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Search of human proteins with 186700623
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
sapiens]
(729 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 1485 0.0
gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo sapi... 735 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 80 5e-15
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 78 3e-14
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 70 9e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 70 9e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 70 9e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 70 9e-12
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 69 2e-11
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 69 2e-11
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 69 2e-11
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 69 2e-11
gi|112421108 capicua homolog [Homo sapiens] 67 4e-11
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 67 8e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni... 66 1e-10
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 65 2e-10
gi|153792074 proline rich 12 [Homo sapiens] 65 2e-10
gi|55741677 SET domain containing 1A [Homo sapiens] 65 3e-10
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 65 3e-10
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 65 3e-10
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 65 3e-10
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 65 3e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 5e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 5e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is... 64 5e-10
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 64 5e-10
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 64 6e-10
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 62 2e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 62 2e-09
gi|149944516 tet oncogene family member 3 [Homo sapiens] 61 3e-09
>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
sapiens]
Length = 729
Score = 1485 bits (3844), Expect = 0.0
Identities = 729/729 (100%), Positives = 729/729 (100%)
Query: 1 MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60
MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW
Sbjct: 1 MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60
Query: 61 HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120
HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP
Sbjct: 61 HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120
Query: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180
QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM
Sbjct: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180
Query: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240
GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL
Sbjct: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240
Query: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300
RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP
Sbjct: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300
Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360
VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR
Sbjct: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360
Query: 361 LFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKA 420
LFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKA
Sbjct: 361 LFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKA 420
Query: 421 AQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAP 480
AQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAP
Sbjct: 421 AQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAP 480
Query: 481 TKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPA 540
TKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPA
Sbjct: 481 TKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPA 540
Query: 541 EMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTD 600
EMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTD
Sbjct: 541 EMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTD 600
Query: 601 EDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKK 660
EDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKK
Sbjct: 601 EDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKK 660
Query: 661 GKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEAFLGGGAPGGRH 720
GKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEAFLGGGAPGGRH
Sbjct: 661 GKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEAFLGGGAPGGRH 720
Query: 721 PGGGDYEEL 729
PGGGDYEEL
Sbjct: 721 PGGGDYEEL 729
>gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo
sapiens]
Length = 520
Score = 735 bits (1897), Expect = 0.0
Identities = 360/360 (100%), Positives = 360/360 (100%)
Query: 1 MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60
MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW
Sbjct: 1 MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60
Query: 61 HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120
HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP
Sbjct: 61 HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120
Query: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180
QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM
Sbjct: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180
Query: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240
GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL
Sbjct: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240
Query: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300
RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP
Sbjct: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300
Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360
VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR
Sbjct: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 80.5 bits (197), Expect = 5e-15
Identities = 118/497 (23%), Positives = 189/497 (38%), Gaps = 59/497 (11%)
Query: 235 QRETLL--RQLETNQLDMDATLEELSVQQETED-QNYGIFLEMMEARSRGHASPLAANGQ 291
++ET++ Q E Q+ + T EE +E E + G E E SP A
Sbjct: 451 EKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAA 510
Query: 292 SPSPGSQSPVV-----PAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPA 346
SP ++SPV PA A S +P +P PP P
Sbjct: 511 SPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKE 570
Query: 347 CPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLED 406
+PA +S SPA E A P E A+ P +S P +S E
Sbjct: 571 EAKSPAEVKSPEK---AKSPAKEEAKSPAE----AKSPEKAKS-----PVKEEAKSPAEA 618
Query: 407 TTPARDEKKVGAKA-AQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQ 465
+P ++E K A+ + + + S + +P A + + + + P+ A +
Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE 678
Query: 466 DITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIP--ASKPRRGTAPTRTAAPPWPGG 523
S +AE +P K +P ++ PE S + A P + +P + A
Sbjct: 679 KA--KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT---- 732
Query: 524 VSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQ 583
PEK S P + E E+A S E A+ L + P+ ++ +
Sbjct: 733 ------PEKAKS---PVKEEAKSPEKAKSPEK-------AKTLD--VKSPEAKTPAKEEA 774
Query: 584 RR-ADDFPVRDDPSDVTDEDEGPAEPPPPPK--LPLPAFRLKNDSDLFGLGLEEAGPKE- 639
R AD FP + S V +E + P + P K P + ++ EE P+E
Sbjct: 775 RSPADKFPEKAK-SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833
Query: 640 -------SSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQ 692
+EE K TP E+KK KK + +++A K K + KK E+ KE + +
Sbjct: 834 KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893
Query: 693 QRPPRSRERTAADELEA 709
+ +++ E EA
Sbjct: 894 KEEAEDKKKVPTPEKEA 910
Score = 56.2 bits (134), Expect = 1e-07
Identities = 96/448 (21%), Positives = 168/448 (37%), Gaps = 46/448 (10%)
Query: 276 EARSRGHA-SPLAANGQSP----SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPP 330
EA+S A SP+ +SP SP + PA S + T + A +P
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
Query: 331 SSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSV 390
P P A +P +S + EA P P E + +
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEKAKSPVK--------AEAKSPEKAKSPVKEEAKSPEKA 708
Query: 391 EDFVPDDRLDRSFLEDTTPARDEKKVGAKA---AQQDSDSDGEALGGNPMVAGFQDDVDL 447
+ V ++ +S + +P ++E K KA ++++ S +A +
Sbjct: 709 KSPVKEEA--KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA 766
Query: 448 EDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPR 507
+ + PA P + S + EV +P K +P + PE + P+
Sbjct: 767 KTPAKEEARSPADKFPEK---AKSPVKEEVKSPEKAKSPLKEDAKAPEKEI-------PK 816
Query: 508 RGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPA-----EMEPGKGEQASSSESDPEGPIA 562
+ + P V V+ P+K + PA E + K E+A E+ P
Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK--PKV 874
Query: 563 AQMLSFVMDDPDFESEGSDTQRRADD-----FPVRDDPSDV-TDEDEGPAEPPPPPKLPL 616
+ ++ P ES+ + A+D P ++ P+ V ED P E K
Sbjct: 875 EEKKEPAVEKPK-ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP 933
Query: 617 PAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHK 676
+ K S +EA P++ + ++ K P +EK K + K KE+++ +K+ SK K
Sbjct: 934 DDAKAKEPSK--PAEKKEAAPEKKDTKEEKAKKP-EEKPKTEAKAKEDDKTLSKEPSKPK 990
Query: 677 KSKDKEEGKEERRRRQQRPPRSRERTAA 704
K E+ ++ + P ++ E AA
Sbjct: 991 AEK-AEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 43.9 bits (102), Expect = 5e-04
Identities = 78/397 (19%), Positives = 139/397 (35%), Gaps = 59/397 (14%)
Query: 276 EARSRGHA-SPLAANGQSP----SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPP 330
EA+S A SP+ A +SP SP + P A S +P+ A A
Sbjct: 673 EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 732
Query: 331 SSVPPVPPSEALPPPACPSAPAPRRSI-ISRLFGTSPATEAAPPPPEPVPA-AEGPAT-- 386
P E P +P +++ + +PA E A P + P A+ P
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEE 792
Query: 387 VQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVD 446
V+S E + D E P ++E K K ++ + V
Sbjct: 793 VKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQE------------------VK 834
Query: 447 LEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTK-GPAPAPQQCSEPETKWSSIPASK 505
+++ P+ + A P + S++E AP K P P ++ EP + +
Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEE---APKKEAPKPKVEEKKEPAVEKPKESKVE 891
Query: 506 PRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQM 565
++ A + P + E + +P + E K E + +P P +
Sbjct: 892 AKKEEAEDKKKVPTPEKEAPAKV--EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949
Query: 566 LSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDS 625
+ P+ + + ++ ++ P + + ++D+ ++ P PK
Sbjct: 950 AA-----PEKKDTKEEKAKKPEEKPKTE--AKAKEDDKTLSKEPSKPKA----------- 991
Query: 626 DLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGK 662
E K SS + K+ K P K + K KGK
Sbjct: 992 --------EKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 31.6 bits (70), Expect = 2.7
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 8/102 (7%)
Query: 608 PPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEK 667
P PK+P + +K S+ E+ E SE+ E+ + ++ EEEEK
Sbjct: 423 PEGLPKIPSVSTHIKVKSE------EKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEK 476
Query: 668 AAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEA 709
AK++ ++ +EE E + PP E A+ E EA
Sbjct: 477 EAKEEEGKEEEGGEEEEAEGGEEETKSPP--AEEAASPEKEA 516
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 77.8 bits (190), Expect = 3e-14
Identities = 124/502 (24%), Positives = 180/502 (35%), Gaps = 99/502 (19%)
Query: 292 SPSPGSQSPVVPAG-AVSTGSSSPGTPQPAPQLPLNA---APPSSVPPVPPSEALPPPAC 347
SP S P + TG P P PAP ++ +P SS P PP PPPA
Sbjct: 161 SPQSNSSRPTCARHLTLGTGDGGPAPP-PAPSSASSSPSPSPSSSSPSPPPPP--PPPAP 217
Query: 348 PSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDT 407
P+ PAPR I P EA PPP P Q + F P S
Sbjct: 218 PAPPAPRFDIYDPF---HPTDEAYSPPPAP---------EQKYDPFEPTGSNPSSSAGTP 265
Query: 408 TPARDEKKVGAKAAQQDSDSDGEALGG-----NPMVAGFQDDVDL------EDQPR---- 452
+P +E++ + +++ + + E L + +AG DD L ++ PR
Sbjct: 266 SPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQ 325
Query: 453 GSPPLPA-GPVPSQDIT------------LSSEEEA------EVAAPTKGPAPAPQQCSE 493
+ P PA G P D T + +E EA V T G A P
Sbjct: 326 PTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLP 385
Query: 494 P---ETKWSSI--PASKPRRGTA---PTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEP- 544
P E + I P +PR + P AA P P + P + +PPA P
Sbjct: 386 PGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASAT---PTAQPLPQPPAPRAPE 442
Query: 545 GKGEQASSSESDPEGPIAAQMLSFVMDDPDFESE--GSDTQRRADDFPVRDDPSDVTDED 602
G + +ESD EG + + P +S G D +R+ +
Sbjct: 443 GDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKI----LTQRRERYRQRS 498
Query: 603 EGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTP-------SKEKK 655
PA P P P R K+ + G EA SS G + P SK+ +
Sbjct: 499 PSPAPAPAPAAAAGPPTRKKSRRERKRSG--EAKEAASSSSGTQPAPPAPASPWDSKKHR 556
Query: 656 KKKKKGKEEEEKAAKKKSKHK----------KSKDKEEG---------KEERRRRQQRPP 696
+ +K +A+++S+ + +S D+ G K RRRR PP
Sbjct: 557 SRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPP 616
Query: 697 RSRERTAADELEAFLGGGAPGG 718
+ +++ E G GG
Sbjct: 617 PATSSSSSSRRERHRGKHRDGG 638
Score = 42.4 bits (98), Expect = 0.002
Identities = 105/469 (22%), Positives = 160/469 (34%), Gaps = 65/469 (13%)
Query: 278 RSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP 337
R R +S A + +P S P P + +GSSS + + ++ L + +
Sbjct: 786 RDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGV 845
Query: 338 PSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVP---AAEGPATVQSVEDFV 394
S PA +A A SI + + P E P A P + + + V
Sbjct: 846 SSTT---PAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKV 902
Query: 395 PDD---RLDRSFLEDTTPARDEKKVGA-------------KAAQQDSDSDGEALGGNPMV 438
+ + T P++ KKV + K ++ DS S G
Sbjct: 903 KAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEET 962
Query: 439 AGFQDD----VDLEDQPRGSPPLPAGPVPSQDITLSSE--------EEAEVAAPTKGPAP 486
+ ++ V P+ +PP PA SQ + S + EEA A +G A
Sbjct: 963 SWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAE 1022
Query: 487 APQQCSEPETKWSSI----PASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRP---P 539
++ E E + PA+ TA + P G + +G E ++R P
Sbjct: 1023 EEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQLP 1082
Query: 540 AEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSD---TQRRADDFPVRDDPS 596
P + + G +A L F M++ + S Q R PS
Sbjct: 1083 TLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRKPPS 1142
Query: 597 DVTDEDEGPAEPPPPPKLPLP----AFRLKNDSDLFGLGLEEAGPK-----------ESS 641
+ G P P L LP ++ L L G G P SS
Sbjct: 1143 SL-----GMTPAPVPTSLGLPPGPSSYLLPGSLPLGGCGSTPPTPTGLAATSDKREGSSS 1197
Query: 642 EEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRR 690
EG+ G T KK ++ EE K A K KK KEE K+ R+
Sbjct: 1198 SEGR-GDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRK 1245
Score = 37.4 bits (85), Expect = 0.050
Identities = 96/459 (20%), Positives = 153/459 (33%), Gaps = 88/459 (19%)
Query: 305 GAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEA----LPPPACPSAPAPRRSIISR 360
G +G S P PAP PPS ++ PP+ I R
Sbjct: 651 GEKRSGDGSEKAPAPAP-------PPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKR 703
Query: 361 LFGTSPATEAAPPPPEPVPAAEGPATV-QSVEDFVPDDRLDRSFLEDTTPARDEKKVGAK 419
++ P P P PA+ V E ++R +S +D ++ GA
Sbjct: 704 TITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKS------SQKDRRRSGAA 757
Query: 420 AAQQDSDSDG---EALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAE 476
++ S G +AL G G +D D+ R A P P + S
Sbjct: 758 SSSSSSREKGSRRKALDG-----GDRDRDRDRDRDRDRSSKKARP-PKESAPSSGPPPKP 811
Query: 477 VAAPTKGPAPAPQQCSEPETKWSSIPASKPRRG---TAPTRTAAPPWPGGVSVRTGP--E 531
+ G + + CS + K S A R G T P + AA G + V+ E
Sbjct: 812 PVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRE 871
