Search of human proteins with 186910296

Search of human proteins with 186910296

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|186910296 haptoglobin isoform 2 preproprotein [Homo sapiens]
         (347 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|186910296 haptoglobin isoform 2 preproprotein [Homo sapiens]       722   0.0  
gi|4826762 haptoglobin isoform 1 preproprotein [Homo sapiens]         669   0.0  
gi|45580723 haptoglobin-related protein [Homo sapiens]                653   0.0  
gi|66347875 complement component 1, r subcomponent [Homo sapiens]     178   6e-45
gi|4502495 complement component 1, s subcomponent precursor [Hom...   164   1e-40
gi|41393602 complement component 1, s subcomponent precursor [Ho...   164   1e-40
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr...   150   1e-36
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr...   150   2e-36
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr...   141   8e-34
gi|7706083 complement component 1, r subcomponent-like precursor...   136   3e-32
gi|10518503 coagulation factor VII isoform b precursor [Homo sap...   122   4e-28
gi|4503645 coagulation factor VII isoform a precursor [Homo sapi...   122   4e-28
gi|148806900 epidermis-specific serine protease-like protein [Ho...   119   3e-27
gi|4503625 coagulation factor X preproprotein [Homo sapiens]          112   4e-25
gi|4503649 coagulation factor IX preproprotein [Homo sapiens]         106   3e-23
gi|13994276 marapsin [Homo sapiens]                                   105   8e-23
gi|4506115 protein C [Homo sapiens]                                   104   1e-22
gi|4506153 prostasin preproprotein [Homo sapiens]                     102   7e-22
gi|110578663 hypothetical protein LOC203074 [Homo sapiens]            101   1e-21
gi|4503635 coagulation factor II preproprotein [Homo sapiens]         100   3e-21
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]            99   6e-21
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]            98   1e-20
gi|4503627 coagulation factor XI precursor [Homo sapiens]              97   3e-20
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]           97   3e-20
gi|117956391 protease, serine, 33 [Homo sapiens]                       96   4e-20
gi|223942069 enterokinase precursor [Homo sapiens]                     96   6e-20
gi|40254871 transmembrane protease, serine 11E [Homo sapiens]          96   6e-20
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]           96   6e-20
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]        96   6e-20
gi|4505881 plasminogen [Homo sapiens]                                  95   1e-19

>gi|186910296 haptoglobin isoform 2 preproprotein [Homo sapiens]
          Length = 347

 Score =  722 bits (1864), Expect = 0.0
 Identities = 347/347 (100%), Positives = 347/347 (100%)

Query: 1   MSALGAVIALLLWGQLFAVDSGNDVTDIADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRT 60
           MSALGAVIALLLWGQLFAVDSGNDVTDIADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRT
Sbjct: 1   MSALGAVIALLLWGQLFAVDSGNDVTDIADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRT 60

Query: 61  EGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKM 120
           EGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKM
Sbjct: 61  EGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKM 120

Query: 121 VSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLH 180
           VSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLH
Sbjct: 121 VSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLH 180

Query: 181 PNYSQVDIGLIKLKQKVSVNERVMPICLPSKDYAEVGRVGYVSGWGRNANFKFTDHLKYV 240
           PNYSQVDIGLIKLKQKVSVNERVMPICLPSKDYAEVGRVGYVSGWGRNANFKFTDHLKYV
Sbjct: 181 PNYSQVDIGLIKLKQKVSVNERVMPICLPSKDYAEVGRVGYVSGWGRNANFKFTDHLKYV 240

Query: 241 MLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAF 300
           MLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAF
Sbjct: 241 MLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAF 300

Query: 301 AVHDLEEDTWYATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN 347
           AVHDLEEDTWYATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN
Sbjct: 301 AVHDLEEDTWYATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN 347


>gi|4826762 haptoglobin isoform 1 preproprotein [Homo sapiens]
          Length = 406

 Score =  669 bits (1726), Expect = 0.0
 Identities = 319/319 (100%), Positives = 319/319 (100%)

Query: 29  ADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEA 88
           ADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEA
Sbjct: 88  ADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEA 147

Query: 89  VCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLN 148
           VCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLN
Sbjct: 148 VCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLN 207

Query: 149 HSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQVDIGLIKLKQKVSVNERVMPICL 208
           HSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQVDIGLIKLKQKVSVNERVMPICL
Sbjct: 208 HSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQVDIGLIKLKQKVSVNERVMPICL 267

Query: 209 PSKDYAEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSP 268
           PSKDYAEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSP
Sbjct: 268 PSKDYAEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSP 327

Query: 269 VGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYG 328
           VGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYG
Sbjct: 328 VGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYG 387

Query: 329 VYVKVTSIQDWVQKTIAEN 347
           VYVKVTSIQDWVQKTIAEN
Sbjct: 388 VYVKVTSIQDWVQKTIAEN 406


>gi|45580723 haptoglobin-related protein [Homo sapiens]
          Length = 348

 Score =  653 bits (1684), Expect = 0.0
 Identities = 317/348 (91%), Positives = 328/348 (94%), Gaps = 1/348 (0%)

Query: 1   MSALGAVIALLLWG-QLFAVDSGNDVTDIADDGCPKPPEIAHGYVEHSVRYQCKNYYKLR 59
           MS LGAVI+LLLWG QLFA+ SGNDVTDI+DD  PKPPEIA+GYVEH  RYQCKNYY+LR
Sbjct: 1   MSDLGAVISLLLWGRQLFALYSGNDVTDISDDRFPKPPEIANGYVEHLFRYQCKNYYRLR 60

Query: 60  TEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAK 119
           TEGDGVYTLN++KQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAK
Sbjct: 61  TEGDGVYTLNDKKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAK 120

Query: 120 MVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVL 179
           MVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVL
Sbjct: 121 MVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVL 180

Query: 180 HPNYSQVDIGLIKLKQKVSVNERVMPICLPSKDYAEVGRVGYVSGWGRNANFKFTDHLKY 239
           HPNY QVDIGLIKLKQKV VNERVMPICLPSK+YAEVGRVGYVSGWG++ NFK TDHLKY
Sbjct: 181 HPNYHQVDIGLIKLKQKVLVNERVMPICLPSKNYAEVGRVGYVSGWGQSDNFKLTDHLKY 240

