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Search of human proteins with 187607364
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187607364 tuftelin 1 isoform 2 [Homo sapiens]
(365 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187607364 tuftelin 1 isoform 2 [Homo sapiens] 714 0.0
gi|9910596 tuftelin 1 isoform 1 [Homo sapiens] 701 0.0
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 112 4e-25
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 112 4e-25
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens] 112 4e-25
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 80 4e-15
gi|219689136 coiled-coil domain containing 68 [Homo sapiens] 71 1e-12
gi|13376818 coiled-coil domain containing 68 [Homo sapiens] 71 1e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 65 1e-10
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 62 6e-10
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 62 6e-10
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 62 8e-10
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 62 1e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 60 2e-09
gi|116812628 coiled-coil domain containing 67 [Homo sapiens] 60 2e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 60 3e-09
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 59 7e-09
gi|4503593 epidermal growth factor receptor pathway substrate 15... 59 7e-09
gi|55770834 centromere protein F [Homo sapiens] 59 9e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 58 2e-08
gi|38044112 restin isoform b [Homo sapiens] 58 2e-08
gi|4506751 restin isoform a [Homo sapiens] 58 2e-08
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 58 2e-08
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 57 2e-08
gi|40538794 coiled-coil domain containing 21 [Homo sapiens] 57 2e-08
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 57 2e-08
gi|226495417 coiled-coil domain containing 102A [Homo sapiens] 57 3e-08
gi|188528616 testis specific, 10 [Homo sapiens] 57 3e-08
gi|13376858 testis specific, 10 [Homo sapiens] 57 3e-08
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 57 3e-08
>gi|187607364 tuftelin 1 isoform 2 [Homo sapiens]
Length = 365
Score = 714 bits (1844), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MNGTRNWCTLVDVHPEDQAAAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGR 60
MNGTRNWCTLVDVHPEDQAAAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGR
Sbjct: 1 MNGTRNWCTLVDVHPEDQAAAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGR 60
Query: 61 SGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPN 120
SGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPN
Sbjct: 61 SGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPN 120
Query: 121 GFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQ 180
GFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQ
Sbjct: 121 GFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQ 180
Query: 181 REAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNA 240
REAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNA
Sbjct: 181 REAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNA 240
Query: 241 DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQE 300
DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQE
Sbjct: 241 DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQE 300
Query: 301 LKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSIRISKPPSPKPMPVI 360
LKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSIRISKPPSPKPMPVI
Sbjct: 301 LKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSIRISKPPSPKPMPVI 360
Query: 361 RVVET 365
RVVET
Sbjct: 361 RVVET 365
>gi|9910596 tuftelin 1 isoform 1 [Homo sapiens]
Length = 390
Score = 701 bits (1808), Expect = 0.0
Identities = 365/390 (93%), Positives = 365/390 (93%), Gaps = 25/390 (6%)
Query: 1 MNGTRNWCTLVDVHPEDQAA-------------------------AGRKTYAMVSSHSAG 35
MNGTRNWCTLVDVHPEDQAA AGRKTYAMVSSHSAG
Sbjct: 1 MNGTRNWCTLVDVHPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAG 60
Query: 36 HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI 95
HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI
Sbjct: 61 HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI 120
Query: 96 SSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL 155
SSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL
Sbjct: 121 SSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL 180
Query: 156 AKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGME 215
AKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGME
Sbjct: 181 AKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGME 240
Query: 216 TEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR 275
TEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR
Sbjct: 241 TEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR 300
Query: 276 KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQ 335
KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQ
Sbjct: 301 KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQ 360
Query: 336 ARAKTENPGSIRISKPPSPKPMPVIRVVET 365
ARAKTENPGSIRISKPPSPKPMPVIRVVET
Sbjct: 361 ARAKTENPGSIRISKPPSPKPMPVIRVVET 390
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 112 bits (281), Expect = 4e-25
Identities = 64/182 (35%), Positives = 105/182 (57%), Gaps = 5/182 (2%)
Query: 145 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 204
E +K KLQE +R+H ++ A + + + E++N +Q E +E+K+ +
Sbjct: 240 EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI 299
Query: 205 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 264
GEL R + ME E L ++ E E E+ D +++E+ LE+ A LRE+I
Sbjct: 300 GELDRLIERMEKERHQLQLQLLEHET---EMSGELTD--SDKERYQQLEEASASLRERIR 354
Query: 265 HLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIE 324
HLDDM+ QQ+KV+QM+E++++ K +Q K I +L EKI++LE EN E+ R+++L E
Sbjct: 355 HLDDMVHCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTE 414
Query: 325 KQ 326
Q
Sbjct: 415 TQ 416
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 112 bits (281), Expect = 4e-25
Identities = 64/182 (35%), Positives = 105/182 (57%), Gaps = 5/182 (2%)
Query: 145 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 204
E +K KLQE +R+H ++ A + + + E++N +Q E +E+K+ +
Sbjct: 240 EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI 299
Query: 205 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 264
GEL R + ME E L ++ E E E+ D +++E+ LE+ A LRE+I
Sbjct: 300 GELDRLIERMEKERHQLQLQLLEHET---EMSGELTD--SDKERYQQLEEASASLRERIR 354
Query: 265 HLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIE 324
HLDDM+ QQ+KV+QM+E++++ K +Q K I +L EKI++LE EN E+ R+++L E
Sbjct: 355 HLDDMVHCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTE 414
Query: 325 KQ 326
Q
Sbjct: 415 TQ 416
Score = 37.0 bits (84), Expect = 0.028
Identities = 58/294 (19%), Positives = 125/294 (42%), Gaps = 29/294 (9%)
Query: 30 SSHSAGHSLASELVES-HDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCL 88
SS A + E+ + + +EE ++ + S +K E + + S ++ I+EA +
Sbjct: 229 SSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEK---EALLEETNSFLKAIEEANKKM 285
Query: 89 QKLREDISSKLDRNLGD------SLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINE 142
Q + K D+ +G+ + ++ Q+ L+ ++ L S E + E
Sbjct: 286 QAAEISLEEK-DQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEE 344
Query: 143 DVESLRKTVQDL--LAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQK 200
SLR+ ++ L + Q+ K + + + +++ +Q + + + +++
Sbjct: 345 ASASLRERIRHLDDMVHCQQKKVKQMVE------EIESLKKKLQQKQLLILQLLEKISFL 398
Query: 201 EAEVGELQRRLLGMETEHQALLAKVREGEVALEEL-----RSNNADCQAEREKAATLEKE 255
E E ELQ RL + + RE V + L R N++ ++ + + E
Sbjct: 399 EGENNELQSRLDYLTETQAKTEVETREIGVGCDLLPRLPFRQNDSSSHCQKS-GSPISSE 457
Query: 256 VAGLREKIHHLDDMLKSQQRKVRQMIEQL---QNSKAVIQSKDATIQELKEKIA 306
R+K HLDD+ ++ + M QL + S A+ + + +E++ K+A
Sbjct: 458 ERRRRDK-QHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLA 510
>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
Length = 466
Score = 112 bits (281), Expect = 4e-25
Identities = 64/182 (35%), Positives = 105/182 (57%), Gaps = 5/182 (2%)
Query: 145 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 204
E +K KLQE +R+H ++ A + + + E++N +Q E +E+K+ +
Sbjct: 240 EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI 299
Query: 205 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 264
GEL R + ME E L ++ E E E+ D +++E+ LE+ A LRE+I
Sbjct: 300 GELDRLIERMEKERHQLQLQLLEHET---EMSGELTD--SDKERYQQLEEASASLRERIR 354
Query: 265 HLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIE 324
HLDDM+ QQ+KV+QM+E++++ K +Q K I +L EKI++LE EN E+ R+++L E
Sbjct: 355 HLDDMVHCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTE 414
Query: 325 KQ 326
Q
Sbjct: 415 TQ 416
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 79.7 bits (195), Expect = 4e-15
Identities = 47/139 (33%), Positives = 77/139 (55%), Gaps = 5/139 (3%)
Query: 145 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 204
E +K KLQE +R+H ++ A + + + E++N +Q E +E+K+ +
Sbjct: 240 EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI 299
Query: 205 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 264
GEL R + ME E L ++ E E E+ D +++E+ LE+ A LRE+I
Sbjct: 300 GELDRLIERMEKERHQLQLQLLEHET---EMSGELTD--SDKERYQQLEEASASLRERIR 354
Query: 265 HLDDMLKSQQRKVRQMIEQ 283
HLDDM+ QQ+KV+QM+E+
Sbjct: 355 HLDDMVHCQQKKVKQMVEE 373
>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 71.2 bits (173), Expect = 1e-12
Identities = 61/281 (21%), Positives = 129/281 (45%), Gaps = 38/281 (13%)
Query: 66 IHEKNINQLKSEVQYIQEARNCLQKLR----------EDISSKLDRNLGDSLHRQE---- 111
++E + E +Y+++ R LQK+R + + KLD +L +
Sbjct: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEM 81
Query: 112 ------IQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVES----LRKTVQDLLAKLQ-- 159
+ ++++K G + + + E+ LR Q L Q
Sbjct: 82 DPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQ 141
Query: 160 --EAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 217
E +++ + +V +++ +Q L + +++E+K +++ EL+ + ME E
Sbjct: 142 SEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKE 201
Query: 218 HQALLAKVREGEVALEELRSN---NADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQ 274
+ LL + E L +L+S+ CQ L++E++ L+E+I HL ++ SQ
Sbjct: 202 KRTLLERKLSLENKLLQLKSSATYGKSCQ-------DLQREISILQEQISHLQFVIHSQH 254
Query: 275 RKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEM 315
+ +R +I++++ K ++ +D I+ L+EK+ LEA+N E+
Sbjct: 255 QNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKEL 295
>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 71.2 bits (173), Expect = 1e-12
Identities = 61/281 (21%), Positives = 129/281 (45%), Gaps = 38/281 (13%)
Query: 66 IHEKNINQLKSEVQYIQEARNCLQKLR----------EDISSKLDRNLGDSLHRQE---- 111
++E + E +Y+++ R LQK+R + + KLD +L +
Sbjct: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEM 81
Query: 112 ------IQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVES----LRKTVQDLLAKLQ-- 159
+ ++++K G + + + E+ LR Q L Q
Sbjct: 82 DPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQ 141
Query: 160 --EAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 217
E +++ + +V +++ +Q L + +++E+K +++ EL+ + ME E
Sbjct: 142 SEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKE 201
Query: 218 HQALLAKVREGEVALEELRSN---NADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQ 274
+ LL + E L +L+S+ CQ L++E++ L+E+I HL ++ SQ
Sbjct: 202 KRTLLERKLSLENKLLQLKSSATYGKSCQ-------DLQREISILQEQISHLQFVIHSQH 254
Query: 275 RKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEM 315
+ +R +I++++ K ++ +D I+ L+EK+ LEA+N E+
Sbjct: 255 QNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKEL 295
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 64.7 bits (156), Expect = 1e-10
Identities = 51/268 (19%), Positives = 122/268 (45%), Gaps = 17/268 (6%)
Query: 71 INQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVVLEKPNGFSQSPTA 128
+NQ + E + QE + +Q+ E I + + R + + RQE +++ EK +
Sbjct: 282 LNQQQEEKMWRQEEK--IQEREEKIQEQEEKIREQEEKMRRQE-EMMWEKEEKMRRQEEM 338
Query: 129 LYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNV 188
++ ++ + E + K + + +E K + Q E + R + + +
Sbjct: 339 MWEKEEKIRE-LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 189 ALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVAL-----------EELRS 237
++ +E+ ++++E ++GE + ++ E E Q K+R E + E++R
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 238 NNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDAT 297
Q + EK E ++ K+ ++ ++ Q+ K+R+ ++++ + I+ ++
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517
Query: 298 IQELKEKIAYLEAENLEMHDRMEHLIEK 325
+QE +EK+ E + E ++M+ EK
Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Score = 60.5 bits (145), Expect = 2e-09
Identities = 55/273 (20%), Positives = 124/273 (45%), Gaps = 24/273 (8%)
Query: 70 NINQLKSEV---------QYIQEARNCLQKLREDISSKL-----DRNLGDSLHRQEIQVV 115
N+ +LK ++ Q +Q + L K + +S+KL + L + L++Q+ + +
Sbjct: 231 NVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKM 290
Query: 116 LEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVT 175
+ + + E + I E E +R+ + + K ++ +RQ + E
Sbjct: 291 WRQEEKIQEREEKIQ----EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 176 LSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLA---KVREGEVAL 232
++ EQ + Q E+ + E+K E + Q + M + + + K+RE E +
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406
Query: 233 EELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQ 292
+E + + EK E+E+ EK+ ++ ++ Q++K+R+ E+++ + ++Q
Sbjct: 407 QEQEEKMGE---QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463
Query: 293 SKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 325
++ + E + K+ EA+ E ++M EK
Sbjct: 464 EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK 496
Score = 54.3 bits (129), Expect = 2e-07
Identities = 53/275 (19%), Positives = 127/275 (46%), Gaps = 19/275 (6%)
Query: 50 EEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR 109
E+I + K R ++M+ EK +++ + + + E +++L E + + ++ R
Sbjct: 309 EKIREQEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKIRELEEKMHEQ-EKIREQEEKR 366
Query: 110 QEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDC 169
QE + + E+ Q I E E +R+ Q+ + + QE K Q
Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEK-----IREQEEKIRE--QEEMMQEQEEKMGEQ--- 416
Query: 170 VAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKV--RE 227
E + + E ++ ++R+E+++ ++E ++ E + ++ E Q K+ +E
Sbjct: 417 ---EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 228 GEVALEELRSNNADCQAER--EKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQ 285
G++ +E + + + R EK EK++ EKI ++M++ Q+ K+ + E++
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533
Query: 286 NSKAVIQSKDATIQELKEKIAYLEAENLEMHDRME 320
+ +Q ++ ++ +EK+ E + ++M+
Sbjct: 534 EQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 51.2 bits (121), Expect = 1e-06
Identities = 72/342 (21%), Positives = 139/342 (40%), Gaps = 55/342 (16%)
Query: 10 LVDVHPEDQAAAGRK------------TYAMVSSHSAGHSLASELVESHDGHEEIIKVYL 57
L D HP+ + G T ++ HS E SH H+E ++ L