Query: 532 KRSSTRPPAEMEPGKGEQASSSESDPEGP-IAAQMLSFVMDDPDFESEGSDTQRRA---- 586
RS P E P + +A+ + P+ + A+ + +++ S T+++
Sbjct: 872 SRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGG 931
Query: 587 ------DDFPVRDDPSDVTDEDEG------------------PAEPPPPPKLPLPAFRLK 622
++ +D + G P+ PPP P PA
Sbjct: 932 GSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPD 991
Query: 623 NDSDLFGLGLEEAG--PKESSEE-GKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSK 679
+ + E P+E++EE G G G EEEE+ +
Sbjct: 992 SQTVDSSCKTPEVSFLPEEATEEAGVRG-------------GAEEEEE-----------E 1027
Query: 680 DKEEGKEERRRRQQRPPRSRERTAADELEAFLGGGAPGG 718
++EE +EE QQ + TAA G+ G
Sbjct: 1028 EEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAG 1066
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 69.7 bits (169), Expect = 9e-12
Identities = 78/348 (22%), Positives = 119/348 (34%), Gaps = 36/348 (10%)
Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343
P + P+P + P +T S+P TP +PAP P AP + P P + P
Sbjct: 270 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325
Query: 344 PPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSF 403
P P PAP T+P A P +P P + ++ P + S
Sbjct: 326 TPTTPKEPAP---TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS- 381
Query: 404 LEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVP 463
TTP A + P ++ +P PA P
Sbjct: 382 --PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 439
Query: 464 SQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPT--RTAAPPWP 521
+ + +E APT PAP +P PA + TAPT + P P
Sbjct: 440 KKPAPTTPKE----PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 495
Query: 522 GGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSD 581
++ T PEK + T P E+ P E+ + + + P + + P+ E +
Sbjct: 496 EKLAPTT-PEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAA-----PNTPKEPAP 548
Query: 582 TQRRADDFPVRDDPSDVTDEDEGPAEP------------PPPPKLPLP 617
T + +P+ T ++ P P P PK P P
Sbjct: 549 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596
Score = 59.3 bits (142), Expect = 1e-08
Identities = 82/387 (21%), Positives = 127/387 (32%), Gaps = 26/387 (6%)
Query: 292 SPSPGSQSPVVPAGAVSTGSS-SPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350
S +P +P A +T +P T + AP P AP ++ P P + P P
Sbjct: 226 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 285
Query: 351 PAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRS-FLEDTTP 409
PAP + + PA P P P T + P + + TTP
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345
Query: 410 ARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITL 469
K A P +P + P P ++
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPT-------TTKEPSPTTPKEPAPTTTKSAPT 398
Query: 470 SSEEEAEV---AAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSV 526
+++E A +APT P+P EP PA + APT T P P
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT-TPKEPAP----- 452
Query: 527 RTGPEK--RSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQR 584
T P++ ++T+ PA P + + E+ P P + P + + T
Sbjct: 453 -TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 511
Query: 585 RADDFPVRDDPSDVTDEDEGPAEP----PPPPKLPLPAFRLKNDSDLFGLGLEEAGPKES 640
++P+ T E+ P P P PK P P K + PKE+
Sbjct: 512 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKET 570
Query: 641 SEEGKEGKTPSKEKKKKKKKGKEEEEK 667
+ +G P+ K+ K+ K
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPK 597
Score = 51.6 bits (122), Expect = 3e-06
Identities = 80/406 (19%), Positives = 129/406 (31%), Gaps = 59/406 (14%)
Query: 232 LQLQRETLLRQLETNQLDMDATL---EELSVQQETEDQNYGIFLEMMEARSRGHASPLAA 288
L + +ET + ET + + E+ + +ET+ +E A+ S + A
Sbjct: 142 LTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLA 195
Query: 289 NGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP-PSEALPPPAC 347
P+P +++ + +P TP+ P S+ P P P+ P
Sbjct: 196 K---PTPKAETTTKGPALTTPKEPTPTTPK---------EPASTTPKEPTPTTIKSAPTT 243
Query: 348 PSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDT 407
P PAP + + PA P P P T + P +S T
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-----PAPTTTKS--APT 296
Query: 408 TPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDI 467
TP K A P ++ +P +P P P P+
Sbjct: 297 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP--APTTPKEPAPT--- 351
Query: 468 TLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPW----PGG 523
+ APT PAP EP + P+ + APT T + P P
Sbjct: 352 ------APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405
Query: 524 VSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQ 583
+ ++ P P EP + + P+ P P E + T+
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTK 464
Query: 584 RRADDFPVRDDPSDVTDEDEGPAEP------------PPPPKLPLP 617
+ A P +P+ T ++ P P P P+ P P
Sbjct: 465 KPAPTTP--KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 508
Score = 51.2 bits (121), Expect = 3e-06
Identities = 88/440 (20%), Positives = 136/440 (30%), Gaps = 59/440 (13%)
Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338
P + P+P + P ++P P +PAP P AP + P
Sbjct: 522 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 581
Query: 339 SEALPPPACPSAPAPRR-----------SIISRLFGTSPATEAAPPPPEPVPAAEGPATV 387
+ P P P PAP+ + + T+P A P EP P
Sbjct: 582 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 641
Query: 388 QSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDL 447
+ + P + L++ P +K + A + P ++
Sbjct: 642 TTPKGTAP------TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 695
Query: 448 EDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPR 507
+ +P P P P+ E PT P EP T S S P
Sbjct: 696 TPK-EPAPTTPKKPAPT---------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 745
Query: 508 RGTAPTRTA---APPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQ 564
PT A +P PG + +T ++T+P + PE AA
Sbjct: 746 LSAEPTPKALENSPKEPGVPTTKT----PAATKPEMTTTAKDKTTERDLRTTPETTTAA- 800
Query: 565 MLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKND 624
P E + T + + + + VT P L K
Sbjct: 801 --------PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852
Query: 625 SDLFGLGLEEAGPK-ESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEE 683
+ + E K E + + K+ T SK K +K KA KK + KK K
Sbjct: 853 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK----PTKAPKKPTSTKKPKTM-- 906
Query: 684 GKEERRRRQQRPPRSRERTA 703
R R+ + P R+ T+
Sbjct: 907 ---PRVRKPKTTPTPRKMTS 923
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 69.7 bits (169), Expect = 9e-12
Identities = 78/348 (22%), Positives = 119/348 (34%), Gaps = 36/348 (10%)
Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343
P + P+P + P +T S+P TP +PAP P AP + P P + P
Sbjct: 311 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366
Query: 344 PPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSF 403
P P PAP T+P A P +P P + ++ P + S
Sbjct: 367 TPTTPKEPAP---TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS- 422
Query: 404 LEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVP 463
TTP A + P ++ +P PA P
Sbjct: 423 --PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 480
Query: 464 SQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPT--RTAAPPWP 521
+ + +E APT PAP +P PA + TAPT + P P
Sbjct: 481 KKPAPTTPKE----PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 536
Query: 522 GGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSD 581
++ T PEK + T P E+ P E+ + + + P + + P+ E +
Sbjct: 537 EKLAPTT-PEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAA-----PNTPKEPAP 589
Query: 582 TQRRADDFPVRDDPSDVTDEDEGPAEP------------PPPPKLPLP 617
T + +P+ T ++ P P P PK P P
Sbjct: 590 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637
Score = 59.3 bits (142), Expect = 1e-08
Identities = 82/387 (21%), Positives = 127/387 (32%), Gaps = 26/387 (6%)
Query: 292 SPSPGSQSPVVPAGAVSTGSS-SPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350
S +P +P A +T +P T + AP P AP ++ P P + P P
Sbjct: 267 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 326
Query: 351 PAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRS-FLEDTTP 409
PAP + + PA P P P T + P + + TTP
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386
Query: 410 ARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITL 469
K A P +P + P P ++
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPT-------TTKEPSPTTPKEPAPTTTKSAPT 439
Query: 470 SSEEEAEV---AAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSV 526
+++E A +APT P+P EP PA + APT T P P
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT-TPKEPAP----- 493
Query: 527 RTGPEK--RSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQR 584
T P++ ++T+ PA P + + E+ P P + P + + T
Sbjct: 494 -TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552
Query: 585 RADDFPVRDDPSDVTDEDEGPAEP----PPPPKLPLPAFRLKNDSDLFGLGLEEAGPKES 640
++P+ T E+ P P P PK P P K + PKE+
Sbjct: 553 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKET 611
Query: 641 SEEGKEGKTPSKEKKKKKKKGKEEEEK 667
+ +G P+ K+ K+ K
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPK 638
Score = 51.6 bits (122), Expect = 3e-06
Identities = 80/406 (19%), Positives = 129/406 (31%), Gaps = 59/406 (14%)
Query: 232 LQLQRETLLRQLETNQLDMDATL---EELSVQQETEDQNYGIFLEMMEARSRGHASPLAA 288
L + +ET + ET + + E+ + +ET+ +E A+ S + A
Sbjct: 183 LTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLA 236
Query: 289 NGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP-PSEALPPPAC 347
P+P +++ + +P TP+ P S+ P P P+ P
Sbjct: 237 K---PTPKAETTTKGPALTTPKEPTPTTPK---------EPASTTPKEPTPTTIKSAPTT 284
Query: 348 PSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDT 407
P PAP + + PA P P P T + P +S T
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-----PAPTTTKS--APT 337
Query: 408 TPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDI 467
TP K A P ++ +P +P P P P+
Sbjct: 338 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP--APTTPKEPAPT--- 392
Query: 468 TLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPW----PGG 523
+ APT PAP EP + P+ + APT T + P P
Sbjct: 393 ------APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446
Query: 524 VSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQ 583
+ ++ P P EP + + P+ P P E + T+
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTK 505
Query: 584 RRADDFPVRDDPSDVTDEDEGPAEP------------PPPPKLPLP 617
+ A P +P+ T ++ P P P P+ P P
Sbjct: 506 KPAPTTP--KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 549
Score = 51.2 bits (121), Expect = 3e-06
Identities = 88/440 (20%), Positives = 136/440 (30%), Gaps = 59/440 (13%)
Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338
P + P+P + P ++P P +PAP P AP + P
Sbjct: 563 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 622
Query: 339 SEALPPPACPSAPAPRR-----------SIISRLFGTSPATEAAPPPPEPVPAAEGPATV 387
+ P P P PAP+ + + T+P A P EP P
Sbjct: 623 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 682
Query: 388 QSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDL 447
+ + P + L++ P +K + A + P ++
Sbjct: 683 TTPKGTAP------TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 736
Query: 448 EDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPR 507
+ +P P P P+ E PT P EP T S S P
Sbjct: 737 TPK-EPAPTTPKKPAPT---------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 786
Query: 508 RGTAPTRTA---APPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQ 564
PT A +P PG + +T ++T+P + PE AA
Sbjct: 787 LSAEPTPKALENSPKEPGVPTTKT----PAATKPEMTTTAKDKTTERDLRTTPETTTAA- 841
Query: 565 MLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKND 624
P E + T + + + + VT P L K
Sbjct: 842 --------PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893
Query: 625 SDLFGLGLEEAGPK-ESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEE 683
+ + E K E + + K+ T SK K +K KA KK + KK K
Sbjct: 894 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK----PTKAPKKPTSTKKPKTM-- 947
Query: 684 GKEERRRRQQRPPRSRERTA 703
R R+ + P R+ T+
Sbjct: 948 ---PRVRKPKTTPTPRKMTS 964
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 69.7 bits (169), Expect = 9e-12
Identities = 78/348 (22%), Positives = 119/348 (34%), Gaps = 36/348 (10%)
Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343
P + P+P + P +T S+P TP +PAP P AP + P P + P
Sbjct: 363 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418
Query: 344 PPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSF 403
P P PAP T+P A P +P P + ++ P + S
Sbjct: 419 TPTTPKEPAP---TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS- 474
Query: 404 LEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVP 463
TTP A + P ++ +P PA P
Sbjct: 475 --PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 532
Query: 464 SQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPT--RTAAPPWP 521
+ + +E APT PAP +P PA + TAPT + P P
Sbjct: 533 KKPAPTTPKE----PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 588
Query: 522 GGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSD 581
++ T PEK + T P E+ P E+ + + + P + + P+ E +
Sbjct: 589 EKLAPTT-PEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAA-----PNTPKEPAP 641
Query: 582 TQRRADDFPVRDDPSDVTDEDEGPAEP------------PPPPKLPLP 617
T + +P+ T ++ P P P PK P P
Sbjct: 642 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689
Score = 59.3 bits (142), Expect = 1e-08
Identities = 82/387 (21%), Positives = 127/387 (32%), Gaps = 26/387 (6%)
Query: 292 SPSPGSQSPVVPAGAVSTGSS-SPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350
S +P +P A +T +P T + AP P AP ++ P P + P P
Sbjct: 319 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 378
Query: 351 PAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRS-FLEDTTP 409
PAP + + PA P P P T + P + + TTP
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438
Query: 410 ARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITL 469
K A P +P + P P ++
Sbjct: 439 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPT-------TTKEPSPTTPKEPAPTTTKSAPT 491
Query: 470 SSEEEAEV---AAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSV 526
+++E A +APT P+P EP PA + APT T P P
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT-TPKEPAP----- 545
Query: 527 RTGPEK--RSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQR 584
T P++ ++T+ PA P + + E+ P P + P + + T
Sbjct: 546 -TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 604
Query: 585 RADDFPVRDDPSDVTDEDEGPAEP----PPPPKLPLPAFRLKNDSDLFGLGLEEAGPKES 640
++P+ T E+ P P P PK P P K + PKE+
Sbjct: 605 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKET 663
Query: 641 SEEGKEGKTPSKEKKKKKKKGKEEEEK 667
+ +G P+ K+ K+ K
Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKKPAPK 690
Score = 51.6 bits (122), Expect = 3e-06
Identities = 80/406 (19%), Positives = 129/406 (31%), Gaps = 59/406 (14%)
Query: 232 LQLQRETLLRQLETNQLDMDATL---EELSVQQETEDQNYGIFLEMMEARSRGHASPLAA 288
L + +ET + ET + + E+ + +ET+ +E A+ S + A
Sbjct: 235 LTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLA 288
Query: 289 NGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP-PSEALPPPAC 347
P+P +++ + +P TP+ P S+ P P P+ P
Sbjct: 289 K---PTPKAETTTKGPALTTPKEPTPTTPK---------EPASTTPKEPTPTTIKSAPTT 336
Query: 348 PSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDT 407
P PAP + + PA P P P T + P +S T
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-----PAPTTTKS--APT 389
Query: 408 TPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDI 467
TP K A P ++ +P +P P P P+
Sbjct: 390 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP--APTTPKEPAPT--- 444
Query: 468 TLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPW----PGG 523
+ APT PAP EP + P+ + APT T + P P
Sbjct: 445 ------APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498
Query: 524 VSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQ 583
+ ++ P P EP + + P+ P P E + T+
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTK 557
Query: 584 RRADDFPVRDDPSDVTDEDEGPAEP------------PPPPKLPLP 617