Query: 240 VMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSA 299
           VMLPVADQ  CI HYEGST P+ K PKSPVGVQPILNEHTFC GMSKYQEDTCYGDAGSA
Sbjct: 241 VMLPVADQYDCITHYEGSTCPKWKAPKSPVGVQPILNEHTFCVGMSKYQEDTCYGDAGSA 300

Query: 300 FAVHDLEEDTWYATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN 347
           FAVHDLEEDTWYA GILSFDKSCAVAEYGVYVKVTSIQ WVQKTIAEN
Sbjct: 301 FAVHDLEEDTWYAAGILSFDKSCAVAEYGVYVKVTSIQHWVQKTIAEN 348


>gi|66347875 complement component 1, r subcomponent [Homo sapiens]
          Length = 705

 Score =  178 bits (452), Expect = 6e-45
 Identities = 109/323 (33%), Positives = 163/323 (50%), Gaps = 45/323 (13%)

Query: 48  VRYQCKN-YYKLRTEG------DGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPV 100
           ++Y C   YYK++T         GVYT   +  W N+  G+K+P C  VCGKP NP    
Sbjct: 402 IQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQR 461

Query: 101 QRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLF-LNHSENATAKDIA 159
           QRI+GG     G+FPWQ     H     G  L+ ++W+LT A  L+   H   + A    
Sbjct: 462 QRIIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNA---- 515

Query: 160 PTLTLYVGKKQLVE--------IEKVVLHPNYSQ-------VDIGLIKLKQKVSVNERVM 204
            +L +++G   + E        I +V +HP+Y Q        DI L++L+  V++   ++
Sbjct: 516 -SLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLL 574

Query: 205 PICLPSKD-YAEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKK 263
           PICLP  D + ++G +GYVSG+G     K    L++V LPVA+   C     G    +  
Sbjct: 575 PICLPDNDTFYDLGLMGYVSGFGVMEE-KIAHDLRFVRLPVANPQACENWLRGKNRMD-- 631

Query: 264 TPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCA 323
                     + +++ FCAG    ++D C GD+G  FAV D   D W ATGI+S+   C+
Sbjct: 632 ----------VFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCS 681

Query: 324 VAEYGVYVKVTSIQDWVQKTIAE 346
              YG Y KV +  DW++K + E
Sbjct: 682 -RGYGFYTKVLNYVDWIKKEMEE 703


>gi|4502495 complement component 1, s subcomponent precursor [Homo
           sapiens]
          Length = 688

 Score =  164 bits (415), Expect = 1e-40
 Identities = 114/340 (33%), Positives = 159/340 (46%), Gaps = 41/340 (12%)

Query: 33  CPKPPEIAHGYVEHS--------VRYQCKN-YYKLRTEGDGVYTLNNEKQWINKAVGDKL 83
           C  P  I +G VE          +RY C+  YY +   G G Y       W+N+ +G +L
Sbjct: 359 CGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPEL 418

Query: 84  PECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAK 143
           P+C  VCG P+ P    QRI+GG      +FPWQ   V   N   G  LINE W+LT A 
Sbjct: 419 PKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQ---VFFDNPWAGGALINEYWVLTAA- 474

Query: 144 NLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV-----------DIGLIK 192
           ++   + E           T  + K +++  E V +HP +  +           DI L++
Sbjct: 475 HVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVR 534

Query: 193 LKQKVSVNERVMPICLP--SKDYAEV-GRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQ 249
           LK  V +   V PICLP  S DY  + G +G +SGWGR         LK   LPVA   +
Sbjct: 535 LKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRK 594

Query: 250 CIRHYEGSTVPEKKTPKSPVGVQP-ILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEED 308
           C          E K  K     +  +   +  CAG  K   D+C GD+G AFAV D  + 
Sbjct: 595 C---------KEVKVEKPTADAEAYVFTPNMICAGGEKGM-DSCKGDSGGAFAVQDPNDK 644

Query: 309 T-WYATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN 347
           T +YA G++S+   C    YG+Y +V +  DW+ KT+ EN
Sbjct: 645 TKFYAAGLVSWGPQCGT--YGLYTRVKNYVDWIMKTMQEN 682


>gi|41393602 complement component 1, s subcomponent precursor [Homo
           sapiens]
          Length = 688

 Score =  164 bits (415), Expect = 1e-40
 Identities = 114/340 (33%), Positives = 159/340 (46%), Gaps = 41/340 (12%)

Query: 33  CPKPPEIAHGYVEHS--------VRYQCKN-YYKLRTEGDGVYTLNNEKQWINKAVGDKL 83
           C  P  I +G VE          +RY C+  YY +   G G Y       W+N+ +G +L
Sbjct: 359 CGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPEL 418

Query: 84  PECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAK 143
           P+C  VCG P+ P    QRI+GG      +FPWQ   V   N   G  LINE W+LT A 
Sbjct: 419 PKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQ---VFFDNPWAGGALINEYWVLTAA- 474

Query: 144 NLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV-----------DIGLIK 192
           ++   + E           T  + K +++  E V +HP +  +           DI L++
Sbjct: 475 HVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVR 534

Query: 193 LKQKVSVNERVMPICLP--SKDYAEV-GRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQ 249
           LK  V +   V PICLP  S DY  + G +G +SGWGR         LK   LPVA   +
Sbjct: 535 LKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRK 594

Query: 250 CIRHYEGSTVPEKKTPKSPVGVQP-ILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEED 308
           C          E K  K     +  +   +  CAG  K   D+C GD+G AFAV D  + 
Sbjct: 595 C---------KEVKVEKPTADAEAYVFTPNMICAGGEKGM-DSCKGDSGGAFAVQDPNDK 644

Query: 309 T-WYATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN 347
           T +YA G++S+   C    YG+Y +V +  DW+ KT+ EN
Sbjct: 645 TKFYAAGLVSWGPQCGT--YGLYTRVKNYVDWIMKTMQEN 682


>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
           precursor [Homo sapiens]
          Length = 699

 Score =  150 bits (380), Expect = 1e-36
 Identities = 104/343 (30%), Positives = 158/343 (46%), Gaps = 49/343 (14%)

Query: 33  CPKPPEIAHGYVEHSVR-----------YQCKN-YYKLRTEGDGVYTLNNEKQWINKAVG 80
           C  P E+ HG +  S R           Y C+  YYK+     G+YT + +  W+NK +G
Sbjct: 367 CRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLG 426

