Guide to the Human Genome
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Search of human proteins with 103471997

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]
         (1720 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]          3459   0.0  
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]            425   e-118
gi|39725938 polymerase (RNA) III (DNA directed) polypeptide A, 1...   403   e-112
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    60   1e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    59   5e-08
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    56   3e-07
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    53   2e-06
gi|215422388 death-domain associated protein isoform a [Homo sap...    53   2e-06
gi|215422366 death-domain associated protein isoform b [Homo sap...    53   2e-06
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     53   3e-06
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     53   3e-06
gi|115529449 upstream binding transcription factor, RNA polymera...    53   3e-06
gi|115529451 upstream binding transcription factor, RNA polymera...    53   3e-06
gi|7657671 upstream binding transcription factor, RNA polymerase...    53   3e-06
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    53   3e-06
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    53   3e-06
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    53   3e-06
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    53   3e-06
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    53   3e-06
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    53   3e-06
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    52   4e-06
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    52   4e-06
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          52   4e-06
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    52   5e-06
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                51   8e-06
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    51   1e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           51   1e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           51   1e-05
gi|21361639 DIPB protein [Homo sapiens]                                50   1e-05
gi|17975763 myelin transcription factor 1 [Homo sapiens]               50   1e-05

>gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]
          Length = 1720

 Score = 3459 bits (8970), Expect = 0.0
 Identities = 1720/1720 (100%), Positives = 1720/1720 (100%)

Query: 1    MLISKNMPWRRLQGISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPADS 60
            MLISKNMPWRRLQGISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPADS
Sbjct: 1    MLISKNMPWRRLQGISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPADS 60

Query: 61   KEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLL 120
            KEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLL
Sbjct: 61   KEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLL 120

Query: 121  LCQLRVLEVGALQAVYELERILNRFLEENPDPSASEIREELEQYTTEIVQNNLLGSQGAH 180
            LCQLRVLEVGALQAVYELERILNRFLEENPDPSASEIREELEQYTTEIVQNNLLGSQGAH
Sbjct: 121  LCQLRVLEVGALQAVYELERILNRFLEENPDPSASEIREELEQYTTEIVQNNLLGSQGAH 180

Query: 181  VKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRTAGQKDS 240
            VKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRTAGQKDS
Sbjct: 181  VKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRTAGQKDS 240

Query: 241  EPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRFNPSVFFLD 300
            EPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRFNPSVFFLD
Sbjct: 241  EPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRFNPSVFFLD 300

Query: 301  FLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTT 360
            FLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTT
Sbjct: 301  FLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTT 360

Query: 361  DEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYPGIRQI 420
            DEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYPGIRQI
Sbjct: 361  DEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYPGIRQI 420

Query: 421  LEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQEL 480
            LEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQEL
Sbjct: 421  LEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQEL 480

Query: 481  RQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCR 540
            RQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCR
Sbjct: 481  RQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCR 540

Query: 541  HVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQ 600
            HVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQ
Sbjct: 541  HVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQ 600

Query: 601  SELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRG 660
            SELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRG
Sbjct: 601  SELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRG 660

Query: 661  LTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKET 720
            LTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKET
Sbjct: 661  LTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKET 720

Query: 721  PRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTC 780
            PRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTC
Sbjct: 721  PRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTC 780

Query: 781  LARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYD 840
            LARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYD
Sbjct: 781  LARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYD 840

Query: 841  EVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQS 900
            EVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQS
Sbjct: 841  EVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQS 900

Query: 901  GAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIK 960
            GAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIK
Sbjct: 901  GAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIK 960

Query: 961  PPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYG 1020
            PPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYG
Sbjct: 961  PPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYG 1020

Query: 1021 EDGLDIPKTQFLQPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHP 1080
            EDGLDIPKTQFLQPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHP
Sbjct: 1021 EDGLDIPKTQFLQPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHP 1080

Query: 1081 NTLLRRGAFLSYSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAA 1140
            NTLLRRGAFLSYSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAA
Sbjct: 1081 NTLLRRGAFLSYSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAA 1140

Query: 1141 ACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKW 1200
            ACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKW
Sbjct: 1141 ACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKW 1200

Query: 1201 QRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIK 1260
            QRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIK
Sbjct: 1201 QRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIK 1260

Query: 1261 TPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEKQNKFQVYQLRFQ 1320
            TPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEKQNKFQVYQLRFQ
Sbjct: 1261 TPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEKQNKFQVYQLRFQ 1320

Query: 1321 FLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNA 1380
            FLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNA
Sbjct: 1321 FLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNA 1380

Query: 1381 GELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEEN 1440
            GELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEEN
Sbjct: 1381 GELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEEN 1440

Query: 1441 DDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMER 1500
            DDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMER
Sbjct: 1441 DDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMER 1500

Query: 1501 RVQAVREIHPFIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGIT 1560
            RVQAVREIHPFIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGIT
Sbjct: 1501 RVQAVREIHPFIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGIT 1560

Query: 1561 RCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRV 1620
            RCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRV
Sbjct: 1561 RCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRV 1620

Query: 1621 IEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQF 1680
            IEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQF
Sbjct: 1621 IEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQF 1680

Query: 1681 LKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR 1720
            LKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR
Sbjct: 1681 LKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR 1720


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score =  425 bits (1092), Expect = e-118
 Identities = 384/1325 (28%), Positives = 594/1325 (44%), Gaps = 208/1325 (15%)

Query: 8    PWRRLQGISFGMYSAEELKKLSVKS--ITNPRYLDSLGNPSANGLYDLALGPADSKEVCS 65
            P R ++ + FG+ S +ELK++SV    I  P   +  G P   GL D   G  +    C 
Sbjct: 14   PLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEG-GRPKLGGLMDPRQGVIERTGRCQ 72

Query: 66   TCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLLLCQLR 125
            TC  + + C GH GHIEL   V     F   +L+     L C    C             
Sbjct: 73   TCAGNMTECPGHFGHIELAKPV-----FHVGFLVKTMKVLRCVCFFC------------- 114

Query: 126  VLEVGALQAVYELERILNRFLEENPDPSASEIREELEQYTTEIVQNNLLGSQGAHVKNVC 185
                             ++ L ++ +P   +I  + +    + + +     +G   KN+C
Sbjct: 115  -----------------SKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKG---KNIC 154

Query: 186  ESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRTAGQKDSEPLGI 245
            E   +         M+ K       G   + KE        +   + R+  +  +E   +
Sbjct: 155  EGGEE---------MDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHV 205

Query: 246  EEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRF-NPSVFFLDFLVV 304
             E    K+  L+P    E    +   E F L          GME R+  P    +  L V
Sbjct: 206  NEDSQEKKILLSPERVHEIFKRISDEECFVL----------GMEPRYARPEWMIVTVLPV 255

Query: 305  PPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTTDEEK 364
            PP   RP   +  Q     Q  +L   + D+V I   L    Q       +A        
Sbjct: 256  PPLSVRPAVVM--QGSARNQD-DLTHKLADIVKINNQLRRNEQNGAAAHVIAEDV----- 307

Query: 365  DSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKL--MMDK----YPGIR 418
                                 KL      LQ HV  + D+E+  L   M K       ++
Sbjct: 308  ---------------------KL------LQFHVATMVDNELPGLPRAMQKSGRPLKSLK 340

Query: 419  QILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQ 478
            Q L+ KEG  R ++MGKRVD++AR+VI PD  ++ +++G+P   A  +T+ + VTP+N+ 
Sbjct: 341  QRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNID 400

Query: 479  ELRQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKI- 537
             L++ V  G + +PGA  +I ++G R  L                      PKP    + 
Sbjct: 401  RLQELVRRGNSQYPGAKYIIRDNGDRIDLRF-------------------HPKPSDLHLQ 441

Query: 538  ----VCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDE 593
                V RH+ +GDI++ NRQPTLH+ S+  HR RILP     RL+ +    YNADFDGDE
Sbjct: 442  TGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWS-TFRLNLSVTTPYNADFDGDE 500

Query: 594  MNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHY 653
            MN H PQS   RAE   LA   +  + P+  +P+ G++QD + +    T R  F  R   
Sbjct: 501  MNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEV 560

Query: 654  MELVYRGLTDKVGRVKLLSPSILKPFPLWTGKQVVSTLL---INIIP--EDHIPLNLSGK 708
            M L+   L+   G+V    P+ILKP PLWTGKQ+ S ++   IN I     H     SG 
Sbjct: 561  MNLLMF-LSTWDGKVP--QPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGP 617

Query: 709  AKITGKAWVKETPRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEI 768
             K              PG       +++V++  GEL+ G+L K   G+SA  LVH  Y  
Sbjct: 618  YKHIS-----------PG-------DTKVVVENGELIMGILCKKSLGTSAGSLVHISYLE 659

Query: 769  YGGETSGKVLTCLARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVR 828
             G + +    + +  +   +L L  G T+G+ D +    AD K  + I+ +     Q V 
Sbjct: 660  MGHDITRLFYSNIQTVINNWL-LIEGHTIGIGDSI----ADSKTYQDIQNTIKKAKQDV- 713

Query: 829  AALNLPEAASYDEVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQ 888
              + + E A  +E+           +    N +   F+ +VN   N+             
Sbjct: 714  --IEVIEKAHNNEL-----------EPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSL 760

Query: 889  FPENSLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAG 948
               N+ + MV SGAKGS +N  Q+  ++GQ  +EG+R P     ++LP F   ++ P + 
Sbjct: 761  SEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESR 820

Query: 949  GFVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVR 1008
            GFV   +L G+ P EFFFH M GREGL+DTAVKT+ +GY+QR +IK +E ++V+YD TVR
Sbjct: 821  GFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVR 880

Query: 1009 DSDGSVVQFLYGEDGLDIPKTQF-----LQP------KQFPFLASNYEVI---MKSQHLH 1054
            +S   VVQ  YGEDGL     +F     L+P      K+F F  +N   +   ++   + 
Sbjct: 881  NSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVK 940

Query: 1055 EVLSRADPKKALHHFRAIKKWQSKHPNTLLRRGAFLSYSQKIQEAVKALKL-----ESEN 1109
            +VLS A  +  L      ++++    +  + R  F +   K+      L++     +  +
Sbjct: 941  DVLSNAHIQNELE-----REFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFH 995

Query: 1110 RNGRSPGTQEMLRMWYELDEESRRKYQKKAAACPDPSLSVWRPDIYFASVSETFETKVDD 1169
             N R P     +++   + E S+    K      D  LS        A  + T    +  
Sbjct: 996  INPRLPSDLHPIKVVEGVKELSK----KLVIVNGDDPLS------RQAQENATLLFNIHL 1045

Query: 1170 YSQEWAAQTEKSYEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLN 1229
             S   + +  + +  S  + D L   ++ K+ +++  PGE VG LAAQS+GEP+TQMTLN
Sbjct: 1046 RSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLN 1105

Query: 1230 TFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVL-NTKKALKRVKSLKKQLTRV 1288
            TFH+AG    NVTLG+PRL+E++ + S   KTP ++V +L  + +  +R K +  +L   
Sbjct: 1106 TFHYAGVSAKNVTLGVPRLKELINI-SKKPKTPSLTVFLLGQSARDAERAKDILCRLEHT 1164

Query: 1289 CLGEV 1293
             L +V
Sbjct: 1165 TLRKV 1169



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 49/156 (31%), Positives = 83/156 (53%), Gaps = 2/156 (1%)