Sbjct: 55 LTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQ-HQEALRREL 113
Query: 58 KGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLE 117
+ + I +L+ + Y Q A L+ D+ S+L + +
Sbjct: 114 EAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSW-------------K 160
Query: 118 KPNGFSQSPTALYSSPPEVDTCINE--------DVESLRKTVQD-----LLAKLQEAKRQ 164
Q+ +A+ + + D I E +E R T+ D AKLQE +
Sbjct: 161 FAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQL 220
Query: 165 HQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAK 224
+S+ ++ + +R+ E++ + L ++ Q +AE L + L + + QA +
Sbjct: 221 VESEKSEIQLNVKELKRKLERAKLLLPQQ-----QLQAEADHLGKELQSVSAKLQA---Q 272
Query: 225 VREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQL 284
V E E+ N Q + EK E+++ EKI ++ ++ Q+ K+R+ E +
Sbjct: 273 VEENELW-------NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMM 325
Query: 285 QNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQ 326
+ ++ ++ + E +EKI LE E + +++ EK+
Sbjct: 326 WEKEEKMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQEEKR 366
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.4 bits (150), Expect = 6e-10
Identities = 63/289 (21%), Positives = 136/289 (47%), Gaps = 31/289 (10%)
Query: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 122
D+ + EKN +L+ +++ ++ ++ +Q +D+ KL+R L +Q++QV ++
Sbjct: 213 DEELKEKNA-ELQEKLRLVESEKSEIQLNVKDLKRKLER-AQLLLPQQQLQVEADRLGKE 270
Query: 123 SQSPTALYSSPPEVDTCIN--------------EDVESLRKTV--QDLLAKLQEAKRQHQ 166
QS +A + E + N E ++ + + Q+L + QE K Q
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 167 SDCV--------AFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEH 218
+ + E + R + + + ++ +E+++ ++E ++ E ++ E E
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 219 QALLAKVREGEVALEE-LRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKV 277
K+RE E +E + + + EK E+E+ EKI L++M++ Q+ K+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 278 RQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQ 326
R++ E++Q + +Q ++ IQ +EKI E E R E L++++
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKI----QEQEEKTWRQEKLLKQE 495
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/278 (17%), Positives = 128/278 (46%), Gaps = 28/278 (10%)
Query: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVVLEKPN 120
++ I E+ + E++ I+E + + E + + + R D + RQE + + E+
Sbjct: 303 EEKIQEQEEKMCEQELK-IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE-EKIREQEE 360
Query: 121 GFSQSPTALYSSPPEV---DTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLS 177
+ ++ ++ D I E E + + Q+ + QE KRQ + +
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWR--QEEKIREQEEKRQEK---------MW 409
Query: 178 RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEE--- 234
R +++ + + ++ +E+ + ++E ++ EL+ + E + + + K++E E ++E
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469
Query: 235 -LRSNNADCQAEREKAATLEK------EVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNS 287
++ Q + EK EK ++ EK+ ++ + Q+ K+++ E++Q
Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
Query: 288 KAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 325
+ ++ ++ + + +EK+ E E+ +R+ L +K
Sbjct: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 37.0 bits (84), Expect = 0.028
Identities = 37/188 (19%), Positives = 80/188 (42%), Gaps = 27/188 (14%)
Query: 165 HQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAK 224
H V + + +E + ++ L R E+ + + ELQ +L +E+E +
Sbjct: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
Query: 225 VREGEVALE--------------------ELRSNNADCQAEREK-------AATLEKEVA 257
V++ + LE EL+S +A QA+ E+ E+++
Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
Query: 258 GLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHD 317
EKI ++ + Q+ K+R+ E++ + + ++ I+E ++K+ E + E +
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 318 RMEHLIEK 325
++ EK
Sbjct: 361 KIREQEEK 368
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.4 bits (150), Expect = 6e-10
Identities = 63/289 (21%), Positives = 136/289 (47%), Gaps = 31/289 (10%)
Query: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 122
D+ + EKN +L+ +++ ++ ++ +Q +D+ KL+R L +Q++QV ++
Sbjct: 213 DEELKEKNA-ELQEKLRLVESEKSEIQLNVKDLKRKLER-AQLLLPQQQLQVEADRLGKE 270
Query: 123 SQSPTALYSSPPEVDTCIN--------------EDVESLRKTV--QDLLAKLQEAKRQHQ 166
QS +A + E + N E ++ + + Q+L + QE K Q
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 167 SDCV--------AFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEH 218
+ + E + R + + + ++ +E+++ ++E ++ E ++ E E
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 219 QALLAKVREGEVALEE-LRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKV 277
K+RE E +E + + + EK E+E+ EKI L++M++ Q+ K+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 278 RQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQ 326
R++ E++Q + +Q ++ IQ +EKI E E R E L++++
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKI----QEQEEKTWRQEKLLKQE 495
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/278 (17%), Positives = 128/278 (46%), Gaps = 28/278 (10%)
Query: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVVLEKPN 120
++ I E+ + E++ I+E + + E + + + R D + RQE + + E+
Sbjct: 303 EEKIQEQEEKMCEQELK-IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE-EKIREQEE 360
Query: 121 GFSQSPTALYSSPPEV---DTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLS 177
+ ++ ++ D I E E + + Q+ + QE KRQ + +
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWR--QEEKIREQEEKRQEK---------MW 409
Query: 178 RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEE--- 234
R +++ + + ++ +E+ + ++E ++ EL+ + E + + + K++E E ++E
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469
Query: 235 -LRSNNADCQAEREKAATLEK------EVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNS 287
++ Q + EK EK ++ EK+ ++ + Q+ K+++ E++Q
Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
Query: 288 KAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 325
+ ++ ++ + + +EK+ E E+ +R+ L +K
Sbjct: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 36.6 bits (83), Expect = 0.036
Identities = 37/188 (19%), Positives = 80/188 (42%), Gaps = 27/188 (14%)
Query: 165 HQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAK 224
H V + + +E + ++ L R E+ + + ELQ +L +E+E +
Sbjct: 181 HFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
Query: 225 VREGEVALE--------------------ELRSNNADCQAEREK-------AATLEKEVA 257
V++ + LE EL+S +A QA+ E+ E+++
Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
Query: 258 GLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHD 317
EKI ++ + Q+ K+R+ E++ + + ++ I+E ++K+ E + E +
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 318 RMEHLIEK 325
++ EK
Sbjct: 361 KIREQEEK 368
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 62.0 bits (149), Expect = 8e-10
Identities = 61/293 (20%), Positives = 131/293 (44%), Gaps = 35/293 (11%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT 127
E I QLK E + E N + ++E++ K S ++ V L+ S+
Sbjct: 1338 ESCITQLKKE---LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEA 1394
Query: 128 ALYSSPPE------------------VDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDC 169
A+ S + VDT E + +L + V D K E K++ QS
Sbjct: 1395 AISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQ-VDDWSNKFSEWKKKAQS-- 1451
Query: 170 VAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGE 229
+++Q ++ + L+ + +K+ ++ L+ L L ++ + +
Sbjct: 1452 -----RFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDK 1506
Query: 230 VALEELRSN-NADCQAEREKAATLEKEVAGLREKIHHLDDMLKS--QQRKV--RQMIEQL 284
+E+ SN + +++ + LE + +I L+++LK+ QQ+ + ++++++L
Sbjct: 1507 SKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKL 1566
Query: 285 QNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQAR 337
Q+ + + + KD ++E +EKI LE + M +E +K++ H N S +++
Sbjct: 1567 QHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE-TKKKELEHVNLSVKSK 1618
Score = 59.7 bits (143), Expect = 4e-09
Identities = 66/305 (21%), Positives = 138/305 (45%), Gaps = 31/305 (10%)
Query: 51 EIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKL-------REDISSKLDRNL 103
++ + Y +E+ + QL+ ++ ++ R L K ++D+ ++LD +
Sbjct: 801 DVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAH- 859
Query: 104 GDSLHRQEIQVVLEKPNGFSQ----SPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQ 159
+ Q++ LEK N + S T +Y S E E + + ++++ +++
Sbjct: 860 --KIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMR 917
Query: 160 EAKRQH----QSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGE-LQRRLLGM 214
E +++ A E ++ E E +++ ++V+QK E+ E L+++LL
Sbjct: 918 EGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQ 977
Query: 215 ET------EHQALLAKVREGEV---ALEELRSNNADCQAEREKAATLEKEVAGLREKIHH 265
E E+ AL +E + LE ++N+A + T +KE ++H
Sbjct: 978 EAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHR 1037
Query: 266 --LDDMLKSQQRKVRQMIEQLQNSKAV-IQSKDATIQELKEKIAYLEAENLEMHDRMEHL 322
L+D++ ++K+ Q E+LQ + +Q K+ + ELK+KI E EM+ + L
Sbjct: 1038 RELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1097
Query: 323 IEKQI 327
E+ +
Sbjct: 1098 KEEGV 1102
Score = 54.7 bits (130), Expect = 1e-07
Identities = 55/276 (19%), Positives = 130/276 (47%), Gaps = 42/276 (15%)
Query: 66 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQS 125
+ + + L SE+ + +AR+ KL E++S D+ D + +QE++ +++ Q
Sbjct: 681 VKQTELESLSSELSEVLKARH---KLEEELSVLKDQT--DKM-KQELEAKMDEQKNHHQQ 734
Query: 126 PTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAK----------RQHQSDCVAFEVT 175
+VD+ I E S+++T + L ++ + + ++HQ+ E
Sbjct: 735 ---------QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEAD 785
Query: 176 LSRYQREAEQSNVALQ-------REEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREG 228
+ R + E +Q++ L ++ + E ++ +LQ++LL +ETE L +V E
Sbjct: 786 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV 845
Query: 229 EVALEELRSN-NADCQAEREKAATLEKEVAGLREKIHHLDDMLKS-------QQRKVRQM 280
E +++ + +A ++ LEK+ + + +K+ L + +S +Q + +Q+
Sbjct: 846 EAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI 905
Query: 281 IEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMH 316
+ + +N ++Q ++ +E++ L A+ +H
Sbjct: 906 LVEKEN--MILQMREGQKKEIEILTQKLSAKEDSIH 939
Score = 53.1 bits (126), Expect = 4e-07
Identities = 74/332 (22%), Positives = 140/332 (42%), Gaps = 27/332 (8%)
Query: 11 VDVHPEDQAAAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKN 70
VD +++ +A + + S A H + +++ L+ +S + ++
Sbjct: 1421 VDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQ 1480
Query: 71 INQLKSEVQYIQEARNCLQKLREDISSKLDR---NLGDSLHRQEIQVVLEKPNGFSQSPT 127
IN LK E+ + +CL+ ED SK+++ NL L Q + ++E + +Q T
Sbjct: 1481 INLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTAR-IMELEDHITQK-T 1538
Query: 128 ALYSSPPEVDTCINEDVESLRKTVQDLLAKLQE-------AKRQHQSDCVAFEVTLSRYQ 180
S EV N+ + K + L QE ++ + + E + +
Sbjct: 1539 IEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMK 1598
Query: 181 REAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKV-REGEVALEELRSNN 239
E E L+ V+ KE E+ L+ RL E+E A LA++ R+ E + ++
Sbjct: 1599 AELETKKKELEHVNLSVKSKEEELKALEDRL---ESESAAKLAELKRKAEQKIAAIKKQL 1655
Query: 240 ADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATI- 298
E+E E+ G + L+ L+ ++R+V + E+L K+V S+ T+
Sbjct: 1656 LSQMEEKE-----EQYKKGTESHLSELNTKLQEREREVHILEEKL---KSVESSQSETLI 1707
Query: 299 --QELKEKIAYLEAENLEMHDRMEHLIEKQIS 328
+ K AY E E + ++ E++IS
Sbjct: 1708 VPRSAKNVAAYTEQEEADSQGCVQKTYEEKIS 1739
Score = 46.6 bits (109), Expect = 4e-05
Identities = 65/274 (23%), Positives = 121/274 (44%), Gaps = 37/274 (13%)
Query: 82 QEARNCLQKLREDISSKLDRNLGDS-----LHRQEI-QVVLEKPNGFSQSPTALYSSPPE 135
Q+ + ++KLRE + + L D H +E+ + LEK + +L S E
Sbjct: 636 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSE 695
Query: 136 VDTC---INEDVESLR----KTVQDLLAKLQEAKRQHQSDCVAF----EVTLSRYQR--- 181
V + E++ L+ K Q+L AK+ E K HQ + EV++ R ++
Sbjct: 696 VLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALK 755
Query: 182 -EAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNA 240
+ Q + L+ + +++ +A V L+ + E E Q AK L+ +S +
Sbjct: 756 DQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAK-------LDVFQSYQS 808
Query: 241 DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQE 300
A E+ E+++A L++K L D+ + +Q+ E K V DA +
Sbjct: 809 ---ATHEQTKAYEEQLAQLQQK---LLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQ 862
Query: 301 LKEKIAYLEAENLEMHDRMEHL---IEKQISHGN 331
+++ + LE +N EM +++ L E ++ GN
Sbjct: 863 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 896
Score = 46.6 bits (109), Expect = 4e-05
Identities = 68/317 (21%), Positives = 132/317 (41%), Gaps = 29/317 (9%)
Query: 24 KTYAMVSSHSAGHSLASELVESHDGH--EEIIKVYLKGRSGDKMIHEKNINQLKSEVQYI 81
K M ++SAG S A +E++ E + +V+ + + I EK +NQ E+Q I
Sbjct: 1002 KMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEI 1061
Query: 82 QEARNCLQKLREDISSKLDRNLGDSLHRQEI--QVVLEKPNGFSQSPTALYSSPPEVDTC 139
E + LQ+ ++++ + L ++E+ ++ K G Q DT
Sbjct: 1062 HEIQ--LQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQ------------DTT 1107
Query: 140 INEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQ 199
+NE E L++ + + Q+ + + ++ EV L++ +E L + E+
Sbjct: 1108 LNELQEQLKQKSAHVNSLAQD-ETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1166
Query: 200 KEAEVGELQRRLLGMETEHQALLAKVREGEVALEE--LRSNNADCQAEREKAATLEKEVA 257
+ +V EL +L + E Q+L + + +LE+ L + + +K A
Sbjct: 1167 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEA 1226
Query: 258 GLREKIHHLDDMLKSQQRKVRQMIEQLQNS----KAVIQSKDATIQELKEKIAYLEAE-- 311
L K + L ++ S+ + I Q+ K + K T+ EL+ ++ L E
Sbjct: 1227 LLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQN 1286
Query: 312 --NLEMHDRMEHLIEKQ 326
N+ L EK+
Sbjct: 1287 TLNISFQQATHQLEEKE 1303
Score = 43.5 bits (101), Expect = 3e-04
Identities = 49/213 (23%), Positives = 89/213 (41%), Gaps = 21/213 (9%)
Query: 135 EVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREE 194
E+D+C+ E R +++L +K ++ + Q D L E + + +Q +
Sbjct: 1858 ELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPK- 1916
Query: 195 DRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNA--------DCQAER 246
+ EA+ +L+ +L G E E Q L ++ + L LR + + ER
Sbjct: 1917 -LLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQER 1975
Query: 247 EKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIA 306
E+ E+E L+ + LK R+ + Q + Q + TI+E K
Sbjct: 1976 EEKIKQEQEDLELKH-----NSTLKQLMREFNTQLAQKE------QELEMTIKETINKAQ 2024
Query: 307 YLEAENLEMHDRMEHLIEKQISHGNFSTQARAK 339
+EAE LE H + + K+I+ + + AK
Sbjct: 2025 EVEAELLESHQEETNQLLKKIAEKDDDLKRTAK 2057
Score = 41.2 bits (95), Expect = 0.001
Identities = 47/266 (17%), Positives = 109/266 (40%), Gaps = 47/266 (17%)
Query: 33 SAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLR 92
S H + +L+ + + ++ L G +K K I +L+ +++ +++ Q+
Sbjct: 1908 SKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH---QQEL 1964
Query: 93 EDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQ 152
E + + D+ + + +++ + L+ + Q E +T + + + L T++
Sbjct: 1965 EILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMR-------EFNTQLAQKEQELEMTIK 2017