Query: 81  DKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHN--LTTGATLINEQWL 138
             LP C  VCG PK     + RI  G    KG+ PW A M+SH N     G +L+   W+
Sbjct: 427 RSLPTCLPVCGLPKFSRKLMARIFNGRPAQKGTTPWIA-MLSHLNGQPFCGGSLLGSSWI 485

Query: 139 LTTAKNLFLN-HSENATAKD---IAPT-LTLYVGK---------KQLVEIEKVVLHPNYS 184
           +T A  L  +   E+ T +D   ++P+   + +GK         +Q + ++   LHP Y 
Sbjct: 486 VTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYD 545

Query: 185 ----QVDIGLIKLKQKVSVNERVMPICLPSKDYAEVGRVGYVSGWGRNANFKFTDHLKYV 240
               + D+ L++L +   +N  VMPICLP     E G +  VSGWG+    +F + L  +
Sbjct: 546 PNTFENDVALVELLESPVLNAFVMPICLPEGPQQE-GAMVIVSGWGKQFLQRFPETLMEI 604

Query: 241 MLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAF 300
            +P+ D   C + Y     P KK           +     CAG  +  +D C GD+G   
Sbjct: 605 EIPIVDHSTCQKAY----APLKKK----------VTRDMICAGEKEGGKDACAGDSGGPM 650

Query: 301 AVHDLEEDTWYATGILSFDKSCAVAE-YGVYVKVTSIQDWVQK 342
              + E   WY  G +S+   C   + YGVY  +   +DW+Q+
Sbjct: 651 VTLNRERGQWYLVGTVSWGDDCGKKDRYGVYSYIHHNKDWIQR 693


>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
           precursor [Homo sapiens]
          Length = 728

 Score =  150 bits (379), Expect = 2e-36
 Identities = 107/357 (29%), Positives = 161/357 (45%), Gaps = 61/357 (17%)

Query: 33  CPKPPEIAHGYVEHSVR-----------YQCKN-YYKLRTEGDGVYTLNNEKQWINKAVG 80
           C  P E+ HG +  S R           Y C+  YYK+     G+YT + +  W+NK +G
Sbjct: 367 CRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLG 426

Query: 81  DKLPECEAVCGKP-KNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTT-------GATL 132
             LP C   CG+P ++  + V+RI+GG     G FPWQA +V                 L
Sbjct: 427 RSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGAL 486

Query: 133 INEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVE--------IEKVVLHPNYS 184
           ++  W+LT A  L     +          +T+Y+G   + +          +VVLHP+++
Sbjct: 487 LSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFN 546

Query: 185 ----QVDIGLIKLKQKVSVNERVMPICLP--SKDYAEVGRVGYVSGWG-RNANFK----- 232
                 DI L++L++ V +   VMP+CLP    +      +G V+GWG  N N       
Sbjct: 547 IQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEII 606

Query: 233 ------FTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSK 286
                  +D L+YV LPV    +C   YE  +     T            E+ FCAG  +
Sbjct: 607 SSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVT------------ENMFCAGYYE 654

Query: 287 YQEDTCYGDAGSAFAVHDLEEDTWYATGILSF--DKSCAVAE-YGVYVKVTSIQDWV 340
             +DTC GD+G AF + D     W   G++S+   + C   + YGVY KV++  DWV
Sbjct: 655 GGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWV 711


>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
           precursor [Homo sapiens]
          Length = 686

 Score =  141 bits (356), Expect = 8e-34
 Identities = 97/336 (28%), Positives = 143/336 (42%), Gaps = 38/336 (11%)

Query: 33  CPKPPEIAHGYVEHS-----------VRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGD 81
           C  P ++  G VE+            ++Y C+  +      DG Y    +  W +     
Sbjct: 366 CGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFWTSSKGEK 425

Query: 82  KLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTT 141
            LP CE VCG          RI GG     G FPWQ  ++     T    L+ + W+LT 
Sbjct: 426 SLPVCEPVCGLSARTTGG--RIYGGQKAKPGDFPWQVLILG--GTTAAGALLYDNWVLTA 481

Query: 142 AKNLFLNHSENATAKDIAP-TLTLYVGKKQLVEIEKVVLHPNYSQV-----DIGLIKLKQ 195
           A  ++     +A+A DI   TL            E V +H  Y+       DI LIKL  
Sbjct: 482 AHAVY-EQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNN 540

Query: 196 KVSVNERVMPICLPSKD---YAEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIR 252
           KV +N  + PICLP K+   +     +G  SGWG         +L YV +P+ D  +C  
Sbjct: 541 KVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTA 600

Query: 253 HYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYA 312
            YE    P              +  +  CAG+    +D+C GD+G A    D E + W+ 
Sbjct: 601 AYEKPPYPRGS-----------VTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFV 649

Query: 313 TGILSF-DKSCAVA-EYGVYVKVTSIQDWVQKTIAE 346
            GI+S+   +C  A +YGVY KV +   W++  I++
Sbjct: 650 GGIVSWGSMNCGEAGQYGVYTKVINYIPWIENIISD 685


>gi|7706083 complement component 1, r subcomponent-like precursor
           [Homo sapiens]
          Length = 487

 Score =  136 bits (342), Expect = 3e-32
 Identities = 89/310 (28%), Positives = 142/310 (45%), Gaps = 36/310 (11%)

Query: 48  VRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGH 107
           V+  C+  Y  +    G  T      W ++  G+++ +C  VCG+P  P    Q  LG  
Sbjct: 191 VQNHCQEPY-YQAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQNQTTLGSS 249

Query: 108 LDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVG 167
               G+FPWQA    H     G  L+ ++W+LT A  ++   S +        ++ +++G
Sbjct: 250 RAKLGNFPWQAFTSIHGR--GGGALLGDRWILTAAHTVYPKDSVSLRKNQ---SVNVFLG 304

Query: 168 KKQLVE--------IEKVVLHPNYSQV-------DIGLIKLKQKVSVNERVMPICLPSKD 212
              + E        + +VV+HP+Y Q        DI L++L+  + +   V+P+CLP  +
Sbjct: 305 HTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPDNE 364

Query: 213 YA-EVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGV 271
                G +GYVSG+G    +  T  LKY  LPVA ++ C    +    PE          
Sbjct: 365 TLYRSGLLGYVSGFGMEMGW-LTTELKYSRLPVAPREACNAWLQKRQRPE---------- 413