+ A P +P+ T ++ P P P P+ P P
Sbjct: 558 KPAPTTP--KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 601
Score = 51.2 bits (121), Expect = 3e-06
Identities = 88/440 (20%), Positives = 136/440 (30%), Gaps = 59/440 (13%)
Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338
P + P+P + P ++P P +PAP P AP + P
Sbjct: 615 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 674
Query: 339 SEALPPPACPSAPAPRR-----------SIISRLFGTSPATEAAPPPPEPVPAAEGPATV 387
+ P P P PAP+ + + T+P A P EP P
Sbjct: 675 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 734
Query: 388 QSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDL 447
+ + P + L++ P +K + A + P ++
Sbjct: 735 TTPKGTAP------TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788
Query: 448 EDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPR 507
+ +P P P P+ E PT P EP T S S P
Sbjct: 789 TPK-EPAPTTPKKPAPT---------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 838
Query: 508 RGTAPTRTA---APPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQ 564
PT A +P PG + +T ++T+P + PE AA
Sbjct: 839 LSAEPTPKALENSPKEPGVPTTKT----PAATKPEMTTTAKDKTTERDLRTTPETTTAA- 893
Query: 565 MLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKND 624
P E + T + + + + VT P L K
Sbjct: 894 --------PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 945
Query: 625 SDLFGLGLEEAGPK-ESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEE 683
+ + E K E + + K+ T SK K +K KA KK + KK K
Sbjct: 946 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK----PTKAPKKPTSTKKPKTM-- 999
Query: 684 GKEERRRRQQRPPRSRERTA 703
R R+ + P R+ T+
Sbjct: 1000 ---PRVRKPKTTPTPRKMTS 1016
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 69.7 bits (169), Expect = 9e-12
Identities = 78/348 (22%), Positives = 119/348 (34%), Gaps = 36/348 (10%)
Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343
P + P+P + P +T S+P TP +PAP P AP + P P + P
Sbjct: 404 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459
Query: 344 PPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSF 403
P P PAP T+P A P +P P + ++ P + S
Sbjct: 460 TPTTPKEPAP---TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS- 515
Query: 404 LEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVP 463
TTP A + P ++ +P PA P
Sbjct: 516 --PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 573
Query: 464 SQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPT--RTAAPPWP 521
+ + +E APT PAP +P PA + TAPT + P P
Sbjct: 574 KKPAPTTPKE----PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 629
Query: 522 GGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSD 581
++ T PEK + T P E+ P E+ + + + P + + P+ E +
Sbjct: 630 EKLAPTT-PEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAA-----PNTPKEPAP 682
Query: 582 TQRRADDFPVRDDPSDVTDEDEGPAEP------------PPPPKLPLP 617
T + +P+ T ++ P P P PK P P
Sbjct: 683 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730
Score = 59.3 bits (142), Expect = 1e-08
Identities = 82/387 (21%), Positives = 127/387 (32%), Gaps = 26/387 (6%)
Query: 292 SPSPGSQSPVVPAGAVSTGSS-SPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350
S +P +P A +T +P T + AP P AP ++ P P + P P
Sbjct: 360 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 419
Query: 351 PAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRS-FLEDTTP 409
PAP + + PA P P P T + P + + TTP
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479
Query: 410 ARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITL 469
K A P +P + P P ++
Sbjct: 480 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPT-------TTKEPSPTTPKEPAPTTTKSAPT 532
Query: 470 SSEEEAEV---AAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSV 526
+++E A +APT P+P EP PA + APT T P P
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT-TPKEPAP----- 586
Query: 527 RTGPEK--RSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQR 584
T P++ ++T+ PA P + + E+ P P + P + + T
Sbjct: 587 -TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 645
Query: 585 RADDFPVRDDPSDVTDEDEGPAEP----PPPPKLPLPAFRLKNDSDLFGLGLEEAGPKES 640
++P+ T E+ P P P PK P P K + PKE+
Sbjct: 646 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKET 704
Query: 641 SEEGKEGKTPSKEKKKKKKKGKEEEEK 667
+ +G P+ K+ K+ K
Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKKPAPK 731
Score = 51.6 bits (122), Expect = 3e-06
Identities = 80/406 (19%), Positives = 129/406 (31%), Gaps = 59/406 (14%)
Query: 232 LQLQRETLLRQLETNQLDMDATL---EELSVQQETEDQNYGIFLEMMEARSRGHASPLAA 288
L + +ET + ET + + E+ + +ET+ +E A+ S + A
Sbjct: 276 LTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLA 329
Query: 289 NGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP-PSEALPPPAC 347
P+P +++ + +P TP+ P S+ P P P+ P
Sbjct: 330 K---PTPKAETTTKGPALTTPKEPTPTTPK---------EPASTTPKEPTPTTIKSAPTT 377
Query: 348 PSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDT 407
P PAP + + PA P P P T + P +S T
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-----PAPTTTKS--APT 430
Query: 408 TPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDI 467
TP K A P ++ +P +P P P P+
Sbjct: 431 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP--APTTPKEPAPT--- 485
Query: 468 TLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPW----PGG 523
+ APT PAP EP + P+ + APT T + P P
Sbjct: 486 ------APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539
Query: 524 VSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQ 583
+ ++ P P EP + + P+ P P E + T+
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTK 598
Query: 584 RRADDFPVRDDPSDVTDEDEGPAEP------------PPPPKLPLP 617
+ A P +P+ T ++ P P P P+ P P
Sbjct: 599 KPAPTTP--KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 642
Score = 51.2 bits (121), Expect = 3e-06
Identities = 88/440 (20%), Positives = 136/440 (30%), Gaps = 59/440 (13%)
Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338
P + P+P + P ++P P +PAP P AP + P
Sbjct: 656 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 715
Query: 339 SEALPPPACPSAPAPRR-----------SIISRLFGTSPATEAAPPPPEPVPAAEGPATV 387
+ P P P PAP+ + + T+P A P EP P
Sbjct: 716 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 775
Query: 388 QSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDL 447
+ + P + L++ P +K + A + P ++
Sbjct: 776 TTPKGTAP------TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829
Query: 448 EDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPR 507
+ +P P P P+ E PT P EP T S S P
Sbjct: 830 TPK-EPAPTTPKKPAPT---------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 879
Query: 508 RGTAPTRTA---APPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQ 564
PT A +P PG + +T ++T+P + PE AA
Sbjct: 880 LSAEPTPKALENSPKEPGVPTTKT----PAATKPEMTTTAKDKTTERDLRTTPETTTAA- 934
Query: 565 MLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKND 624
P E + T + + + + VT P L K
Sbjct: 935 --------PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 986
Query: 625 SDLFGLGLEEAGPK-ESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEE 683
+ + E K E + + K+ T SK K +K KA KK + KK K
Sbjct: 987 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK----PTKAPKKPTSTKKPKTM-- 1040
Query: 684 GKEERRRRQQRPPRSRERTA 703
R R+ + P R+ T+
Sbjct: 1041 ---PRVRKPKTTPTPRKMTS 1057
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 68.9 bits (167), Expect = 2e-11
Identities = 124/559 (22%), Positives = 187/559 (33%), Gaps = 101/559 (18%)
Query: 185 VILPDDVRD------FIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRET 238
V+ PD V D DN P + SS ++ K HK P + QR +
Sbjct: 183 VVSPDHVSDSTVSARISDNSLAPVADFSYPAESSSCLDNSAAK--HKLQVKP--RNQRSS 238
Query: 239 LLRQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQ 298
+R+L + +L +L+ E E+ LE+ A + P PG
Sbjct: 239 KMRRLSSRA--QSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPP 296
Query: 299 SPVVPAG-----------------AVSTG-------SSSPGT-----PQPAPQLPLNAAP 329
+P+ P G +V G SS P T P+ AP L +
Sbjct: 297 APLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPS 356
Query: 330 PSSVPPVP-----PSEALPPPACPSAPAPRRS---------IISRLFGTSPATEAAPPPP 375
P PP P + PPA P APA ++ + S P + PP
Sbjct: 357 PPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPET 416
Query: 376 EPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGN 435
+P +E P+ E VP + E T P +++ G + + + E
Sbjct: 417 DPAATSEAPSARDGPERSVPKE------AEPTPPVLPDEEKGPPGPAPEPEREAET---E 467
Query: 436 PMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPE 495
P + + +P + P P+ P P + + AA ++GPA +P +
Sbjct: 468 PERGAGTEPERIGTEP-STAPAPSPPAPKSCL------KHRPAAASEGPAASPPLAAAES 520
Query: 496 TKWSSIPASKPRRGTAPTRTAA--PPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSS 553
P S AP R A P + R PE R + R AE+ K SS
Sbjct: 521 PPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPE-RKAERGGAELRGAKKFSVSSC 579
Query: 554 ESDPEGPI------AAQMLSFVMDDPDFESEGS--DTQRRADDFPVRDDPSDVT-----D 600
+ P + A+ L P + SE + D Q + + P + D
Sbjct: 580 RARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQD 639
Query: 601 EDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKK---- 656
+ A P P K P A G E P E + P K +
Sbjct: 640 SGDRAASPAGPRKSPQEAAAAP--------GTREPCPAAQEPAPSEDRNPFPVKLRSTSL 691
Query: 657 --KKKKGKEEEEKAAKKKS 673
K + G +E K K+ S
Sbjct: 692 SLKYRDGASQEVKGVKRYS 710
Score = 45.8 bits (107), Expect = 1e-04
Identities = 102/440 (23%), Positives = 143/440 (32%), Gaps = 109/440 (24%)
Query: 372 PPPPEPVPAAEG-PATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGE 430
PPPP +PA G A + S +D +P + S L D P KV + SDS
Sbjct: 137 PPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPG-TTIKVSVVSPDHVSDSTVS 195
Query: 431 A-LGGNPM--VAGFQDDVD-------------LEDQPRGSPPLPAGPVPSQ-------DI 467
A + N + VA F + L+ +PR + S+ D+
Sbjct: 196 ARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDL 255
Query: 468 TLSSEEE-------------------AEVAAPTKGPAPAPQQCSEP---------ETKWS 499
T + EEE + AP +GP P P P + S
Sbjct: 256 TCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHS 315
Query: 500 SI--------------PASKP------RRGTAPTRTAAPPWPGGVSVRTGPE--KRSSTR 537
S P+S+P +APT PP P GP+ K+
Sbjct: 316 SALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEA 375
Query: 538 PPA---EMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDD 594
PPA K E+ + D P + P+ + + A D P R
Sbjct: 376 PPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSV 435
Query: 595 PSD-------VTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEG 647
P + + DE++GP P P P+ R G G E P+ E
Sbjct: 436 PKEAEPTPPVLPDEEKGPPGPAPEPE------REAETEPERGAGTE---PERIGTEPSTA 486
Query: 648 KTPSKEKKK---KKKKGKEEEEKAAKKKSKHKKSKDKEEG-----------KEERRRRQQ 693
PS K K + E AA +S E G + + R +
Sbjct: 487 PAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAE 546
Query: 694 RPPRSRERTAADELEAFLGG 713
PP ER AA E +A GG
Sbjct: 547 APPAGAER-AAPERKAERGG 565
Score = 30.0 bits (66), Expect = 7.9
Identities = 34/130 (26%), Positives = 48/130 (36%), Gaps = 15/130 (11%)
Query: 303 PAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPV-----PPSEALPPPACPSAPAPRRSI 357
PA + S G + P PL++ PP P+ P + PP A P PR+
Sbjct: 734 PALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKE- 792
Query: 358 ISRLFGTSP---ATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEK 414
R P E + PP P A+G Q ++ R R D P E
Sbjct: 793 -PRTAEKRPLRRGAEKSLPPAATGPGADG----QPAPPWITVTRQKRRGTLD-QPPNQED 846
Query: 415 KVGAKAAQQD 424
K GA+ + +
Sbjct: 847 KPGARTLKSE 856
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 68.6 bits (166), Expect = 2e-11
Identities = 77/268 (28%), Positives = 104/268 (38%), Gaps = 32/268 (11%)
Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPS--EALPPP---AC 347
P+PG + S S P T P P L L PP S+ P PP EAL PP +
Sbjct: 146 PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSS 205
Query: 348 PSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSV-EDFVPDDRLDRSFLED 406
PS P P I A A PPPP P PA PA+ +V P + + +
Sbjct: 206 PSIPTPPDFIPP---APPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDV 262
Query: 407 TTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQD 466
R + A + ++ G ALG NP + + PR P PV +
Sbjct: 263 ALNGRQAEATRASPPRSPAEPKGSALGPNP-----EPHLTF---PRSFKVPPPTPVRTSS 314
Query: 467 ITLSSEEEA---EVAAPTKGPAPAPQQCSEPETKWSSIPASK--PRRGTAP-----TRTA 516
I + +EA E A K P+ P S + PAS+ P R P +
Sbjct: 315 IPVQEAQEAPRKEEGATKKAPSRLPLPPS-----FHIRPASQVYPDRAPEPDCPGELKAT 369
Query: 517 APPWPGGVSVRTGPEKRSSTRPPAEMEP 544
AP P ++ ++R+ T PPA P
Sbjct: 370 APASPRLGQSQSQADERAGTPPPAPPLP 397
Score = 52.0 bits (123), Expect = 2e-06
Identities = 73/285 (25%), Positives = 103/285 (36%), Gaps = 63/285 (22%)
Query: 295 PGSQSPVVPAG-----AVSTGSSSPGTPQPAPQLPLNAAP-PSSVPPVPPSEALPPPACP 348
PG PA + S GTP PAP LP A P P PP+PP+ A P P
Sbjct: 363 PGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPA-APPLPCAQ 421
Query: 349 SAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEG-------PATVQSVED----FVPDD 397
A P +SPA + P PP P A P+ ++ + + ++
Sbjct: 422 KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGS 481
Query: 398 RLDRSFLE-----DTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPR 452
R + FL P E K G + ++ E L P +D P
Sbjct: 482 RREDRFLSHRPGPTVAPQSKEGKKGPRLPEK------ETLLSLP----------AKDTPP 525
Query: 453 GSPPLPAGPVPSQDITLSSEEEAEVA----------APTKGPAPAPQQC-SEPETKWSSI 501
G VP + + SS E E A P P P+ +Q +E E + SS
Sbjct: 526 G--------VPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSA 577
Query: 502 --PASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEP 544
+KP G+ P + P GG G + ++P A+ P
Sbjct: 578 AEKEAKPSIGSLPPK---PRLEGGRICENGADDDKLSKPVAKNLP 619
Score = 51.6 bits (122), Expect = 3e-06
Identities = 94/409 (22%), Positives = 127/409 (31%), Gaps = 80/409 (19%)
Query: 314 PGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPP 373
P P P P ++ P S P PPS A PPP P P S+ APP
Sbjct: 143 PPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSM-------------APP 189
Query: 374 PPEPVPAAEGPATVQSVEDFVPDDRLDRSF-LEDTTPARDEKKVGAKAAQQDSDSDGEAL 432
PP + A P T+ S P D + + L P A A + G L
Sbjct: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRL 249
Query: 433 GGNPMVAGFQDDVDLE----DQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPT--KGPAP 486
V ++ DV L + R SPP P + L E + P K P P
Sbjct: 250 FPPGGVTKWKSDVALNGRQAEATRASPP--RSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307
Query: 487 APQQCSEPETKWSSIPASKPRRGT--APTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEP 544
P + S + + K T AP+R PP RP +++ P
Sbjct: 308 TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP-------------SFHIRPASQVYP 354
Query: 545 GKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEG 604
+ PE ++ + P S RA
Sbjct: 355 DRA---------PEPDCPGELKATAPASPRLGQSQSQADERA------------------ 387
Query: 605 PAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEE 664
PPP P LP PA L + L A P P +K G +
Sbjct: 388 -GTPPPAPPLPPPAPPLPPPAP----PLPPAAP----------PLPCAQKAAHPPAGFTK 432
Query: 665 EEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEAFLGG 713
K++ K K + E R P E+ +EL A+L G
Sbjct: 433 TPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEK-LRNELAAYLCG 480
Score = 46.2 bits (108), Expect = 1e-04
Identities = 72/304 (23%), Positives = 95/304 (31%), Gaps = 57/304 (18%)
Query: 333 VPPVPPSEALPPP----------ACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAE 382
+PP PP A PP PS P+ L P APPPP + A
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
Query: 383 GPATVQSVEDFVPDDRLDRS-FLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGF 441
P T+ S P D + + L P A A + G L V +
Sbjct: 199 PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258
Query: 442 QDDVDLE----DQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPT--KGPAPAPQQCSEPE 495
+ DV L + R SP P P + L E + P K P P P + S
Sbjct: 259 KSDVALNGRQAEATRASP--PRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 496 TKWSSIPASKPRRGT--APTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSS 553