Query: 1561 RCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRV 1620
            + ++ E    K  +E +L T+G++L  +    +V D  R  SNDI  I    GIEA  + 
Sbjct: 1319 KIIITEDGEFKALQEWILETDGVSLMRVLSEKDV-DPVRTTSNDIVEIFTVLGIEAVRKA 1377

Query: 1621 IEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGI-RSNSSPLQQMTFETSFQ 1679
            +E+E+  V +  G  V+ RHL+L+ D M   G    + R G+ R ++ PL + +FE +  
Sbjct: 1378 LERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVD 1437

Query: 1680 FLKQATMLGSHDELRSPSACLVVGKVVRGGTGLFEL 1715
             L +A   G  D ++  S  +++G++   GTG F+L
Sbjct: 1438 VLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDL 1473


>gi|39725938 polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
            [Homo sapiens]
          Length = 1390

 Score =  403 bits (1035), Expect = e-112
 Identities = 296/927 (31%), Positives = 444/927 (47%), Gaps = 137/927 (14%)

Query: 391  WIRLQSHVNIVFDSEMDKLMMDKYP-----GIRQILEKKEGLFRKHMMGKRVDYAARSVI 445
            W  LQ    +  +SE+  + ++  P     G  Q L+ K+G FR ++ GKRVD++ R+VI
Sbjct: 310  WDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVI 369

Query: 446  CPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRT 505
             PD  +  +E+ +P+  A  LT+P+ V   N+  LR+ V NGP VHPGA+ +        
Sbjct: 370  SPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPGANFI-------- 421

Query: 506  ALSAVDMTQREAVAKQLLTPATGAPKPQGTK---IVCRHVKNGDILLLNRQPTLHRPSIQ 562
                    QR    K+ L         Q  K   IV RH+ +GD++L NRQP+LH+ SI 
Sbjct: 422  -------QQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIM 474

Query: 563  AHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPK 622
            AH AR+ P  +  R +   C  YNADFDGDEMN H PQ+E  +AEA VL  T    + P+
Sbjct: 475  AHLARVKPH-RTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPR 533

Query: 623  DGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRGLT--DKVGRVKLLSPSILKPFP 680
            +G+PL   IQD +     +T +  FF R    +++   L   D+  +V+L  P+ILKP  
Sbjct: 534  NGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVT 593

Query: 681  LWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKETPRSVPGFNPDSMC--ESQVI 738
            LWTGKQ+ S +L    P D  P+  + + K  GK +  +          + +C  +S V 
Sbjct: 594  LWTGKQIFSVIL---RPSDDNPVRANLRTK--GKQYCGK---------GEDLCANDSYVT 639

Query: 739  IREGELLCGVLDKAHYGS-SAYGLVHCCYEIYGGETSGKVLTCLARLFTAYLQLYRGFTL 797
            I+  EL+ G +DK   GS S   + +     +G   +   ++ LARL   YL   RGF++
Sbjct: 640  IQNSELMSGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSRLARLAPVYLS-NRGFSI 698

Query: 798  GVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYDEVRGKWQDAHLGKDQRD 857
            G+ D+                    G   ++A   L   A Y +     +  + GK Q+ 
Sbjct: 699  GIGDVTP------------------GQGLLKAKYELLN-AGYKKCDEYIEALNTGKLQQQ 739

Query: 858  -----FNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQSGAKGSTVNTMQI 912
                    ++    +E++   +    AC    L      NS   M   G+KGS +N  Q+
Sbjct: 740  PGCTAEETLEALILKELSVIRDHAGSAC----LRELDKSNSPLTMALCGSKGSFINISQM 795

Query: 913  SCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIKPPEFFFHCMAGR 972
               +GQ  + G R P     +SLP FE +   P A GFV   F +G+ P EFFFH MAGR
Sbjct: 796  IACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGR 855

Query: 973  EGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFL 1032
            EGLVDTAVKT+ +GY+QR ++K LE L  QYDLTVR S G ++QF+YG DGLD    +  
Sbjct: 856  EGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEGK 915

Query: 1033 -QPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHPNTLLRRGAFLS 1091
             +P +F  +  N + +            ++P  + +      +   K    L  + +FL 
Sbjct: 916  DEPLEFKRVLDNIKAVFPCP--------SEPALSKNELILTTESIMKKSEFLCCQDSFLQ 967

Query: 1092 YSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAAACPDPSLSVWR 1151
              +K  + V     ++ ++ G +       R+ Y+LD  +  + +K    C D       
Sbjct: 968  EIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQVEKFLETCRD------- 1020

Query: 1152 PDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKWQRSLCEPGEAV 1211
                                          Y ++++                  EPG AV
Sbjct: 1021 -----------------------------KYMRAQM------------------EPGSAV 1033

Query: 1212 GLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLNT 1271
            G L AQSIGEP TQMTL TFHFAG   MN+TLG+PR++EI+  AS  I TP+++   L+ 
Sbjct: 1034 GALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIIN-ASKAISTPIITAQ-LDK 1091

Query: 1272 KKALKRVKSLKKQLTRVCLGEVLQKID 1298
                   + +K ++ +  LGE+ + I+
Sbjct: 1092 DDDADYARLVKGRIEKTLLGEISEYIE 1118



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 50/165 (30%), Positives = 83/165 (50%), Gaps = 3/165 (1%)

Query: 1552 VIYATKGITRCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANT 1611
            V+     ++R +++    +  EK  +L  EG NL  +     V   R   SN+ + +  T
Sbjct: 1200 VVQGIPEVSRAVIHIDEQSGKEKYKLL-VEGDNLRAVMATHGVKGTRTT-SNNTYEVEKT 1257

Query: 1612 YGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGI-RSNSSPLQ 1670
             GIEAA   I  EI+     +G+++D RH+ L++D M ++G    + RFG+ +   S L 
Sbjct: 1258 LGIEAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLM 1317

Query: 1671 QMTFETSFQFLKQATMLGSHDELRSPSACLVVGKVVRGGTGLFEL 1715
              +FE +   L  A   G  D +   S C+++G  +  GTGLF+L
Sbjct: 1318 LASFEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKL 1362



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 27/100 (27%), Positives = 54/100 (54%), Gaps = 2/100 (2%)

Query: 10  RRLQGISFGMYSAEELKKLS-VKSITNPRYL-DSLGNPSANGLYDLALGPADSKEVCSTC 67
           +++  I FGM S EE+++ + ++ ++   Y  D+   P   G+ D  +G ++    C TC
Sbjct: 13  KKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRMGTSEKDRPCETC 72

Query: 68  VQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNC 107
            ++ ++C GH G+I+L L  ++   F  +  +L+  C  C
Sbjct: 73  GKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTC 112


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 40/97 (41%), Positives = 51/97 (52%), Gaps = 10/97 (10%)

Query: 1382 ELGRSRGEQEGDE---EEEGHIVDAEAEE--GDADASDAKRKEKQEEEVDYESEEEEERE 1436
            E G  +GE+EG+E   EEEG   + E EE  G+ +  +    E +EEE + E EEE E E
Sbjct: 852  EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE 911

Query: 1437 GEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEED 1473
            GEE + E   EE     EG     E +EE G G  ED
Sbjct: 912  GEEEEGEGKGEEEGEEGEG-----EGEEEEGEGEGED 943



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 9/98 (9%)

Query: 1378 DNAGELGRSRGEQEGDE----EEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEE 1433
            +  GE G   GE+E  E    EEEG     E  EG+ +  + + +E++E EV+ E E EE
Sbjct: 971  EGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG-EGEGEEEEEGEVEGEVEGEE 1029

Query: 1434 -EREGEENDDEDMQEERNPHREG---ARKTQEQDEEVG 1467
             E EGEE + E+  EER    EG    R  +E++EE G
Sbjct: 1030 GEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEG 1067



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 34/87 (39%), Positives = 46/87 (52%), Gaps = 7/87 (8%)

Query: 1382 ELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEE-EREGEEN 1440
            E G   GE+EG+ EEEG     E EEG+ +       E + EE + E EEEE E EGEE 
Sbjct: 993  EEGEEEGEEEGEGEEEGEGEGEEEEEGEVEG------EVEGEEGEGEGEEEEGEEEGEER 1046

Query: 1441 DDEDMQEERNPHREGARKTQEQDEEVG 1467
            + E   EE   +RE   + + + +E G
Sbjct: 1047 EKEGEGEENRRNREEEEEEEGKYQETG 1073



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 33/101 (32%), Positives = 52/101 (51%), Gaps = 4/101 (3%)

Query: 1374 QRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESE-EE 1432
            Q++ +   +  R++  +EG EEE G   + E EEGD +  + K  E +EE    E E E 
Sbjct: 712  QKEREQGHQKERNQEMEEGGEEEHG---EGEEEEGDREEEEEKEGEGKEEGEGEEVEGER 768

Query: 1433 EEREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEED 1473
            E+ EGE   +E   +E     EG +   E++E  G G E++
Sbjct: 769  EKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKE 809



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 39/99 (39%), Positives = 53/99 (53%), Gaps = 13/99 (13%)

Query: 1382 ELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEE-EREGEE- 1439
            E G  +GE+EG+E E     + E EEG+ +  D +  E +EEE ++E EEEE E EGEE 
Sbjct: 915  EEGEGKGEEEGEEGEG----EGEEEEGEGEGEDGEG-EGEEEEGEWEGEEEEGEGEGEEE 969

Query: 1440 -----NDDEDMQEERNPHREGARKT-QEQDEEVGLGTEE 1472
                  + E   EE     EG  +  +E+ EE G G EE
Sbjct: 970  GEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)

Query: 1378 DNAGELGRSRGEQE-GDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEERE 1436
            +  GE G   GE+E G+ E E    + E EEG+ +  + + + + EEE + E  EE E E
Sbjct: 922  EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG-EEGEGE 980

Query: 1437 GEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEED 1473
            GEE + E   EE     EG  + + ++E  G G EE+
Sbjct: 981  GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 36/87 (41%), Positives = 50/87 (57%), Gaps = 13/87 (14%)

Query: 1384 GRSRGEQEGDEEEEGHIV-DAEAEEGDADASDAKRKEKQEEEVDYESEE-EEEREGEEN- 1440
            G   GE EG+EEEEG +  + E EEG+         E +EEE + E EE E+E EGEEN 
Sbjct: 1005 GEEEGEGEGEEEEEGEVEGEVEGEEGEG--------EGEEEEGEEEGEEREKEGEGEENR 1056

Query: 1441 -DDEDMQEERNPHRE-GARKTQEQDEE 1465
             + E+ +EE   ++E G  + + QD E
Sbjct: 1057 RNREEEEEEEGKYQETGEEENERQDGE 1083



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 2/92 (2%)

Query: 1382 ELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEEND 1441
            E G   GE+EG+ E E    + E EEG+ +  + + +E+ EEE   E EEE E EGEE +
Sbjct: 960  EEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEG--EGEEEGEGEGEEEE 1017

Query: 1442 DEDMQEERNPHREGARKTQEQDEEVGLGTEED 1473
            + +++ E           +E+ EE G   E++
Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE 1049



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 36/100 (36%), Positives = 51/100 (51%), Gaps = 8/100 (8%)

Query: 1378 DNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEE-EERE 1436
            +  GE     GE EG+EE EG   + E EEG+ +  +    E +EEE + + EEE EE E
Sbjct: 873  EGEGEGEEEEGEGEGEEEGEG---EGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGE 929

Query: 1437 GEENDDEDMQEERNPHREGARK----TQEQDEEVGLGTEE 1472
            GE  ++E   E  +   EG  +      E++E  G G EE
Sbjct: 930  GEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEE 969