Query: 272 QPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYV 331
             + +++ FC G    +   C GD+GS + V D     W ATGI+S+   C    Y  Y 
Sbjct: 414 --VFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEG-YDFYT 470

Query: 332 KVTSIQDWVQ 341
           KV S  DW++
Sbjct: 471 KVLSYVDWIK 480


>gi|10518503 coagulation factor VII isoform b precursor [Homo
           sapiens]
          Length = 444

 Score =  122 bits (307), Expect = 4e-28
 Identities = 85/275 (30%), Positives = 133/275 (48%), Gaps = 30/275 (10%)

Query: 84  PECEAVCGK-----PKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWL 138
           P  E  CGK      +N + P  RI+GG +  KG  PWQ  ++ +     G TLIN  W+
Sbjct: 167 PTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWV 226

Query: 139 LTTAKNL-FLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNY----SQVDIGLIKL 193
           ++ A     + +  N  A      L+ + G +Q   + +V++   Y    +  DI L++L
Sbjct: 227 VSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRL 286

Query: 194 KQKVSVNERVMPICLPSKDYAE----VGRVGYVSGWGRNANFKFTD-HLKYVMLPVADQD 248
            Q V + + V+P+CLP + ++E      R   VSGWG+  +   T   L  + +P     
Sbjct: 287 HQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQ 346

Query: 249 QCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEED 308
            C++                VG  P + E+ FCAG S   +D+C GD+G   A H     
Sbjct: 347 DCLQQ------------SRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATH--YRG 392

Query: 309 TWYATGILSFDKSCA-VAEYGVYVKVTSIQDWVQK 342
           TWY TGI+S+ + CA V  +GVY +V+   +W+QK
Sbjct: 393 TWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQK 427


>gi|4503645 coagulation factor VII isoform a precursor [Homo
           sapiens]
          Length = 466

 Score =  122 bits (307), Expect = 4e-28
 Identities = 85/275 (30%), Positives = 133/275 (48%), Gaps = 30/275 (10%)

Query: 84  PECEAVCGK-----PKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWL 138
           P  E  CGK      +N + P  RI+GG +  KG  PWQ  ++ +     G TLIN  W+
Sbjct: 189 PTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWV 248

Query: 139 LTTAKNL-FLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNY----SQVDIGLIKL 193
           ++ A     + +  N  A      L+ + G +Q   + +V++   Y    +  DI L++L
Sbjct: 249 VSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRL 308

Query: 194 KQKVSVNERVMPICLPSKDYAE----VGRVGYVSGWGRNANFKFTD-HLKYVMLPVADQD 248
            Q V + + V+P+CLP + ++E      R   VSGWG+  +   T   L  + +P     
Sbjct: 309 HQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQ 368

Query: 249 QCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEED 308
            C++                VG  P + E+ FCAG S   +D+C GD+G   A H     
Sbjct: 369 DCLQQ------------SRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATH--YRG 414

Query: 309 TWYATGILSFDKSCA-VAEYGVYVKVTSIQDWVQK 342
           TWY TGI+S+ + CA V  +GVY +V+   +W+QK
Sbjct: 415 TWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQK 449


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  119 bits (299), Expect = 3e-27
 Identities = 77/275 (28%), Positives = 136/275 (49%), Gaps = 41/275 (14%)

Query: 88  AVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFL 147
           +VCG+P   +    R++GG   A G +PWQ  +   HN   G +L++E+ +LT A     
Sbjct: 17  SVCGQPVYSS----RVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAA----- 67

Query: 148 NHSENATAKDIAPTL---TLYVG---KKQLVEIEKVVLHPNY--SQVDIGLIKLKQKVSV 199
            H    T    + T+   ++ VG   K+    + K+V+HP Y  +  D+ L+KL  +V+ 
Sbjct: 68  -HCIQPTWTTFSYTVWLGSITVGDSRKRVKYYVSKIVIHPKYQDTTADVALLKLSSQVTF 126

Query: 200 NERVMPICLPS-KDYAEVGRVGYVSGWGR---NANFKFTDHLKYVMLPVADQDQCIRHYE 255
              ++PICLPS      +    +V+GWG+   +++  +   L+   +P+ D+  C + Y 
Sbjct: 127 TSAILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLY- 185

Query: 256 GSTVPEKKTPKSPVGV-----QPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTW 310
                      +P+G+     +P++ E   CAG ++  +D+C GD+G   + H   +  W
Sbjct: 186 -----------NPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCH--IDGVW 232

Query: 311 YATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIA 345
             TG++S+   C  +  GVY  V   Q W+  TI+
Sbjct: 233 IQTGVVSWGLECGKSLPGVYTNVIYYQKWINATIS 267


>gi|4503625 coagulation factor X preproprotein [Homo sapiens]
          Length = 488

 Score =  112 bits (281), Expect = 4e-25
 Identities = 75/264 (28%), Positives = 129/264 (48%), Gaps = 32/264 (12%)

Query: 92  KPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLT-TGATLINEQWLLTTAKNLFLNHS 150
           +P+   N + RI+GG     G  PWQA +++  N    G T+++E ++LT A  L+    
Sbjct: 224 QPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKR 283

Query: 151 ENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQ----VDIGLIKLKQKVSVNERVMPI 206
                 D         G + + E+E V+ H  +++     DI +++LK  ++    V P 
Sbjct: 284 FKVRVGD--RNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPA 341

Query: 207 CLPSKDYAE----VGRVGYVSGWGR-NANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPE 261
           CLP +D+AE      + G VSG+GR +   + +  LK + +P  D++ C           
Sbjct: 342 CLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSC----------- 390

Query: 262 KKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKS 321
                  +    I+ ++ FCAG    QED C GD+G         +DT++ TGI+S+ + 
Sbjct: 391 ------KLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTR--FKDTYFVTGIVSWGEG 442

Query: 322 CA-VAEYGVYVKVTSIQDWVQKTI 344
           CA   +YG+Y KVT+   W+ +++
Sbjct: 443 CARKGKYGIYTKVTAFLKWIDRSM 466


>gi|4503649 coagulation factor IX preproprotein [Homo sapiens]
          Length = 461

