Query: 125 SHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRHHHRL 184
H+ H + SD +H DH H H H
Sbjct: 103 EHHSDHERH--------------------------------SDHEHHSDHEHHSDHDHHS 130
Query: 185 HHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKSNENS 244
HH+ H + ++ P + S + + + P+ ++ K + ++
Sbjct: 131 HHN--HAASGKNKRKALCPDHDSDSSGKDP----RNSQGKGAHRPEHASGRRNVKDSVSA 184
Query: 245 EVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPDNEGE 304
+T +G H + + P + + + P P +
Sbjct: 185 SEVTSTVYNTVSEG-------THFLETIETPRPGKLFPKDVSSSTP--------PSVTSK 229
Query: 305 LRHTRKREAPHVKNNAIISLRKDL----NEDDHHHECLNVTQLLKYYGHGANSPISTDLF 360
R +R A N ++ RK N +++ EC N ++LL +G G P++ F
Sbjct: 230 SRVSRL--AGRKTNESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEF 287
Query: 361 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 420
YLCPA++ QID+R C+ H + E K +L AW+ G I+I++IS L
Sbjct: 288 NYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSL---------QIAWVGGFIAISIISFL 338
Query: 421 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHG---- 476
SLLGVILVP++N+ FKFLL+FLVALAVGT+SGDA LHLLPHS H HSH H
Sbjct: 339 SLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEM 398
Query: 477 -HGHSHGHESNKFLEE---YDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFM 532
G H S++ +EE +D+ KGL ALGG+Y +F++EH + + K +K ++ K +
Sbjct: 399 KRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQK-K 457
Query: 533 KQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESP 592
+N ++ I ++LS ++ + + + + TDD R + E + + QQ +
Sbjct: 458 PENDDDVEIKKQLSKYESQLSTNEEKVD------TDDRTEGYLRADSQEPSHFDSQQPA- 510
Query: 593 PKNYLCIEEEKIIDHSHSDGLHTIH-----EHDLHAAAHN----------HHGENKTVLR 637
+ EEE +I H+H ++ + ++ H+ H+ HH + +L
Sbjct: 511 ----VLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILH 566
Query: 638 KHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLT 697
H+HQ HH HSH +S +LK+ G+A +AWMVIMGDG+HNFSDGLAIGAAF+ GL+
Sbjct: 567 HHHHQNHHPHSHSQR---YSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLS 623
Query: 698 GGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYAN 757
G+STS+AVFCHELPHELGDFAVLLKAGMTVKQA++YN LSAM+AY+GM G +G YA
Sbjct: 624 SGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAE 683
Query: 758 NITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLV 817
N+++WIFA+TAG+F+YVALVDM+PEMLH D +HG G F LQN G+L GF IML+
Sbjct: 684 NVSMWIFALTAGLFMYVALVDMVPEMLHNDA--SDHGCSRWGYFFLQNAGMLLGFGIMLL 741
Query: 818 IALYEDKIVFDIQF 831
I+++E KIVF I F
Sbjct: 742 ISIFEHKIVFRINF 755
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 376 bits (965), Expect = e-104
Identities = 205/454 (45%), Positives = 287/454 (63%), Gaps = 47/454 (10%)
Query: 350 GANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWIC 409
G P++ F YLCPA++ QID+R C+ H + E K +L AW+
Sbjct: 2 GIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSL---------QIAWVG 52
Query: 410 GIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDH 469
G I+I++IS LSLLGVILVP++N+ FKFLL+FLVALAVGT+SGDA LHLLPHS H H
Sbjct: 53 GFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHH 112
Query: 470 SHQHAHG-----HGHSHGHESNKFLEE---YDAVLKGLVALGGIYLLFIIEHCIRMFKHY 521
SH H G H S++ +EE +D+ KGL ALGG+Y +F++EH + + K +
Sbjct: 113 SHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQF 172
Query: 522 KQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETE 581
K ++ K + +N ++ I ++LS ++ + + + + TDD R + E
Sbjct: 173 KDKKKKNQK-KPENDDDVEIKKQLSKYESQLSTNEEKVD------TDDRTEGYLRADSQE 225
Query: 582 LTDLEGQQESPPKNYLCIEEEKIIDHSHSDGLHTIH-----EHDLHAAAHN--------- 627
+ + QQ + + EEE +I H+H ++ + ++ H+ H+
Sbjct: 226 PSHFDSQQPA-----VLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLI 280
Query: 628 -HHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGL 686
HH + +L H+HQ HH HSH +S +LK+ G+A +AWMVIMGDG+HNFSDGL
Sbjct: 281 HHHHDYHHILHHHHHQNHHPHSHSQR---YSREELKDAGVATLAWMVIMGDGLHNFSDGL 337
Query: 687 AIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGM 746
AIGAAF+ GL+ G+STS+AVFCHELPHELGDFAVLLKAGMTVKQA++YN LSAM+AY+GM
Sbjct: 338 AIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGM 397
Query: 747 LIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 780
G +G YA N+++WIFA+TAG+F+YVALVDM+
Sbjct: 398 ATGIFIGHYAENVSMWIFALTAGLFMYVALVDMV 431
Score = 34.7 bits (78), Expect = 0.37
Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 3/39 (7%)
Query: 165 KSDD--KHMHDHNHRLRHHHRLHHHLDHNNTHHFHNDSI 201
+SDD H HD++H L HHH +HH H+++ + + +
Sbjct: 275 QSDDLIHHHHDYHHILHHHHHQNHH-PHSHSQRYSREEL 312
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 235 bits (599), Expect = 1e-61
Identities = 180/539 (33%), Positives = 262/539 (48%), Gaps = 125/539 (23%)
Query: 297 LDPDNEGELRHTRKREAPHVKNNAIIS--------LRKDLNEDDHHHE-CLNVTQLLKYY 347
L P G+L ++ APH+ S L D + DH +E CLN +QLL +
Sbjct: 112 LGPSGWGDLEESK---APHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNF 168
Query: 348 GHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAW 407
G +P++ F LCPALLYQIDSR+CI D+ SA
Sbjct: 169 GLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDL---------------LSAL 213
Query: 408 ICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGH 467
+ +++ ++SL S L ++L+ ++ + LL FL ALAVGT+ GDALLHLLPH+Q G
Sbjct: 214 LQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG- 272
Query: 468 DHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGK 527
+HA G L E D + GL LGG++LLF++E+ + + +H RG
Sbjct: 273 ----RHAGPGG----------LPEKD-LGPGLSVLGGLFLLFVLENMLGLLRH----RGL 313
Query: 528 QKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEG 587
+ ++ R L L + + + L+PL + +G
Sbjct: 314 RPRCCRRKR------RNLETRNL-DPENGSGMALQPLQAAPE-------------PGAQG 353
Query: 588 QQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKH 647
Q+E KN +H A H G H H
Sbjct: 354 QRE---KN---------------------SQHPPALAPPGHQG--------------HSH 375
Query: 648 SHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVF 707
H G +I WMV++GDG+HN +DGLAIGAAFS G + G+ST++AVF
Sbjct: 376 GHQ--------------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVF 421
Query: 708 CHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVT 767
CHELPHELGDFA+LL++G++ ++ ++ +L+S + G ++G + +T W+F VT
Sbjct: 422 CHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVT 481
Query: 768 AGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIV 826
AG+FLYVALVDMLP +L P +LQ LGLL G +ML I L E++++