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 6/90 (6%)

Query: 1385 RSRGEQEGDEEEEGHIVDA--EAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDD 1442
            R   EQE  E E+GH  +   E EEG     + +  E +EEE D E EEE+E EG+E  +
Sbjct: 705  RDGEEQEQKEREQGHQKERNQEMEEG----GEEEHGEGEEEEGDREEEEEKEGEGKEEGE 760

Query: 1443 EDMQEERNPHREGARKTQEQDEEVGLGTEE 1472
             +  E      EG RK +E+  +   G EE
Sbjct: 761  GEEVEGEREKEEGERKKEERAGKEEKGEEE 790



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 34/98 (34%), Positives = 49/98 (50%), Gaps = 5/98 (5%)

Query: 1381 GELGRSRGEQEGDEEE-EGHIVDAEAEE----GDADASDAKRKEKQEEEVDYESEEEEER 1435
            GE+   +GE+E +EEE EG   + E EE    G+ +  + K +E+ EE    E  EE E 
Sbjct: 817  GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEG 876

Query: 1436 EGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEED 1473
            EGEE + E   EE         + + + EE G G  E+
Sbjct: 877  EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEE 914



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 38/103 (36%), Positives = 52/103 (50%), Gaps = 14/103 (13%)

Query: 1378 DNAGELGRSRGEQEGDE-------EEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESE 1430
            D  GE     GE EG+E       EEEG   + E EEG+ +  + + + + EEE + E E
Sbjct: 943  DGEGEGEEEEGEWEGEEEEGEGEGEEEG---EGEGEEGEGEGEEEEGEGEGEEE-EGEEE 998

Query: 1431 EEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEED 1473
             EEE EGEE  + + +EE     EG     E +E  G G EE+
Sbjct: 999  GEEEGEGEEEGEGEGEEEEEGEVEG---EVEGEEGEGEGEEEE 1038



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 18/126 (14%)

Query: 1365 RNVNTRRATQRDLDNAGELGRSRGEQE-GDEEEEGHIVDAEAEEGDADASDAKRKEKQEE 1423
            R    ++   ++++  GE     GE+E GD EEE        EEG+ +  + +R EK+E 
Sbjct: 715  REQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGER-EKEEG 773

Query: 1424 EVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQ----------------EQDEEVG 1467
            E   E    +E +GEE  D+   EE      G  K +                E++EE G
Sbjct: 774  ERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG 833

Query: 1468 LGTEED 1473
             G EE+
Sbjct: 834  EGEEEE 839



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 42/138 (30%), Positives = 64/138 (46%), Gaps = 16/138 (11%)

Query: 1352 ESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQ---EGDEEEEGHIVDA-EAEE 1407
            E ++ +  K    R    R   +   +  G+ G    E+    G+E+EEG  V+  E EE
Sbjct: 762  EEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEE 821

Query: 1408 GDADASDAKRK-EKQEEEVDYESEE----EEERE--GEENDDEDMQEERNPHREGARKTQ 1460
            G  +  + + + E +EEE + E EE    EEE E  GEE  +E   EE     EG  + +
Sbjct: 822  GKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEE 881

Query: 1461 E-----QDEEVGLGTEED 1473
            E     ++E  G G EE+
Sbjct: 882  EGEGEGEEEGEGEGEEEE 899



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 40/116 (34%), Positives = 55/116 (47%), Gaps = 20/116 (17%)

Query: 1378 DNAGELGRSRGEQEGDEEE-EGHIVDAEAEE------GDADASDAKRKEK--------QE 1422
            +  GE      E EG+EEE EG   + E EE      G+ +  + + +E+        +E
Sbjct: 821  EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE 880

Query: 1423 EEVDYESEEEEEREGEENDDEDMQEE----RNPHREGARKTQEQDEE-VGLGTEED 1473
            EE + E EEE E EGEE + E   EE         EG  K +E+ EE  G G EE+
Sbjct: 881  EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 13/101 (12%)

Query: 1378 DNAGELGRSRGEQEGDEEE-EGHIVDAEAE--------EGDADASDAKRKEKQE---EEV 1425
            +  GE     GE EG+EEE EG   D E E        EG+ +  + + +E+ E   EE 
Sbjct: 918  EGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEG 977

Query: 1426 DYESEEEE-EREGEENDDEDMQEERNPHREGARKTQEQDEE 1465
            + E EEEE E EGEE + E+  EE     E      E++EE
Sbjct: 978  EGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 1/97 (1%)

Query: 1378 DNAGELGRSRGEQEGDEEE-EGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEERE 1436
            +  GE     GE EG+EEE EG   + E EE   +  + + + + E E + E E E E E
Sbjct: 967  EEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVE 1026

Query: 1437 GEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEED 1473
            GEE + E  +EE     E   K  E +E      EE+
Sbjct: 1027 GEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEE 1063



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 4/101 (3%)

Query: 1381 GELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEEN 1440
            GE+    GE EG+EEE     +   +EG+ + +   R+E++EEE  Y+   EEE E ++ 
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDG 1082

Query: 1441 DD-EDMQEERNPHREGARKTQEQDEEV---GLGTEEDPSLP 1477
            ++ + + + +   + G  KT ++       G G E+   +P
Sbjct: 1083 EEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMP 1123



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 19/133 (14%)

Query: 1381 GELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDY-ESEEEEEREGEE 1439
            G  GR  G  E       H  D E E+G+ D    + +   E E +  E EE ++R+GEE
Sbjct: 650  GPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEE 709

Query: 1440 NDDEDM----QEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGP 1495
             + ++     Q+ERN   E     +  +EE G G EE+          R+    +E +G 
Sbjct: 710  QEQKEREQGHQKERNQEME-----EGGEEEHGEGEEEEGD--------REEEEEKEGEGK 756

Query: 1496 EAME-RRVQAVRE 1507
            E  E   V+  RE
Sbjct: 757  EEGEGEEVEGERE 769



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 8/103 (7%)

Query: 1378 DNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREG 1437
            D   E G S  E   DEE E    D    E +      K   ++EE    + EE+E++E 
Sbjct: 656  DGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKER 715

Query: 1438 EENDDEDMQEE-----RNPHREGARK---TQEQDEEVGLGTEE 1472
            E+   ++  +E        H EG  +    +E++E+ G G EE
Sbjct: 716  EQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEE 758



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 30/120 (25%), Positives = 50/120 (41%), Gaps = 6/120 (5%)

Query: 1389 EQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEE 1448
            E E  EE+EG      AE+   +  + +  E  EE V      +E+ E   +D  D  E 
Sbjct: 583  EVEIPEEKEG------AEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEV 636

Query: 1449 RNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREI 1508
                 +   + ++  E  G GT E+ S  A   Q  +    ++ +G   MER  +  +E+
Sbjct: 637  SEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKEL 696



 Score = 32.3 bits (72), Expect = 4.1
 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 3/78 (3%)

Query: 1374 QRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGD-ADASDAKRKEKQEEEVDYESEEE 1432
            +R+ +  GE  R   E+E  EEEEG   +   EE +  D  + K+  K +  V Y   + 
Sbjct: 1045 EREKEGEGEENRRNREEE--EEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKT 1102

Query: 1433 EEREGEENDDEDMQEERN 1450
             +++   N   + +E+R+
Sbjct: 1103 YQKKSVTNTQGNGKEQRS 1120


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 41/120 (34%), Positives = 55/120 (45%), Gaps = 6/120 (5%)

Query: 1383 LGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDD 1442
            +  S  E+E +EEEE    + E EE D +  +   +E  EEE + E E EEE E EE + 
Sbjct: 883  INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942

Query: 1443 EDMQEERNPHREGARKTQEQDE------EVGLGTEEDPSLPALLTQPRKPTHSQEPQGPE 1496
            E+ +EE +   E   +  E  E      EV  G    P+LP  L  P  P   Q    PE
Sbjct: 943  EEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPE 1002



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 20/102 (19%), Positives = 42/102 (41%), Gaps = 1/102 (0%)

Query: 1407 EGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEV 1466
            EG          E+    ++  S +EEE E EE ++E+ +EE     +   + ++++E  
Sbjct: 863  EGTPGGGGPPALEEDLTVININSSDEEEEE-EEEEEEEEEEEEEEEEDFEEEEEDEEEYF 921

Query: 1467 GLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREI 1508
                EE+        +       +E +  E  E  ++ V ++
Sbjct: 922  EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL 963


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 123

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 34/114 (29%), Positives = 58/114 (50%), Gaps = 6/114 (5%)

Query: 1355 KKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEA---EEGDAD 1411
            KKK  K            T+ + +  G+    R E+  ++E++    + E    +E +  
Sbjct: 1    KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 1412 ASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEE 1465
                KRK+K+EEE   E EEEEE E EE ++E+ +E R   ++  R+ +E++EE
Sbjct: 61   KRKRKRKKKKEEE---EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 24/117 (20%), Positives = 61/117 (52%), Gaps = 1/117 (0%)

Query: 1385 RSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDED 1444
            + + ++E +E EE    + E EE +    + ++++++E+E   +++E E+R+ +E +++ 
Sbjct: 3    KKKKKKETEETEETEETEEE-EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61

Query: 1445 MQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERR 1501
             + +R   +E   + +E++EE     EE+        + +K    +E +  +   RR
Sbjct: 62   RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 18/85 (21%), Positives = 39/85 (45%)

Query: 1352 ESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDAD 1411
            E  K+K  K         +   + +     +  + + E+E +EEEE    + E EE +  
Sbjct: 35   EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEG 94

Query: 1412 ASDAKRKEKQEEEVDYESEEEEERE 1436
                K+K+++ +E + E +++  R+
Sbjct: 95   RRRKKKKKRRRKEEEEEKKKKRRRK 119



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 16/107 (14%), Positives = 49/107 (45%)

Query: 1352 ESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDAD 1411
            E  +++  K    +     +  +++     +    R E+E +E++       + EE + +
Sbjct: 17   EETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEERE 76

Query: 1412 ASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARK 1458
              + + +E++EEE   E    ++++     +E+ ++++   R+  +K
Sbjct: 77   EEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 10/114 (8%)

Query: 1362 SAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDA----------D 1411
            S    V ++ A  +D    GE  + R   +G         +A  + G+            
Sbjct: 370  SRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPS 429

Query: 1412 ASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEE 1465
            AS A+  ++ +EE D E EEEEE E EE  D + +E+    +EG    +E+DEE
Sbjct: 430  ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEE 483



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 18/135 (13%)

Query: 1389 EQEGDEEEEGHIVDAEAEEGDA-DASDAKRKEKQEEEVDYESEEEEEREGEENDDEDM-- 1445
            ++E DEEEE    + E E  D+ +  D ++ ++ +E+ + E EEEE   G++ D   M  
Sbjct: 440  DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 499

Query: 1446 ---QEERN--PHREGARKTQEQDEEVGLGT----EEDPSLPALL------TQPRKPTHSQ 1490
                 E+N  P ++ +R + EQ  +  + +     E+P  P+ +       QP + T  +
Sbjct: 500  LQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEE 559

Query: 1491 EPQGPEAMERRVQAV 1505
            E    +  E  ++A+
Sbjct: 560  ESPVSQLFELEIEAL 574



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 19/52 (36%), Positives = 35/52 (67%), Gaps = 6/52 (11%)

Query: 1403 AEAEEGDADASDAKRKEKQEEEVDYESEEEEE------REGEENDDEDMQEE 1448
            AE ++ D + SD + +E++EEE +  ++ EEE      +EG+E+D+E+ +EE
Sbjct: 433  AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEE 484