+ + K T AP+R PP RP +++ P +
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPP-------------SFHIRPASQVYPDRA------ 357
Query: 554 ESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPK 613
PE ++ + P S RA P PA P PPP
Sbjct: 358 ---PEPDCPGELKATAPASPRLGQSQSQADERAGTPP--------------PAPPLPPPA 400
Query: 614 LPLP 617
PLP
Sbjct: 401 PPLP 404
Score = 38.1 bits (87), Expect = 0.029
Identities = 76/303 (25%), Positives = 102/303 (33%), Gaps = 74/303 (24%)
Query: 292 SPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351
SPS + +P + P P PAP APP+ P L P P
Sbjct: 205 SPSIPTPPDFIPPAPPLAFLAPPPPPVPAP------APPAPASPHTVGTRLFP---PGGV 255
Query: 352 APRRSIISRLFGTSPATEAAPP--PPEPVPAAEGPATVQSVEDFVPDDRLDRSF-LEDTT 408
+S ++ + AT A+PP P EP +A GP + P RSF + T
Sbjct: 256 TKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP-------NPEPHLTFPRSFKVPPPT 308
Query: 409 PAR------------DEKKVGA----------------KAAQQ-------DSDSDGEALG 433
P R K+ GA + A Q + D GE
Sbjct: 309 PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA 368
Query: 434 GNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSE 493
P D+ G+PP PA P+P L A P P P Q+ +
Sbjct: 369 TAPASPRLGQSQSQADERAGTPP-PAPPLPPPAPPL--PPPAPPLPPAAPPLPCAQKAAH 425
Query: 494 P-----ETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGE 548
P +T SS PA KP+ PP P T R P++ME + E
Sbjct: 426 PPAGFTKTPKSSSPALKPKPN--------PPSP----ENTASSAPVDWRDPSQMEKLRNE 473
Query: 549 QAS 551
A+
Sbjct: 474 LAA 476
Score = 35.8 bits (81), Expect = 0.14
Identities = 69/302 (22%), Positives = 97/302 (32%), Gaps = 45/302 (14%)
Query: 290 GQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349
GQ P SQ P+ A GS P A +LP A S+ P S C
Sbjct: 715 GQPEKPASQEVSTPSQARGEGS-----PSEATRLPTQGARSSAAFPPKTSPGGGEVPCLY 769
Query: 350 APAPRRSIISRLFGTSPATEA---APPPPEPVPAAEGPA-TVQSVEDFVPDDRLDRSFLE 405
P +S +SR T A A P EPV E P + P D L R +
Sbjct: 770 KPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT 829
Query: 406 DTTPARDEKK---VGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPV 462
R + A+ Q S G ALG + + +D + S G
Sbjct: 830 GEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTP 889
Query: 463 PSQDITLSSEEEAEVAAPTKGPAP-----------------APQQCSEPETK----WSSI 501
S + +EAE +P P ++PE + W +
Sbjct: 890 NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERV 949
Query: 502 -PASKPRRGTAPTRTAAPPWPGGVS-----------VRTGPEKRSSTRPPAEMEPGKGEQ 549
P++ P+ P ++PP P + PE + PPA G Q
Sbjct: 950 APSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQ 1009
Query: 550 AS 551
+S
Sbjct: 1010 SS 1011
Score = 33.1 bits (74), Expect = 0.94
Identities = 53/222 (23%), Positives = 80/222 (36%), Gaps = 34/222 (15%)
Query: 321 PQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPA 380
P +P A P ++PP +A PA P P+ ++ G + +A P P+ A
Sbjct: 639 PAIPPKATPEPAIPP----KATLWPATP----PKATL-----GPATPLKATSGPTTPLKA 685
Query: 381 AEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVA- 439
GPA + S +P +D+ PA +K ++ S + GE G+P A
Sbjct: 686 TSGPA-IASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGE---GSPSEAT 741
Query: 440 -----GFQDDVDLEDQPRGSPPLPAGPVP------SQDITLSSEEEAEVAAPTKGPAPAP 488
G + P+ SP G VP +LS E + +G A P
Sbjct: 742 RLPTQGARSSAAF--PPKTSP--GGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGP 797
Query: 489 QQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGP 530
+ E + +PA P P G V R P
Sbjct: 798 GEPVEVKEP-PGLPAKPPASAQPTDELLRHPVTGEVVERGSP 838
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 68.6 bits (166), Expect = 2e-11
Identities = 77/268 (28%), Positives = 104/268 (38%), Gaps = 32/268 (11%)
Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPS--EALPPP---AC 347
P+PG + S S P T P P L L PP S+ P PP EAL PP +
Sbjct: 146 PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSS 205
Query: 348 PSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSV-EDFVPDDRLDRSFLED 406
PS P P I A A PPPP P PA PA+ +V P + + +
Sbjct: 206 PSIPTPPDFIPP---APPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDV 262
Query: 407 TTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQD 466
R + A + ++ G ALG NP + + PR P PV +
Sbjct: 263 ALNGRQAEATRASPPRSPAEPKGSALGPNP-----EPHLTF---PRSFKVPPPTPVRTSS 314
Query: 467 ITLSSEEEA---EVAAPTKGPAPAPQQCSEPETKWSSIPASK--PRRGTAP-----TRTA 516
I + +EA E A K P+ P S + PAS+ P R P +
Sbjct: 315 IPVQEAQEAPRKEEGATKKAPSRLPLPPS-----FHIRPASQVYPDRAPEPDCPGELKAT 369
Query: 517 APPWPGGVSVRTGPEKRSSTRPPAEMEP 544
AP P ++ ++R+ T PPA P
Sbjct: 370 APASPRLGQSQSQADERAGTPPPAPPLP 397
Score = 52.0 bits (123), Expect = 2e-06
Identities = 73/285 (25%), Positives = 103/285 (36%), Gaps = 63/285 (22%)
Query: 295 PGSQSPVVPAG-----AVSTGSSSPGTPQPAPQLPLNAAP-PSSVPPVPPSEALPPPACP 348
PG PA + S GTP PAP LP A P P PP+PP+ A P P
Sbjct: 363 PGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPA-APPLPCAQ 421
Query: 349 SAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEG-------PATVQSVED----FVPDD 397
A P +SPA + P PP P A P+ ++ + + ++
Sbjct: 422 KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGS 481
Query: 398 RLDRSFLE-----DTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPR 452
R + FL P E K G + ++ E L P +D P
Sbjct: 482 RREDRFLSHRPGPTVAPQSKEGKKGPRLPEK------ETLLSLP----------AKDTPP 525
Query: 453 GSPPLPAGPVPSQDITLSSEEEAEVA----------APTKGPAPAPQQC-SEPETKWSSI 501
G VP + + SS E E A P P P+ +Q +E E + SS
Sbjct: 526 G--------VPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSA 577
Query: 502 --PASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEP 544
+KP G+ P + P GG G + ++P A+ P
Sbjct: 578 AEKEAKPSIGSLPPK---PRLEGGRICENGADDDKLSKPVAKNLP 619
Score = 51.6 bits (122), Expect = 3e-06
Identities = 94/409 (22%), Positives = 127/409 (31%), Gaps = 80/409 (19%)
Query: 314 PGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPP 373
P P P P ++ P S P PPS A PPP P P S+ APP
Sbjct: 143 PPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSM-------------APP 189
Query: 374 PPEPVPAAEGPATVQSVEDFVPDDRLDRSF-LEDTTPARDEKKVGAKAAQQDSDSDGEAL 432
PP + A P T+ S P D + + L P A A + G L
Sbjct: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRL 249
Query: 433 GGNPMVAGFQDDVDLE----DQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPT--KGPAP 486
V ++ DV L + R SPP P + L E + P K P P
Sbjct: 250 FPPGGVTKWKSDVALNGRQAEATRASPP--RSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307
Query: 487 APQQCSEPETKWSSIPASKPRRGT--APTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEP 544
P + S + + K T AP+R PP RP +++ P
Sbjct: 308 TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP-------------SFHIRPASQVYP 354
Query: 545 GKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEG 604
+ PE ++ + P S RA
Sbjct: 355 DRA---------PEPDCPGELKATAPASPRLGQSQSQADERA------------------ 387
Query: 605 PAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEE 664
PPP P LP PA L + L A P P +K G +
Sbjct: 388 -GTPPPAPPLPPPAPPLPPPAP----PLPPAAP----------PLPCAQKAAHPPAGFTK 432
Query: 665 EEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEAFLGG 713
K++ K K + E R P E+ +EL A+L G
Sbjct: 433 TPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEK-LRNELAAYLCG 480
Score = 46.2 bits (108), Expect = 1e-04
Identities = 72/304 (23%), Positives = 95/304 (31%), Gaps = 57/304 (18%)
Query: 333 VPPVPPSEALPPP----------ACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAE 382
+PP PP A PP PS P+ L P APPPP + A
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
Query: 383 GPATVQSVEDFVPDDRLDRS-FLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGF 441
P T+ S P D + + L P A A + G L V +
Sbjct: 199 PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258
Query: 442 QDDVDLE----DQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPT--KGPAPAPQQCSEPE 495
+ DV L + R SP P P + L E + P K P P P + S
Sbjct: 259 KSDVALNGRQAEATRASP--PRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 496 TKWSSIPASKPRRGT--APTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSS 553
+ + K T AP+R PP RP +++ P +
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPP-------------SFHIRPASQVYPDRA------ 357
Query: 554 ESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPK 613
PE ++ + P S RA P PA P PPP
Sbjct: 358 ---PEPDCPGELKATAPASPRLGQSQSQADERAGTPP--------------PAPPLPPPA 400
Query: 614 LPLP 617
PLP
Sbjct: 401 PPLP 404
Score = 38.1 bits (87), Expect = 0.029
Identities = 76/303 (25%), Positives = 102/303 (33%), Gaps = 74/303 (24%)
Query: 292 SPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351
SPS + +P + P P PAP APP+ P L P P
Sbjct: 205 SPSIPTPPDFIPPAPPLAFLAPPPPPVPAP------APPAPASPHTVGTRLFP---PGGV 255
Query: 352 APRRSIISRLFGTSPATEAAPP--PPEPVPAAEGPATVQSVEDFVPDDRLDRSF-LEDTT 408
+S ++ + AT A+PP P EP +A GP + P RSF + T
Sbjct: 256 TKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP-------NPEPHLTFPRSFKVPPPT 308
Query: 409 PAR------------DEKKVGA----------------KAAQQ-------DSDSDGEALG 433
P R K+ GA + A Q + D GE
Sbjct: 309 PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA 368
Query: 434 GNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSE 493
P D+ G+PP PA P+P L A P P P Q+ +
Sbjct: 369 TAPASPRLGQSQSQADERAGTPP-PAPPLPPPAPPL--PPPAPPLPPAAPPLPCAQKAAH 425
Query: 494 P-----ETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGE 548
P +T SS PA KP+ PP P T R P++ME + E
Sbjct: 426 PPAGFTKTPKSSSPALKPKPN--------PPSP----ENTASSAPVDWRDPSQMEKLRNE 473
Query: 549 QAS 551
A+
Sbjct: 474 LAA 476
Score = 35.8 bits (81), Expect = 0.14
Identities = 69/302 (22%), Positives = 97/302 (32%), Gaps = 45/302 (14%)
Query: 290 GQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349
GQ P SQ P+ A GS P A +LP A S+ P S C
Sbjct: 715 GQPEKPASQEVSTPSQARGEGS-----PSEATRLPTQGARSSAAFPPKTSPGGGEVPCLY 769
Query: 350 APAPRRSIISRLFGTSPATEA---APPPPEPVPAAEGPA-TVQSVEDFVPDDRLDRSFLE 405
P +S +SR T A A P EPV E P + P D L R +
Sbjct: 770 KPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT 829
Query: 406 DTTPARDEKK---VGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPV 462
R + A+ Q S G ALG + + +D + S G
Sbjct: 830 GEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTP 889
Query: 463 PSQDITLSSEEEAEVAAPTKGPAP-----------------APQQCSEPETK----WSSI 501
S + +EAE +P P ++PE + W +
Sbjct: 890 NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERV 949
Query: 502 -PASKPRRGTAPTRTAAPPWPGGVS-----------VRTGPEKRSSTRPPAEMEPGKGEQ 549
P++ P+ P ++PP P + PE + PPA G Q
Sbjct: 950 APSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQ 1009
Query: 550 AS 551
+S
Sbjct: 1010 SS 1011
Score = 33.1 bits (74), Expect = 0.94
Identities = 53/222 (23%), Positives = 80/222 (36%), Gaps = 34/222 (15%)
Query: 321 PQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPA 380
P +P A P ++PP +A PA P P+ ++ G + +A P P+ A
Sbjct: 639 PAIPPKATPEPAIPP----KATLWPATP----PKATL-----GPATPLKATSGPTTPLKA 685
Query: 381 AEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVA- 439
GPA + S +P +D+ PA +K ++ S + GE G+P A
Sbjct: 686 TSGPA-IASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGE---GSPSEAT 741
Query: 440 -----GFQDDVDLEDQPRGSPPLPAGPVP------SQDITLSSEEEAEVAAPTKGPAPAP 488
G + P+ SP G VP +LS E + +G A P
Sbjct: 742 RLPTQGARSSAAF--PPKTSP--GGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGP 797
Query: 489 QQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGP 530
+ E + +PA P P G V R P
Sbjct: 798 GEPVEVKEP-PGLPAKPPASAQPTDELLRHPVTGEVVERGSP 838
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 68.6 bits (166), Expect = 2e-11
Identities = 77/268 (28%), Positives = 104/268 (38%), Gaps = 32/268 (11%)
Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPS--EALPPP---AC 347
P+PG + S S P T P P L L PP S+ P PP EAL PP +
Sbjct: 146 PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSS 205
Query: 348 PSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSV-EDFVPDDRLDRSFLED 406
PS P P I A A PPPP P PA PA+ +V P + + +
Sbjct: 206 PSIPTPPDFIPP---APPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDV 262
Query: 407 TTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQD 466
R + A + ++ G ALG NP + + PR P PV +
Sbjct: 263 ALNGRQAEATRASPPRSPAEPKGSALGPNP-----EPHLTF---PRSFKVPPPTPVRTSS 314
Query: 467 ITLSSEEEA---EVAAPTKGPAPAPQQCSEPETKWSSIPASK--PRRGTAP-----TRTA 516
I + +EA E A K P+ P S + PAS+ P R P +
Sbjct: 315 IPVQEAQEAPRKEEGATKKAPSRLPLPPS-----FHIRPASQVYPDRAPEPDCPGELKAT 369
Query: 517 APPWPGGVSVRTGPEKRSSTRPPAEMEP 544
AP P ++ ++R+ T PPA P
Sbjct: 370 APASPRLGQSQSQADERAGTPPPAPPLP 397
Score = 52.0 bits (123), Expect = 2e-06
Identities = 73/285 (25%), Positives = 103/285 (36%), Gaps = 63/285 (22%)
Query: 295 PGSQSPVVPAG-----AVSTGSSSPGTPQPAPQLPLNAAP-PSSVPPVPPSEALPPPACP 348
PG PA + S GTP PAP LP A P P PP+PP+ A P P
Sbjct: 363 PGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPA-APPLPCAQ 421
Query: 349 SAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEG-------PATVQSVED----FVPDD 397
A P +SPA + P PP P A P+ ++ + + ++
Sbjct: 422 KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGS 481
Query: 398 RLDRSFLE-----DTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPR 452
R + FL P E K G + ++ E L P +D P
Sbjct: 482 RREDRFLSHRPGPTVAPQSKEGKKGPRLPEK------ETLLSLP----------AKDTPP 525
Query: 453 GSPPLPAGPVPSQDITLSSEEEAEVA----------APTKGPAPAPQQC-SEPETKWSSI 501
G VP + + SS E E A P P P+ +Q +E E + SS
Sbjct: 526 G--------VPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSA 577
Query: 502 --PASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEP 544
+KP G+ P + P GG G + ++P A+ P
Sbjct: 578 AEKEAKPSIGSLPPK---PRLEGGRICENGADDDKLSKPVAKNLP 619
Score = 51.6 bits (122), Expect = 3e-06
Identities = 94/409 (22%), Positives = 127/409 (31%), Gaps = 80/409 (19%)
Query: 314 PGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPP 373
P P P P ++ P S P PPS A PPP P P S+ APP
Sbjct: 143 PPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSM-------------APP 189
Query: 374 PPEPVPAAEGPATVQSVEDFVPDDRLDRSF-LEDTTPARDEKKVGAKAAQQDSDSDGEAL 432
PP + A P T+ S P D + + L P A A + G L
Sbjct: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRL 249
Query: 433 GGNPMVAGFQDDVDLE----DQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPT--KGPAP 486
V ++ DV L + R SPP P + L E + P K P P
Sbjct: 250 FPPGGVTKWKSDVALNGRQAEATRASPP--RSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307
Query: 487 APQQCSEPETKWSSIPASKPRRGT--APTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEP 544
P + S + + K T AP+R PP RP +++ P
Sbjct: 308 TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP-------------SFHIRPASQVYP 354
Query: 545 GKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEG 604
+ PE ++ + P S RA
Sbjct: 355 DRA---------PEPDCPGELKATAPASPRLGQSQSQADERA------------------ 387
Query: 605 PAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEE 664
PPP P LP PA L + L A P P +K G +
Sbjct: 388 -GTPPPAPPLPPPAPPLPPPAP----PLPPAAP----------PLPCAQKAAHPPAGFTK 432
Query: 665 EEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEAFLGG 713
K++ K K + E R P E+ +EL A+L G
Sbjct: 433 TPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEK-LRNELAAYLCG 480
Score = 46.2 bits (108), Expect = 1e-04
Identities = 72/304 (23%), Positives = 95/304 (31%), Gaps = 57/304 (18%)
Query: 333 VPPVPPSEALPPP----------ACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAE 382
+PP PP A PP PS P+ L P APPPP + A
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
Query: 383 GPATVQSVEDFVPDDRLDRS-FLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGF 441
P T+ S P D + + L P A A + G L V +
Sbjct: 199 PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258
Query: 442 QDDVDLE----DQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPT--KGPAPAPQQCSEPE 495
+ DV L + R SP P P + L E + P K P P P + S
Sbjct: 259 KSDVALNGRQAEATRASP--PRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 496 TKWSSIPASKPRRGT--APTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSS 553