Query: 153 DLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLL 212
+ + K QE + + L +Q E Q + ++D +++ E+
Sbjct: 2018 ETINKAQEVEAE----------LLESHQEETNQLLKKIAEKDDDLKRTAKRYEEI----- 2062
Query: 213 GMETEHQALLAKVREGEVALEELRSNNADCQAEREKAAT-------LEKEVA-------- 257
++ + + AKVR+ + LEEL+ + E L+ ++A
Sbjct: 2063 -LDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISD 2121
Query: 258 ------GLREKIHHLDDMLKSQQRKV 277
RE+IH+L+D LK ++ V
Sbjct: 2122 SKLKEQEFREQIHNLEDRLKKYEKNV 2147
Score = 40.0 bits (92), Expect = 0.003
Identities = 68/324 (20%), Positives = 129/324 (39%), Gaps = 57/324 (17%)
Query: 35 GHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEK-NINQLKSEVQYIQEARNCLQKLRE 93
GH L EL E + + I+ +++ G I K N+ + +VQ + + ++ E
Sbjct: 1795 GH-LQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILE 1853
Query: 94 DISSKLDRNL--GDSLHRQEIQVVL---EKPNGFSQ-----SPTALYSSPPE-------V 136
+LD L +HR E++ + EK Q PT L E V
Sbjct: 1854 QKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLV 1913
Query: 137 DTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREED- 195
+ ++E+ ++ LA + K++ + V + L ++E +Q L++E D
Sbjct: 1914 QPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQ 1973
Query: 196 ------RVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAER--- 246
+ EQ++ E+ M + L K +E E+ ++E + + +AE
Sbjct: 1974 EREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLES 2033
Query: 247 -------------------EKAATLEKEVAGLRE-----KIHHLDDMLKSQQRKVRQMIE 282
++ A +E+ RE K+ L L+ Q+K +Q +E
Sbjct: 2034 HQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLE 2093
Query: 283 QLQNSKAVIQSKDATIQELKEKIA 306
Q +N + + TI EL+ ++A
Sbjct: 2094 QEENP----GNDNVTIMELQTQLA 2113
Score = 39.7 bits (91), Expect = 0.004
Identities = 74/311 (23%), Positives = 133/311 (42%), Gaps = 60/311 (19%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT 127
E+ +LK+E+ E ++K E+ L + L S +QE+ V++K
Sbjct: 427 EEARRKLKAEMD---EQIKTIEKTSEEERISLQQEL--SRVKQEVVDVMKK--------- 472
Query: 128 ALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDC-VAFEVTLSRYQREAEQS 186
SS ++ + L + Q+L KLQ +R+ Q VA E + S Y +
Sbjct: 473 ---SSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK----- 524
Query: 187 NVALQREEDRVEQKEAEVGELQRRLLGMETEH---------QALLAKVREGEVALEELRS 237
+ +E+++ E E ELQ++ + E+E+ + ++ E E +LE+
Sbjct: 525 ---ISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQ 581
Query: 238 NNAD--------CQAEREKAATLEKEVAGLREKIHHLDDMLKSQQ-----RKVRQMIEQL 284
N + +AE+ K KE+ + EK + LK QQ K++ + +Q
Sbjct: 582 ENKNQSKDLAVHLEAEKNKH---NKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQY 638
Query: 285 QNSKAVIQSKDATIQE--LKEKIAYLEAENLEMHDR-MEHLIEKQISHGNFSTQ------ 335
Q ++ K +E LK+K +A EM+++ +E L KQ + S++
Sbjct: 639 QTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLK 698
Query: 336 ARAKTENPGSI 346
AR K E S+
Sbjct: 699 ARHKLEEELSV 709
Score = 33.5 bits (75), Expect = 0.31
Identities = 55/303 (18%), Positives = 122/303 (40%), Gaps = 48/303 (15%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR-----QEIQVVLEKPNGF 122
E++++ + + + A LQ+ ++ + L ++ SL R +E+Q+ +
Sbjct: 147 ERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHL 206
Query: 123 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 182
+ A + + + V L++ +++ + K Q + A EV E
Sbjct: 207 QEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQA-EVFTKEENPE 265
Query: 183 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 242
++ V ED K E LQ+R+ E LL + +E ++S+ C
Sbjct: 266 SDGEPVV----EDGTSVKTLET--LQQRVKRQEN----LLKRCKE------TIQSHKEQC 309
Query: 243 QAEREKAATLEKEVAGLREKIHHLDDM-------LKSQQRKVRQMIEQLQNSKAVI---- 291
+ L++++ +++ + D+ L +Q R + +IEQL+ K ++
Sbjct: 310 TLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAET 369
Query: 292 --------QSKDATIQELKEKIAYLEAENLEMHDRME-------HLIEKQISHGNFSTQA 336
+ K+ I +L+ +I + + E+ ++ E +EK +S + +A
Sbjct: 370 KRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEA 429
Query: 337 RAK 339
R K
Sbjct: 430 RRK 432
Score = 29.3 bits (64), Expect = 5.8
Identities = 53/278 (19%), Positives = 107/278 (38%), Gaps = 39/278 (14%)
Query: 50 EEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR 109
EE +K +S ++ N Q +++ C+QK E+ S L RNL
Sbjct: 1692 EEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNL------ 1745
Query: 110 QEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDC 169
++ L E + ++ E +R Q+ L KL+ A+ + D
Sbjct: 1746 -------------TEKEKLLQRVGQEKEETVSSHFE-MRCQYQERLIKLEHAEAKQHED- 1790
Query: 170 VAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGE 229
+ + Q E E+ N + +KE +Q + +E + ++E E
Sbjct: 1791 ---QSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAK-QNLENVFDDVQKTLQEKE 1846
Query: 230 VA---LEELRSNNADCQAEREKAATLE-KEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQ 285
+ LE+ C +++ +E +E+ EK+ L M + K +++E+
Sbjct: 1847 LTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQM--DGRNKPTELLEENT 1904
Query: 286 NSKA--------VIQSKDATIQELKEKIAYLEAENLEM 315
K+ ++ + +A +L+ K+A E E ++
Sbjct: 1905 EEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKL 1942
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 61.6 bits (148), Expect = 1e-09
Identities = 66/283 (23%), Positives = 128/283 (45%), Gaps = 16/283 (5%)
Query: 50 EEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR 109
EE+ K+ K + ++M E+ K+E++ +Q+ +K E + ++ R +SL R
Sbjct: 604 EELEKLESKRKLIEEM--EEKQKSDKAELERMQQEVETQRKETEIVQLQI-RKQEESLKR 660
Query: 110 QEIQV------VLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKR 163
+ + +L + F + E++ E VQ+ L +L+E
Sbjct: 661 RSFHIENKLKDLLAEKEKFEEERLR---EQQEIELQKKRQEEETFLRVQEELQRLKELNN 717
Query: 164 QHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLA 223
+++ L + Q+E ++ L+ E+ R+E++E E L L E Q ++
Sbjct: 718 NEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQ 777
Query: 224 KVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDD-MLKSQQRKVRQMIE 282
+R GEV + + D + RE +++ AG E L+ L+ + K RQ+++
Sbjct: 778 LLRRGEV--QWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVK 835
Query: 283 QLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 325
+ K ++Q KD +E++E+ LE E HD+ L+EK
Sbjct: 836 LVNLEKDLVQQKDILKKEVQEEQEILECLKCE-HDKESRLLEK 877
Score = 28.5 bits (62), Expect = 9.9
Identities = 49/260 (18%), Positives = 106/260 (40%), Gaps = 43/260 (16%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLR------------EDISSKLDRNLGDSLHRQEIQVV 115
EK + + + ++ Q N LQKL+ E+ K ++ + +S +Q+ + +
Sbjct: 946 EKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREAL 1005
Query: 116 LEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVT 175
+ +AL + + + ++E R+ LA L R+
Sbjct: 1006 ERALARLERRHSAL-----QRHSTLGMEIEEQRQK----LASLNSGSREQ---------- 1046
Query: 176 LSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALL-AKVREGEVALEE 234
S Q E AL+++++R+E + ++ + + G++ +H L KV + +
Sbjct: 1047 -SGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSA 1105
Query: 235 LRSNNADCQAEREKAATLEKEVAGLREKIHHL--------DDMLKSQQRKVRQMIE-QLQ 285
+S+ R A +E+EV + +H + D +K ++ I+ +L+
Sbjct: 1106 EKSHLVPLMDARIN-AYIEEEVQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKLK 1164
Query: 286 NSKAVIQSKDATIQELKEKI 305
+ V +S A +LK+ I
Sbjct: 1165 YERMVSRSLGANPDDLKDPI 1184
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 60.5 bits (145), Expect = 2e-09
Identities = 49/272 (18%), Positives = 128/272 (47%), Gaps = 9/272 (3%)
Query: 58 KGRSGDKMIHEKN--INQLKSEVQYIQEARNCLQKLRED--ISSKLDRNLGDSLHRQEIQ 113
K R ++M+ EK I +L+ ++ ++ R +K +E+ I + R ++ ++ +
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 114 VVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFE 173
+ E+ + ++ ++ E R+ +++ QE K + Q + +
Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR--QEEKIREQEEIWRQK 542
Query: 174 VTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALE 233
+ + + + + R+E+++ +E ++ E + ++ E + + K+RE E E
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE---E 599
Query: 234 ELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS 293
++R Q + EK E+++ EK+ ++ ++ Q+ K+R+ ++++ + I+
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 659
Query: 294 KDATIQELKEKIAYLEAENLEMHDRMEHLIEK 325
++ +QE +EK+ E + E ++M+ EK
Sbjct: 660 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Score = 56.2 bits (134), Expect = 4e-08
Identities = 44/256 (17%), Positives = 120/256 (46%), Gaps = 11/256 (4%)
Query: 66 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVVLEKPNGFS 123
++++ ++ + + IQE +Q+ E I + + R + + RQE +++ EK
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE-EMMWEKEEKMR 413
Query: 124 QSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREA 183
+ ++ ++ E + + +++L K+ E ++ + + E R Q +
Sbjct: 414 RQEEMMWEKEEKMRRQ-EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 472
Query: 184 EQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQ 243
++ + R+E+++ ++E ++ E + ++ E K+ E E EE + +
Sbjct: 473 QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEE-------KIHEQEKIREEEKRQEQEEM 525
Query: 244 AEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKE 303
+E+ ++E+ +EKIH ++ ++ Q+ K+ + E++ + + I+ ++ + +E
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Query: 304 KIAYLEAENLEMHDRM 319
KI E + E +++
Sbjct: 586 KIREQEEKIREQEEKI 601
Score = 53.5 bits (127), Expect = 3e-07
Identities = 71/357 (19%), Positives = 139/357 (38%), Gaps = 47/357 (13%)
Query: 10 LVDVHPEDQAAAGRK------------TYAMVSSHSAGHSLASELVESHDGHEEIIKVYL 57
L D HP+ + G T ++ HS E SH H+E ++ L
Sbjct: 128 LTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQ-HQEALRREL 186
Query: 58 KGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLE 117
+ + I +L+ + Y Q A L+ D+ S+L + +
Sbjct: 187 EAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSW-------------K 233
Query: 118 KPNGFSQSPTALYSSPPEVDTCINE--------DVESLRKTVQD-----LLAKLQEAKRQ 164
Q+ +A+ + + D I E +E R T+ D AKLQE +
Sbjct: 234 FAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQL 293
Query: 165 HQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAK 224
+S+ ++ + +R+ E++ + L ++ Q +AE L + L + + QA +
Sbjct: 294 VESEKSEIQLNVKELKRKLERAKLLLPQQ-----QLQAEADHLGKELQSVSAKLQA---Q 345
Query: 225 VREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQL 284
V E E+ + + EK E+++ EKI ++ ++ Q+ K+R+ E +
Sbjct: 346 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 405
Query: 285 QNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTE 341
+ ++ ++ + E +EK+ E E +++ L EK Q + E
Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 462
Score = 51.6 bits (122), Expect = 1e-06
Identities = 41/191 (21%), Positives = 89/191 (46%), Gaps = 23/191 (12%)
Query: 140 INEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQ 199
I+E E +RK + + QE K Q + + RE E+ + R+E+++ +
Sbjct: 545 IHEQEEKIRKQEEKMWR--QEEKMHDQEEKI----------REQEEK---VWRQEEKIRE 589
Query: 200 KEAEVGELQRRLLGMETEHQALLAKVREGEVAL----EELRSNNADCQAEREKAATLEKE 255
+E ++ E + ++ E Q K+ E E + E+++ + + EK EK+
Sbjct: 590 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK 649
Query: 256 VAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI----AYLEAE 311
+ EKI ++M++ Q+ K+ + E++ + +Q ++ ++ +EK+ L +
Sbjct: 650 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709
Query: 312 NLEMHDRMEHL 322
+M + EHL
Sbjct: 710 EEKMQEHQEHL 720
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/231 (17%), Positives = 104/231 (45%), Gaps = 12/231 (5%)
Query: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 122
++ IHE+ + + + Q +E +K+RE + + +H QE ++ ++ +
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK---EKIHEQEEKIRKQEEKMW 560
Query: 123 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 182
Q + + I E E + + + + + ++ + Q + E+T + ++
Sbjct: 561 RQE-----EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615
Query: 183 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 242
EQ ++EE EQ+E ++ + ++ E + + K+RE E ++E +
Sbjct: 616 GEQEEKMCEQEEKMQEQEE-KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE- 673
Query: 243 QAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS 293
+ EK E+++ EK+ ++ + Q+ ++RQ E++Q + +++
Sbjct: 674 --QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 40.4 bits (93), Expect = 0.003
Identities = 53/267 (19%), Positives = 121/267 (45%), Gaps = 10/267 (3%)
Query: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 122
D+ + EKN +L+ ++Q ++ ++ +Q +++ KL+R L +Q++Q +
Sbjct: 277 DEELKEKNA-KLQEKLQLVESEKSEIQLNVKELKRKLER-AKLLLPQQQLQAEADHLGKE 334
Query: 123 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 182
QS +A + E + N + + + K+QE + + Q E + + +
Sbjct: 335 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ----EEKIREQEEK 390
Query: 183 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 242
+ ++R+E+ + +KE ++ + + E + + + E E + EL +
Sbjct: 391 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 450
Query: 243 QAERE-KAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQEL 301
+ RE + E+E +EK + + Q+ K+R+ E+++ + + ++ I E
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE- 509
Query: 302 KEKIAYLE--AENLEMHDRMEHLIEKQ 326
+EKI E E EM + E + E++
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQE 536
>gi|116812628 coiled-coil domain containing 67 [Homo sapiens]
Length = 604
Score = 60.5 bits (145), Expect = 2e-09
Identities = 67/304 (22%), Positives = 130/304 (42%), Gaps = 39/304 (12%)
Query: 47 DGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDS 106
D E + + +L + + + NQ + + Q Q N ++ ED SS++ R + D
Sbjct: 154 DKQEILYQTHLISLDAQQKLLSEKCNQFQKQAQSYQTQLNGKKQCLEDSSSEIPRLICDP 213
Query: 107 LHRQEI----QVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAK 162
EI + ++EK + + +NE S R +QD KL +
Sbjct: 214 DPNCEINERDEFIIEK-----------------LKSAVNEIALS-RNKLQDENQKLLQEL 255
Query: 163 RQHQSDCVAFEVTLSRYQREAEQSNVAL---QREEDRVEQKEAEVGELQRRLLGMETEHQ 219
+ +Q C A E LS + E + + L + E ++ ++ ++GE Q
Sbjct: 256 KMYQRQCQAMEAGLSEVKSELQSRDDLLRIIEMERLQLHRELLKIGECQNAQGNKTRLES 315
Query: 220 ALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQ 279
+ L ++E E ++EL S D EKE+ +R ++ +++ S+Q ++R
Sbjct: 316 SYLPSIKEPERKIKELFSVMQD-------QPNHEKELNKIRSQLQQVEEYHNSEQERMRN 368
Query: 280 MIEQLQNSKAVIQSKDATIQELKEKIAYLEAE-NLEMHDRMEHLIEKQISHGNFSTQARA 338
I L + K+ TI + +K A LE + +E+ + + L ++++S +
Sbjct: 369 EISDLTEE---LHQKEITIATVTKKAALLEKQLKMELEIKEKMLAKQKVSDMKYKA---V 422
Query: 339 KTEN 342
+TEN
Sbjct: 423 RTEN 426
Score = 34.7 bits (78), Expect = 0.14
Identities = 69/301 (22%), Positives = 124/301 (41%), Gaps = 51/301 (16%)
Query: 61 SGDKMIHEKNINQLKSEV----QYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVL 116
S KM E+ + L++ + Q + A+ CL + +++ L R DSL + + +
Sbjct: 30 SNKKMDWERKMRALETRLDLRDQELANAQTCLDQKGQEVG--LLRQKLDSLEKCNLAMT- 86
Query: 117 EKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTL 176
+ G QS A +S + + E LR Q K+ + H + + FE L
Sbjct: 87 QNYEGQLQSLKAQFSK-------LTNNFEKLRLH-QMKQNKVPRKELPHLKEEIPFE--L 136
Query: 177 SRYQREAEQSNVALQREEDRVE---QKEAEVGELQRRLLG-----METEHQALLAKVREG 228
S ++ E+ A RE D+ E Q + Q++LL + + Q+ ++
Sbjct: 137 SNLNQKLEEFR-AKSREWDKQEILYQTHLISLDAQQKLLSEKCNQFQKQAQSYQTQLNGK 195
Query: 229 EVALEELRSN--------NADCQAEREKAATLEK------EVAGLREKIHH----LDDML 270
+ LE+ S + +C+ +EK E+A R K+ L L