>gi|215422388 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 10/114 (8%)

Query: 1362 SAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDA----------D 1411
            S    V ++ A  +D    GE  + R   +G         +A  + G+            
Sbjct: 370  SRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPS 429

Query: 1412 ASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEE 1465
            AS A+  ++ +EE D E EEEEE E EE  D + +E+    +EG    +E+DEE
Sbjct: 430  ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEE 483



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 18/135 (13%)

Query: 1389 EQEGDEEEEGHIVDAEAEEGDA-DASDAKRKEKQEEEVDYESEEEEEREGEENDDEDM-- 1445
            ++E DEEEE    + E E  D+ +  D ++ ++ +E+ + E EEEE   G++ D   M  
Sbjct: 440  DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 499

Query: 1446 ---QEERN--PHREGARKTQEQDEEVGLGT----EEDPSLPALL------TQPRKPTHSQ 1490
                 E+N  P ++ +R + EQ  +  + +     E+P  P+ +       QP + T  +
Sbjct: 500  LQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEE 559

Query: 1491 EPQGPEAMERRVQAV 1505
            E    +  E  ++A+
Sbjct: 560  ESPVSQLFELEIEAL 574



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 19/52 (36%), Positives = 35/52 (67%), Gaps = 6/52 (11%)

Query: 1403 AEAEEGDADASDAKRKEKQEEEVDYESEEEEE------REGEENDDEDMQEE 1448
            AE ++ D + SD + +E++EEE +  ++ EEE      +EG+E+D+E+ +EE
Sbjct: 433  AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEE 484


>gi|215422366 death-domain associated protein isoform b [Homo sapiens]
          Length = 752

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 10/114 (8%)

Query: 1362 SAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDA----------D 1411
            S    V ++ A  +D    GE  + R   +G         +A  + G+            
Sbjct: 382  SRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPS 441

Query: 1412 ASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEE 1465
            AS A+  ++ +EE D E EEEEE E EE  D + +E+    +EG    +E+DEE
Sbjct: 442  ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEE 495



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 18/135 (13%)

Query: 1389 EQEGDEEEEGHIVDAEAEEGDA-DASDAKRKEKQEEEVDYESEEEEEREGEENDDEDM-- 1445
            ++E DEEEE    + E E  D+ +  D ++ ++ +E+ + E EEEE   G++ D   M  
Sbjct: 452  DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSS 511

Query: 1446 ---QEERN--PHREGARKTQEQDEEVGLGT----EEDPSLPALL------TQPRKPTHSQ 1490
                 E+N  P ++ +R + EQ  +  + +     E+P  P+ +       QP + T  +
Sbjct: 512  LQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEE 571

Query: 1491 EPQGPEAMERRVQAV 1505
            E    +  E  ++A+
Sbjct: 572  ESPVSQLFELEIEAL 586



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 19/52 (36%), Positives = 35/52 (67%), Gaps = 6/52 (11%)

Query: 1403 AEAEEGDADASDAKRKEKQEEEVDYESEEEEE------REGEENDDEDMQEE 1448
            AE ++ D + SD + +E++EEE +  ++ EEE      +EG+E+D+E+ +EE
Sbjct: 445  AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEE 496


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 17/122 (13%)

Query: 1368 NTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDY 1427
            ++ R T     ++ E G    E+E +EEEE    + E    +    + + +E++EEE   
Sbjct: 259  DSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEEEEEEEEEETGS 314

Query: 1428 ESEEEEEREGEENDDEDMQEERNPHREG-------------ARKTQEQDEEVGLGTEEDP 1474
             SEE  E+  EE  +E+M E+     E              + +++E +EEVG GT +  
Sbjct: 315  NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 374

Query: 1475 SL 1476
            +L
Sbjct: 375  AL 376



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 44/167 (26%), Positives = 70/167 (41%), Gaps = 16/167 (9%)

Query: 1382 ELGRSRGEQEGDEEEEGHIV-------DAEAEEGDADASDAKRKEKQEEEVDYESEEEEE 1434
            ELG  R   + ++ EE  ++       D+E +   A++S A+     EEE + E EEEEE
Sbjct: 232  ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 291

Query: 1435 ----REGEENDDEDMQEER----NPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKP 1486
                 E EE ++E+ +EE     N      +  +E  EE     EE  +   LL  P   
Sbjct: 292  GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESR 351

Query: 1487 THSQEPQGPEAMERRVQAVREIHPFID-DYQYDTEESLWCQVTVKLP 1532
                  +  EA E   +   +     + DY  D+   L  ++  +LP
Sbjct: 352  FDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELP 398



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 44/204 (21%), Positives = 78/204 (38%), Gaps = 26/204 (12%)

Query: 1355 KKKNNKASAFRNVNTR-RATQRDLDNAGELG--------------RSRGEQEGDEEEEGH 1399
            K++  KA   R  N+  R ++RD    GEL               R    ++  EE++  
Sbjct: 24   KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSL 83

Query: 1400 IVDAEAEEGDADASDAKRKEKQEEE-----VDYESEEEEEREGEENDDEDMQEERNPHRE 1454
             +    +    +    ++ EK++E+     V     E  +R  EE D    + ER   RE
Sbjct: 84   AIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRRE 143

Query: 1455 GARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRV--QAVREI---- 1508
             AR+   ++ +     E        + + +K    Q+ +   A ERR   +A RE+    
Sbjct: 144  MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 203

Query: 1509 HPFIDDYQYDTEESLWCQVTVKLP 1532
                +DY    + S W +   + P
Sbjct: 204  RTMREDYSDKVKASHWSRSPPRPP 227


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 17/122 (13%)

Query: 1368 NTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDY 1427
            ++ R T     ++ E G    E+E +EEEE    + E    +    + + +E++EEE   
Sbjct: 269  DSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEEEEEEEEEETGS 324

Query: 1428 ESEEEEEREGEENDDEDMQEERNPHREG-------------ARKTQEQDEEVGLGTEEDP 1474
             SEE  E+  EE  +E+M E+     E              + +++E +EEVG GT +  
Sbjct: 325  NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 384

Query: 1475 SL 1476
            +L
Sbjct: 385  AL 386



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 44/167 (26%), Positives = 70/167 (41%), Gaps = 16/167 (9%)

Query: 1382 ELGRSRGEQEGDEEEEGHIV-------DAEAEEGDADASDAKRKEKQEEEVDYESEEEEE 1434
            ELG  R   + ++ EE  ++       D+E +   A++S A+     EEE + E EEEEE
Sbjct: 242  ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 301

Query: 1435 ----REGEENDDEDMQEER----NPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKP 1486
                 E EE ++E+ +EE     N      +  +E  EE     EE  +   LL  P   
Sbjct: 302  GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESR 361

Query: 1487 THSQEPQGPEAMERRVQAVREIHPFID-DYQYDTEESLWCQVTVKLP 1532
                  +  EA E   +   +     + DY  D+   L  ++  +LP
Sbjct: 362  FDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELP 408


>gi|115529449 upstream binding transcription factor, RNA polymerase I
            isoform b [Homo sapiens]
          Length = 727

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 72/395 (18%), Positives = 141/395 (35%), Gaps = 81/395 (20%)

Query: 1093 SQKIQEAVKALKLESENRN----------GRSPGTQEMLRMWYELDEESRRKYQKKAAAC 1142
            S+K +  V A+ + SE +             S  T+ + RMW +L E+ + KY+ + AA 
Sbjct: 367  SEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAL 426

Query: 1143 ---------------------PDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKS 1181
                                 P  +  +W+  +            + DY   +     K+
Sbjct: 427  KAQSERKPGGEREERGKLPESPKRAEEIWQQSV------------IGDYLARFKNDRVKA 474

Query: 1182 YEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNV 1241
             +  E++ + +    +L W +   E  +      ++    P+   +     F G  +   
Sbjct: 475  LKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 534

Query: 1242 TLGIPRLREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQE 1301
              G  +  + L+        P+    V    +  +  +S K+   ++             
Sbjct: 535  MNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLA------------ 582

Query: 1302 SFCMEEKQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKA 1361
                EE+Q +++V+   +           K L P+D   + E          I  K    
Sbjct: 583  ----EEQQKQYKVHLDLWV----------KSLSPQDRAAYKEY---------ISNKRKSM 619

Query: 1362 SAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQ 1421
            +  R  N + +++  L +  E      E E DE+E+    D E  +   D  D+     +
Sbjct: 620  TKLRGPNPK-SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 678

Query: 1422 EEEVDYESEEEEEREGEENDDEDMQEERNPHREGA 1456
            +E  D   +E EE + +E+DDED  E+ +   EG+
Sbjct: 679  DESED--GDENEEDDEDEDDDEDDDEDEDNESEGS 711



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 1417 RKEKQEEEVDYESEEEEEREGEENDDE--DMQEERNPHREGARKTQEQDEEVGLGTEED 1473
            + + + EE D E E++E+ + EE DDE  D  E+     E + + + +D +     +ED
Sbjct: 635  QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693


>gi|115529451 upstream binding transcription factor, RNA polymerase I
            isoform b [Homo sapiens]
          Length = 727

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 72/395 (18%), Positives = 141/395 (35%), Gaps = 81/395 (20%)

Query: 1093 SQKIQEAVKALKLESENRN----------GRSPGTQEMLRMWYELDEESRRKYQKKAAAC 1142
            S+K +  V A+ + SE +             S  T+ + RMW +L E+ + KY+ + AA 
Sbjct: 367  SEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAL 426

Query: 1143 ---------------------PDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKS 1181
                                 P  +  +W+  +            + DY   +     K+
Sbjct: 427  KAQSERKPGGEREERGKLPESPKRAEEIWQQSV------------IGDYLARFKNDRVKA 474

Query: 1182 YEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNV 1241
             +  E++ + +    +L W +   E  +      ++    P+   +     F G  +   
Sbjct: 475  LKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 534

Query: 1242 TLGIPRLREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQE 1301
              G  +  + L+        P+    V    +  +  +S K+   ++             
Sbjct: 535  MNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLA------------ 582

Query: 1302 SFCMEEKQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKA 1361
                EE+Q +++V+   +           K L P+D   + E          I  K    
Sbjct: 583  ----EEQQKQYKVHLDLWV----------KSLSPQDRAAYKEY---------ISNKRKSM 619

Query: 1362 SAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQ 1421
            +  R  N + +++  L +  E      E E DE+E+    D E  +   D  D+     +
Sbjct: 620  TKLRGPNPK-SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 678

Query: 1422 EEEVDYESEEEEEREGEENDDEDMQEERNPHREGA 1456
            +E  D   +E EE + +E+DDED  E+ +   EG+
Sbjct: 679  DESED--GDENEEDDEDEDDDEDDDEDEDNESEGS 711



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 1417 RKEKQEEEVDYESEEEEEREGEENDDE--DMQEERNPHREGARKTQEQDEEVGLGTEED 1473
            + + + EE D E E++E+ + EE DDE  D  E+     E + + + +D +     +ED
Sbjct: 635  QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693


>gi|7657671 upstream binding transcription factor, RNA polymerase I
            isoform a [Homo sapiens]
          Length = 764

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 72/395 (18%), Positives = 141/395 (35%), Gaps = 81/395 (20%)

Query: 1093 SQKIQEAVKALKLESENRN----------GRSPGTQEMLRMWYELDEESRRKYQKKAAAC 1142
            S+K +  V A+ + SE +             S  T+ + RMW +L E+ + KY+ + AA 
Sbjct: 404  SEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAL 463