+ + K T AP+R PP RP +++ P +
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPP-------------SFHIRPASQVYPDRA------ 357
Query: 554 ESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPK 613
PE ++ + P S RA P PA P PPP
Sbjct: 358 ---PEPDCPGELKATAPASPRLGQSQSQADERAGTPP--------------PAPPLPPPA 400
Query: 614 LPLP 617
PLP
Sbjct: 401 PPLP 404
Score = 38.1 bits (87), Expect = 0.029
Identities = 76/303 (25%), Positives = 102/303 (33%), Gaps = 74/303 (24%)
Query: 292 SPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351
SPS + +P + P P PAP APP+ P L P P
Sbjct: 205 SPSIPTPPDFIPPAPPLAFLAPPPPPVPAP------APPAPASPHTVGTRLFP---PGGV 255
Query: 352 APRRSIISRLFGTSPATEAAPP--PPEPVPAAEGPATVQSVEDFVPDDRLDRSF-LEDTT 408
+S ++ + AT A+PP P EP +A GP + P RSF + T
Sbjct: 256 TKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP-------NPEPHLTFPRSFKVPPPT 308
Query: 409 PAR------------DEKKVGA----------------KAAQQ-------DSDSDGEALG 433
P R K+ GA + A Q + D GE
Sbjct: 309 PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA 368
Query: 434 GNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSE 493
P D+ G+PP PA P+P L A P P P Q+ +
Sbjct: 369 TAPASPRLGQSQSQADERAGTPP-PAPPLPPPAPPL--PPPAPPLPPAAPPLPCAQKAAH 425
Query: 494 P-----ETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGE 548
P +T SS PA KP+ PP P T R P++ME + E
Sbjct: 426 PPAGFTKTPKSSSPALKPKPN--------PPSP----ENTASSAPVDWRDPSQMEKLRNE 473
Query: 549 QAS 551
A+
Sbjct: 474 LAA 476
Score = 35.8 bits (81), Expect = 0.14
Identities = 69/302 (22%), Positives = 97/302 (32%), Gaps = 45/302 (14%)
Query: 290 GQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349
GQ P SQ P+ A GS P A +LP A S+ P S C
Sbjct: 715 GQPEKPASQEVSTPSQARGEGS-----PSEATRLPTQGARSSAAFPPKTSPGGGEVPCLY 769
Query: 350 APAPRRSIISRLFGTSPATEA---APPPPEPVPAAEGPA-TVQSVEDFVPDDRLDRSFLE 405
P +S +SR T A A P EPV E P + P D L R +
Sbjct: 770 KPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT 829
Query: 406 DTTPARDEKK---VGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPV 462
R + A+ Q S G ALG + + +D + S G
Sbjct: 830 GEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTP 889
Query: 463 PSQDITLSSEEEAEVAAPTKGPAP-----------------APQQCSEPETK----WSSI 501
S + +EAE +P P ++PE + W +
Sbjct: 890 NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERV 949
Query: 502 -PASKPRRGTAPTRTAAPPWPGGVS-----------VRTGPEKRSSTRPPAEMEPGKGEQ 549
P++ P+ P ++PP P + PE + PPA G Q
Sbjct: 950 APSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQ 1009
Query: 550 AS 551
+S
Sbjct: 1010 SS 1011
Score = 33.1 bits (74), Expect = 0.94
Identities = 53/222 (23%), Positives = 80/222 (36%), Gaps = 34/222 (15%)
Query: 321 PQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPA 380
P +P A P ++PP +A PA P P+ ++ G + +A P P+ A
Sbjct: 639 PAIPPKATPEPAIPP----KATLWPATP----PKATL-----GPATPLKATSGPTTPLKA 685
Query: 381 AEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVA- 439
GPA + S +P +D+ PA +K ++ S + GE G+P A
Sbjct: 686 TSGPA-IASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGE---GSPSEAT 741
Query: 440 -----GFQDDVDLEDQPRGSPPLPAGPVP------SQDITLSSEEEAEVAAPTKGPAPAP 488
G + P+ SP G VP +LS E + +G A P
Sbjct: 742 RLPTQGARSSAAF--PPKTSP--GGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGP 797
Query: 489 QQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGP 530
+ E + +PA P P G V R P
Sbjct: 798 GEPVEVKEP-PGLPAKPPASAQPTDELLRHPVTGEVVERGSP 838
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 67.4 bits (163), Expect = 4e-11
Identities = 110/449 (24%), Positives = 155/449 (34%), Gaps = 84/449 (18%)
Query: 281 GHASPLAANGQSPSPGSQSPVVPAGAV-----STGSSSPGTPQP---APQLPLNAAPPSS 332
GHA PL + S G+ + P +V S G S P QP A Q PL A
Sbjct: 1012 GHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVG 1071
Query: 333 VPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVED 392
V PVP + PPAC AP +I+ + SPA ++ P +P A P+ V +V
Sbjct: 1072 VSPVPSPQL--PPAC---AAPGGPVITAFYSGSPAPTSSAPLAQPSQAP--PSLVYTVA- 1123
Query: 393 FVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPR 452
T PA G A + + P L P+
Sbjct: 1124 -----------TSTTPPAATILPKGPPAPATATPAPTSPF---PSATAGSMTYSLV-APK 1168
Query: 453 GSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEP-----------ETKWSSI 501
P P P + S + A + P PAP+Q EP E +
Sbjct: 1169 AQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPT 1228
Query: 502 PASKP--RRGTAPTRTAAPPWPGGVSVRT---GPEKRSSTRPPAEME---PGKGEQASSS 553
P + P PT ++PP P RT GPE +S P + + PG+G +
Sbjct: 1229 PPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGE 1288
Query: 554 ESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDV--------------- 598
P P A ++ P SE S + R A D P R + +
Sbjct: 1289 PPTPPSPAPAPAVA-----PGGSSE-SSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTF 1342
Query: 599 ----------TDEDEGPAEPP---PPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGK 645
D +E AE P P LP P + S LG K S++
Sbjct: 1343 DSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDS 1402
Query: 646 EGKTPSKEKKKKKKKGKEEEEKAAKKKSK 674
+ P+ K+K +++ E K +K
Sbjct: 1403 APEDPTSPKRKMRRRSSCSSEPNTPKSAK 1431
Score = 43.1 bits (100), Expect = 0.001
Identities = 93/385 (24%), Positives = 127/385 (32%), Gaps = 78/385 (20%)
Query: 293 PSPGSQSPVVPAGAVSTG----SSSPGTPQPAPQL--PLNAAPPSSVPPVPPSEALPPPA 346
P + V+ A A + G S P P P Q P+ A PP + P + L P A
Sbjct: 868 PGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLA 927
Query: 347 CPS---------APAPRRSIISRLFGTSPATEAAPP------PPEPVPAAEG------PA 385
PS P P ++S F A PP P PV G PA
Sbjct: 928 APSMSVRGGGAGQPLP---LVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPA 984
Query: 386 TVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDV 445
T+ P + + L +T + G A + S + G G V
Sbjct: 985 TLPG-----PTSQPQKVLLPSSTRITYVQSAGGHALPLGT-SPASSQAGTVTSYGPTSSV 1038
Query: 446 DLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTK---GPAPAPQ---QCSEP----- 494
L G P+GP Q L S +A + AP + P P+PQ C+ P
Sbjct: 1039 ALGFTSLG----PSGPAFVQ--PLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVI 1092
Query: 495 ETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRS---------STRPPAEMEPG 545
+S PA A A P V+ T P + +T PA P
Sbjct: 1093 TAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPF 1152
Query: 546 KGEQASS----------SESDPEGPIAAQMLSFVMDDPDFES-----EGSDTQRRADDFP 590
A S P+ P + + FE+ G ++ + P
Sbjct: 1153 PSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGP 1212
Query: 591 VRDDPSDVTDEDEGPAEPPPPPKLP 615
VR +P+ E EG PP PP LP
Sbjct: 1213 VR-EPTAPESELEGQPTPPAPPPLP 1236
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 20/102 (19%)
Query: 287 AANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPA----PQLPLN-AAPPSSVPPVPPSEA 341
AA PG+++P+ T ++ TP PA P P + + + PP+PP
Sbjct: 1521 AATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPP--- 1577
Query: 342 LPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEG 383
PP + P P G A + +PPPP P AA G
Sbjct: 1578 -PPESGPGQP-----------GWEGAPQPSPPPPGPSTAATG 1607
Score = 38.1 bits (87), Expect = 0.029
Identities = 58/254 (22%), Positives = 85/254 (33%), Gaps = 30/254 (11%)
Query: 324 PLNAAPPSSVPPVPP-----SEALPPPACPSAPAPRRSIISRLF----GTSPATEA---- 370
PL+ PP PP PP P + S+PA + + F GT A E+
Sbjct: 509 PLDPEPPG--PPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGS 566
Query: 371 -APPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDG 429
A P P P A GPAT F+P D T + + VG S
Sbjct: 567 TAGPLRPPPPGAGGPATPSKATRFLPMD-------PATFRRKRPESVGGLEPPGPSVIAA 619
Query: 430 EALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQ 489
GG ++ + E+Q G +P+ P PS AAP PA
Sbjct: 620 PPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSL-------AYGAPAAPLSRPAATMV 672
Query: 490 QCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQ 549
+ +P + T+ A+P G G R P + ++
Sbjct: 673 TNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDK 732
Query: 550 ASSSESDPEGPIAA 563
S++ + P + A
Sbjct: 733 KSAAATSPAPHLVA 746
Score = 37.4 bits (85), Expect = 0.050
Identities = 29/75 (38%), Positives = 32/75 (42%), Gaps = 12/75 (16%)
Query: 287 AANGQSPSP-GSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPP 345
AA +PSP G P P SS GT Q AP LP PP S P P E P P
Sbjct: 1545 AAPAPTPSPAGGPDPTSP-------SSDSGTAQAAPPLP---PPPESGPGQPGWEGAPQP 1594
Query: 346 ACPSAPAPRRSIISR 360
+ P P P + R
Sbjct: 1595 S-PPPPGPSTAATGR 1608
Score = 34.3 bits (77), Expect = 0.42
Identities = 38/157 (24%), Positives = 55/157 (35%), Gaps = 11/157 (7%)
Query: 258 SVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP 317
SVQ Q + +++ ++ +A GS P P GA S PG P
Sbjct: 52 SVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPP 111
Query: 318 QPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEP 377
P + P PP EA PP P + S F + + E P P
Sbjct: 112 HPLGVVESGKGP----PPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLP-- 165
Query: 378 VPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEK 414
G QS+ +P +R S + +P + EK
Sbjct: 166 ----PGKRRTQSL-SALPKERDSSSEKDGRSPNKREK 197
Score = 34.3 bits (77), Expect = 0.42
Identities = 36/111 (32%), Positives = 45/111 (40%), Gaps = 11/111 (9%)
Query: 530 PEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDF 589
PE PP G G SSS S P A+ SF + F+++ S A
Sbjct: 512 PEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAG-- 569
Query: 590 PVRDDPSDVTDEDEGPAEPPPPPK-LPL-PA-FRLKNDSDLFGLGLEEAGP 637
P+R P GPA P + LP+ PA FR K + GLE GP
Sbjct: 570 PLRPPPPGA----GGPATPSKATRFLPMDPATFRRKRPESVG--GLEPPGP 614
Score = 31.2 bits (69), Expect = 3.6
Identities = 76/305 (24%), Positives = 113/305 (37%), Gaps = 64/305 (20%)
Query: 296 GSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP-PSEALP----PPACPSA 350
G++ P PA +++ G+ + +PA + N P S PVP S+ P A P+
Sbjct: 644 GARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPND 703
Query: 351 PAPRRSII---SRLFGTSP-----------ATEAAPPPPEPV------PAAEGPATVQSV 390
A R+ + SR+ G SP + A P P V + PATV ++
Sbjct: 704 TAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNL 763
Query: 391 EDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQ 450
P PA + A+ A + G G +G V L
Sbjct: 764 LVGTPG---------YGAPAPPAVQFIAQGAPGGGTTAGSGAGAG---SGPNGPVPLGIL 811
Query: 451 PRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGT 510
G+ G Q I + ++ +VA PAPAP P TK A+ P G
Sbjct: 812 QPGALGKAGGITQVQYILPTLPQQLQVA-----PAPAP----APGTK-----AAAP-SGP 856
Query: 511 APTRTAAPPWPGGVSVRTGPEKRSSTRPP---------AEMEPGKGEQASSSESDPEGPI 561
APT + P G S T + ++T P P K + S ++ P G
Sbjct: 857 APTTSIRFTLPPGTS--TNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGG- 913
Query: 562 AAQML 566
+AQ+L
Sbjct: 914 SAQLL 918
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 66.6 bits (161), Expect = 8e-11
Identities = 93/412 (22%), Positives = 159/412 (38%), Gaps = 56/412 (13%)
Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPS---SVPPVPPSEALPPPACPS 349
P P ++P+V A S+ +P + +L PPS S PP+E LPPPA S
Sbjct: 318 PPPAEEAPLVEFPAEIQPPSAEESP--SVELLAEILPPSAEESPSEEPPAEILPPPAEKS 375
Query: 350 APAPRRSIISRLFGTSPATEAAPPPPEPVPAA----EGPATVQ--SVEDFVPDDRLDRSF 403
P ++ + SP+ + AP +P+PA E PA V+ +VE+ + D +
Sbjct: 376 ---PSVELLGEI--RSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQ---PL 427
Query: 404 LEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPM---VAGFQDDVDLEDQPRGSPPLPAG 460
L + P + +++ A + + +P+ + +++ PP
Sbjct: 428 LPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADET 487
Query: 461 PV----PSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWS-SIPASK-PRRGTAPTR 514
P P + T + E AEV +P A + +E + + PA + P +P
Sbjct: 488 PAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLS 547
Query: 515 TAAPPWPGGVSVRTGPEKRSSTRP-PAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDP 573
V++ K S P E++P GE+ ++ E+ A Q+L+
Sbjct: 548 EETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASA----AIQLLAAT---- 599
Query: 574 DFESEGSDTQRRADDFPVRDDPSDVTDE--DEGPAEPPPPPKLPLPAFRLKNDSDLFGLG 631
E+ + P + P++V +E PAE PPP PA
Sbjct: 600 --EASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA------------- 644
Query: 632 LEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEE 683
E P + E E + P E+ + + EE A+ +S + EE
Sbjct: 645 --EVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEE 694
Score = 43.9 bits (102), Expect = 5e-04
Identities = 47/187 (25%), Positives = 70/187 (37%), Gaps = 24/187 (12%)
Query: 317 PQPAPQLPLNAAPPSSVPPVPPSEALPPPA--CPSAPAPRRSIISRLFGTSPATEAAPPP 374
P PA + P PP + P+E PPPA P+ P + + P E AP
Sbjct: 612 PPPAEEAPAEVQPPPAEEA--PAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 669
Query: 375 PEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGG 434
+P PA E PA VQS+ + ++ + +P D+ V A+ A D S
Sbjct: 670 VQPPPAEEAPAEVQSLP--AEETPIEETLAAVHSPPADD--VPAEEASVDKHSPP----- 720
Query: 435 NPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEP 494
D + E+ P G P PS+ + E+ + +PQ P
Sbjct: 721 -------ADLLLTEEFPIGEASAEVSPPPSE----QTPEDEALVENVSTEFQSPQVAGIP 769
Query: 495 ETKWSSI 501
K S+
Sbjct: 770 AVKLGSV 776
Score = 37.0 bits (84), Expect = 0.065
Identities = 89/432 (20%), Positives = 150/432 (34%), Gaps = 68/432 (15%)
Query: 300 PVVPAG-AVSTGSSSPGTPQPAPQLPLNAAPP------SSVPPVPPSEALPPPACPSAPA 352
PVV G AV +S+ P + P PP + P P E +
Sbjct: 241 PVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEET 300
Query: 353 PRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQ--SVEDFVPDDRLDRSFLEDTTPA 410
P + + S + PPP E P E PA +Q S E+ P L L +
Sbjct: 301 PDAEAATAVAENS--VKVQPPPAEEAPLVEFPAEIQPPSAEE-SPSVELLAEILPPSAEE 357
Query: 411 RDEKKVGAKAAQQDSDSDG--EALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDIT 468
++ A+ ++ E LG ++ P+ P+P++
Sbjct: 358 SPSEEPPAEILPPPAEKSPSVELLG------------EIRSPSAQKAPIEVQPLPAEGAL 405
Query: 469 LSSEEEAEVAAPTKGPAPA------PQQCSEPETKWSSI-PASKPRRGTAPTRTAAPPWP 521
E A+V PT A P++ E + + A + APT +P
Sbjct: 406 --EEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPK 463
Query: 522 GGVSVRTGPEKR--SSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEG 579
+ E + ++T PPA+ P + S E+ E A++ S + ++ E
Sbjct: 464 ETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAE-EAHAEVQSPLAEETTAEEAS 522
Query: 580 SDTQ------RRADDFP--VRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLG 631
++ Q AD+ P + S+ T +E PAE P G+
Sbjct: 523 AEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSP--------------SAKGVS 568
Query: 632 LEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRR 691
+EEA E + PS E+ ++ + AA + S + + + E
Sbjct: 569 IEEA--------PLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPA 620
Query: 692 QQRPPRSRERTA 703
+ +PP + E A
Sbjct: 621 EVQPPPAEEAPA 632
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 66.2 bits (160), Expect = 1e-10
Identities = 90/370 (24%), Positives = 129/370 (34%), Gaps = 45/370 (12%)
Query: 280 RGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLP-LNAA--PPSSVPP- 335
+G ++P AA SP + +P GA +T +++ +P+ P P L A PP++ PP
Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 336 ------VPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPE----PVPAAEGPA 385
P + P P + P+P+ + + +P T AA PP P +G
Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149
Query: 386 TVQSVEDFVPDDRLDRSFLE--DTTP-ARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQ 442
T + P L + TTP A G A + P G
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1209
Query: 443 DDVDLEDQPRGSPPLPAGPVPSQDITLSSEE--------EAEVAAPTKGP-------APA 487
P+G+P PA PS L++ A +P GP AP
Sbjct: 1210 ----ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265
Query: 488 PQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKG 547
P + P K A+ P +G PP P G T P K + T P A KG
Sbjct: 1266 PPAATPPSLKGGL--ATPPHKGAPNPAVVTPPSPKG-GPATSPPKGAPTPPAATPPSPKG 1322
Query: 548 EQASSSESDPEGPIAAQMLS----FVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDE 603