 Score =  106 bits (265), Expect = 3e-23
 Identities = 72/265 (27%), Positives = 124/265 (46%), Gaps = 50/265 (18%)

Query: 98  NPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKD 157
           N   R++GG     G FPWQ  +    +   G +++NE+W++T A      H      K 
Sbjct: 222 NDFTRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAA------HCVETGVK- 274

Query: 158 IAPTLTLYVGKKQLVEIE---------KVVLHPNYSQV------DIGLIKLKQKVSVNER 202
               +T+  G+  + E E         +++ H NY+        DI L++L + + +N  
Sbjct: 275 ----ITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSY 330

Query: 203 VMPICLPSKDYAEV---GRVGYVSGWGRNAN-FKFTDHLKYVMLPVADQDQCIRHYEGST 258
           V PIC+  K+Y  +      GYVSGWGR  +  +    L+Y+ +P+ D+  C+R      
Sbjct: 331 VTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLR------ 384

Query: 259 VPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF 318
                        +  +  + FCAG  +   D+C GD+G         E T + TGI+S+
Sbjct: 385 -----------STKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTE--VEGTSFLTGIISW 431

Query: 319 DKSCAV-AEYGVYVKVTSIQDWVQK 342
            + CA+  +YG+Y KV+   +W+++
Sbjct: 432 GEECAMKGKYGIYTKVSRYVNWIKE 456


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  105 bits (261), Expect = 8e-23
 Identities = 76/284 (26%), Positives = 131/284 (46%), Gaps = 42/284 (14%)

Query: 80  GDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLL 139
           G +  +    CG+P+     + R++GG    +G +PWQ  +  + +   G +LI EQW+L
Sbjct: 16  GSQRAKAATACGRPRM----LNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVL 71

Query: 140 TTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVE---------IEKVVLHPNY----SQV 186
           T A + F N SE +  +       + +G +QLV+         + +V  +P Y    S  
Sbjct: 72  TAA-HCFRNTSETSLYQ-------VLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSA 123

Query: 187 DIGLIKLKQKVSVNERVMPICLPSKDYA-EVGRVGYVSGWGRNANFKFTDH---LKYVML 242
           D+ L++L+  V     ++P+CLP      E G   +V+GWG  +          L+ + +
Sbjct: 124 DVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAV 183

Query: 243 PVADQDQCIRHYEGSTVPEKKTPKSPVGVQP-ILNEHTFCAGMSKYQEDTCYGDAGSAFA 301
           P+ D  +C   Y   T           G QP  +     CAG  + ++D C GD+G    
Sbjct: 184 PIIDTPKCNLLYSKDT---------EFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLV 234

Query: 302 VHDLEEDTWYATGILSFDKSCAVAEY-GVYVKVTSIQDWVQKTI 344
              L   +W   G++S+ + CA     GVY++VT+  +W+ + I
Sbjct: 235 C--LVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRII 276


>gi|4506115 protein C [Homo sapiens]
          Length = 461

 Score =  104 bits (259), Expect = 1e-22
 Identities = 75/271 (27%), Positives = 127/271 (46%), Gaps = 56/271 (20%)

Query: 102 RILGGHLDAKGSFPWQAKMV-SHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAP 160
           R++ G +  +G  PWQ  ++ S   L  GA LI+  W+LT A  +           D + 
Sbjct: 211 RLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCM-----------DESK 259

Query: 161 TLTLYVGKKQL---------VEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPIC 207
            L + +G+  L         ++I++V +HPNYS+     DI L+ L Q  ++++ ++PIC
Sbjct: 260 KLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPIC 319

Query: 208 LPSKDYAE-----VGRVGYVSGWG------RNANFKFTDHLKYVMLPVADQDQCIRHYEG 256
           LP    AE      G+   V+GWG      + A    T  L ++ +PV   ++C      
Sbjct: 320 LPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNEC------ 373

Query: 257 STVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGIL 316
           S V           +  +++E+  CAG+   ++D C GD+G           TW+  G++
Sbjct: 374 SEV-----------MSNMVSENMLCAGILGDRQDACEGDSGGPMVAS--FHGTWFLVGLV 420

Query: 317 SFDKSCAVA-EYGVYVKVTSIQDWVQKTIAE 346
           S+ + C +   YGVY KV+   DW+   I +
Sbjct: 421 SWGEGCGLLHNYGVYTKVSRYLDWIHGHIRD 451


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  102 bits (253), Expect = 7e-22
 Identities = 78/270 (28%), Positives = 123/270 (45%), Gaps = 26/270 (9%)

Query: 87  EAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLF 146
           EA CG       P  RI GG     G +PWQ  +        G +L++EQW+L+ A    
Sbjct: 34  EAPCG-----VAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFP 88

Query: 147 LNHSENA-TAKDIAPTLTLYVGKKQLVEIEKVVLHPNY----SQVDIGLIKLKQKVSVNE 201
             H + A   K  A  L  Y    ++  ++ ++ HP+Y    SQ DI L++L + ++ + 
Sbjct: 89  SEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSR 148

Query: 202 RVMPICLPSKDYA-EVGRVGYVSGWGR---NANFKFTDHLKYVMLPVADQDQCIRHYEGS 257
            + PICLP+ + +   G    V+GWG    + +      L+ + +P+  ++ C   Y   
Sbjct: 149 YIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNID 208

Query: 258 TVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILS 317
             PE+     P  VQ    E   CAG  +  +D C GD+G   +     E  WY TGI+S
Sbjct: 209 AKPEE-----PHFVQ----EDMVCAGYVEGGKDACQGDSGGPLSCP--VEGLWYLTGIVS 257

Query: 318 FDKSCAVAEY-GVYVKVTSIQDWVQKTIAE 346
           +  +C      GVY   +S   W+Q  + E
Sbjct: 258 WGDACGARNRPGVYTLASSYASWIQSKVTE 287


>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
          Length = 352

 Score =  101 bits (251), Expect = 1e-21
 Identities = 64/250 (25%), Positives = 111/250 (44%), Gaps = 28/250 (11%)

Query: 102 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPT 161
           RI GG     G FPWQ  + +      G +++N+ W+LT A  L+           +  T
Sbjct: 67  RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGT 126

Query: 162 LTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSKDYAEVG 217
             L     ++ E+  ++LH ++ +     DI L+ L   + +++  +PICLP++      
Sbjct: 127 NDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATW 186

