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Search of human proteins with 187829452
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
(1235 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 2581 0.0
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 2567 0.0
gi|217416343 fibrosin-like 1 [Homo sapiens] 616 e-176
gi|187829485 autism susceptibility candidate 2 isoform 3 [Homo s... 441 e-123
gi|157364934 fibrosin [Homo sapiens] 239 1e-62
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 104 5e-22
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 104 5e-22
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 104 5e-22
gi|55750053 atrophin-1 [Homo sapiens] 88 6e-17
gi|55750041 atrophin-1 [Homo sapiens] 88 6e-17
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 79 2e-14
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 79 3e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 77 1e-13
gi|150417989 cyclin K isoform 1 [Homo sapiens] 73 1e-12
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 70 1e-11
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 69 4e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 8e-11
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 66 2e-10
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 65 3e-10
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 65 3e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is... 65 5e-10
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 64 9e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 64 1e-09
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 64 1e-09
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 64 1e-09
gi|54860079 nadrin isoform 1 [Homo sapiens] 63 2e-09
gi|153792074 proline rich 12 [Homo sapiens] 63 2e-09
gi|146134388 YLP motif containing 1 [Homo sapiens] 62 3e-09
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 61 8e-09
gi|55741677 SET domain containing 1A [Homo sapiens] 60 2e-08
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 2581 bits (6689), Expect = 0.0
Identities = 1235/1235 (100%), Positives = 1235/1235 (100%)
Query: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG
Sbjct: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
Query: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP
Sbjct: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
Query: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN
Sbjct: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
Query: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF 240
SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF
Sbjct: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF 240
Query: 241 NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP 300
NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP
Sbjct: 241 NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP 300
Query: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR 360
QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR
Sbjct: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR 360
Query: 361 PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP 420
PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP
Sbjct: 361 PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP 420
Query: 421 HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA 480
HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA
Sbjct: 421 HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA 480
Query: 481 GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ 540
GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ
Sbjct: 481 GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ 540
Query: 541 HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF 600
HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF
Sbjct: 541 HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF 600
Query: 601 GSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKP 660
GSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKP
Sbjct: 601 GSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKP 660
Query: 661 EFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPF 720
EFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPF
Sbjct: 661 EFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPF 720
Query: 721 NRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFP 780
NRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFP
Sbjct: 721 NRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFP 780
Query: 781 TPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVN 840
TPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVN
Sbjct: 781 TPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVN 840
Query: 841 ALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGH 900
ALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGH
Sbjct: 841 ALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGH 900
Query: 901 EGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKE 960
EGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKE
Sbjct: 901 EGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKE 960
Query: 961 ERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTR 1020
ERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTR
Sbjct: 961 ERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTR 1020
Query: 1021 MMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRL 1080
MMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRL
Sbjct: 1021 MMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRL 1080
Query: 1081 STPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEH 1140
STPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEH
Sbjct: 1081 STPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEH 1140
Query: 1141 TRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLI 1200
TRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLI
Sbjct: 1141 TRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLI 1200
Query: 1201 STLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR 1235
STLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR
Sbjct: 1201 STLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR 1235
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 2567 bits (6654), Expect = 0.0
Identities = 1235/1259 (98%), Positives = 1235/1259 (98%), Gaps = 24/1259 (1%)
Query: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG
Sbjct: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
Query: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP
Sbjct: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
Query: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN
Sbjct: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
Query: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF 240
SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF
Sbjct: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLF 240
Query: 241 NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP 300
NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP
Sbjct: 241 NTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP 300
Query: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR 360
QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR
Sbjct: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQR 360
Query: 361 PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP 420
PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP
Sbjct: 361 PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP 420
Query: 421 HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA 480
HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA
Sbjct: 421 HISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA 480
Query: 481 GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ 540
GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ
Sbjct: 481 GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ 540
Query: 541 HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF 600
HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF
Sbjct: 541 HTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPF 600
Query: 601 GSLQGAFQPK------------------------LTDPFRPMLRKPGKWCAMHVHIAWQI 636
GSLQGAFQPK LTDPFRPMLRKPGKWCAMHVHIAWQI
Sbjct: 601 GSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQI 660
Query: 637 YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP 696
YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP
Sbjct: 661 YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP 720
Query: 697 TGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDG 756
TGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDG
Sbjct: 721 TGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDG 780
Query: 757 PSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKD 816
PSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKD
Sbjct: 781 PSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKD 840
Query: 817 DKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES 876
DKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES
Sbjct: 841 DKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES 900
Query: 877 RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR 936
RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR
Sbjct: 901 RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR 960
Query: 937 EAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLA 996
EAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLA
Sbjct: 961 EAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLA 1020
Query: 997 SMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR 1056
SMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR
Sbjct: 1021 SMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR 1080
Query: 1057 ELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPR 1116
ELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPR
Sbjct: 1081 ELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPR 1140
Query: 1117 REHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPT 1176
REHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPT
Sbjct: 1141 REHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPT 1200
Query: 1177 AGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR 1235
AGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR
Sbjct: 1201 AGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR 1259
>gi|217416343 fibrosin-like 1 [Homo sapiens]
Length = 1045
Score = 616 bits (1588), Expect = e-176
Identities = 476/1299 (36%), Positives = 591/1299 (45%), Gaps = 331/1299 (25%)
Query: 10 LRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPP---SSA 66
+R RRSR+QRDR RR A A ++G G PP + A
Sbjct: 5 VRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGL----RGAPPRGAAPA 60
Query: 67 PSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKR 126
P RPPRR+RRES+S EE++IDGFA+ SF T EALEKD+ALKP ER EK + L KK R
Sbjct: 61 PRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPR 120
Query: 127 EALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSD 186
E+ T + S+ R P S ++ C K P ++ + RDSD
Sbjct: 121 ESETCPPAEPSENRR---PLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSD 177
Query: 187 SESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVN 246
+S +SSR+ LSDSSA + G GY CDS+S ++KAS SEKLF
Sbjct: 178 DDSV------LEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKAS-VGSEKLFA----- 225
Query: 247 KDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPI 306
P G E AGP VPK+SGLERS+E S + P P PCP
Sbjct: 226 --PGTDKGPALEKSEAKAGP-VPKVSGLERSRELSAESFL-PTASPAPHAAPCPG----- 276
Query: 307 PQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQS 366
PPP S P E PAP +PP PQ
Sbjct: 277 ---------------------------PPPGSRANPLVKKEP---PAPHRHTPQPPPPQ- 305
Query: 367 PTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHP 426
P LL ++P SL +++ L+ LS S S AP + H
Sbjct: 306 PRGLLPTHVPA--------SLGAFAGHSQAAANGLHGLSRSSS--------APLGLGKHV 349
Query: 427 SASPF---PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHP 483
S SP P +H L S H H MFA P LPPPP L + SL + GHP
Sbjct: 350 SLSPHGPGPHLSTSHLALRS------QAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHP 403
Query: 484 AGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQH-- 541
A + ++LRQELNTRFL + GASLGP LR EFHQHQH HQHTHQHTHQH
Sbjct: 404 A-----DHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQH 458
Query: 542 TFTPFPHAIPPTAIMPTPAPPMFDKYPTKVD-PFYRHS---LFHSYPPAVSGIPPMIPPT 597
TF PFP +PPT P APP FDKY K+D P++RHS F S+PPA+ G+P ++P
Sbjct: 459 TFAPFPAGLPPT---PPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHP 515
Query: 598 GPFGSLQGAFQPKLTDPFRPMLR------------------------------------- 620
GPFGSLQGAFQPK++DP+R +++
Sbjct: 516 GPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVA 575
Query: 621 -----------KPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGP 669
KPG+WCA+HV IAWQIY HQQK+K +MQ DPHKL+ G K + RPP P
Sbjct: 576 PAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIK-EMQLDPHKLEVGAKLDLFGRPPAP 634
Query: 670 SLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGL 729
+F H+P DLARP LF + GAAHP PFGP H +FL +PF+RPSTF GL
Sbjct: 635 GVFAGFHYPQDLARP--LFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGL 692
Query: 730 AAVGGNAFGGLGNPSVTPN-SMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKP 788
++ +AFGGLG+ ++ P S+F K+G SV +PHE WNRLHR PPSFP PPPW K
Sbjct: 693 GSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKS 752
Query: 789 GELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEK-RHSSHPSPAPVLPVNALGHTRS 847
+ ER ++ HDR+ D K+++ER+ +EK R S SPA GH S
Sbjct: 753 VDAERVSALTNHDREPD-------NGKEEQERDLLEKTRLLSRASPA-----TPAGHPVS 800
Query: 848 STEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGE 907
+ +E P ERE E + KE P K+ E
Sbjct: 801 G---LLLRAQSELGRSGAPAEREA------------EPRVKESRSPAKE----------E 835
Query: 908 EAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHD 967
AK AR P+ A P +VKVKEER ED
Sbjct: 836 AAKMPARASPPH------SKAAP-----------------------GDVKVKEERGED-- 864
Query: 968 LPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMG 1027
ASEPP + +HP PL +G
Sbjct: 865 ---------EASEPP----AGGLHPAPLQ-----------------------------LG 882
Query: 1028 ISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYE 1087
+ G ER P F W+P R L P R P S L
Sbjct: 883 L----GRERLGAPGFAWEPFRG-LELPRRAFPAAAPAP--------------GSAALLEP 923
Query: 1088 ADRSFRDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVH 1147
+R +RDREPH YS P R LR + E R +
Sbjct: 924 PERPYRDREPHGYS-------------PER----------------LRGELERARAPHLP 954
Query: 1148 PA--SLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPP-TAALSAPPPLISTLG 1204
PA +LDG L P L ++H+PR+SP A NGLL +TPP AAL APPPL+ T
Sbjct: 955 PAAPALDGAL------LPSLGALHFPRLSP-AALHNGLLARTPPAAAALGAPPPLV-TAA 1006
Query: 1205 GRPVSP----RRTTPLS----AEIRERPPSHTLKDIEAR 1235
G P P RTTPL E R+ PS ++EAR
Sbjct: 1007 GPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPPEVEAR 1045
>gi|187829485 autism susceptibility candidate 2 isoform 3 [Homo
sapiens]
Length = 266
Score = 441 bits (1134), Expect = e-123
Identities = 220/220 (100%), Positives = 220/220 (100%)
Query: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG
Sbjct: 1 MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNG 60
Query: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP
Sbjct: 61 KPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP 120
Query: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN
Sbjct: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
Query: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYF 220
SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYF
Sbjct: 181 SCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYF 220
>gi|157364934 fibrosin [Homo sapiens]
Length = 460
Score = 239 bits (610), Expect = 1e-62
Identities = 124/297 (41%), Positives = 180/297 (60%), Gaps = 39/297 (13%)
Query: 563 MFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDP-------- 614
MF+KYP K++ +RH+ + ++PPAV G+PP +PP FGSLQGAFQPK T+P
Sbjct: 1 MFEKYPGKMEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPKSTNPELPPRLGP 60
Query: 615 ---------------FRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLK 659
FRP LRKPGKWCAMHV +A+ I HQ+K M+ D HKLDF +
Sbjct: 61 VPSGLSQKGTQIPDHFRPPLRKPGKWCAMHVRVAYMILRHQEK----MKGDSHKLDF--R 114
Query: 660 PEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPF-GPPPHHSNFLNPAAHLE 718
+ L PGP +GA+ +L+ P++LF+A GA H PF P H FL+P+ H++
Sbjct: 115 NDLLPCLPGP--YGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHID 172
Query: 719 PFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSV-QNFSNPHEPWNRLHRTPP 777
PF RP++F LAA+ AFGGLG+P+ ++F K+ P F++P +PW RLHR+P
Sbjct: 173 PFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPL 232
Query: 778 SFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPA 834
+FP W++P E R+ + D++R V++R+ S++K++K+R+ R SPA
Sbjct: 233 TFPA---WVRPPEAARTPGS---DKERPVERREPSITKEEKDRDLPFSRPQLRVSPA 283
Score = 36.2 bits (82), Expect = 0.20
Identities = 28/71 (39%), Positives = 33/71 (46%), Gaps = 13/71 (18%)
Query: 1142 RLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLIS 1201
RL+ + PA HP L + P P A LL+KTPP A L APPPL+
Sbjct: 394 RLYGLEPA-------HPLLYSRLAP----PPPPAAAPGTPHLLSKTPPGALLGAPPPLVP 442
Query: 1202 TLGGRPVSPRR 1212
RP SP R
Sbjct: 443 --APRPSSPPR 451
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 104 bits (260), Expect = 5e-22
Identities = 242/1102 (21%), Positives = 347/1102 (31%), Gaps = 308/1102 (27%)
Query: 166 KKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSR----ERLSDSSAPSSLGTGYFC 221
KK K +++ E + +++ R+SS+ + +S ++PS G G
Sbjct: 76 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESS 134
Query: 222 DSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS 281
DS S +E +SD P+ QD P I + ++ S
Sbjct: 135 DSRSVNDEGSSD-----------------------PKDIDQDNRSTSPSIPSPQDNESDS 171
Query: 282 QDCCKEPIFE--PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST 339
++ + + P L+ P P P PQL P P P T PPQ P ++
Sbjct: 172 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA---TAVPPQGSPTAS 228
Query: 340 QPPQGP-------PEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLS 392
Q P P P +Q AP QRPP P P HPS QPL+
Sbjct: 229 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPP------------HPSPHPPLQPLT 276
Query: 393 AYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPA 452
S+ + S P+ QP H P P SL P LQ P
Sbjct: 277 G-----------SAGQPSAPSHAQPPL-----HGQGPPGPHSL-------QAGPLLQHPG 313
Query: 453 HSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGA 512
PP PP + G + PA + L+ + L SQ R
Sbjct: 314 ---------PPQPFGLPPQASQGQAPLGTSPAAAY--PHTSLQLPASQSALQSQQPPREQ 362
Query: 513 SLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPP--TAIMPTPAPPMFDKYPTK 570
L P P PH PP T I PAP
Sbjct: 363 PLPPAPLA-------------------------MPHIKPPPTTPIPQLPAPQA------- 390
Query: 571 VDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHV 630
H +PP +SG P F P P L+ H
Sbjct: 391 ----------HKHPPHLSGPSP--------------FSMNANLPPPPALKPLSSLSTHHP 426
Query: 631 HIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSA 690
A H ++ QS P P ++PPG + + P P+ L
Sbjct: 427 PSA-----HPPPLQLMPQSQP-------LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 474
Query: 691 AG----AAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVT 746
A A HP P GPPP + P PST T A G +A + +
Sbjct: 475 APQPPFAQHPF-VPGGPPP-----------ITPPTCPSTSTPPAGPGTSAQPPCSGAAAS 522
Query: 747 PNSMFGHKDGP---------SVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASA 797
S+ G P ++ + P P PP P+P P + S SA
Sbjct: 523 GGSIAGGSSCPLPTVQIKEEALDDAEEPESP-----PPPPRSPSPEPTVVDTPSHASQSA 577
Query: 798 AAHDRDRDVDKRDSSVSKDD-------------KERESVEKRHSSHPSPAPVLPVNALGH 844
+ + +D+ +S ++ D K E++EK
Sbjct: 578 RFY---KHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK------------------- 615
Query: 845 TRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHL--PEKDGHGHEG 902
+ EQ +EK+K +ERER+ + A A EG L P+ G GH
Sbjct: 616 AKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMR 675
Query: 903 RAAGEEAKQLARVP-------------SPYVRTPVVESARPNSTSSREAEPRKGEPAYEN 949
+ +A VP S Y R V+ N P AY
Sbjct: 676 PSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHM 735
Query: 950 P-----------KKSSEVKVKEERKEDHDL-----------PPEAPQTHRASEP------ 981
P ++ E +++E + +L PPE H A+ P
Sbjct: 736 PGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFAR 795
Query: 982 ------PP---PNSSSSVHPG--PLASMPMTVGVTGIHP-MNSISSLDRTRMMTPFMGIS 1029
PP P+ +S HPG PL + + + P M+ L R+ M +
Sbjct: 796 HSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERM--A 853
Query: 1030 PLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEAD 1089
L F+ P + L +H++DPL + P+H L P
Sbjct: 854 SLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQG---SAGPVHPLVDP------ 904
Query: 1090 RSFRDREPH--DYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVH 1147
PH + + +PL P EHE MLR H + +
Sbjct: 905 ---LTAGPHLARFPYPPGTLPNPLLGQPPHEHE------------MLR----HPVFGTPY 945
Query: 1148 PASLDGHLPHPSLITPGLPSMH 1169
P L G +P P L +MH
Sbjct: 946 PRDLPGAIPPPMSAAHQLQAMH 967
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 104 bits (260), Expect = 5e-22
Identities = 242/1102 (21%), Positives = 347/1102 (31%), Gaps = 308/1102 (27%)
Query: 166 KKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSR----ERLSDSSAPSSLGTGYFC 221
KK K +++ E + +++ R+SS+ + +S ++PS G G
Sbjct: 630 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESS 688
Query: 222 DSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS 281
DS S +E +SD P+ QD P I + ++ S
Sbjct: 689 DSRSVNDEGSSD-----------------------PKDIDQDNRSTSPSIPSPQDNESDS 725
Query: 282 QDCCKEPIFE--PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST 339
++ + + P L+ P P P PQL P P P T PPQ P ++
Sbjct: 726 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA---TAVPPQGSPTAS 782
Query: 340 QPPQGP-------PEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLS 392
Q P P P +Q AP QRPP P P HPS QPL+
Sbjct: 783 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPP------------HPSPHPPLQPLT 830
Query: 393 AYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPA 452
S+ + S P+ QP H P P SL P LQ P
Sbjct: 831 G-----------SAGQPSAPSHAQPPL-----HGQGPPGPHSL-------QAGPLLQHPG 867
Query: 453 HSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGA 512
PP PP + G + PA + L+ + L SQ R
Sbjct: 868 ---------PPQPFGLPPQASQGQAPLGTSPAAAY--PHTSLQLPASQSALQSQQPPREQ 916
Query: 513 SLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPP--TAIMPTPAPPMFDKYPTK 570
L P P PH PP T I PAP
Sbjct: 917 PLPPAPLA-------------------------MPHIKPPPTTPIPQLPAPQA------- 944
Query: 571 VDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHV 630
H +PP +SG P F P P L+ H
Sbjct: 945 ----------HKHPPHLSGPSP--------------FSMNANLPPPPALKPLSSLSTHHP 980
Query: 631 HIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSA 690
A H ++ QS P P ++PPG + + P P+ L
Sbjct: 981 PSA-----HPPPLQLMPQSQP-------LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028
Query: 691 AG----AAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVT 746
A A HP P GPPP + P PST T A G +A + +
Sbjct: 1029 APQPPFAQHPF-VPGGPPP-----------ITPPTCPSTSTPPAGPGTSAQPPCSGAAAS 1076
Query: 747 PNSMFGHKDGP---------SVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASA 797
S+ G P ++ + P P PP P+P P + S SA
Sbjct: 1077 GGSIAGGSSCPLPTVQIKEEALDDAEEPESP-----PPPPRSPSPEPTVVDTPSHASQSA 1131
Query: 798 AAHDRDRDVDKRDSSVSKDD-------------KERESVEKRHSSHPSPAPVLPVNALGH 844
+ + +D+ +S ++ D K E++EK
Sbjct: 1132 RFY---KHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK------------------- 1169
Query: 845 TRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHL--PEKDGHGHEG 902
+ EQ +EK+K +ERER+ + A A EG L P+ G GH
Sbjct: 1170 AKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMR 1229
Query: 903 RAAGEEAKQLARVP-------------SPYVRTPVVESARPNSTSSREAEPRKGEPAYEN 949
+ +A VP S Y R V+ N P AY
Sbjct: 1230 PSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHM 1289
Query: 950 P-----------KKSSEVKVKEERKEDHDL-----------PPEAPQTHRASEP------ 981
P ++ E +++E + +L PPE H A+ P
Sbjct: 1290 PGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFAR 1349
Query: 982 ------PP---PNSSSSVHPG--PLASMPMTVGVTGIHP-MNSISSLDRTRMMTPFMGIS 1029
PP P+ +S HPG PL + + + P M+ L R+ M +
Sbjct: 1350 HSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERM--A 1407
Query: 1030 PLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEAD 1089
L F+ P + L +H++DPL + P+H L P
Sbjct: 1408 SLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQG---SAGPVHPLVDP------ 1458
Query: 1090 RSFRDREPH--DYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVH 1147
PH + + +PL P EHE MLR H + +
Sbjct: 1459 ---LTAGPHLARFPYPPGTLPNPLLGQPPHEHE------------MLR----HPVFGTPY 1499
Query: 1148 PASLDGHLPHPSLITPGLPSMH 1169
P L G +P P L +MH
Sbjct: 1500 PRDLPGAIPPPMSAAHQLQAMH 1521
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 104 bits (260), Expect = 5e-22
Identities = 242/1102 (21%), Positives = 347/1102 (31%), Gaps = 308/1102 (27%)
Query: 166 KKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSR----ERLSDSSAPSSLGTGYFC 221
KK K +++ E + +++ R+SS+ + +S ++PS G G
Sbjct: 630 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESS 688
Query: 222 DSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS 281
DS S +E +SD P+ QD P I + ++ S
Sbjct: 689 DSRSVNDEGSSD-----------------------PKDIDQDNRSTSPSIPSPQDNESDS 725
Query: 282 QDCCKEPIFE--PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST 339
++ + + P L+ P P P PQL P P P T PPQ P ++
Sbjct: 726 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA---TAVPPQGSPTAS 782
Query: 340 QPPQGP-------PEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLS 392
Q P P P +Q AP QRPP P P HPS QPL+
Sbjct: 783 QAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPP------------HPSPHPPLQPLT 830
Query: 393 AYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPA 452
S+ + S P+ QP H P P SL P LQ P
Sbjct: 831 G-----------SAGQPSAPSHAQPPL-----HGQGPPGPHSL-------QAGPLLQHPG 867
Query: 453 HSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGA 512
PP PP + G + PA + L+ + L SQ R
Sbjct: 868 ---------PPQPFGLPPQASQGQAPLGTSPAAAY--PHTSLQLPASQSALQSQQPPREQ 916
Query: 513 SLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPP--TAIMPTPAPPMFDKYPTK 570
L P P PH PP T I PAP
Sbjct: 917 PLPPAPLA-------------------------MPHIKPPPTTPIPQLPAPQA------- 944
Query: 571 VDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHV 630