Sbjct: 482 AGVFLYVALVDMLPALLRPPEP------LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534
Score = 42.7 bits (99), Expect = 0.001
Identities = 20/37 (54%), Positives = 27/37 (72%)
Query: 56 AENEKKYYIEKLFERYGENGRLSFFGLEKLLTNLGLG 92
AE E+ +Y+ +LF YGENG L+ GL +LL +LGLG
Sbjct: 32 AEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLG 68
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 235 bits (599), Expect = 1e-61
Identities = 180/539 (33%), Positives = 262/539 (48%), Gaps = 125/539 (23%)
Query: 297 LDPDNEGELRHTRKREAPHVKNNAIIS--------LRKDLNEDDHHHE-CLNVTQLLKYY 347
L P G+L ++ APH+ S L D + DH +E CLN +QLL +
Sbjct: 112 LGPSGWGDLEESK---APHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNF 168
Query: 348 GHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAW 407
G +P++ F LCPALLYQIDSR+CI D+ SA
Sbjct: 169 GLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDL---------------LSAL 213
Query: 408 ICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGH 467
+ +++ ++SL S L ++L+ ++ + LL FL ALAVGT+ GDALLHLLPH+Q G
Sbjct: 214 LQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG- 272
Query: 468 DHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGK 527
+HA G L E D + GL LGG++LLF++E+ + + +H RG
Sbjct: 273 ----RHAGPGG----------LPEKD-LGPGLSVLGGLFLLFVLENMLGLLRH----RGL 313
Query: 528 QKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEG 587
+ ++ R L L + + + L+PL + +G
Sbjct: 314 RPRCCRRKR------RNLETRNL-DPENGSGMALQPLQAAPE-------------PGAQG 353
Query: 588 QQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKH 647
Q+E KN +H A H G H H
Sbjct: 354 QRE---KN---------------------SQHPPALAPPGHQG--------------HSH 375
Query: 648 SHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVF 707
H G +I WMV++GDG+HN +DGLAIGAAFS G + G+ST++AVF
Sbjct: 376 GHQ--------------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVF 421
Query: 708 CHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVT 767
CHELPHELGDFA+LL++G++ ++ ++ +L+S + G ++G + +T W+F VT
Sbjct: 422 CHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVT 481
Query: 768 AGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIV 826
AG+FLYVALVDMLP +L P +LQ LGLL G +ML I L E++++
Sbjct: 482 AGVFLYVALVDMLPALLRPPEP------LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534
Score = 42.7 bits (99), Expect = 0.001
Identities = 20/37 (54%), Positives = 27/37 (72%)
Query: 56 AENEKKYYIEKLFERYGENGRLSFFGLEKLLTNLGLG 92
AE E+ +Y+ +LF YGENG L+ GL +LL +LGLG
Sbjct: 32 AEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLG 68
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 219 bits (559), Expect = 6e-57
Identities = 151/490 (30%), Positives = 231/490 (47%), Gaps = 92/490 (18%)
Query: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
C + L + S I + CP +L Q+DSR C E+ ++N
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTS-------ENQENEENEQT 143
Query: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDAL 456
E+ W G++ +TVISL SLLG +VP + + +K LL + +ALA+GT+ +AL
Sbjct: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNAL 203
Query: 457 LHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIR 516
L+P + G + LE+Y V K V GG YL F E ++
Sbjct: 204 FQLIPEAFGFNP--------------------LEDY-YVSKSAVVFGGFYLFFFTEKILK 242
Query: 517 MFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTD-DSVVSED 575
+ +KQ E + L + D + ++ L D D ++ +
Sbjct: 243 IL-------------LKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQH 289
Query: 576 RLNETELTDLEGQQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTV 635
+E L+G+ + +EK+I + ++ DL A
Sbjct: 290 CSSE-----LDGKAP--------MVDEKVI-------VGSLSVQDLQA------------ 317
Query: 636 LRKHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAG 695
S C+ ++ + I +AWM+ + DG+HNF DGLAIGA+F+
Sbjct: 318 ---------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVS 362
Query: 696 LTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQY 755
+ GISTS+A+ C E PHELGDF +LL AGM+++QA+ +N LSA Y+G+ G G +
Sbjct: 363 VFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSH 422
Query: 756 ANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIM 815
+ WIFA+ GMFLY++L DM PEM ++E G + FI+QNLGLL GF IM
Sbjct: 423 FS--ANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILI-PFIIQNLGLLTGFTIM 479
Query: 816 LVIALYEDKI 825
+V+ +Y +I
Sbjct: 480 VVLTMYSGQI 489
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 219 bits (559), Expect = 6e-57
Identities = 151/490 (30%), Positives = 231/490 (47%), Gaps = 92/490 (18%)
Query: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
C + L + S I + CP +L Q+DSR C E+ ++N
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTS-------ENQENEENEQT 143
Query: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDAL 456
E+ W G++ +TVISL SLLG +VP + + +K LL + +ALA+GT+ +AL
Sbjct: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNAL 203
Query: 457 LHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIR 516
L+P + G + LE+Y V K V GG YL F E ++
Sbjct: 204 FQLIPEAFGFNP--------------------LEDY-YVSKSAVVFGGFYLFFFTEKILK 242
Query: 517 MFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTD-DSVVSED 575
+ +KQ E + L + D + ++ L D D ++ +
Sbjct: 243 IL-------------LKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQH 289
Query: 576 RLNETELTDLEGQQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTV 635
+E L+G+ + +EK+I + ++ DL A
Sbjct: 290 CSSE-----LDGKAP--------MVDEKVI-------VGSLSVQDLQA------------ 317
Query: 636 LRKHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAG 695
S C+ ++ + I +AWM+ + DG+HNF DGLAIGA+F+
Sbjct: 318 ---------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVS 362
Query: 696 LTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQY 755
+ GISTS+A+ C E PHELGDF +LL AGM+++QA+ +N LSA Y+G+ G G +
Sbjct: 363 VFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSH 422
Query: 756 ANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIM 815
+ WIFA+ GMFLY++L DM PEM ++E G + FI+QNLGLL GF IM
Sbjct: 423 FS--ANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILI-PFIIQNLGLLTGFTIM 479
Query: 816 LVIALYEDKI 825
+V+ +Y +I
Sbjct: 480 VVLTMYSGQI 489
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 218 bits (554), Expect = 2e-56
Identities = 148/490 (30%), Positives = 232/490 (47%), Gaps = 92/490 (18%)
Query: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
C + L + S I + CP +L Q+DSR C E+ ++N