Query: 1143 ---------------------PDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKS 1181
                                 P  +  +W+  +            + DY   +     K+
Sbjct: 464  KAQSERKPGGEREERGKLPESPKRAEEIWQQSV------------IGDYLARFKNDRVKA 511

Query: 1182 YEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNV 1241
             +  E++ + +    +L W +   E  +      ++    P+   +     F G  +   
Sbjct: 512  LKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPP 571

Query: 1242 TLGIPRLREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQE 1301
              G  +  + L+        P+    V    +  +  +S K+   ++             
Sbjct: 572  MNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLA------------ 619

Query: 1302 SFCMEEKQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKA 1361
                EE+Q +++V+   +           K L P+D   + E          I  K    
Sbjct: 620  ----EEQQKQYKVHLDLWV----------KSLSPQDRAAYKEY---------ISNKRKSM 656

Query: 1362 SAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQ 1421
            +  R  N + +++  L +  E      E E DE+E+    D E  +   D  D+     +
Sbjct: 657  TKLRGPNPK-SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 715

Query: 1422 EEEVDYESEEEEEREGEENDDEDMQEERNPHREGA 1456
            +E  D   +E EE + +E+DDED  E+ +   EG+
Sbjct: 716  DESED--GDENEEDDEDEDDDEDDDEDEDNESEGS 748



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 1417 RKEKQEEEVDYESEEEEEREGEENDDE--DMQEERNPHREGARKTQEQDEEVGLGTEED 1473
            + + + EE D E E++E+ + EE DDE  D  E+     E + + + +D +     +ED
Sbjct: 672  QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 730


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9
            [Homo sapiens]
          Length = 771

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 17/122 (13%)

Query: 1368 NTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDY 1427
            ++ R T     ++ E G    E+E +EEEE    + E    +    + + +E++EEE   
Sbjct: 260  DSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEEEEEEEEEETGS 315

Query: 1428 ESEEEEEREGEENDDEDMQEERNPHREG-------------ARKTQEQDEEVGLGTEEDP 1474
             SEE  E+  EE  +E+M E+     E              + +++E +EEVG GT +  
Sbjct: 316  NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 375

Query: 1475 SL 1476
            +L
Sbjct: 376  AL 377



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 7/91 (7%)

Query: 1382 ELGRSRGEQEGDEEEEGHIV-------DAEAEEGDADASDAKRKEKQEEEVDYESEEEEE 1434
            ELG  R   + ++ EE  ++       D+E +   A++S A+     EEE + E EEEEE
Sbjct: 233  ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 292

Query: 1435 REGEENDDEDMQEERNPHREGARKTQEQDEE 1465
                E  +E+ +EE     E    ++E  E+
Sbjct: 293  GSTSEESEEEEEEEEEEEEETGSNSEEASEQ 323



 Score = 38.1 bits (87), Expect = 0.074
 Identities = 52/205 (25%), Positives = 80/205 (39%), Gaps = 27/205 (13%)

Query: 1355 KKKNNKASAFRNVNTR-RATQRDLDNAGELG---------RSRGEQEGDEEEEGHIVDAE 1404
            K++  KA   R  N+  R ++RD    GEL           S   +E   E+ G   D+ 
Sbjct: 24   KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSL 83

Query: 1405 AEEGDADAS---------DAKRKEKQEEEVDYESEEEE--EREGEENDDEDMQEERNPHR 1453
            A +     S         D KRKEK+   V  +  E E  +R  EE D    + ER   R
Sbjct: 84   AIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRR 143

Query: 1454 EGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRV--QAVREI--- 1508
            E AR+   ++ +     E        + + +K    Q+ +   A ERR   +A RE+   
Sbjct: 144  EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH 203

Query: 1509 -HPFIDDYQYDTEESLWCQVTVKLP 1532
                 +DY    + S W +   + P
Sbjct: 204  HRTMREDYSDKVKASHWSRSPPRPP 228



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 40/138 (28%), Positives = 58/138 (42%), Gaps = 27/138 (19%)

Query: 1355 KKKNNKASAFRNVNTRRATQR----DLDNAGELGRS--RGEQEGDEEEEGH--IVDAEAE 1406
            +++  +  A R V+    T R    D   A    RS  R  +E  E  +G   + + + E
Sbjct: 188  EERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME 247

Query: 1407 EGDA-----DASDAKRKEKQEEEVDYES----EEEEEREGEENDDEDMQEERNPHREGAR 1457
            E D      D SD++RK    E    ES    EEEEE E EE ++    EE         
Sbjct: 248  ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE--------- 298

Query: 1458 KTQEQDEEVGLGTEEDPS 1475
             ++E++EE     EE  S
Sbjct: 299  -SEEEEEEEEEEEEETGS 315


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8
            [Homo sapiens]
          Length = 780

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 17/122 (13%)

Query: 1368 NTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDY 1427
            ++ R T     ++ E G    E+E +EEEE    + E    +    + + +E++EEE   
Sbjct: 269  DSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEEEEEEEEEETGS 324

Query: 1428 ESEEEEEREGEENDDEDMQEERNPHREG-------------ARKTQEQDEEVGLGTEEDP 1474
             SEE  E+  EE  +E+M E+     E              + +++E +EEVG GT +  
Sbjct: 325  NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 384

Query: 1475 SL 1476
            +L
Sbjct: 385  AL 386



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 7/91 (7%)

Query: 1382 ELGRSRGEQEGDEEEEGHIV-------DAEAEEGDADASDAKRKEKQEEEVDYESEEEEE 1434
            ELG  R   + ++ EE  ++       D+E +   A++S A+     EEE + E EEEEE
Sbjct: 242  ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 301

Query: 1435 REGEENDDEDMQEERNPHREGARKTQEQDEE 1465
                E  +E+ +EE     E    ++E  E+
Sbjct: 302  GSTSEESEEEEEEEEEEEEETGSNSEEASEQ 332



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 40/138 (28%), Positives = 58/138 (42%), Gaps = 27/138 (19%)

Query: 1355 KKKNNKASAFRNVNTRRATQR----DLDNAGELGRS--RGEQEGDEEEEGH--IVDAEAE 1406
            +++  +  A R V+    T R    D   A    RS  R  +E  E  +G   + + + E
Sbjct: 197  EERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME 256

Query: 1407 EGDA-----DASDAKRKEKQEEEVDYES----EEEEEREGEENDDEDMQEERNPHREGAR 1457
            E D      D SD++RK    E    ES    EEEEE E EE ++    EE         
Sbjct: 257  ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE--------- 307

Query: 1458 KTQEQDEEVGLGTEEDPS 1475
             ++E++EE     EE  S
Sbjct: 308  -SEEEEEEEEEEEEETGS 324



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 56/214 (26%), Positives = 83/214 (38%), Gaps = 36/214 (16%)

Query: 1355 KKKNNKASAFRNVNTR-RATQRDLDNAGELG---------RSRGEQEGDEEEEGHIVDAE 1404
            K++  KA   R  N+  R ++RD    GEL           S   +E   E+ G   D+ 
Sbjct: 24   KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSL 83

Query: 1405 AEEGDADAS---------DAKRKEKQEEEVDYESEEEE--EREGEENDDEDMQEERNPHR 1453
            A +     S         D KRKEK+   V  +  E E  +R  EE D    + ER   R
Sbjct: 84   AIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRR 143

Query: 1454 EGAR---KTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPE------AMERRV-- 1502
            E AR   + +  ++ V L  +    L     + RK    Q+ Q  +      A ERR   
Sbjct: 144  EMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER 203

Query: 1503 QAVREI----HPFIDDYQYDTEESLWCQVTVKLP 1532
            +A RE+        +DY    + S W +   + P
Sbjct: 204  EARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 237


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5
            [Homo sapiens]
          Length = 748

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 17/122 (13%)

Query: 1368 NTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDY 1427
            ++ R T     ++ E G    E+E +EEEE    + E    +    + + +E++EEE   
Sbjct: 237  DSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEEEEEEEEEETGS 292

Query: 1428 ESEEEEEREGEENDDEDMQEERNPHREG-------------ARKTQEQDEEVGLGTEEDP 1474
             SEE  E+  EE  +E+M E+     E              + +++E +EEVG GT +  
Sbjct: 293  NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 352

Query: 1475 SL 1476
            +L
Sbjct: 353  AL 354



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 7/91 (7%)

Query: 1382 ELGRSRGEQEGDEEEEGHIV-------DAEAEEGDADASDAKRKEKQEEEVDYESEEEEE 1434
            ELG  R   + ++ EE  ++       D+E +   A++S A+     EEE + E EEEEE
Sbjct: 210  ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 269

Query: 1435 REGEENDDEDMQEERNPHREGARKTQEQDEE 1465
                E  +E+ +EE     E    ++E  E+
Sbjct: 270  GSTSEESEEEEEEEEEEEEETGSNSEEASEQ 300



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 40/138 (28%), Positives = 58/138 (42%), Gaps = 27/138 (19%)

Query: 1355 KKKNNKASAFRNVNTRRATQR----DLDNAGELGRS--RGEQEGDEEEEGH--IVDAEAE 1406
            +++  +  A R V+    T R    D   A    RS  R  +E  E  +G   + + + E
Sbjct: 165  EERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME 224

Query: 1407 EGDA-----DASDAKRKEKQEEEVDYES----EEEEEREGEENDDEDMQEERNPHREGAR 1457
            E D      D SD++RK    E    ES    EEEEE E EE ++    EE         
Sbjct: 225  ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE--------- 275

Query: 1458 KTQEQDEEVGLGTEEDPS 1475
             ++E++EE     EE  S
Sbjct: 276  -SEEEEEEEEEEEEETGS 292


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4
            [Homo sapiens]
          Length = 737

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 17/122 (13%)

Query: 1368 NTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDY 1427
            ++ R T     ++ E G    E+E +EEEE    + E    +    + + +E++EEE   
Sbjct: 226  DSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEEEEEEEEEETGS 281

Query: 1428 ESEEEEEREGEENDDEDMQEERNPHREG-------------ARKTQEQDEEVGLGTEEDP 1474
             SEE  E+  EE  +E+M E+     E              + +++E +EEVG GT +  
Sbjct: 282  NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 341

Query: 1475 SL 1476
            +L
Sbjct: 342  AL 343



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 7/91 (7%)

Query: 1382 ELGRSRGEQEGDEEEEGHIV-------DAEAEEGDADASDAKRKEKQEEEVDYESEEEEE 1434
            ELG  R   + ++ EE  ++       D+E +   A++S A+     EEE + E EEEEE
Sbjct: 199  ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 258

Query: 1435 REGEENDDEDMQEERNPHREGARKTQEQDEE 1465
                E  +E+ +EE     E    ++E  E+
Sbjct: 259  GSTSEESEEEEEEEEEEEEETGSNSEEASEQ 289



 Score = 38.1 bits (87), Expect = 0.074
 Identities = 48/188 (25%), Positives = 73/188 (38%), Gaps = 26/188 (13%)

Query: 1371 RATQRDLDNAGELGRSRGE---------QEGDEEEEGHIVDAEAEEGDADAS-------- 1413
            R ++RD    GEL   R E         +E   E+ G   D+ A +     S        
Sbjct: 7    RDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHR 66

Query: 1414 -DAKRKEKQEEEVDYESEEEE--EREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGT 1470
             D KRKEK+   V  +  E E  +R  EE D    + ER   RE AR+   ++ +     
Sbjct: 67   KDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 126