Sbjct: 196 KQCLEDSSSEIPRLICDPDPNCEINERDEFIIEKLKSAVNEIALSRNKLQDENQKLLQEL 255
Query: 271 KSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHG 330
K QR+ + M L K+ +QS+D + + +E E L++H + + E Q + G
Sbjct: 256 KMYQRQCQAMEAGLSEVKSELQSRD-------DLLRIIEMERLQLHRELLKIGECQNAQG 308
Query: 331 N 331
N
Sbjct: 309 N 309
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 60.1 bits (144), Expect = 3e-09
Identities = 43/169 (25%), Positives = 85/169 (50%), Gaps = 6/169 (3%)
Query: 159 QEAKRQHQSDCVAFEVTLSRYQREA--EQSNVALQREEDRVEQKEAEVGELQRRLLGMET 216
+E KRQ Q D + + R Q E Q ++EE R EQ+E ++ + + ++ E
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE-KMWKQEEKIREQEE 619
Query: 217 EHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRK 276
+ Q K+RE E E++R Q + EK E+++ EK+ ++ + Q+ K
Sbjct: 620 KIQEQEEKIREQE---EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK 676
Query: 277 VRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 325
+R+ ++++ + I+ ++ +QE +EK+ E + E ++M+ EK
Sbjct: 677 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Score = 48.9 bits (115), Expect = 7e-06
Identities = 72/371 (19%), Positives = 143/371 (38%), Gaps = 61/371 (16%)
Query: 10 LVDVHPEDQAAAGRK------------TYAMVSSHSAGHSLASELVESHDGHEEIIKVYL 57
L D HP+ + G T ++ HS E SH H+E ++ L
Sbjct: 67 LTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQ-HQEALRREL 125
Query: 58 KGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLE 117
+ + I +L+ + Y Q A L+ D+ S+L + +
Sbjct: 126 EAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSW-------------K 172
Query: 118 KPNGFSQSPTALYSSPPEVDTCINE--------DVESLRKTVQD-----LLAKLQEAKRQ 164
Q+ +A+ + + D I E +E R T+ D AKLQE +
Sbjct: 173 FAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQL 232
Query: 165 HQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAK 224
+S+ ++ + +R+ E++ + L ++ Q +AE L + L + + QA +
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQ-----QLQAEADHLGKELQSVSAKLQA---Q 284
Query: 225 VREGEV--------------ALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDML 270
V E E+ E+++ Q + EK E+++ EK+ ++M+
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
Query: 271 KSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHG 330
++ K+R+ E + + ++ ++ + E +EK+ E E +++ L EK
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 331 NFSTQARAKTE 341
Q + E
Sbjct: 405 KIREQEEKRQE 415
Score = 48.9 bits (115), Expect = 7e-06
Identities = 37/168 (22%), Positives = 81/168 (48%), Gaps = 7/168 (4%)
Query: 159 QEAKRQHQSDCVAFEVTLS------RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLL 212
+E KRQ Q + E + R + + + ++++E++V ++E ++ E + ++
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 213 GMETEHQALLAKVREGE-VALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLK 271
E + K+RE E + EE + + + E EK E ++ EKI ++ +
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Query: 272 SQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRM 319
Q+ K+R+ E+ Q + + ++ I+E +EKI E + E +++
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Score = 48.9 bits (115), Expect = 7e-06
Identities = 32/162 (19%), Positives = 76/162 (46%), Gaps = 9/162 (5%)
Query: 159 QEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEH 218
QE KRQ Q E + + + + + +Q +E+++ ++E ++ E + E +
Sbjct: 596 QEEKRQEQ------EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 219 QALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVR 278
K+ E E E+++ + EK EK++ EKI ++M++ Q+ K+
Sbjct: 650 GEQEEKMCEQE---EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706
Query: 279 QMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRME 320
+ E++ + +Q ++ ++ +EK+ E + ++M+
Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 46.6 bits (109), Expect = 4e-05
Identities = 47/268 (17%), Positives = 126/268 (47%), Gaps = 20/268 (7%)
Query: 66 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVVLEKPNGFS 123
++++ ++ + + IQE +Q+ E I + + R + + RQE +++ EK
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE-EMMWEKEEKMR 352
Query: 124 QSPTALYSSPPEV---DTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQ 180
+ ++ ++ + + E E +R+ ++++ + +E R+ + E + +
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ-EEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Query: 181 REAEQSNVALQREEDRVEQKEA-------EVGELQRRLLGMETEHQALLAKVREGEVALE 233
+ E+ + RE+++ +++EA ++ E + ++ E + K+ E E E
Sbjct: 412 KRQEEEKI---REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
Query: 234 ELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS 293
E + + +E+ ++E+ +EK+H ++ ++ Q+ KV + E+++ + I+
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 294 KDATIQELKEKIAYLE---AENLEMHDR 318
++ + +EKI E E +MH++
Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQ 556
Score = 45.1 bits (105), Expect = 1e-04
Identities = 53/285 (18%), Positives = 127/285 (44%), Gaps = 24/285 (8%)
Query: 58 KGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVV 115
K R ++M+ EK +++ + + + E +++ E + K + R L + +H QE ++
Sbjct: 350 KMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIR 407
Query: 116 LEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVT 175
++ + E + + E +R+ Q+ + QE K Q + + +
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE--QEEKIREQEKKMWRQEEKIHEQEK 465
Query: 176 LSRYQREAEQSNVALQ-----------REEDRVEQKEAEVGELQRRLLGMETEHQALLAK 224
+ ++ EQ + Q R+++++ ++E ++ + + ++ E + + K
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK 525
Query: 225 VREGEVAL----EELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQM 280
+RE E + E++R + RE+ E+E EK +D + Q+ K+R+
Sbjct: 526 IREQEEKMWRQEEKIREQE---EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 281 IEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 325
E++ + I+ ++ QE +EK+ E + E ++++ EK
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
Score = 38.5 bits (88), Expect = 0.010
Identities = 28/141 (19%), Positives = 67/141 (47%), Gaps = 4/141 (2%)
Query: 145 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 204
E +R+ + + + ++ + Q + E+T + ++ EQ ++EE EQ+E +
Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET-M 670
Query: 205 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 264
+ ++ E + + K+RE E ++E + + EK E+++ EK+
Sbjct: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE---QEEKMCEQEEKMQEQEEKMR 727
Query: 265 HLDDMLKSQQRKVRQMIEQLQ 285
++ + Q+ ++RQ E++Q
Sbjct: 728 RQEEKMWEQEVRLRQQEEKMQ 748
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 58.9 bits (141), Expect = 7e-09
Identities = 70/297 (23%), Positives = 125/297 (42%), Gaps = 37/297 (12%)
Query: 41 ELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD 100
EL D E +I +G+ E QL+ EV+ + LQ R D +
Sbjct: 1286 ELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLRE 1345
Query: 101 RNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCIN-EDVESLRKTVQDLLAKLQ 159
+ ++ + E+Q VL K N S A + + E D E++E +K + L + +
Sbjct: 1346 QYEEETEAKAELQRVLSKAN----SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAE 1401
Query: 160 EAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQ 219
EA + C + E T R Q E E V VE+ A L ++ +
Sbjct: 1402 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVD-------VERSNAAAAALDKK----QRNFD 1450
Query: 220 ALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLR----EKIHHLDDML---KS 272
+LA+ ++ + + ++ ++ +++A +L E+ L+ E + HL+ K+
Sbjct: 1451 KILAEWKQ------KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKN 1504
Query: 273 QQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISH 329
Q ++ + EQL +S TI EL++ LEAE +E+ +E E + H
Sbjct: 1505 LQEEISDLTEQLGSS-------GKTIHELEKVRKQLEAEKMELQSALEE-AEASLEH 1553
Score = 48.9 bits (115), Expect = 7e-06
Identities = 57/263 (21%), Positives = 120/263 (45%), Gaps = 37/263 (14%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPN--GFSQS 125
EK + +K E ++EA + R+++ K+ L + Q +QV E+ N +
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ-LQVQAEQDNLADAEER 904
Query: 126 PTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAF-------EVTLSR 178
L + +++ + E E L +++ A+L KR+ + +C E+TL++
Sbjct: 905 CDQLIKNKIQLEAKVKEMNERLEDE-EEMNAELTAKKRKLEDECSELKRDIDDLELTLAK 963
Query: 179 YQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSN 238
++E + E +V L + G++ ++AK+ + + AL+E
Sbjct: 964 VEKEKHAT--------------ENKVKNLTEEMAGLD----EIIAKLTKEKKALQEAHQQ 1005
Query: 239 NA-DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDAT 297
D QAE +K TL K L +++ L+ L+ Q++KVR +E+ + + +
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLE-QEKKVRMDLERAK------RKLEGD 1058
Query: 298 IQELKEKIAYLEAENLEMHDRME 320
++ +E I LE + ++ +R++
Sbjct: 1059 LKLTQESIMDLENDKQQLDERLK 1081
Score = 47.0 bits (110), Expect = 3e-05
Identities = 67/346 (19%), Positives = 155/346 (44%), Gaps = 54/346 (15%)
Query: 34 AGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLRE 93
A + L E G +EII K + + H++ ++ L++E ++ N L K +
Sbjct: 970 ATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE----EDKVNTLTKAKV 1025
Query: 94 DISSKLDRNLGDSLHRQEIQVVLEKPNG--------FSQSPTALYSSPPEVD-------- 137
+ ++D G +++++ LE+ +S L + ++D
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 138 --TCINEDVE-------SLRKTVQDLLAKLQEAKRQHQSDCVA---FEVTLSRYQREAEQ 185
+N +E L+K +++L A+++E + + +++ A E S RE E+
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1145
Query: 186 SNVALQR-------EEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEV-ALEELRS 237
+ L+ + + +++EAE +++R L +H+A A +R+ ++ EL
Sbjct: 1146 ISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGE 1205
Query: 238 NNADCQAEREKAATLEKEVAGLREKI----HHLDDMLKSQ---QRKVRQMIEQLQNSKAV 290
+ Q ++K LEKE + + ++ +++ ++K++ ++ R + +Q+ ++
Sbjct: 1206 QIDNLQRVKQK---LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSK 1262
Query: 291 IQSKDATIQELKEKIAYLEAENLEMH---DRMEHLIEKQISHGNFS 333
+ ++ +L + A L+ EN E+ D E LI Q++ G +
Sbjct: 1263 AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALI-SQLTRGKLT 1307
Score = 42.7 bits (99), Expect = 5e-04
Identities = 53/283 (18%), Positives = 116/283 (40%), Gaps = 43/283 (15%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDR---NLGDSLHRQEIQVVLEKPNG--- 121
+ I +L+ E++ + AR ++KLR D+S +L+ L ++ +Q+ + K
Sbjct: 1112 QARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEF 1171
Query: 122 -----------FSQSPTALYSSPPEVDTC--INEDVESLRKTVQDL-------------- 154
TA D+ + E +++L++ Q L
Sbjct: 1172 QKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1231
Query: 155 ---LAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRL 211
+ ++ +AK + C E ++ ++ +AE++ ++ + + + E GEL R+L
Sbjct: 1232 TSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQL 1291
Query: 212 LGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLK 271
E +AL++++ G++ + D + + E+ + +A + H D+L+
Sbjct: 1292 ----DEKEALISQLTRGKLTYTQ---QLEDLKRQLEEEVKAKNALAHALQSARHDCDLLR 1344
Query: 272 SQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLE 314
Q + + +LQ + S+ A + E A E LE
Sbjct: 1345 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1387
Score = 42.7 bits (99), Expect = 5e-04
Identities = 46/286 (16%), Positives = 128/286 (44%), Gaps = 31/286 (10%)
Query: 30 SSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQ 89
SS SL++EL + + +EE ++ + +K + E+ I+ L ++ + + L+
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEE-ISDLTEQLGSSGKTIHELE 1527
Query: 90 KLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRK 149
K+R+ + ++ + E+Q LE+ + I ++E +
Sbjct: 1528 KVRKQLEAE----------KMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE---R 1574
Query: 150 TVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQR 209
+ + ++++AKR H + + +L R ++ ++ E + + E ++ R
Sbjct: 1575 KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANR 1634
Query: 210 RLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDM 269
+ + ++L + +++ ++ L++ N D +E A +E+ +++
Sbjct: 1635 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDL---KENIAIVERR-----------NNL 1680
Query: 270 LKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEM 315
L+++ ++R ++EQ + S+ + + + + E E++ L ++N +
Sbjct: 1681 LQAELEELRAVVEQTERSRKLAEQE---LIETSERVQLLHSQNTSL 1723
Score = 41.2 bits (95), Expect = 0.001
Identities = 60/320 (18%), Positives = 125/320 (39%), Gaps = 63/320 (19%)
Query: 67 HEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--------------------RNLGDS 106
H ++ +L ++ +Q + L+K + + +LD R L D
Sbjct: 1196 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 1255
Query: 107 L--HRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINED---VESLRKTVQDLLAKLQEA 161
+ HR + + N + L + E+ ++E + L + +L++
Sbjct: 1256 MNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDL 1315
Query: 162 KRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQK----------EAEVGELQ--- 208
KRQ + + A Q ++ ++ E+ E K +EV + +
Sbjct: 1316 KRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY 1375
Query: 209 -----RRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEV------- 256
+R +E + L +++E E A+E + NA C + + L+ E+
Sbjct: 1376 ETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV---NAKCSSLEKTKHRLQNEIEDLMVDV 1432
Query: 257 -------AGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLE 309
A L +K + D +L ++K + +L++S+ +S + +LK AY E
Sbjct: 1433 ERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN--AYEE 1490
Query: 310 A-ENLEMHDRMEHLIEKQIS 328
+ E+LE R ++++IS
Sbjct: 1491 SLEHLETFKRENKNLQEEIS 1510
Score = 40.4 bits (93), Expect = 0.003
Identities = 47/263 (17%), Positives = 108/263 (41%), Gaps = 34/263 (12%)
Query: 72 NQLKSEVQYIQEARNCLQKLREDISSKLDRN-LGDSLHRQEIQVVLEKPNGFSQSPTALY 130
+ LK + ++ N LQ E++ + +++ L QE+ E+ T+L
Sbjct: 1665 DDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLI 1724
Query: 131 SSPPEVDT---------------CINEDVESLRKTVQDLLAKLQEAKRQHQSDCVA---- 171
+ ++D C N + E +K + D +E K++ +
Sbjct: 1725 NQKKKMDADLSQLQTEVEEAVQECRNAE-EKAKKAITDAAMMAEELKKEQDTSAHLERMK 1783
Query: 172 --FEVTLSRYQREAEQSN-VALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREG 228
E T+ Q +++ +AL+ + ++++ EA V EL+ L + + + +R+
Sbjct: 1784 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKS 1843
Query: 229 EVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSK 288
E ++EL Q E ++ K + L++ + L +K+ +R+ + EQ +
Sbjct: 1844 ERRIKEL-----TYQTEEDR-----KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNL 1893
Query: 289 AVIQSKDATIQELKEKIAYLEAE 311
+ + + E +E+ E++
Sbjct: 1894 SKFRKVQHELDEAEERADIAESQ 1916
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 58.9 bits (141), Expect = 7e-09
Identities = 45/204 (22%), Positives = 101/204 (49%), Gaps = 19/204 (9%)
Query: 120 NGFSQSPTALYSSPPEVDTCINE--DVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLS 177
N SP A +S+ E+DT NE D++ + V+ L + ++ +Q S+ +
Sbjct: 319 NIIGSSPVADFSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSE-------VQ 371
Query: 178 RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRS 237
Q E ++ N LQ+ + + +Q + + EL + +E + + + K E + L+
Sbjct: 372 DLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLK- 430
Query: 238 NNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDAT 297
A+ ++ + +T E+E+A RE++ L Q++ ++ E +++ KA ++