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTS-------ENQENEENEQT 143
Query: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDAL 456
E+ W G +S+++I+L SLLGV+++P + F +LT+ +AL++GT+ +AL
Sbjct: 144 EEGRPSAVEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNAL 203
Query: 457 LHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIR 516
L+P + G + LE+Y V K V GG YL F E ++
Sbjct: 204 FQLIPEAFGFNP--------------------LEDY-YVSKSAVVFGGFYLFFFTEKILK 242
Query: 517 MFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTD-DSVVSED 575
+ +KQ E + L + D + ++ L D D ++ +
Sbjct: 243 IL-------------LKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQH 289
Query: 576 RLNETELTDLEGQQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTV 635
+E L+G+ + +EK+I + ++ DL A
Sbjct: 290 CSSE-----LDGKAP--------MVDEKVI-------VGSLSVQDLQA------------ 317
Query: 636 LRKHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAG 695
S C+ ++ + I +AWM+ + DG+HNF DGLAIGA+F+
Sbjct: 318 ---------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVS 362
Query: 696 LTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQY 755
+ GISTS+A+ C E PHELGDF +LL AGM+++QA+ +N LSA Y+G+ G G +
Sbjct: 363 VFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSH 422
Query: 756 ANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIM 815
+ WIFA+ GMFLY++L DM PEM ++E G + FI+QNLGLL GF IM
Sbjct: 423 FS--ANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILI-PFIIQNLGLLTGFTIM 479
Query: 816 LVIALYEDKI 825
+V+ +Y +I
Sbjct: 480 VVLTMYSGQI 489
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 188 bits (478), Expect = 2e-47
Identities = 131/445 (29%), Positives = 204/445 (45%), Gaps = 91/445 (20%)
Query: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
C + L + S I + CP +L Q+DSR C E+ ++N
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTS-------ENQENEENEQT 143
Query: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDAL 456
E+ W G++ +TVISL SLLG +VP + + +K LL + +ALA+GT+ +AL
Sbjct: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNAL 203
Query: 457 LHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIR 516
L+P + G + LE+Y V K V GG YL F E ++
Sbjct: 204 FQLIPEAFGFNP--------------------LEDY-YVSKSAVVFGGFYLFFFTEKILK 242
Query: 517 MFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTD-DSVVSED 575
+ +KQ E + L + D + ++ L D D ++ +
Sbjct: 243 IL-------------LKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQH 289
Query: 576 RLNETELTDLEGQQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTV 635
+E L+G+ + +EK+I + ++ DL A
Sbjct: 290 CSSE-----LDGKAP--------MVDEKVI-------VGSLSVQDLQA------------ 317
Query: 636 LRKHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAG 695
S C+ ++ + I +AWM+ + DG+HNF DGLAIGA+F+
Sbjct: 318 ---------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVS 362
Query: 696 LTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQY 755
+ GISTS+A+ C E PHELGDF +LL AGM+++QA+ +N LSA Y+G+ G G +
Sbjct: 363 VFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSH 422
Query: 756 ANNITLWIFAVTAGMFLYVALVDML 780
+ WIFA+ GMFLY++L DM+
Sbjct: 423 FS--ANWIFALAGGMFLYISLADMM 445
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 161 bits (408), Expect = 2e-39
Identities = 80/169 (47%), Positives = 119/169 (70%), Gaps = 7/169 (4%)
Query: 657 SGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716
+ S+ K I+ +A M+++GD +HNF+DGLAIGAAFS+ G++T+IA+ CHE+PHE+G
Sbjct: 528 TASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMG 587
Query: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVAL 776
DFAVLL +G+++K AI+ N +S++ A++G+ IG +V + WIF VTAGMFLY++L
Sbjct: 588 DFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA-DPCVQDWIFTVTAGMFLYLSL 646
Query: 777 VDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
V+MLPEM H P F+LQN GL+ G+ +L++A+YE I
Sbjct: 647 VEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNI 689
Score = 69.3 bits (168), Expect = 1e-11
Identities = 58/193 (30%), Positives = 90/193 (46%), Gaps = 29/193 (15%)
Query: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
C + QL++ + S IS + F + P ++ Q+ S C H K ++ L P
Sbjct: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSC--HLPK------DQQAKLPP 361
Query: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGC---FKFLLTFLVALAVGTMSG 453
G S +++T+++L S+LG LV + C ++ +L V LAVGT+SG
Sbjct: 362 TTLEKYGYST-----VAVTLLTLGSMLGTALV--LFHSCEENYRLILQLFVGLAVGTLSG 414
Query: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEH 513
DALLHL+P G H Q A GH H E + K + +GGI+ F+IE
Sbjct: 415 DALLHLIPQVLGLH---KQEAPEFGHFH--------ESKGHIWKLMGLIGGIHGFFLIEK 463
Query: 514 CIRMFKHYKQQRG 526
C + ++G
Sbjct: 464 CFILLVSPNDKQG 476
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 161 bits (408), Expect = 2e-39
Identities = 80/169 (47%), Positives = 119/169 (70%), Gaps = 7/169 (4%)
Query: 657 SGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716
+ S+ K I+ +A M+++GD +HNF+DGLAIGAAFS+ G++T+IA+ CHE+PHE+G
Sbjct: 491 TASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMG 550
Query: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVAL 776
DFAVLL +G+++K AI+ N +S++ A++G+ IG +V + WIF VTAGMFLY++L
Sbjct: 551 DFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA-DPCVQDWIFTVTAGMFLYLSL 609
Query: 777 VDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
V+MLPEM H P F+LQN GL+ G+ +L++A+YE I
Sbjct: 610 VEMLPEMTHVQTQR------PWMMFLLQNFGLILGWLSLLLLAIYEQNI 652
Score = 68.9 bits (167), Expect = 2e-11
Identities = 57/181 (31%), Positives = 86/181 (47%), Gaps = 29/181 (16%)
Query: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
C + QL++ + S IS + F + P ++ Q+ S C H K ++ L P
Sbjct: 310 CFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSC--HLPK------DQQAKLPP 361
Query: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGC---FKFLLTFLVALAVGTMSG 453
G S +++T+++L S+LG LV + C ++ +L V LAVGT+SG
Sbjct: 362 TTLEKYGYST-----VAVTLLTLGSMLGTALV--LFHSCEENYRLILQLFVGLAVGTLSG 414
Query: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEH 513
DALLHL+P G H Q A GH H E + K + +GGI+ F+IE
Sbjct: 415 DALLHLIPQVLGLH---KQEAPEFGHFH--------ESKGHIWKLMGLIGGIHGFFLIEK 463
Query: 514 C 514
C
Sbjct: 464 C 464
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 161 bits (407), Expect = 3e-39
Identities = 93/214 (43%), Positives = 126/214 (58%), Gaps = 38/214 (17%)