Query: 218 RVGYVSGWGR----NANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQP 273
           R  +V+GWG+    + N   TD +K  M+ + D ++C + +                  P
Sbjct: 187 RECWVAGWGQTNAADKNSVKTDLMKAPMV-IMDWEECSKMF------------------P 227

Query: 274 ILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEY-GVYVK 332
            L ++  CAG      D C GD+G          + WY  GI+S+ KSC      G+Y  
Sbjct: 228 KLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTS 287

Query: 333 VTSIQDWVQK 342
           + +   W++K
Sbjct: 288 LVNYNLWIEK 297


>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
          Length = 622

 Score = 99.8 bits (247), Expect = 3e-21
 Identities = 78/276 (28%), Positives = 127/276 (46%), Gaps = 54/276 (19%)

Query: 102 RILGGHLDAKGSFPWQAKMV--SHHNLTTGATLINEQWLLTTAKNL-FLNHSENATAKDI 158
           RI+ G     G  PWQ  +   S   L  GA+LI+++W+LT A  L +    +N T  D 
Sbjct: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND- 421

Query: 159 APTLTLYVGK----------KQLVEIEKVVLHPNYS-----QVDIGLIKLKQKVSVNERV 203
              L + +GK          +++  +EK+ +HP Y+       DI L+KLK+ V+ ++ +
Sbjct: 422 ---LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYI 478

Query: 204 MPICLPSKDYA----EVGRVGYVSGWGR-------NANFKFTDHLKYVMLPVADQDQCIR 252
            P+CLP ++ A    + G  G V+GWG        N        L+ V LP+ ++  C  
Sbjct: 479 HPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVC-- 536

Query: 253 HYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQE---DTCYGDAGSAFAVHDLEEDT 309
                        K    ++  + ++ FCAG    +    D C GD+G  F +     + 
Sbjct: 537 -------------KDSTRIR--ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNR 581

Query: 310 WYATGILSFDKSC-AVAEYGVYVKVTSIQDWVQKTI 344
           WY  GI+S+ + C    +YG Y  V  ++ W+QK I
Sbjct: 582 WYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVI 617


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score = 99.0 bits (245), Expect = 6e-21
 Identities = 74/267 (27%), Positives = 118/267 (44%), Gaps = 31/267 (11%)

Query: 82  KLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTT 141
           KL EC A     K       R++GG   A G  PWQ  +        GAT++ ++WLL+ 
Sbjct: 488 KLQECGARPAMEKPT-----RVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSA 542

Query: 142 AKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYS----QVDIGLIKLKQKV 197
           A        E   A     +L    G    + + +VVLHP Y+      D+ +++L   +
Sbjct: 543 AHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPL 602

Query: 198 SVNERVMPICLP-SKDYAEVGRVGYVSGWG--RNANFKFTDHLKYVMLPVADQDQCIRHY 254
           + N+ + P+CLP +     VGR   +SGWG  +  N    + L+   + + DQ  C   Y
Sbjct: 603 AFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLY 662

Query: 255 EGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATG 314
             S                 L +   CAG  + + D+C GD+G   A  +     +Y  G
Sbjct: 663 NFS-----------------LTDRMICAGFLEGKVDSCQGDSGGPLACEE-APGVFYLAG 704

Query: 315 ILSFDKSCA-VAEYGVYVKVTSIQDWV 340
           I+S+   CA V + GVY ++T ++ W+
Sbjct: 705 IVSWGIGCAQVKKPGVYTRITRLKGWI 731



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 69/267 (25%), Positives = 116/267 (43%), Gaps = 34/267 (12%)

Query: 87  EAVCGKPKNPA-NPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNL 145
           EA C     PA     RI+GG   + G FPWQA +  +     GA +IN +WL++ A   
Sbjct: 186 EAHCECGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAH-- 243

Query: 146 FLNHSENATAKDIAPTLTLYVGKKQL----VEIEKVVLHPNY----SQVDIGLIKLKQKV 197
             N  ++ T K +A     Y+   +      ++ ++V HP Y    +  D+ +++L   +
Sbjct: 244 CFNEFQDPT-KWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPL 302

Query: 198 SVNERVMPICLPSKDYA-EVGRVGYVSGWG--RNANFKFTDHLKYVMLPVADQDQCIRHY 254
                + P+CLP+  +     +   +SGWG  +       + L+   + + DQ  C   Y
Sbjct: 303 PFGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLY 362

Query: 255 EGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATG 314
             S                 L +   CAG    + D+C GD+G      +     ++  G
Sbjct: 363 GHS-----------------LTDRMVCAGYLDGKVDSCQGDSGGPLVCEE-PSGRFFLAG 404

Query: 315 ILSFDKSCAVAEY-GVYVKVTSIQDWV 340
           I+S+   CA A   GVY +VT ++DW+
Sbjct: 405 IVSWGIGCAEARRPGVYARVTRLRDWI 431



 Score = 82.0 bits (201), Expect = 7e-16
 Identities = 71/273 (26%), Positives = 114/273 (41%), Gaps = 34/273 (12%)

Query: 82   KLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKM-VSHHNLTTGATLINEQWLLT 140
            +LP+C         PA  + RI+GG    +G +PWQ  + +       GA L+ E+WLL+
Sbjct: 813  QLPDCGLA------PA-ALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLS 865

Query: 141  TAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYS----QVDIGLIKLKQK 196
             A + F  + +         T  L   + QL  + ++  HP Y+      D+ L++L   
Sbjct: 866  AA-HCFDVYGDPKQWAAFLGTPFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGP 924

Query: 197  VSVNERVMPICLPSK-DYAEVGRVGYVSGWGR-NANFKFTDHLKYVMLPVADQDQCIRHY 254
            V  +  V PICLP        G    ++GWG           L+   + +  +  C R Y
Sbjct: 925  VRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFY 984

Query: 255  EGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATG 314
                         PV +    +    CAG  +   D+C GDAG   A  +     W  TG
Sbjct: 985  -------------PVQI----SSRMLCAGFPQGGVDSCSGDAGGPLACRE-PSGRWVLTG 1026

Query: 315  ILSFDKSCAVAEY-GVYVKVTSIQDWVQKTIAE 346
            + S+   C    + GVY +V +++ W+ + I E
Sbjct: 1027 VTSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQE 1059


