Guide to the Human Genome
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Name: AICDA Sequence: fasta or formatted (198aa) NCBI GI: 10190700
Description:

activation-induced cytidine deaminase

Referenced in:

B cells
RNA Editing and Other RNA Modifications

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.1         10           1
 C cysteine            3.5          7           1
 D aspartate           6.6         13           2
 E glutamate           5.1         10           1
 F phenylalanine       7.1         14           1
 G glycine             4.5          9           1
 H histidine           2.5          5           1
 I isoleucine          2.5          5           1
 K lysine              4.0          8           1
 L leucine            12.6         25           2
 M methionine          1.5          3           1
 N asparagine          4.5          9           1
 P proline             2.5          5           1
 Q glutamine           1.5          3           1
 R arginine           13.1         26           2
 S serine              5.1         10           1
 T threonine           4.5          9           1
 V valine              5.1         10           2
 W tryptophan          3.0          6           1
 Y tyrosine            5.6         11           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   activation-induced cytidine deaminase 
APOBEC3G              0.317   apolipoprotein B mRNA editing enzyme, catalytic poly...
APOBEC3C              0.300   apolipoprotein B mRNA editing enzyme, catalytic poly...
APOBEC3F              0.300   apolipoprotein B mRNA editing enzyme, catalytic poly...
APOBEC3B              0.287   apolipoprotein B mRNA editing enzyme, catalytic poly...
APOBEC3A              0.285   phorbolin 1 
APOBEC3D              0.270   apolipoprotein B mRNA editing enzyme, catalytic pol...
APOBEC3H              0.212   apolipoprotein B mRNA editing enzyme, catalytic poly...
APOBEC2               0.204   apolipoprotein B mRNA editing enzyme, catalytic polyp...
APOBEC1               0.154   apolipoprotein B mRNA editing enzyme 
ARHGAP18              0.010   Rho GTPase activating protein 18 
TMEM66                0.008   transmembrane protein 66 
PAPOLB                0.008   poly(A) polymerase beta (testis specific) 
EIF3CL                0.008   eukaryotic translation initiation factor 3, subunit...
MFI2                  0.008   melanoma-associated antigen p97 isoform 1 precursor...
EIF3C                 0.008   eukaryotic translation initiation factor 3, subunit ...
EIF3C                 0.008   eukaryotic translation initiation factor 3, subunit C...
RND3                  0.005   ras homolog gene family, member E 
TMEM2                 0.005   transmembrane protein 2 isoform b 
TMEM2                 0.005   transmembrane protein 2 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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