Query: 645 HKHSHHSHG--------------PCHSGS--DL---KETGIAN------------IAWMV 673
H H HSHG P H GS DL + + N + +M+
Sbjct: 416 HSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMI 475
Query: 674 IMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIV 733
+GD +HNF+DGLA+GAAF++ G++TS+AVFCHELPHELGDFA LL AG++V+QA++
Sbjct: 476 TLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALL 535
Query: 734 YNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEH 793
NL SA+ A+ G+ + AVG + WI AV G+FLYVAL DMLP ML
Sbjct: 536 LNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPR--- 591
Query: 794 GFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVF 827
P F+L N+GLL G+ ++L+++LYED I F
Sbjct: 592 ---PWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 622
Score = 55.1 bits (131), Expect = 3e-07
Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 14/137 (10%)
Query: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
CL+ ++ YG + ++ + + L PALL Q S C + + +++ +
Sbjct: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSER--- 301
Query: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIIN-QGCFKFLLTFLVALAVGTMSGDA 455
++ G ++ +I L ++ G++L+ +G ++L ++LAVG ++GDA
Sbjct: 302 ----------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDA 351
Query: 456 LLHLLPHSQGGHDHSHQ 472
+LHL P G H HS +
Sbjct: 352 VLHLTPKVLGLHTHSEE 368
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 161 bits (407), Expect = 3e-39
Identities = 93/214 (43%), Positives = 126/214 (58%), Gaps = 38/214 (17%)
Query: 645 HKHSHHSHG--------------PCHSGS--DL---KETGIAN------------IAWMV 673
H H HSHG P H GS DL + + N + +M+
Sbjct: 441 HSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMI 500
Query: 674 IMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIV 733
+GD +HNF+DGLA+GAAF++ G++TS+AVFCHELPHELGDFA LL AG++V+QA++
Sbjct: 501 TLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALL 560
Query: 734 YNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEH 793
NL SA+ A+ G+ + AVG + WI AV G+FLYVAL DMLP ML
Sbjct: 561 LNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPR--- 616
Query: 794 GFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVF 827
P F+L N+GLL G+ ++L+++LYED I F
Sbjct: 617 ---PWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 647
Score = 55.1 bits (131), Expect = 3e-07
Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 14/137 (10%)
Query: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
CL+ ++ YG + ++ + + L PALL Q S C + + +++ +
Sbjct: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSER--- 326
Query: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIIN-QGCFKFLLTFLVALAVGTMSGDA 455
++ G ++ +I L ++ G++L+ +G ++L ++LAVG ++GDA
Sbjct: 327 ----------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDA 376
Query: 456 LLHLLPHSQGGHDHSHQ 472
+LHL P G H HS +
Sbjct: 377 VLHLTPKVLGLHTHSEE 393
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 150 bits (378), Expect = 6e-36
Identities = 81/172 (47%), Positives = 107/172 (62%), Gaps = 6/172 (3%)
Query: 655 CHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHE 714
C G L E G IAWM+ + D +HNF DGLAIGA+ + L G+STSIA+ C E PHE
Sbjct: 291 CLKGPKLSEIG--TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348
Query: 715 LGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVG-QYANNITLWIFAVTAGMFLY 773
LGDF +LL AGM+ +QA+++N LSA Y+G+ G VG +A NI IFA+ GMFLY
Sbjct: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLY 405
Query: 774 VALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
++L DM PEM + F++QN G+L GF +L+I LY +I
Sbjct: 406 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 457
Score = 87.8 bits (216), Expect = 4e-17
Identities = 58/195 (29%), Positives = 90/195 (46%), Gaps = 38/195 (19%)
Query: 333 HHHECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDK 392
H ++CL ++ +G + I++ F+ +CPA+L Q++ C ED K K
Sbjct: 70 HFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC---------EDRPKHK 120
Query: 393 NLVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMS 452
E W G +S+T+I+L SLLG+IL P+I + F +LTF V LA+GT+
Sbjct: 121 TRPSHSEV------WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLF 174
Query: 453 GDALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDA-VLKGLVALGGIYLLFII 511
+A+ L+P + G F + D+ V K + GG YLLF
Sbjct: 175 SNAIFQLIPEAFG----------------------FDPKVDSYVEKAVAVFGGFYLLFFF 212
Query: 512 EHCIRMFKHYKQQRG 526
E ++M Q G
Sbjct: 213 ERMLKMLLKTYGQNG 227
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 150 bits (378), Expect = 6e-36
Identities = 81/172 (47%), Positives = 107/172 (62%), Gaps = 6/172 (3%)
Query: 655 CHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHE 714
C G L E G IAWM+ + D +HNF DGLAIGA+ + L G+STSIA+ C E PHE
Sbjct: 224 CLKGPKLSEIG--TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 281
Query: 715 LGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVG-QYANNITLWIFAVTAGMFLY 773
LGDF +LL AGM+ +QA+++N LSA Y+G+ G VG +A NI IFA+ GMFLY
Sbjct: 282 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLY 338
Query: 774 VALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
++L DM PEM + F++QN G+L GF +L+I LY +I
Sbjct: 339 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 390
Score = 87.0 bits (214), Expect = 6e-17
Identities = 58/194 (29%), Positives = 89/194 (45%), Gaps = 38/194 (19%)
Query: 334 HHECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKN 393
H +CL ++ +G + I++ F+ +CPA+L Q++ C ED K K
Sbjct: 4 HAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC---------EDRPKHKT 54
Query: 394 LVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSG 453
E W G +S+T+I+L SLLG+IL P+I + F +LTF V LA+GT+
Sbjct: 55 RPSHSEV------WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFS 108
Query: 454 DALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDA-VLKGLVALGGIYLLFIIE 512
+A+ L+P + G F + D+ V K + GG YLLF E
Sbjct: 109 NAIFQLIPEAFG----------------------FDPKVDSYVEKAVAVFGGFYLLFFFE 146
Query: 513 HCIRMFKHYKQQRG 526
++M Q G
Sbjct: 147 RMLKMLLKTYGQNG 160
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 150 bits (378), Expect = 6e-36
Identities = 81/172 (47%), Positives = 107/172 (62%), Gaps = 6/172 (3%)
Query: 655 CHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHE 714
C G L E G IAWM+ + D +HNF DGLAIGA+ + L G+STSIA+ C E PHE
Sbjct: 291 CLKGPKLSEIG--TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348