H +PP +SG P F P P L+ H
Sbjct: 945 ----------HKHPPHLSGPSP--------------FSMNANLPPPPALKPLSSLSTHHP 980
Query: 631 HIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSA 690
A H ++ QS P P ++PPG + + P P+ L
Sbjct: 981 PSA-----HPPPLQLMPQSQP-------LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028
Query: 691 AG----AAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVT 746
A A HP P GPPP + P PST T A G +A + +
Sbjct: 1029 APQPPFAQHPF-VPGGPPP-----------ITPPTCPSTSTPPAGPGTSAQPPCSGAAAS 1076
Query: 747 PNSMFGHKDGP---------SVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASA 797
S+ G P ++ + P P PP P+P P + S SA
Sbjct: 1077 GGSIAGGSSCPLPTVQIKEEALDDAEEPESP-----PPPPRSPSPEPTVVDTPSHASQSA 1131
Query: 798 AAHDRDRDVDKRDSSVSKDD-------------KERESVEKRHSSHPSPAPVLPVNALGH 844
+ + +D+ +S ++ D K E++EK
Sbjct: 1132 RFY---KHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK------------------- 1169
Query: 845 TRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHL--PEKDGHGHEG 902
+ EQ +EK+K +ERER+ + A A EG L P+ G GH
Sbjct: 1170 AKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMR 1229
Query: 903 RAAGEEAKQLARVP-------------SPYVRTPVVESARPNSTSSREAEPRKGEPAYEN 949
+ +A VP S Y R V+ N P AY
Sbjct: 1230 PSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHM 1289
Query: 950 P-----------KKSSEVKVKEERKEDHDL-----------PPEAPQTHRASEP------ 981
P ++ E +++E + +L PPE H A+ P
Sbjct: 1290 PGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFAR 1349
Query: 982 ------PP---PNSSSSVHPG--PLASMPMTVGVTGIHP-MNSISSLDRTRMMTPFMGIS 1029
PP P+ +S HPG PL + + + P M+ L R+ M +
Sbjct: 1350 HSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERM--A 1407
Query: 1030 PLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEAD 1089
L F+ P + L +H++DPL + P+H L P
Sbjct: 1408 SLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQG---SAGPVHPLVDP------ 1458
Query: 1090 RSFRDREPH--DYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVH 1147
PH + + +PL P EHE MLR H + +
Sbjct: 1459 ---LTAGPHLARFPYPPGTLPNPLLGQPPHEHE------------MLR----HPVFGTPY 1499
Query: 1148 PASLDGHLPHPSLITPGLPSMH 1169
P L G +P P L +MH
Sbjct: 1500 PRDLPGAIPPPMSAAHQLQAMH 1521
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 87.8 bits (216), Expect = 6e-17
Identities = 228/968 (23%), Positives = 313/968 (32%), Gaps = 245/968 (25%)
Query: 300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQG---PPEAQ------L 350
P P P P L P P L A PP L QP G P A L
Sbjct: 286 PSAPPPANFPHVTPNL---PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGL 342
Query: 351 QPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSS 410
P P+ P P S LPP + A + P S+ +SSS + +S SSS SS
Sbjct: 343 PPGPEKGPTLAPSPHS--------LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS 394
Query: 411 TPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTL------QPPAHSHH--PNMFAP 462
SASPFP S S HSF P QPP ++ P+
Sbjct: 395 ----------------SASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVW 438
Query: 463 PTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRT 522
PPPPP HP S GA P + T
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFPPST--------------------GAQSTAHPPVST 478
Query: 523 EFHQHQHQHQHTHQHTHQHTFTPFPHAI---PPTAIMPTPAP--PMFDKYPTKVDPFYRH 577
H HQ Q Q Q Q H PP P P +P + P
Sbjct: 479 HHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSL-- 536
Query: 578 SLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLR-KPGKWCAMHVHIAWQI 636
YPP + +PP P + S G P ++ G + H
Sbjct: 537 GSLRPYPPGPAHLPP--PHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSH------- 587
Query: 637 YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP 696
+ Q P+ PP P++ + L+ +++ A +
Sbjct: 588 ----PSPSQGPQGAPYPF-----------PPVPTVTTS---SATLSTVIATVASSPAGYK 629
Query: 697 TGTPFGPPPHHSNFLNPAAH-------LEPFNRPS-------TFTGLAAVGGNAFGGLGN 742
T +P GPPP+ +P A+ +P + PS + G + G G+
Sbjct: 630 TASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS 689
Query: 743 PSVTPNSM---------------FGHKDGPSVQNFSNPHEPWNRLHRTPPS------FPT 781
P+V P + GP + EP + TP S P+
Sbjct: 690 PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEE-YETPESPVPPARSPS 748
Query: 782 PPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNA 841
PPP K ++ AS +A ++ +D+ +S ++ D +E + V V
Sbjct: 749 PPP--KVVDVPSHASQSAR-FNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRR 805
Query: 842 LGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLP-EKDGHGH 900
R+ E+ R RE+++ KERER E ++L A+EG P E G
Sbjct: 806 EAEQRAREEKER------EREREREKERER---EKERELERSVKLAQEGRAPVECPSLGP 856
Query: 901 -EGRAAGEEAKQLARVP------SPYVRTPVVESARPNSTSSRE-----------AEP-- 940
R E +A VP +P +RT + E ARP+ S +P
Sbjct: 857 VPHRPPFEPGSAVATVPPYLGPDTPALRT-LSEYARPHVMSPGNRNHPFYVPLGAVDPGL 915
Query: 941 -RKGEPAYENPKKSSEVKVKEERKED--HDLPPEAPQTHRASEP----PPPNSSSSVHPG 993
PA + ++ + +E R+ D L P EP P P G
Sbjct: 916 LGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHG 975
Query: 994 PLASMPMTVGVTGIHPM---NSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDP 1050
LA P G G+HP S+ L+R R+ L G P+ D
Sbjct: 976 GLALQP---GPPGLHPFPFHPSLGPLERERL--------ALAAG-----PALRPDM---- 1015
Query: 1051 LRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHP 1110
Y E R R L NDPL RL + PH + H H H H
Sbjct: 1016 ---SYAERLAAERQHAERVAALGNDPLARLQMLNV----------TPHHHQHSHIHSH-- 1060
Query: 1111 LSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHY 1170
LH+ ++D H SVHP LI P H
Sbjct: 1061 --------------------LHLHQQDAIHAASASVHP-----------LIDPLASGSHL 1089
Query: 1171 PRISPTAG 1178
RI AG
Sbjct: 1090 TRIPYPAG 1097
Score = 84.0 bits (206), Expect = 8e-16
Identities = 216/1022 (21%), Positives = 354/1022 (34%), Gaps = 145/1022 (14%)
Query: 152 RENDRNLCQHLGKRKKMPKALRQLKP-GQNSCRDSDSESASGESKGFHRSSSRERLSDSS 210
R+N ++ G++K+ P +L+ G+ S + S+ G+++ +++ + R+ ++S
Sbjct: 4 RQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEAS 63
Query: 211 APSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLP------------- 257
P G + S+ E + ++A + + + +L
Sbjct: 64 TPKVNKQGR-SEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPR 122
Query: 258 --EHDSQDAGPIVPKISGLERSQEKSQDCCKEPI--FEPVVLKDPCPQVAQPIP-QPQTE 312
+ D++ P + +E + S + P + P L P PQ P QP+
Sbjct: 123 DIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEAS 182
Query: 313 PQLRAPSPDPDLVQRTEAPPQPPPLST--QPPQG--PPEAQLQPAPQPQVQRPPRPQSPT 368
+ P P + P PP S Q P G PP QL P V P P P
Sbjct: 183 FE-----PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGP-PMGP- 235
Query: 369 QLLHQNLPPVQAHPSAQSLSQPLSA--YNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHP 426
+ +A S+ P + + ++ SS S P P P +
Sbjct: 236 ----------KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNL 285
Query: 427 SASPFPLSLPNHSPLHSFTPTLQP--PAHSHHPNMFAPPTA--LPPPPPLTSGSLQVAGH 482
++P P + P+ +P P L+P A + P + A P LP P + G + G
Sbjct: 286 PSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQG---MGGL 342
Query: 483 PAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQH--QHTHQHTHQ 540
P G ++ T + S +S P P +R + + +
Sbjct: 343 PPGP---------EKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSS 393
Query: 541 HTFTPFP--HAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTG 598
+ +PFP A+P P PP + P Y S G PP PP
Sbjct: 394 SSASPFPASQALPS---YPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP--PP-- 446
Query: 599 PFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGL 658
P+G L A PF P G H ++ +HHQQ+ ++Q Q +
Sbjct: 447 PYGRLL-ANSNAHPGPFPP---STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ-QQ 501
Query: 659 KPEFLSRPPGPSLF------GAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHS-NFL 711
+ S PP P F G+ HH H A +L S +P G PPPH ++
Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSL--RPYPPGPAHLPPPHSQVSYS 559
Query: 712 NPAAHLEPFNRPSTFTGLAAVG--------------GNAFGGLGNPSVTPNS------MF 751
+ P + S + + G G + P+VT +S +
Sbjct: 560 QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIA 619
Query: 752 GHKDGPSVQNFSNP--HEPWNRLHRTPPSFPT-PPPWLKPGELERSASAAAHDRDRDVDK 808
P+ ++P P+ + +P ++ T PP KPG +
Sbjct: 620 TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPP 679
Query: 809 RDSSVSKDDKERESVEKRHSSHPSPAPVLP----VNALGHTRSSTEQIRAHLNTEAREKD 864
K + PS P LP A G S+T QI+ E +
Sbjct: 680 AGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSAT-QIKQEPAEEYETPE 738
Query: 865 KPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGE------EAKQLARVPSP 918
P R S K + H ++ + G A + E +LA+ +
Sbjct: 739 SPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRAD 798
Query: 919 Y---VRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQT 975
VR + AR RE E K + + VK+ +E + + P P
Sbjct: 799 LVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVP 858
Query: 976 HRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPL---- 1031
HR PP S+V A++P +G + ++S R +M+P P
Sbjct: 859 HR----PPFEPGSAV-----ATVPPYLG-PDTPALRTLSEYARPHVMSPGNRNHPFYVPL 908
Query: 1032 ----PGGERFPYPS-FHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRN---DPLHRLSTP 1083
PG + P+ + DP RE D+ RD L F ++ +PLH + P
Sbjct: 909 GAVDPGLLGYNVPALYSSDPAAREREREARERDL--RDRLKPGFEVKPSELEPLHGVPGP 966
Query: 1084 RL 1085
L
Sbjct: 967 GL 968
Score = 50.8 bits (120), Expect = 8e-06
Identities = 81/296 (27%), Positives = 102/296 (34%), Gaps = 56/296 (18%)
Query: 324 LVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPT----QLLHQNLPPVQ 379
L Q AP + P L P + P E A P P P T H P +
Sbjct: 841 LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNR 900
Query: 380 AHPSAQSLSQPLSAYNSSSLSLN--SLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPN 437
HP PL A + L N +L SS + + + A F +
Sbjct: 901 NHP----FYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSE 956
Query: 438 HSPLHSFT-PTLQP-PAHSHHPNMFAPPTALPPP-----PPLTSGSLQVAGHPAGSTYSE 490
PLH P L P P H PP P P PL L +A PA
Sbjct: 957 LEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPA------ 1010
Query: 491 QDILRQELN--TRFLAS-QSADRGASLGPPPYLRTEF-----HQHQHQHQHTHQHTHQ-- 540
LR +++ R A Q A+R A+LG P R + H HQH H H+H H HQ
Sbjct: 1011 ---LRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQD 1067
Query: 541 --HTFTPFPH-------------AIP-PTAIMPTPAPPMFDKYPTKVDPFYRHSLF 580
H + H IP P +P P P +P + RH LF
Sbjct: 1068 AIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNPLLP----HPLHENEVLRHQLF 1119
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 87.8 bits (216), Expect = 6e-17
Identities = 228/968 (23%), Positives = 313/968 (32%), Gaps = 245/968 (25%)
Query: 300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQG---PPEAQ------L 350
P P P P L P P L A PP L QP G P A L
Sbjct: 286 PSAPPPANFPHVTPNL---PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGL 342
Query: 351 QPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSS 410
P P+ P P S LPP + A + P S+ +SSS + +S SSS SS
Sbjct: 343 PPGPEKGPTLAPSPHS--------LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS 394
Query: 411 TPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTL------QPPAHSHH--PNMFAP 462
SASPFP S S HSF P QPP ++ P+
Sbjct: 395 ----------------SASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVW 438
Query: 463 PTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRT 522
PPPPP HP S GA P + T
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFPPST--------------------GAQSTAHPPVST 478
Query: 523 EFHQHQHQHQHTHQHTHQHTFTPFPHAI---PPTAIMPTPAP--PMFDKYPTKVDPFYRH 577
H HQ Q Q Q Q H PP P P +P + P
Sbjct: 479 HHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSL-- 536
Query: 578 SLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLR-KPGKWCAMHVHIAWQI 636
YPP + +PP P + S G P ++ G + H
Sbjct: 537 GSLRPYPPGPAHLPP--PHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSH------- 587
Query: 637 YHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHP 696
+ Q P+ PP P++ + L+ +++ A +
Sbjct: 588 ----PSPSQGPQGAPYPF-----------PPVPTVTTS---SATLSTVIATVASSPAGYK 629
Query: 697 TGTPFGPPPHHSNFLNPAAH-------LEPFNRPS-------TFTGLAAVGGNAFGGLGN 742
T +P GPPP+ +P A+ +P + PS + G + G G+
Sbjct: 630 TASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS 689
Query: 743 PSVTPNSM---------------FGHKDGPSVQNFSNPHEPWNRLHRTPPS------FPT 781
P+V P + GP + EP + TP S P+
Sbjct: 690 PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEE-YETPESPVPPARSPS 748
Query: 782 PPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNA 841
PPP K ++ AS +A ++ +D+ +S ++ D +E + V V
Sbjct: 749 PPP--KVVDVPSHASQSAR-FNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRR 805
Query: 842 LGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLP-EKDGHGH 900
R+ E+ R RE+++ KERER E ++L A+EG P E G
Sbjct: 806 EAEQRAREEKER------EREREREKERER---EKERELERSVKLAQEGRAPVECPSLGP 856
Query: 901 -EGRAAGEEAKQLARVP------SPYVRTPVVESARPNSTSSRE-----------AEP-- 940
R E +A VP +P +RT + E ARP+ S +P
Sbjct: 857 VPHRPPFEPGSAVATVPPYLGPDTPALRT-LSEYARPHVMSPGNRNHPFYVPLGAVDPGL 915
Query: 941 -RKGEPAYENPKKSSEVKVKEERKED--HDLPPEAPQTHRASEP----PPPNSSSSVHPG 993
PA + ++ + +E R+ D L P EP P P G
Sbjct: 916 LGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHG 975
Query: 994 PLASMPMTVGVTGIHPM---NSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDP 1050
LA P G G+HP S+ L+R R+ L G P+ D
Sbjct: 976 GLALQP---GPPGLHPFPFHPSLGPLERERL--------ALAAG-----PALRPDM---- 1015
Query: 1051 LRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHP 1110
Y E R R L NDPL RL + PH + H H H H
Sbjct: 1016 ---SYAERLAAERQHAERVAALGNDPLARLQMLNV----------TPHHHQHSHIHSH-- 1060
Query: 1111 LSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHY 1170
LH+ ++D H SVHP LI P H
Sbjct: 1061 --------------------LHLHQQDAIHAASASVHP-----------LIDPLASGSHL 1089
Query: 1171 PRISPTAG 1178
RI AG
Sbjct: 1090 TRIPYPAG 1097
Score = 84.0 bits (206), Expect = 8e-16
Identities = 216/1022 (21%), Positives = 354/1022 (34%), Gaps = 145/1022 (14%)
Query: 152 RENDRNLCQHLGKRKKMPKALRQLKP-GQNSCRDSDSESASGESKGFHRSSSRERLSDSS 210
R+N ++ G++K+ P +L+ G+ S + S+ G+++ +++ + R+ ++S
Sbjct: 4 RQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEAS 63
Query: 211 APSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLP------------- 257
P G + S+ E + ++A + + + +L
Sbjct: 64 TPKVNKQGR-SEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPR 122
Query: 258 --EHDSQDAGPIVPKISGLERSQEKSQDCCKEPI--FEPVVLKDPCPQVAQPIP-QPQTE 312
+ D++ P + +E + S + P + P L P PQ P QP+
Sbjct: 123 DIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEAS 182
Query: 313 PQLRAPSPDPDLVQRTEAPPQPPPLST--QPPQG--PPEAQLQPAPQPQVQRPPRPQSPT 368
+ P P + P PP S Q P G PP QL P V P P P
Sbjct: 183 FE-----PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGP-PMGP- 235
Query: 369 QLLHQNLPPVQAHPSAQSLSQPLSA--YNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHP 426
+ +A S+ P + + ++ SS S P P P +
Sbjct: 236 ----------KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNL 285
Query: 427 SASPFPLSLPNHSPLHSFTPTLQP--PAHSHHPNMFAPPTA--LPPPPPLTSGSLQVAGH 482
++P P + P+ +P P L+P A + P + A P LP P + G + G
Sbjct: 286 PSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQG---MGGL 342
Query: 483 PAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQH--QHTHQHTHQ 540
P G ++ T + S +S P P +R + + +
Sbjct: 343 PPGP---------EKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSS 393
Query: 541 HTFTPFP--HAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTG 598
+ +PFP A+P P PP + P Y S G PP PP
Sbjct: 394 SSASPFPASQALPS---YPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP--PP-- 446
Query: 599 PFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGL 658
P+G L A PF P G H ++ +HHQQ+ ++Q Q +
Sbjct: 447 PYGRLL-ANSNAHPGPFPP---STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ-QQ 501
Query: 659 KPEFLSRPPGPSLF------GAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHS-NFL 711
+ S PP P F G+ HH H A +L S +P G PPPH ++
Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSL--RPYPPGPAHLPPPHSQVSYS 559
Query: 712 NPAAHLEPFNRPSTFTGLAAVG--------------GNAFGGLGNPSVTPNS------MF 751
+ P + S + + G G + P+VT +S +
Sbjct: 560 QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIA 619
Query: 752 GHKDGPSVQNFSNP--HEPWNRLHRTPPSFPT-PPPWLKPGELERSASAAAHDRDRDVDK 808
P+ ++P P+ + +P ++ T PP KPG +
Sbjct: 620 TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPP 679
Query: 809 RDSSVSKDDKERESVEKRHSSHPSPAPVLP----VNALGHTRSSTEQIRAHLNTEAREKD 864
K + PS P LP A G S+T QI+ E +
Sbjct: 680 AGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSAT-QIKQEPAEEYETPE 738
Query: 865 KPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGE------EAKQLARVPSP 918
P R S K + H ++ + G A + E +LA+ +
Sbjct: 739 SPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRAD 798
Query: 919 Y---VRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQT 975
VR + AR RE E K + + VK+ +E + + P P
Sbjct: 799 LVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVP 858
Query: 976 HRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPL---- 1031
HR PP S+V A++P +G + ++S R +M+P P
Sbjct: 859 HR----PPFEPGSAV-----ATVPPYLG-PDTPALRTLSEYARPHVMSPGNRNHPFYVPL 908
Query: 1032 ----PGGERFPYPS-FHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRN---DPLHRLSTP 1083
PG + P+ + DP RE D+ RD L F ++ +PLH + P
Sbjct: 909 GAVDPGLLGYNVPALYSSDPAAREREREARERDL--RDRLKPGFEVKPSELEPLHGVPGP 966
Query: 1084 RL 1085
L
Sbjct: 967 GL 968
Score = 50.8 bits (120), Expect = 8e-06
Identities = 81/296 (27%), Positives = 102/296 (34%), Gaps = 56/296 (18%)
Query: 324 LVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPT----QLLHQNLPPVQ 379
L Q AP + P L P + P E A P P P T H P +
Sbjct: 841 LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNR 900
Query: 380 AHPSAQSLSQPLSAYNSSSLSLN--SLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPN 437
HP PL A + L N +L SS + + + A F +
Sbjct: 901 NHP----FYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSE 956
Query: 438 HSPLHSFT-PTLQP-PAHSHHPNMFAPPTALPPP-----PPLTSGSLQVAGHPAGSTYSE 490
PLH P L P P H PP P P PL L +A PA
Sbjct: 957 LEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPA------ 1010
Query: 491 QDILRQELN--TRFLAS-QSADRGASLGPPPYLRTEF-----HQHQHQHQHTHQHTHQ-- 540
LR +++ R A Q A+R A+LG P R + H HQH H H+H H HQ
Sbjct: 1011 ---LRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQD 1067
Query: 541 --HTFTPFPH-------------AIP-PTAIMPTPAPPMFDKYPTKVDPFYRHSLF 580
H + H IP P +P P P +P + RH LF
Sbjct: 1068 AIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNPLLP----HPLHENEVLRHQLF 1119
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 79.3 bits (194), Expect = 2e-14
Identities = 136/564 (24%), Positives = 176/564 (31%), Gaps = 142/564 (25%)
Query: 257 PEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLR 316
P + A P + L P+ P + PCP P P L
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA---PCPLQAPPSPLT 577
Query: 317 APSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLP 376
P P+ T P PP L++ P QG P L P P Q PP LP
Sbjct: 578 TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP---------XLALP 628
Query: 377 PVQAHPSAQSLSQPLSAY-NSSSLSLNSLSSSRSSTPAKTQPAPP-HISHHPSASPFPLS 434
P+QA PS + S PLS S + N+L+ P P+PP P ASP P+S
Sbjct: 629 PLQAPPSPPA-SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVS 686
Query: 435 ----LPNHSPLHSFTPTLQ-PPAHSHHPNMFAPPTALPP---PPPLTSGSLQVAGHPAGS 486
P+ +P P LQ PP+ P M P+A PP PPPL + LQV P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPM--SPSATPPPQAPPPLAAPPLQVPPSPPA- 743
Query: 487 TYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPF 546
S S PPP + P
Sbjct: 744 --------------------SPPMSPSATPPPRV------------------------PP 759
Query: 547 PHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFG-SLQG 605
A PP + P+P P P P PPA++ P P+ P Q
Sbjct: 760 LLAAPPLQVPPSP-PASLPMSPLAKPP-------PQAPPALATPPLQALPSPPASFPGQA 811
Query: 606 AFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSR 665
F P + P P+ P Q+ P L L
Sbjct: 812 PFSPSASLPMSPLATPP------------------------PQAPP-----VLAAPLLQV 842
Query: 666 PPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPST 725
PP P + P P S +G GPPP P PS+
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP------------PPSRSPSS 890
Query: 726 FTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNP----------HEPWNR---- 771
G + G + + TP + G+ GP ++P W+R
Sbjct: 891 ----TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 946
Query: 772 --LHRTPPSFPTP-PPWLKPGELE 792
R P P P PP PG +
Sbjct: 947 PLAFRGAPGAPLPWPPATGPGSAD 970
Score = 71.6 bits (174), Expect = 4e-12
Identities = 172/725 (23%), Positives = 240/725 (33%), Gaps = 102/725 (14%)
Query: 27 RGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEED 86
R L A G GGA + A + S + P S P+ R R ++TS
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPV 114
Query: 87 IIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPH 146
G A + +K + + +E V + + KR AL+ G + P
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKAT-EAPKRSALSAGARRDTSGPTPGTPS 173
Query: 147 HYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERL 206
+ R R +G + P A + +P R S S SAS S ++R R
Sbjct: 174 PAMARRS--RAAGTEVGLPRPAPSA--RPRPPTEGPRKSVS-SASEHSTTEPSPAARRRP 228
Query: 207 SDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGP 266
S + S + A S + G P H SQ
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSAR-------------GTPRAPAHPSQ---- 271
Query: 267 IVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQV----AQPIPQPQTEPQLRAPSPDP 322
PK GL+ + P P KD P + + P+ P P P P
Sbjct: 272 --PKPKGLQ--------ALRPPQVTPP-RKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320
Query: 323 DLVQRTEAP---PQPPPLST------QPPQGPPEAQLQPAP-------------QPQVQR 360
D T P P PPL+T P PP Q P+P P +Q
Sbjct: 321 DNAA-TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA 379
Query: 361 PPRPQS--PTQLLHQ-NLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQ- 416
PP Q+ P Q+ H P +QA PS +LS + + S +L + S + +P +TQ
Sbjct: 380 PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQA 439
Query: 417 --PAPPHISHHPSASP---FPLSLPNHSPLH-SFTPTLQP---PAHSHHPNMFAPPTALP 467
+P + P SP PLSLP PL S +P + P P H + +
Sbjct: 440 SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 468 PPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQH 527
P PL+S + P T S + L + + SL PPP L+T
Sbjct: 500 PQAPLSSLIM-----PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP-LQTASAPL 553
Query: 528 QHQHQHTHQHTHQHTFTPFPHAIPPTAIM--PTPAPPMFDKYPTKVDPFYRHSLFHSYP- 584
H T P P PP+ + P P P + P P
Sbjct: 554 TTPHLETPPCP-----APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608
Query: 585 PAVSGI---PPMIPPTGPFGSLQGAFQPKLTDPFRPMLR-KPGKWCAMHVHIAWQIYHHQ 640
P +S + PP PP LQ P + P P+ P A+ VH+ +
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668
Query: 641 QKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTP 700
Q P S P PS P LA P + A P +P
Sbjct: 669 PSPPVQAPFSPP----------ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718
Query: 701 FGPPP 705
PP
Sbjct: 719 SATPP 723
Score = 68.6 bits (166), Expect = 4e-11
Identities = 79/312 (25%), Positives = 120/312 (38%), Gaps = 59/312 (18%)
Query: 256 LPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQL 315
LP + + P P +S L ++ + + + P P V P P + P
Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686
Query: 316 RAPSPD----PDL----VQRTEAPPQPPPLS---TQPPQGPPEAQLQPAPQPQVQRPPRP 364
+ +P P L +Q +PP PP+S T PPQ PP P P P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746
Query: 365 QSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSL--NSLSSSRSSTPAKTQPAPPHI 422
SP+ +PP+ A P Q P ++ S L+ + ++ P + P+PP
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP-- 804
Query: 423 SHHPSASPF---------PLSL-PNHSPLHSFTPTLQ-PPAHSHHPNMFA---PPT---- 464
+ P +PF PL+ P +P P LQ PP+ P + A PPT
Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864
Query: 465 ----------AL---PPPPPLTSGSL-----QVAGHPAGSTYSEQDILRQELNTRFLASQ 506
AL PPPPP S S +AGH + +T + +++ +
Sbjct: 865 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD--------S 916
Query: 507 SADRGASLGPPP 518
+ GA+ PPP
Sbjct: 917 GPEGGAAASPPP 928
Score = 62.0 bits (149), Expect = 3e-09
Identities = 158/681 (23%), Positives = 221/681 (32%), Gaps = 114/681 (16%)
Query: 3 GPTRGHGLRKKRRSRSQRDR--ERRSRGGLGAGAAG--GGGAGRTRALSLASSSGSDKED 58
GP GLR R + E R L AGA G T + ++A S + +
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 59 NGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQ 118
G P + +RPRPP R+S S+ + +P +R
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASE------------------HSTTEPSPAARRRP 228
Query: 119 TPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPG 178
+ +R A S S + LS P H + K PK L+ L+P
Sbjct: 229 SAGGGLQRPA---SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PKGLQALRPP 283
Query: 179 QNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEK 238
Q + D+ A G S + PS GT + D ++
Sbjct: 284 QVTPPRKDAAPALGPLSS----------SPLATPSPSGT-------KARPVPPPDNAATP 326
Query: 239 LFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDP 298
L T + P L LP + P P + L + P + P
Sbjct: 327 LPAT--LPPSPPLAT-PLPLAPPSPSAP--PSLQTLPSPPATPPSQAPPSMTTPPMQAPP 381
Query: 299 CPQVAQPI--PQPQTEPQLRAPSPDP--------------DLVQRTEAPPQPPPLSTQ-- 340
Q PI P T P L+AP P P +Q T + P TQ
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAP-PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS 440
Query: 341 ------PPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHP--SAQSLSQPLS 392
P PP++ AP PP S + + P+ HP + SL+
Sbjct: 441 LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500
Query: 393 AYNSSSLSLNSLSSSRSSTPAKTQPAP-----PHISHHPSASPFPLSLPNHSPLHSFTPT 447
SSL + L + S P Q P P + + PS +P PL + +PL TP
Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS-APL--TTPH 557
Query: 448 LQPPAHSHHPNMFAPPTALPPPPPLTSGSLQV---AGHPAGSTYSEQDILRQELNTRFLA 504
L+ P + APP+ L PPP T S+ PA ++ Q + L+
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP 617
Query: 505 SQSADRGASLGP---------PPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPH------- 548
A +L P P L H Q F+P P
Sbjct: 618 PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677
Query: 549 ------AIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGI-PPMIPPTGPFG 601
+ P+A P+ APP P +V P S S P + S PP PP
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPP----SPPASPPMSPSATPPPQAPPPLAAP 733
Query: 602 SLQGAFQPKLTDPFRPMLRKP 622
LQ P + P P P
Sbjct: 734 PLQVPPSPPASPPMSPSATPP 754
Score = 52.4 bits (124), Expect = 3e-06
Identities = 72/253 (28%), Positives = 96/253 (37%), Gaps = 60/253 (23%)
Query: 292 PVVLKDPCPQVAQPI-----PQPQTEPQLRAPS----PDPDLVQRTEAPPQPP------P 336
P + P P + P+ P PQ P L P P P +AP P P
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 823