Query: 1471 EEDPSLPALLTQPRKPTHSQEPQGPEAMERRV--QAVREI----HPFIDDYQYDTEESLW 1524
            E        + + +K    Q+ +   A ERR   +A RE+        +DY    + S W
Sbjct: 127  ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 186

Query: 1525 CQVTVKLP 1532
             +   + P
Sbjct: 187  SRSPPRPP 194



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 40/138 (28%), Positives = 58/138 (42%), Gaps = 27/138 (19%)

Query: 1355 KKKNNKASAFRNVNTRRATQR----DLDNAGELGRS--RGEQEGDEEEEGH--IVDAEAE 1406
            +++  +  A R V+    T R    D   A    RS  R  +E  E  +G   + + + E
Sbjct: 154  EERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME 213

Query: 1407 EGDA-----DASDAKRKEKQEEEVDYES----EEEEEREGEENDDEDMQEERNPHREGAR 1457
            E D      D SD++RK    E    ES    EEEEE E EE ++    EE         
Sbjct: 214  ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE--------- 264

Query: 1458 KTQEQDEEVGLGTEEDPS 1475
             ++E++EE     EE  S
Sbjct: 265  -SEEEEEEEEEEEEETGS 281


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform 3
            [Homo sapiens]
          Length = 526

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 17/122 (13%)

Query: 1368 NTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDY 1427
            ++ R T     ++ E G    E+E +EEEE    + E    +    + + +E++EEE   
Sbjct: 15   DSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEEEEEEEEEETGS 70

Query: 1428 ESEEEEEREGEENDDEDMQEERNPHREG-------------ARKTQEQDEEVGLGTEEDP 1474
             SEE  E+  EE  +E+M E+     E              + +++E +EEVG GT +  
Sbjct: 71   NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 130

Query: 1475 SL 1476
            +L
Sbjct: 131  AL 132



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 22/66 (33%), Positives = 34/66 (51%)

Query: 1400 IVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKT 1459
            I D+E +   A++S A+     EEE + E EEEEE    E  +E+ +EE     E    +
Sbjct: 13   ISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 72

Query: 1460 QEQDEE 1465
            +E  E+
Sbjct: 73   EEASEQ 78



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 3/55 (5%)

Query: 1411 DASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEE 1465
            D SD++RK    E    ES    E   EE ++E+ +EE     E + + +E++EE
Sbjct: 12   DISDSERKTSSAESSSAESGSGSE---EEEEEEEEEEEEGSTSEESEEEEEEEEE 63


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2
            [Homo sapiens]
          Length = 782

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 17/122 (13%)

Query: 1368 NTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDY 1427
            ++ R T     ++ E G    E+E +EEEE    + E    +    + + +E++EEE   
Sbjct: 271  DSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEEEEEEEEEETGS 326

Query: 1428 ESEEEEEREGEENDDEDMQEERNPHREG-------------ARKTQEQDEEVGLGTEEDP 1474
             SEE  E+  EE  +E+M E+     E              + +++E +EEVG GT +  
Sbjct: 327  NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 386

Query: 1475 SL 1476
            +L
Sbjct: 387  AL 388



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 7/91 (7%)

Query: 1382 ELGRSRGEQEGDEEEEGHIV-------DAEAEEGDADASDAKRKEKQEEEVDYESEEEEE 1434
            ELG  R   + ++ EE  ++       D+E +   A++S A+     EEE + E EEEEE
Sbjct: 244  ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 303

Query: 1435 REGEENDDEDMQEERNPHREGARKTQEQDEE 1465
                E  +E+ +EE     E    ++E  E+
Sbjct: 304  GSTSEESEEEEEEEEEEEEETGSNSEEASEQ 334



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 40/138 (28%), Positives = 58/138 (42%), Gaps = 27/138 (19%)

Query: 1355 KKKNNKASAFRNVNTRRATQR----DLDNAGELGRS--RGEQEGDEEEEGH--IVDAEAE 1406
            +++  +  A R V+    T R    D   A    RS  R  +E  E  +G   + + + E
Sbjct: 199  EERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKME 258

Query: 1407 EGDA-----DASDAKRKEKQEEEVDYES----EEEEEREGEENDDEDMQEERNPHREGAR 1457
            E D      D SD++RK    E    ES    EEEEE E EE ++    EE         
Sbjct: 259  ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE--------- 309

Query: 1458 KTQEQDEEVGLGTEEDPS 1475
             ++E++EE     EE  S
Sbjct: 310  -SEEEEEEEEEEEEETGS 326



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 54/216 (25%), Positives = 80/216 (37%), Gaps = 38/216 (17%)

Query: 1355 KKKNNKASAFRNVNTR-RATQRDLDNAGELGRSRGE---------QEGDEEEEGHIVDAE 1404
            K++  KA   R  N+  R ++RD    GEL   R E         +E   E+ G   D+ 
Sbjct: 24   KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSL 83

Query: 1405 AEEGDADAS---------DAKRKEKQEEEVD----------YESEEEEE---REGEENDD 1442
            A +     S         D KRKEK+                E E E E   R  EE D 
Sbjct: 84   AIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDK 143

Query: 1443 EDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRV 1502
               + ER   RE AR+   ++ +     E        + + +K    Q+ +   A ERR 
Sbjct: 144  ARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRK 203

Query: 1503 --QAVREI----HPFIDDYQYDTEESLWCQVTVKLP 1532
              +A RE+        +DY    + S W +   + P
Sbjct: 204  EREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 239


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
            member B [Homo sapiens]
          Length = 251

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 4/85 (4%)

Query: 1384 GRSRGEQEG---DEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEEN 1440
            G  R +QE    D E +G   + E EEG+ D  D   ++ +EEE D E +E+E+ EG+E+
Sbjct: 147  GYDREDQEAPDSDAEVDGVDEEEEDEEGE-DEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205

Query: 1441 DDEDMQEERNPHREGARKTQEQDEE 1465
            DDE  +EE     +   + +++DEE
Sbjct: 206  DDEVSEEEEEFGLDEEDEDEDEDEE 230



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 26/77 (33%), Positives = 44/77 (57%)

Query: 1389 EQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEE 1448
            ++EG++EE+    D E EE D +  + +  E  E++ +   EEEE    EE++DED  EE
Sbjct: 171  DEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEE 230

Query: 1449 RNPHREGARKTQEQDEE 1465
                 +G ++ +E D+E
Sbjct: 231  EEEGGKGEKRKRETDDE 247



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 26/72 (36%), Positives = 41/72 (56%)

Query: 1402 DAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQE 1461
            D EA + DA+      +E+ EE  D E E++E+ E EE D+ED ++E     E   +  E
Sbjct: 152  DQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSE 211

Query: 1462 QDEEVGLGTEED 1473
            ++EE GL  E++
Sbjct: 212  EEEEFGLDEEDE 223



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)

Query: 1374 QRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAE-EGDADASDAKRKEKQEEEVDYESEEE 1432
            + + D  GE      +++G+EEE     D + + EGD D  D   +E++E  +D E E+E
Sbjct: 167  EEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED-DDEVSEEEEEFGLDEEDEDE 225

Query: 1433 EEREGEENDDEDMQEERNPHREG 1455
            +E E EE   +  + +R    EG
Sbjct: 226  DEDEEEEEGGKGEKRKRETDDEG 248



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 12/67 (17%)

Query: 1388 GEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREG---------- 1437
            GE+E  +EE+    D E +E D + S+ + +   +EE + E E+EEE EG          
Sbjct: 185  GEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRET 244

Query: 1438 --EENDD 1442
              E  DD
Sbjct: 245  DDEGEDD 251



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 17/63 (26%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 1411 DASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGT 1470
            D  D + +E  + + + +  +EEE + E  D+ED +++ +   E   +  ++DE+V  G 
Sbjct: 146  DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEED-EDDEDGEEEEFDEEDDEDEDVE-GD 203

Query: 1471 EED 1473
            E+D
Sbjct: 204  EDD 206


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 41/135 (30%), Positives = 60/135 (44%), Gaps = 19/135 (14%)

Query: 1343 ETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVD 1402
            ET    L  E  +++   A    N +     + DL    E      E+E +EEEE    +
Sbjct: 1313 ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEE--EEEEEEEEEEEEEEE--E 1368

Query: 1403 AEAEEG----DADASDAKRKEKQEEEV-----------DYESEEEEEREGEENDDEDMQE 1447
             E EEG    + D   AK +EK+E E+           D+E EEEE+ E   N+D D  +
Sbjct: 1369 GEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADD 1428

Query: 1448 ERNPHREGARKTQEQ 1462
            E + H E A   +E+
Sbjct: 1429 EDDSHMESAEVEKEE 1443



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 18/51 (35%), Positives = 32/51 (62%)

Query: 1396 EEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQ 1446
            E G +++   E  + +  +   +E++EEE + E EEEEE E EE ++E++Q
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQ 1107



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 1389 EQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEE 1448
            ++E   EE    V      G+    D  + E++EEE   E EEEEE E EE ++E+    
Sbjct: 1321 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEE---EEEEEEEEEEEEGEEEEGGGN 1377

Query: 1449 RNPHREGARKTQEQDEEVGLGTEEDPSL 1476
                 +GA+  ++++ E+    E+   L
Sbjct: 1378 VEKDPDGAKSQEKEEPEISTEKEDSARL 1405



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 11/116 (9%)

Query: 1382 ELGRSRGEQEGDEEEEG------HIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEER 1435
            E G +   QE +  EE       +    E  E D    + + +E++EEE + E EE EE 
Sbjct: 1313 ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE 1372

Query: 1436 EGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQE 1491
            EG  N ++D    ++  +E    + E+++   L   E+        +  +P+H+++
Sbjct: 1373 EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEE-----EEDEEPSHNED 1423



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 6/61 (9%)

Query: 1424 EVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQP 1483
            E+  ES EEEE E +E ++E+ +EE     E   + +E++E      E   S P  LT+P
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE------ENIQSSPPRLTKP 1116

Query: 1484 R 1484
            +
Sbjct: 1117 Q 1117



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 16/57 (28%), Positives = 34/57 (59%)

Query: 1412 ASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGL 1468
            + ++  +E++EE+ + E EEEEE E EE ++E+ +EE   + + +     + + V +
Sbjct: 1065 SKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAI 1121



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 26/135 (19%)

Query: 1387 RGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQ 1446
            R E+E  E  E  +   E    +  A  +      E+  D   + EEE E EE ++E+ +
Sbjct: 1306 RIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEE 1365

Query: 1447 EERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVR 1506
            EE           + ++EE G   E+DP              SQE + PE    +  + R
Sbjct: 1366 EE-----------EGEEEEGGGNVEKDPD----------GAKSQEKEEPEISTEKEDSAR 1404

Query: 1507 EIHPFIDDYQYDTEE 1521
                 +DD++ + EE
Sbjct: 1405 -----LDDHEEEEEE 1414


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 1/89 (1%)

Query: 1378 DNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREG 1437
            ++  E     GE+  ++ +E    D E EEGD +  +   +E ++++ D E  E+EE E 
Sbjct: 97   EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156

Query: 1438 EENDDEDMQEERNPHREGARKTQ-EQDEE 1465
            EE ++E+ +EE   H+     T+  QD E
Sbjct: 157  EEEEEEEEEEENEDHQMNCHNTRIMQDTE 185



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 6/94 (6%)

Query: 1372 ATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEE 1431
            A + D  +  E   S G ++ DE+EE      E EE   D  +   +++++EE D E EE
Sbjct: 79   AVKADSSSVDECDDSDGTEDMDEKEED-----EGEEYSEDNDEPGDEDEEDEEGDREEEE 133