Query: 715 LGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVG-QYANNITLWIFAVTAGMFLY 773
LGDF +LL AGM+ +QA+++N LSA Y+G+ G VG +A NI IFA+ GMFLY
Sbjct: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLY 405
Query: 774 VALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKI 825
++L DM PEM + F++QN G+L GF +L+I LY +I
Sbjct: 406 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 457
Score = 87.8 bits (216), Expect = 4e-17
Identities = 58/195 (29%), Positives = 90/195 (46%), Gaps = 38/195 (19%)
Query: 333 HHHECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDK 392
H ++CL ++ +G + I++ F+ +CPA+L Q++ C ED K K
Sbjct: 70 HFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC---------EDRPKHK 120
Query: 393 NLVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMS 452
E W G +S+T+I+L SLLG+IL P+I + F +LTF V LA+GT+
Sbjct: 121 TRPSHSEV------WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLF 174
Query: 453 GDALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDA-VLKGLVALGGIYLLFII 511
+A+ L+P + G F + D+ V K + GG YLLF
Sbjct: 175 SNAIFQLIPEAFG----------------------FDPKVDSYVEKAVAVFGGFYLLFFF 212
Query: 512 EHCIRMFKHYKQQRG 526
E ++M Q G
Sbjct: 213 ERMLKMLLKTYGQNG 227
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 136 bits (343), Expect = 7e-32
Identities = 69/130 (53%), Positives = 88/130 (67%), Gaps = 6/130 (4%)
Query: 655 CHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHE 714
C G L E G IAWM+ + D +HNF DGLAIGA+ + L G+STSIA+ C E PHE
Sbjct: 291 CLKGPKLSEIG--TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHE 348
Query: 715 LGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVG-QYANNITLWIFAVTAGMFLY 773
LGDF +LL AGM+ +QA+++N LSA Y+G+ G VG +A NI IFA+ GMFLY
Sbjct: 349 LGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLY 405
Query: 774 VALVDMLPEM 783
++L DM PEM
Sbjct: 406 ISLADMFPEM 415
Score = 87.8 bits (216), Expect = 4e-17
Identities = 58/195 (29%), Positives = 90/195 (46%), Gaps = 38/195 (19%)
Query: 333 HHHECLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDK 392
H ++CL ++ +G + I++ F+ +CPA+L Q++ C ED K K
Sbjct: 70 HFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC---------EDRPKHK 120
Query: 393 NLVPEDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMS 452
E W G +S+T+I+L SLLG+IL P+I + F +LTF V LA+GT+
Sbjct: 121 TRPSHSEV------WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLF 174
Query: 453 GDALLHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDA-VLKGLVALGGIYLLFII 511
+A+ L+P + G F + D+ V K + GG YLLF
Sbjct: 175 SNAIFQLIPEAFG----------------------FDPKVDSYVEKAVAVFGGFYLLFFF 212
Query: 512 EHCIRMFKHYKQQRG 526
E ++M Q G
Sbjct: 213 ERMLKMLLKTYGQNG 227
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 112 bits (281), Expect = 1e-24
Identities = 121/417 (29%), Positives = 175/417 (41%), Gaps = 88/417 (21%)
Query: 462 HSQGGHDHSHQHAH------GHGHSHGHESNKFLE--------EYDAVLKGLVALGGIYL 507
H H HSH ++H GHGH H H + E + DAV ALG L
Sbjct: 85 HEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVL 144
Query: 508 LFIIEHCIRMFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLA-- 565
+ + +F + + + Q G L D L+ P + L+P +
Sbjct: 145 ISAAPFFV-LFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHA----LEPHSHH 199
Query: 566 -----GTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIEEEKII-----DHSHSDGLHT 615
G S + + L L G +L +E K + H HS G
Sbjct: 200 TLEQPGHGHSHSGQGPILSVGLWVLSGIVA-----FLVVE--KFVRHVKGGHGHSHGHGH 252
Query: 616 IHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHH-----------SHGPCHS------- 657
H H +H H + ++ K + + K + GP
Sbjct: 253 AHSHT--RGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEK 310
Query: 658 -GSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716
G DL+ +G N+A D HNF+DGLAIGA+F G GI T++ V HE+PHE+G
Sbjct: 311 RGLDLRVSGYLNLA-----ADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
Query: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAV------GQYANNIT-----LWIFA 765
DFA+L+++G + KQA+ LL+A +G L GTA G + I W+
Sbjct: 366 DFAILVQSGCSKKQAMRLQLLTA----VGALAGTACALLTEGGAVGSEIAGGAGPGWVLP 421
Query: 766 VTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYE 822
TAG F+YVA V +LPE+L P+ Q +L+ LGLL G +M++IA E
Sbjct: 422 FTAGGFIYVATVSVLPELLREAS--------PL-QSLLEVLGLLGGVIMMVLIAHLE 469
Score = 57.8 bits (138), Expect = 4e-08
Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 407 WICGIISITVISLLSLLGVILVPI-INQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQG 465
W + + +IS + L+P+ N + LL L++ A G + GDA LHL+PH+
Sbjct: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
Query: 466 GHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFK 519
H H GHGHSH + + GL L GI ++E +R K
Sbjct: 195 PHSHHTLEQPGHGHSHSGQG-------PILSVGLWVLSGIVAFLVVEKFVRHVK 241
Score = 41.2 bits (95), Expect = 0.004
Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 20/106 (18%)
Query: 101 HEDLGHDHVSHLDILAVQEGKHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETV 160
H+DL D H + ++ H HSH H H H H S+ H D
Sbjct: 35 HDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTH--------ESIWHGHTHDHDH----- 81
Query: 161 EVSVKSDDKHMHDHNHRLRH---HHRLHHHLDHNNTHHFHNDSITP 203
+D H H H+H H +HR H H DH ++H + +S P
Sbjct: 82 --GHSHEDLH-HGHSHGYSHESLYHRGHGH-DHEHSHGGYGESGAP 123
Score = 37.4 bits (85), Expect = 0.058
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 12/56 (21%)
Query: 607 HSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSH------HSHGPCH 656
HSH D H H+ AH H ++++ H H H HSH HSHG H
Sbjct: 49 HSHEDFHHG------HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSH 98
Score = 36.2 bits (82), Expect = 0.13
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
Query: 607 HSHSDGLHTIHEHDLHAAAHNH-HGENKTVLRK-HNHQWHHK---HSHHSHGPCHSGSDL 661
HSH+ G HE H H+H HG + L H+H + H+ H H H HS
Sbjct: 58 HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
Query: 662 KETGIANI 669
E+G I
Sbjct: 118 GESGAPGI 125
Score = 35.8 bits (81), Expect = 0.17
Identities = 13/24 (54%), Positives = 14/24 (58%)
Query: 458 HLLPHSQGGHDHSHQHAHGHGHSH 481
H HS H H HAHGHGH+H
Sbjct: 45 HSHRHSHEDFHHGHSHAHGHGHTH 68
Score = 35.4 bits (80), Expect = 0.22
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 18/55 (32%)
Query: 446 LAVGTMSGDALLHLLPHSQGGHD------------HSHQHA-----HGHGHSHGH 483
+AVG ++ A L LL GGHD HSH+H+ HGH H+HGH
Sbjct: 11 VAVGLLTW-ATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGH 64