Query: 337 LSTQPPQGPPEA-----QLQPAP--QPQVQRPPRPQSP-----------TQLLHQNLPPV 378
L+T PPQ PP Q+ P+P P +Q P RP +P T L PP
Sbjct: 824 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 883
Query: 379 QAHPSAQSLSQP-LSAYNSSSLS----LNSLSSSRSSTPAKTQPAPPHISH-HPSA---S 429
+ + +LS P L+ ++SS+ S L S A + P ++ HP+A
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 943
Query: 430 PFPLSLPNHSPLHSFTPTLQPPA-------------HSHHPNMFAP-PTALPP-PPPLTS 474
P P +P P PPA + P P P AL P P P TS
Sbjct: 944 PAPPLAFRGAP---GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 1000
Query: 475 GSLQVAGHPAGST 487
G AG AG++
Sbjct: 1001 GGKAAAGAGAGAS 1013
Score = 39.3 bits (90), Expect = 0.023
Identities = 104/493 (21%), Positives = 144/493 (29%), Gaps = 65/493 (13%)
Query: 331 PPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
P PP S + + PP P P R P L + L A+ +
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG--KA 147
Query: 391 LSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHH-----------PSASPFPLSLPNHS 439
A S+LS + + TP PA S PSA P P P
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP---PTEG 204
Query: 440 PLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELN 499
P S + + P P+A S SL + P S R
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Query: 500 TRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHA-----IPPTA 554
SQ +G PP + + + TP P +PP
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPP---RKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 555 IMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDP 614
TP P P P S PP++ +P PP P P +T P
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS--PPATP----PSQAPPSMTTP 375
Query: 615 FRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGA 674
PM P + + + +Q+ P L L + G A
Sbjct: 376 --PMQAPPSLQTIPPIQVPHSL------TSPSLQAPPSPL--ALSSLQATTSLGSPTLQA 425
Query: 675 IHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAH---------LEPFNRPST 725
H ++ T S + P TP PP + PA+ + P + P T
Sbjct: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
Query: 726 FTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPW 785
L A+ A S +P + P ++ S+ PPS TPP
Sbjct: 486 IHPLQALSSLA-------SHSPQAPLSSLIMPPLETQSS---------LAPPSLQTPPAS 529
Query: 786 LKPGELERSASAA 798
L LE S A
Sbjct: 530 LTTPPLENLPSLA 542
Score = 35.0 bits (79), Expect = 0.44
Identities = 81/359 (22%), Positives = 126/359 (35%), Gaps = 67/359 (18%)
Query: 696 PTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKD 755
P G+P PPP + PAA + A GG P P +
Sbjct: 29 PPGSPRPPPP-----VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
Query: 756 GPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSK 815
G S +N ++ R R PP+ T PG + A+ R + ++ +S
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNT-----SPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 816 DD-----KERESVEK--------RHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEARE 862
++ K E+ ++ R +S P+P P A + TE
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV--------GLP 190
Query: 863 KDKPKERERDHSES-RKDLA-ADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYV 920
+ P R R +E RK ++ A EH E AA + P
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTE-----------PSPAARRRPSAGGGLQRPAS 239
Query: 921 RTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASE 980
R+ + SA P S+ +R +G P P S+ K P+ Q R +
Sbjct: 240 RS-LSSSATPLSSPARSGPSARGTP--RAPAHPSQPK------------PKGLQALRPPQ 284
Query: 981 PPPPNSSSSVHPGPLASMPM-TVGVTGIH------PMNSISSLDRTRMMTPFMGISPLP 1032
PP ++ GPL+S P+ T +G P N+ + L T +P + +PLP
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA-TPLP 342
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 78.6 bits (192), Expect = 3e-14
Identities = 205/936 (21%), Positives = 298/936 (31%), Gaps = 215/936 (22%)
Query: 56 KEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFV--TFEALEKDVALKPQER 113
KE+ + S P P + K+ S+++ + M S T+E+ E+D KP
Sbjct: 554 KEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKC-KPMSY 612
Query: 114 VEKRQTPLTKKKREALTNGLSFHSKKSRL-----SHPHHYSSDRENDRNLCQHLGKRKKM 168
EKRQ L K G H +SR S+P D E +
Sbjct: 613 EEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK------------ 660
Query: 169 PKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQE 228
P LR+L+ SC + + + SS + S S +S+S E
Sbjct: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSS------------ESESSSE 708
Query: 229 EKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEP 288
+SD+ E + P K R Q+K +
Sbjct: 709 SSSSDS-----------------------EDSETEMAPKSKKKGHPGREQKKHHHHHHQQ 745
Query: 289 IFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEA 348
+ + P P QP P PQ P P P P Q+ + PP PPP + P Q P
Sbjct: 746 MQQA-----PAPVPQQPPPPPQQPP----PPPPP---QQQQQPPPPPPPPSMPQQAAPAM 793
Query: 349 QLQPAPQPQVQRPP-RPQSP----------TQ-LLHQNLPPVQAHPSAQSLSQPLSAYNS 396
+ P P Q P PQ P TQ +LH P + H L QP
Sbjct: 794 KSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPH-----LPQPPEHSTP 848
Query: 397 SSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHH 456
L+ +++ S + A Q + + P P P SP + TP L P +
Sbjct: 849 PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQP 908
Query: 457 PNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGP 516
P + PP PPLTS +Q+ Y +Q + + + T L S P
Sbjct: 909 PQVLLEDEE-PPAPPLTSMQMQL--------YLQQ-LQKVQPPTPLLPSVKVQS----QP 954
Query: 517 PPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYR 576
PP L H Q Q Q P P PP P P P + P +
Sbjct: 955 PPPLPPPPHPSVQQ-----QLQQQPPPPPPPQPQPPPQQQHQPPP-----RPVHLQPM-Q 1003
Query: 577 HSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQI 636
S PP G P PP G QP P +P I
Sbjct: 1004 FSTHIQQPPPPQGQQPPHPPPGQ--------QPPPPQPAKPQ---------------QVI 1040
Query: 637 YHHQQKVKKQMQSDPHKLDF--GLKPEFLSRPPGPSLFGAIHH---PHDLARPSTL-FSA 690
HH + +SDP+ + P S F ++ H P +P A
Sbjct: 1041 QHHHS--PRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRA 1098
Query: 691 AGAAHP----------------TGTPFGP-----PPHHSNFLNPAAHL--EPFNRPSTFT 727
A P PF P PP H + HL P +P
Sbjct: 1099 ASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPV--- 1155
Query: 728 GLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLK 787
+G P + P QN P P + P P P K
Sbjct: 1156 -----------DVGRPVIRPPE----------QNAPPPGAPDKDKQKQEPKTPVAPK--K 1192
Query: 788 PGELERSASAAA----HDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALG 843
+++ S A+ H + SS S + R + EK A
Sbjct: 1193 DLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQA------E 1246
Query: 844 HTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGR 903
H E++R ++D ++ R H E+R+ + + +E
Sbjct: 1247 HAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQE-------------- 1292
Query: 904 AAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAE 939
++ +Q A V + TP +S++P S ++ E
Sbjct: 1293 QQQQQQQQAAAVAA--AATPQAQSSQPQSMLDQQRE 1326
Score = 45.1 bits (105), Expect = 4e-04
Identities = 45/165 (27%), Positives = 55/165 (33%), Gaps = 33/165 (20%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQ-PPQGPPEAQLQPAPQP 356
P Q QP P P P+ PDL+ +T PP Q PP PP+ Q PAP P
Sbjct: 206 PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAP 265
Query: 357 QVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQ 416
Q PVQ+HP P+ A + ++ T T
Sbjct: 266 Q-------------------PVQSHP-------PIIAATPQPVKTKKGVKRKADTTTPTT 299
Query: 417 PAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQP----PAHSHHP 457
P H PS P P + S P P P HP
Sbjct: 300 IDPIH--EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHP 342
Score = 36.6 bits (83), Expect = 0.15
Identities = 47/196 (23%), Positives = 78/196 (39%), Gaps = 48/196 (24%)
Query: 777 PSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPV 836
P+ P P + P S+S ++ D D D DS + + E E+ + H
Sbjct: 471 PAVPPPTKVVAPPSSSDSSSDSSSDSDSSTD--DSEEERAQRLAELQEQLKAVH------ 522
Query: 837 LPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKD 896
EQ+ A +++KPK++E+D E +K ++HK KE
Sbjct: 523 -------------EQLAA---LSQPQQNKPKKKEKDKKEKKK----EKHKRKE------- 555
Query: 897 GHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGE--PAYENPK--K 952
E K A+ P P +T S+ N S +E P K + P YE+ + K
Sbjct: 556 -------EVEENKKSKAKEPPP-KKTKKNNSSNSN-VSKKEPAPMKSKPPPTYESEEEDK 606
Query: 953 SSEVKVKEERKEDHDL 968
+ +E+R+ D+
Sbjct: 607 CKPMSYEEKRQLSLDI 622
Score = 35.8 bits (81), Expect = 0.26
Identities = 62/282 (21%), Positives = 98/282 (34%), Gaps = 31/282 (10%)
Query: 944 EPAYENPKKSSEVKVKEERKEDHDLPPEAPQT--HRASEPPPP-----NSSSS----VHP 992
+P PKK + K KE++KE H E + +A EPPP NSS+S P
Sbjct: 530 QPQQNKPKKKEKDK-KEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEP 588
Query: 993 GPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGE--RFPYPSFHWDPIRDP 1050
P+ S P + S + R ++ + I+ LPG + R + +P
Sbjct: 589 APMKSKPPPTYESEEEDKCKPMSYEEKRQLS--LDINKLPGEKLGRVVHIIQSREPSLKN 646
Query: 1051 LRDPYRELDIHRRDPLGRDFLLR--NDPLHRLSTPRLYEAD--------RSFRDREPHDY 1100
E+D P L R L + P+ + D + F E
Sbjct: 647 SNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESS 706
Query: 1101 SHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSL 1160
S + + ++ GH ++ H + H + PA + P P
Sbjct: 707 SESSSSDSEDSETEMAPKSKKKGHPGREQKKH----HHHHHQQMQQAPAPVPQQPPPPPQ 762
Query: 1161 ITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLIST 1202
P P + P + + P A S+PPP I+T
Sbjct: 763 QPPPPPPPQQQQQPPPPPPPPSMPQQAAP-AMKSSPPPFIAT 803
Score = 33.9 bits (76), Expect = 0.99
Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 22/116 (18%)
Query: 289 IFEPVVLKDPCPQVAQPIPQP-------QTEPQLRAPSPDPDLVQR-------TEAPPQP 334
+ P L+ P P QP P P Q+ P + A +P P ++ T P
Sbjct: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
Query: 335 PPLSTQPPQGPPEAQLQPAPQ-PQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQ 389
P+ +PP PPE + Q + RP +P +++P Q HP+ + S+
Sbjct: 301 DPIH-EPPSLPPEPKTTKLGQRRESSRPVKPPK------KDVPDSQQHPAPEKSSK 349
Score = 31.2 bits (69), Expect = 6.4
Identities = 41/162 (25%), Positives = 56/162 (34%), Gaps = 43/162 (26%)
Query: 327 RTEAPPQPPPLSTQP----PQGPPEAQLQPAPQPQVQRPPRP-QSPTQLLHQNLPPVQAH 381
R E P +ST P PP+ Q P VQ P P + T L P +
Sbjct: 183 RKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVV 242
Query: 382 PSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPL 441
P QPL ++ P QP PP +P P + +H P+
Sbjct: 243 P-----PQPL----------------QTPPPVPPQPQPP-------PAPAPQPVQSHPPI 274
Query: 442 HSFTPT-------LQPPAHSHHPNMFAP---PTALPPPPPLT 473
+ TP ++ A + P P P +LPP P T
Sbjct: 275 IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTT 316
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 76.6 bits (187), Expect = 1e-13
Identities = 132/550 (24%), Positives = 190/550 (34%), Gaps = 81/550 (14%)
Query: 3 GPTRGHGLRKKRRSRSQRDR--ERRSRGGLGAGAAG--GGGAGRTRALSLASSSGSDKED 58
GP GLR R + E R L AGA G T + ++A S + +
Sbjct: 118 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 177
Query: 59 NGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQ 118
G P + +RPRPP R+S S+ + +P +R
Sbjct: 178 VGLPRPAPSARPRPPTEGPRKSVSSASE------------------HSTTEPSPAARRRP 219
Query: 119 TPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPG 178
+ +R A S S + LS P H + K PK L+ L+P
Sbjct: 220 SAGGGLQRPA---SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PKGLQALRPP 274
Query: 179 QNSCRDSDSESASGE-SKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSE 237
Q + D+ A G S + S SAP SL T + + S S
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 238 KLFNTVIVNKDPELGVGT----------LPEHDSQDAGPIVPKISGLERSQEKSQDCCKE 287
+ P + T LP + + P P +S L ++ +
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394
Query: 288 PIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPP-LSTQPPQGPP 346
+ + P P V P P + P +PS P P Q PP L+ P Q PP
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPV--SPSATP--------PSQAPPSLAAPPLQVPP 444
Query: 347 EAQLQPAPQPQVQRPPRPQSPTQL--LHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSL 404
P P PP+ P L PP QA P+ + PL A S S
Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL--ATPPLQALPSPPASFPGQ 502
Query: 405 S--SSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQ----PPAHSHHPN 458
+ S +S P PP + A+P L +P P +PTLQ PP +
Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPA---SPTLQAPRRPPTPGPDTS 558
Query: 459 MFAPPTAL-----PPPPPLTSGSL-----QVAGHPAGSTYSEQDILRQELNTRFLASQSA 508
+ P L PPPPP S S +AGH + +T + +++ +
Sbjct: 559 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD--------SGP 610
Query: 509 DRGASLGPPP 518
+ GA+ PPP
Sbjct: 611 EGGAAASPPP 620
Score = 65.9 bits (159), Expect = 2e-10
Identities = 132/573 (23%), Positives = 187/573 (32%), Gaps = 135/573 (23%)
Query: 249 PELGVGTLPEHDSQDAGPIVPKI----SGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQ 304
P V + EH + + P + GL+R +S P+ P A+
Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP----------AR 245
Query: 305 PIPQPQTEPQLRA-PS-PDPDLVQRTEAPPQ--PPPLSTQPPQGPPEAQLQPAPQPQVQR 360
P + P+ A PS P P +Q PPQ PP P GP + P P
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALR-PPQVTPPRKDAAPALGPLSSSPLATPSPSA-- 302
Query: 361 PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQP--A 418
PP P +P L Q LP A P +Q+ + S + + + +S S +P T P A
Sbjct: 303 PPSPSAPPSL--QTLPSPPATPPSQATT---SLGSPTLQATHSFLPSPPLSPLATPPPQA 357
Query: 419 PPHISHHP-SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSL 477
PP ++ P A P P + P SPL TP+ Q P ++ ++ P + PP PP+ +
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLA--TPSPQAP-NALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 478 QVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQH 537
A P + A+ + SL PP
Sbjct: 415 PPASPPVSPS----------------ATPPSQAPPSLAAPPL------------------ 440
Query: 538 THQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPT 597
P P A PP + P+ PP P P PPA++ P P+
Sbjct: 441 ----QVPPSPPASPPMS--PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPS 494
Query: 598 GPFGSL-QGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDF 656
P Q F P + P P+ P Q+ P
Sbjct: 495 PPASFPGQAPFSPSASLPMSPLATPPP------------------------QAPPV---- 526
Query: 657 GLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAH 716
L L PP P + P P S +G GPPP
Sbjct: 527 -LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP----------- 574
Query: 717 LEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNP----------H 766
P PS+ G + G + + TP + G+ GP ++P
Sbjct: 575 -PPSRSPSS----TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 629
Query: 767 EPWNR------LHRTPPSFPTP-PPWLKPGELE 792
W+R R P P P PP PG +
Sbjct: 630 AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 662
Score = 53.1 bits (126), Expect = 2e-06
Identities = 72/246 (29%), Positives = 94/246 (38%), Gaps = 59/246 (23%)
Query: 298 PCPQVAQPI----PQPQTEPQLRAPS----PDPDLVQRTEAPPQPP------PLSTQPPQ 343
P P A P+ P PQ P L P P P +AP P PL+T PPQ
Sbjct: 463 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 522
Query: 344 GPPEA-----QLQPAP--QPQVQRPPRPQSP-----------TQLLHQNLPPVQAHPSAQ 385
PP Q+ P+P P +Q P RP +P T L PP + +
Sbjct: 523 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 582
Query: 386 SLSQP-LSAYNSSSLS----LNSLSSSRSSTPAKTQPAPPHISH-HPSA---SPFPLSLP 436
+LS P L+ ++SS+ S L S A + P ++ HP+A P P
Sbjct: 583 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 642
Query: 437 NHSPLHSFTPTLQPPA-------------HSHHPNMFAP-PTALPP-PPPLTSGSLQVAG 481
+P P PPA + P P P AL P P P TSG AG
Sbjct: 643 RGAP---GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAG 699
Query: 482 HPAGST 487
AG++
Sbjct: 700 AGAGAS 705
Score = 47.8 bits (112), Expect = 7e-05
Identities = 74/312 (23%), Positives = 102/312 (32%), Gaps = 59/312 (18%)
Query: 331 PPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
P P P + + P P P + P + P + + PS + +P
Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 219
Query: 391 LSAYNSSSLSLNSLSSSRS--STPAKTQPAP---PHISHHPSASPFPLSLPNHSPLHSFT 445
+ + SLSSS + S+PA++ P+ P HPS P P L P
Sbjct: 220 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS-QPKPKGLQALRP----- 273
Query: 446 PTLQPPAHSHHPNM-------FAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQEL 498
P + PP P + A P+ PP P SLQ P + S+
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA------- 326
Query: 499 NTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPT 558
T L S + S P P L TP P A P A+ P
Sbjct: 327 -TTSLGSPTLQATHSFLPSPPLSP-------------------LATPPPQAPPALALPPL 366
Query: 559 PAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGI------PPMIPPTGPFGSLQGAFQPKLT 612
APP P + P S P A + + P PP P +Q F P +
Sbjct: 367 QAPPSPPASP-PLSPLATPS-----PQAPNALAVHLLQAPFSPPPSP--PVQAPFSPPAS 418
Query: 613 DPFRPMLRKPGK 624
P P P +
Sbjct: 419 PPVSPSATPPSQ 430
Score = 31.2 bits (69), Expect = 6.4
Identities = 58/271 (21%), Positives = 84/271 (30%), Gaps = 50/271 (18%)
Query: 776 PPSFPTPPPWLKPGELERSASAAAHDRDRDVDKR----------------DSSVSKDDKE 819
PP P PPP + P L +A A R ++ + S+
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPAS 88
Query: 820 RESVEKRHSSHPSPAPV-LPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRK 878
+ + SP PV P A G TR ++ + + R
Sbjct: 89 GRGERAPPAKNTSPGPVSSPGRASGTTRPGP---LGQKGLRISAEETVARGKATEAPKRS 145
Query: 879 DLAADEHKAKEGHLP--EKDGHGHEGRAAGEEAKQLARVPSPYVRTPV------VESARP 930
L+A + G P RAAG E PS R P V SA
Sbjct: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205
Query: 931 NSTSSREAEPRKGEPA------------------YENPKKSSEVKVKEERKEDHDLPPEA 972
+ST+ R+ A +P +S R H P+
Sbjct: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK- 264
Query: 973 PQTHRASEPP---PPNSSSSVHPGPLASMPM 1000
P+ +A PP PP ++ GPL+S P+
Sbjct: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPL 295
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 73.2 bits (178), Expect = 1e-12
Identities = 97/373 (26%), Positives = 129/373 (34%), Gaps = 97/373 (26%)
Query: 256 LPEHDSQDAGPIVPKISGLERSQ--EKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEP 313
L + S P VP++ + SQ E SQ K+P +P + P Q +P PQP +
Sbjct: 273 LQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQ-QPAQQQQPAQQPKKPSPQPSSPR 331
Query: 314 QLRAP---SPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQ------RPPRP 364
Q++ SP + PP+ P + T P PP A P +P + PP P
Sbjct: 332 QVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPP-AHPPPDRKPPLAAALGEAEPPGP 390
Query: 365 QSPTQLLHQNLPPVQAHPSAQSLSQPL---------SAYNSSSLSLNSLSSSRS--STPA 413
T L +PP AHP+ PL S+Y + + +S S S +
Sbjct: 391 VDATDLPKVQIPP-PAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQS 449
Query: 414 KTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLT 473
+ P P A P LP H H + P PP P F PP A+PPP P
Sbjct: 450 MMKTEGPSYGALPPAYGPPAHLPYHP--HVYPPNPPPPPVPPPPASFPPP-AIPPPTP-- 504
Query: 474 SGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQH 533
G+P PPP
Sbjct: 505 -------GYPP-------------------------------PPP--------------- 511
Query: 534 THQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPP-AVSGIPP 592
T+ F P P +PPT +P PP P P + PP +PP
Sbjct: 512 ----TYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPP-------PAVPPGGQPPVPP 560
Query: 593 MIPPTG--PFGSL 603
IPP G P G L
Sbjct: 561 PIPPPGMPPVGGL 573
Score = 62.0 bits (149), Expect = 3e-09
Identities = 84/329 (25%), Positives = 117/329 (35%), Gaps = 72/329 (21%)
Query: 294 VLKDPCPQVAQPIPQPQ------TEPQLRAP---SPDPDLVQRTEAPPQPPPLSTQPPQG 344
VL+D C Q+ Q + T QL+ P P P + Q ++ P +QP Q
Sbjct: 246 VLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQK 305
Query: 345 PPEA---QLQPAPQPQVQRPPRPQSPTQLLHQNL-----------PPVQAHPSAQSLSQP 390
P+ Q QPA QP+ + P+P SP Q+ + PP P ++ P
Sbjct: 306 DPQQPAQQQQPAQQPK-KPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPP 364
Query: 391 LSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQP 450
L + L+++ P P + P P + P +P+H QP
Sbjct: 365 LPPAHPPPDRKPPLAAALGEA---EPPGPVDATDLPKVQIPPPAHP--APVH------QP 413
Query: 451 PAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADR 510
P H P PP PPP +G + + +G Y L S
Sbjct: 414 PPLPHRP----PP---PPPSSYMTGMSTTSSYMSGEGYQS------------LQSMMKTE 454
Query: 511 GASLG--PPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYP 568
G S G PP Y H H H + P P PP + P PP YP
Sbjct: 455 GPSYGALPPAY-------GPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYP 507
Query: 569 TKVDPFYRHSLFHSYPPAVSGIPPMIPPT 597
P Y ++PP PP +PPT
Sbjct: 508 PP-PPTYN----PNFPPP----PPRLPPT 527
Score = 41.6 bits (96), Expect = 0.005
Identities = 41/169 (24%), Positives = 62/169 (36%), Gaps = 44/169 (26%)
Query: 911 QLARVPS--PYVRTPVVESARPNSTSSREAEPRKGEPAY--------ENPKKSSE----- 955
QL + PS P + P V+ ++P S SS ++P++ +P + PKK S
Sbjct: 272 QLQQPPSLQPTPQVPQVQQSQP-SQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSP 330
Query: 956 --------VKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGI 1007
V KEE K PP+ P+ P PP HP P P+ +
Sbjct: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPP-----AHPPPDRKPPLAAALGEA 385
Query: 1008 HPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYR 1056
P + + D ++ P P H P+ P P+R
Sbjct: 386 EPPGPVDATDLPKVQIP---------------PPAHPAPVHQPPPLPHR 419
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 70.5 bits (171), Expect = 1e-11
Identities = 98/393 (24%), Positives = 136/393 (34%), Gaps = 56/393 (14%)
Query: 252 GVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVA---QP--- 305
G G+ DSQ + V S + + +Q C P+ E VL P + QP
Sbjct: 619 GQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAA 678
Query: 306 -------IPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQ-----LQPA 353
+P P P L+ PDP + PP P+ T P Q P Q QP
Sbjct: 679 PGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPT 738
Query: 354 PQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA 413
P PQV P+P P Q + +LPP A S L L L + P
Sbjct: 739 PLPQV-LAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPL----AQVPP 793
Query: 414 KTQPAP--PHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
+ P P P I+ P +LP+ L + T PP P + P A P PP
Sbjct: 794 QMPPIPVVPPITPLAGIDGLPPALPD---LPTATVPPVPPPQYFSPAVILPSLAAPLPPA 850
Query: 472 LTSGSLQVA--GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQH 529
+ LQ HP G+ L T + + ++ PP H
Sbjct: 851 SPALPLQAVKLPHPPGAP------LAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVA 904
Query: 530 QHQHTHQHTHQHTFTPFPHAIP---PTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPA 586
Q +P A P PT + P+P + + T P + PP
Sbjct: 905 QLPGQ---------PVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQP--------ALPPQ 947
Query: 587 VSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPML 619
+ P + P P Q P+ T P +P+L
Sbjct: 948 PTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVL 980
Score = 56.2 bits (134), Expect = 2e-07
Identities = 52/178 (29%), Positives = 66/178 (37%), Gaps = 41/178 (23%)
Query: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQP--PPLSTQPPQG--PPEAQLQPAP-- 354
Q P PQ P PSP + PPQP PP T PPQ PP+ L P P
Sbjct: 909 QPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVL 968
Query: 355 QPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAK 414
PQ RPP+P P Q + LPP P +L P +
Sbjct: 969 PPQPTRPPQPVLPPQPM---LPPQPVLPPQPAL------------------------PVR 1001
Query: 415 TQPAPPHISHH--PSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPP 470
+P PH+ P+A+P L H ++ Q P + PP A+ PP
Sbjct: 1002 PEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQV------PTVPVPPAAVLSPP 1053
Score = 48.9 bits (115), Expect = 3e-05
Identities = 82/347 (23%), Positives = 109/347 (31%), Gaps = 66/347 (19%)
Query: 220 FCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQE 279
F + D +KA D SE + D GT P H S GL +E
Sbjct: 1246 FIEQMKDVMDKAEDMLSED------TDADRGSDPGTSPPHLST---------CGLGTGEE 1290
Query: 280 KSQDCCKEPIFEPVVLKDP------CPQVAQPIPQ-PQTEPQLRAPSPDPDLVQRTEA-- 330
Q P+++ VL CP P P+ P++ P L S P+ Q +
Sbjct: 1291 SRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYK 1350
Query: 331 -------------------------PPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQ 365
PP PP P P A Q P P P
Sbjct: 1351 DQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPA 1410
Query: 366 SPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSL--------------SSSRSST 411
S T Q S SQPL+ + + L++ L S+ +S
Sbjct: 1411 SGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASA 1470
Query: 412 PAKTQPAP-PHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPP 470
P + P P P S H S +P P +L +PL A S P+ PT P PP
Sbjct: 1471 PREPLPPPAPEPSPH-SGTPQP-ALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPP 1528
Query: 471 PLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPP 517
+ G S L ++L T AS G P
Sbjct: 1529 SALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTP 1575
Score = 42.0 bits (97), Expect = 0.004
Identities = 53/171 (30%), Positives = 70/171 (40%), Gaps = 33/171 (19%)
Query: 287 EPIFEPVVLKDPCPQVA-QPI--PQPQTEPQLRAPSPDPDLVQRTEAPPQPP-PLSTQP- 341
+P P + P P + QP+ PQP PQ P P P L + PPQP P+ +P
Sbjct: 947 QPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLP-PQPMLPPQPVLPPQPALPVRPEPL 1005
Query: 342 ---------PQGPPEAQL---QPAP---QPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQS 386
P P +Q+ PAP Q P P P +L LP V + +
Sbjct: 1006 QPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPEL 1065
Query: 387 LSQPLSAYNSSSLSLNSLSSSRSSTPAKT----QPAPPHISHHPS-ASPFP 432
L Q S SL ++S+S S P +T PA P + P ASP P
Sbjct: 1066 LPQFPS-------SLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCP 1109
Score = 41.2 bits (95), Expect = 0.006
Identities = 62/249 (24%), Positives = 86/249 (34%), Gaps = 70/249 (28%)
Query: 291 EPVVLKDPCPQVAQPIPQPQTEPQLRAPS-------PDPDLVQRTEAPPQPPPLSTQPPQ 343
+PVV P P P P + Q+ AP+ P L + PPQ PP+ PP
Sbjct: 747 QPVVPLQPVPPHLPPYLAPAS--QVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI 804
Query: 344 GP--------------PEAQLQPAPQPQVQRP----PRPQSPTQLLHQNLPPVQA----H 381
P P A + P P PQ P P +P LP +QA H
Sbjct: 805 TPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALP-LQAVKLPH 863
Query: 382 PSAQSLSQP----------------LSAYNSSSLSLNSL-----------SSSRSSTPAK 414
P L+ P ++ ++LS++S ++ P
Sbjct: 864 PPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTD 923
Query: 415 TQPAPPHISHHPSASPFPLSLPNH-----SPLHSFTPTLQP-----PAHSHHPNMFAPPT 464
P+P H + A+P +LP P+ PTL P P + P PP
Sbjct: 924 VPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQ 983
Query: 465 A-LPPPPPL 472
LPP P L
Sbjct: 984 PMLPPQPVL 992
Score = 33.5 bits (75), Expect = 1.3
Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 5/69 (7%)
Query: 1148 PASLDGHLPHPSL-ITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLISTLGGR 1206
P SL H P P++ P LP P PT Q + PP L+ P PL L +
Sbjct: 692 PPSLQQHFPDPAMSFAPVLPPPSTPM--PTGPGQPAPPGQQPPP--LAQPTPLPQVLAPQ 747
Query: 1207 PVSPRRTTP 1215