+ P A S + S+G T + + P P+
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT--PPAATPSHKG 1380
Query: 604 GPAEPPPPPK 613
GPA PP PK
Sbjct: 1381 GPAMTPPSPK 1390
Score = 62.8 bits (151), Expect = 1e-09
Identities = 95/353 (26%), Positives = 124/353 (35%), Gaps = 56/353 (15%)
Query: 284 SPLAANGQSPSPGSQSPVVP-AGAVSTGSSSPGTPQ--PAPQLPLNAAPPSSVPPVPPSE 340
+P N P G +P A A+S SSSP + PAP+ + A+P P PP+
Sbjct: 887 TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK-GIPASPSPKGAPTPPAA 945
Query: 341 ALPPP-ACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRL 399
P P P+ P+P+ + T PA A PP P+ PA P + P
Sbjct: 946 TPPSPKGGPATPSPKWA------PTPPA--ATPPSPKGGPATPSPKGAPTPPAATP---- 993
Query: 400 DRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVD-----LEDQPRGS 454
+P K A + G+P F P+GS
Sbjct: 994 -------PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046
Query: 455 P---PLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTA 511
P PLP G + TL S + KG AP P + P K PA+ +G
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKG-APTPPAATPPSPKGG--PATPSPKGAP 1103
Query: 512 PTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQAS-SSESDPEGPIAAQMLSFVM 570
A PP P G + T P K + T P A KG A+ + P P A
Sbjct: 1104 MPPAATPPSPKG-GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT------- 1155
Query: 571 DDPDFESEGSDT--QRRADDFPVRDDPSD----VTDEDEG----PAEPPPPPK 613
P G T + A P PS T +G PA PP PK
Sbjct: 1156 --PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206
Score = 62.8 bits (151), Expect = 1e-09
Identities = 81/325 (24%), Positives = 113/325 (34%), Gaps = 52/325 (16%)
Query: 280 RGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPS 339
+G +P AA SP G +P P GA +++P +P+ P + P++ PPS
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPS-PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135
Query: 340 E----ALPPP----ACPSA--PAPRRSIISRLFGTSPATEAAPPPPEP----VPAAEGPA 385
A PPP P+A P+P+ + + +P T AA PP P+ +G
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 386 TVQSVEDFVPDDRLDRSFLED--TTPARDEKKV-GAKAAQQDSDSDGEALGGNPMVAGFQ 442
T + P L + TTPA G A + P G
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255
Query: 443 DDVDLEDQPRGSPPLPAGPVPSQD----------------ITLSSEEEAEVAAPTKGPAP 486
P+G+P PA PS +T S + +P KG AP
Sbjct: 1256 ----ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG-AP 1310
Query: 487 APQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVR-----------TGPEKRSS 535
P + P K S P + P +G PP P G T P +
Sbjct: 1311 TPPAATPPSPKGS--PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368
Query: 536 TRPPAEMEPGKGEQASSSESDPEGP 560
PPA KG A + S GP
Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGP 1393
Score = 62.0 bits (149), Expect = 2e-09
Identities = 88/352 (25%), Positives = 119/352 (33%), Gaps = 47/352 (13%)
Query: 277 ARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPV 336
A S +SP A G + P GA + +++P +P+ P P P+
Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 337 PPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPD 396
PPS P P+ P+P+ G A PP P+ PA P + P
Sbjct: 970 PPS----PKGGPATPSPK--------GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017
Query: 397 DRLDRSFLEDTTPARDEKKVGAK---AAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRG 453
+PA GA AA S A P A L P+G
Sbjct: 1018 S-------PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL-PSPKG 1069
Query: 454 SPPLPA-GPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAP 512
P P+ P+ + A P+ AP P + P K A+ P +G
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL--ATPPHKGAPT 1127
Query: 513 TRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQAS-SSESDPEGPIAAQMLSFVMD 571
T A PP P G + T P K + T P A KG A+ + P P A
Sbjct: 1128 TPAATPPSPKG-GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT-------- 1178
Query: 572 DPDFESEG--SDTQRRADDFPVRDDPSD----VTDEDEG----PAEPPPPPK 613
P G + + + A P PS T +G PA PP PK
Sbjct: 1179 -PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Score = 61.2 bits (147), Expect = 3e-09
Identities = 85/339 (25%), Positives = 114/339 (33%), Gaps = 86/339 (25%)
Query: 277 ARSRGHASPLAANGQSPSP--GSQSPVVPAGAVSTGSSSPGTP----------------- 317
A S+G + LA SPSP S SP GS+ P TP
Sbjct: 781 ASSKGTLTYLA---DSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLP 837
Query: 318 -----------------QPAPQLPLNAAPPSSVPP-------VPPSEA-------LP-PP 345
P P P A PS+V P +PP E LP P
Sbjct: 838 ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK 897
Query: 346 ACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLE 405
P+ PAP+++ + +SP A P P+ +PA+ P + P
Sbjct: 898 EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP---------- 947
Query: 406 DTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQ 465
+P K A + + G P P+G+P PA PS
Sbjct: 948 -PSPKGGPATPSPKWAPTPPAATPPSPKGGPAT----------PSPKGAPTPPAATPPS- 995
Query: 466 DITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKP-RRGTAPTRTAAPPWPGGV 524
+ A P+ AP P + P K S PA+ P +G + A PP P G
Sbjct: 996 -------PKGGPATPSPKGAPTPPAVTPPSPKGS--PAATPFPKGASTPPAATPPSPKGS 1046
Query: 525 SVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAA 563
T K + T P A + KG A+ S P AA
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085
Score = 54.7 bits (130), Expect = 3e-07
Identities = 90/376 (23%), Positives = 133/376 (35%), Gaps = 60/376 (15%)
Query: 280 RGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPL-NAAP--PSSVPPV 336
+G + AA SP G +P P GA +T +++P +P+ P AP P++ PP
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPP-PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181
Query: 337 PPSEALPP-----PACPSA--PAPRRSIISRLFGTSPATEAAPPP--------PEPVPAA 381
P P P P+A P+P+ + + +P T AA PP P P A
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241
Query: 382 EGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKV-GAKAAQQDSDSDGEALGGNPMVAG 440
PA P + T PA + G A + A+ P G
Sbjct: 1242 TTPAATPPSPKGGPATPPPKG--APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299
Query: 441 FQDDVDLEDQPRGSPPLPA--GPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKW 498
P+G+P PA P P + + P KG AP P + P K
Sbjct: 1300 GP----ATSPPKGAPTPPAATPPSP---------KGSPGTPPPKG-APTPPAVTPPSPKG 1345
Query: 499 S-SIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDP 557
+ ++PA+ P PT ++ P + + + PP+ P +G S + DP
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS---PKRGPAIPSPKGDP 1402
Query: 558 EGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDP-----SDVTDEDEG-------- 604
P + EG+ T + D P P + T +G
Sbjct: 1403 TSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK 1462
Query: 605 -----PAEPPPPPKLP 615
PA PP PK P
Sbjct: 1463 GDPTLPAVTPPSPKEP 1478
Score = 53.9 bits (128), Expect = 5e-07
Identities = 88/416 (21%), Positives = 139/416 (33%), Gaps = 48/416 (11%)
Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342
A+ ++ G +P S+ P A + P P+P+ P P P L
Sbjct: 1351 ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL 1410
Query: 343 PPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPAT-VQSVEDFVPDDRLDR 401
P P+ P R T + PP PV + PAT P + D
Sbjct: 1411 SPKKAPATPVTREGA-----ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP 1465
Query: 402 SFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAG- 460
+ T P+ E + A S A PM A V + P+ P P+
Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA-PMGAPTLPAV-IPSSPKEVPATPSSR 1523
Query: 461 --PVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAP 518
P+ + TL S++ AP + P P+ K +IP K T ++ A+
Sbjct: 1524 RDPI-APTATLLSKKTPATLAPKEALIPPAMTVPSPK-KTPAIPTPKEAPATPSSKEASS 1581
Query: 519 P-------WPGGVSVR--------TGPEKRSSTRPPAEMEPG--KGEQASSSESDPEGPI 561
P + G S + T P + + PPA P KG + + P P
Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP 1641
Query: 562 AAQMLSFVMDDPDFESE-----GSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPL 616
S + D P + G+ + + P + P+ + + PA P P +
Sbjct: 1642 VTP--SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA-PESTPIITA 1698
Query: 617 PAFRLKNDSDLFGLGLEEAGPKESSEEGKEGK---------TPSKEKKKKKKKGKE 663
P R + P S++ G +G P ++ K KGK+
Sbjct: 1699 PT-RKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753
Score = 35.8 bits (81), Expect = 0.14
Identities = 42/156 (26%), Positives = 60/156 (38%), Gaps = 25/156 (16%)
Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPA 352
P P S S + A S S P P P P LP P P P L P+ P APA
Sbjct: 1783 PKPESASV---SAAPSPPVSLPLAPSPVPTLP----PKQQFLPSSPGLVLESPSKPLAPA 1835
Query: 353 PRRSIISRLFGTSPATEAAP--------PPPE------PVPAAEGPATVQ---SVEDFVP 395
++ L P + P P P+ P P+A+ P T S +
Sbjct: 1836 DEDELLP-LIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS 1894
Query: 396 DDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEA 431
D+ + +D+T A ++ A AA+ D + +A
Sbjct: 1895 DESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKA 1930
Score = 35.0 bits (79), Expect = 0.25
Identities = 82/325 (25%), Positives = 116/325 (35%), Gaps = 52/325 (16%)
Query: 287 AANGQSPSPGSQSPVVP---AGAVSTGSSSPGTPQPAP------QLPLNAAPPSSVPPVP 337
A + P P +++ V+P A +V+ PG P P Q PL+AA +S P P
Sbjct: 11 ATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSP 70
Query: 338 PSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDD 397
+ A P P P+ S GT+ AP P +P GP S
Sbjct: 71 STIASTP---LEVPFPQSS-----SGTALPLGTAPEAPTFLPNLIGPPI--SPAALALAS 120
Query: 398 RLDRSFLEDTTPARDEKKVGAKA---AQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGS 454
+ L+ T + + A A Q+ S L P VA + GS
Sbjct: 121 PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAES---------GS 171
Query: 455 PPLPAGPV-PSQDITLSSEEEAEVAAPTKG-PAP------APQQCSEPETKWSSIPASKP 506
+ P+ PS+ T ++ +EV KG P+P P C P S AS P
Sbjct: 172 VITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLP 231
Query: 507 RRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQML 566
+ T PT T A P+ + +T + P S S P P AA L
Sbjct: 232 Q--TTPTTTLA---------IASPQVKDTTISSVLISP--QNPGSLSLKGPVSPPAALSL 278
Query: 567 SFVMDDPDFESEGSDTQRRADDFPV 591
S S+ + DFP+
Sbjct: 279 STQSLPVVTSSQKTAGPNTPPDFPI 303
Score = 32.0 bits (71), Expect = 2.1
Identities = 45/175 (25%), Positives = 62/175 (35%), Gaps = 31/175 (17%)
Query: 281 GHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQ----LPLNAAPPSSVPPV 336
G PL+ +P Q S SP P P+ PL AA V P
Sbjct: 1725 GSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK 1784
Query: 337 PPSEAL-----PPPACPSAPAPRRSIISR---------LFGTSPATEAAPP--------- 373
P S ++ PP + P AP+P ++ + L SP+ AP
Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLI 1844
Query: 374 PPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSD 428
PPEP+ G QSV +P + T A+ K + +SDSD
Sbjct: 1845 PPEPI---SGGVPFQSVLVNMPTPK-SAGIPVPTPSAKQPVTKNNKGSGTESDSD 1895
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 65.5 bits (158), Expect = 2e-10
Identities = 102/428 (23%), Positives = 152/428 (35%), Gaps = 70/428 (16%)
Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP-------PSE 340
AN + S S+ P A +TG + P L PPS+ VP P+
Sbjct: 1714 ANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPAT 1773
Query: 341 ALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLD 400
P PA SAP P ++ L TS AP P P+ A+V +
Sbjct: 1774 LTPVPASTSAPVPASTLAPVLASTS-----APVPASPLAPVSASASVSA----------- 1817
Query: 401 RSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAG 460
+ PA + AA S + A P++A S P
Sbjct: 1818 ------SVPAST-----SAAAITSSSAPASAPAPTPILASV------------STPASVT 1854
Query: 461 PVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGT--APTRTAAP 518
+ S I + + A +APT PAPA + P +IPAS P AP +AP
Sbjct: 1855 ILASASIPILASALASTSAPT--PAPAASSPAAPVITAPTIPASAPTASVPLAPASASAP 1912
Query: 519 -PWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLS--------FV 569
P P VS + +P + ++S+S + P + ++ S +V
Sbjct: 1913 APAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYV 1972
Query: 570 MDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDE---GPAEPPPPPKLPLPAFRLKNDSD 626
++ S A+ + + P V ++ GP PP PP + L +
Sbjct: 1973 ASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTS--- 2029
Query: 627 LFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKE 686
FG G K E G E T + + G E E +KS DK +
Sbjct: 2030 -FGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLS----EKSADKIPEPK 2084
Query: 687 ERRRRQQR 694
E+R++Q R
Sbjct: 2085 EQRQKQPR 2092
Score = 49.7 bits (117), Expect = 1e-05
Identities = 93/448 (20%), Positives = 156/448 (34%), Gaps = 93/448 (20%)
Query: 334 PPVPPSEALPPPACPS--APAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVE 391
P VPP++ P A P APAP+ ++ G + + P+ + + E
Sbjct: 97 PEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSQFQQEFPSLQAAGDQEKKE 156
Query: 392 DFVPDDRLDRS-FLEDTTPA--RDEKKVGAKAAQQDSDSDGEALGGNPMVAGF--QDDVD 446
DD L A RD K A + SD D + G + AG Q+D+
Sbjct: 157 KETNDDNYGPGPSLRPPNVACWRDGGK--AAGSPSSSDQDEKLPGQDESTAGTSEQNDIL 214
Query: 447 LEDQPRGSPPLPAGPVPSQDITLSSEEEAEVA------------APTKGPAPAPQQCSEP 494
+ R + P + Q L+S+ A + P GP P SE
Sbjct: 215 KVVEKRIACGPPQAKLNGQQAALASQYRAMMPPYMFQQYPRMTYPPLHGPMRFPPSLSET 274
Query: 495 ETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPE---------KRSSTRPPAEMEPG 545
RG P+ + P P +S E + A+ME
Sbjct: 275 NKGLRG-------RGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVD 327
Query: 546 KGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGP 605
EQ + S+ D +G + + + + E +GS ++ D+ S+ + P
Sbjct: 328 YTEQLNFSDDDEQGSNSPK-------ENNSEDQGSKASENNENKKETDEVSNTKSSSQIP 380
Query: 606 AEP-----------------------PPPPKL------------------PLPAFRLKND 624
A+P PPPPKL P P+ + D
Sbjct: 381 AQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVAD 440
Query: 625 SDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSK----D 680
D + + ++ SE + K +++++++ +E+ + A +K K K +
Sbjct: 441 ED----EIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE 496
Query: 681 KEEGKEERRRRQQRPPRSRERTAADELE 708
K+ EE R R++ R RE+ E E
Sbjct: 497 KQPSPEEIREREREKEREREKELEKEQE 524
Score = 49.3 bits (116), Expect = 1e-05
Identities = 104/480 (21%), Positives = 170/480 (35%), Gaps = 52/480 (10%)
Query: 250 MDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVST 309
+ A ++ ++ET D NYG + A G SPS Q +P ST
Sbjct: 146 LQAAGDQEKKEKETNDDNYGPGPSLRPPNVACWRDGGKAAG-SPSSSDQDEKLPGQDEST 204
Query: 310 GSSSP--------------GTPQP---APQLPLNAAPPSSVPPVPPSEALPPPACPSAPA 352
+S G PQ Q L + + +PP + P P
Sbjct: 205 AGTSEQNDILKVVEKRIACGPPQAKLNGQQAALASQYRAMMPPYM-FQQYPRMTYPPLHG 263
Query: 353 PRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARD 412
P R S L T+ PPP E P+ + S + D+ D E D
Sbjct: 264 PMRFPPS-LSETNKGLRGRGPPPSWASEPERPS-ILSASELKELDKFDNLDAE-----AD 316
Query: 413 EKKVGAKA----AQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDIT 468
E GA+ +Q + SD + G N + + EDQ G S++
Sbjct: 317 EGWAGAQMEVDYTEQLNFSDDDEQGSNS-----PKENNSEDQ---------GSKASENN- 361
Query: 469 LSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRT 528
+++E + + TK + P Q S + + P+ RGT+ + PP P ++ +
Sbjct: 362 -ENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTS---SHLPPPPKLLAQQH 417
Query: 529 GPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADD 588
P R + P K + A E + +S ++ E + +
Sbjct: 418 PPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQR 477
Query: 589 FPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGK 648
+ DE G E P P+ R K L E+ +E E +
Sbjct: 478 KAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRER 537
Query: 649 TPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELE 708
KEK+ +K++ K+ E +K+ K +K K+ E KE+ + Q+ + +E E E
Sbjct: 538 QQEKEKELEKEQEKQRE---MEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKERE 594
Score = 49.3 bits (116), Expect = 1e-05
Identities = 58/237 (24%), Positives = 81/237 (34%), Gaps = 52/237 (21%)
Query: 274 MMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSV 333
+ +A+S PLA+ +P P S S VPA ST + P T P P P S++
Sbjct: 1737 IQQAQSSASVPPLAS---APLPPSTSASVPA---STSAPLPATLTPVPASTSAPVPASTL 1790