Score = 35.0 bits (79), Expect = 0.29
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 12/60 (20%)
Query: 611 DGLHTIHEHDLHAAAHN------HHGENKTVLRKHNHQ--WH-HKHSH---HSHGPCHSG 658
D LH + D H +H HHG + H H+ WH H H H HSH H G
Sbjct: 32 DDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHG 91
Score = 34.3 bits (77), Expect = 0.49
Identities = 12/24 (50%), Positives = 13/24 (54%)
Query: 462 HSQGGHDHSHQHAHGHGHSHGHES 485
H D H H+H HGH H HES
Sbjct: 47 HRHSHEDFHHGHSHAHGHGHTHES 70
Score = 30.0 bits (66), Expect = 9.2
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 119 EGKHFHSHNHQHSHNHL-NSENQTVTSVSTKRNHKC-DPEKET 159
+G H HSH H H+H+H S STK + EKET
Sbjct: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKET 283
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 112 bits (281), Expect = 1e-24
Identities = 121/417 (29%), Positives = 175/417 (41%), Gaps = 88/417 (21%)
Query: 462 HSQGGHDHSHQHAH------GHGHSHGHESNKFLE--------EYDAVLKGLVALGGIYL 507
H H HSH ++H GHGH H H + E + DAV ALG L
Sbjct: 85 HEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVL 144
Query: 508 LFIIEHCIRMFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLA-- 565
+ + +F + + + Q G L D L+ P + L+P +
Sbjct: 145 ISAAPFFV-LFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHA----LEPHSHH 199
Query: 566 -----GTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIEEEKII-----DHSHSDGLHT 615
G S + + L L G +L +E K + H HS G
Sbjct: 200 TLEQPGHGHSHSGQGPILSVGLWVLSGIVA-----FLVVE--KFVRHVKGGHGHSHGHGH 252
Query: 616 IHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHH-----------SHGPCHS------- 657
H H +H H + ++ K + + K + GP
Sbjct: 253 AHSHT--RGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEK 310
Query: 658 -GSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELG 716
G DL+ +G N+A D HNF+DGLAIGA+F G GI T++ V HE+PHE+G
Sbjct: 311 RGLDLRVSGYLNLA-----ADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
Query: 717 DFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAV------GQYANNIT-----LWIFA 765
DFA+L+++G + KQA+ LL+A +G L GTA G + I W+
Sbjct: 366 DFAILVQSGCSKKQAMRLQLLTA----VGALAGTACALLTEGGAVGSEIAGGAGPGWVLP 421
Query: 766 VTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYE 822
TAG F+YVA V +LPE+L P+ Q +L+ LGLL G +M++IA E
Sbjct: 422 FTAGGFIYVATVSVLPELLREAS--------PL-QSLLEVLGLLGGVIMMVLIAHLE 469
Score = 57.8 bits (138), Expect = 4e-08
Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 407 WICGIISITVISLLSLLGVILVPI-INQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQG 465
W + + +IS + L+P+ N + LL L++ A G + GDA LHL+PH+
Sbjct: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
Query: 466 GHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFK 519
H H GHGHSH + + GL L GI ++E +R K
Sbjct: 195 PHSHHTLEQPGHGHSHSGQG-------PILSVGLWVLSGIVAFLVVEKFVRHVK 241
Score = 41.2 bits (95), Expect = 0.004
Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 20/106 (18%)
Query: 101 HEDLGHDHVSHLDILAVQEGKHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETV 160
H+DL D H + ++ H HSH H H H H S+ H D
Sbjct: 35 HDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTH--------ESIWHGHTHDHDH----- 81
Query: 161 EVSVKSDDKHMHDHNHRLRH---HHRLHHHLDHNNTHHFHNDSITP 203
+D H H H+H H +HR H H DH ++H + +S P
Sbjct: 82 --GHSHEDLH-HGHSHGYSHESLYHRGHGH-DHEHSHGGYGESGAP 123
Score = 37.4 bits (85), Expect = 0.058
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 12/56 (21%)
Query: 607 HSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSH------HSHGPCH 656
HSH D H H+ AH H ++++ H H H HSH HSHG H
Sbjct: 49 HSHEDFHHG------HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSH 98
Score = 36.2 bits (82), Expect = 0.13
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
Query: 607 HSHSDGLHTIHEHDLHAAAHNH-HGENKTVLRK-HNHQWHHK---HSHHSHGPCHSGSDL 661
HSH+ G HE H H+H HG + L H+H + H+ H H H HS
Sbjct: 58 HSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGY 117
Query: 662 KETGIANI 669
E+G I
Sbjct: 118 GESGAPGI 125
Score = 35.8 bits (81), Expect = 0.17
Identities = 13/24 (54%), Positives = 14/24 (58%)
Query: 458 HLLPHSQGGHDHSHQHAHGHGHSH 481
H HS H H HAHGHGH+H
Sbjct: 45 HSHRHSHEDFHHGHSHAHGHGHTH 68
Score = 35.4 bits (80), Expect = 0.22
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 18/55 (32%)
Query: 446 LAVGTMSGDALLHLLPHSQGGHD------------HSHQHA-----HGHGHSHGH 483
+AVG ++ A L LL GGHD HSH+H+ HGH H+HGH
Sbjct: 11 VAVGLLTW-ATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGH 64
Score = 35.0 bits (79), Expect = 0.29
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 12/60 (20%)
Query: 611 DGLHTIHEHDLHAAAHN------HHGENKTVLRKHNHQ--WH-HKHSH---HSHGPCHSG 658
D LH + D H +H HHG + H H+ WH H H H HSH H G
Sbjct: 32 DDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHG 91
Score = 34.3 bits (77), Expect = 0.49
Identities = 12/24 (50%), Positives = 13/24 (54%)
Query: 462 HSQGGHDHSHQHAHGHGHSHGHES 485
H D H H+H HGH H HES
Sbjct: 47 HRHSHEDFHHGHSHAHGHGHTHES 70
Score = 30.0 bits (66), Expect = 9.2
Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 119 EGKHFHSHNHQHSHNHL-NSENQTVTSVSTKRNHKC-DPEKET 159
+G H HSH H H+H+H S STK + EKET
Sbjct: 241 KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKET 283
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 86.7 bits (213), Expect = 8e-17
Identities = 51/155 (32%), Positives = 86/155 (55%), Gaps = 11/155 (7%)
Query: 671 WMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQ 730
++ ++ + I NF+ GLA+ A+F G+ T++A+ HE+PHE+GDFA+LL+AG
Sbjct: 219 YLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWS 278
Query: 731 AIVYNLLSAMMAYI--GMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDG 788
A L +A+ + G I T + W+ T+G FLY+ALV++LP++L
Sbjct: 279 AAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLL---- 334
Query: 789 DNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYED 823
EE + + Q +L L G +M++ +L+ D
Sbjct: 335 -EEEDPWRSLQQLLL----LCAGIVVMVLFSLFVD 364
Score = 33.9 bits (76), Expect = 0.64
Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 20/127 (15%)
Query: 407 WICGIISITVISLLSLLGVILVPI-----INQGCFKFLLTFLVALAVGTMSGDALLHLLP 461
WIC ++ ++ L + ++++P+ + + L L++ A+G + G+ LHLLP
Sbjct: 68 WICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLP 127
Query: 462 HSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHY 521
+ A+ S G E ++ GL + GI +E +MF