PV P + P
Sbjct: 748 PVVPLQPVP 756
Score = 32.0 bits (71), Expect = 3.7
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 1155 LPHPSLITPGLP-SMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRT 1213
LPHP PG P +M I P A LL PP A + ++ L G+PV P
Sbjct: 861 LPHP----PGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAF 916
Query: 1214 TPLSAEIRERPPSHTLKDIEA 1234
++ P HT++++ A
Sbjct: 917 PQMAPTDVPPSPHHTVQNMRA 937
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 68.6 bits (166), Expect = 4e-11
Identities = 151/666 (22%), Positives = 217/666 (32%), Gaps = 137/666 (20%)
Query: 331 PPQPPPLSTQPPQGPPEAQLQP-----APQP-----QVQRPPRPQSPTQLLHQNLPPVQA 380
P QPP + PP PP Q QP PQP VQ P P SP Q +H +PP
Sbjct: 310 PTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHP-SPPQGMH--MPPQLE 366
Query: 381 HPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQ----PAPPHISHHPSASPFPLSLP 436
P P++ ++ +N TP + P+ P + P P P P
Sbjct: 367 TPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFP 426
Query: 437 NHSPLHSFTPTLQPPAHSHHPNMFAPPTALP-------PPPPLTSGS--LQVAGHPAGST 487
H+P PN F+ P LP PPPP L V+G P +
Sbjct: 427 QHTP-------------GPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPS 473
Query: 488 YSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFP 547
+ FL +S PPP L H Q +P P
Sbjct: 474 H------------LFLEQRSPPPPP---PPPTLLNSSHPVPTQ-------------SPLP 505
Query: 548 HAIPPTAIMPTPAPPMFDK-YPTK--VDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQ 604
P A P+F + P + + P + H P + P IPP PF L
Sbjct: 506 FTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPF--LP 563
Query: 605 GAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLS 664
G QP L +P L+ P +H H Q + Q Q P +P
Sbjct: 564 GPGQPFLPTHTQPNLQGP-------LHPPLPPPHQPQPQQPQQQPPPQH-----QPP--H 609
Query: 665 RPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPP-----HHSNFLNPAAHLEP 719
+PP H P +P P P PP HH + P L P
Sbjct: 610 QPP--------HQPPPQHQPP----------PQHPPQHPPQHQHHHHHHHLSVPPPPLMP 651
Query: 720 FNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPP-- 777
++P + A + + G + + QN S P ++ T P
Sbjct: 652 MSQPQFRPHVQTAQPQA----SSSRMQCPQRQGLRHNTTSQNVSK--RPMQQMQPTAPRN 705
Query: 778 ----SFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSP 833
P P + +E S+S + V VS R R S +
Sbjct: 706 SNLRELPIAPSHV----IEMSSSRCSATPSAQV---KPIVSASPPSRAVAGSRSSQGKTE 758
Query: 834 APVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLP 893
V P + + + A TE ++D+ R E +K L + K KE
Sbjct: 759 VKVKPASPVAQPKE-----EAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQ 813
Query: 894 EKDGHGHEG--RAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPK 951
++ G + ++ +QL P P + ++ P+ T+ P G +N K
Sbjct: 814 QQAGARKKELLERLAQQQQQLYAPPPPAEQEE--QALSPSPTNGNPLLPFPGAQVRQNVK 871
Query: 952 KSSEVK 957
VK
Sbjct: 872 NRLLVK 877
Score = 61.2 bits (147), Expect = 6e-09
Identities = 76/275 (27%), Positives = 96/275 (34%), Gaps = 49/275 (17%)
Query: 307 PQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRP----- 361
P+P PQ R P P P+ Q T P P +QPP+ P + Q + P PQ + P
Sbjct: 410 PRPAVGPQ-RFPGP-PEFPQHTPGPV--PNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGV 465
Query: 362 -PRPQSPTQL-LHQNLPPV---------QAHP----SAQSLSQPLSAYNSSSLSLNSLSS 406
P+ P+ L L Q PP +HP S +QP A+N
Sbjct: 466 SGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQ-PVFPR 524
Query: 407 SRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTAL 466
R PA P P I H S P + F P QP F P
Sbjct: 525 ERPVRPALQPPGPVGILH--------FSQPGSATTRPFIPPRQP---------FLPGPGQ 567
Query: 467 PPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQ 526
P P T +LQ HP Q +Q Q + PP + H
Sbjct: 568 PFLPTHTQPNLQGPLHPPLPP-PHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHP 626
Query: 527 HQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAP 561
QH QH H H H H ++PP +MP P
Sbjct: 627 PQHPPQHQHHHHHHHL------SVPPPPLMPMSQP 655
Score = 52.0 bits (123), Expect = 3e-06
Identities = 64/244 (26%), Positives = 75/244 (30%), Gaps = 58/244 (23%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPD-------------------LVQRTEAPPQPPPLS 338
P P P+ + Q RAP P D L QR+ PP PPP
Sbjct: 432 PVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTL 491
Query: 339 TQ-----PPQGP-PEAQLQPAPQPQVQRP--PR---------PQSPTQLLHQNLPPVQAH 381
P Q P P Q PA Q Q+P PR P P +LH + P
Sbjct: 492 LNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATT 551
Query: 382 -----PSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLP 436
P L P + + N P QP P P P P P
Sbjct: 552 RPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQP----QQPQQQPPPQHQP 607
Query: 437 NHSPLHSFTPTLQPPA-------------HSHHPNMFAPPTALPPPPPLTSGSLQVAGHP 483
H P H P QPP H HH PP +P P +Q A
Sbjct: 608 PHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQ 667
Query: 484 AGST 487
A S+
Sbjct: 668 ASSS 671
Score = 50.8 bits (120), Expect = 8e-06
Identities = 54/186 (29%), Positives = 70/186 (37%), Gaps = 16/186 (8%)
Query: 300 PQVAQPIPQPQTEPQLRAPS----PDPDLVQRTEAPPQPPPLSTQPPQGP--PEAQLQPA 353
P QP T+P L+ P P P Q + QPPP P Q P P Q QP
Sbjct: 563 PGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPP 622
Query: 354 PQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA 413
PQ Q PP+ Q H ++PP P +Q +P + SSSR P
Sbjct: 623 PQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRP-----HVQTAQPQASSSRMQCPQ 677
Query: 414 KTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPP---P 470
+ S + S P P +P +S L P A SH M + + P
Sbjct: 678 RQGLRHNTTSQNVSKRPMQQMQPT-APRNSNLREL-PIAPSHVIEMSSSRCSATPSAQVK 735
Query: 471 PLTSGS 476
P+ S S
Sbjct: 736 PIVSAS 741
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/153 (30%), Positives = 55/153 (35%), Gaps = 23/153 (15%)
Query: 298 PCPQVAQPIPQPQTEPQLRAP-SPDPDLVQRTEAPPQPPP----------LSTQPPQGPP 346
P PQ Q P PQ +P + P P P + PPQ PP LS PP P
Sbjct: 592 PQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMP 651
Query: 347 EAQLQPAPQPQVQRP----PRPQSP-TQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSL 401
+Q Q P Q +P R Q P Q L N QP + NS+ L
Sbjct: 652 MSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLREL 711
Query: 402 N-------SLSSSRSSTPAKTQPAPPHISHHPS 427
+SSSR S Q P + PS
Sbjct: 712 PIAPSHVIEMSSSRCSATPSAQVKPIVSASPPS 744
Score = 36.2 bits (82), Expect = 0.20
Identities = 40/166 (24%), Positives = 55/166 (33%), Gaps = 36/166 (21%)
Query: 981 PPPPNSSSSVHPGPLAS-MPMTV---------------------------GVTGIHPMNS 1012
PPPP +S HP P S +P T G GI +
Sbjct: 486 PPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQ 545
Query: 1013 ISSLDRTRMMTPFMGISPLPGGERFP---YPSFHWDPIRDPLRDPYRELDIHRRDPLGRD 1069
S + P P PG P P+ P+ PL P++ +
Sbjct: 546 PGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQ-GPLHPPLPPPHQPQPQQPQQQPPPQ 604
Query: 1070 FLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDP 1115
+ P H+ P ++ + P + HHHHHHH LSV P
Sbjct: 605 HQPPHQPPHQ--PPPQHQPPPQHPPQHPPQHQHHHHHHH--LSVPP 646
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 67.4 bits (163), Expect = 8e-11
Identities = 134/580 (23%), Positives = 193/580 (33%), Gaps = 111/580 (19%)
Query: 3 GPTRGHGLRKKRRSRSQRDR--ERRSRGGLGAGAAG--GGGAGRTRALSLASSSGSDKED 58
GP GLR R + E R L AGA G T + ++A S + +
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 59 NGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQ 118
G P + +RPRPP R+S S+ + +P +R
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASE------------------HSTTEPSPAARRRP 228
Query: 119 TPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPG 178
+ +R A S S + LS P H + K PK L+ L+P
Sbjct: 229 SAGGGLQRPA---SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PKGLQALRPP 283
Query: 179 QNSCRDSDSESASGESKGF-----------------------HRSSSRERLS-------- 207
Q + D+ A G H SS +L+
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP 343
Query: 208 DSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGT----------LP 257
SAP SL T + + S S + P + T LP
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403
Query: 258 EHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRA 317
+ + P P +S L ++ + + + P P V P P + P +
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV--S 461
Query: 318 PSPDPDLVQRTEAPPQPPP-LSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQL--LHQN 374
PS P P Q PP L+ P Q PP P P PP+ P L
Sbjct: 462 PSATP--------PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513
Query: 375 LPPVQAHPSAQSLSQPLSAYNSSSLSLNSLS--SSRSSTPAKTQPAPPHISHHPSASPFP 432
PP QA P+ + PL A S S + S +S P PP + A+P
Sbjct: 514 KPPPQAPPAL--ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL- 570
Query: 433 LSLPNHSPLHSFTPTLQ----PPAHSHHPNMFAPPTAL-----PPPPPLTSGSL-----Q 478
L +P P +PTLQ PP ++ P L PPPPP S S
Sbjct: 571 LQVPPSPPA---SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 627
Query: 479 VAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPP 518
+AGH + +T + +++ + + GA+ PPP
Sbjct: 628 LAGHSSSATSTPEELRGYD--------SGPEGGAAASPPP 659
Score = 66.6 bits (161), Expect = 1e-10
Identities = 135/586 (23%), Positives = 191/586 (32%), Gaps = 131/586 (22%)
Query: 249 PELGVGTLPEHDSQDAGPIVPKI----SGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQ 304
P V + EH + + P + GL+R +S P+ P P +
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA-RSGPSARGTP 263
Query: 305 PIPQPQTEPQ---LRAPSPDPDLVQRTEAPPQPPPLSTQPPQGP-PEAQLQPAPQPQVQR 360
P ++P+ L+A P R +A P PLS+ P P P A LQ P +
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA 323
Query: 361 PPRPQSPTQLLHQNLPPVQAHPSA----QSLSQPLSAYNS---SSLSLNSLSSSRSSTPA 413
P S T L LP PSA Q+L P + S +SL +L ++ S P+
Sbjct: 324 TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 383
Query: 414 K------TQP--APPHISHHP-SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPT 464
T P APP ++ P A P P + P SPL TP+ Q P ++ ++ P
Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA--TPSPQAP-NALAVHLLQAPF 440
Query: 465 ALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEF 524
+ PP PP+ + A P + A+ + SL PP
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPS----------------ATPPSQAPPSLAAPPL----- 479
Query: 525 HQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYP 584
P P A PP + P+ PP P P P
Sbjct: 480 -----------------QVPPSPPASPPMS--PSATPPPQAPPPLAAPPLQLAKPPPQAP 520
Query: 585 PAVSGIPPMIPPTGPFGSL-QGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKV 643
PA++ P P+ P Q F P + P P+ P
Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP-------------------- 560
Query: 644 KKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGP 703
Q+ P L L PP P + P P S +G GP
Sbjct: 561 ----QAPPV-----LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611
Query: 704 PPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFS 763
PP P PS+ G + G + + TP + G+ GP +
Sbjct: 612 PP------------PPSRSPSS----TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 655
Query: 764 NP----------HEPWNR------LHRTPPSFPTP-PPWLKPGELE 792
+P W+R R P P P PP PG +
Sbjct: 656 SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 701
Score = 65.5 bits (158), Expect = 3e-10
Identities = 128/508 (25%), Positives = 172/508 (33%), Gaps = 73/508 (14%)
Query: 27 RGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEED 86
R L A G GGA + A + S + P S P+ R R ++TS
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPV 114
Query: 87 IIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPH 146
G A + +K + + +E V + + KR AL+ G + P
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKAT-EAPKRSALSAGARRDTSGPTPGTPS 173
Query: 147 HYSSDRENDRNLCQHLGKRKKMPKAL-RQLKPGQNSCRDSDSESASGESK---------- 195
+ R R +G + P A R G S SE ++ E
Sbjct: 174 PAMARRS--RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 196 -GFHRSSSRERLSDS--------SAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVN 246
G R +SR S + S PS+ GT S + K A
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP--QVTPPR 289
Query: 247 KDPELGVGTLPEHDSQDAGPIVPKISG----LERSQEKSQDCCKEPIFEPVVLKDPCPQV 302
KD +G L P S L + S C+ + P+ L P P
Sbjct: 290 KDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ--LATPLPLAPPSPSA 347
Query: 303 A---QPIPQPQTEPQLRAPSP--DPDLVQRTEAPPQPP--PLSTQPPQGPPEAQLQP--- 352
Q +P P P +A + P L P PP PL+T PPQ PP L P
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407
Query: 353 APQPQVQRP------PRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSS 406
P P P P PQ+P L L + P + + P S S +S
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS------ 461
Query: 407 SRSSTPAKTQP--APPHISHHP-SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPP 463
P+ T P APP ++ P P P + P SP S TP Q P P + APP
Sbjct: 462 -----PSATPPSQAPPSLAAPPLQVPPSPPASPPMSP--SATPPPQAP-----PPLAAPP 509
Query: 464 TALPPPPP-----LTSGSLQVAGHPAGS 486
L PPP L + LQ P S
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPSPPAS 537
Score = 53.1 bits (126), Expect = 2e-06
Identities = 72/246 (29%), Positives = 94/246 (38%), Gaps = 59/246 (23%)
Query: 298 PCPQVAQPI----PQPQTEPQLRAPS----PDPDLVQRTEAPPQPP------PLSTQPPQ 343
P P A P+ P PQ P L P P P +AP P PL+T PPQ
Sbjct: 502 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 561
Query: 344 GPPEA-----QLQPAP--QPQVQRPPRPQSP-----------TQLLHQNLPPVQAHPSAQ 385
PP Q+ P+P P +Q P RP +P T L PP + +
Sbjct: 562 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 621
Query: 386 SLSQP-LSAYNSSSLS----LNSLSSSRSSTPAKTQPAPPHISH-HPSA---SPFPLSLP 436
+LS P L+ ++SS+ S L S A + P ++ HP+A P P
Sbjct: 622 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 681
Query: 437 NHSPLHSFTPTLQPPA-------------HSHHPNMFAP-PTALPP-PPPLTSGSLQVAG 481
+P P PPA + P P P AL P P P TSG AG
Sbjct: 682 RGAP---GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAG 738
Query: 482 HPAGST 487
AG++
Sbjct: 739 AGAGAS 744
Score = 51.2 bits (121), Expect = 6e-06
Identities = 84/339 (24%), Positives = 120/339 (35%), Gaps = 53/339 (15%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQ--PPQGPPEAQLQPAPQ 355
P P +A+ TE L P+P TE P + +++ + P A+ +P+
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 356 PQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQ-PLSAYNSSSLSLNSLSSSRSSTPAK 414
+QRP +S + P ++ PSA+ + P L +L + + P K
Sbjct: 232 GGLQRPAS-RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 415 -TQPAPPHISHHPSASPFP-LSLPNHSPLHSFTPTLQPPAHSHHPN-MFAPPTALPPPPP 471
PA +S P A+P P +L + +P PTL HS A P L PP P
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAP-----PTLPATPHSSSLTCQLATPLPLAPPSP 345
Query: 472 LTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQH 531
SLQ P + S+ T L S + S P P L
Sbjct: 346 SAPPSLQTLPSPPATPPSQA--------TTSLGSPTLQATHSFLPSPPLSP--------- 388
Query: 532 QHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGI- 590
TP P A P A+ P APP P + P S P A + +
Sbjct: 389 ----------LATPPPQAPPALALPPLQAPPSPPASP-PLSPLATPS-----PQAPNALA 432
Query: 591 -----PPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGK 624
P PP P +Q F P + P P P +
Sbjct: 433 VHLLQAPFSPPPSP--PVQAPFSPPASPPVSPSATPPSQ 469
Score = 34.7 bits (78), Expect = 0.58
Identities = 71/320 (22%), Positives = 110/320 (34%), Gaps = 59/320 (18%)
Query: 696 PTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKD 755
P G+P PPP + PAA + A GG P P +
Sbjct: 29 PPGSPRPPPP-----VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
Query: 756 GPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSK 815
G S +N ++ R R PP+ T PG + A+ R + ++ +S
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNT-----SPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 816 DD-----KERESVEK--------RHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEARE 862
++ K E+ ++ R +S P+P P A + TE
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV--------GLP 190
Query: 863 KDKPKERERDHSES-RKDLA-ADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYV 920
+ P R R +E RK ++ A EH E AA + P
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTE-----------PSPAARRRPSAGGGLQRPAS 239
Query: 921 RTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASE 980
R+ + SA P S+ +R +G P P S+ K P+ Q R +
Sbjct: 240 RS-LSSSATPLSSPARSGPSARGTP--RAPAHPSQPK------------PKGLQALRPPQ 284
Query: 981 PPPPNSSSSVHPGPLASMPM 1000
PP ++ GPL+S P+
Sbjct: 285 VTPPRKDAAPALGPLSSSPL 304
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 66.2 bits (160), Expect = 2e-10
Identities = 186/802 (23%), Positives = 281/802 (35%), Gaps = 181/802 (22%)
Query: 292 PVVLKDPCPQ----VAQPIP----QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST---- 339
PV+ P PQ V+ P+P QPQ + +AP+P + P P L++
Sbjct: 617 PVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEK 676
Query: 340 ----QPPQGPPEAQLQP------APQPQVQRPPRPQSPTQLLHQNLPP---VQAHPSAQS 386
QPP P A L PQ + Q+P + P H ++P V A P AQ
Sbjct: 677 IVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGP----HLSVPASVIVSAPPPAQD 732
Query: 387 LSQPLSAYNSSSLSLNSLSSSRSSTPAKTQP-APPHISHHPSASPFPLSLPNHSPL---- 441
+ + L + S S PA P A P PS+SP SLP+ +PL
Sbjct: 733 PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSP---SLPHQAPLGDSP 789
Query: 442 -----HSFTPTLQPPAHSHHPNMFAPPTALPP----PPPLTSGSLQVAGHPAGSTYSEQD 492
H P +PP+ P + P + PP PPP A T
Sbjct: 790 HLPSPHPTRPPSRPPS---RPQSVSRPPSEPPLHPCPPP-----------QAPPTLPGIF 835
Query: 493 ILRQELNTRFLASQSADRGASLGPP-PYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIP 551
+++ +L AS A + GPP P LR + + T + +
Sbjct: 836 VIQNQLGVPPPASNPAP--TAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSE 893
Query: 552 PTAIMPTPAPPMFD-KYPTKVDPFYRHSLFHSYPPAVSGIP-PMIPPTGPFGSLQGAFQP 609
++ +P P P F ++P P + PP + +P P PP P + Q
Sbjct: 894 TSSRLPAPTPSDFQLQFPPSQGPHKS----PTPPPTLHLVPEPAAPPPPPPRTFQ----- 944
Query: 610 KLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFG--LKPEFLSRPP 667
+T PF P L +P K + H++ G L+ + P
Sbjct: 945 MVTTPF-PALPQP----------------------KALLERFHQVPSGIILQNKAGGAPA 981
Query: 668 GPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFT 727
P ++ L P+ +G A P+GTP P + A L P P+
Sbjct: 982 APQTSTSL---GPLTSPAASVLVSGQA-PSGTPTAPSHAPAPAPMAATGLPPL-LPAENK 1036
Query: 728 GLAA------VGGNAFGGLGNPS--VTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTP--- 776
A+ V A G G PS + + G K P++Q S LH+
Sbjct: 1037 AFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQP-SKEACFLEHLHKHQGSV 1095
Query: 777 ---------PSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRH 827
PSF L P + + A + D + VD+ +VS + KR
Sbjct: 1096 LHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHK-VDEEFETVS------TQLLKRT 1148
Query: 828 SSHPSPAPVLPVNALGHTRSSTEQ-------IRAHLNTEAREKDKPKERERDHSESRKDL 880
+ + +L + S E I+ T A +K KE+ ++ S + L
Sbjct: 1149 QAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSL 1208
Query: 881 AADEHKAKEGH-LPEKDGHGH-EGRAAGEEAKQLARVP------------SPYVRTPVVE 926
+ EGH LP GHG A G + +P SP V
Sbjct: 1209 GLPIAASSEGHRLP---GHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARAS 1265
Query: 927 SARPNSTSSREAE-----------PRKGEPAYENPKKSSEVKVKEERKEDHDL------- 968
S+ +S+SS A P + P + + S + +K + K++ L
Sbjct: 1266 SSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNT 1325
Query: 969 -------PPEAPQTHRASEPPP 983
PP P T + +EPPP
Sbjct: 1326 ALDPVHQPPPPPATLKVAEPPP 1347
Score = 56.2 bits (134), Expect = 2e-07
Identities = 129/499 (25%), Positives = 175/499 (35%), Gaps = 85/499 (17%)
Query: 309 PQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPT 368
P T QL A +P L + A P P G A + A QV +P Q P
Sbjct: 503 PHTGGQLIA---NPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPV 559
Query: 369 QLLHQNLP----PVQAHPSAQSLSQPLSAYNSSSLSLNSLSSS-RSSTPAK-TQPAPPHI 422
L +LP P A P+A ++ Q ++ S+ LN+ + +TPA T A P +
Sbjct: 560 SLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVL 619
Query: 423 SHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP---LTSGSLQV 479
+ P A P ++ PL P Q P + P APP A P P +S V
Sbjct: 620 TVQP-APQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIV 678
Query: 480 AGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTH 539
G P +T + IL Q+ FL + + + S P H
Sbjct: 679 LGQPPSATPTA--ILTQDSLQMFLPQERSQQPLSAEGP---------------------H 715
Query: 540 QHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYP-PAVSGIPPMIPPTG 598
+ PP A P PA P+ + P S P P + P+ P G
Sbjct: 716 LSVPASVIVSAPPPAQDPAPATPV--AKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP-G 772
Query: 599 PFGSLQGAFQPKLTD--------PFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSD 650
P S Q L D P RP R P + Q V +
Sbjct: 773 PSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSR---------------PQSVSRPPSEP 817
Query: 651 P-HKLDFGLKPEFLSRPPGPSLF---GAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPH 706
P H P + P P +F + P + P+ +A G P P PP
Sbjct: 818 PLHPC-----PPPQAPPTLPGIFVIQNQLGVPPPASNPAP--TAPGPPQPPLRPQSQPPE 870
Query: 707 HSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPH 766
L PA HL P + S AV ++ P+ TP S F + PS +P
Sbjct: 871 GP--LPPAPHLPPSSTSS------AVASSSETSSRLPAPTP-SDFQLQFPPSQGPHKSPT 921
Query: 767 EPWNRLHRTP-PSFPTPPP 784
P LH P P+ P PPP
Sbjct: 922 PP-PTLHLVPEPAAPPPPP 939
Score = 49.3 bits (116), Expect = 2e-05
Identities = 81/319 (25%), Positives = 111/319 (34%), Gaps = 92/319 (28%)
Query: 200 SSSRERLSDSSAPSSLGTGY--------FCDSDSDQEEKASDASSEKLFNTVIVNKDPEL 251
+SS E++ PS+ T F + Q+ +++ + +VIV+ P
Sbjct: 671 ASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPP- 729
Query: 252 GVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVV-----LKDPCPQVAQPI 306
+QD P P G + + D P P + LK P P + +
Sbjct: 730 ---------AQDPAPATPVAKGAGLGPQ-APDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779
Query: 307 PQ----------PQTEPQLRAPSPDPDLVQRTEAPPQPPPLST-QPPQGPP--------E 347
P P P R PS P Q PP PPL PPQ PP +
Sbjct: 780 PHQAPLGDSPHLPSPHPT-RPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQ 838
Query: 348 AQL-------QPAP------QPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAY 394
QL PAP QP ++ P+ Q P LPP P
Sbjct: 839 NQLGVPPPASNPAPTAPGPPQPPLR--PQSQPP----EGPLPPAPHLPP----------- 881
Query: 395 NSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHS 454
+S+S ++ S S + S PA P+ S F L P H +PT P H
Sbjct: 882 SSTSSAVASSSETSSRLPA------------PTPSDFQLQFPPSQGPHK-SPTPPPTLH- 927
Query: 455 HHPNMFAPPTALPPPPPLT 473
+ P A PPPPP T
Sbjct: 928 ----LVPEPAAPPPPPPRT 942
Score = 42.4 bits (98), Expect = 0.003
Identities = 143/624 (22%), Positives = 191/624 (30%), Gaps = 166/624 (26%)
Query: 305 PIPQPQTEPQLRAPS-------PDPDLV-QRTEAPPQPPPLSTQPPQ---------GPPE 347
P P +P AP P P+++ RT P QP P PP+ P
Sbjct: 316 PTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAG 375
Query: 348 AQL--QPAPQPQVQRPPRPQS------------------PTQLLHQNL---PPVQAHPSA 384
A L Q P Q+P PQ+ P L N+ PP +A
Sbjct: 376 ATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAA 435
Query: 385 Q-----SLSQPLSAY---NSSSLSLNS-------------------LSSSRSSTPAKT-- 415
+LS+P+S + SS+ + + L S+ PA
Sbjct: 436 PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGG 495
Query: 416 ---QPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQP--PAHSHH-----PNMFAPPTA 465
A PH A+P + PL S P L P AHS H P P
Sbjct: 496 QILAAAAPHTGGQLIANPILTNQNLAGPL-SLGPVLAPHSGAHSAHILSAAPIQVGQPAL 554
Query: 466 LPPPPPLTSGSLQVAGHPAGSTYSEQDILR---------QELNTRFLASQSADRGASLG- 515
P L +GSL PA + + +L+ LNT Q A A+ G
Sbjct: 555 FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE 614
Query: 516 ------------PPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPH-AIPPTAIMPTPAPP 562
PP + T Q Q Q P P A PP A P P+P
Sbjct: 615 AAPVLTVQPAPQAPPAVSTPLPLGLQQPQ-----AQQPPQAPTPQAAAPPQATTPQPSPG 669
Query: 563 MFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKP 622
+ P K+ V G PP PT Q + Q F P R
Sbjct: 670 LASS-PEKI---------------VLGQPPSATPTAIL--TQDSLQ-----MFLPQERSQ 706
Query: 623 GKWCAMHVHI---AWQIYHHQQKVKKQMQSDPHKLDFGLKPEF----LSRPPGPSLFGA- 674
A H+ A I + + P GL P+ S P P + A
Sbjct: 707 QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAA 766
Query: 675 -IHHPHDLARPSTLFSA-------AGAAHPTGTPFGPPPHHSNFLNPAAH-----LEPFN 721
+ P + PS A + HPT P PP + P + P
Sbjct: 767 PLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQ 826
Query: 722 RPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPT 781
P T G+ + LG P N P +P R PP P
Sbjct: 827 APPTLPGIFVIQNQ----LGVPPPASN---------PAPTAPGPPQPPLRPQSQPPEGPL 873
Query: 782 PP-PWLKPGELERSASAAAHDRDR 804
PP P L P + ++++ R
Sbjct: 874 PPAPHLPPSSTSSAVASSSETSSR 897
Score = 38.5 bits (88), Expect = 0.040
Identities = 50/186 (26%), Positives = 69/186 (37%), Gaps = 23/186 (12%)
Query: 312 EPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLL 371
+ QL PD + V + + P S++ + P L + +PP P PT+L
Sbjct: 1190 DKQLAKEKPD-EYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPP-PHLPTKL- 1246
Query: 372 HQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAP------PHISHH 425
V H A A SSSLS +S SSS +S+ + P P I +
Sbjct: 1247 ------VIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTY 1300
Query: 426 PSASPFPLSLPNHSP------LHS--FTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSL 477
+ S L L +H+ P QPP + PP PPPPP T
Sbjct: 1301 EARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMN 1360
Query: 478 QVAGHP 483
HP
Sbjct: 1361 GTVDHP 1366
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 65.5 bits (158), Expect = 3e-10
Identities = 93/388 (23%), Positives = 142/388 (36%), Gaps = 91/388 (23%)
Query: 275 ERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTE---PQLRAPSPDPDLVQRTEAP 331
++ Q++ Q +P + ++ P P +Q +PQ + Q P P P
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ-------- 306
Query: 332 PQPPPLSTQPPQGPPEAQLQP-----------------------APQPQVQRPPRPQSPT 368
QPP QP Q PP++Q QP AP Q P +PQ
Sbjct: 307 -QPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQ--- 362
Query: 369 QLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSA 428
+ Q VQ +AQ ++ + SS L+S S + ++ P PP S P
Sbjct: 363 --VQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQ 420
Query: 429 SPFPLSLPNH--------SPLHSFTPTLQP-----PAHSHHPNMFAPPTALPPPPPLTSG 475
P S PN SP SF P+ P P + P F+ P+ P P+
Sbjct: 421 ---PSSQPNSNVSSGPAPSP-SSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPS 476
Query: 476 SLQVAGHPAGSTYSEQ--------------DILRQELNTRFLASQSADRGASLG------ 515
S+ PAGS+ +E+ + LR+ +N ++ DR L
Sbjct: 477 SVM---SPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINK---IDKNEDRKKDLSKMKSLL 530
Query: 516 ---PPPYLRTEFHQHQHQHQHTHQHTHQHTF-TPFPHAIPPTAIMPTPAPPMFDKYPTKV 571
P R Q + + TP P +PPT P+ D +
Sbjct: 531 DILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTK-QQYLCQPLLDAVLANI 589
Query: 572 -DPFYRHSLFHSYPPAVSGI--PPMIPP 596
P + HSL+ ++ PA++ I PP+ P
Sbjct: 590 RSPVFNHSLYRTFVPAMTAIHGPPITAP 617
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 65.5 bits (158), Expect = 3e-10