Sbjct: 431 --AELTSQESQISTYEEELAKAREELSRL-------QQETAELEESVESGKAQLEPLQQH 481
Query: 298 IQELKEKIAYLEAENLEMHDRMEH 321
+Q+ +++I+ ++ + +EM D H
Sbjct: 482 LQDSQQEISSMQMKLMEMKDLENH 505
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 58.5 bits (140), Expect = 9e-09
Identities = 69/315 (21%), Positives = 139/315 (44%), Gaps = 49/315 (15%)
Query: 55 VYLKGRSGDKMIHEKNI-NQLKSEVQYIQEARNCLQKLREDISSKLDRN----LGDSLHR 109
+ +K R ++ KN+ N L++E+ + + L+ E+ KL R +
Sbjct: 415 IQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKE 474
Query: 110 QEIQVVLE---KPNGFSQSPTA--------LYSSPPEVDTCIN------EDVESLRKTVQ 152
E++ +E K N +S + L + + C+N E++++ + +
Sbjct: 475 NELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQE 534
Query: 153 DLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLL 212
+L LQE Q ++ ++ L+ E ++ +D ++++E + +L +L
Sbjct: 535 TMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDC-----SQDLLKKREHHIEQLNDKLS 589
Query: 213 GMETEHQALLAKVREGEVALEELRSNNA--DC-QAEREKAAT-LEKEVAGLREKIHHLDD 268
E E +ALL+ + + EEL+ C ++E EK T +E E L+ KI+HL+
Sbjct: 590 KTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLET 649
Query: 269 MLKSQQRKVRQMIE--------------QLQNSKAVIQSKDATIQELKEKIAYLEAENLE 314
LK+QQ K + E +++N V+ SK ++ +K+AY+E +
Sbjct: 650 CLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVE--TQKLAYMELQQKA 707
Query: 315 MHDRMEHLIEKQISH 329
+H +K+I +
Sbjct: 708 EFSDQKH--QKEIEN 720
Score = 52.0 bits (123), Expect = 8e-07
Identities = 57/268 (21%), Positives = 116/268 (43%), Gaps = 24/268 (8%)
Query: 72 NQLKSEVQYIQEARNCLQKLREDISSK---LDRNLGDSLHRQEI-QVVLEKPNGFSQSPT 127
NQL+ E+ + + L +L E + K L+ + + LH ++ + +++ Q+ +
Sbjct: 1961 NQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLS 2020
Query: 128 ALYSSPPEVDTCINEDVESLRKTVQDL----------LAKLQEAKRQHQSDCVAFEVTLS 177
+ S + T + E ++SL K Q L +A+L + K + + + LS
Sbjct: 2021 SDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS 2080
Query: 178 RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRS 237
+ + E+ NV+ E VE+ GE RL + E L + + V +E
Sbjct: 2081 --ESDYEKLNVSKALEAALVEK-----GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEK 2133
Query: 238 NNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDAT 297
EK E+E L++K+ +L+ L+ + +I +NSKA +++
Sbjct: 2134 KQLHIA---EKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQ 2190
Query: 298 IQELKEKIAYLEAENLEMHDRMEHLIEK 325
I+E+ + E + + + E+L ++
Sbjct: 2191 IEEMARSLKVFELDLVTLRSEKENLTKQ 2218
Score = 48.5 bits (114), Expect = 9e-06
Identities = 56/279 (20%), Positives = 116/279 (41%), Gaps = 37/279 (13%)
Query: 72 NQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKP---NGFSQSPTA 128
N++ + + Q+ + LR+ + SK + + H++ + ++P + F+
Sbjct: 744 NEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGE 803
Query: 129 LYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNV 188
S P E C E +S + + A Q++ D + F + +Q N
Sbjct: 804 QGSMPSERSECRLEADQSPKNS----------AILQNRVDSLEFSL------ESQKQMNS 847
Query: 189 ALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEE-------------- 234
LQ++ + + Q + GE++ L+ E HQ+ +A+ + L+E
Sbjct: 848 DLQKQCEELVQIK---GEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLS 904
Query: 235 -LRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS 293
L + + Q +K T + E+ L++ H L+D LK Q + + + ++I
Sbjct: 905 ALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISL 964
Query: 294 KDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNF 332
I+EL ++ L+ N ++ +LI+K S N+
Sbjct: 965 NKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANY 1003
Score = 47.8 bits (112), Expect = 2e-05
Identities = 65/307 (21%), Positives = 139/307 (45%), Gaps = 45/307 (14%)
Query: 28 MVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNC 87
+V+ S +L ++ E E+ K+ +S ++ EK ++E+Q +E++
Sbjct: 2205 LVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKS---LLEEKE----QAEIQIKEESKTA 2257
Query: 88 LQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESL 147
++ L+ + +L+ + QEI E+ S P P E + + +E L
Sbjct: 2258 VEMLQNQLK-ELNEAVAALCGDQEIMKATEQ----SLDP------PIEEEHQLRNSIEKL 2306
Query: 148 RKTVQ----DLLAKLQEAKR-QHQSDCVAFEVTLSRYQREAE-----QSNVALQREEDR- 196
R ++ L LQ+ K +H +D + V +RE E Q + AL+ E +
Sbjct: 2307 RARLEADEKKQLCVLQQLKESEHHADLLKGRV--ENLERELEIARTNQEHAALEAENSKG 2364
Query: 197 -VEQKEAEVGELQRRLLGME-------TEHQALLAKVREGEVALEELRSNNADCQAEREK 248
VE +A++ + + L G+E +E + L ++++ + + EL N+ + ++
Sbjct: 2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQE 2424
Query: 249 AATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYL 308
E+E ++EK +ML++Q +++ + + L N + ++K+ Q L ++ L
Sbjct: 2425 K---EQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKE---QNLSSQVECL 2478
Query: 309 EAENLEM 315
E E ++
Sbjct: 2479 ELEKAQL 2485
Score = 44.7 bits (104), Expect = 1e-04
Identities = 63/294 (21%), Positives = 128/294 (43%), Gaps = 35/294 (11%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQE-IQVVLEKPNGFSQSP 126
E+ I L+S+ +Q+ LQ +++ ++L+ D + E + + K +
Sbjct: 2566 EQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREM 2625
Query: 127 TALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQS 186
+ E+ ++ + L +Q LL +++ +K Q + E+TL E ++S
Sbjct: 2626 HEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLK------ELTLEN--SELKKS 2677
Query: 187 NVALQREEDRVEQK-EAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAE 245
+ +++ E K E+ E Q RL E +HQALL L+ + + Q
Sbjct: 2678 LDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALL---------LDTNKQYEVEIQTY 2728
Query: 246 REKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI 305
REK + E+ ++ + +I D+LKS + ++ L+ + +++ T + + +
Sbjct: 2729 REKLTSKEECLSSQKLEI----DLLKSSKEELN---NSLKATTQILEELKKTKMDNLKYV 2781
Query: 306 AYLEAENLEMHDRMEHLI--------EKQISHGNFS-TQARAKTENPGSIRISK 350
L+ EN +M+ LI EK+I S QA + + G++ +K
Sbjct: 2782 NQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTK 2835
Score = 44.7 bits (104), Expect = 1e-04
Identities = 72/337 (21%), Positives = 149/337 (44%), Gaps = 56/337 (16%)
Query: 63 DKMIHEKNINQLKS-EVQYIQEARNCLQK---LREDISSKLDRNLGDSLHRQEIQVVLEK 118
DKM + +N++ + E + +E QK L+E++S + +R G E+Q++LE+
Sbjct: 2603 DKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAG------ELQLLLEE 2656
Query: 119 PNGFSQSPTALYSSPPEVDT---CINED-VES---LRKTVQDLLAKLQEAKRQHQSDCVA 171
L E+ C+++D VE +R+ + + +L EA+++HQ+ +
Sbjct: 2657 IKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLD 2716
Query: 172 FEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVA 231
T +Y+ E + L +E+ + ++ E+ L+ + + L ++
Sbjct: 2717 ---TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLK-------SSKEELNNSLKATTQI 2766
Query: 232 LEELRSNNAD-------CQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQL 284
LEEL+ D + E E+A K + +++ ++L+ + ++ Q ++
Sbjct: 2767 LEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQL-QAAQEK 2825
Query: 285 QNSKAVIQSK-DATIQELKEKIAYLEAENLE-------------MHDRME---HLIEKQI 327
Q + V+ +K D E+KE LE + E H+++E ++E Q+
Sbjct: 2826 QKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQV 2885
Query: 328 SHGNFSTQARAKTENPGSIRISKPPSPKPMPVIRVVE 364
+H ++K ++ GS + P P P P+ V E
Sbjct: 2886 AH---LCSQQSKQDSRGSPLLG-PVVPGPSPIPSVTE 2918
Score = 33.5 bits (75), Expect = 0.31
Identities = 59/319 (18%), Positives = 129/319 (40%), Gaps = 42/319 (13%)
Query: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 122
D +H + + QL ++++ E + +L+++ S ++ S QE+ +E G
Sbjct: 1808 DSKLHLQEV-QLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGL 1866
Query: 123 SQSPTALYSSPPEVD-----TCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLS 177
+ D +N+ + V++ L++++ K + + + E L
Sbjct: 1867 NSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLE 1926
Query: 178 RYQREA---EQSNVALQRE----EDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEV 230
Q E E+ N Q+ E+ + +E +L+ L M + AL + +
Sbjct: 1927 VVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKE 1986
Query: 231 ALEELRSNNADC-----------QAEREKAATLEKEVAGLREKIHHLDDMLKSQQR---- 275
+EL S+ ++C + + E TL +V+ L + HL + L+S ++
Sbjct: 1987 KTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQA 2046
Query: 276 ------KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRME-HLIEKQIS 328
++ I QL K ++ + + L+ +++ + E L + +E L+EK
Sbjct: 2047 LSLTKCELENQIAQLNKEKELLVKES---ESLQARLSESDYEKLNVSKALEAALVEK--- 2100
Query: 329 HGNFSTQARAKTENPGSIR 347
G F+ + + E +R
Sbjct: 2101 -GEFALRLSSTQEEVHQLR 2118
Score = 30.4 bits (67), Expect = 2.6
Identities = 63/328 (19%), Positives = 128/328 (39%), Gaps = 67/328 (20%)
Query: 51 EIIKVYLKGRSGDKMIHEKN-INQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR 109
E ++ L+ D + K+ LK E+ ++E +N +QK D+ + ++ + +
Sbjct: 1104 ETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTK 1163
Query: 110 QEIQVVLEKPNGFS----QSPTALYSSPPEVDTCINE--------DVESLRKTVQDLLAK 157
E Q + +P S +S + P++D + E + L +++ K
Sbjct: 1164 HECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELK 1223
Query: 158 LQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLG---- 213
LQE++++ +C+ E L + + E SN+ + ++ K+ E+ ++ + G
Sbjct: 1224 LQESEKE--KECLQHE--LQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHEL 1279
Query: 214 ---------METEHQALLAKVREGEVALE-----------ELRSNNADCQAEREKAATLE 253
++ Q + K+ E E E EL + ++C K A
Sbjct: 1280 STSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMA--- 1336
Query: 254 KEVAGLREKIHHLDD-------------------MLKSQQRKVRQMIEQLQNSKAVIQSK 294
+EV L ++ L+D ++Q V NS +
Sbjct: 1337 EEVGKLLNEVKILNDDSGLLHGELVEDIPGGEFGEQPNEQHPVSLAPLDESNSYEHLTLS 1396
Query: 295 DATIQ----ELKEKIAYLEAENLEMHDR 318
D +Q EL+EK L++E+ +HD+
Sbjct: 1397 DKEVQMHFAELQEKFLSLQSEHKILHDQ 1424
Score = 28.5 bits (62), Expect = 9.9
Identities = 15/68 (22%), Positives = 32/68 (47%)
Query: 253 EKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAEN 312
+++V L ++ LD L Q+ ++ IE + ++ +L EK+ Y ++
Sbjct: 1794 DRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDH 1853
Query: 313 LEMHDRME 320
E+ R+E
Sbjct: 1854 QELLQRVE 1861
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 57.8 bits (138), Expect = 2e-08
Identities = 57/296 (19%), Positives = 130/296 (43%), Gaps = 16/296 (5%)
Query: 66 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVVLEKPNGFS 123
++++ ++ + + IQE +Q+ E I + + R + + RQE +++ EK
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE-EMMWEKEEKMR 352
Query: 124 QSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREA 183
+ ++ ++ + E + + +++L K+ E ++ + + E R Q +
Sbjct: 353 RQEEMMWEKEEKMRR-LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 411
Query: 184 EQSNVALQREEDRVEQKEAEVGELQRRLLGMETE-HQALLAKVREGEV--------ALEE 234
++ + R+E+++ ++E ++ E ++++ E + H+ K+RE E EE
Sbjct: 412 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ--EKIREEEKRQEQEEMWRQEE 469
Query: 235 LRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSK 294
+ ++EK EK + EK+ ++ + Q+ K+R+ E++ + I+ +
Sbjct: 470 KIREQEEIWRQKEKMHEQEK-IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ 528
Query: 295 DATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSIRISK 350
+ I+E +EKI E E ++M EK Q E IR K
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584
Score = 56.6 bits (135), Expect = 3e-08
Identities = 66/310 (21%), Positives = 138/310 (44%), Gaps = 36/310 (11%)
Query: 50 EEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSL 107
E+I + K R ++M+ EK +++ + + + E +++L E + K + R L + +
Sbjct: 328 EKIREQEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM 386
Query: 108 HRQE-IQVVLEKPNGFSQSPTALYSSPPEV-----DTCINEDVESLRKTVQDLLAK---- 157
H QE I+ EK + E + I E E +R+ + + +
Sbjct: 387 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 446
Query: 158 ------LQEAKRQHQSDCVAFEVTLSRYQREA--------EQSNVALQ-----REEDRVE 198
+E KRQ Q + E + R Q E EQ + Q R+E+++
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKI-REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH 505
Query: 199 QKEAEVGELQRRLLGMETEHQALLAKVREGEVAL---EELRSNNADCQAEREKAATLEKE 255
+E ++ E + ++ E + + K+RE E + EE+ + E+E+ +++
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565
Query: 256 VAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEM 315
+ EKI ++ ++ Q+ K+R+ E++ + I+ ++ +QE +EK+ E + E
Sbjct: 566 MRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 625
Query: 316 HDRMEHLIEK 325
++M+ EK
Sbjct: 626 EEKMQEQEEK 635
Score = 55.8 bits (133), Expect = 6e-08
Identities = 72/357 (20%), Positives = 140/357 (39%), Gaps = 47/357 (13%)
Query: 10 LVDVHPEDQAAAGRK------------TYAMVSSHSAGHSLASELVESHDGHEEIIKVYL 57
L D HP+ + G T ++ HS E SH H+E ++ L
Sbjct: 67 LTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQ-HQEALRREL 125
Query: 58 KGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLE 117
+ + I +L+ + Y Q A L+ D+ S+L + +
Sbjct: 126 EAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSW-------------K 172
Query: 118 KPNGFSQSPTALYSSPPEVDTCINE--------DVESLRKTVQD-----LLAKLQEAKRQ 164
Q+ +A+ + + D I E +E R T+ D AKLQE +
Sbjct: 173 FAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQL 232
Query: 165 HQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAK 224
+S+ ++ + +R+ E++ + L ++ Q +AE L + L + + QA +
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQ-----QLQAEADHLGKELQSVSAKLQA---Q 284
Query: 225 VREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQL 284
V E E+ + + EK E+++ EKI ++ ++ Q+ K+R+ E +
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
Query: 285 QNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTE 341
+ ++ ++ + E +EK+ LE E +++ L EK Q + E
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 401
Score = 50.4 bits (119), Expect = 2e-06
Identities = 39/183 (21%), Positives = 88/183 (48%), Gaps = 11/183 (6%)
Query: 145 ESLRKTVQDLLAKLQEAKRQHQSDCVAF-EVTLSRYQREAEQSNVALQREEDRVEQKEAE 203
E +RK Q+ QE K Q + + E + R + + + ++ +E+++ ++E E
Sbjct: 488 EKIRK--QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE-E 544
Query: 204 VGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKI 263
+ + Q +G + E K+R E E++R + ++EK E+++ EKI
Sbjct: 545 MMQEQEEKMGEQEEKMQEQEKMRRQE---EKIREQEEKIREQKEKIREQEEKIWEQEEKI 601
Query: 264 HHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI----AYLEAENLEMHDRM 319
++M++ Q+ K+ + E++ + +Q ++ ++ +EK+ L + +M +
Sbjct: 602 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Query: 320 EHL 322
EHL
Sbjct: 662 EHL 664
Score = 48.9 bits (115), Expect = 7e-06
Identities = 32/174 (18%), Positives = 79/174 (45%), Gaps = 3/174 (1%)
Query: 159 QEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEH 218
QE R+ + E + + + + + R+E+++ ++E ++ E + ++ E
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM 546
Query: 219 QALLAKVREGEVALEE---LRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR 275
Q K+ E E ++E +R + + EK ++++ EKI ++ ++ Q+
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606
Query: 276 KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISH 329
+++ E++ + + ++ +QE +EK+ E + E R+ EK H
Sbjct: 607 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/135 (20%), Positives = 66/135 (48%), Gaps = 3/135 (2%)
Query: 159 QEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEH 218
QE K + Q + + + Q E Q ++R+E+++ ++E ++ E + ++ E +
Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI 594
Query: 219 QALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVR 278
K+RE E ++E + + EK E+++ EK+ ++ + Q+ ++R
Sbjct: 595 WEQEEKIREQEEMMQEQEEKMWE---QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 651
Query: 279 QMIEQLQNSKAVIQS 293
Q E++Q + +++
Sbjct: 652 QQEEKMQEHQEHLEA 666
Score = 42.7 bits (99), Expect = 5e-04
Identities = 54/267 (20%), Positives = 122/267 (45%), Gaps = 10/267 (3%)
Query: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 122
D+ + EKN +L+ ++Q ++ ++ +Q +++ KL+R L +Q++Q +
Sbjct: 216 DEELKEKNA-KLQEKLQLVESEKSEIQLNVKELKRKLER-AKLLLPQQQLQAEADHLGKE 273
Query: 123 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 182
QS +A + E + N + + + K+QE + + Q E + + +
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ----EEKIREQEEK 329
Query: 183 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 242
+ ++R+E+ + +KE ++ + + E + + L + E E + EL +
Sbjct: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ 389
Query: 243 QAERE-KAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQEL 301
+ RE + E+E +EK + + Q+ K+R+ E+++ + + ++ I E
Sbjct: 390 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE- 448
Query: 302 KEKIAYLE--AENLEMHDRMEHLIEKQ 326
+EKI E E EM + E + E++
Sbjct: 449 QEKIREEEKRQEQEEMWRQEEKIREQE 475
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 57.8 bits (138), Expect = 2e-08
Identities = 63/321 (19%), Positives = 143/321 (44%), Gaps = 36/321 (11%)
Query: 37 SLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLK--------SEVQYIQEARNCL 88
SL S+L ++ + ++I ++ H++ + +LK +E E + +
Sbjct: 558 SLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQI 617
Query: 89 QKLREDISSKLD--RNLGDS---LHRQEIQ--------VVLEKPNGFSQSPTALYSSPP- 134
+K+R D +++ +N DS H +E++ V+ EK N + L +
Sbjct: 618 EKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQ 677
Query: 135 ---EVDTCIN--EDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVT------LSRYQREA 183
E++ +N ++ E K ++ L AK E + + + T L ++ +
Sbjct: 678 HLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKAS 737
Query: 184 EQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQ 243
+ +++ ++E E ++ L+ ++ ++ +++ E+ L L+ N ++
Sbjct: 738 SEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVS 797
Query: 244 AEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKE 303
+E TLEKE+ L+EK + S QR +++ + +L + + +++L+E
Sbjct: 798 QVKE---TLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRE 854
Query: 304 KIAYLEAENLEMHDRMEHLIE 324
+A +EA+ E +R E LI+
Sbjct: 855 NLADMEAKFREKDEREEQLIK 875
Score = 53.5 bits (127), Expect = 3e-07
Identities = 67/335 (20%), Positives = 143/335 (42%), Gaps = 34/335 (10%)
Query: 10 LVDVHPEDQAAAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEK 69
L D+ + + R+ + + + +A + S D ++ K+ + + + E+
Sbjct: 856 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKM-----NDELRLKER 910
Query: 70 NINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQE------------IQVVLE 117
++ +L+ ++ E + LQK ED++ K +++ ++ + E ++ +E
Sbjct: 911 DVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKME 970
Query: 118 KPNGFSQSPTALYS-SPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTL 176
+ Q A Y + E T E +++L+KT+ D KL+ A+ ++ L
Sbjct: 971 TSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSG----LLQEL 1026
Query: 177 SRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQAL------LAKVREGEV 230
+++A+++ A Q ED ++ E E L +E Q L ++E +
Sbjct: 1027 EELRKQADKAKAA-QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNL 1085
Query: 231 A-LEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKA 289
+EEL + E +K KE+ L++ L + Q + ++ E+L S+
Sbjct: 1086 KNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRD 1145
Query: 290 VIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIE 324
+ S Q+L+E+ + L + LEM R I+
Sbjct: 1146 EVTSH----QKLEEERSVLNNQLLEMKKRESKFIK 1176
Score = 40.4 bits (93), Expect = 0.003
Identities = 59/318 (18%), Positives = 121/318 (38%), Gaps = 62/318 (19%)
Query: 67 HEKNINQLKS-----------EVQYIQEARNCLQKLREDISSKLDRNLGDS-----LHRQ 110
H++ I LK E++ + A L K E + SKL+ ++ L +
Sbjct: 520 HQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKS 579
Query: 111 EIQVVLEKPNGFSQSPTALYSSPPEVDTC----INEDVESLRKTVQDLLAKLQEA----K 162
+++ + + +S +T + +E +R Q + LQ +
Sbjct: 580 KLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSER 639
Query: 163 RQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQK-------------EAEVGELQR 209
H + A L + +E E S A++ + D+ E + EAE+ +
Sbjct: 640 AAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKEL 699
Query: 210 RLLGMETEHQ--------ALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLRE 261
+L + Q + L E + L+ LR +++ ++E +K L +++ +
Sbjct: 700 EVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKK---LRQQLEAAEK 756
Query: 262 KIHHLD--------------DMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAY 307
+I HL+ L+ ++ K+ + E L V ++ + +Q LKEK A
Sbjct: 757 QIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAE 816
Query: 308 LEAENLEMHDRMEHLIEK 325
E + + M+ + K
Sbjct: 817 ASEEAVSVQRSMQETVNK 834
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 57.8 bits (138), Expect = 2e-08
Identities = 63/321 (19%), Positives = 143/321 (44%), Gaps = 36/321 (11%)
Query: 37 SLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLK--------SEVQYIQEARNCL 88
SL S+L ++ + ++I ++ H++ + +LK +E E + +
Sbjct: 593 SLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQI 652
Query: 89 QKLREDISSKLD--RNLGDS---LHRQEIQ--------VVLEKPNGFSQSPTALYSSPP- 134
+K+R D +++ +N DS H +E++ V+ EK N + L +
Sbjct: 653 EKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQ 712
Query: 135 ---EVDTCIN--EDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVT------LSRYQREA 183
E++ +N ++ E K ++ L AK E + + + T L ++ +
Sbjct: 713 HLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKAS 772
Query: 184 EQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQ 243
+ +++ ++E E ++ L+ ++ ++ +++ E+ L L+ N ++
Sbjct: 773 SEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVS 832
Query: 244 AEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKE 303
+E TLEKE+ L+EK + S QR +++ + +L + + +++L+E
Sbjct: 833 QVKE---TLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRE 889
Query: 304 KIAYLEAENLEMHDRMEHLIE 324
+A +EA+ E +R E LI+
Sbjct: 890 NLADMEAKFREKDEREEQLIK 910
Score = 53.5 bits (127), Expect = 3e-07
Identities = 67/335 (20%), Positives = 143/335 (42%), Gaps = 34/335 (10%)
Query: 10 LVDVHPEDQAAAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEK 69
L D+ + + R+ + + + +A + S D ++ K+ + + + E+
Sbjct: 891 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKM-----NDELRLKER 945
Query: 70 NINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQE------------IQVVLE 117
++ +L+ ++ E + LQK ED++ K +++ ++ + E ++ +E
Sbjct: 946 DVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKME 1005
Query: 118 KPNGFSQSPTALYS-SPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTL 176
+ Q A Y + E T E +++L+KT+ D KL+ A+ ++ L
Sbjct: 1006 TSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSG----LLQEL 1061
Query: 177 SRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQAL------LAKVREGEV 230
+++A+++ A Q ED ++ E E L +E Q L ++E +
Sbjct: 1062 EELRKQADKAKAA-QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNL 1120
Query: 231 A-LEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKA 289
+EEL + E +K KE+ L++ L + Q + ++ E+L S+
Sbjct: 1121 KNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRD 1180
Query: 290 VIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIE 324
+ S Q+L+E+ + L + LEM R I+
Sbjct: 1181 EVTSH----QKLEEERSVLNNQLLEMKKRESKFIK 1211
Score = 40.4 bits (93), Expect = 0.003
Identities = 59/318 (18%), Positives = 121/318 (38%), Gaps = 62/318 (19%)
Query: 67 HEKNINQLKS-----------EVQYIQEARNCLQKLREDISSKLDRNLGDS-----LHRQ 110
H++ I LK E++ + A L K E + SKL+ ++ L +
Sbjct: 555 HQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKS 614
Query: 111 EIQVVLEKPNGFSQSPTALYSSPPEVDTC----INEDVESLRKTVQDLLAKLQEA----K 162
+++ + + +S +T + +E +R Q + LQ +
Sbjct: 615 KLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSER 674
Query: 163 RQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQK-------------EAEVGELQR 209
H + A L + +E E S A++ + D+ E + EAE+ +
Sbjct: 675 AAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKEL 734
Query: 210 RLLGMETEHQ--------ALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLRE 261
+L + Q + L E + L+ LR +++ ++E +K L +++ +
Sbjct: 735 EVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKK---LRQQLEAAEK 791
Query: 262 KIHHLD--------------DMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAY 307
+I HL+ L+ ++ K+ + E L V ++ + +Q LKEK A
Sbjct: 792 QIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAE 851
Query: 308 LEAENLEMHDRMEHLIEK 325
E + + M+ + K
Sbjct: 852 ASEEAVSVQRSMQETVNK 869
Score = 32.0 bits (71), Expect = 0.90
Identities = 35/151 (23%), Positives = 63/151 (41%), Gaps = 23/151 (15%)
Query: 175 TLSRYQREAEQSNV---ALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVA 231
T SRY R+ + AL+ ++ +EQ AE +L+R + T H V E E
Sbjct: 339 TSSRYARKISGTTALQEALKEKQQHIEQLLAE-RDLERAEVAKATSH------VGEIEQE 391
Query: 232 LEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVI 291
L R + ++ V L K+ L M+++ R+ +++ QL+ K +
Sbjct: 392 LALARDGH-------------DQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKV 438
Query: 292 QSKDATIQELKEKIAYLEAENLEMHDRMEHL 322
+ ++E LE + H R++ L
Sbjct: 439 EDLQFRVEEESITKGDLETQTKLEHARIKEL 469
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 57.8 bits (138), Expect = 2e-08
Identities = 72/325 (22%), Positives = 134/325 (41%), Gaps = 51/325 (15%)
Query: 61 SGDKMIHEKNINQLKSEVQYIQEARNCL----QKLREDISSKLDRNLGDSLHRQEIQVVL 116
S K + I +LK +++ +A+N L Q R D ++ + + E+Q L
Sbjct: 1305 SRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL 1364
Query: 117 EKPNGFSQSPTALYSSPPEVDTC-INEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVT 175
K N S A + + E D E++E +K + L + +E + C + E T
Sbjct: 1365 SKAN----SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKT 1420
Query: 176 LSRYQRE-------AEQSNVAL------QREEDRV--------EQKEAEVGELQRRLLGM 214
R Q E E+SN A QR D+V E+ +AE+ Q+ +
Sbjct: 1421 KQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSL 1480
Query: 215 ETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQ 274
TE + E LE LR N + Q E + L +++A ++IH L+ + K +
Sbjct: 1481 STELFKVKNVYEESLDQLETLRRENKNLQQE---ISDLTEQIAEGGKQIHELEKIKKQVE 1537
Query: 275 RKVRQMIEQLQNSKAVIQSK------------------DATIQELKEKIAYLEAENLEMH 316
++ ++ L+ ++A ++ + D I E E+I L+ + +
Sbjct: 1538 QEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVV 1597
Query: 317 DRMEHLIEKQISHGNFSTQARAKTE 341
+ M+ ++ +I N + + + K E
Sbjct: 1598 ETMQSTLDAEIRSRNDALRVKKKME 1622
Score = 48.5 bits (114), Expect = 9e-06
Identities = 60/274 (21%), Positives = 115/274 (41%), Gaps = 35/274 (12%)
Query: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 122
+K E + L E+ + E L K ++ + + L D +Q +K N
Sbjct: 970 EKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDD------LQAEEDKVNIL 1023
Query: 123 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 182
+++ T L +VD D+E + + L L+ AKR+ + D L Q
Sbjct: 1024 TKAKTKLEQ---QVD-----DLEGSLEQEKKLRMDLERAKRKLEGD-------LKLAQES 1068
Query: 183 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 242
Q+ ++++E+KE E+ L ++ + L K++E + +EEL +
Sbjct: 1069 TMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEEL---GEEI 1125
Query: 243 QAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS-----KDAT 297
+AER A EK+ + L ++ + + L+ +E + +A Q ++AT
Sbjct: 1126 EAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEAT 1185
Query: 298 IQE------LKEKIAYLEAENLEMHDRMEHLIEK 325
+Q L++K A AE E D ++ + +K
Sbjct: 1186 LQHEAMVAALRKKHADSMAELGEQIDNLQRVKQK 1219
Score = 43.5 bits (101), Expect = 3e-04
Identities = 50/253 (19%), Positives = 115/253 (45%), Gaps = 15/253 (5%)
Query: 74 LKSEVQYIQEARNCLQKLREDISSKLDRN-LGDSLHRQEIQVVLEKPNGFSQSPTALYSS 132
LK ++ ++ N LQ E++ + L++ + QE+ E+ T+L ++
Sbjct: 1670 LKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1729
Query: 133 PPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQR 192
+++ DV L+ V++++ + + A+ + + + ++ ++ + ++ L+R
Sbjct: 1730 KKKLEN----DVSQLQSEVEEVIQESRNAEEKAKK-AITDAAMMAEELKKEQDTSAHLER 1784
Query: 193 EEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATL 252
+ +EQ V +LQ RL E + L K + ++ E R + + E E+
Sbjct: 1785 MKKNLEQT---VKDLQHRL----DEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNA 1837
Query: 253 EKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAEN 312
E V GLR+ + + L Q + R+ + +LQ+ +Q+K + + E+ N
Sbjct: 1838 EA-VKGLRKHERRVKE-LTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNAN 1895
Query: 313 LEMHDRMEHLIEK 325
L +++H +E+
Sbjct: 1896 LSKFRKLQHELEE 1908
Score = 42.4 bits (98), Expect = 7e-04
Identities = 47/205 (22%), Positives = 93/205 (45%), Gaps = 24/205 (11%)
Query: 68 EKNINQLKSEVQ-YIQEARNCLQKLREDISS------KLDRNLGDSLHRQEIQVVLEKPN 120
E +++QL+SEV+ IQE+RN +K ++ I+ +L + S H + ++ LE
Sbjct: 1734 ENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE--- 1790
Query: 121 GFSQSPTALYSSPPEVDTCI----NEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTL 176
Q+ L E + + ++ L V++L +++ ++++
Sbjct: 1791 ---QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHE 1847
Query: 177 SR-----YQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVA 231
R YQ E ++ NV R +D V++ +A+V +R+ E + A L+K R+ +
Sbjct: 1848 RRVKELTYQTEEDRKNVL--RLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHE 1905
Query: 232 LEELRSNNADCQAEREKAATLEKEV 256
LEE +++ K +EV
Sbjct: 1906 LEEAEERADIAESQVNKLRVKSREV 1930
Score = 40.4 bits (93), Expect = 0.003
Identities = 61/289 (21%), Positives = 121/289 (41%), Gaps = 39/289 (13%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQ-EIQVVLEKPNGFSQSP 126
EK + +K E Q ++ + R+++ K+ L + Q ++Q + +
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERC 908
Query: 127 TALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAF-------EVTLSRY 179
L + +++ I E E + +++ A+L KR+ + +C E+TL++
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEE-EEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 967
Query: 180 QREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNN 239
++E + E +V L + G++ +AK+ + + AL+E
Sbjct: 968 EKEKHAT--------------ENKVKNLTEEMAGLD----ETIAKLSKEKKALQETHQQT 1009
Query: 240 A-DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQ--------LQNSKAV 290
D QAE +K L K L +++ L+ L+ Q++K+R +E+ L+ ++
Sbjct: 1010 LDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLE-QEKKLRMDLERAKRKLEGDLKLAQES 1068
Query: 291 IQSKDATIQELKEKIAYLEAE--NLEMHDRMEHLIEKQISHGNFSTQAR 337
+ Q+L EK+ E E NL E +E Q+ QAR
Sbjct: 1069 TMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQAR 1117
Score = 39.7 bits (91), Expect = 0.004
Identities = 56/287 (19%), Positives = 126/287 (43%), Gaps = 27/287 (9%)
Query: 50 EEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR 109
+++ ++ K ++I++ + + + + + +R +K + + S+L R+ S +
Sbjct: 1257 DQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEK--DALVSQLSRSKQASTQQ 1314