Sbjct: 128 EA---------WAYTCSASPGGEGQSLQQQQQL---GLWVIAGILTFLALE---KMFLDS 172
Query: 522 KQQRGKQ 528
K++ Q
Sbjct: 173 KEEGTSQ 179
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 83.2 bits (204), Expect = 9e-16
Identities = 52/164 (31%), Positives = 87/164 (53%), Gaps = 22/164 (13%)
Query: 671 WMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQ 730
++ ++ + I NF+ GLA+ A+F G+ T++A+ HE+PHE+GDFA+LL+AG
Sbjct: 219 YLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWS 278
Query: 731 AIVYNLLSAMMAYIGMLIGTAV-----------GQYANNITLWIFAVTAGMFLYVALVDM 779
A L +A+ +G G A+ A W+ T+G FLY+ALV++
Sbjct: 279 AAKLQLSTALGGLLG--AGFAICTQSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNV 336
Query: 780 LPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYED 823
LP++L EE + + Q +L L G +M++ +L+ D
Sbjct: 337 LPDLL-----EEEDPWRSLQQLLL----LCAGIVVMVLFSLFVD 371
Score = 33.9 bits (76), Expect = 0.64
Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 20/127 (15%)
Query: 407 WICGIISITVISLLSLLGVILVPI-----INQGCFKFLLTFLVALAVGTMSGDALLHLLP 461
WIC ++ ++ L + ++++P+ + + L L++ A+G + G+ LHLLP
Sbjct: 68 WICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLP 127
Query: 462 HSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHY 521
+ A+ S G E ++ GL + GI +E +MF
Sbjct: 128 EA---------WAYTCSASPGGEGQSLQQQQQL---GLWVIAGILTFLALE---KMFLDS 172
Query: 522 KQQRGKQ 528
K++ Q
Sbjct: 173 KEEGTSQ 179
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 59.7 bits (143), Expect = 1e-08
Identities = 55/212 (25%), Positives = 90/212 (42%), Gaps = 41/212 (19%)
Query: 611 DGLHTIHEHDL----HAAAHNHH------GENKTVLRKHNHQWHHKHSH----------- 649
+G+H ++E L H A+ H+ K+V+ +H H H H
Sbjct: 57 EGVHALYEDILEGKHHQASETHNVIASDKAAEKSVVHEHEHSHDHTQLHAYIGVSLVLGF 116
Query: 650 ----------HSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTG- 698
+SH HS D + +N +G +H +DG+A+GAA S T
Sbjct: 117 VFMLLVDQIGNSH--VHSTDDPEAARSSNSKITTTLGLVVHAAADGVALGAAASTSQTSV 174
Query: 699 GISTSIAVFCHELPHELGDFAVLLKAGMTV----KQAIVYNLLS---AMMAYIGMLIGTA 751
+ +A+ H+ P G + L+ AG+ K +V+ L + +M+ Y+G+ +
Sbjct: 175 QLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPVMSMVTYLGLSKSSK 234
Query: 752 VGQYANNITLWIFAVTAGMFLYVALVDMLPEM 783
N T +AG FLYVA V +LPE+
Sbjct: 235 EALSEVNATGVAMLFSAGTFLYVATVHVLPEV 266
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 47.8 bits (112), Expect = 4e-05
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 8/125 (6%)
Query: 672 MVIMGDGIHNFSDGLAIGAAF-------SAGLTGGISTSIAVFCHELPHELGDFAVLLKA 724
++I+ IHN +GLA+G F SA + +I + P L L A
Sbjct: 196 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 255
Query: 725 GMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPE-M 783
G + +A Y LS M+ + + G A I + A AG +YV + D++PE
Sbjct: 256 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQ 315
Query: 784 LHGDG 788
+ G+G
Sbjct: 316 ISGNG 320
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 47.8 bits (112), Expect = 4e-05
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 8/125 (6%)
Query: 672 MVIMGDGIHNFSDGLAIGAAF-------SAGLTGGISTSIAVFCHELPHELGDFAVLLKA 724
++I+ IHN +GLA+G F SA + +I + P L L A
Sbjct: 189 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 248
Query: 725 GMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPE-M 783
G + +A Y LS M+ + + G A I + A AG +YV + D++PE
Sbjct: 249 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQ 308
Query: 784 LHGDG 788
+ G+G
Sbjct: 309 ISGNG 313
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 45.8 bits (107), Expect = 2e-04
Identities = 56/268 (20%), Positives = 87/268 (32%), Gaps = 48/268 (17%)
Query: 90 GLGERKVVEINHE-DLGHDHVSHLDILAVQEGKHFHSH-NHQHSHNHLNSENQTVTSVST 147
GL E E+ H DH ++ + G HF SH + + ++ E +
Sbjct: 48 GLSEEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHR 107
Query: 148 KRNHKCDPEKETVEVSV--------------KSDDKHMHDHNHRLRHHHRLHHHLDHN-- 191
++HK E + E D + +H H L H R H H D +
Sbjct: 108 SQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSH-RSHSHQDEDED 166
Query: 192 ----NTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKSNENSEVI 247
+ HH H + RG + E + +E+ + + + R SE
Sbjct: 167 EVVSSEHHHH--ILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSE-- 222
Query: 248 TPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPDNEGELRH 307
+ D + + H H P H H E + D D D D E RH
Sbjct: 223 -----EDEDVSDGHHH---------HGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRH 268
Query: 308 TRKREAPHVKNNAIISLRKDLNEDDHHH 335
R H + +D + D HH
Sbjct: 269 QAHRHQGH-------GIEEDEDVSDGHH 289
Score = 41.6 bits (96), Expect = 0.003
Identities = 63/290 (21%), Positives = 99/290 (34%), Gaps = 68/290 (23%)
Query: 101 HEDLGHDHVSHLDILAVQEGKHFHSHNHQHSHNHLNSENQTVTS-------VSTKRNHKC 153
H GH D V +G H H +H+H + + ++ VS + H+
Sbjct: 214 HRHRGHGSEEDED---VSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQA 270
Query: 154 DPEKE--TVEVSVKSDDKHMHDHNHRLRHH---------------HRLHHHLDH------ 190
+ E SD H D +HR R H H+ H H DH
Sbjct: 271 HRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVE 330
Query: 191 --NNTHHFH-NDSITPSERGEPSNEP-STE-------------TNKTQEQSDVKLPKG-- 231
+ HH H D R E +E STE ++ +E+ ++ + G
Sbjct: 331 AVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHY 390
Query: 232 --KRKKKGRKSNEN--SEVITPGFPPNHDQGEQYEHNRVHKPDRVHN-PGHSHVHLPERN 286
+ +G KS+E + P +H E + + H P H H E
Sbjct: 391 VASHQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEET 450
Query: 287 GHDPGRGHQDLDPDNEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHE 336
GH +++ G HT ++ H LRKD +E++ E
Sbjct: 451 GHGQRGSIKEMSHHPPG---HTVVKDRSH--------LRKDDSEEEKEKE 489
Score = 37.0 bits (84), Expect = 0.075
Identities = 52/269 (19%), Positives = 93/269 (34%), Gaps = 37/269 (13%)
Query: 98 EINHEDLGHDHVSHLDILAVQEGKHFHSHNHQHSHNHLNSENQTVTSVSTKRNHK----- 152
E H+ H ++ AV H H +H+H + E++ VST+R H+
Sbjct: 313 EYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDE---DVSTERWHQGPQHV 369
Query: 153 ----CDPEKETVEVSV--------------KSDDKHMHD-HNHRLRHHHRLHHHLDHNNT 193
D E+E E++V KSD++ D + + HHH HH +
Sbjct: 370 HHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHH--HHRVPREED 427
Query: 194 HHFHND--SITPSERGEPSNEPSTETNKTQEQSDVKLPKG----KRKKKGRKSNENSEVI 247
+ PS R +E + + + P G K + RK + E
Sbjct: 428 EEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKE 487
Query: 248 TPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPDNEGELRH 307
P +H++ + E + + H E GH ++ + +++ E