Identities = 105/462 (22%), Positives = 158/462 (34%), Gaps = 91/462 (19%)
Query: 12 KKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPR 71
+ RRSRS R RRS L SSS S + PP P R
Sbjct: 337 RHRRSRSPVRRRRRSSASLSG-----------------SSSSSSSSRSRSPPKKPPKRTS 379
Query: 72 -PPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTK--KKREA 128
PPR+ RR S SA P R + P T K R +
Sbjct: 380 SPPRKTRRLSPSAS-------------------------PPRRRHRPSPPATPPPKTRHS 414
Query: 129 LTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSE 188
T S ++KSR+S S + +H G K+ + KP + +S+ E
Sbjct: 415 PTPQQSNRTRKSRVS-----VSPGRTSGKVTKHKGTEKRESPSPAP-KPRKVELSESE-E 467
Query: 189 SASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKD 248
G+ R + + SS +G S+ ++ +++ + E
Sbjct: 468 DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE----------- 516
Query: 249 PELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQ 308
VG H + P+ E S + P P + P A P +
Sbjct: 517 ----VGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP---PPTRRRRSPSPAPPPRR 569
Query: 309 ---PQTEPQLRAPSPDPDL-----------VQRTEAPPQPPPLSTQPPQGPPEAQLQPAP 354
P P+ R PSP P +QR +P PP T P PP+ + P+P
Sbjct: 570 RRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP 629
Query: 355 QPQ---VQRPPRPQSPTQLLHQNLPPVQA-HPSAQSLSQPLSAYNSSSLSLNSLSSSRSS 410
P+ PP Q + + + P + + H S S+ S + S R
Sbjct: 630 PPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 689
Query: 411 TPAKTQPAPPHISHHPSASPFPLSLPNHS--PLHSFTPTLQP 450
P +T +PP + S+SP P+ S P+ + T +P
Sbjct: 690 AP-QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730
Score = 58.5 bits (140), Expect = 4e-08
Identities = 111/461 (24%), Positives = 166/461 (36%), Gaps = 45/461 (9%)
Query: 52 SGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQ 111
S S + + S +PS RP RR R S S + + P
Sbjct: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPR--RMPPP 335
Query: 112 ERVEKRQTPLTKKKR-EALTNGLSFHSKKSR-----LSHPHHYSSDRENDRNLCQHLGKR 165
R + ++P+ +++R A +G S S SR P SS R L
Sbjct: 336 PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP 395
Query: 166 KKM----------PKALRQLKPGQ-NSCRDSDSESASGESKG--FHRSSSRERLSDSSAP 212
++ PK P Q N R S + G + G + +R S S AP
Sbjct: 396 RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAP 455
Query: 213 SSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKIS 272
+S+ D+ K + A S + ++ + + S+D P
Sbjct: 456 KPRKV-ELSESEEDKGGKMAAADSVQQ-RRQYRRQNQQSSSDSGSSSSSEDERP------ 507
Query: 273 GLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPP 332
+RS K+ + + P P P+ Q P+ + R+PSP P +R+ + P
Sbjct: 508 --KRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGR-RRRSPSPPPTRRRRSPS-P 563
Query: 333 QPPPLSTQPPQGPPEAQL-QPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPL 391
PPP + P PP + P P+ + P R P Q + PP P ++ S P
Sbjct: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP----PKRRTASPPP 619
Query: 392 SAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPL--SLPNHSPLHSFTPTLQ 449
+S S S P K + +P PS S S P+ S + +P Q
Sbjct: 620 PPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP--Q 677
Query: 450 P-PAHSHHPNMFAPPTALPPPPPL--TSGSLQVAGHPAGST 487
P HS P AP T+ PPP S S Q P+ ST
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST 718
Score = 50.8 bits (120), Expect = 8e-06
Identities = 172/849 (20%), Positives = 272/849 (32%), Gaps = 168/849 (19%)
Query: 162 LGKRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFC 221
L K + + + Q K +D D + E K SSRE+ S +P
Sbjct: 126 LKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEK----ESSREKRERSRSP--------- 172
Query: 222 DSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS 281
+ K+ S + + V ++ + P H ++ P P E++ E
Sbjct: 173 -----RRRKSRSPSPRRRSSPV--RRERKRSHSRSPRHRTKSRSPS-PAPEKKEKTPELP 224
Query: 282 QDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPP------ 335
+ K + EP V + +P+P+ P+ + PSP+ + + E P
Sbjct: 225 EPSVK--VKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS 282
Query: 336 ----------PLSTQPPQG--PPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPS 383
P T+P + P +P +R P P+ T + +PP H
Sbjct: 283 KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTP--PRRMPPPPRHRR 340
Query: 384 AQSLSQPLSAYNSSSLSLN----SLSSSRSSTPAKTQP-----------------APPHI 422
++S P+ SS SL+ S SSSRS +P K P +PP
Sbjct: 341 SRS---PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR 397
Query: 423 SHHPSASPFPLSLPNHSPLH-----------SFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
H PS P HSP S +P + H + P P P
Sbjct: 398 RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457
Query: 472 LTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQ-SADRGASLGPPPYLRTEFHQHQHQ 530
L + G + D ++Q R Q S+D G+S H +
Sbjct: 458 -RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE 516
Query: 531 HQHTHQHTHQHTFTPFP-----HAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPP 585
+H+ + +P P P +P+PP PT+ R S + PP
Sbjct: 517 VGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPP-----PTR----RRRSPSPAPPP 567
Query: 586 AVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKK 645
P PP P+ P P R+ I + Y K+
Sbjct: 568 RRRRTP--TPP------------PRRRTPSPPPRRRSPSPRRYSPPIQ-RRYSPSPPPKR 612
Query: 646 QMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFS----AAGAAHPTGTPF 701
+ S P P+ + P P H P R S + + + H G+
Sbjct: 613 RTASPPP------PPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSP 666
Query: 702 GPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQN 761
+ P P RP S P G P +
Sbjct: 667 SRSTREARSPQPNKRHSPSPRPR--------------APQTSSSPPPVRRGASSSPQRRQ 712
Query: 762 FSNPH-EPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKER 820
+P P R+ RTP +P +++++AS + R R S S
Sbjct: 713 SPSPSTRPIRRVSRTP----------EPKKIKKAASPSPQSVRRVSSSRSVSGSP----- 757
Query: 821 ESVEKRHSSHPSP----------APVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERE 870
E K+ + PSP +P +PV S R + + E K K K+++
Sbjct: 758 EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR-NSDQEGGGKKKKKKKD 816
Query: 871 RDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARP 930
+ H + +K HK + H EK AA +A + + V + P
Sbjct: 817 KKHKKDKK------HKKHKKHKKEKAVAA--AAAAAVTPAAIAAATTTLAQEEPVAAPEP 868
Query: 931 NSTSSREAE 939
+ EAE
Sbjct: 869 KKETESEAE 877
Score = 48.1 bits (113), Expect = 5e-05
Identities = 50/227 (22%), Positives = 83/227 (36%), Gaps = 33/227 (14%)
Query: 786 LKPGELERSASAAAHDRDRDVDKRDSSVSKDDKER----ESVEKRHSSHPSP----APVL 837
+K ++E+ A+ +D D DKRD + +E+ S +R S PSP +PV
Sbjct: 131 IKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVR 190
Query: 838 PVNALGHTRSSTEQIRAHLNTEAREK-------DKPKERERDHSESRKDLAADEHKA-KE 889
H+RS + ++ + A EK +P + ++ S +D K K
Sbjct: 191 RERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKP 250
Query: 890 GHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYEN 949
+PE E + E+ K+ R R S S + R P++
Sbjct: 251 EPIPEPKEPSPEKNSKKEKEKEKTR-------------PRSRSRSKSRSRTRSRSPSHTR 297
Query: 950 PKKSSEVKVKEERKEDHDLPPEAPQTHRASE----PPPPNSSSSVHP 992
P++ + + P P R + PPPP S P
Sbjct: 298 PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSP 344
Score = 44.7 bits (104), Expect = 6e-04
Identities = 66/320 (20%), Positives = 107/320 (33%), Gaps = 50/320 (15%)
Query: 703 PPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGP---SV 759
PPP H +P R S+ A++ G++ + S +P +
Sbjct: 334 PPPRHRRSRSPVRR----RRRSS----ASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT 385
Query: 760 QNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKE 819
+ S P R HR P TPPP + + ++ R V S +
Sbjct: 386 RRLSPSASPPRRRHRPSPP-ATPPPKTRHSPTPQQSNRTRKSR---VSVSPGRTSGKVTK 441
Query: 820 RESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKD 879
+ EKR S PSPAP L + A ++ + + ++ ++ S+S
Sbjct: 442 HKGTEKRES--PSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSS 499
Query: 880 LAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAE 939
++++ + K H+ +G GR + A PSP R + P R
Sbjct: 500 SSSEDERPKRSHVK----NGEVGRRRRHSPSRSAS-PSPRKRQ---KETSPRGRRRRSPS 551
Query: 940 P----RKGEPAYENPKKSSEVKVKEERKEDHDLPPEA---------------------PQ 974
P R+ P+ P + R+ PP P+
Sbjct: 552 PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPK 611
Query: 975 THRASEPPPPNSSSSVHPGP 994
AS PPPP +S P P
Sbjct: 612 RRTASPPPPPKRRASPSPPP 631
Score = 38.5 bits (88), Expect = 0.040
Identities = 51/234 (21%), Positives = 86/234 (36%), Gaps = 27/234 (11%)
Query: 774 RTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSP 833
R+PP P P + R + +A+ R R ++ + + ++ + + S
Sbjct: 368 RSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSR 427
Query: 834 APVLPVNALGHTRSSTEQIRAHLNTEAREKDKP--KERERDHSESRKD-----LAADE-H 885
V P G ++ H TE RE P K R+ + SES +D AAD
Sbjct: 428 VSVSPGRTSG-------KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ 480
Query: 886 KAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEP 945
+ ++ + G ++ E ++ R +V+ V R +S S R A P
Sbjct: 481 QRRQYRRQNQQSSSDSGSSSSSEDERPKR---SHVKNGEVGRRRRHSPS-RSASP----- 531
Query: 946 AYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMP 999
+P+K + R+ PP + S PPP + P P P
Sbjct: 532 ---SPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTP 582
Score = 33.9 bits (76), Expect = 0.99
Identities = 58/285 (20%), Positives = 91/285 (31%), Gaps = 34/285 (11%)
Query: 744 SVTPNSMFGHKD-GPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDR 802
S +P+ K+ P + +P P R R+P P P P R + + R
Sbjct: 528 SASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR 587
Query: 803 DRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEARE 862
R R S +++R+S PSP P + T A
Sbjct: 588 RRSPSPRRYS--------PPIQRRYS--PSPPP----------KRRTASPPPPPKRRASP 627
Query: 863 KDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQ----LARVPSP 918
PK R HS K ++ K + L K G + EA+ PSP
Sbjct: 628 SPPPKRRV-SHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSP 686
Query: 919 YVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHR- 977
R P S+ P + P++ + + + V E K+ +PQ+ R
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR 746
Query: 978 -------ASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISS 1015
+ P P P P+ S + + P+ S
Sbjct: 747 VSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 64.7 bits (156), Expect = 5e-10
Identities = 69/235 (29%), Positives = 91/235 (38%), Gaps = 44/235 (18%)
Query: 256 LPEHDSQDAGPIVP---KISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTE 312
LP + AG P K S + R Q SQ + K P P V Q +
Sbjct: 649 LPSQSAPSAGSAAPMFVKYSTITRLQNASQH-------SGALFKPPTPPVMQ---SQSVK 698
Query: 313 PQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAP----QPQVQRPPRPQSPT 368
PQ+ P P+ V PP PPP G AQL+PAP PQ PP P
Sbjct: 699 PQILVP---PNGVVPPPPPPPPPPTP-----GSAMAQLKPAPCAPSLPQFSAPPPPLKIH 750
Query: 369 QLLH--QNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHP 426
Q+ H Q PP P P A +++ + +S+++ P TQ APP
Sbjct: 751 QVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP------ 804
Query: 427 SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPT--------ALPPPPPLT 473
+P P +P +F + PP+ P PPT A PPP PL+
Sbjct: 805 --TPTP-PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS 856
Score = 61.2 bits (147), Expect = 6e-09
Identities = 58/224 (25%), Positives = 83/224 (37%), Gaps = 32/224 (14%)
Query: 286 KEPIFEPVVLKDPCPQVAQPIPQPQ--------TEPQLRAPSPDPDLVQRTEA----PPQ 333
K+P F + P P+P P +P SP P +V++ + PP
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT 874
Query: 334 PPPLSTQP---------PQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNL----PPVQA 380
PP + +QP PQ PP + +P QP P P P +L PP
Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP 934
Query: 381 HPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA--KTQPAPPHISHHPSASPFPLSLPNH 438
P+ P ++ +S++S+P K P P S S+S P
Sbjct: 935 VPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKR 994
Query: 439 SPLHSFTPTLQPPAHSHHPNM-FAPPTALPPPPPLTSGSLQVAG 481
+ S PPA S P+ PP A PP P G L ++G
Sbjct: 995 PSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP----GKLNLSG 1034
Score = 59.7 bits (143), Expect = 2e-08
Identities = 175/757 (23%), Positives = 225/757 (29%), Gaps = 172/757 (22%)
Query: 274 LERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQ 333
LE S + + P V P P++ P Q P L P P P PP
Sbjct: 587 LEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP--------PPP 638
Query: 334 PPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSA 393
PPP PP PP Q AP P + T QN H A
Sbjct: 639 PPP----PPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQN---ASQHSGALFKPPTPPV 691
Query: 394 YNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAH 453
S S+ L P P PP A P P S P PP
Sbjct: 692 MQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPP---PPLK 748
Query: 454 SH---HPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADR 510
H H APPT PPPPP+ + L Q+ +
Sbjct: 749 IHQVQHITQVAPPTP-PPPPPIPAP---------------------------LPPQAPPK 780
Query: 511 GASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTK 570
P P T T P + A PTP PP+ P K
Sbjct: 781 PLVTIPAP-------------------TSTKTVAP----VVTQAAPPTPTPPV---PPAK 814
Query: 571 VDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHV 630
P + S PP P+ PPT P Q +F K P P+ P ++
Sbjct: 815 KQPAFPASYIPPSPPTPP--VPVPPPTLP---KQQSFCAK--PPPSPLSPVP----SVVK 863
Query: 631 HIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSA 690
IA Q M+S P K P P+ P A+P S+
Sbjct: 864 QIASQF--PPPPTPPAMESQPLK-------------PVPANVAPQSPPAVKAKPKWQPSS 908
Query: 691 AGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSM 750
P F PPP S+ + P P P P P +
Sbjct: 909 IPVPSP---DFPPPPPESSLVFPPPPPSPVPAPP------------------PPPPPTA- 946
Query: 751 FGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRD 810
P+ +P + ++ + P PPP + +S+S A H + D
Sbjct: 947 -----SPTPDKSGSPGKKTSK--TSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKR-PSVD 998
Query: 811 SSVSKDDKERESVEKRHSSHPSP-APVLP-------VNALGHTRSSTEQIRAHLNTEARE 862
S VSK ES + P P AP P VN G + +A + R
Sbjct: 999 SLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPV-LSGRG 1057
Query: 863 KDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYV-- 920
KD E S+S D E LP L + P V
Sbjct: 1058 KDSVVEFPSPPSDS--DFPP---PPPETELP------------------LPPIEIPAVFS 1094
Query: 921 --RTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRA 978
+P V P + +K P + S + E E + PQ
Sbjct: 1095 GNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQV--- 1151
Query: 979 SEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISS 1015
P P SS SV PG LA + T+ I S+SS
Sbjct: 1152 --PTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSS 1186
Score = 42.0 bits (97), Expect = 0.004
Identities = 58/261 (22%), Positives = 90/261 (34%), Gaps = 56/261 (21%)
Query: 255 TLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQ 314
T P +SQ P+ ++ K++ P ++P + P P P P E
Sbjct: 874 TPPAMESQPLKPVPANVAPQSPPAVKAK-----PKWQPSSIPVPSPD----FPPPPPESS 924
Query: 315 LRAPSPDPDLVQRTEAPPQPPPLSTQPP---QGPPEAQLQPAPQPQVQRPP--------- 362
L P P P V APP PPP + P G P + P ++PP
Sbjct: 925 LVFPPPPPSPVP---APPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSI 981
Query: 363 ---------RPQSPT--QLLHQNLPPVQA-HPSAQSLSQPLSAYNSSSLSLNSLS----- 405
P+ P+ L+ + PP ++ PS ++L P + L+L+ ++
Sbjct: 982 KSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVL 1041
Query: 406 ------------SSRSSTPAKTQPAPPHISHHPSASP-FPLSLPNHSPLHSFTPTLQPPA 452
S R P+PP S P P L LP F+ P
Sbjct: 1042 QQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKV 1101
Query: 453 H--SHHPNMFAPPTALPPPPP 471
+ P ++ + PPP
Sbjct: 1102 AVVNPQPQQWSKMSVKKAPPP 1122
Score = 37.0 bits (84), Expect = 0.12
Identities = 49/208 (23%), Positives = 79/208 (37%), Gaps = 17/208 (8%)
Query: 292 PVVLKDPCPQVAQPIPQPQTEPQL-RAPSPDPDLVQRTEAPPQPPP--LSTQPPQGPPEA 348
P VL+ C P+ + + + PSP D ++ PP PP L P + P
Sbjct: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSD----SDFPPPPPETELPLPPIEIPAVF 1093
Query: 349 QLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSR 408
+P+ V P +PQ +++ + PP P ++ A S ++ ++
Sbjct: 1094 SGNTSPKVAVVNP-QPQQWSKMSVKKAPP-PTRPKRNDSTRLTQAEISEQPTMATVVPQV 1151
Query: 409 SSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPP 468
++P + P + + S+ H L S +P A ALPP
Sbjct: 1152 PTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDD-------MALPP 1204
Query: 469 PPPLTSGSLQVAGHPAGSTYSEQDILRQ 496
PPP Q AG+ GS S LR+
Sbjct: 1205 PPPELLSDQQKAGY-GGSHISGYATLRR 1231
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 63.9 bits (154), Expect = 9e-10
Identities = 79/346 (22%), Positives = 127/346 (36%), Gaps = 38/346 (10%)
Query: 104 KDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLG 163
K +L + + TP KKK++ G S R SS ++ R+ +
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKK--SSKKKKHRSESESKK 226
Query: 164 KRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDS 223
++ + P + K + S S + + +S+ HRS+S +DS+ S
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTS----ADSA------------S 270
Query: 224 DSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKS-- 281
SD S +++ K T + + P G E D+ + P G +Q S
Sbjct: 271 SSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEP------GTTSTQRPSSP 324
Query: 282 QDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQP 341
+ K+P P KD + + E PSP P+ PP P PL +
Sbjct: 325 ETATKQPS-SPYEDKD----------KDKKEKSATRPSPSPERSSTGPEPPAPTPLLAER 373
Query: 342 PQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSL 401
G P+ + PP SPT+ P + S+ S S P S + +S
Sbjct: 374 HGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP-QPTKVSR 432
Query: 402 NSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPT 447
++ SS S PA + IS P++ HS TP+
Sbjct: 433 HASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPS 478
Score = 57.0 bits (136), Expect = 1e-07
Identities = 216/1048 (20%), Positives = 327/1048 (31%), Gaps = 184/1048 (17%)
Query: 13 KRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAP----- 67
+RRSRS+ R R A G RT A S S + +G+ S P
Sbjct: 632 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGR 691
Query: 68 SRPRPPRRKRRESTS--------AEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQT 119
SR R PRR R S S + G + +S + K+ + Q R +
Sbjct: 692 SRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS-----SERKNKSRTSQRRSRSNSS 746
Query: 120 PLTKKKREALTNGLSFHSK----KSRLSHPHHYSSDRENDRNLCQHLGKRKK----MPKA 171
P KK R + S S KSRLS S + Q +R + PKA
Sbjct: 747 PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKA 806
Query: 172 LRQLKP--GQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEE 229
+ P ++S + + S+ H SSS S P G+ + E
Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS----ITSPQANE 862
Query: 230 KASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPI 289
++ F + + DPEL T H + P K S R Q S+ +P
Sbjct: 863 QSVTPQRRSCFES---SPDPELKSRTPSRHSCSGSSPPRVKSSTPPR-QSPSRSSSPQPK 918
Query: 290 FEPVVLKDPCPQVAQPIPQPQ------TEPQLRAPSP------------------DPDLV 325
+ ++ P P T + R+ SP PD
Sbjct: 919 VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTK 978
Query: 326 QRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQ 385
+ E PP+ + P +AQ P P + P PQ ++ +L VQ+ P +
Sbjct: 979 VKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSK---DSL--VQSCPGSL 1033
Query: 386 SLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFT 445
SL + + S +SS + ++T P H S + P +HS S
Sbjct: 1034 SLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP------DHRSDTSSPEVRQSHSESPSLQ 1087
Query: 446 PTLQPPAHSHHPNMFAPPTALPPPPPL--------TSGSLQVAGHPAGSTYSEQDILRQE 497
Q +P T L P+ S L+ P S +
Sbjct: 1088 SKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPT 1147
Query: 498 LNTRFLASQS----ADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQ-HTFTPFPHAIPP 552
+++ L QS A+ + PP Q T Q F+PFP
Sbjct: 1148 VDSNSLLGQSRLETAESKEKMALPP-----------QEDATASPPRQKDKFSPFP----- 1191
Query: 553 TAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLT 612
+ P + K + P R S P +P + L + K
Sbjct: 1192 --VQDRPESSLVFKDTLRTPPRERSGAGSS--PETKEQNSALPTSSQDEELMEVVE-KSE 1246
Query: 613 DPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLF 672
+P A QI H K+M + +F PE RP
Sbjct: 1247 EP------------------AGQILSHLSSELKEMSTS----NFESSPEVEERP------ 1278
Query: 673 GAIHHPHDLARPSTLFSAAGAAHPTGTPFGP--PPHHSNFLNPAAHLEPFNRPSTFTGLA 730
A+ D ++ A + GP P H N F P F
Sbjct: 1279 -AVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSG 1337
Query: 731 AVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGE 790
+G G + + +GP F N E T PS
Sbjct: 1338 PLGTEMNTGFS------SEVKEDLNGP----FLNQLE-------TDPSLDMK-------- 1372
Query: 791 LERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHS-SHP--SPAPVLPVNALGHTRS 847
E+S ++ H S +S D E+ + S S P P P + S
Sbjct: 1373 -EQSTRSSGHS--------SSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSAS 1423
Query: 848 STEQIRAHLNTEAREK---DKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRA 904
S E T +R P R+ + SR L+ K+ +P G
Sbjct: 1424 SPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD--IPRTPSRGRSECD 1481
Query: 905 AGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERK- 963
+ E K L + P P R+P S N+ R G + + K + + + +
Sbjct: 1482 SSPEPKALPQTPRPRSRSP--SSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRS 1539
Query: 964 ---EDHDLPPEAPQTHRASEPPPPNSSS 988
++ D+ P A R+ P+S +
Sbjct: 1540 GSSQELDVKPSASPQERSESDSSPDSKA 1567
Score = 55.8 bits (133), Expect = 2e-07
Identities = 117/520 (22%), Positives = 185/520 (35%), Gaps = 88/520 (16%)
Query: 6 RGHGLRKKRRSRS-QRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKE------- 57
R +++ RSRS QR RSR G + GR+ + S A+ S
Sbjct: 524 RSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGR 583
Query: 58 DNGKPPSSAPSRPRPP-RRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEK 116
+ P+ SR R P RR+ R T A + + P R +
Sbjct: 584 SRSRTPARRRSRSRTPTRRRSRSRTPARRG-----------------RSRSRTPARRRSR 626
Query: 117 RQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLK 176
++P+ ++ R + + S +SR P R R + R + P
Sbjct: 627 TRSPVRRRSR---SRSPARRSGRSRSRTPAR--RGRSRSRTPARRGRSRSRTPARRSGRS 681
Query: 177 PGQNSCRDSDSESAS---GESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASD 233
+ R S S + G S+ RS R S S P G S S E K
Sbjct: 682 RSRTPARRGRSRSRTPRRGRSRS--RSLVRRGRSHSRTPQRRGR-----SGSSSERKNKS 734
Query: 234 ASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPV 293
+S++ + N PE+ + S+ RS+ KS+ + +
Sbjct: 735 RTSQRRSRS---NSSPEMKKSRISSRRSRSLSS--------PRSKAKSRLSLRRSLSG-- 781
Query: 294 VLKDPCPQVAQPIPQPQT---EPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQL 350
PCP+ P ++ Q +A S P R+ + P PP ++ P +
Sbjct: 782 --SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP-PPKQKSKTPSRQSHSSS 838
Query: 351 QPAPQPQVQRPPRPQSPT--QLLHQNLPP-----VQAHPSAQSLSQPLSAYNSSSLSLNS 403
P P+ + PPR S T Q Q++ P ++ P + S+ S ++ S S
Sbjct: 839 SPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR 898
Query: 404 LSS--------SRSSTP---AKTQPAPPHISHHPSASPFPLSLPNH---------SPLHS 443
+ S SRSS+P K +P SH S+SP P + + SP +
Sbjct: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN 958
Query: 444 FTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHP 483
L P +SH + P PP S S ++ +P
Sbjct: 959 VESRLL-PRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP 997
Score = 45.4 bits (106), Expect = 3e-04
Identities = 67/280 (23%), Positives = 103/280 (36%), Gaps = 45/280 (16%)
Query: 765 PHEPWNRLHRTPPS-FPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESV 823
P +P++ + + S PTP K + +R + + R+ K+ S K E ES
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE-RKKSSKKKKHRSESESK 225
Query: 824 EKRHSSHPSPAPVLPVNALGHTRS-----STEQIRAHLNTEAREKDKPKERERDHSESRK 878
+++H P+P RS + + RAH +T A D + S SR
Sbjct: 226 KRKH-RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA---DSASSSDTSRSRSRS 281
Query: 879 DLAADEHKAKEGHLPE-KDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSRE 937
A A G P G EG A E P +TS++
Sbjct: 282 AAAKTHTTALAGRSPSPASGRRGEGDAPFSE---------------------PGTTSTQ- 319
Query: 938 AEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQ-THRASEPPPPN----SSSSVHP 992
P E A + P E K K+++++ P +P+ + EPP P P
Sbjct: 320 -RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSP 378
Query: 993 GPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLP 1032
PLA+ P++ P+N S TR +P LP
Sbjct: 379 QPLATTPLSQ-----EPVNPPSEASPTRDRSPPKSPEKLP 413
Score = 43.5 bits (101), Expect = 0.001
Identities = 73/354 (20%), Positives = 116/354 (32%), Gaps = 48/354 (13%)
Query: 20 RDRERRSRGGLGAGAAGGGGAGRTRALSLAS----------SSGSDKEDNGKPPSSAPSR 69
R RRSR G G G G +LS +S S G + D+ P + P
Sbjct: 1433 RTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQT 1492
Query: 70 PRPPRRK-------------RRESTSAEEDIIDGFAMTSFV-------TFEALEKDVALK 109
PRP R +RE + +E + + + + + L+ +
Sbjct: 1493 PRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS 1552
Query: 110 PQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMP 169
PQER E +P +K K S + S R + + K + P
Sbjct: 1553 PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAP 1612
Query: 170 KALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEE 229
+A S DS E + + R S S PS G+ ++S E
Sbjct: 1613 RA--------QSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS---STESSPEH 1661
Query: 230 KASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPI 289
++ + + + +P+ T P S + P + + + L R + +S E
Sbjct: 1662 PPKSRTARRGSRS---SPEPKTKSRTPPRRRSSRSSPELTRKARLSR-RSRSASSSPETR 1717
Query: 290 FEPVVLKDPCPQVAQPIPQPQTEPQLR---APSPDPDLVQRTEAPPQPPPLSTQ 340
P V+ P P ++ R A SP R P P P Q
Sbjct: 1718 SRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771
Score = 39.7 bits (91), Expect = 0.018
Identities = 30/85 (35%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 352 PAPQPQVQ--RPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRS 409
PAP+ V+ RPP P + + + S+ S S S+ +SSS S +S SSS S
Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Query: 410 STPAKTQPAPPHISHHPSASPFPLS 434
S+ + PA P P A P P S
Sbjct: 2644 SSSSSPSPAKP----GPQALPKPAS 2664
Score = 38.9 bits (89), Expect = 0.031
Identities = 75/341 (21%), Positives = 116/341 (34%), Gaps = 52/341 (15%)
Query: 268 VPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQR 327
VP+ ERS S +KD P+ + + P LR S P
Sbjct: 1410 VPRTPSRERSSSASSP----------EMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSL 1459
Query: 328 TEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRP-PRPQSPT--QLLHQNLPPVQAHPSA 384
+ + P + P +G E P P+ Q P PR +SP+ +L ++ L P + +
Sbjct: 1460 SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS 1519
Query: 385 QS-------------------LSQPLSAYNSSSLSLNSLSSSRSSTPAKTQP-------- 417
+S SQ L S+S S S S + AKT+
Sbjct: 1520 ESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS 1579
Query: 418 -APPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHS---HHPNMFAP-PTALPPPPPL 472