Query: 110 -QEIQVVLEKPNGFSQSPT-ALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQS 167
+E++ LE+ + AL SS + D + E Q+ A+LQ A + S
Sbjct: 1315 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEE-----QEGKAELQRALSKANS 1369
Query: 168 DCVAFEVTLSRYQREAEQSNVALQREE----DRVEQKEAEVGELQRRLLGMETEHQALLA 223
+ + ++Y+ +A Q L+ + R+++ E V + + +E Q L
Sbjct: 1370 EVAQWR---TKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQN 1426
Query: 224 KVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQ 283
+V + + ++ +NA C A +K +K ++ ++K L++ Q++ R + +
Sbjct: 1427 EVED---LMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTE 1483
Query: 284 LQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHG 330
L K V +E +++ L EN + + L E QI+ G
Sbjct: 1484 LFKVKNV-------YEESLDQLETLRRENKNLQQEISDLTE-QIAEG 1522
Score = 37.4 bits (85), Expect = 0.021
Identities = 54/249 (21%), Positives = 107/249 (42%), Gaps = 43/249 (17%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT 127
+ I +L E++ + +R +K R D+S +L+ EI LE+ G + +
Sbjct: 1115 QARIEELGEEIEAERASRAKAEKQRSDLSRELE----------EISERLEEAGGATSAQV 1164
Query: 128 ALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSN 187
L N+ E+ Q L L+EA QH++ A + E +
Sbjct: 1165 EL-----------NKKREA---EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQI 1210
Query: 188 VALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAK-VREGEVALEELRSNNADCQAER 246
LQR + ++E++++E L MET+ + A+ + + + LE++ C++
Sbjct: 1211 DNLQRVKQKLEKEKSE--------LKMETDDLSSNAEAISKAKGNLEKM------CRSLE 1256
Query: 247 EKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVI----QSKDATIQELK 302
++ + L+ + + I+ L Q + + QL A++ +SK A+ Q+++
Sbjct: 1257 DQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIE 1316
Query: 303 EKIAYLEAE 311
E LE E
Sbjct: 1317 ELKHQLEEE 1325
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 57.4 bits (137), Expect = 2e-08
Identities = 58/274 (21%), Positives = 119/274 (43%), Gaps = 35/274 (12%)
Query: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 122
+K E + L E+ ++E + L K ++ + + L D +QV +K NG
Sbjct: 971 EKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDD------LQVEEDKVNGL 1024
Query: 123 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 182
+ L +D+E + + L A L+ AKR+ + D + ++ + +
Sbjct: 1025 IKINAKLEQQ--------TDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLEND 1076
Query: 183 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 242
+Q E+++++KE E+ +LQ ++ + K++E + +EEL +
Sbjct: 1077 KQQI-------EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEE---EI 1126
Query: 243 QAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS-----KDAT 297
+AE A +EK+ + L ++ + + L+ IE + +A Q ++AT
Sbjct: 1127 EAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEAT 1186
Query: 298 IQE------LKEKIAYLEAENLEMHDRMEHLIEK 325
+Q L++K A AE E D ++ + +K
Sbjct: 1187 LQHEATAATLRKKQADSVAELGEQIDNLQRVKQK 1220
Score = 54.3 bits (129), Expect = 2e-07
Identities = 60/290 (20%), Positives = 120/290 (41%), Gaps = 23/290 (7%)
Query: 41 ELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD 100
EL + E +I K + E+ Q++ E + + LQ R D +
Sbjct: 1290 ELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE 1349
Query: 101 RNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCIN-EDVESLRKTVQDLLAKLQ 159
+ + + E+Q L K N S A + + E D E++E +K + L + +
Sbjct: 1350 QYEEEQEAKAELQRALSKAN----SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAE 1405
Query: 160 EAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQ 219
E S C + E T R Q E E L R+ +R A + + QR
Sbjct: 1406 ENTETANSKCASLEKTKQRLQGEVED----LMRDLERSHTACATLDKKQRNF-------D 1454
Query: 220 ALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQ 279
+LA+ + ++L + A+ +A ++++ +L E+ +R + D L++ +R+ +
Sbjct: 1455 KVLAEWK------QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKN 1508
Query: 280 MIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISH 329
+ E++ + I +QE ++ +E E ++ +E +E + H
Sbjct: 1509 LQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEE-VEGSLEH 1557
Score = 35.8 bits (81), Expect = 0.062
Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 155 LAKLQEAKRQHQSDCVAFEVTLSRYQR------EAEQSNVALQREED----RVEQKEAEV 204
L K EA+++ + FE T R E E+ V+L +E++ +V+ + +
Sbjct: 843 LLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENL 902
Query: 205 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 264
+ + R G+ L AKV+E LEE N++ A K LE + + L+ I
Sbjct: 903 MDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVA---KKRNLEDKCSSLKRDID 959
Query: 265 HLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQEL-KEKIAYLEAENLEMHD 317
L+ L +++ +++N + + + I +L KEK + EA + D
Sbjct: 960 DLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDD 1013
Score = 32.3 bits (72), Expect = 0.69
Identities = 43/172 (25%), Positives = 77/172 (44%), Gaps = 30/172 (17%)
Query: 178 RYQREAEQSN--VALQRE-EDRVEQKEAEVGELQRRLLGMETEHQALLAKVR---EGEVA 231
R + E E ++ VA +R ED+ + ++ +L+ L +E E A KV+ E A
Sbjct: 929 RLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTA 988
Query: 232 LEELRSNNA---------------DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRK 276
LEE S D Q E +K L K A L ++ L+ L+ Q++K
Sbjct: 989 LEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLE-QEKK 1047
Query: 277 VRQMIEQ--------LQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRME 320
+R +E+ L+ S+ I + Q+++EK+ E E ++ +++
Sbjct: 1048 LRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKID 1099
>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
Length = 762
Score = 57.4 bits (137), Expect = 2e-08
Identities = 56/231 (24%), Positives = 101/231 (43%), Gaps = 30/231 (12%)
Query: 142 EDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKE 201
E V+ K + +L K Q+ Q++ E TL RY + Q++ +++ E
Sbjct: 446 ERVKGRDKHINNLKKKCQKESEQNREKQQRIE-TLERYLADLPTLEDH-QKQSQQLKDSE 503
Query: 202 AEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQA-----------EREKAA 250
+ ELQ ++ +E+ + A RE E+ LE LR A+ + E
Sbjct: 504 LKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSLQDKQSVEETSGE 563
Query: 251 TLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEK------ 304
E E+ +++ L +++ QQ+K+ Q+ Q+Q+ + + ++ T Q L+E+
Sbjct: 564 GPEVEMESWQKRYDSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGTSQALREEAQRRDS 623
Query: 305 -IAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSIRISKPPSP 354
+ L E+ + + LIEK N + Q + PGS PPSP
Sbjct: 624 ALQQLRTAVKELSVQNQDLIEK-----NLTLQEHLRQAQPGS-----PPSP 664
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/206 (20%), Positives = 91/206 (44%), Gaps = 21/206 (10%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT 127
+K+IN LK + Q E Q+ E L+R L D ++ Q ++ T
Sbjct: 452 DKHINNLKKKCQKESEQNREKQQRIET----LERYLADLPTLEDHQKQSQQLKDSELKST 507
Query: 128 ALYSSPPEVDTCINE----------DVESLRKTVQDLLA---KLQEAKRQHQSDCVAFEV 174
L E+++ + E +ESLR+ + + LQ+ + ++ EV
Sbjct: 508 ELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEV 567
Query: 175 TLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEE 234
+ +Q+ + +++++ +++Q ++V L++ + E QAL + + + AL++
Sbjct: 568 EMESWQKRYDSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGTSQALREEAQRRDSALQQ 627
Query: 235 LRSNNADCQAER----EKAATLEKEV 256
LR+ + + EK TL++ +
Sbjct: 628 LRTAVKELSVQNQDLIEKNLTLQEHL 653
Score = 37.0 bits (84), Expect = 0.028
Identities = 34/143 (23%), Positives = 72/143 (50%), Gaps = 10/143 (6%)
Query: 190 LQREEDRVEQKEAEVGELQRRLLGMETE-HQALLAKVRE-GEVAL---EELRSNNADCQA 244
L+ +E ++++ + +L++++ E + H ALL + G+V L +EL+ N +A
Sbjct: 337 LKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRA 396
Query: 245 E-REKAATLEKEVAGLREKIH--HLDDMLKSQQRKV--RQMIEQLQNSKAVIQSKDATIQ 299
+ +K L +E L +K+ ++ L + KV ++ E+++ + ++ +D I
Sbjct: 397 QFAQKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHIN 456
Query: 300 ELKEKIAYLEAENLEMHDRMEHL 322
LK+K +N E R+E L
Sbjct: 457 NLKKKCQKESEQNREKQQRIETL 479
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 57.4 bits (137), Expect = 2e-08
Identities = 62/315 (19%), Positives = 137/315 (43%), Gaps = 31/315 (9%)
Query: 23 RKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQ 82
+KT A+ HS +EL E+ E+++ L+ G+ LKS ++ +Q
Sbjct: 1036 KKTNAVKELEKLQHSTETELTEALQ-KREVLETELQNAHGE----------LKSTLRQLQ 1084
Query: 83 EARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLE-KPNGFSQSPTALYSSPPEVDTCIN 141
E R+ LQK + + K + +E ++ +E K + AL N
Sbjct: 1085 ELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKER--------N 1136
Query: 142 EDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKE 201
+++ V L ++E + + + + E TL + + E ++ N ++ D+++ +
Sbjct: 1137 WELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAK 1196
Query: 202 AEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQ----AEREKAATLEKEVA 257
++ E + +L E E L ++ + ++E+ S + + + ++A L +E+
Sbjct: 1197 EQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELR 1256
Query: 258 GLREKIHHLDDMLKSQ-------QRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEA 310
RE++ + L QR++ ++ +L++ K + + KDA L E++ +
Sbjct: 1257 LTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKV 1316
Query: 311 ENLEMHDRMEHLIEK 325
+ RM+ I+K
Sbjct: 1317 REAHLEARMQAEIKK 1331
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/245 (21%), Positives = 105/245 (42%), Gaps = 33/245 (13%)
Query: 81 IQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCI 140
+ E+R + KL ++ +K D + R + ++ E + + + +D C
Sbjct: 451 LTESRQSILKLESELENK------DEILRDKFSLMNEN----RELKVRVAAQNERLDLC- 499
Query: 141 NEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRV--- 197
+++ES R ++ L + + + + F+ LS+YQ + +EDR
Sbjct: 500 QQEIESSRVELRSLEKIISQLPLKRE--LFGFKSYLSKYQMSS------FSNKEDRCIGC 551
Query: 198 -EQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEV 256
E + + EL+ +L E E Q L A + +++ + N++ E K ++LE E
Sbjct: 552 CEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQ---ESSKLSSLETEP 608
Query: 257 AGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMH 316
L H + + +K Q + + + + V I+EL+ K+ +EAEN ++
Sbjct: 609 VKLGG--HQVAESVKDQNQHTMNKQYEKERQRLV-----TGIEELRTKLIQIEAENSDLK 661
Query: 317 DRMEH 321
M H
Sbjct: 662 VNMAH 666
Score = 43.9 bits (102), Expect = 2e-04
Identities = 50/258 (19%), Positives = 113/258 (43%), Gaps = 22/258 (8%)
Query: 73 QLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLE--------KPNGFSQ 124
Q+K E+ +E L K+ ++I ++H ++ ++L+ K N +
Sbjct: 987 QVKIEMDQYKEE---LSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKE 1043
Query: 125 SPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAE 184
+S+ E+ + + E L +Q+ +L+ RQ Q L + Q E
Sbjct: 1044 LEKLQHSTETELTEALQKR-EVLETELQNAHGELKSTLRQLQE----LRDVLQKAQLSLE 1098
Query: 185 QSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQA 244
+ ++ + + + E+ + ++ LL M+ QAL K R E+ + + D
Sbjct: 1099 EKYTTIKDLTAELRECKMEIEDKKQELLEMD---QAL--KERNWELKQRAAQVTHLDMTI 1153
Query: 245 EREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEK 304
RE +E+++ L + + LK +++ + ++LQN+K ++ K+ + + +++
Sbjct: 1154 -REHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQE 1212
Query: 305 IAYLEAENLEMHDRMEHL 322
I+ L+ E RM+ +
Sbjct: 1213 ISQLKKEIERTQQRMKEM 1230
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/121 (20%), Positives = 67/121 (55%), Gaps = 4/121 (3%)
Query: 194 EDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLE 253
+ ++ ++ +L+++ + T++ +L+ K L + R+ + ++ +++AA+
Sbjct: 228 DQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAAS-- 285
Query: 254 KEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENL 313
V L E+I +L+ + +Q + +R+ +L+ S+ ++ K+ ++QE KE+ L+ + L
Sbjct: 286 --VPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLL 343
Query: 314 E 314
E
Sbjct: 344 E 344
Score = 36.6 bits (83), Expect = 0.036
Identities = 55/274 (20%), Positives = 124/274 (45%), Gaps = 39/274 (14%)
Query: 70 NINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTAL 129
N+ S+ Q IQE L+K SSKL+ + + + LEK +
Sbjct: 663 NMAHRTSQFQLIQE--ELLEKASN--SSKLESEMTKKCSQL---LTLEKQ---LEEKIVA 712
Query: 130 YSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFE----VTLSRY---QRE 182
YSS + + +++ + ++ L + +H+ C+AFE + L ++ +++
Sbjct: 713 YSSIAAKNAELEQELMEKNEKIRSLETNINT---EHEKICLAFEKAKKIHLEQHKEMEKQ 769
Query: 183 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQAL--LAKVREGEVALEELRSNNA 240
E+ L++++ + +++E + LQ+ ++ + ++L L +GE+ E ++ +
Sbjct: 770 IERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKD-- 827
Query: 241 DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSK----AVIQSKDA 296
E L+ +V+ K+ LD L+ + ++ + QL+ +K ++ K
Sbjct: 828 ------EALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSE 881
Query: 297 TI----QELKEKIAYLEAENLEMHDRMEHLIEKQ 326
+ +ELK K L+ E E + ++H +++Q
Sbjct: 882 EVYCLQKELKIKNHSLQ-ETSEQNVILQHTLQQQ 914
Score = 36.2 bits (82), Expect = 0.047
Identities = 68/328 (20%), Positives = 130/328 (39%), Gaps = 29/328 (8%)
Query: 33 SAGHSLASELVESHDG------HEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARN 86
S L ++ SH G +E + K+ K +K + Q I+ R
Sbjct: 177 SRSEKLILDVQPSHPGLLNYSPYENVCKISGSSTDFQKKPRDKMFSSSAPVDQEIKSLRE 236
Query: 87 CLQKLREDISSKLDRNLG-----DSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCIN 141
L KLR+ + + +N +S+H E+ K + + S P + IN
Sbjct: 237 KLNKLRQQNACLVTQNHSLMTKFESIHF-ELTQSRAKVSMLESAQQQAASVPILEEQIIN 295
Query: 142 EDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQ-K 200
+ E + QD + + E K + V + + Q E ++ + D +EQ K
Sbjct: 296 LEAEV---SAQDKVLREAENKLEQSQKMV-----IEKEQSLQESKEECIKLKVDLLEQTK 347
Query: 201 EAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLR 260
+ + E QR E + + + +VA E+L A+ + EKE L+
Sbjct: 348 QGKRAERQRNEALYNAEELSKAFQQYKKKVA-EKLEKVQAEEEILERNLTNCEKENKRLQ 406
Query: 261 EKIHHLDDMLKSQQRKVRQMIEQLQNSK-----AVIQSKDATIQELKEKIAYLEAENLEM 315
E+ L+ + K+RQ+ E+ N K +++ + Q + + + L+ E+ E+
Sbjct: 407 ERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLES-EL 465
Query: 316 HDRMEHLIEK-QISHGNFSTQARAKTEN 342
++ E L +K + + N + R +N
Sbjct: 466 ENKDEILRDKFSLMNENRELKVRVAAQN 493
Score = 32.0 bits (71), Expect = 0.90
Identities = 36/154 (23%), Positives = 67/154 (43%), Gaps = 18/154 (11%)
Query: 178 RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRS 237
+Y++E ++ ++ ++ Q EAE +L+ + ++ Q + + L E S
Sbjct: 631 QYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLI-------QEELLEKAS 683
Query: 238 NNADCQAEREKAA----TLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS 293
N++ ++E K TLEK+ L EKI S K ++ ++L I+S
Sbjct: 684 NSSKLESEMTKKCSQLLTLEKQ---LEEKIV----AYSSIAAKNAELEQELMEKNEKIRS 736
Query: 294 KDATIQELKEKIAYLEAENLEMHDRMEHLIEKQI 327
+ I EKI + ++H +EKQI
Sbjct: 737 LETNINTEHEKICLAFEKAKKIHLEQHKEMEKQI 770
>gi|226495417 coiled-coil domain containing 102A [Homo sapiens]
Length = 550
Score = 57.0 bits (136), Expect = 3e-08
Identities = 55/194 (28%), Positives = 92/194 (47%), Gaps = 20/194 (10%)
Query: 145 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRY---QREAEQSNVALQREEDRVEQKE 201
E L KT Q++L +L K HQ + L + ++ L+ E +R++ +
Sbjct: 295 EELSKTKQEMLKQLSILKEAHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAEN 354