Sbjct: 488 KEEDPGSHEEDD--ESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEE 545
Query: 308 TRKREAPHVKNNAIISLRKDLNEDDHHHE 336
E + L D +E++ E
Sbjct: 546 EEDEERREERAEVGAPLSPDHSEEEEEEE 574
>gi|156415986 solute carrier family 39 (zinc transporter), member 2
[Homo sapiens]
Length = 309
Score = 44.3 bits (103), Expect = 5e-04
Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 16/147 (10%)
Query: 645 HKHSHHSHG--PCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGIST 702
H HSHG P S L+ A ++++ H+ +GLA+G + T +
Sbjct: 145 HIFELHSHGHLPSPSKGPLR-------ALVLLLSLSFHSVFEGLAVGLQPTVAAT--VQL 195
Query: 703 SIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAV----GQYANN 758
+AV H+ G L+ G + + A+ LL A+M+ +G+ +G AV +
Sbjct: 196 CLAVLAHKGLVVFGVGMRLVHLGTSSRWAVFSILLLALMSPLGLAVGLAVTGGDSEGGRG 255
Query: 759 ITLWIF-AVTAGMFLYVALVDMLPEML 784
+ + V AG FLYV +++LP L
Sbjct: 256 LAQAVLEGVAAGTFLYVTFLEILPREL 282
>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
Length = 1073
Score = 43.5 bits (101), Expect = 8e-04
Identities = 31/137 (22%), Positives = 52/137 (37%), Gaps = 7/137 (5%)
Query: 100 NHEDLGHDHVSHLDI-----LAVQEGKHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCD 154
+++DL H L +++ S LN+ + T + N
Sbjct: 137 SYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHL 196
Query: 155 PEKETVEVSVKSDDKHMHDHNHRLRHHHRLHH--HLDHNNTHHFHNDSITPSERGEPSNE 212
P+ + ++ + + H H L HHH++HH HL H + H H + S G P +
Sbjct: 197 PQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSS 256
Query: 213 PSTETNKTQEQSDVKLP 229
P + T SD P
Sbjct: 257 PVSRKLSTTGSSDSITP 273
>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
Length = 525
Score = 42.7 bits (99), Expect = 0.001
Identities = 22/58 (37%), Positives = 23/58 (39%), Gaps = 10/58 (17%)
Query: 607 HSHSDGLHTIHEHDLHAA-AHNHHGENKTVLRKHNHQWHHKHSHHSHG---PCHSGSD 660
H H H HEHD H H HH H+ HH H HH HG CH D
Sbjct: 362 HGHHPHAHHPHEHDTHRQHPHGHHPHG------HHPHGHHPHGHHPHGHHPHCHDFQD 413
Score = 42.0 bits (97), Expect = 0.002
Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 2/49 (4%)
Query: 607 HSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWH--HKHSHHSHG 653
HSH++ +H H H+ + HG + H H H H H HH HG
Sbjct: 340 HSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHG 388
Score = 40.0 bits (92), Expect = 0.009
Identities = 18/49 (36%), Positives = 20/49 (40%), Gaps = 2/49 (4%)
Query: 607 HSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQ--WHHKHSHHSHG 653
H H H H H H AH+ H + H H HH H HH HG
Sbjct: 350 HPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHG 398
Score = 33.9 bits (76), Expect = 0.64
Identities = 22/81 (27%), Positives = 30/81 (37%), Gaps = 5/81 (6%)
Query: 575 DRLNETELTDLEGQQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKT 634
D + E DLE SP + E +H + +G+ H H H K
Sbjct: 221 DLFYDVEALDLE----SPKNLVINCEVFDPQEHENINGVPPHLGHPFHWGGHERSSTTKP 276
Query: 635 VLRKH-NHQWHHKHSHHSHGP 654
+ H + HH H H HGP
Sbjct: 277 PFKPHGSRDHHHPHKPHEHGP 297
Score = 33.5 bits (75), Expect = 0.83
Identities = 38/173 (21%), Positives = 54/173 (31%), Gaps = 28/173 (16%)
Query: 172 HDHNHRLRHHHRLHHHLDHNNTH--HFHNDSITPSER----GEPSNEPSTETNKTQEQSD 225
H+ + + + H DH++ H H H P ER G P + S
Sbjct: 268 HERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSC 327
Query: 226 VKLPKGKRKKKGRKSNENSEVITPGFPPNHDQGEQYEHNRVHKPDRV---------HNPG 276
G + N NS + P +H+Q H H P H+P
Sbjct: 328 QHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPH 387
Query: 277 HSHVHLPERNGHDPGRGHQ------------DLDPDNEGELRHTRKREAPHVK 317
H H +GH P GH D P N+G H H++
Sbjct: 388 GHHPHGHHPHGHHP-HGHHPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLR 439
Score = 32.3 bits (72), Expect = 1.9
Identities = 20/78 (25%), Positives = 27/78 (34%), Gaps = 6/78 (7%)
Query: 120 GKHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLR 179
G HSHN+ S H + + H P + +H H H+
Sbjct: 336 GAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTH------RQHPHGHHPHGH 389
Query: 180 HHHRLHHHLDHNNTHHFH 197
H H H H H + HH H
Sbjct: 390 HPHGHHPHGHHPHGHHPH 407
Score = 30.8 bits (68), Expect = 5.4
Identities = 13/25 (52%), Positives = 15/25 (60%), Gaps = 3/25 (12%)
Query: 461 PHSQGGHDHS--HQHAHGHGHSHGH 483
PH+ H+H QH HGH H HGH
Sbjct: 366 PHAHHPHEHDTHRQHPHGH-HPHGH 389
Score = 30.8 bits (68), Expect = 5.4
Identities = 13/22 (59%), Positives = 13/22 (59%), Gaps = 2/22 (9%)
Query: 462 HSQGGHDHSHQHAHGHGHSHGH 483
H G H H H H HGH H HGH
Sbjct: 380 HPHGHHPHGH-HPHGH-HPHGH 399
Score = 30.8 bits (68), Expect = 5.4
Identities = 13/22 (59%), Positives = 13/22 (59%), Gaps = 2/22 (9%)
Query: 462 HSQGGHDHSHQHAHGHGHSHGH 483
H G H H H H HGH H HGH
Sbjct: 385 HPHGHHPHGH-HPHGH-HPHGH 404
>gi|21314720 Smad nuclear interacting protein [Homo sapiens]
Length = 396
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/114 (29%), Positives = 51/114 (44%), Gaps = 19/114 (16%)
Query: 207 GEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKSNENSEVITPGFPPNHDQGEQYEHNRV 266
G S P ++ N++ S VK+ K +R+ R+ E+ + H + + EH R
Sbjct: 86 GRRSKSPRSKRNRSPHHSTVKV-KQEREDHPRRGREDRQ---------HREPSEQEHRRA 135
Query: 267 HKPDRVHNPGHSHVHLP--ERNGHDPGRGHQDLDPDN------EGELRHTRKRE 312
DR + GHSH ER G G+G +D D N E E + R+RE
Sbjct: 136 RNSDRDRHRGHSHQRRTSNERPGSGQGQG-RDRDTQNLQAQEEEREFYNARRRE 188
Score = 33.9 bits (76), Expect = 0.64
Identities = 26/130 (20%), Positives = 41/130 (31%), Gaps = 2/130 (1%)
Query: 201 ITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKSNENSEVITPGFPPNHDQGEQ 260
+ ER P P P + + G + N V PP
Sbjct: 28 VVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRS--PPKKKNKAS 85
Query: 261 YEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPDNEGELRHTRKREAPHVKNNA 320
++ + R +P HS V + + P RG +D E H R R + ++
Sbjct: 86 GRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRG 145
Query: 321 IISLRKDLNE 330
R+ NE
Sbjct: 146 HSHQRRTSNE 155
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,963,046
Number of Sequences: 37866
Number of extensions: 1742009
Number of successful extensions: 10651
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 6808
Number of HSP's gapped (non-prelim): 2655
length of query: 831
length of database: 18,247,518
effective HSP length: 111
effective length of query: 720
effective length of database: 14,044,392
effective search space: 10111962240
effective search space used: 10111962240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.