+ P + SP S SP P P A S P AP P ALP
Sbjct: 1580 GSSPEVDSKSRLSP-RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS 1638
Query: 473 TSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQ 532
S S P GS+ +E S++A RG+ P P ++ + +
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPP------KSRTARRGSRSSPEPKTKSRTPPRRRSSR 1692
Query: 533 HTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDP 573
+ + T + + + + + PP + P+ P
Sbjct: 1693 SSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP 1733
Score = 38.1 bits (87), Expect = 0.052
Identities = 42/199 (21%), Positives = 78/199 (39%), Gaps = 13/199 (6%)
Query: 348 AQLQPAPQPQVQRPPRPQ-SPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSS 406
+ L P+ ++R P P +P + + + PP + S S+ +SSS S +S SS
Sbjct: 2566 SSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS 2625
Query: 407 SRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTAL 466
S SS+ + + + S S+SP P + +P PP + P +L
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL 2685
Query: 467 PPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQ 526
L+ + E+ + + R S S++RG+ G R+ H+
Sbjct: 2686 RDSRSLSYSPV------------ERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHK 2733
Query: 527 HQHQHQHTHQHTHQHTFTP 545
+ + H+ + +P
Sbjct: 2734 RRRETPSPRPMRHRSSRSP 2752
Score = 37.4 bits (85), Expect = 0.089
Identities = 56/266 (21%), Positives = 83/266 (31%), Gaps = 31/266 (11%)
Query: 167 KMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSD 226
+ P AL L+P + S S S+S S SSS S SS+ S G+ +
Sbjct: 2516 QQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA 2575
Query: 227 QEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCK 286
+ S + K V + PE S + S S S
Sbjct: 2576 LKRVPSPTPAPK--EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633
Query: 287 EPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQP--PPLSTQPPQG 344
+ P PQ P+ +P P +R+ +P +P ++
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693
Query: 345 PPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSL 404
P + +P+PQP PR Q Q S+ S
Sbjct: 2694 SPVERRRPSPQPS----PRDQ-----------------------QSSSSERGSRRGQRGD 2726
Query: 405 SSSRSSTPAKTQPAPPHISHHPSASP 430
S S S + P+P + H S SP
Sbjct: 2727 SRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 36.2 bits (82), Expect = 0.20
Identities = 50/205 (24%), Positives = 76/205 (37%), Gaps = 33/205 (16%)
Query: 14 RRSRSQ-----RDRERRS-RGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPP---- 63
RRSRS +D+ R + R G+ ++ A RAL S SGS + G P
Sbjct: 1594 RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653
Query: 64 --SSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTP- 120
S+P P R RR S S+ E K + P R R +P
Sbjct: 1654 STESSPEHPPKSRTARRGSRSSPE-----------------PKTKSRTPPRRRSSRSSPE 1696
Query: 121 LTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQN 180
LT+K R + + + S ++R P + R + ++ + + R +
Sbjct: 1697 LTRKARLSRRSRSASSSPETRSRTPPRH---RRSPSVSSPEPAEKSRSSRRRRSASSPRT 1753
Query: 181 SCRDSDSESASGESKGFHRSSSRER 205
S S + +G RS SR R
Sbjct: 1754 KTTSRRGRSPSPKPRGLQRSRSRSR 1778
Score = 34.7 bits (78), Expect = 0.58
Identities = 38/213 (17%), Positives = 78/213 (36%), Gaps = 11/213 (5%)
Query: 793 RSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTRS---ST 849
RS R +R S S +++ +S + S + +P + + + RS S+
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSS 764
Query: 850 EQIRAHLNTEAREK---DKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAG 906
+ +A R P +++ + R+ + + P +
Sbjct: 765 PRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPK 824
Query: 907 EEAKQLARVP----SPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSS-EVKVKEE 961
+++K +R SP+ + R S +S +A + P + +SS + ++K
Sbjct: 825 QKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSR 884
Query: 962 RKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGP 994
H +P ++S PP + S S P P
Sbjct: 885 TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQP 917
Score = 33.5 bits (75), Expect = 1.3
Identities = 60/235 (25%), Positives = 83/235 (35%), Gaps = 44/235 (18%)
Query: 774 RTPP----SFPTPPPWLK---PGELERSASAAAHDRDRDVDKRDSSVSKDDKERESV--E 824
RTPP S +PPP K P S+S+ R S++ +SV +
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQ 868
Query: 825 KRHSSHPSPAPVLPVNALG-HTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAAD 883
+R SP P L H+ S + R +T R+ S SR ++
Sbjct: 869 RRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ-----------SPSRS--SSP 915
Query: 884 EHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKG 943
+ K K P + H G ++ PSP T R S S +
Sbjct: 916 QPKVKAIISPRQ--RSHSGSSS----------PSPSRVTSRTTPRRSRSVSPCSNVESRL 963
Query: 944 EPAYENPKKSS-EVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLAS 997
P Y + SS + KVK E PP Q+H S P P + PGP S
Sbjct: 964 LPRYSHSGSSSPDTKVKPET------PPR--QSHSGSISPYPKVKAQTPPGPSLS 1010
Score = 33.1 bits (74), Expect = 1.7
Identities = 54/263 (20%), Positives = 86/263 (32%), Gaps = 24/263 (9%)
Query: 732 VGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSF-----PTPPPWL 786
V G+ G + T +S H SV PH PP+ P+ L
Sbjct: 2469 VAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGE----PPASTGAQQPSALAAL 2524
Query: 787 KPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTR 846
+P + RS+S+++ SS S S + SS PV P AL
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS----LPVQPEVALKRVP 2580
Query: 847 SSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAG 906
S T + + + P +R+R S S ++ + ++
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKR-RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2639
Query: 907 EEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDH 966
+ + PSP P A P S ++ P GE +P+K + ++
Sbjct: 2640 SSSSSSSSSPSPAKPGP---QALPKPASPKKPPP--GERRSRSPRKPI-----DSLRDSR 2689
Query: 967 DLPPEAPQTHRASEPPPPNSSSS 989
L + R S P P S
Sbjct: 2690 SLSYSPVERRRPSPQPSPRDQQS 2712
Score = 32.3 bits (72), Expect = 2.9
Identities = 29/111 (26%), Positives = 40/111 (36%), Gaps = 14/111 (12%)
Query: 896 DGHGHEGRAAGEEAKQLA-RVPSPY--------VRTPVVESARPNSTSSREAEPRKGEPA 946
DG + + EAKQ A P PY R+P + + R P
Sbjct: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
Query: 947 YENPKKSSEVKVK---EERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGP 994
E K S + K + E +K H P P++ R S+ S S P P
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSP--TPKSKRKSKDKKRKRSRSTTPAP 255
Score = 32.3 bits (72), Expect = 2.9
Identities = 54/254 (21%), Positives = 87/254 (34%), Gaps = 40/254 (15%)
Query: 753 HKDGPSVQNFSNPHEPWNRLHRTPPSFP----------TPPPWLKPGELERSASAAAHDR 802
H+ PSV + + + R S P +P P KP L+RS S + ++
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP--KPRGLQRSRSRSRREK 1781
Query: 803 DRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALG---HTRSSTEQIRAHLNTE 859
R +RD S S +S +R S + V G H+RS Q + ++
Sbjct: 1782 TRTTRRRDRSGSS-----QSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR 1836
Query: 860 AREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPY 919
R + R R SRK +++ P K A ++
Sbjct: 1837 RR-----RGRSRTPPTSRK-----RSRSRTSPAPWKRSRSRASPATHRRSRS-------- 1878
Query: 920 VRTPVVESARPNSTSSREAEPR-KGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRA 978
RTP++ R S +S + R + + + S R+ PP + R+
Sbjct: 1879 -RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRS 1937
Query: 979 SEPPPPNSSSSVHP 992
P S S P
Sbjct: 1938 RTPTTRRRSRSRTP 1951
Score = 31.2 bits (69), Expect = 6.4
Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 11 RKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLAS------------SSGSDKED 58
RK+ RS + + RR+ A +A R+R+ S A+ S S +
Sbjct: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
Query: 59 NGKPPSSAP-----SRPRPPRRKRRESTSAEED 86
G P S P RP P ++ +S ED
Sbjct: 305 EGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
Score = 31.2 bits (69), Expect = 6.4
Identities = 60/303 (19%), Positives = 97/303 (32%), Gaps = 42/303 (13%)
Query: 695 HPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHK 754
H + +P P P + P +H E + P T G A + S TP+ G
Sbjct: 433 HASSSPESPKPAPA----PGSHREISSSP---TSKNRSHGRAKRDKSH-SHTPSRRMGRS 484
Query: 755 DGPSV--QNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELER---SASAAAHDRDRDVDKR 809
P+ + S P R H S P W + +R S S R R +
Sbjct: 485 RSPATAKRGRSRSRTPTKRGHSRSRS----PQWRRSRSAQRWGRSRSPQRRGRSRSPQRP 540
Query: 810 DSSVSKDDKER---ESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKP 866
S S++ + R S + S SPA +R+ + R+ T AR + +
Sbjct: 541 GWSRSRNTQRRGRSRSARRGRSHSRSPA----TRGRSRSRTPARRGRSRSRTPARRRSRS 596
Query: 867 KERERDHSESRKDLAADEHKAK-----------------EGHLPEKDGHGHEGRAAGEEA 909
+ R S SR +++ P + R
Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRG 656
Query: 910 KQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKS-SEVKVKEERKEDHDL 968
+ +R P+ R+ AR + S R+G P++ S + R H
Sbjct: 657 RSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSR 716
Query: 969 PPE 971
P+
Sbjct: 717 TPQ 719
Score = 30.8 bits (68), Expect = 8.3
Identities = 49/235 (20%), Positives = 79/235 (33%), Gaps = 16/235 (6%)
Query: 774 RTPP---SFPTPPPWLKPGELER---SASAAAHDRDRDVDK--RDSSVSKDDKERESVEK 825
RTPP S + P + L R SAS++ R R + R SVS + +S
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS 1742
Query: 826 RHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEH 885
R S + G + S + + +R + R RD S S + +
Sbjct: 1743 RRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQ 1802
Query: 886 KAKEGH---LPEKDGHGHEGR--AAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEP 940
+++ + G G+ R A E ++ +R RTP R S +S
Sbjct: 1803 RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWK 1862
Query: 941 R---KGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHP 992
R + PA +S + R P ++ + S S P
Sbjct: 1863 RSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP 1917
Score = 30.8 bits (68), Expect = 8.3
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 10/87 (11%)
Query: 354 PQPQVQRPPRP---QSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSS 410
P V PP Q P+ L L P + S+ S S S+ +SSS S +S SSS SS
Sbjct: 2502 PHSDVGEPPASTGAQQPSALAA--LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSS 2559
Query: 411 TP---AKTQPAPPHIS--HHPSASPFP 432
+ + P P ++ PS +P P
Sbjct: 2560 SSDSEGSSLPVQPEVALKRVPSPTPAP 2586
Score = 30.8 bits (68), Expect = 8.3
Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 3/80 (3%)
Query: 11 RKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSA---P 67
RK+R S S S + ++ + + + S +SSS S KP A P
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Query: 68 SRPRPPRRKRRESTSAEEDI 87
+ P+ P R S S + I
Sbjct: 2663 ASPKKPPPGERRSRSPRKPI 2682
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 63.5 bits (153), Expect = 1e-09
Identities = 87/332 (26%), Positives = 117/332 (35%), Gaps = 57/332 (17%)
Query: 300 PQVAQP--IPQPQTEPQLRAPSPDPDLVQRTEAP---PQPPPLSTQPPQGPPEAQLQP-- 352
PQ +P PQP+ EP L A +P L + E P PQP L P P P
Sbjct: 763 PQAEEPHLSPQPE-EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE 821
Query: 353 ---APQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRS 409
+PQP+ + PQS L P ++H S + PLS +
Sbjct: 822 PCLSPQPE-ESHLSPQSEEPCLSPR--PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPE 878
Query: 410 STPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNM---FAPPTAL 466
P P P +S P LS P PL S P P + S P++ PP L
Sbjct: 879 ELPLFPPPGEPSLS--PLLGEPALSEPGEPPL-SPLPEELPLSPSGEPSLSPQLMPPDPL 935
Query: 467 PPP-PPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFH 525
PPP P+ + + A P G EL F A +D + L P L T
Sbjct: 936 PPPLSPIITAAAPPALSPLG-----------ELEYPFGAKGDSDPESPLAAP-ILETPIS 983
Query: 526 QHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPP-------MFDKYPTKVDPFYRHS 578
+ P +PP + P+P P + + P + P +HS
Sbjct: 984 PPPEAN------------CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHS 1031
Query: 579 LFHSYPPAVSGIPPMIP-----PTGPFGSLQG 605
L P PP +P P P G + G
Sbjct: 1032 LVPQNSPPSQCSPPALPLSVPSPLSPIGKVVG 1063
Score = 54.7 bits (130), Expect = 5e-07
Identities = 96/351 (27%), Positives = 124/351 (35%), Gaps = 45/351 (12%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEA-QLQPAPQP 356
P P+ + P P+ P P E+P PPP P PPEA +L P P+
Sbjct: 574 PPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP-EESPLSPPPEASRLSPPPED 632
Query: 357 QVQRPP---RPQSPTQLLHQNLP-PVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTP 412
PP P SP + + P PV + S PLS S + +SR S P
Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692
Query: 413 AKTQPAPPHISHHPSASPFP----LSLP-NHSPLHSF--TPTLQPPAHSHHPNMFAPPTA 465
+ P P P ASP P +SLP SPL P L P + H +
Sbjct: 693 PEDSPTSPPPEDSP-ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPH 751
Query: 466 LPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFH 525
L P P S Q A P S E+ L L+ Q+ G L P P E H
Sbjct: 752 LSPRPEEPHLSPQ-AEEPHLSPQPEEPCLCAVPEEPHLSPQA--EGPHLSPQP---EELH 805
Query: 526 -QHQHQHQHTHQHTHQHTFTPFP---HAIPPT---AIMPTP----APPMFDKYPTKVDPF 574
Q + H + +P P H P + + P P P +K P P
Sbjct: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP- 864
Query: 575 YRHSLFHSYPPAVSG-IP-----PMIPPTGPFGSLQGAFQPKLTDPFRPML 619
PP G P P+ PP G +P L++P P L
Sbjct: 865 -------EKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPL 908
Score = 53.1 bits (126), Expect = 2e-06
Identities = 54/200 (27%), Positives = 75/200 (37%), Gaps = 27/200 (13%)
Query: 295 LKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPP-----QGPPEAQ 349
L + P + P P + P +P+ P R PP+ P S P + E+
Sbjct: 434 LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESP 493
Query: 350 LQPAPQPQVQRPPRPQSPTQLLHQN-LPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSR 408
L P P+ PP SP L ++ L P + P + +L PLS +S S
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP 553
Query: 409 SSTPAKTQPAPP-----HISHHPSASPF-------PLSLPNHS----PLHSFTPTLQPPA 452
S P + P P +S P SP P+S P + P +P PP
Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613
Query: 453 HSHHPNMFAPPTA--LPPPP 470
S + PP A L PPP
Sbjct: 614 ES---PLSPPPEASRLSPPP 630
Score = 52.8 bits (125), Expect = 2e-06
Identities = 57/188 (30%), Positives = 72/188 (38%), Gaps = 25/188 (13%)
Query: 300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPP--LSTQPPQGPPEAQLQPAPQPQ 357
P+ + P P +T P P P E+P PPP L T PP P ++L P P+
Sbjct: 523 PEESPPSPALET-PLSPPPEASPLSPPFEESPLSPPPEELPTSPP--PEASRLSPPPEES 579
Query: 358 VQRPP---RPQSPTQLLHQNLPPVQAHP-SAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA 413
PP P SP + PP + P S PLS +S S S P
Sbjct: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP 639
Query: 414 KTQP--APPHISHHPSASPFPL-----SLPNHSPLH---SFTPTLQPPAHSHHPNMFAPP 463
+ P PP +S SP P+ P SPL +PT PP S + PP
Sbjct: 640 EESPMSPPPEVSR---LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS---RLSPPP 693
Query: 464 TALPPPPP 471
P PP
Sbjct: 694 EDSPTSPP 701
Score = 51.6 bits (122), Expect = 5e-06
Identities = 49/174 (28%), Positives = 66/174 (37%), Gaps = 19/174 (10%)
Query: 300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQ 359
PQ+ P+ + P L P P E+P PPP +++ PP +L +P P+
Sbjct: 428 PQLEAPLNEEM--PLLPPPEESPLSPPPEESPTSPPPEASR--LSPPPEELPASPLPEAL 483
Query: 360 RPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAP 419
RP + P+ P LS P + S L + LS S P+ P
Sbjct: 484 HLSRPLEES--------PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETP 535
Query: 420 PHISHHPSASPF--PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
+S P ASP P SP PT PP S + PP P PP
Sbjct: 536 --LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS---RLSPPPEESPMSPP 584
Score = 51.6 bits (122), Expect = 5e-06
Identities = 190/870 (21%), Positives = 270/870 (31%), Gaps = 190/870 (21%)
Query: 278 QEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPP--QPP 335
Q K D ++ + L+ P A P P P + SP T A +PP
Sbjct: 2087 QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPP 2146
Query: 336 PLSTQPPQGPPEAQLQPAPQPQVQRP---PRPQSPTQLLHQNLPPVQAHPSAQSLSQPLS 392
S P P E L+ PQ Q P P +P L P A P+ P
Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFP--TAPPTYPPYPSPTG 2204
Query: 393 AYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFT------- 445
A + L + S + P + PP H ++P P P L +
Sbjct: 2205 APAQPPM-LGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263
Query: 446 -------PTLQPPAHSH--------HPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSE 490
P L PP + A + PP S H G
Sbjct: 2264 GGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKT 2323
Query: 491 QDILRQELNTRFLASQSADRGASLG-----PPPYLRTEFHQHQHQHQHTHQHTHQHTFTP 545
D+ + L R ASQ + LG PPP Q +H F P
Sbjct: 2324 PDVFKAPLTPR--ASQVEPQSPGLGLRPQEPPP----------AQALAPSPPSHPDIFRP 2371
Query: 546 ----FPHAIPPTAIMPTPAPP----MFDKYPTKVDPFYR-----HSLFHSYPPAV----- 587
P+A PP P P PP DPF R S S P
Sbjct: 2372 GSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLS 2431
Query: 588 ------SGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQ 641
S + P P+ + +P+ DPF P+ + P A + H
Sbjct: 2432 AEAFCPSPVTPRFQSPDPYS--RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSL 2489
Query: 642 KVKKQMQSDP--------HKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGA 693
+ P K+ G P F+ R PG F P P +
Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFV-RSPGTGAFVGTPSPMRFTFPQAV-GEPSL 2547
Query: 694 AHPTGTPFGPPPHHSNFLNPAAHLEP---FNRPSTFTGLAAVGGNAFGGLGNPSVTPNSM 750
P P PPPH N +H P +P + A G F G+P
Sbjct: 2548 KPPVPQPGLPPPHGIN-----SHFGPGPTLGKPQSTNYTVATGN--FHPSGSP------- 2593
Query: 751 FGHKDGPSVQNFS-NPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKR 809
G G + +++ +P P + L PP+ P+L G +RS + V+KR
Sbjct: 2594 LGPSSGSTGESYGLSPLRPPSVL--PPPAPDGSLPYLSHGASQRSGITS------PVEKR 2645
Query: 810 DSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKER 869
+ + + E + P ++ L T ++ R L RE ++
Sbjct: 2646 EDPGTGMGSSLATAELPGTQDPG------MSGLSQTELEKQRQRQRL----RELLIRQQI 2695
Query: 870 ERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESAR 929
+R+ K+ AA A G + G E + E QL+R +P+ T
Sbjct: 2696 QRNTLRQEKETAA----AAAGAVGPPGSWGAEPSSPAFE--QLSRGQTPFAGT------- 2742
Query: 930 PNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEA-PQTHRASEPPPPNSSS 988
KSS V + + L P + P R S PPPP + S
Sbjct: 2743 --------------------QDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPS 2782
Query: 989 SV-------------------HPGPL----------------ASMPMTVGVTGIHPMNSI 1013
S+ +PG L A+ M ++ P
Sbjct: 2783 SMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPG 2842
Query: 1014 SSLDRTRMMTPFMGISP-LPG-GERFPYPS 1041
L R + +P GIS LPG GE P P+
Sbjct: 2843 PELGRQALGSPLAGISTRLPGPGEPVPGPA 2872
Score = 50.1 bits (118), Expect = 1e-05
Identities = 92/369 (24%), Positives = 122/369 (33%), Gaps = 68/369 (18%)
Query: 298 PCPQVAQPIP----QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQP---PQGPPE--- 347
P P+ ++ P P + P +P P R PP+ P+S P P PP
Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS 651
Query: 348 --------AQLQPAPQPQVQRPPRPQSPT----QLLHQNLPPVQAHPSAQSLSQPLSAYN 395
++L P P+ PP +SPT + + PP + S P S
Sbjct: 652 RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP 711
Query: 396 SSSL-SLNSLSSSRSSTPAKTQPAP----PHIS---HHPSASPFPLSLPNHSPLHSFTPT 447
SL SL S P + Q P PH+S P SP P P+ SP + P
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP-EEPHLSP-QAEEPH 769
Query: 448 LQP----------PAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQE 497
L P P H P P P L P S E+ L +
Sbjct: 770 LSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLS--PQTEEPHLSPVPEEPCLSPQ 827
Query: 498 LNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMP 557
L+ QS + L P P + H + +P P PP
Sbjct: 828 PEESHLSPQSEE--PCLSPRP-----------EESHLSPELEKPPLSPRPEK-PPEEPGQ 873
Query: 558 TPAPPMFDKYPTKVDPFYRHSLFHSYPPAVS--GIPPMIP-----PTGPFGSLQGAFQPK 610
PAP +P +P L PA+S G PP+ P P P G + Q
Sbjct: 874 CPAPEELPLFPPPGEPSLSPLLGE---PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
Query: 611 LTDPFRPML 619
DP P L
Sbjct: 931 PPDPLPPPL 939
Score = 49.3 bits (116), Expect = 2e-05
Identities = 102/425 (24%), Positives = 131/425 (30%), Gaps = 77/425 (18%)
Query: 310 QTEPQLRAPSPD--PDLVQRTEAPPQPPPLS--TQPPQ-----GPPEAQLQPAPQPQVQR 360
Q EPQL AP + P L E+P PPP T PP PP +L +P P+
Sbjct: 425 QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALH 484
Query: 361 -----------PPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRS 409
PP +SP PP ++ P + PLS S S +
Sbjct: 485 LSRPLEESPLSPPPEESPLS------PPPESSPFSPLEESPLSPPEESPPS--PALETPL 536
Query: 410 STPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALP-P 468
S P + P P P SP P LP P + L PP M PP P
Sbjct: 537 SPPPEASPLSPPFEESP-LSPPPEELPTSPPPEA--SRLSPP--PEESPMSPPPEESPMS 591
Query: 469 PPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQ 528
PPP S S E+ L L+ D + + PPP
Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPED--SPMSPPP---------- 639
Query: 529 HQHQHTHQHTHQHTFTPFP---HAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPP 585
+ +P P PP P PP ++ PT P + S PP
Sbjct: 640 -EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP--EESPTSPPP---EASRLSPPP 693
Query: 586 --AVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKV 643
+ + PP P P P P P+ +P + C
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP-QLC----------------- 735
Query: 644 KKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGP 703
PH +P RP P L PH +P A P +P
Sbjct: 736 --PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAE 793
Query: 704 PPHHS 708
PH S
Sbjct: 794 GPHLS 798
Score = 49.3 bits (116), Expect = 2e-05
Identities = 58/221 (26%), Positives = 81/221 (36%), Gaps = 27/221 (12%)
Query: 266 PIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLV 325
P P L S+ + P E + P P+ + P +P P P L
Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP-PSPAL- 532
Query: 326 QRTEAPPQPPPLST-------QPPQGPPEAQLQPAPQPQVQR--PPRPQSPTQLLHQNLP 376
E P PPP ++ + P PP +L +P P+ R PP +SP +
Sbjct: 533 ---ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE-S 588
Query: 377 PVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPP----HISHHPSASPF- 431
P+ P A L P + S LS S S P ++ +PP +S P SP
Sbjct: 589 PMSPPPEASRLFPP---FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS 645
Query: 432 -PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P + SPL + PP S + PP P PP
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEES---PLSPPPEESPTSPP 683
Score = 48.1 bits (113), Expect = 5e-05
Identities = 60/236 (25%), Positives = 78/236 (33%), Gaps = 24/236 (10%)
Query: 257 PEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEP--VVLKDPCPQVAQPIPQPQTEPQ 314
PE P ++S S + P+ P V P P V++ P P+ P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
Query: 315 LRAP-----SPDPDLVQRTEAP---PQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQS 366
P SP P+ + + P P PP P PPE L P + P P+
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEE 731
Query: 367 PTQLLHQNLPPVQAHPSAQSLS-QPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHIS-- 423
P P + P LS +P + S LS P PH+S
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ 791
Query: 424 -HHPSASPFPLSL--------PNHSPLHSFTPTLQP-PAHSHHPNMFAPPTALPPP 469
P SP P L P+ SP+ P L P P SH P P P
Sbjct: 792 AEGPHLSPQPEELHLSPQTEEPHLSPVPE-EPCLSPQPEESHLSPQSEEPCLSPRP 846
Score = 43.5 bits (101), Expect = 0.001
Identities = 48/187 (25%), Positives = 73/187 (39%), Gaps = 40/187 (21%)
Query: 318 PSPDPD-LVQRTEAPPQPPPLSTQPPQ--GPPEAQLQPAPQPQVQRPPRPQSPTQLLHQN 374
P+ +PD L + P+ +++ P+ GP + + +P + VQ P+ ++P L++
Sbjct: 381 PTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP---LNEE 437
Query: 375 LP-----------------PVQAHPSAQSLSQPLSAYNSSSL-SLNSLSSSRSSTPAKTQ 416
+P P P A LS P +S L LS +P
Sbjct: 438 MPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPP 497
Query: 417 PAPPHISHHPSASPF------PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPP 470
P +S P +SPF PLS P SP +P L+ P + PP A P P
Sbjct: 498 PEESPLSPPPESSPFSPLEESPLSPPEESPP---SPALETP-------LSPPPEASPLSP 547
Query: 471 PLTSGSL 477
P L
Sbjct: 548 PFEESPL 554
Score = 43.5 bits (101), Expect = 0.001
Identities = 86/444 (19%), Positives = 148/444 (33%), Gaps = 72/444 (16%)
Query: 98 TFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRN 157
+ + L++ L+ Q++++++Q +++++ L ++ +L ++ +
Sbjct: 3896 SLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQL 3955
Query: 158 LCQHLGKRKKMPKALRQLKPGQ-NSCRDSDSESASGESK-GFHRSSSRERLSDSSAPSSL 215
Q ++++ + +Q + G N R S + + + L S+P +L
Sbjct: 3956 QQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGAL 4015
Query: 216 GTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLE 275
G ++ A S + ++ L +GT PE + + G + P +SG
Sbjct: 4016 GPTLLLTGK--EQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSG-- 4071
Query: 276 RSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQP---QTEPQLRAPSPDPDLV------- 325
SQ +P QP PQP Q +P LR P V
Sbjct: 4072 ----DSQLLLVQP---------------QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG 4112
Query: 326 ----------QRTEAPPQP-----PPLSTQPPQGPPEAQLQPAPQPQVQRP------PRP 364
+EA P P +S G L QP ++RP P+P
Sbjct: 4113 GGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQP 4172
Query: 365 QSPTQLLH--QNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRS------------S 410
P +L Q LP V P+ L L + + L LS +
Sbjct: 4173 PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQ 4232
Query: 411 TPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAH--SHHPNMFAPPTALPP 468
+ PP+ SP L L F P P PP P
Sbjct: 4233 QSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAP 4292
Query: 469 PPPLTSGSLQVAGHPAGSTYSEQD 492
P L++G + HP S Q+
Sbjct: 4293 PGALSTGPVLGPVHPTPPPSSPQE 4316
Score = 43.1 bits (100), Expect = 0.002
Identities = 54/191 (28%), Positives = 73/191 (38%), Gaps = 30/191 (15%)
Query: 299 CPQVAQ-PIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQ 357
CP + P+ P EP L +P L + P PPLS P + P +P+ PQ
Sbjct: 874 CPAPEELPLFPPPGEPSLSPLLGEPALSE-----PGEPPLSPLPEELPLSPSGEPSLSPQ 928
Query: 358 VQRP-PRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSS----LSLNSLSSSRSSTP 412
+ P P P + ++ PP A L P A S L+ L + S P
Sbjct: 929 LMPPDPLPPPLSPIITAAAPP--ALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPP 986
Query: 413 ----AKTQPAPPHISHHPSASPF----PLSL----PNHSPL--HSFTPTLQPPAHSHHPN 458
+P PP I SP P+ + P SPL HS P PP+ P
Sbjct: 987 EANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP- 1045
Query: 459 MFAPPTALPPP 469
A P ++P P
Sbjct: 1046 --ALPLSVPSP 1054
Score = 42.4 bits (98), Expect = 0.003
Identities = 55/191 (28%), Positives = 69/191 (36%), Gaps = 41/191 (21%)
Query: 287 EPIFEPVVLK-DPCPQVAQPIPQPQTEPQLRAPSPDPDLVQ----RTEAPPQPP---PLS 338
EP P ++ DP P PI P L SP +L + ++ P+ P P+
Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITAAAPPAL---SPLGELEYPFGAKGDSDPESPLAAPIL 978
Query: 339 TQPPQGPPEAQL-QPAPQPQVQRPPRPQSPT---------------------QLLHQNLP 376
P PPEA P P P + PP P SP L+ QN P
Sbjct: 979 ETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSP 1038
Query: 377 PVQAHPSAQSLS--QPLSAYN-----SSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSAS 429
P Q P A LS PLS S L+ + + + S P P S PS
Sbjct: 1039 PSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPM 1098
Query: 430 PFPLSLPNHSP 440
LS P SP
Sbjct: 1099 G-DLSCPAPSP 1108
Score = 40.8 bits (94), Expect = 0.008
Identities = 100/409 (24%), Positives = 133/409 (32%), Gaps = 95/409 (23%)
Query: 227 QEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCK 286
+ KA + E+L + P G L DS +G + GLE K+ D K
Sbjct: 2280 ESRKALEVKKEELGAS-----SPSYGPPNLGFVDSPSSGT---HLGGLEL---KTPDVFK 2328
Query: 287 EPI------FEP----VVLKDPCPQVAQPI-PQPQTEPQLRAPSPDPDLVQRTEAPPQPP 335
P+ EP + L+ P AQ + P P + P + P D P P
Sbjct: 2329 APLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD-------PYAQP 2381
Query: 336 PLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYN 395
PL+ P+PQ PP P+S L ++LP S P S
Sbjct: 2382 PLT---------------PRPQ---PPPPESCCALPPRSLP-----------SDPFSRVP 2412
Query: 396 SSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSH 455
+S S +S S + P + P SP P S P P + P A H
Sbjct: 2413 ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP-----QSRDPFAPLH 2467
Query: 456 HPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQ------SAD 509
P PP L SL G PA EL+ + + Q S
Sbjct: 2468 KPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG----ELHAKVPSGQPPNFVRSPG 2523
Query: 510 RGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIM------PTPAPPM 563
GA +G P +R F Q + P P PP I PT P
Sbjct: 2524 TGAFVGTPSPMRFTFPQAVGEPSLKPP-------VPQPGLPPPHGINSHFGPGPTLGKPQ 2576
Query: 564 FDKYPTKVDPFY---------RHSLFHSYPPAVSGIPPMIPPTGPFGSL 603
Y F+ S SY + P ++PP P GSL
Sbjct: 2577 STNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSL 2625
Score = 39.7 bits (91), Expect = 0.018
Identities = 54/197 (27%), Positives = 68/197 (34%), Gaps = 43/197 (21%)
Query: 293 VVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQ- 351
V+ K+P + P Q Q + L R P Q P T P QG Q Q
Sbjct: 4204 VLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQL 4263
Query: 352 ---PAPQ----PQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSL 404
P PQ ++ PRPQ P P + A P A S L +
Sbjct: 4264 GGFPGPQTGPLQELGAGPRPQGP--------PRLPAPPGALSTGPVLGPVH--------- 4306
Query: 405 SSSRSSTPAKTQPAPPHISHHPSASPFPLS-LPNHSPLHSFTPTLQPPAHSHHPNMFAPP 463
TP + P P PS P P S LP + L PP H P P
Sbjct: 4307 -----PTPPPSSPQEP---KRPSQLPSPSSQLPTEAQL--------PPTHPGTPKP-QGP 4349
Query: 464 TALPPPPPLTSGSLQVA 480
T PPP ++ + Q+A
Sbjct: 4350 TLEPPPGRVSPAAAQLA 4366
Score = 36.6 bits (83), Expect = 0.15
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 6/74 (8%)
Query: 295 LKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPP-----PLSTQPPQGPPEAQ 349
L P P+ P P P P +P +P + TE +PP PL++ P P+ +
Sbjct: 4906 LSAPPPEEPSPPPSPLA-PSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
Query: 350 LQPAPQPQVQRPPR 363
+P + + RPPR
Sbjct: 4965 ARPPEEGEDSRPPR 4978
Score = 36.2 bits (82), Expect = 0.20
Identities = 38/127 (29%), Positives = 49/127 (38%), Gaps = 14/127 (11%)
Query: 274 LERSQEKSQDCCKEPIF-EPVVLKDP------CPQVAQPIPQPQTEP-QLRAPSPDPDLV 325
++R ++SQ + P + EP P C P PQT P Q P P
Sbjct: 4227 MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP 4286
Query: 326 QRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLL--HQNLPPVQAHPS 383
R APP LST P GP P+ + +RP + SP+ L LPP HP
Sbjct: 4287 PRLPAPPGA--LSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPP--THPG 4342
Query: 384 AQSLSQP 390
P
Sbjct: 4343 TPKPQGP 4349
Score = 34.7 bits (78), Expect = 0.58
Identities = 53/205 (25%), Positives = 70/205 (34%), Gaps = 34/205 (16%)
Query: 314 QLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQS-PTQLLH 372
+L P P + +PPP +T QL Q QR P P S P Q
Sbjct: 2755 KLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQ 2814
Query: 373 QNLPPVQAHPSAQSLSQPLSAYNSSS----LSLNSLS------SSRSSTPAKTQPAPP-- 420
Q L Q +A S+ +SA S+ L +L S+R P + P P
Sbjct: 2815 QQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGP 2874
Query: 421 ----HISHH------PSASPFPLSLPNHSPLHSFTPTLQPPAHSHHP--------NMFAP 462
+ H+ P +PFP P P F P + P H P + P
Sbjct: 2875 AQFIELRHNVQKGLGPGGTPFPGQGPPQRP--RFYPVSEDP-HRLAPEGLRGLAVSGLPP 2931
Query: 463 PTALPPPPPLTSGSLQVAGHPAGST 487
PP P + SL H G T
Sbjct: 2932 QKPSAPPAPELNNSLHPTPHTKGPT 2956
Score = 34.7 bits (78), Expect = 0.58
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 12/93 (12%)
Query: 379 QAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPS-ASPFPLSLPN 437
Q P+ + +Q YN S+L + LS+ P +P+PP PS +P P S P
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSA-----PPPEEPSPP-----PSPLAPSPASPPT 4930
Query: 438 HSPLHSFT-PTLQPPAHSHHPNMFAPPTALPPP 469
+ T P +PP S P +P +A P P
Sbjct: 4931 EPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
Score = 33.5 bits (75), Expect = 1.3
Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 8/86 (9%)
Query: 305 PIPQPQTEPQLRAPSPDPDLVQRTEAPPQ---PPPLSTQP-PQGPPEAQLQPAPQPQVQR 360
P P+P T+ + D+ Q + PP+ PPP P P PP L P +
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 361 PPRPQSPTQLLHQNLPPVQAHPSAQS 386
PP P SP L P A P ++
Sbjct: 4944 PPVP-SPLPLASS---PESARPKPRA 4965
Score = 33.1 bits (74), Expect = 1.7
Identities = 35/140 (25%), Positives = 48/140 (34%), Gaps = 8/140 (5%)
Query: 922 TPVVESARPNSTSS--REAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRAS 979
TP P S R EP + +P ++ + + PP P+
Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRP---- 2387
Query: 980 EPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPY 1039
+PPPP S ++ P L S P + V S S T P P RF
Sbjct: 2388 QPPPPESCCALPPRSLPSDPFS-RVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS 2446
Query: 1040 PS-FHWDPIRDPLRDPYREL 1058
P + P R RDP+ L
Sbjct: 2447 PDPYSRPPSRPQSRDPFAPL 2466
Score = 32.3 bits (72), Expect = 2.9
Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 10/94 (10%)
Query: 317 APSPDPDLVQRTEAPPQP-PPLSTQPPQGPPEAQ-----LQPAPQPQVQRPPRPQSPTQL 370
+PS P L+ T+ P Q P QPPQGPP Q L P +P P T L
Sbjct: 3620 SPSQSPRLL--TKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTAL 3677
Query: 371 LHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSL 404
Q Q A SL+ P + +L+L SL
Sbjct: 3678 AQQQ--QQQHSGGAGSLAGPSGGFFPGNLALRSL 3709
Score = 31.2 bits (69), Expect = 6.4
Identities = 48/192 (25%), Positives = 65/192 (33%), Gaps = 29/192 (15%)
Query: 375 LPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLS 434
L P + P A S+P A + R +P + A P + P+A+ L
Sbjct: 3094 LGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLG 3153
Query: 435 L-----------------PNHSPLH-----SFTPTLQPPAHSHHPNMFAPP--TALPPPP 470
L P S H SF T PPAH P+ + P ++L
Sbjct: 3154 LKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKF 3213
Query: 471 PLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSAD----RGASLGPPPYLRTEFHQ 526
L SG+L + G PA S E D + L L D L L +
Sbjct: 3214 ELESGALTLPGGPAASG-DELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQP 3272
Query: 527 HQHQHQHTHQHT 538
Q Q Q QH+
Sbjct: 3273 AQQQQQQQQQHS 3284
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 63.5 bits (153), Expect = 1e-09
Identities = 51/166 (30%), Positives = 66/166 (39%), Gaps = 26/166 (15%)
Query: 310 QTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQ 369
Q+ P+ P P P Q+ P QPPP P Q PP P P Q Q PP PQ ++
Sbjct: 53 QSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPP----HPQPHQQQQPPPPPQDSSK 108
Query: 370 LLHQN----LPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHH 425
+ P V + P A S + P + S + S P T PP ++
Sbjct: 109 PVVAQGPGPAPGVGSAPPASSSAPPATPPTS--------GAPPGSGPGPTPTPPPAVTSA 160
Query: 426 PSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P +P P +P S PT P A P PP A+P P P
Sbjct: 161 PPGAPPP------TPPSSGVPTTPPQAGGPPP----PPAAVPGPGP 196
Score = 54.7 bits (130), Expect = 5e-07
Identities = 58/164 (35%), Positives = 64/164 (39%), Gaps = 34/164 (20%)
Query: 314 QLRAP-SPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLH 372
Q R P P P Q PP PPP Q Q PP Q P P Q PP PQ P Q
Sbjct: 42 QNRGPMGPGPG--QSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQ-PHQ--- 95
Query: 373 QNLPPVQAHPSAQSLSQPLSAYNSSSL-SLNSLSSSRSSTPAKTQPAPPHISHHPSASPF 431
Q PP P Q S+P+ A + S + SS P T PP P + P
Sbjct: 96 QQQPP----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPAT---PPTSGAPPGSGPG 148
Query: 432 PLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSG 475
P TPT P S APP A PPP P +SG
Sbjct: 149 P------------TPTPPPAVTS------APPGA-PPPTPPSSG 173
Score = 36.6 bits (83), Expect = 0.15
Identities = 49/207 (23%), Positives = 55/207 (26%), Gaps = 62/207 (29%)
Query: 417 PAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGS 476
P P P P P P P QPP H P+ PPPPP S
Sbjct: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108
Query: 477 LQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQ 536
VA P + G PP
Sbjct: 109 PVVAQGPGPAP-----------------------GVGSAPP------------------- 126
Query: 537 HTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPP 596
+ P A PPT + APP PT PPAV+ PP PP
Sbjct: 127 -----ASSSAPPATPPT----SGAPPGSGPGPTPTP-----------PPAVTSAPPGAPP 166
Query: 597 TGPFGSLQGAFQPKLTDPFRPMLRKPG 623
P S P+ P P PG
Sbjct: 167 PTPPSSGVPTTPPQAGGPPPPPAAVPG 193
Score = 35.0 bits (79), Expect = 0.44
Identities = 34/112 (30%), Positives = 38/112 (33%), Gaps = 14/112 (12%)
Query: 249 PELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQ 308
P GVG+ P S A P P SG P P V P P P P
Sbjct: 117 PAPGVGSAPPASSS-APPATPPTSGAPPGSGPGPT----PTPPPAVTSAP-PGAPPPTPP 170
Query: 309 ----PQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQP 356
P T PQ P P P V P P P P GP ++ P+P
Sbjct: 171 SSGVPTTPPQAGGPPPPPAAV----PGPGPGPKQGPGPGGPKGGKMPGGPKP 218
Score = 30.8 bits (68), Expect = 8.3
Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 1/60 (1%)
Query: 930 PNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSS 989
P S P P ++ ++ + ++ H PP PQ H+ +PPPP SS
Sbjct: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPH-PQPHQQQQPPPPPQDSS 107
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 63.5 bits (153), Expect = 1e-09
Identities = 59/194 (30%), Positives = 83/194 (42%), Gaps = 32/194 (16%)
Query: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQ---------LQ 351
+VAQP P E + P + + + EAP P L+T P G PE+ +
Sbjct: 409 EVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPS-LATSPALGHPESTPKSLHPWYGIT 467
Query: 352 PAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSST 411
P P+ ++ P P++P+ P+ H S S S+P SA S +LS+ SLSS +S
Sbjct: 468 PTSSPKTKKRPAPRAPSA------SPLALHASRLSHSEPPSATPSPALSVESLSSESASQ 521
Query: 412 PAKTQ----PAPPHIS-----HHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAP 462
A + PA P S H P P+SL +S L S ++P
Sbjct: 522 TAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQ-------M 574
Query: 463 PTALPPPPPLTSGS 476
P A P P T GS
Sbjct: 575 PQASPGLAPRTRGS 588
Score = 44.3 bits (103), Expect = 7e-04
Identities = 61/223 (27%), Positives = 85/223 (38%), Gaps = 52/223 (23%)
Query: 305 PIPQPQTEPQ----LRAPSPDPDLVQRTEAPPQ--PPPLSTQPPQGPPEAQLQPA----- 353
P+P+P+ P+ AP DP + +A P+ P PL GPP +
Sbjct: 348 PVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGT 407
Query: 354 -----PQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSL--SQPLSAYNSSSLSLNSLS- 405
P P +P +P + + + P+A SL S L S+ SL+
Sbjct: 408 EEVAQPSPTASLESKPYNPFE--EEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYG 465
Query: 406 -SSRSSTPAKTQPAPPHISHHPSASPFPL--SLPNHSPLHSFTPT--------------- 447
+ SS K +PAP PSASP L S +HS S TP+
Sbjct: 466 ITPTSSPKTKKRPAP----RAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQ 521
Query: 448 ------LQPPA---HSHHPNMFAPPTALPPPPPLTSGSLQVAG 481
L+PPA S P + AP T P T+ SL +G
Sbjct: 522 TAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSG 564
Score = 40.8 bits (94), Expect = 0.008
Identities = 52/238 (21%), Positives = 76/238 (31%), Gaps = 12/238 (5%)
Query: 768 PWNRLHRTPPSF-PTP-PPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEK 825
PW L + P P P PP PG + + + +V + + S + K E+
Sbjct: 370 PWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEE 429
Query: 826 RHSSHPSPAPVLPV----NALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLA 881
AP P ALGH S+ + + K K+R + S LA
Sbjct: 430 EEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLA 489
Query: 882 ADEHKAKEGHLPEKDGHG--HEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAE 939
+ P + E A Q A + + P V +
Sbjct: 490 LHASRLSHSEPPSATPSPALSVESLSSESASQTA--GAELLEPPAVPKSSSEPAVHAPGT 547
Query: 940 PRKGEPAYENPKKSSEVKVKEERKED--HDLPPEAPQTHRASEPPPPNSSSSVHPGPL 995
P N +S ++ E R E P AP+T +S P P S P PL
Sbjct: 548 PGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPL 605
Score = 37.4 bits (85), Expect = 0.089
Identities = 62/261 (23%), Positives = 91/261 (34%), Gaps = 46/261 (17%)
Query: 303 AQPIPQPQTEPQLRAPSPDPDLV----------------QRTEAPPQPPPLSTQPPQGPP 346
A P +PQ + R P +L T APP P P S+ +
Sbjct: 272 ASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLV 331
Query: 347 E---------AQLQPAPQPQVQRPPRPQSPTQLLHQNLP---PVQAHPSAQSLSQPLSAY 394
E +L P P+ + P+P T ++ P VQA P + P S+
Sbjct: 332 EQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSS- 390
Query: 395 NSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTL-QPPAH 453
+ S +S T QP+P +PF + P+L PA
Sbjct: 391 SPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPAL 450
Query: 454 SH--------HPNMFAPPTALPP----PPPLTSGSLQVAGHPAGSTYSEQDILRQE--LN 499
H HP PT+ P P P + +A H + ++SE L+
Sbjct: 451 GHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALS 510
Query: 500 TRFLASQSADR--GASLGPPP 518
L+S+SA + GA L PP
Sbjct: 511 VESLSSESASQTAGAELLEPP 531
Score = 34.3 bits (77), Expect = 0.75
Identities = 65/304 (21%), Positives = 102/304 (33%), Gaps = 42/304 (13%)
Query: 305 PIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRP 364
P QP+ + Q + D+ + P P+ PEA +PQ+ P +P
Sbjct: 233 PFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEA------RPQI--PTKP 284
Query: 365 QSPTQLLHQNLPPV-----------QAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA 413
+ P +L PP ++ A +P S+ +L + SSS +
Sbjct: 285 RVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRL 344
Query: 414 KTQPAP-PHISHHPS-ASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P P P + PS +P P P L P +P PP++ P PP
Sbjct: 345 HELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAP--------LPPSSSPGPPS 396
Query: 472 LTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQH 531
S ++ G + S L + F + D+ P L T H
Sbjct: 397 QDSRQVENGGTEEVAQPSPTASLESKPYNPF-EEEEEDKEEEAPAAPSLAT---SPALGH 452
Query: 532 QHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHS--LFHSYPPAVSG 589
+ + + P + P T P P P P H+ L HS PP+ +
Sbjct: 453 PESTPKSLHPWYGITPTSSPKTKKRPAPRAP-------SASPLALHASRLSHSEPPSATP 505
Query: 590 IPPM 593
P +
Sbjct: 506 SPAL 509
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 63.2 bits (152), Expect = 2e-09
Identities = 74/258 (28%), Positives = 96/258 (37%), Gaps = 45/258 (17%)
Query: 260 DSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCP-----QVAQPIPQPQTEP- 313
+S G VP +G+ D +PV P P Q+A QPQ
Sbjct: 550 ESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAG 609
Query: 314 --QL------RAPSPDPDLVQRTEAPPQP-PPLSTQPPQGPPEAQLQPA----PQPQVQR 360
QL A P P ++R P P PP PP G P Q P +
Sbjct: 610 SHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPK 669
Query: 361 PPR--PQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPA 418
PP P PTQ H PP Q PSA S LSA S SL+ + + P A
Sbjct: 670 PPTRSPSPPTQ--HTGQPPGQ--PSAPS---QLSAPRRYSSSLSPIQAPNHPPPQPPTQA 722
Query: 419 PP--HISHHPSASPFPLSLPN--------HSPLHSFTPTLQPPAHSHHPNMFAPPTALPP 468
P H + P P++LP+ H+P + TP PP +P +LP
Sbjct: 723 TPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNP-------SLPA 775
Query: 469 PPPLTSGSLQVAGHPAGS 486
P L G+ + A AG+
Sbjct: 776 PQTLAGGNPETAQPHAGT 793
Score = 50.8 bits (120), Expect = 8e-06
Identities = 54/206 (26%), Positives = 68/206 (33%), Gaps = 45/206 (21%)
Query: 313 PQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQG------PPEAQ-LQPAPQPQVQRPPRPQ 365
P + P P D A P+PPP S++ P A L+ P P PP+P+
Sbjct: 521 PAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPK 580
Query: 366 SPTQLL-------------HQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTP 412
P QN P A S+ QP +A S +L + P
Sbjct: 581 DPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAP 640
Query: 413 AKT-QPAPPH---------ISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAP 462
K P P H H PS SP P P SP T QPP P+ +
Sbjct: 641 PKPGNPPPGHPGGQSSSGTSQHPPSLSPKP---PTRSPSPPTQHTGQPPGQPSAPSQLSA 697
Query: 463 PTAL------------PPPPPLTSGS 476
P PPP P T +
Sbjct: 698 PRRYSSSLSPIQAPNHPPPQPPTQAT 723
Score = 44.3 bits (103), Expect = 7e-04
Identities = 47/158 (29%), Positives = 62/158 (39%), Gaps = 23/158 (14%)
Query: 298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQ 357
P QP QP QL AP + +AP P PPQ P +A +P
Sbjct: 678 PTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHP------PPQPPTQATPLMHTKPN 731
Query: 358 VQRPPRPQS-PTQL-LHQ--NLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPA 413
Q PP P + P++ L Q + PP P + + PL N S + +L+ T
Sbjct: 732 SQGPPNPMALPSEHGLEQPSHTPPQTPTPPS---TPPLGKQNPSLPAPQTLAGGNPET-- 786
Query: 414 KTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPP 451
A PH P P P+ P + P S P QPP
Sbjct: 787 ----AQPHAGTLP--RPRPVPKPRNRP--SVPPPPQPP 816
Score = 34.3 bits (77), Expect = 0.75
Identities = 43/164 (26%), Positives = 59/164 (35%), Gaps = 14/164 (8%)
Query: 445 TPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLA 504
+P QPP + P A P PPP +S + +G G+ S IL Q + +
Sbjct: 520 SPAFQPPLPPTDGSTVVP--AGPEPPPQSSRAESSSG--GGTVPSSAGILEQGPSPGDGS 575
Query: 505 SQSADRGASLGPPPYLRTEFH----QHQHQ-----HQHTHQHTHQHTFTPFPHAIPPTAI 555
S P R Q+Q Q HQ + H + P PH +
Sbjct: 576 PPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPH-NAAGPSPHTLRRAVK 634
Query: 556 MPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGP 599
P PAPP P S +PP++S PP P+ P
Sbjct: 635 KPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPP 678
Score = 30.8 bits (68), Expect = 8.3
Identities = 38/129 (29%), Positives = 47/129 (36%), Gaps = 29/129 (22%)
Query: 666 PPGPSLFGAIHHPHDLA-RPSTLFSAAGAAH---PTGTPFGP-----PPHHSNFLNP--A 714
P G S G HP L+ +P T + H P G P P P +S+ L+P A
Sbjct: 651 PGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQA 710
Query: 715 AHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHR 774
+ P P+ T L N+ G PN M PS P
Sbjct: 711 PNHPPPQPPTQATPLMHTKPNSQG-------PPNPM----ALPSEHGLEQP-------SH 752
Query: 775 TPPSFPTPP 783
TPP PTPP
Sbjct: 753 TPPQTPTPP 761
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 63.2 bits (152), Expect = 2e-09
Identities = 99/415 (23%), Positives = 141/415 (33%), Gaps = 64/415 (15%)
Query: 2 DGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGK 61
DGP R G + R S GA G GR R + G+ E
Sbjct: 1165 DGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLE---- 1220
Query: 62 PPSSAPSRPRPPRRKRRESTSAEEDI--IDGFAMTSFVTFEALEKDVALKPQERVEKRQT 119
P + P+ TS+ + I D ++ S +T E +E + + VE++Q
Sbjct: 1221 PLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKI-----KEVEEKQP 1275
Query: 120 PLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKAL--RQLKP 177
+ K + + L F KS HP Y + L L K +P ++ R L+P
Sbjct: 1276 EM---KSGFMASFLDF--LKSGKRHPPLYQA------GLTPPLSPPKSVPPSVPARGLQP 1324
Query: 178 GQNSCR-------------DSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSD 224
+ E+A E G S +RL + + F +
Sbjct: 1325 QPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDE 1384
Query: 225 SDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIV---------PKISGLE 275
D K D E + + + DP L P+ S GP + P + GL
Sbjct: 1385 EDSVAKNRDLQ-ESISSAISALDDPPLAG---PKDTSTPDGPPLAPAAAVPGPPPLPGLP 1440
Query: 276 RSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPP 335
+ EP +L++ P P P PQ +P P P P L P PP
Sbjct: 1441 SANSNGTP-------EPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPAL-------PSPP 1486
Query: 336 PLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
PL P PP L P P P + PP P P P A PS + P
Sbjct: 1487 PLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELP 1541
Score = 49.3 bits (116), Expect = 2e-05
Identities = 46/170 (27%), Positives = 60/170 (35%), Gaps = 32/170 (18%)
Query: 325 VQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSA 384
+ + PP P T P GPP A P P PP+ PSA
Sbjct: 1402 ISALDDPPLAGPKDTSTPDGPPLAPAAAVPGP-------------------PPLPGLPSA 1442
Query: 385 QSLSQPLSAYNSSSLSLNSLSSSRSSTPAKT-QPAPPHISHHPSASPFPLSLPNHSPLHS 443
S P L + PA T QP PP P P +LP+ PL +
Sbjct: 1443 NSNGTP-------EPPLLEEKPPPTPPPAPTPQPQPP-----PPPPPPQPALPSPPPLVA 1490
Query: 444 FTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDI 493
TP+ PP P A P+ PPPPP + PA + + ++
Sbjct: 1491 PTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540
Score = 45.4 bits (106), Expect = 3e-04
Identities = 176/779 (22%), Positives = 245/779 (31%), Gaps = 148/779 (18%)
Query: 284 CCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPP------PL 337
C P P+ D CP P P P P+ R P + + PP+P PL
Sbjct: 1128 CRSRPALSPLGDIDFCP----PNPGPDG-PRRRGRKPTK---AKRDGPPRPRGRPRIRPL 1179
Query: 338 STQPPQGPPEAQLQP--APQPQVQ-----RPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
GP A A +P+ + R T+L + L P++ S +
Sbjct: 1180 EVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRL--EPLKPLKIKLSVPKAGEG 1237
Query: 391 LSAYNSSSLS---LNSLSSS--RSSTPAK---TQPAPPHISHHPSAS--PFPLSLPNHSP 440
L + ++S NSL SS R AK + P + AS F S H P
Sbjct: 1238 LGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPP 1297
Query: 441 LHS--FTPTLQPP--------AHSHHPNMFAPPTALPPPPPLTS----GSLQVA------ 480
L+ TP L PP A P A P A+P PPP + G+L+ A
Sbjct: 1298 LYQAGLTPPLSPPKSVPPSVPARGLQPQPPATP-AVPHPPPSGAFGLGGALEAAESEGLG 1356
Query: 481 -GHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTH 539
G P+ ++++ R N L S S+D S+ L+
Sbjct: 1357 LGCPSPCKRLDEELKR---NLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGP 1413
Query: 540 QHTFTPFPHAIPPTAIMPTPAP-PMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTG 598
+ T TP + P A +P P P P + P PP + PP PP
Sbjct: 1414 KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTP---------EPPLLEEKPPPTPPPA 1464
Query: 599 PFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGL 658
P Q P P +P L P A S P
Sbjct: 1465 PTPQPQ---PPPPPPPPQPALPSPPPLVA------------------PTPSSP------- 1496
Query: 659 KPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNP-AAHL 717
P L PP P++ P A P A P P P P + HL
Sbjct: 1497 PPPPLPPPPPPAMPSPPPPPPPAAAP--------LAAPPEEPAAPSPEDPELPDTRPLHL 1548
Query: 718 EPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPS----VQNFSNPHEPWNRLH 773
+ G GG G + +D PS +Q P W
Sbjct: 1549 AKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQK 1608
Query: 774 RTPPSFPTPPPWLKPGELERSASA--------AAHDRDRDVDKRDSSVSKDDKERESVEK 825
F P +K G+ + A++ A + R K +V+K D R K
Sbjct: 1609 ALLQKF---TPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARK 1665
Query: 826 RHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEH 885
P P +PV G ++ + PK + + S K
Sbjct: 1666 -----PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEK----PPE 1716
Query: 886 KAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARP----NSTSSREAEPR 941
+ E +PE A E+ L V + V RP +TS R+ P
Sbjct: 1717 QTPETAMPEP--------PAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPE 1768
Query: 942 K----GEPAYENPKKSSEVKVKEE---RKEDHDLPPEAPQTHRASEPPPPNSSSSVHPG 993
+ G+PA K+ KVK E +K L PP +S S PG
Sbjct: 1769 RSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPG 1827
Score = 40.0 bits (92), Expect = 0.014
Identities = 39/146 (26%), Positives = 51/146 (34%), Gaps = 23/146 (15%)
Query: 332 PQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPL 391
P PPP + Q Q P L A P + P P Q LP V +H + S S
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPP-----QLLPSVLSHAPSPSPS--- 815
Query: 392 SAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPP 451
+S + ++ L + + P PP P P PL L H H P P
Sbjct: 816 ----ASKVGVHLLEPATRDGAPQPPPPPP-----PPPPPMPLQLEAHLRSHGLEPAAPSP 866
Query: 452 AHSHHPNMFAPPT------ALPPPPP 471
++ P AL P PP
Sbjct: 867 RLRPEESLDPPGAMQELLGALEPLPP 892
Score = 37.4 bits (85), Expect = 0.089
Identities = 55/232 (23%), Positives = 87/232 (37%), Gaps = 35/232 (15%)
Query: 163 GKRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCD 222
G +++ AL L P S + G +RS S + + AP + C
Sbjct: 878 GAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQ---GTKAPRFVPLTSICF 934
Query: 223 SDS--DQEEKASDASSEKLFNTVIVNK-----------DPELGVGTLPEHDSQDA-GPIV 268
DS EE++ + E++F + DP+ G G P + D GP
Sbjct: 935 PDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYC 994
Query: 269 P-KISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQR 327
P + SG + ++ +P P + P A+P+ Q+ P AP P P
Sbjct: 995 PGRASG---AGPETPGLGLDPNKPPEL---PSTVNAEPLGLIQSGPHQAAPPPPP----- 1043
Query: 328 TEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQ 379
PP PPP P+G + + + +P + S LL + PP Q
Sbjct: 1044 ---PPPPPPAPASEPKGGLTSPIFCSTKP---KKLLKTSSFHLLRRRDPPFQ 1089
Score = 35.4 bits (80), Expect = 0.34
Identities = 45/163 (27%), Positives = 56/163 (34%), Gaps = 34/163 (20%)
Query: 331 PPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
P Q PP PP PP PPR PTQ NL S S
Sbjct: 221 PAQTPPYRPGPPDPPP--------------PPR-HLPTQF---NL--------LASSSAA 254
Query: 391 LSAYNSSSLSLNSLSSSRSSTPAKTQPAP------PHISHHPSASPFPLSLPNHSPLHSF 444
+A SS L + S + P + P H SA P P P H+ H
Sbjct: 255 AAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYL 314
Query: 445 TPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGST 487
+ P+ H N+ P P P +G AG P+G+T
Sbjct: 315 SCGGSYPSMGHRANLACSPLGGGEPSP-GAGEPSKAG-PSGAT 355
Score = 35.4 bits (80), Expect = 0.34
Identities = 53/211 (25%), Positives = 75/211 (35%), Gaps = 47/211 (22%)
Query: 292 PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQ--RTEAPPQPPPLSTQPPQGPPEAQ 349
P+VL P PQ+ + P A L++ + PQPPP PP PP
Sbjct: 791 PLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPP---PPPPPPPPMP 847
Query: 350 LQ--------------PAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYN 395
LQ P+P+ + + P Q L L P+ P + P
Sbjct: 848 LQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPP----- 902
Query: 396 SSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQ------ 449
+S + + RS +P T+ AP + ++ FP SL SF PT++