Query: 202 AEVGELQRRL----LGMETEHQALLAKVREGEVALEELRSNNA---DCQAEREKAATLEK 254
A + RL LG+E E++ L A+V + E AL R A DC +AA EK
Sbjct: 355 AAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQTASALDCDLRASQAALFEK 414
Query: 255 --EVAGLREKIHHLDDMLKSQ-QRKVRQMIE---QLQNSKAVIQSKDATIQELKEKIAYL 308
E+A L+ H+ LK Q Q KV ++ +++ +A ++ ++ELK+++A
Sbjct: 415 NKELADLK----HVHGKLKKQFQEKVAELAHANRRVEQHEAEVKKLRLRVEELKKELAQA 470
Query: 309 EAENLEMHDRMEHL 322
E E E H++ L
Sbjct: 471 EDELDEAHNQARKL 484
Score = 37.0 bits (84), Expect = 0.028
Identities = 34/146 (23%), Positives = 72/146 (49%), Gaps = 14/146 (9%)
Query: 198 EQKEAEVGELQRRLLGMETEHQALLAKVREGEVAL----EELRSNNADCQAEREKAATLE 253
E++ +++ L+ RL E Q +L K RE ++AL E+L + + + E+ + +
Sbjct: 246 EEEASKLTALRLRL----DESQKVLLKEREDKLALSRNIEKLEGELSQWKIKYEELSKTK 301
Query: 254 KEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENL 313
+E+ + L + ++ Q ++ +M E L++ S D + EL+ ++ L+AEN
Sbjct: 302 QEM------LKQLSILKEAHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENA 355
Query: 314 EMHDRMEHLIEKQISHGNFSTQARAK 339
R E L +++ + + RA+
Sbjct: 356 AEWGRRERLETEKLGLERENKKLRAQ 381
Score = 32.0 bits (71), Expect = 0.90
Identities = 47/241 (19%), Positives = 89/241 (36%), Gaps = 38/241 (15%)
Query: 40 SELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISS-- 97
S L E+H + L+ G + ++ + +L+ E++ +Q RE + +
Sbjct: 309 SILKEAHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEK 368
Query: 98 --------KLDRNLGD---SLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVES 146
KL +GD +L R+ Q S AL+ E+ +
Sbjct: 369 LGLERENKKLRAQVGDLEEALARRRRQTASALDCDLRASQAALFEKNKELAD-LKHVHGK 427
Query: 147 LRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGE 206
L+K Q+ +A+L A R+ + E + + + E+ L + ED +++ + +
Sbjct: 428 LKKQFQEKVAELAHANRRVEQH----EAEVKKLRLRVEELKKELAQAEDELDEAHNQARK 483
Query: 207 LQRRL---------LGMETEH-----------QALLAKVREGEVALEELRSNNADCQAER 246
LQR L L ++ EH L K+R EE +D +
Sbjct: 484 LQRSLDEQTEQSENLQVQLEHLQSRLRRQQQNAPLFGKIRSARFGTEEAEDGTSDLDEDE 543
Query: 247 E 247
+
Sbjct: 544 D 544
>gi|188528616 testis specific, 10 [Homo sapiens]
Length = 698
Score = 57.0 bits (136), Expect = 3e-08
Identities = 59/277 (21%), Positives = 123/277 (44%), Gaps = 36/277 (12%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT 127
++++ + K E+Q QE CL E I + +N+ R+EI ++ N ++
Sbjct: 218 QRHLAKKKYELQLTQEKIMCLD---EKIDNFTRQNIAQ---REEISILGGTLNDLAKEKE 271
Query: 128 ALYS---SPPEVDTCINEDVESLRKTV---QDLLAKLQEAKRQHQSDCVAFEVTLSRYQR 181
L + E + E + KT+ ++++A++++A RQ + E +SR +R
Sbjct: 272 CLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVSRMRR 331
Query: 182 EAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNAD 241
+ +++N L + + + LQ + + E+QAL K+ + L +++ D
Sbjct: 332 QLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQD 391
Query: 242 CQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQL-------QNSKAVIQSK 294
E ++ L ++LKS++ + RQM+EQL +N + +
Sbjct: 392 TNLE-----------------VNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQS 434
Query: 295 DATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGN 331
+A LK ++ EAE + ++++ L + H N
Sbjct: 435 EADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLN 471
Score = 42.4 bits (98), Expect = 7e-04
Identities = 52/221 (23%), Positives = 92/221 (41%), Gaps = 50/221 (22%)
Query: 141 NEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAE--QSNV-ALQREEDRV 197
N DVE L+ T +D + + C+ L +Y+R Q NV L+ E D++
Sbjct: 20 NCDVELLKTTTRD----------REELKCM-----LEKYERHLAEIQGNVKVLKSERDKI 64
Query: 198 ----EQKEAEVGELQRRLLGM-----ETEHQALLAKVR-EGEVALEELRSNNADCQAERE 247
EQ + E+ L+R ++ T A+L +V E +VA +LR + + RE
Sbjct: 65 FLLYEQAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRE 124
Query: 248 KA-----------ATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDA 296
+ A LE+ + L +H+LDD Q + M E + + ++S
Sbjct: 125 RLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLAR 184
Query: 297 TIQELKEKIAYLEAEN-----------LEMHDRMEHLIEKQ 326
+ + ++ +AEN ++ D HL +K+
Sbjct: 185 KAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK 225
>gi|13376858 testis specific, 10 [Homo sapiens]
Length = 698
Score = 57.0 bits (136), Expect = 3e-08
Identities = 59/277 (21%), Positives = 123/277 (44%), Gaps = 36/277 (12%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT 127
++++ + K E+Q QE CL E I + +N+ R+EI ++ N ++
Sbjct: 218 QRHLAKKKYELQLTQEKIMCLD---EKIDNFTRQNIAQ---REEISILGGTLNDLAKEKE 271
Query: 128 ALYS---SPPEVDTCINEDVESLRKTV---QDLLAKLQEAKRQHQSDCVAFEVTLSRYQR 181
L + E + E + KT+ ++++A++++A RQ + E +SR +R
Sbjct: 272 CLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVSRMRR 331
Query: 182 EAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNAD 241
+ +++N L + + + LQ + + E+QAL K+ + L +++ D
Sbjct: 332 QLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQD 391
Query: 242 CQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQL-------QNSKAVIQSK 294
E ++ L ++LKS++ + RQM+EQL +N + +
Sbjct: 392 TNLE-----------------VNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQS 434
Query: 295 DATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGN 331
+A LK ++ EAE + ++++ L + H N
Sbjct: 435 EADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLN 471
Score = 42.4 bits (98), Expect = 7e-04
Identities = 52/221 (23%), Positives = 92/221 (41%), Gaps = 50/221 (22%)
Query: 141 NEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAE--QSNV-ALQREEDRV 197
N DVE L+ T +D + + C+ L +Y+R Q NV L+ E D++
Sbjct: 20 NCDVELLKTTTRD----------REELKCM-----LEKYERHLAEIQGNVKVLKSERDKI 64
Query: 198 ----EQKEAEVGELQRRLLGM-----ETEHQALLAKVR-EGEVALEELRSNNADCQAERE 247
EQ + E+ L+R ++ T A+L +V E +VA +LR + + RE
Sbjct: 65 FLLYEQAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRE 124
Query: 248 KA-----------ATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDA 296
+ A LE+ + L +H+LDD Q + M E + + ++S
Sbjct: 125 RLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLAR 184
Query: 297 TIQELKEKIAYLEAEN-----------LEMHDRMEHLIEKQ 326
+ + ++ +AEN ++ D HL +K+
Sbjct: 185 KAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK 225
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 57.0 bits (136), Expect = 3e-08
Identities = 65/315 (20%), Positives = 138/315 (43%), Gaps = 46/315 (14%)
Query: 38 LASELVES--HDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI 95
+ +EL++S D + LK R E + LK + +++ L+K+ D+
Sbjct: 623 IRNELMQSLNQDSNSNFKDTLLKER-------EAEVRNLKQNLSELEQLNENLKKVAFDV 675
Query: 96 SSKLDRN-LGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDL 154
+ ++ L R +++ L N S + VE+L+ ++
Sbjct: 676 KMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTI--------------VETLKMEKGEI 721
Query: 155 LAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRV----EQKEAEVGELQRR 210
A+L AK++ + +E T+ + ALQ E + + ++K+ E+ EL++
Sbjct: 722 EAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKN 781
Query: 211 LLGMETEHQA--------------LLAKVREGEVALEELRSNNADCQAEREKAATLEKEV 256
+ M+T+H+ L + + E+ +E+L+ ++ Q E +K + ++
Sbjct: 782 IEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKN 841
Query: 257 AGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELK--EKIAYLEAENLE 314
LR+ I D L S + + + E+L+ + QS+ A + + K + + L +E +
Sbjct: 842 EILRQTIEEKDRSLGSMKEENNHLQEELERLREE-QSRTAPVADPKTLDSVTELASEVSQ 900
Query: 315 MHDRMEHLIEKQISH 329
++ EHL E++I H
Sbjct: 901 LNTIKEHL-EEEIKH 914
Score = 47.8 bits (112), Expect = 2e-05
Identities = 49/280 (17%), Positives = 124/280 (44%), Gaps = 24/280 (8%)
Query: 47 DGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDS 106
D EI++ L + D + E N+ +LK ++ +++ ++ L + +E++ L +
Sbjct: 396 DAENEIMR--LSSLNQDNSLAEDNL-KLKMRIEVLEKEKSLLSQEKEELQMSLLKL---- 448
Query: 107 LHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQ 166
E +V+ + L+ ++ E +S+ + + L+A+++E RQ+Q
Sbjct: 449 --NNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEK-ETLIAEIEELDRQNQ 505
Query: 167 SDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVR 226
+ + ++ + + + + + + ++ V +L+ + + E K+
Sbjct: 506 EATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLI 565
Query: 227 EGEVALEELRSNNADCQAE-----------REKAATLEKEVAGLREKIHHLDDMLKSQQR 275
+ EVAL +L + + +E +++KE L+E I ++ L +
Sbjct: 566 QSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRN 625
Query: 276 KVRQMIEQLQNSK---AVIQSKDATIQELKEKIAYLEAEN 312
++ Q + Q NS +++ ++A ++ LK+ ++ LE N
Sbjct: 626 ELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLN 665
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/274 (20%), Positives = 111/274 (40%), Gaps = 32/274 (11%)
Query: 68 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNG--FSQS 125
+K Q+K ++ Q+ +Q ++ + + L + LH+ + QV+++ N
Sbjct: 1212 DKLKQQVKKMEEWKQQVMTTVQNMQHESAQ-----LQEELHQLQAQVLVDSDNNSKLQVD 1266
Query: 126 PTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQ 185
T L S + +T + + L + VQ + +L K LS Q
Sbjct: 1267 YTGLIQSYEQNETKLKNFGQELAQ-VQHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQ 1325
Query: 186 SNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNN------ 239
S L+ + V + +E+ ++ E + L ++E + + L+ NN
Sbjct: 1326 SAECLRASKSEVLSESSEL---------LQQELEELRKSLQEKDATIRTLQENNHRLSDS 1376
Query: 240 --ADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSK--- 294
A + ER++ + E+ L+EK L +LK + ++ +QL +S +K
Sbjct: 1377 IAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNE 1436
Query: 295 ----DATIQELKEKIAYLEAENLEMHDRMEHLIE 324
+ LKE+I LE + ++ E ++E
Sbjct: 1437 NELLRQAVTNLKERILILEMDIGKLKGENEKIVE 1470
Score = 42.4 bits (98), Expect = 7e-04
Identities = 70/344 (20%), Positives = 139/344 (40%), Gaps = 69/344 (20%)
Query: 36 HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI 95
H L ++++ D + ++ Y +G +E+N +LK+ Q + + ++ + +L
Sbjct: 1247 HQLQAQVLVDSDNNSKLQVDY----TGLIQSYEQNETKLKNFGQELAQVQHSIGQL---- 1298
Query: 96 SSKLDRNLG--DSLHRQEIQVVLEKPNGFSQSPTALYSSPPEV----DTCINEDVESLRK 149
+ D LG D + Q L P QS L +S EV + +++E LRK
Sbjct: 1299 CNTKDLLLGKLDIISPQLSSASLLTP----QSAECLRASKSEVLSESSELLQQELEELRK 1354
Query: 150 TVQDLLAKLQEAKRQHQ--SDCVAFEVTLSRYQREAEQSNVALQREEDRVEQK------- 200
++Q+ A ++ + + SD +A L R + E S + +E+ V QK
Sbjct: 1355 SLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDL 1414
Query: 201 --------------------------EAEVGELQRRLLGMETEHQALLAKVR-EGEVALE 233
V L+ R+L +E + + K++ E E +E
Sbjct: 1415 LIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMD----IGKLKGENEKIVE 1470
Query: 234 ELRSNNADCQAEREKAATL-------EKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQN 286
R + QA +E E E ++EK + +LK +++ + QL N
Sbjct: 1471 TYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLLKEKEQGKTGELNQLLN 1530
Query: 287 SKAVIQSKDATIQELKEKIAYL----EAENLEMHDRMEHLIEKQ 326
+ +Q K Q+ ++++ + EN + + ++ L +K+
Sbjct: 1531 AVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKE 1574
Score = 38.9 bits (89), Expect = 0.007
Identities = 69/311 (22%), Positives = 127/311 (40%), Gaps = 56/311 (18%)
Query: 66 IHEKNINQLKSEVQYIQEARNCLQKLRED----ISSKLDRNLG-----------DSLHRQ 110
+ K Q SE++ ++E ++ LQKL ++ I +K D+ L + L RQ
Sbjct: 1383 LERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQ 1442
Query: 111 EIQVVLEKPNGFSQSPTALYSSPPE-VDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDC 169
+ + E+ L + V+T ++ E + +Q+ K R+ + +C
Sbjct: 1443 AVTNLKERILILEMDIGKLKGENEKIVETYRGKETE--YQALQETNMKFSMMLREKEFEC 1500
Query: 170 -------VAFEVTLSRYQ--------------REAEQSNVALQREEDRV----EQKEAEV 204
+AFE L + + ++ V Q+E D+V +QK+ E
Sbjct: 1501 HSMKEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMEN 1560
Query: 205 GELQ---RRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLRE 261
LQ +RL E L ++R LE S + A ++ A L K+V L E
Sbjct: 1561 TALQNEVQRLRDKEFRSNQELERLRNH--LLESEDSYTREALAAEDREAKLRKKVTVLEE 1618
Query: 262 KIHHLDDMLKSQQRKVRQMIEQLQNSKAVI-QSKDATIQEL-----KEKIAYLEAENLEM 315
K+ + +++ + +E LQ V+ + +D T +L + K L NL+M
Sbjct: 1619 KLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQM 1678
Query: 316 HDRMEHLIEKQ 326
+EH +++
Sbjct: 1679 --VLEHFQQEE 1687
Score = 37.7 bits (86), Expect = 0.016
Identities = 73/363 (20%), Positives = 144/363 (39%), Gaps = 68/363 (18%)
Query: 11 VDVHPEDQAAAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKN 70
+D H + + ++ S H EL + + EE+ + +G SG
Sbjct: 229 IDDHQHEMSVLQNAHQQKLTEISRRHR--EELSDYEERIEELENLLQQGGSGVIETDLSK 286
Query: 71 INQLKSEVQYIQ----EARNCLQKLRE---DISSKLD--RNLGDSLHRQEIQVVLEK--- 118
I +++ +Q +Q E+ +++L + DI+ KL N D L R++ Q+ +EK
Sbjct: 287 IYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQI 346
Query: 119 ---------------PNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKR 163
P+ QS T + E+V L++ + D ++
Sbjct: 347 MEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSS 406
Query: 164 QHQSDCVAFEVTLSRYQR----EAEQSNVALQREEDRVE----QKEAEV----------- 204
+Q + +A E L R E E+S ++ ++EE ++ E EV
Sbjct: 407 LNQDNSLA-EDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISL 465
Query: 205 -GELQRRLLGMETEHQALLAKVREGEVAL---EELRSNNADC---------QAEREK--- 248
EL L +E + Q L + E E + EEL N + Q +++
Sbjct: 466 DSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEG 525
Query: 249 ---AATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI 305
+ L++++ ++++H L+D +++ E+L S+ + T Q+L++K+
Sbjct: 526 DSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKV 585
Query: 306 AYL 308
L
Sbjct: 586 ENL 588
Score = 36.2 bits (82), Expect = 0.047
Identities = 59/296 (19%), Positives = 123/296 (41%), Gaps = 64/296 (21%)
Query: 71 INQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALY 130
++QL + ++++E QK+ ED +N Q +Q ++ + F +
Sbjct: 898 VSQLNTIKEHLEEEIKHHQKIIED------QNQSKMQLLQSLQEQKKEMDEFRYQHEQMN 951
Query: 131 SSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSD-CVAFEVT-------------- 175
++ ++ +E+++SL+KT++ + +L E ++ Q+D F+ T
Sbjct: 952 ATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKH 1011
Query: 176 -LSRYQREA---------------EQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQ 219
LS+ + E + N++L ++ D++ + E VG+L + + + E Q
Sbjct: 1012 DLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDE--VGKLTQIIQQKDLEIQ 1069
Query: 220 ALLAKVREGEVALEE--LRSNNADCQAEREKAATL----EKEVAGLREKIHHLDDM---- 269
AL A++ + L+ EREK + +E + L+ + H + D+
Sbjct: 1070 ALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAK 1129
Query: 270 ------LKSQQRKVRQMIEQ---------LQNSKAVIQSKDATIQELKEKIAYLEA 310
L+ + +K+ E +QN +I+ KD I L +K L A
Sbjct: 1130 EAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLA 1185
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.341
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,038,802
Number of Sequences: 37866
Number of extensions: 562322
Number of successful extensions: 7371
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 359
Number of HSP's successfully gapped in prelim test: 729
Number of HSP's that attempted gapping in prelim test: 3323
Number of HSP's gapped (non-prelim): 3080
length of query: 365
length of database: 18,247,518
effective HSP length: 104
effective length of query: 261
effective length of database: 14,309,454
effective search space: 3734767494
effective search space used: 3734767494
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.