Query: 1432 EEEREGEENDDEDMQEERNPHREGARKTQEQDEE 1465
            E E E +E+DDED ++  +   E   + +E++EE
Sbjct: 134  EIEEE-DEDDDEDGEDVEDEEEEEEEEEEEEEEE 166



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 32/89 (35%), Positives = 45/89 (50%), Gaps = 6/89 (6%)

Query: 1378 DNAGELGRSRGEQEGDEEEEGHIVDAEAEEG--DADASDAKRKEKQEEEVDYESEEEEER 1435
            ++ GE      ++ GDE+EE    D E EE   + D  D +  E  E+E + E EEEEE 
Sbjct: 104  EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEE 163

Query: 1436 EGEENDDEDMQEERNPHREGARKTQEQDE 1464
            E EEN+D  M    N H     +  E+D+
Sbjct: 164  EEEENEDHQM----NCHNTRIMQDTEKDD 188



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 2/91 (2%)

Query: 1383 LGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDD 1442
            L + R  Q+   +E        A + D+ + D        E++D + E+E E   E+ND+
Sbjct: 57   LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116

Query: 1443 EDMQEERNPHREGARKTQEQDEEVGLGTEED 1473
               ++E +   EG R+ +E+ EE     +ED
Sbjct: 117  PGDEDEED--EEGDREEEEEIEEEDEDDDED 145


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
            sapiens]
          Length = 600

 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 36/165 (21%), Positives = 67/165 (40%), Gaps = 12/165 (7%)

Query: 1355 KKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASD 1414
            K ++ K    R     R  +R+     E  R R ++   ++E     + E E G    +D
Sbjct: 85   KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144

Query: 1415 AKRKEKQEEEVDYESEEEEEREGEENDDEDMQE------------ERNPHREGARKTQEQ 1462
             +R+ +++ + + E E + +RE +   + + Q+            ER   RE   KT+++
Sbjct: 145  GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204

Query: 1463 DEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVRE 1507
              E G   E +        + R+    ++ Q     ER  QA RE
Sbjct: 205  HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 4/111 (3%)

Query: 1355 KKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASD 1414
            +K+  +    R    +R  QR+ +   E  R R  +   E E     + E +       +
Sbjct: 285  RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDR----EKE 340

Query: 1415 AKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEE 1465
             +RK K++ E+D E   +  REG    + + + ER   R+ AR+ +E++ +
Sbjct: 341  RERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 43/162 (26%), Positives = 67/162 (41%), Gaps = 14/162 (8%)

Query: 1352 ESIKKKNNKASAFRNVNTRRATQRDLDNAGELGR-SRGEQEGDEEEEGHIVDAEAEEGDA 1410
            E+  +   K    R  + +R T+R+ +   E  R S  E E D+E E         E D 
Sbjct: 217  ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE--------RERDR 268

Query: 1411 DASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQ-----EQDEE 1465
            D    +R++++E + D + +   ER+ E     + Q ER   RE  RK +     E++ E
Sbjct: 269  DRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERE 328

Query: 1466 VGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVRE 1507
                TE D        + R+    +E       E R QA RE
Sbjct: 329  RQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERE 370



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 35/115 (30%), Positives = 54/115 (46%), Gaps = 10/115 (8%)

Query: 1352 ESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDAD 1411
            E  +K+  +    RN  T R  +R  +   E  R R  Q   E EE         E D D
Sbjct: 342  ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE--------RERDRD 393

Query: 1412 ASDAKRKEKQ-EEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEE 1465
                K +E+Q E++ D + E E++RE E++ + +   ER   RE  +K +E+D E
Sbjct: 394  RDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE-KQKGRERDRE 447



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 40/156 (25%), Positives = 61/156 (39%), Gaps = 23/156 (14%)

Query: 1355 KKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASD 1414
            +++  K    R  + +R  +R+ D   +  R R  Q   E+E     D E +        
Sbjct: 63   ERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD-------- 114

Query: 1415 AKRKEKQEEEVDYESEEEEEREGEENDDE--DMQEERNPHREGARKTQEQ-DEEVGLGTE 1471
              R+ ++E     E E E EREGE   D   D Q ER   R+  ++ + Q D E    TE
Sbjct: 115  --RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172

Query: 1472 EDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVRE 1507
             +          R+    +E    E  ER  Q  +E
Sbjct: 173  RN----------RQKEREREKNRQERRERERQREKE 198



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 43/171 (25%), Positives = 66/171 (38%), Gaps = 19/171 (11%)

Query: 1352 ESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAE----- 1406
            E  ++K  +    R     R  QR+ +N  E    R  + G E E     + E E     
Sbjct: 172  ERNRQKEREREKNRQERRERERQREKENKTE---DRHSERGRERERERETETETERKRQT 228

Query: 1407 --EGDADASDAKRKEKQEEEV---DYESEEEEEREGEENDDED-----MQEERNPHREGA 1456
              E D      + +EKQ E     + E+E ++ERE E + D D      + ER   R+  
Sbjct: 229  DRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288

Query: 1457 RKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVRE 1507
            R+T E+D E     E          + RK    +E +     +R  +  RE
Sbjct: 289  RRT-ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE 338



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 11/118 (9%)

Query: 1352 ESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDAD 1411
            E  +++N K    R     R  QR+ +   E  R R  +   E +     +   + G   
Sbjct: 308  ERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDR----ERNRQTGREG 363

Query: 1412 ASDAKRKEKQEEEVDYESEEEEEREGEEND-DEDMQEER----NPHREGARKTQEQDE 1464
               A+R+ ++E E D +S  E  RE  E D D D Q+ER       R+G R+T++Q E
Sbjct: 364  RRQAERERERERERDRQSARE--REERERDRDRDRQKERERQTEKDRDGQRETEKQRE 419



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 13/108 (12%)

Query: 1370 RRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAE------EGDADASDAKRKEK--- 1420
            RR   ++      LG++  + +GD+ E     + E        E + D    +R+EK   
Sbjct: 29   RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88

Query: 1421 ----QEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDE 1464
                +  E   + E+E ER+ +   D   ++ERN  +E  R+T+ + E
Sbjct: 89   RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 39/173 (22%), Positives = 67/173 (38%), Gaps = 21/173 (12%)

Query: 1355 KKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEG------ 1408
            K++  +    R   T R  Q++ +      + R E+E   E+E    D  +E G      
Sbjct: 157  KERERQTDRERQRQTERNRQKEREREKNR-QERRERERQREKENKTEDRHSERGRERERE 215

Query: 1409 -----------DADAS-DAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGA 1456
                         D   D +RK ++E E   E E   ERE E + + + + +R+  R+  
Sbjct: 216  RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275

Query: 1457 RKTQEQ--DEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVRE 1507
            +K +E+  D +    TE D        + R+    +E       ER  +  RE
Sbjct: 276  QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERE 328



 Score = 39.7 bits (91), Expect = 0.026
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 6/100 (6%)

Query: 1365 RNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEE 1424
            R   T R  QR  +   E  R R  Q   E E       E E       + +R+ +++ E
Sbjct: 279  RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER------ERERERERQRE 332

Query: 1425 VDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDE 1464
             + + E+E ER+ +   + D +  R   REG R+ + + E
Sbjct: 333  TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372



 Score = 35.0 bits (79), Expect = 0.63
 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 6/103 (5%)

Query: 1409 DADASDAKRKEKQEE----EVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDE 1464
            DAD  D +R  +Q+E        ++E E +R+ E   ++D   +R+ HRE  ++ +E++ 
Sbjct: 48   DADGDDRERN-RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRE-RQRDREKER 105

Query: 1465 EVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVRE 1507
            E     E D        + ++     E +G    +R+    RE
Sbjct: 106  ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148



 Score = 31.6 bits (70), Expect = 7.0
 Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 13/114 (11%)

Query: 1365 RNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEE 1424
            R  + +R  + + D   E  R R  +   E E     + E E       + +R+ ++E E
Sbjct: 281  RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER------ERERERQRETE 334

Query: 1425 VDYESEEEEER------EGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEE 1472
             D E E E +R      + E N     +  R   RE  R+ +E+D +     EE
Sbjct: 335  RDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE-RERDRQSAREREE 387


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 44/182 (24%), Positives = 74/182 (40%), Gaps = 18/182 (9%)

Query: 1352 ESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDAD 1411
            E  K+K  +    R+ +  R  +RD D   E  R R  +   +  +      E       
Sbjct: 334  EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR---- 389

Query: 1412 ASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDE------E 1465
              D +R+ ++E E + E E E ERE E   + + + ER   ++  R+  E+D       E
Sbjct: 390  --DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLE 447

Query: 1466 VGLGTEE---DPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVRE---IHPFIDDYQYDT 1519
              L  +E      L     + RK T   E +     ERR +  +E   +  F++DY  D 
Sbjct: 448  RKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDR 507

Query: 1520 EE 1521
            ++
Sbjct: 508  DD 509



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/141 (21%), Positives = 63/141 (44%), Gaps = 3/141 (2%)

Query: 1370 RRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYES 1429
            R    R++    +  +   E++G +E+E   ++ E  E + +    + + ++E E + E 
Sbjct: 274  RDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERER 333

Query: 1430 EEEEEREGEENDDEDMQEERNPHREGAR---KTQEQDEEVGLGTEEDPSLPALLTQPRKP 1486
            E E+E+E E   + D   +R   R+  R   + +++D E      +D S     ++ R+ 
Sbjct: 334  EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRER 393

Query: 1487 THSQEPQGPEAMERRVQAVRE 1507
               +E +     ER  +  RE
Sbjct: 394  ERERERERERERERERERERE 414



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 42/160 (26%), Positives = 79/160 (49%), Gaps = 13/160 (8%)

Query: 1309 QNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFM--ETRFFKLLMESIKKKNNKASAFR- 1365
            Q + + +++R +     Y ++ +  R E+  R M  E +  K  +E      +    +R 
Sbjct: 458  QERLKNWEIRERKKTREYEKEAE--REEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRG 515

Query: 1366 NVNTRRATQRDLD-NAGELGRSRGEQEGDEEE-----EGHI-VDAEAEEGDADASDAKRK 1418
            +   +R   R+ +  A E  R R ++E +E       EGH   DAE +  + +A + +R+
Sbjct: 516  SALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEA-ERRRQ 574

Query: 1419 EKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARK 1458
             + ++E + E EEEE++E EE  +E M+EE  P ++   K
Sbjct: 575  PQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLK 614



 Score = 38.5 bits (88), Expect = 0.057
 Identities = 50/249 (20%), Positives = 92/249 (36%), Gaps = 22/249 (8%)

Query: 1271 TKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEKQNKFQVYQLRFQFLPHAYY--- 1327
            TK+  + +K   + L R    E+       +S   ++K+ K +    RF   P   Y   
Sbjct: 200  TKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLI 259

Query: 1328 -----------QQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRD 1376
                       + ++ L   +I +F +T   K L E   KK  +         RR  +R+
Sbjct: 260  TKEDINAIEMEEDKRDLISREISKFRDTH--KKLEEEKGKKEKERQEIEK--ERRERERE 315

Query: 1377 LDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEK---QEEEVDYESEEEE 1433
             +   E      E+E + E E         E D D    K +++   +E + D + E   
Sbjct: 316  RERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSS 375

Query: 1434 EREGEENDDEDMQEERNPHREGAR-KTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEP 1492
            +R  + +   +   +R   RE  R + +E++ E     E +        + +     +E 
Sbjct: 376  DRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREE 435