Sbjct: 903 -NSEGKDPAGAYRSPSPQGTK-APRFVP--LTSICFPDSLLQDEE-RSFFPTMEEMFGGG 957
Query: 450 ---------PPAHSHHPNMFAPPTALPPPPP 471
PP P A P PP PP
Sbjct: 958 AADDYGKAGPPEDEGDPKAGAGP---PPGPP 985
Score = 33.9 bits (76), Expect = 0.99
Identities = 48/198 (24%), Positives = 72/198 (36%), Gaps = 48/198 (24%)
Query: 667 PGPSLFGAIHHPHDL-ARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPST 725
P S A HP +RP + S+ P PF PP + + HL+P P+
Sbjct: 143 PSSSALSAYQHPASFGSRPFPVPSSLSLQDP---PFSPPANGLLSPHDVLHLKPSQAPTV 199
Query: 726 FTGLA---AVGGNAFGGLG-NPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPT 781
+ L GG G G P+ TP P+ P P P
Sbjct: 200 PSSLGFERLAGGGVLGPAGLGPAQTP-----------------PYRP-------GPPDPP 235
Query: 782 PPPWLKPGE--LERSASAAAHDRDRDVDK-------------RDSSVSKDDKERESVEKR 826
PPP P + L S+SAAA ++ + + ++ + D + ++
Sbjct: 236 PPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRP 295
Query: 827 HSSHPSPAPVLPVNALGH 844
S+ P P P P +AL H
Sbjct: 296 ASAQPPPPPP-PAHALQH 312
Score = 33.5 bits (75), Expect = 1.3
Identities = 42/143 (29%), Positives = 50/143 (34%), Gaps = 31/143 (21%)
Query: 332 PQPPPLSTQ-PPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQP 390
P P LS Q PP PP L SP +LH L P QA P+ S
Sbjct: 163 PVPSSLSLQDPPFSPPANGLL--------------SPHDVLH--LKPSQA-PTVPS---- 201
Query: 391 LSAYNSSSLSLNSLSSSRSSTPAKTQPA--PPHISHHPSASPFPLSLPNHSPLHSFTPTL 448
SL L+ PA PA PP+ P P P LP L + +
Sbjct: 202 -------SLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAA 254
Query: 449 QPPAHSHHPNMFAPPTALPPPPP 471
A P ++ A P PPP
Sbjct: 255 AAAAEQSSPQLYNFSGAAPGPPP 277
Score = 32.7 bits (73), Expect = 2.2
Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 5/82 (6%)
Query: 1156 PHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPP----LISTLGGRPVSPR 1211
P P P LPS P ++PT + PP A+ +PPP + L P P
Sbjct: 1473 PPPPPPQPALPSPP-PLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPA 1531
Query: 1212 RTTPLSAEIRERPPSHTLKDIE 1233
+P E+ + P H K E
Sbjct: 1532 APSPEDPELPDTRPLHLAKKQE 1553
Score = 31.2 bits (69), Expect = 6.4
Identities = 23/71 (32%), Positives = 28/71 (39%), Gaps = 13/71 (18%)
Query: 412 PAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
P Q P +SH PS SP + H L+P P PP PPPPP
Sbjct: 796 PPPPQLLPSVLSHAPSPSPSASKVGVH--------LLEPATRDGAPQ--PPPPPPPPPPP 845
Query: 472 LTSGSLQVAGH 482
+ LQ+ H
Sbjct: 846 M---PLQLEAH 853
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 62.0 bits (149), Expect = 3e-09
Identities = 102/409 (24%), Positives = 137/409 (33%), Gaps = 95/409 (23%)
Query: 270 KISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVA-------QPIPQPQTEPQLRAPSPD- 321
++ L++ +K C +P P P P + QP P P P A S
Sbjct: 60 QLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQK 119
Query: 322 ----------------PDLV-QRTEAPPQPPPLSTQPPQG--PPEAQLQPAPQPQVQRPP 362
P LV E+PP+ PP+ PP PP P PQP PP
Sbjct: 120 QQQYKHQMLHHQRDGPPGLVPMELESPPESPPV---PPGSYMPPSQSYMPPPQP----PP 172
Query: 363 RPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHI 422
PT LPP Q PS S P +Y + + S +S SSS S ++
Sbjct: 173 SYYPPTS-SQPYLPPAQPSPSQ---SPPSQSYLAPTPSYSSSSSSSQS----------YL 218
Query: 423 SHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGH 482
SH S P + P+ P+ H + L PPPP +
Sbjct: 219 SHSQSYLPSSQASPSR------------PSQGHSKSQL-----LAPPPP--------SAP 253
Query: 483 PAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHT 542
P T +Q+ L + Q A+ P P T Q Q+ ++ Q T
Sbjct: 254 PGNKTTVQQEPLESGAKNKSTEQQQ----AAPEPDPSTMTPQEQQQYWYRQHLLSLQQRT 309
Query: 543 FTPFP-HAIPPTAIMPTPAPPMFDKY--PTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGP 599
P H P TP P + T P S PP +PP +PP
Sbjct: 310 KVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPE-- 367
Query: 600 FGSLQGAFQPKLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQ 648
+P+ DP K + A H WQ H Q +V Q Q
Sbjct: 368 --------EPQSEDPEEDARLKQLQAAAAH----WQ-QHQQHRVGFQYQ 403
Score = 49.3 bits (116), Expect = 2e-05
Identities = 59/197 (29%), Positives = 66/197 (33%), Gaps = 26/197 (13%)
Query: 292 PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPL-------STQPPQG 344
P V P +P P P L P P L P PPP+ S PP
Sbjct: 519 PFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGM 578
Query: 345 PPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSL 404
PP L A P V PP L PPV PS S + P + L L
Sbjct: 579 PP--SLSSAGPPPVLPPP------SLSSAGPPPVLPPPSLSSTAPP------PVMPLPPL 624
Query: 405 SSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMF--AP 462
SS+ P I +A+P P P S S P PA P F AP
Sbjct: 625 SSATPPPGIPPPGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAP 681
Query: 463 PTALPPPPPLTSGSLQV 479
PT PP S QV
Sbjct: 682 PTTYHPPLQSAGPSEQV 698
Score = 48.9 bits (115), Expect = 3e-05
Identities = 68/269 (25%), Positives = 98/269 (36%), Gaps = 38/269 (14%)
Query: 203 RERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELG-VGTLPEHDS 261
RERLSD PS + S + +S SSE + + ++ D LG V L +
Sbjct: 1398 RERLSDRWYPSDVDR----HSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQH 1453
Query: 262 QDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKD--PCPQVAQPIPQPQTEPQLRAPS 319
+ ++ L +E+ Q +KD PQ+A +P ++ Q +
Sbjct: 1454 EIILKAAQELKMLREQKEQLQK-----------MKDFGSEPQMADHLPPQESRLQNTSSR 1502
Query: 320 PDPDLVQRTEAPPQP---PPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLP 376
P + PP P PP S P PP P +P V PP P P P
Sbjct: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPP----LPPP 1558
Query: 377 PVQAHPSAQSLSQPL----SAY----NSSSLSLNSLSSSRSST--PAKTQPAPPHISHHP 426
P P ++ Q S Y + LNS S ++ A P PP S P
Sbjct: 1559 PPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIP 1618
Query: 427 SASPFPLSLPNHSPLHSFTPTLQPPAHSH 455
P P+ +P P+ P Q + H
Sbjct: 1619 PPGPVPMGMP---PMSKPPPVQQTVDYGH 1644
Score = 47.0 bits (110), Expect = 1e-04
Identities = 148/675 (21%), Positives = 211/675 (31%), Gaps = 104/675 (15%)
Query: 409 SSTPAKTQPAPPHISHHPSASPFP-------LSLPNHSPLHSFTPT----LQPPAHSHHP 457
S P P PP ++ P ASP P + P+ S SF LQ H
Sbjct: 12 SHYPPPPVPPPPPVAL-PEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQK 70
Query: 458 NM-------FAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADR 510
M PP LPPPP + G P
Sbjct: 71 QMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPP-------------------------- 104
Query: 511 GASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTK 570
+ PPP + Q Q Q+ HQ H P P +P P +PP
Sbjct: 105 -PPMPPPPGPALSY---QKQQQYKHQMLHHQRDGP-PGLVPMELESPPESPP-------- 151
Query: 571 VDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKLTDPFRPMLRKPGKWCAMHV 630
V P SY P P PPT L A P P +
Sbjct: 152 VPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSS 211
Query: 631 HIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSA 690
+ H Q Q+ P + G L PP PS A + L S
Sbjct: 212 SSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPS---APPGNKTTVQQEPLESG 268
Query: 691 AGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSM 750
A P P S + P + + R + + G P V ++
Sbjct: 269 AKNKSTEQQQAAPEPDPST-MTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTP 327
Query: 751 FGHKDGPSVQNFSN-PHEPWNRLHRTPPSFPTPPPWLKPGE-----------LERSASAA 798
K+ +V S P P + PP PP L P E L++ +AA
Sbjct: 328 EPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAA 387
Query: 799 AH---DRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNA----LGHTRSSTEQ 851
AH + V + + + + + + +++ P P + + L H +Q
Sbjct: 388 AHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQ 447
Query: 852 IRAHLNTEAREKDKPKERERDHSESRKDLAAD---EHKAKEGHLPEKDGHGHEGRAAGEE 908
+ HL E E++ E+ HS KD + + K +GH+ + E + +
Sbjct: 448 FQ-HLYQEW-EREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQN 505
Query: 909 AKQL----ARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKE 964
K +P P+V P + P T P P P + V
Sbjct: 506 MKNQYMGNMSMPPPFV--PYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMP-- 561
Query: 965 DHDLPPEAPQTHRASEPPP--PNSSSSVHPGPLASMP--MTVGVTGIHPMNSISSLDRTR 1020
PP P + S PPP P S SS P P+ P + G + P S+SS
Sbjct: 562 ----PPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPP 617
Query: 1021 MM--TPFMGISPLPG 1033
+M P +P PG
Sbjct: 618 VMPLPPLSSATPPPG 632
Score = 47.0 bits (110), Expect = 1e-04
Identities = 57/208 (27%), Positives = 75/208 (36%), Gaps = 36/208 (17%)
Query: 300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPL-------STQPPQGPPEAQLQP 352
P + +P P P L + P P L + + PPP+ ST PP P L
Sbjct: 567 PSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSS 626
Query: 353 A-PQPQVQRPPRPQS-PTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSS 410
A P P + P PQ P QL +PP + S+Q +P A + +S S
Sbjct: 627 ATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGS------- 679
Query: 411 TPAKTQPAPPHISHHPSASPFPLSLPNHS--------PLHSFTPTLQPPAHSHHPNMFAP 462
APP H P S P N P SF+ S P+ P
Sbjct: 680 -------APPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQ--P 730
Query: 463 PTALPPPPPLTSGSLQVAGHPAGSTYSE 490
TA+ P + G L P S+Y E
Sbjct: 731 ITAVKDMPVRSGGLLP---DPPRSSYLE 755
Score = 45.4 bits (106), Expect = 3e-04
Identities = 57/194 (29%), Positives = 68/194 (35%), Gaps = 28/194 (14%)
Query: 288 PIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQ--PPPLST--QPPQ 343
P P VL P P P T P P P T PP PP LS+ PP
Sbjct: 531 PTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPV 590
Query: 344 GPPEAQLQPAPQPQVQRP------PRPQSPTQLLHQNLPPVQAHPSA--QSLSQPLSAYN 395
PP + P P + P P P P L PP P Q + L+A
Sbjct: 591 LPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAP 650
Query: 396 SSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSH 455
S SS S P K +PA P P+S +P ++ P LQ S
Sbjct: 651 VPPAS----SSQSSQVPEKPRPA---------LLPTPVSF-GSAPPTTYHPPLQSAGPSE 696
Query: 456 HPNMFAP--PTALP 467
N AP +ALP
Sbjct: 697 QVNSKAPLSKSALP 710
Score = 45.1 bits (105), Expect = 4e-04
Identities = 69/284 (24%), Positives = 99/284 (34%), Gaps = 55/284 (19%)
Query: 292 PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQG------- 344
P VL P A P P P L + +P P + P PP S PP G
Sbjct: 588 PPVLPPPSLSSAGP-PPVLPPPSLSSTAPPPVM-------PLPPLSSATPPPGIPPPGVP 639
Query: 345 ---PPEAQLQPAP------QPQVQRPPRPQ-SPTQLLHQNLPPVQAHPSAQSLSQPLSAY 394
PP+ P P QV PRP PT + + PP HP QS + P
Sbjct: 640 QGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQS-AGPSEQV 698
Query: 395 NSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHS 454
NS + S+S+ P + + + +A P++ P+ S PP S
Sbjct: 699 NSKA------PLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSS 752
Query: 455 HHPNMFAPPTALP--------------PPPPLTSGSL------QVAGHPAGSTYSEQDIL 494
+ + P P P P G+ + GHPA T S+ ++
Sbjct: 753 YLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMI 812
Query: 495 RQELNTRFLASQSADRGASLGPPPYL--RTEFHQHQHQHQHTHQ 536
+ ++F + S P + + F Q QHQ Q Q
Sbjct: 813 PRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQ-QHQQQPKSQ 855
Score = 44.3 bits (103), Expect = 7e-04
Identities = 59/216 (27%), Positives = 78/216 (36%), Gaps = 27/216 (12%)
Query: 309 PQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPP---RPQ 365
P P + P P P T PP PP S PP PP PA P PP P
Sbjct: 518 PPFVPYSQMPPPLP-----TMPPPVLPP-SLPPPVMPPAL---PATVPPPGMPPPVMPPS 568
Query: 366 SPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHH 425
PT + +PP + + P S ++ + S S+ P P PP S
Sbjct: 569 LPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSAT 628
Query: 426 PSASPFPLSLPNHSPLHSFTPTLQPPAHSH---------HPNMFAPPTALPPPPPLT-SG 475
P P +P P T PPA S P + P + PP T
Sbjct: 629 PPPGIPPPGVPQGIP-PQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHP 687
Query: 476 SLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRG 511
LQ AG P+ S+ + + L +S S+D+G
Sbjct: 688 PLQSAG-PSEQVNSKAPLSKSALP---YSSFSSDQG 719
Score = 42.7 bits (99), Expect = 0.002
Identities = 82/366 (22%), Positives = 124/366 (33%), Gaps = 94/366 (25%)
Query: 260 DSQDAGPIVPKISGLERSQEKSQDCCKE---------PIFEPVVLKDPCPQVAQPIP--- 307
D Q P +P G S +K Q + P P+ L+ P P+ + P+P
Sbjct: 99 DWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESP-PE-SPPVPPGS 156
Query: 308 -QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQS 366
P ++ + P P P T + P PP P Q PP +Q AP P S
Sbjct: 157 YMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPP-SQSYLAPTPSYSSSSS-SS 214
Query: 367 PTQLLHQN--LP--------PVQAHPSAQSLSQPLSAY---NSSSLSLNSLSSSRSSTPA 413
+ L H LP P Q H +Q L+ P + N +++ L S +
Sbjct: 215 QSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKST 274
Query: 414 KTQPAPP------------------------------HISHHPSA------SPFPL---- 433
+ Q A P H+ H +P P+
Sbjct: 275 EQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEV 334
Query: 434 SLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSG--------SLQVAG---- 481
++P S + + +PP PN PP LPP P + LQ A
Sbjct: 335 TVPATSQVPESPSSEEPPLPP--PNEEVPPP-LPPEEPQSEDPEEDARLKQLQAAAAHWQ 391
Query: 482 ----HPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQH 537
H G Y Q I+++ + + Q + PPP+++T Q +H Q
Sbjct: 392 QHQQHRVGFQY--QGIMQKHTQLQQILQQYQQ---IIQPPPHIQTMSVDMQLRHYEMQQQ 446
Query: 538 THQHTF 543
QH +
Sbjct: 447 QFQHLY 452
Score = 38.9 bits (89), Expect = 0.031
Identities = 51/198 (25%), Positives = 71/198 (35%), Gaps = 31/198 (15%)
Query: 174 QLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSA-PSSLGTGYFCDSDSDQEEKAS 232
Q P Q+ + S S+S S + S S+ L S A PS G+ S + A
Sbjct: 193 QSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGH-----SKSQLLAP 247
Query: 233 DASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFE- 291
S N V ++P + Q A P P S + QE+ Q ++ +
Sbjct: 248 PPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAP-EPDPSTMT-PQEQQQYWYRQHLLSL 305
Query: 292 --------------PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPL 337
PVV KD V + + P T +PS +E PP PPP
Sbjct: 306 QQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPS--------SEEPPLPPPN 357
Query: 338 STQPPQGPPEAQLQPAPQ 355
PP PPE P+
Sbjct: 358 EEVPPPLPPEEPQSEDPE 375
Score = 38.5 bits (88), Expect = 0.040
Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 43/173 (24%)
Query: 409 SSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPP 468
S P PP PSA P S+P P P PP PP LPP
Sbjct: 1511 SYRPPPPMGKPPGSIVRPSAPPARSSVPVTRP-----PVPIPPP--------PPPPPLPP 1557
Query: 469 PPPL---TSGSLQVAGHPAGSTYSEQDIL-RQELNTRFLASQSADRGASLGPPPYLRTEF 524
PPP+ + +++ S Y D Q LN+ F + +A A + PPP
Sbjct: 1558 PPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPP------ 1611
Query: 525 HQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRH 577
P +IPP +P PPM P + Y H
Sbjct: 1612 --------------------PVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGH 1644
Score = 35.0 bits (79), Expect = 0.44
Identities = 53/224 (23%), Positives = 69/224 (30%), Gaps = 65/224 (29%)
Query: 401 LNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMF 460
+NS + ++ PP + + P P P P P + P + P
Sbjct: 500 VNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPG 559
Query: 461 APPTALPP------PPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASL 514
PP +PP PPP SL AG P L S +S
Sbjct: 560 MPPPVMPPSLPTSVPPPGMPPSLSSAGPPP-----------------VLPPPSL---SSA 599
Query: 515 GPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPT-PAPPMFDKYPTKVDP 573
GPPP L P ++ TA P P PP+ P P
Sbjct: 600 GPPPVLP-------------------------PPSLSSTAPPPVMPLPPLSSATPPPGIP 634
Query: 574 FYRHSLFHSYPPAV-SGIPPMI--PPTGPFGSLQGAFQPKLTDP 614
PP V GIPP + P P S Q + P+ P
Sbjct: 635 ----------PPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRP 668
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 60.8 bits (146), Expect = 8e-09
Identities = 62/212 (29%), Positives = 74/212 (34%), Gaps = 40/212 (18%)
Query: 288 PIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEA-----PPQPPPLSTQPP 342
P+ P V PC P P P T P L S D + + PP PPPL PP
Sbjct: 213 PVVAPPV---PCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPP 269
Query: 343 QGPPEAQLQPA-PQPQVQRPPRPQSPTQLLHQNLPP-VQAHPSAQSLSQPLSAYNSSSLS 400
G P + +PA P Q PP P P LPP P A + PL NSS
Sbjct: 270 CGYPGLKAEPASPAQDAQEPPAPPPP-------LPPYASCSPRASLPAPPLPGVNSS--- 319
Query: 401 LNSLSSSRSSTPAKTQPAPPHISHHP-----SASPFPLSLPNHSPLHSFTPTLQPPAHSH 455
S TP P P P A P P + P P LQ H
Sbjct: 320 --------SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPF------LQKKRHG- 364
Query: 456 HPNMFAPPTALPPPPPLTSGSLQVAGHPAGST 487
P PP PP S + +++ +T
Sbjct: 365 RPGAGGGKLNPPPAPPARSPTTELSSKSQQAT 396
Score = 58.2 bits (139), Expect = 5e-08
Identities = 70/263 (26%), Positives = 91/263 (34%), Gaps = 34/263 (12%)
Query: 264 AGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSP--- 320
+GP++P S + ++ + P V P P P P P P L + SP
Sbjct: 141 SGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPP--TPPPPPPPLPPPLPSSSPIKT 198
Query: 321 ----DPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLP 376
P + + P PP+ PP PP P P P QL +LP
Sbjct: 199 PLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLP 258
Query: 377 PVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLP 436
P+ P L P Y S + PA P PP+ S P AS LP
Sbjct: 259 PI---PPPLPLLPP-CGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLP 314
Query: 437 NHSPLHSFTPTLQPPAHSHH-PNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILR 495
+ P L P + S P A ALP PP P GS Q L+
Sbjct: 315 GVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPA-----------PPGS----QPFLQ 359
Query: 496 QELNTRFLASQSADRGASLGPPP 518
++ + R A G L PPP
Sbjct: 360 KKRHGRPGAG-----GGKLNPPP 377
Score = 52.4 bits (124), Expect = 3e-06
Identities = 95/402 (23%), Positives = 132/402 (32%), Gaps = 61/402 (15%)
Query: 249 PELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQ 308
P LG P A P+ S L R+ K + I + L+ + PQ
Sbjct: 16 PPLGA---PPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQ 72
Query: 309 PQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQV---------- 358
++ + + + T PP L G P L+PA Q V
Sbjct: 73 IESS---KGTNKEGGGSANTRGASTPPTLGDLFAGGFPV--LRPAGQRDVAGGKTGQGPG 127
Query: 359 QRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPA 418
R P P+ P + + L P P++ L A+ ++ R++ P PA
Sbjct: 128 SRAPSPRLPNKTISGPLIP----PASPRLGNTSEAHGAA----------RTAPPRPNVPA 173
Query: 419 PPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNM--FAPPTALPPPPPLTSGS 476
PP + P P P LP+ SP+ TP + PP N+ APP PPPP
Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIK--TPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP 231
Query: 477 LQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPP-PYLRTEFHQHQHQHQHTH 535
P S S++ + Q + PP P L + +
Sbjct: 232 PTPPPLPPASVLSDKAVKPQLAPLHL---------PPIPPPLPLLPPCGYPGLKAEPASP 282
Query: 536 QHTHQHTFTPFPHAIP-----PTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGI 590
Q P P P P A +P P P + P S PP +G
Sbjct: 283 AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGA 342
Query: 591 PPMIPPTGPFGS---LQ-------GAFQPKLTDPFRPMLRKP 622
+ P P GS LQ GA KL P P R P
Sbjct: 343 QALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
Score = 39.7 bits (91), Expect = 0.018
Identities = 47/190 (24%), Positives = 67/190 (35%), Gaps = 37/190 (19%)
Query: 305 PIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQ-GPPEAQLQPAPQPQVQRPPR 363
P P P P L AP P PP PP+ST + + + A +Q+ R
Sbjct: 8 PPPLPPPPPPLGAPPP---------PPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58
Query: 364 PQSPTQLLHQNLPPVQ------------AHPSAQSLSQPLSAYNSSSLSLNSLSSSRSST 411
+ TQ+ ++ P ++ A+ S L + + + R
Sbjct: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVA 118
Query: 412 PAKTQPAP------PHISHHPSASPF--PLS--LPNHSPLHSFTPTLQPPAHSHHPNMFA 461
KT P P + + + P P S L N S H T P PN+ A
Sbjct: 119 GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP-----RPNVPA 173
Query: 462 PPTALPPPPP 471
PP PPPPP
Sbjct: 174 PPPPTPPPPP 183
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 59.7 bits (143), Expect = 2e-08
Identities = 87/349 (24%), Positives = 134/349 (38%), Gaps = 35/349 (10%)
Query: 28 GGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDI 87
GG A G+G AL L S KE + +S RPRP ST AEED
Sbjct: 870 GGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRP-------STPAEEDE 922
Query: 88 IDGFAMTSFVTFEALEKDVA------LKPQERVEKR-QTPLTKKKREALTNGLSFHSKKS 140
D EK+ KP +R E+R +T +K AL + S++S
Sbjct: 923 DD----------PEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQES 972
Query: 141 RLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSE-SASGESKGFHR 199
+ E D + + + KK ++ G++ DS S+ S +S G +
Sbjct: 973 SSEKDEEDDEEDEEDEDREEAVDTTKKET----EVSDGEDEESDSSSKCSLYADSDGEND 1028
Query: 200 SSS-RERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPE 258
S+S E S SS+ SS + S S E +S+ E+ + + P +P
Sbjct: 1029 STSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPT 1088
Query: 259 HDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAP 318
+ P+ +++G + Q+ P P + P P P P AP
Sbjct: 1089 PAPVEV-PVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEP-PAGPP---AP 1143
Query: 319 SPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSP 367
+P PD + P PPP + ++ PAP+P PP+ + P
Sbjct: 1144 APRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFP 1192
Score = 39.7 bits (91), Expect = 0.018
Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 3/89 (3%)
Query: 383 SAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLH 442
+ Q+ + P S+ + +S + S P Q PP P P+ SLP P H
Sbjct: 569 NGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPH 628
Query: 443 SFTPTLQPPAHSHHPNMFAPPTALPPPPP 471
L P P + PP PPPPP
Sbjct: 629 QPAYLLPPRPDGPPPPEYPPP---PPPPP 654
Score = 38.1 bits (87), Expect = 0.052
Identities = 50/228 (21%), Positives = 80/228 (35%), Gaps = 22/228 (9%)
Query: 784 PWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALG 843
P K E S + A + R + +DD E+E E P P G
Sbjct: 891 PSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEK-EAGEPGRPGTKPPKRDEERG 949
Query: 844 HTR----------SSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLP 893
T+ S E+ ++E E+D ++ E + E D E + +G
Sbjct: 950 KTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDE 1009
Query: 894 EKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKS 953
E D A + + + S ES+ +S+SS + + + + S
Sbjct: 1010 ESDSSSKCSLYADSDGENDSTSDS--------ESSSSSSSSSSSSSSSSSSSSSSSSESS 1061
Query: 954 SEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMT 1001
SE + +EER LP +P P P V P +A P+T
Sbjct: 1062 SEDEEEEERPA--ALPSASPPPREVPVPTPAPVEVPV-PERVAGSPVT 1106
Score = 37.7 bits (86), Expect = 0.068
Identities = 27/77 (35%), Positives = 28/77 (36%), Gaps = 15/77 (19%)
Query: 305 PIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRP 364
P P P T PQ P P P PP PPP P G P QP PPRP
Sbjct: 594 PPPAP-TPPQQPPPPPPP--------PPPPPPYLASLPLG------YPPHQPAYLLPPRP 638
Query: 365 QSPTQLLHQNLPPVQAH 381
P + PP H
Sbjct: 639 DGPPPPEYPPPPPPPPH 655
Score = 37.4 bits (85), Expect = 0.089
Identities = 70/300 (23%), Positives = 94/300 (31%), Gaps = 64/300 (21%)
Query: 300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQ 359
P+ ++P Q P AP P+ PP+P P +++ +P+P
Sbjct: 415 PEPSRPTDQDYRPPASEAPPPE---------PPEPGGGGGGGGPSPEREEVRTSPRP--A 463
Query: 360 RPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAP 419
P R SP P H S S + L S S + S T + + +
Sbjct: 464 SPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLA-----SDTEEEEENSS 518
Query: 420 PHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQV 479
+ + S P S H P TP PPA ++ ++ PT P T S +
Sbjct: 519 MVLGARDTGSEVP-SGSGHGPC---TP---PPAPANFEDV--APTG-SGEPGATRESPKA 568
Query: 480 AGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTH 539
G S S D + DRG S P P
Sbjct: 569 NGQNQASPCSSGDDME---------ISDDDRGGSPPPAP--------------------- 598
Query: 540 QHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGP 599
TP P PP P P PP P P H + PP G PP P P
Sbjct: 599 ----TP-PQQPPPPPPPPPPPPPYLASLPLGYPP---HQPAYLLPPRPDGPPPPEYPPPP 650
Score = 36.2 bits (82), Expect = 0.20
Identities = 40/150 (26%), Positives = 57/150 (38%), Gaps = 15/150 (10%)
Query: 384 AQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHS 443
++S S S+ +SSS S +S SSS S + ++ + + PSASP P +P +P
Sbjct: 1033 SESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPV 1092
Query: 444 FTPTLQ---------------PPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTY 488
P + PA P +PP+A PP +G A P
Sbjct: 1093 EVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPS 1152
Query: 489 SEQDILRQELNTRFLASQSADRGASLGPPP 518
S +L R S SA PP
Sbjct: 1153 SPIPLLPPPKKRRKTVSFSAIEVVPAPEPP 1182
Score = 32.0 bits (71), Expect = 3.7
Identities = 42/198 (21%), Positives = 70/198 (35%), Gaps = 15/198 (7%)
Query: 801 DRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEA 860
D + D + S + D E +S SS S + ++ + SS+ + ++E
Sbjct: 1008 DEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSS---SSSSSSSSSSSSSSSESSSED 1064
Query: 861 REKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYV 920
E+++ S +++ E +PE R AG L +
Sbjct: 1065 EEEEERPAALPSASPPPREVPVPTPAPVEVPVPE--------RVAGSPVTPLPEQEASPA 1116
Query: 921 RTPVVESARPNSTSSREAEPRKGEPA---YENPKKSSEVKV-KEERKEDHDLPPEAPQTH 976
R P S R EP G PA + + SS + + +K + A +
Sbjct: 1117 RPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVV 1176
Query: 977 RASEPPPPNSSSSVHPGP 994
A EPPP + PGP
Sbjct: 1177 PAPEPPPATPPQAKFPGP 1194
Score = 31.2 bits (69), Expect = 6.4
Identities = 49/245 (20%), Positives = 84/245 (34%), Gaps = 35/245 (14%)
Query: 770 NRLHRTPPSFPT--PPPWLKPGELE-RSASAAAHDRDRDVDKRDSSVSKDDKERESVEKR 826
N R PPS+ + PP +P + + R ++ A + ERE V
Sbjct: 400 NTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRT- 458
Query: 827 HSSHPSPAPVLPVNALGHTRSSTEQ---IRAHLNTEAREKDKPKERERDHSESRKDLAAD 883
SP P P + +T + H + ++R + KE+ S D +
Sbjct: 459 -----SPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEE 513
Query: 884 EHKAKE--------GHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSS 935
E + +P GHG P+P V + ++
Sbjct: 514 EENSSMVLGARDTGSEVPSGSGHG-----------PCTPPPAPANFEDVAPTGSGEPGAT 562
Query: 936 REAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPL 995
RE+ G+ ++++ ++ + PP AP + PPPP P L
Sbjct: 563 RESPKANGQNQASPCSSGDDMEISDDDRGGS--PPPAPTPPQQPPPPPPPPPPP--PPYL 618
Query: 996 ASMPM 1000
AS+P+
Sbjct: 619 ASLPL 623
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,634,501
Number of Sequences: 37866
Number of extensions: 4475502
Number of successful extensions: 54263
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 513
Number of HSP's successfully gapped in prelim test: 1910
Number of HSP's that attempted gapping in prelim test: 24858
Number of HSP's gapped (non-prelim): 19091
length of query: 1235
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1121
effective length of database: 13,930,794
effective search space: 15616420074
effective search space used: 15616420074
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.