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 67/262 (25%), Positives = 119/262 (45%), Gaps = 40/262 (15%)

Query: 99  PVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDI 158
           P  RI+GG + ++G +PWQA +        G  LI ++W++T A + F   S  +T    
Sbjct: 573 PSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAA-HCFQEDSMASTV--- 628

Query: 159 APTLTLYVGK---------KQLVEIEKVVLHPNYSQ----VDIGLIKLKQKVSVNERVMP 205
               T+++GK         +   ++ +++LHP + +     D+ L++L   V  +  V P
Sbjct: 629 --LWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRP 686

Query: 206 ICLPSKD-YAEVGRVGYVSGWGR-NANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKK 263
           +CLP++  + E G   +++GWG        ++ L+ V + +  QD C   Y     P   
Sbjct: 687 VCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVTP--- 743

Query: 264 TPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCA 323
                            CAG  K ++D C GD+G       L    W+  G++S+   C 
Sbjct: 744 --------------RMLCAGYRKGKKDACQGDSGGPLVCKAL-SGRWFLAGLVSWGLGCG 788

Query: 324 VAEY-GVYVKVTSIQDWVQKTI 344
              Y GVY ++T +  W+Q+ +
Sbjct: 789 RPNYFGVYTRITGVISWIQQVV 810


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 72/263 (27%), Positives = 117/263 (44%), Gaps = 44/263 (16%)

Query: 102 RILGGHLDAKGSFPWQAKMVSHHNLTT-----GATLINEQWLLTTAKNLFLNHSENATAK 156
           RI+GG    +G +PWQ  +  H    T     G ++I  QW+LT A   +        + 
Sbjct: 387 RIVGGTASVRGEWPWQVTL--HTTSPTQRHLCGGSIIGNQWILTAAHCFY-----GVESP 439

Query: 157 DIAPTLTLYVGKKQLVE------IEKVVLHPNY----SQVDIGLIKLKQKVSVNERVMPI 206
            I    +  + + ++ E      ++++++H  Y    S  DI L+KL+  V+  +   PI
Sbjct: 440 KILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPI 499

Query: 207 CLPSK-DYAEVGRVGYVSGWG-RNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKT 264
           CLPSK D   +    +V+GWG R    K  + L+   +P+   ++C + Y G  +  K  
Sbjct: 500 CLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHK-- 557

Query: 265 PKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAV 324
                           CAG  +  +D C GD+G   +      + W+  GI S+ + CA 
Sbjct: 558 --------------MICAGYREGGKDACKGDSGGPLSCK--HNEVWHLVGITSWGEGCAQ 601

Query: 325 AEY-GVYVKVTSIQDWV-QKTIA 345
            E  GVY  V    DW+ +KT A
Sbjct: 602 RERPGVYTNVVEYVDWILEKTQA 624


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 70/259 (27%), Positives = 114/259 (44%), Gaps = 46/259 (17%)

Query: 101 QRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKD-IA 159
           QRILGG    +GS+PWQ  +  ++    G +LIN  W+LT A         N+  +D IA
Sbjct: 185 QRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCF----RSNSNPRDWIA 240

Query: 160 PTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLP-SKDYA 214
            +       K  + +  +++H NY       DI L++L+  V+  + +  +CLP +    
Sbjct: 241 TSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNI 300

Query: 215 EVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPI 274
             G   YV+GWG                         + Y G TVPE +  +  +    +
Sbjct: 301 PPGSTAYVTGWG------------------------AQEYAGHTVPELRQGQVRIISNDV 336

Query: 275 LN-EHTF---------CAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAV 324
            N  H++         CAG+ +   D C GD+G      D     W+  GI+S+   C +
Sbjct: 337 CNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQED-SRRLWFIVGIVSWGDQCGL 395

Query: 325 AEY-GVYVKVTSIQDWVQK 342
            +  GVY +VT+  DW+++
Sbjct: 396 PDKPGVYTRVTAYLDWIRQ 414


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 77/270 (28%), Positives = 124/270 (45%), Gaps = 28/270 (10%)

Query: 88  AVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFL 147
           A CG+P+  +    RI+GG     G +PWQA +        G +LI  QW+LT A + F 
Sbjct: 26  AACGQPRMSS----RIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAA-HCFP 80

Query: 148 NHSENATAKDIAPTLTLYVGKKQL--VEIEKVVLHPNYSQ----VDIGLIKLKQKVSVNE 201
             +  A  +     L L     +   V + +V+L P+YS+     D+ L++L++ V ++ 
Sbjct: 81  RRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSA 140

Query: 202 RVMPICLPSKD-YAEVGRVGYVSGWGR---NANFKFTDHLKYVMLPVADQDQCIRHYE-G 256
           RV P+CLP        G    V+GWG             L+ V +P+ D   C   Y  G
Sbjct: 141 RVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVG 200

Query: 257 STVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGIL 316
           + VP+          + I+   + CAG  +  +D C GD+G       L+  +W   G++
Sbjct: 201 ADVPQ---------AERIVLPGSLCAGYPQGHKDACQGDSGGPLTC--LQSGSWVLVGVV 249

Query: 317 SFDKSCAVAEY-GVYVKVTSIQDWVQKTIA 345
           S+ K CA+    GVY  V +   W+Q  ++
Sbjct: 250 SWGKGCALPNRPGVYTSVATYSPWIQARVS 279


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 76/308 (24%), Positives = 137/308 (44%), Gaps = 51/308 (16%)

Query: 55   YYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSF 114
            + KL T  DG   L   +Q +  ++  +L      CGK     +   +I+GG    +G++
Sbjct: 738  FVKLNTAPDGHLILTPSQQCLQDSL-IRLQCNHKSCGKKLAAQDITPKIVGGSNAKEGAW 796

Query: 115  PWQAKMVSHHNLTTGATLINEQWLLTTAKNLF--------------LNHSENATAKDIAP 160
            PW   +     L  GA+L++  WL++ A  ++              L+   N T+    P
Sbjct: 797  PWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVP 856

Query: 161  TLTLYVGKKQLVEIEKVVLHPNYSQ----VDIGLIKLKQKVSVNERVMPICLPSKDYA-E 215
             L           I+++V++P+Y++     DI ++ L+ KV+  + + PICLP ++    
Sbjct: 857  RL-----------IDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFP 905