Query: 1493 QGPEAMERR 1501
               +A ERR
Sbjct: 436  DEEDAYERR 444



 Score = 31.6 bits (70), Expect = 7.0
 Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 1/88 (1%)

Query: 1378 DNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREG 1437
            D   E+     +++ ++EE   I      EG  D     ++ +QE E   + + ++E E 
Sbjct: 524  DREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPES 583

Query: 1438 EENDDEDMQEERNPHREGARKTQEQDEE 1465
            EE ++E+ QE+     E   + +E +++
Sbjct: 584  EE-EEEEKQEKEEKREEPMEEEEEPEQK 610



 Score = 31.6 bits (70), Expect = 7.0
 Identities = 25/101 (24%), Positives = 41/101 (40%), Gaps = 22/101 (21%)

Query: 1406 EEGDADASDAKRKEKQEEEVDY-----------------ESEEEEEREGEENDDEDMQEE 1448
            +E +AD  D KR++++ EE+                   E E E  R+ +   + + +EE
Sbjct: 527  KEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEE 586

Query: 1449 RNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHS 1489
                +E   K +E  EE     EE+P     L    +P  S
Sbjct: 587  EEEKQEKEEKREEPMEE-----EEEPEQKPCLKPTLRPISS 622


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
            member A [Homo sapiens]
          Length = 249

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 29/78 (37%), Positives = 46/78 (58%), Gaps = 4/78 (5%)

Query: 1389 EQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEE--REGEENDDEDMQ 1446
            ++E DE+EE +  DA+  E + D  +   +E +EE+V  E EE+EE   +GE +D+ED +
Sbjct: 169  DEEEDEDEEEYDEDAQVVEDEEDEDE--EEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEE 226

Query: 1447 EERNPHREGARKTQEQDE 1464
            E     R   RK + +DE
Sbjct: 227  ELGEEERGQKRKREPEDE 244



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 9/92 (9%)

Query: 1384 GRSRGEQEG-DEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDD 1442
            G  R ++E  D + EG++   + EE D D      +E+ +E+     +EE+E E EE ++
Sbjct: 147  GYDRDDKEAPDSDAEGYVEGLDDEEEDED------EEEYDEDAQVVEDEEDEDEEEEGEE 200

Query: 1443 EDMQEERNPHREGAR--KTQEQDEEVGLGTEE 1472
            ED+  E     EG    +  ++++E  LG EE
Sbjct: 201  EDVSGEEEEDEEGYNDGEVDDEEDEEELGEEE 232



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 17/70 (24%), Positives = 35/70 (50%)

Query: 1404 EAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQD 1463
            + E  D+DA         EEE + E E +E+ +  E+++++ +EE     + + + +E +
Sbjct: 152  DKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDE 211

Query: 1464 EEVGLGTEED 1473
            E    G  +D
Sbjct: 212  EGYNDGEVDD 221


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 4/83 (4%)

Query: 1386 SRGEQEGDEE--EEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDE 1443
            +  E+EG EE  EE   V+ +AEE +    D + +E++EEE   E EEEEE E  E D+ 
Sbjct: 198  TENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE--EEEEEEEEEEYEQDER 255

Query: 1444 DMQEERNPHREGARKTQEQDEEV 1466
            D +EE N +   +  +    E V
Sbjct: 256  DQKEEGNDYDTRSEASDSGSESV 278



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 42/159 (26%), Positives = 68/159 (42%), Gaps = 12/159 (7%)

Query: 1327 YQQEKCLRPEDILRFMETRFFKLLM----ESIKKKNNKASAFRNVNTRRATQRDLDNAGE 1382
            Y+ E+  R E   R    R  +L      E  K +  K    +    RRA     D +  
Sbjct: 95   YKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSER 154

Query: 1383 LG------RSRGEQEGDEEEEGHIVDAEAEEGDADASDAK--RKEKQEEEVDYESEEEEE 1434
            +G       SR  Q   EE       ++ E G + +SD +    E +EE V+ + EE+EE
Sbjct: 155  IGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEE 214

Query: 1435 REGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEED 1473
             E +  +DE++ E+     E   + +E++EE     E+D
Sbjct: 215  VEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD 253



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 27/72 (37%), Positives = 41/72 (56%), Gaps = 2/72 (2%)

Query: 1386 SRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDED- 1444
            S  EQ  + E E   V+ + EE +    DA+  E+ +E+ + E EEEEE E EE ++E+ 
Sbjct: 190  SSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249

Query: 1445 -MQEERNPHREG 1455
              Q+ER+   EG
Sbjct: 250  YEQDERDQKEEG 261



 Score = 38.1 bits (87), Expect = 0.074
 Identities = 25/114 (21%), Positives = 44/114 (38%)

Query: 1409 DADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGL 1468
            + D   ++  +  +EEV+ E    +   G     ++         EG  +  E+DEEV  
Sbjct: 158  EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217

Query: 1469 GTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREIHPFIDDYQYDTEES 1522
              EED  +     +  +    +E +  E  E   Q  R+     +DY   +E S
Sbjct: 218  DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEAS 271


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 4/83 (4%)

Query: 1386 SRGEQEGDEE--EEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDE 1443
            +  E+EG EE  EE   V+ +AEE +    D + +E++EEE   E EEEEE E  E D+ 
Sbjct: 198  TENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE--EEEEEEEEEEYEQDER 255

Query: 1444 DMQEERNPHREGARKTQEQDEEV 1466
            D +EE N +   +  +    E V
Sbjct: 256  DQKEEGNDYDTRSEASDSGSESV 278



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 42/159 (26%), Positives = 68/159 (42%), Gaps = 12/159 (7%)

Query: 1327 YQQEKCLRPEDILRFMETRFFKLLM----ESIKKKNNKASAFRNVNTRRATQRDLDNAGE 1382
            Y+ E+  R E   R    R  +L      E  K +  K    +    RRA     D +  
Sbjct: 95   YKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSER 154

Query: 1383 LG------RSRGEQEGDEEEEGHIVDAEAEEGDADASDAK--RKEKQEEEVDYESEEEEE 1434
            +G       SR  Q   EE       ++ E G + +SD +    E +EE V+ + EE+EE
Sbjct: 155  IGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEE 214

Query: 1435 REGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEED 1473
             E +  +DE++ E+     E   + +E++EE     E+D
Sbjct: 215  VEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD 253



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 27/72 (37%), Positives = 41/72 (56%), Gaps = 2/72 (2%)

Query: 1386 SRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDED- 1444
            S  EQ  + E E   V+ + EE +    DA+  E+ +E+ + E EEEEE E EE ++E+ 
Sbjct: 190  SSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249

Query: 1445 -MQEERNPHREG 1455
              Q+ER+   EG
Sbjct: 250  YEQDERDQKEEG 261



 Score = 38.1 bits (87), Expect = 0.074
 Identities = 25/114 (21%), Positives = 44/114 (38%)

Query: 1409 DADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGL 1468
            + D   ++  +  +EEV+ E    +   G     ++         EG  +  E+DEEV  
Sbjct: 158  EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217

Query: 1469 GTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREIHPFIDDYQYDTEES 1522
              EED  +     +  +    +E +  E  E   Q  R+     +DY   +E S
Sbjct: 218  DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEAS 271


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 5/91 (5%)

Query: 1388 GEQEGDEEEEGHIV---DAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDED 1444
            GE  G EE E  +    + E+E G+   S+ + + ++E E + ESE+E + E EE+ +E+
Sbjct: 73   GEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEE 132

Query: 1445 MQEERNPHREGARKTQEQDEEVGLGTEEDPS 1475
            M++E+    E     QE+ E    G  E  S
Sbjct: 133  MEDEQ--ESEAEEDNQEEGESEAEGETEAES 161



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 25/85 (29%), Positives = 41/85 (48%)

Query: 1382 ELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEEND 1441
            E+    GE+   EEE     ++E EE   D SD + +E  EEE++ E E E E + +E  
Sbjct: 90   EIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEG 149

Query: 1442 DEDMQEERNPHREGARKTQEQDEEV 1466
            + + + E     E   + + + E V
Sbjct: 150  ESEAEGETEAESEFDPEIEMEAERV 174



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 33/116 (28%), Positives = 58/116 (50%), Gaps = 12/116 (10%)

Query: 1374 QRDLDN-AGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEE 1432
            +R++++ AGE   S  E E +EE E    + E+E+   + S+   +E+ E+E + E+EE+
Sbjct: 88   EREIESEAGEESESEEESESEEESE---TEEESEDESDEESEEDSEEEMEDEQESEAEED 144

Query: 1433 EEREGE---ENDDE-----DMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALL 1480
             + EGE   E + E     D + E    R   RK  +   ++    +ED  L  +L
Sbjct: 145  NQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVL 200



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 1384 GRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDE 1443
            G+   E + ++E E      E  E + ++   +  E +EE  D   EE EE   EE +DE
Sbjct: 77   GKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDE 136

Query: 1444 DMQEERNPHREGARKTQEQDEEVGLGTEEDPSL 1476
               E    ++E      E + E    +E DP +
Sbjct: 137  QESEAEEDNQEEGESEAEGETEA--ESEFDPEI 167



 Score = 35.4 bits (80), Expect = 0.48
 Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 19/113 (16%)

Query: 1405 AEEGDADASDAKRKEKQEEEVDYE----SEEEEEREGEENDDEDMQEERNPHREGARKTQ 1460
            A+   A   +A+ K +QE E++ E    SE EEE E EE  + + + E            
Sbjct: 71   ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESE-----------D 119

Query: 1461 EQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREIHPFID 1513
            E DEE    +EED        Q  +     + +G    E   +A  E  P I+
Sbjct: 120  ESDEE----SEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIE 168


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 9/95 (9%)

Query: 1402 DAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQE 1461
            DA +EE          +E+ EEE + E EEEE+ E EE ++E+ +EE     E   + +E
Sbjct: 242  DAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEE---EEEE 298

Query: 1462 QDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPE 1496
            ++EE     EE+ + P ++ Q    +H+   + PE
Sbjct: 299  EEEE-----EEEEAAPDVIFQ-EDTSHTSAQKAPE 327



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 26/84 (30%), Positives = 44/84 (52%)

Query: 1406 EEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEE 1465
            EE D +  + + +E+++EE + E EEEEE E EE ++E+ +EE     E A     Q++ 
Sbjct: 258  EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDT 317

Query: 1466 VGLGTEEDPSLPALLTQPRKPTHS 1489
                 ++ P L    +   KP +S
Sbjct: 318  SHTSAQKAPELRGPESPSPKPEYS 341



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 13/137 (9%)

Query: 1372 ATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEE 1431
            A++      G L     ++E +EEEE    D E EE + +  + + +E++EEE + E EE
Sbjct: 244  ASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303

Query: 1432 EEEREGE---ENDDEDMQEERNPHREGARKTQEQDE-----EVGLGTEEDPSLPALLTQP 1483
            EEE   +   + D      ++ P   G      + E     EV    ++D       T  
Sbjct: 304  EEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDED-----THS 358

Query: 1484 RKPTHSQEPQGPEAMER 1500
            RK T + E +  + M R
Sbjct: 359  RKSTVTDESEMQDMMTR 375


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,067,432
Number of Sequences: 37866
Number of extensions: 3204469
Number of successful extensions: 33400
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 450
Number of HSP's successfully gapped in prelim test: 545
Number of HSP's that attempted gapping in prelim test: 14788
Number of HSP's gapped (non-prelim): 8028
length of query: 1720
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1604
effective length of database: 13,855,062
effective search space: 22223519448
effective search space used: 22223519448
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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