Query: 334 PPVPPSEALPPPACPSAPAPRRSIISRLFGTS-----------PATEAAPPP-------- 374
PV S + P PA P AP + +S S PA+ AP P
Sbjct: 1791 APVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTP 1850
Query: 375 -----------------------PEPVPAAEGPA----TVQSVEDFVPDDRLDRSFLEDT 407
P P PAA PA T ++ P + + +
Sbjct: 1851 ASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASAS 1910
Query: 408 TPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPS 464
PA V A + + +A P+ Q QP S LP+ P+
Sbjct: 1911 APAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPN 1967
Score = 35.4 bits (80), Expect = 0.19
Identities = 114/584 (19%), Positives = 191/584 (32%), Gaps = 121/584 (20%)
Query: 232 LQLQRETLLRQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQ 291
L+ +RE L ++E + +++ +E+ + + +F RS A+P+ +
Sbjct: 589 LEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETE 648
Query: 292 SPSPGSQSPVVPAGAVSTGSSS----------PGTPQPAPQLPLNAAPPSSVPPVPPSEA 341
S P V +G S Q Q P +VP P S
Sbjct: 649 PESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSST 708
Query: 342 LPPPA-----CPSAPAPRR---------------SIISRLFGTSPATEAAP-----PPPE 376
+PPP P P P+ + R+ PA + P PP+
Sbjct: 709 VPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPK 768
Query: 377 PVPAAE----GPATVQSVEDFVPDDR------LDRSFLEDTTP---ARDEKKVGAKAAQQ 423
P+ + P + +S E R + L + P A ++ KA ++
Sbjct: 769 PLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEE 828
Query: 424 DSDSDGE-ALGGNPMVAGFQ-DDVDLEDQPRGSPPLPAGPVPSQDI------------TL 469
D E AL + A + + LE P+ + Q T
Sbjct: 829 PEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTD 888
Query: 470 SSEEEAEVAAPTKGPAPAPQQ------CSEPETKWS-----------SIPASKPRRGTAP 512
++ + A AP + APQ+ S+P K S S+P G
Sbjct: 889 ANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPK 948
Query: 513 TRTAA-------------PPWPGGVSVRTGP------EKRSSTRPPAEMEPGKGEQASSS 553
+ P G + GP + +S TR + E+ +
Sbjct: 949 VTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDR 1008
Query: 554 ESDPEGPIAAQMLSFVMDDPD--FESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPP 611
GPI +L + ++ + E EG ++ + V+ P +D P PPPP
Sbjct: 1009 PVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVK--PEKTEKKDLPP--PPPP 1064
Query: 612 PKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKK 671
P+ P P + EA S+E + PS++ +K + + + A K
Sbjct: 1065 PQPPAPIQPQSVPPPI----QPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVK 1120
Query: 672 K----------SKHKKSKDKEEGKE---ERRRRQQRPPRSRERT 702
K +K +K K+ ER R RP +E T
Sbjct: 1121 TVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKEST 1164
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 65.5 bits (158), Expect = 2e-10
Identities = 96/337 (28%), Positives = 130/337 (38%), Gaps = 56/337 (16%)
Query: 307 VSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP--PACPSAPAPRRSIISRLFGT 364
+ +G P Q PL+ PP SVPP P+ L P PA P+ P P S FG
Sbjct: 1289 LKSGKRHPPLYQAGLTPPLS--PPKSVPPSVPARGLQPQPPATPAVPHPPPS---GAFGL 1343
Query: 365 SPATEAAPPPPEPVPAAEG-----PATVQSVEDFVPDDRLDRSFLEDTTPA---RDEKKV 416
A EAA +EG P+ + + D+ L R+ +T P+ +E V
Sbjct: 1344 GGALEAAE--------SEGLGLGCPSPCKRL-----DEELKRNL--ETLPSFSSDEEDSV 1388
Query: 417 GAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPR-------GSPPLPAGPVPSQDITL 469
Q+S S + +P +AG +D + P G PPLP P + + T
Sbjct: 1389 AKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTP 1448
Query: 470 SSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTG 529
E PT PAP PQ P P APT ++ PP P +
Sbjct: 1449 EPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPP--LPPPPP 1506
Query: 530 PEKRSSTRPP----AEMEPGKGEQASSSESDPEGP------IAAQMLSFVM----DDPDF 575
P S PP A + E A+ S DPE P +A + + + D+
Sbjct: 1507 PAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAG 1566
Query: 576 ESEGSDTQRRADDFPVR--DDPSDVTDEDEGPAEPPP 610
ES G R D+F +R D PS G EPPP
Sbjct: 1567 ESGGEGIFRERDEFVIRAEDIPSLKLALQTG-REPPP 1602
Score = 54.3 bits (129), Expect = 4e-07
Identities = 64/221 (28%), Positives = 81/221 (36%), Gaps = 41/221 (18%)
Query: 237 ETLLRQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPG 296
E L R LET L ++ EE SV + + Q + A S PLA + +P
Sbjct: 1368 EELKRNLET--LPSFSSDEEDSVAKNRDLQE-----SISSAISALDDPPLAGPKDTSTPD 1420
Query: 297 SQSPVVPAGAVSTGSSSPGTPQPAPQLP------------LNAAPPSSVPPVPPSEALPP 344
P+ PA AV PG P P P LP L PP + PP P + PP
Sbjct: 1421 GP-PLAPAAAV------PGPP-PLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP 1472
Query: 345 PACPSAPAPRRSIISRLFGTSPATEAAPP-----------PPEPVPAAEGPATVQSVEDF 393
P P P P L +P++ PP PP P P A P E
Sbjct: 1473 PP-PPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPA 1531
Query: 394 VPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGG 434
P + L DT P KK A ++D + GG
Sbjct: 1532 APSP--EDPELPDTRPLHLAKKQETAAVCGETDEEAGESGG 1570
Score = 53.9 bits (128), Expect = 5e-07
Identities = 86/343 (25%), Positives = 120/343 (34%), Gaps = 75/343 (21%)
Query: 285 PLAANGQSPSPG----SQSPVVPAGAVSTGSSSPGTPQPAPQLPLN---AAPPSSVPPVP 337
P A + +P P P P P P P P LP AP S PP P
Sbjct: 1440 PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP 1499
Query: 338 PSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPE--------PVPAAE------- 382
P PPPA PS P P + L +P E A P PE P+ A+
Sbjct: 1500 PLPPPPPPAMPSPPPPPPPAAAPL--AAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAV 1557
Query: 383 ------------GPATVQSVEDFV--------------------PDDRLDRSFLEDTTPA 410
G + ++FV P R+ ++ L+ TP
Sbjct: 1558 CGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPE 1617
Query: 411 RDEKKVGAKAAQQDSDSDGEALGG-NPMVAGFQDDVDLEDQPR--GSPPLPAGPVPSQDI 467
+ + A G+A + F ++V+ +D R P PVP +
Sbjct: 1618 IKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVP---V 1674
Query: 468 TLSSEEEAEVAA------PTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWP 521
S + + V+A P K PAP P +PET + KP T T PP P
Sbjct: 1675 RRSGQAKNPVSAGGSSAPPPKAPAPPP----KPETP-EKTTSEKPPEQTPETAMPEPPAP 1729
Query: 522 GGVSVRTGPEKRSSTRPPAEME-PGKGEQASSS-ESDPEGPIA 562
S+ EK E P +GE+A+S ++ PE +A
Sbjct: 1730 EKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLA 1772
Score = 40.4 bits (93), Expect = 0.006
Identities = 96/411 (23%), Positives = 140/411 (34%), Gaps = 96/411 (23%)
Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLP---------------LNAAPPSS 332
++ SPSP + V +T +P P P P P L A PS
Sbjct: 807 SHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPS- 865
Query: 333 VPPVPPSEALPPPAC---------PSAPAPRRSIIS--RLFGTSPATEAAPPPPEPVPAA 381
P + P E+L PP P PAP + + G PA P P+
Sbjct: 866 -PRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQ---GT 921
Query: 382 EGPATVQSVEDFVPDDRL---DRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMV 438
+ P V PD L +RSF P +E G A D G+A G P
Sbjct: 922 KAPRFVPLTSICFPDSLLQDEERSFF----PTMEEMFGGGAA-----DDYGKA--GPP-- 968
Query: 439 AGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGP-APAPQQCSEPETK 497
ED+ G P AGP P A GP P + PET
Sbjct: 969 ---------EDE--GDPKAGAGPPPGPP-----------AYDPYGPYCPGRASGAGPETP 1006
Query: 498 WSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDP 557
+ +KP P+ A P +++GP + + PP P + S+P
Sbjct: 1007 GLGLDPNKPPE--LPSTVNAEPLG---LIQSGPHQAAPPPPPPPPPP------PAPASEP 1055
Query: 558 EGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDV------TDEDEGPAEPPP- 610
+G + + + ++ RR D P P + + DE A+ P
Sbjct: 1056 KGGLTSPIFCSTKPKKLLKTSSFHLLRRRD--PPFQTPKKLYAQEYEFEADEDKADVPAD 1113
Query: 611 ----PPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEG--KEGKTPSKEKK 655
P +LP ++ L LG + P +G + G+ P+K K+
Sbjct: 1114 IRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKR 1164
Score = 40.0 bits (92), Expect = 0.008
Identities = 64/287 (22%), Positives = 91/287 (31%), Gaps = 25/287 (8%)
Query: 290 GQSPSPGSQSPVVPAGAVSTGSSSP-GTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP 348
G + G P G G+ P G P P P S P P L P P
Sbjct: 957 GAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPP 1016
Query: 349 SAPAPRRSIISRLFGTSPATEAAPPP----PEPVPAAE--GPATVQSVEDFVPDDRLDRS 402
P+ + L + P A PPP P P PA+E G T P L S
Sbjct: 1017 ELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTS 1076
Query: 403 ----FLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLP 458
P + KK+ A+ + ++D D + D+ PR P L
Sbjct: 1077 SFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADV-----------PADIRLNPRRLPDLV 1125
Query: 459 AGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAP 518
+ LS + + P GP P++ TK +PR P
Sbjct: 1126 SS--CRSRPALSPLGDIDFCPPNPGP-DGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVP 1182
Query: 519 PWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQM 565
G S T + R K E+A + +P P+ ++
Sbjct: 1183 TTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKL 1229
Score = 32.3 bits (72), Expect = 1.6
Identities = 64/271 (23%), Positives = 76/271 (28%), Gaps = 41/271 (15%)
Query: 287 AANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPP---VPPSEALP 343
A G S P S + S GS P P P PP S P + P + L
Sbjct: 135 ALPGSSTFPSSSALSAYQHPASFGSR----PFPVPSSLSLQDPPFSPPANGLLSPHDVLH 190
Query: 344 PPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSF 403
+ P RL G A P + P GP PD
Sbjct: 191 LKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGP----------PDPPPPPRH 240
Query: 404 LEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVP 463
L A AA+Q S G P PP P +P
Sbjct: 241 LPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAP-----------------GPPPPERALP 283
Query: 464 SQDITLSSEEEAEVAAPTKGPAPAPQ-----QC--SEPETKWSSIPASKPRRGTAPTRTA 516
QD + + A P P PA C S P + A P G P+ A
Sbjct: 284 RQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGA 343
Query: 517 APPWPGGVSVRTGPEKRSSTRPPAEMEPGKG 547
P G S T +T P A G G
Sbjct: 344 GEPSKAGPSGATAGASGRATGPEAAGGGGAG 374
Score = 30.0 bits (66), Expect = 7.9
Identities = 16/60 (26%), Positives = 24/60 (40%)
Query: 595 PSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEK 654
P+ GP +PPPPP+ F L S E++ P+ + G P E+
Sbjct: 221 PAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPER 280
Score = 30.0 bits (66), Expect = 7.9
Identities = 85/376 (22%), Positives = 124/376 (32%), Gaps = 55/376 (14%)
Query: 278 RSRGHASPLA-ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPV 336
RSR SPL + P+PG P G T + G P+P + + P VP
Sbjct: 1129 RSRPALSPLGDIDFCPPNPGPDGPR-RRGRKPTKAKRDGPPRPRGRPRIR---PLEVPTT 1184
Query: 337 P-PSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVP-----AAEGPAT---- 386
P+ A P P R R + T P P + A EG T
Sbjct: 1185 AGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGD 1244
Query: 387 -VQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGN--PMV-AGFQ 442
+ + D L R +E +EK+ K+ S D G P+ AG
Sbjct: 1245 AISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLT 1304
Query: 443 DDVD-------------LEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKG-----P 484
+ L+ QP +P +P P PS L EA A ++G P
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPAVPHPP-PSGAFGLGGALEA---AESEGLGLGCP 1360
Query: 485 APAPQQCSEPETKWSSIPA--SKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEM 542
+P + E + ++P+ S A R +S P P +
Sbjct: 1361 SPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAG----PKDT 1416
Query: 543 EPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDED 602
G + + + P P + P S G+ ++ P P T +
Sbjct: 1417 STPDGPPLAPAAAVPGPPPLPGL-------PSANSNGTPEPPLLEEKPPPTPPPAPTPQP 1469
Query: 603 EGPAEPPPP-PKLPLP 617
+ P PPPP P LP P
Sbjct: 1470 QPPPPPPPPQPALPSP 1485
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 64.7 bits (156), Expect = 3e-10
Identities = 122/562 (21%), Positives = 185/562 (32%), Gaps = 119/562 (21%)
Query: 228 NIPFLQLQRETLLRQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLA 287
++PF Q +L ++E + + L+ E E++N + L AR G P +
Sbjct: 479 SVPFAQ--HSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLG---ARDTGSEVP-S 532
Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLP-LNAAPP---------------S 331
+G P +P TGS PG + +P+ N A P
Sbjct: 533 GSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGG 592
Query: 332 SVPPVPPSEALPPPACPSAPAPRRSIISRLFG---------TSPATEAAPPPPEPVPAAE 382
S PP P PPP P P P + S G P + PPP P P
Sbjct: 593 SPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPP 652
Query: 383 GPATVQSVEDFVPDDRL-------------DRSFLEDTTPARDEKKVGAKAAQQDSDSDG 429
P V DRL L R K + A +A + G
Sbjct: 653 PPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLIAASAGPPGGAFG 712
Query: 430 EAL-------------------GGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLS 470
EA G + + P + PLP+ V ++ L
Sbjct: 713 EAFLPFPPPQEAAYGLPYALYAQGQEGRGAYSREAYHLPMPMAAEPLPSSSVSGEEARLP 772
Query: 471 SEEEAEVA----APTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPT------------- 513
EEAE+A PT G E K SI R
Sbjct: 773 PREEAELAEGKTLPTAGTVGRVLAMLVQEMK--SIMQRDLNRKMVENVAFGAFDQWWESK 830
Query: 514 RTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDP 573
A P+ + E + T+ EPG ++S G + +F
Sbjct: 831 EEKAKPFQNAAKQQAKEEDKEKTK---LKEPGLLSLVDWAKSG--GTTGIEAFAF----- 880
Query: 574 DFESEGSDTQRRADDFPV-RDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGL 632
G R F V R +PS++++ E K P P+ + D D
Sbjct: 881 ---GSGLRGALRLPSFKVKRKEPSEISEASE--------EKRPRPSTPAEEDED------ 923
Query: 633 EEAGPKESSEEGKEG-KTPSKEKKKKKKKGK--------EEEEKAAKKKSKHKKSKDKEE 683
+ KE+ E G+ G K P +++++ K +GK E E+A+++ S K +D EE
Sbjct: 924 DPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEE 983
Query: 684 GKEERRRRQQRPPRSRERTAAD 705
+E+ R + +E +D
Sbjct: 984 DEEDEDREEAVDTTKKETEVSD 1005
Score = 58.9 bits (141), Expect = 2e-08
Identities = 106/479 (22%), Positives = 171/479 (35%), Gaps = 85/479 (17%)
Query: 244 ETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRG-HASPLAANGQSPSPGSQSPVV 302
E + +D T +E V ++++ + A S G + S + S S S S
Sbjct: 988 EDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSS 1047
Query: 303 PAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLF 362
+ + S+ SSS + + + AA PS+ PP P +P PA P P R +
Sbjct: 1048 SSSSSSSSSSSESSSEDEEEEERPAALPSASPP-PREVPVPTPAPVEVPVPER-VAGSPV 1105
Query: 363 GTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQ 422
P EA+P P P E P + P R
Sbjct: 1106 TPLPEQEASPARPAG-PTEESPPSA---------------------PLRPP--------- 1134
Query: 423 QDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTK 482
E G P A D+ R S P+P P P + S EV
Sbjct: 1135 -------EPPAGPPAPAPRPDE-------RPSSPIPLLPPPKKRRKTVSFSAIEVV---- 1176
Query: 483 GPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEM 542
PAP P + P+ K+ + K RG T P + V++ PE+ S R
Sbjct: 1177 -PAPEPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDHASL-VKSWPEEVS--RGGRSR 1232
Query: 543 EPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDP--SDVTD 600
G+G E++P + +L+ + P +R P +D ++ +D
Sbjct: 1233 AGGRGRLTEEEEAEPGTEVDLAVLADLALTP--------ARRGLPALPAVEDSEATETSD 1284
Query: 601 EDEGP----------------AEPPPPPKLPLPAFRLKNDSDLFGLGLEEA--GPKESSE 642
E E P +P PP P + + LF +E P+
Sbjct: 1285 EAERPRPLLSHILLEHNYALAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVA 1344
Query: 643 EGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRER 701
E +E K P + ++++++ +E EE+ +++ + S +G+ RRR R R R
Sbjct: 1345 EAEEPK-PQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRR 1402
Score = 58.2 bits (139), Expect = 3e-08
Identities = 92/381 (24%), Positives = 128/381 (33%), Gaps = 60/381 (15%)
Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQP----APQLPLNAAPPSSVPPVPP 338
ASP P+P VP + SP TP P +P P A P PP P
Sbjct: 1077 ASPPPREVPVPTPAPVEVPVPERV----AGSPVTPLPEQEASPARP--AGPTEESPPSAP 1130
Query: 339 SEALPPPACPSAPAP------------------RRSIISRLFGTSPATEAAPPPPEPVPA 380
PPA P APAP RR +S F A PPP P
Sbjct: 1131 LRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVS--FSAIEVVPAPEPPPATPPQ 1188
Query: 381 AE--GPAT---VQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDS-DSDGEALGG 434
A+ GPA+ + VE + + LD + L + P + ++A + + EA G