Query: 216  VGRVGYVSGWGRNANFKFTDH-LKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPI 274
             GR   ++GWG       T + L+   +P+   ++C +      +PE             
Sbjct: 906  PGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQ-----MPEYN----------- 949

Query: 275  LNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEY-GVYVKV 333
            + E+  CAG  +   D+C GD+G        E + W+  G+ SF   CA+    GVY +V
Sbjct: 950  ITENMICAGYEEGGIDSCQGDSGGPLMCQ--ENNRWFLAGVTSFGYKCALPNRPGVYARV 1007

Query: 334  TSIQDWVQ 341
            +   +W+Q
Sbjct: 1008 SRFTEWIQ 1015


>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
          Length = 423

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 68/246 (27%), Positives = 105/246 (42%), Gaps = 26/246 (10%)

Query: 102 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPT 161
           RI+GG    +G +PWQA +    +   GATLIN  WL++ A       +          T
Sbjct: 191 RIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVT 250

Query: 162 LTLYVGKKQLVEIEKVVLHPNYSQ----VDIGLIKLKQKVSVNERVMPICLPSKDYA-EV 216
           +     K+ L    ++++H  Y       DI L +L   V     V  +CLP   Y  + 
Sbjct: 251 IKPSKMKRGL---RRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQP 307

Query: 217 GRVGYVSGWGRNANFKFT-DHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPIL 275
           G V +V+G+G   N  ++ +HL+   + + D   C                 P      +
Sbjct: 308 GDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTC---------------NEPQAYNDAI 352

Query: 276 NEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEY-GVYVKVT 334
                CAG  + + D C GD+G      D   D WY  GI+S+   CA     GVY +VT
Sbjct: 353 TPRMLCAGSLEGKTDACQGDSGGPLVSSDAR-DIWYLAGIVSWGDECAKPNKPGVYTRVT 411

Query: 335 SIQDWV 340
           +++DW+
Sbjct: 412 ALRDWI 417


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 68/258 (26%), Positives = 117/258 (45%), Gaps = 31/258 (12%)

Query: 102 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPT 161
           RI+GG   A G +PWQA +      T G +++  +W++T A  +        ++  +   
Sbjct: 217 RIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAG 276

Query: 162 LTLY--VGKKQLVEIEKVVLHPNYS----QVDIGLIKLKQKVSVNERVMPICLPSKD-YA 214
           L  +  V   Q   +E+++ HP YS      D+ L++L+  ++ ++ V  +CLP+K+ + 
Sbjct: 277 LVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHF 336

Query: 215 EVGRVGYVSGWGRN--ANFKFTDHLKYVMLPVADQDQCIRH--YEGSTVPEKKTPKSPVG 270
             G   +VSGWG    ++   +D L+  ++P+     C     Y G+  P          
Sbjct: 337 PKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTP---------- 386

Query: 271 VQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEY-GV 329
                     CAG    + D C GD+G      D   DTW   G++S+ + CA   + GV
Sbjct: 387 -------RMLCAGYLDGRADACQGDSGGPLVCPD--GDTWRLVGVVSWGRGCAEPNHPGV 437

Query: 330 YVKVTSIQDWVQKTIAEN 347
           Y KV    DW+  T  ++
Sbjct: 438 YAKVAEFLDWIHDTAQDS 455


>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
          Length = 423

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 68/246 (27%), Positives = 105/246 (42%), Gaps = 26/246 (10%)

Query: 102 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPT 161
           RI+GG    +G +PWQA +    +   GATLIN  WL++ A       +          T
Sbjct: 191 RIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVT 250

Query: 162 LTLYVGKKQLVEIEKVVLHPNYSQ----VDIGLIKLKQKVSVNERVMPICLPSKDYA-EV 216
           +     K+ L    ++++H  Y       DI L +L   V     V  +CLP   Y  + 
Sbjct: 251 IKPSKMKRGL---RRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQP 307

Query: 217 GRVGYVSGWGRNANFKFT-DHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPIL 275
           G V +V+G+G   N  ++ +HL+   + + D   C                 P      +
Sbjct: 308 GDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTC---------------NEPQAYNDAI 352

Query: 276 NEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEY-GVYVKVT 334
                CAG  + + D C GD+G      D   D WY  GI+S+   CA     GVY +VT
Sbjct: 353 TPRMLCAGSLEGKTDACQGDSGGPLVSSDAR-DIWYLAGIVSWGDECAKPNKPGVYTRVT 411

Query: 335 SIQDWV 340
           +++DW+
Sbjct: 412 ALRDWI 417


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 77/275 (28%), Positives = 123/275 (44%), Gaps = 31/275 (11%)

Query: 83  LPECEAV---CGKPK-NPANPVQRILGGHLDAKGSFPWQAKMVSHHNLT-TGATLINEQW 137
           +P+C A    CGKP+  P     R++GG +    S+PWQ  + +   +   G TLI+ +W
Sbjct: 557 VPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEW 616

Query: 138 LLTTAKNLFLNHSENATAKDIAPTLTLYVGKK---QLVEIEKVVLHPNYSQVDIGLIKLK 194
           +LT A    L  S   ++  +       V  +   Q +E+ ++ L P  ++ DI L+KL 
Sbjct: 617 VLTAAH--CLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP--TRKDIALLKLS 672

Query: 195 QKVSVNERVMPICLPSKDYAEVGRVG-YVSGWGRNANFKFTDHLKYVMLPVADQDQCIRH 253
               + ++V+P CLPS +Y    R   +++GWG          LK   LPV +   C R 
Sbjct: 673 SPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNR- 731

Query: 254 YEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYAT 313
           YE      + T                CAG      D+C GD+G        E+D +   
Sbjct: 732 YEFLNGRVQST--------------ELCAGHLAGGTDSCQGDSGGPLVC--FEKDKYILQ 775

Query: 314 GILSFDKSCA-VAEYGVYVKVTSIQDWVQKTIAEN 347
           G+ S+   CA   + GVYV+V+    W++  +  N
Sbjct: 776 GVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN 810


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,983,655
Number of Sequences: 37866
Number of extensions: 649356
Number of successful extensions: 1824
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 1355
Number of HSP's gapped (non-prelim): 202
length of query: 347
length of database: 18,247,518
effective HSP length: 103
effective length of query: 244
effective length of database: 14,347,320
effective search space: 3500746080
effective search space used: 3500746080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.