Sbjct: 1189 AKFPGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPG 1248
Query: 435 NPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEP 494
+ D+ L RG P LPA + E E + + P P
Sbjct: 1249 TEVDLAVLADLALTPARRGLPALPA---------VEDSEATETSDEAERPRPLLSHILLE 1299
Query: 495 ETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPP---AEMEPGKGEQAS 551
++ + P AP P P ++ + P P AE E K +Q
Sbjct: 1300 HNYALAVKPTPP----APALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQ 1355
Query: 552 S--SESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPP 609
E + EG + D S+G RR R S P PP
Sbjct: 1356 QQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRR------RSLRSHARRRRPPPPPPP 1409
Query: 610 PPPKLPLPAFRLKNDSDLFGL 630
PPP+ P + + L+ +
Sbjct: 1410 PPPRAYEPRSEFEQMTILYDI 1430
Score = 42.4 bits (98), Expect = 0.002
Identities = 68/302 (22%), Positives = 99/302 (32%), Gaps = 51/302 (16%)
Query: 258 SVQQETEDQNYGIFLEMME-------------ARSRGHASPLAANGQS---PSPGSQSPV 301
S Q + D NY + E R +P A N PS S P
Sbjct: 356 SSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFPPSYTSYLPP 415
Query: 302 VPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRL 361
P+ P + P P+ P P P E + P++PA
Sbjct: 416 EPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPAR-------- 467
Query: 362 FGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAA 421
SPA E E VP A+ + +E + + R SFL T +E A
Sbjct: 468 -SGSPAPETT---NESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGA 523
Query: 422 QQDSDSDGEALGGN------PMVAGFQDDVD--------LEDQPRGSPPLPAGPVPS-QD 466
+D+ S+ + G+ P A F+D + P+ + A P S D
Sbjct: 524 -RDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDD 582
Query: 467 ITLSSEEEA----EVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTA---PTRTAAPP 519
+ +S ++ P + P P P P +S+P P A P R PP
Sbjct: 583 MEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPP 642
Query: 520 WP 521
P
Sbjct: 643 PP 644
Score = 35.4 bits (80), Expect = 0.19
Identities = 56/239 (23%), Positives = 87/239 (36%), Gaps = 36/239 (15%)
Query: 391 EDFVPDDRLDRSFLE-DTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLED 449
ED ++ +D + E + + DE+ + +DSDGE N + +
Sbjct: 986 EDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGE----NDSTSDSESSSSSSS 1041
Query: 450 QPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGP--APAPQQCSEPETKWSSIPASKPR 507
S + S + SSE+E E P P +P P++ P +P +
Sbjct: 1042 SSSSSSSSSSSSSSSSSES-SSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERV 1100
Query: 508 RGT----APTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESD--PEGPI 561
G+ P + A+P P G + + P + RPP EP G A + D P PI
Sbjct: 1101 AGSPVTPLPEQEASPARPAGPTEESPPS--APLRPP---EPPAGPPAPAPRPDERPSSPI 1155
Query: 562 AAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFR 620
++ P +R+ F +V E P PP K P PA R
Sbjct: 1156 P------LLPPP-------KKRRKTVSF----SAIEVVPAPEPPPATPPQAKFPGPASR 1197
Score = 32.3 bits (72), Expect = 1.6
Identities = 43/192 (22%), Positives = 63/192 (32%), Gaps = 31/192 (16%)
Query: 449 DQPRGSPPLPAG------PVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSE--PETKWSS 500
+ P PP P G P P ++ +S A +P + +PAP+ +E P + SS
Sbjct: 431 EAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPA---SPARSGSPAPETTNESVPFAQHSS 487
Query: 501 IP-----------------ASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEME 543
+ AS + G V +G T PPA
Sbjct: 488 LDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPA--- 544
Query: 544 PGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDE 603
P E + + S G + + S G D + DD P+ +
Sbjct: 545 PANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQP 604
Query: 604 GPAEPPPPPKLP 615
P PPPPP P
Sbjct: 605 PPPPPPPPPPPP 616
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 64.7 bits (156), Expect = 3e-10
Identities = 94/415 (22%), Positives = 151/415 (36%), Gaps = 67/415 (16%)
Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAP-QLPLNAAPPSSVPPVPPSEALPPP- 345
AN + S GS+ P++P G ST S+ P +P P + P+ + S PP P +PPP
Sbjct: 115 ANRDNDSGGSRPPLLPPGGRST-SAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPR 173
Query: 346 ----ACPSAPAPRRSIISRLFGTSPATEAAPP----PPEPVPAAEGPATVQSVEDFVPDD 397
+ P + P R +SP +PP P +P P P + +
Sbjct: 174 PDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233
Query: 398 RLDRSFLEDTTPARDEKKV---GAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGS 454
+ +S L ++P + + ++A +G P + ++ V
Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI--HREAVPPPPPQNNK 291
Query: 455 PPLPAGPVPSQDITLSSEEEAEVAAPTK-GPAPAPQQCSEPETKWSSIPASKPRRGTAPT 513
PP+P+ P PS SS+ P++ GP P P P + + P+R + +
Sbjct: 292 PPVPSTPRPS----ASSQAPPPPPPPSRPGPPPLP-----PSSSGNDETPRLPQRNLSLS 342
Query: 514 RTAAP-PWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDD 572
+ P P PG R+GP + P E+ DP G S +
Sbjct: 343 SSTPPLPSPG----RSGP-----------LPPPPSERPPPPVRDPPG------RSGPLPP 381
Query: 573 PDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPP-------PKLPLPAFRLKN-- 623
P S T R P S V GP P PP P P P+ ++N
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGF 441
Query: 624 ---------DSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAA 669
+S + + + P E + + PSK + + + G E+ A
Sbjct: 442 QDSPCEDEWESRFYFHPISDLPPPEPYVQTTK-SYPSKLARNESRSGSNRRERGA 495
Score = 33.9 bits (76), Expect = 0.55
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 17/104 (16%)
Query: 281 GHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE 340
G + PL GS S +PA S +P+ P+ PL PP PS
Sbjct: 374 GRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL--------PPDRPSA 425
Query: 341 ALPPPACPSA-------PAPRRSIISRLFGTSPATEAAPPPPEP 377
PPP PS +P F P ++ PPPEP
Sbjct: 426 GAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDL--PPPEP 467
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 64.7 bits (156), Expect = 3e-10
Identities = 94/415 (22%), Positives = 151/415 (36%), Gaps = 67/415 (16%)
Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAP-QLPLNAAPPSSVPPVPPSEALPPP- 345
AN + S GS+ P++P G ST S+ P +P P + P+ + S PP P +PPP
Sbjct: 115 ANRDNDSGGSRPPLLPPGGRST-SAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPR 173
Query: 346 ----ACPSAPAPRRSIISRLFGTSPATEAAPP----PPEPVPAAEGPATVQSVEDFVPDD 397
+ P + P R +SP +PP P +P P P + +
Sbjct: 174 PDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233
Query: 398 RLDRSFLEDTTPARDEKKV---GAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGS 454
+ +S L ++P + + ++A +G P + ++ V
Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI--HREAVPPPPPQNNK 291
Query: 455 PPLPAGPVPSQDITLSSEEEAEVAAPTK-GPAPAPQQCSEPETKWSSIPASKPRRGTAPT 513
PP+P+ P PS SS+ P++ GP P P P + + P+R + +
Sbjct: 292 PPVPSTPRPS----ASSQAPPPPPPPSRPGPPPLP-----PSSSGNDETPRLPQRNLSLS 342
Query: 514 RTAAP-PWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDD 572
+ P P PG R+GP + P E+ DP G S +
Sbjct: 343 SSTPPLPSPG----RSGP-----------LPPPPSERPPPPVRDPPG------RSGPLPP 381
Query: 573 PDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPP-------PKLPLPAFRLKN-- 623
P S T R P S V GP P PP P P P+ ++N
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGF 441
Query: 624 ---------DSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAA 669
+S + + + P E + + PSK + + + G E+ A
Sbjct: 442 QDSPCEDEWESRFYFHPISDLPPPEPYVQTTK-SYPSKLARNESRSGSNRRERGA 495
Score = 33.9 bits (76), Expect = 0.55
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 17/104 (16%)
Query: 281 GHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE 340
G + PL GS S +PA S +P+ P+ PL PP PS
Sbjct: 374 GRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL--------PPDRPSA 425
Query: 341 ALPPPACPSA-------PAPRRSIISRLFGTSPATEAAPPPPEP 377
PPP PS +P F P ++ PPPEP
Sbjct: 426 GAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDL--PPPEP 467
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 64.7 bits (156), Expect = 3e-10
Identities = 107/500 (21%), Positives = 175/500 (35%), Gaps = 85/500 (17%)
Query: 272 LEMME--ARSRGHASP------LAANGQSPSPGSQSPVV------PAGAVSTGSSSPGTP 317
L+M E RS GH+S + G S + SPV+ P+ S+ +SSP
Sbjct: 1369 LDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMK 1428
Query: 318 QPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRL-------FGTSPATEA 370
P+ P + S P + P S +P I R +SP +A
Sbjct: 1429 DGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKA 1488
Query: 371 APPPPEP---------------VPAAEGPATVQSVED-FVPDDRLDRSFLEDTTPARDEK 414
P P P P E + SV+ V L + ++ D K
Sbjct: 1489 LPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVK 1548
Query: 415 KVGAKAAQQDSDS--DGEALGGNPMV----AGFQDDVD-----------------LEDQP 451
+ + +SDS D +A P+ +G +VD ++D+P
Sbjct: 1549 PSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP 1608
Query: 452 RGSPPLPAG----PVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPR 507
R +P +G P P + + + +KG P+P+ S E S P P+
Sbjct: 1609 RAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE----SSPEHPPK 1664
Query: 508 RGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPP-----AEMEPGKGEQASSSESDPEGPIA 562
TA + + P P S RT P +RSS P A + +SS E+ P
Sbjct: 1665 SRTARRGSRSSPEPKTKS-RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723
Query: 563 AQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLK 622
+ V E S +RR+ P T G + P P L R +
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRS-----ASSPRTKTTSRRGRSPSPKPRGLQRSRSRSR 1778
Query: 623 NDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKE 682
+ + +G +S+ ++ ++++ G ++ ++ + S
Sbjct: 1779 REKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTS---- 1834
Query: 683 EGKEERRRRQQRPPRSRERT 702
RR R + PP SR+R+
Sbjct: 1835 --SRRRRGRSRTPPTSRKRS 1852
Score = 60.5 bits (145), Expect = 5e-09
Identities = 90/458 (19%), Positives = 161/458 (35%), Gaps = 73/458 (15%)
Query: 279 SRGHASPLAANGQSP-SPGSQSPVVPAGAVSTGSSSP-------------GTPQPAPQLP 324
SR +P +AN P S + +PV AG+ + + +P G +P++P
Sbjct: 2327 SRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP 2386
Query: 325 LNAAPPSSVPPVPP----SEALPPPACPS--------APAPRRSIISRLFGTSPATEAAP 372
L+A S PP + + PP+ PS AP+P S G +P+ P
Sbjct: 2387 LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP-----SSRMGQAPSQSLLP 2441
Query: 373 P----PPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSD 428
P P PVP+A + R + TTP + + + A + S
Sbjct: 2442 PAQDQPRSPVPSAFSDQS--------------RCLIAQTTPVAGSQSLSSGAVATTTSSA 2487
Query: 429 GEALGGNPMVAGFQDDVDLEDQPRGS----PPLPAGPVPSQDITLSSEEEAEVAAPTKGP 484
G+ G + A D+ + P + P A P+++ SS + ++ +
Sbjct: 2488 GDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSS 2547
Query: 485 APAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGV-SVRTGPEKRSSTRPPAEME 543
+ + S + S +S P + + P P +VR G R PA+ +
Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREG---RPPEPTPAKRK 2604
Query: 544 PGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDE 603
+SSS S ++ S S S + + P + P +
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP-QALPKPA 2663
Query: 604 GPAEPPP------PPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKK 657
P +PPP P+ P+ + R + P+ S P ++
Sbjct: 2664 SPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPS---------PRDQQSSS 2714
Query: 658 KKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRP 695
++G ++ + HK+ ++ + R R + P
Sbjct: 2715 SERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 55.1 bits (131), Expect = 2e-07
Identities = 100/461 (21%), Positives = 156/461 (33%), Gaps = 53/461 (11%)
Query: 287 AANGQSPSP--GSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALP- 343
+A SPSP S P PA G+PQP PL+ P + PPSEA P
Sbjct: 346 SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN-----PPSEASPT 400
Query: 344 ----PPACP-----------SAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQ 388
PP P S P+P+ + +SR +SP + P P P P + +
Sbjct: 401 RDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES----PKPAPAPGSHREISSS 456
Query: 389 SVEDFVPDDRLDRSFLEDTTPA----RDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDD 444
R R TP+ R AK + S + + ++
Sbjct: 457 PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRS 516
Query: 445 VDLEDQPRGSPPLPAGPVPS-QDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPA 503
+ R P G S Q S + ++ P T+ S
Sbjct: 517 RSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSR 576
Query: 504 SKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAA 563
+ RRG + +RT P RT +RS +R PA + + S P+
Sbjct: 577 TPARRGRSRSRT---PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRR 633
Query: 564 QMLSFVMDDPDFESEGSDTQRRA---DDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFR 620
+ S S RR P R S PA + PA R
Sbjct: 634 RSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS----RSRTPARRSGRSRSRTPARR 689
Query: 621 LKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEK----AAKKKSKHK 676
++ S G S + G++ S+ +++ + G E K ++++S+
Sbjct: 690 GRSRS-----RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSN 744
Query: 677 KSKDKEEGK-EERRRRQQRPPRSRERTAADELEAFLGGGAP 716
S + ++ + RR R PRS+ ++ L L G +P
Sbjct: 745 SSPEMKKSRISSRRSRSLSSPRSKAKSRL-SLRRSLSGSSP 784
Score = 50.1 bits (118), Expect = 7e-06
Identities = 97/430 (22%), Positives = 136/430 (31%), Gaps = 76/430 (17%)
Query: 296 GSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRR 355
G+++P A TGS GTP A P + S P P S L P A AP
Sbjct: 2299 GARTPAALAALSLTGS---GTPPTAANYPSS----SRTPQAPASANLVGPRSAHATAPVN 2351
Query: 356 SIISRLFGTSPATEAAPPPPEPVPAAEGPA--------------TVQSVEDFVPDDRLDR 401
SR T AA P A PA + V LDR
Sbjct: 2352 IAGSR-------TAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDR 2404
Query: 402 SFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGP 461
+ A + ++ ++ A S G+A + + +DQPR P
Sbjct: 2405 ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPA-------QDQPRS-------P 2450
Query: 462 VPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPA-------SKPRRGTAPTR 514
VPS S + +A T P Q S ++ A S P G +
Sbjct: 2451 VPS---AFSDQSRCLIAQTT--PVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505
Query: 515 TAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPD 574
PP TG ++ S+ A ++P K ++SSS S ++ S
Sbjct: 2506 VGEPP------ASTGAQQPSAL---AALQPAKERRSSSSSSSSSSSSSSSSSS---SSSS 2553
Query: 575 FESEGSDTQRRADDFPVRDD------PSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLF 628
S S + PV+ + PS E E PP P PA R + S
Sbjct: 2554 SSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE--PTPAKRKRRSSSSS 2611
Query: 629 GLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKK--KSKHKKSKDKEEGKE 686
+ SS + S AK ++ K + K+
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671
Query: 687 ERRRRQQRPP 696
ERR R R P
Sbjct: 2672 ERRSRSPRKP 2681
Score = 46.2 bits (108), Expect = 1e-04
Identities = 40/121 (33%), Positives = 57/121 (47%), Gaps = 14/121 (11%)
Query: 594 DPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGK--EGKTPS 651
DP E + PA P PPK P ++ S ++ K+ + G+ E +P
Sbjct: 152 DPQRRAREAKQPA--PEPPK---PYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
Query: 652 KEKKK---KKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRP-PRSR---ERTAA 704
+E+KK KKK E E K K +S KSK K + K+ +R R P P+SR T+A
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA 266
Query: 705 D 705
D
Sbjct: 267 D 267
Score = 42.0 bits (97), Expect = 0.002
Identities = 78/384 (20%), Positives = 134/384 (34%), Gaps = 49/384 (12%)
Query: 367 ATEAAPPPPEPVP-----AAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAA 421
A + AP PP+P ++ T + + DR RS E ++P R+ KK K
Sbjct: 160 AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRS--ESSSPRRERKKSSKKKK 217
Query: 422 QQDSDSDGEALGGNPMVAGFQDDVDLE-DQPRGSPPLP----------AGPVPSQDITLS 470
+ + +P + D + + R + P P A S D + S
Sbjct: 218 HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS 277
Query: 471 SEEEAEVAAPT-----KGPAPAPQQCSEPETKWSSIPASKPRRGTAP-TRTAAPPWPGGV 524
A T + P+PA + E + +S + +R ++P T T P P
Sbjct: 278 RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
Query: 525 SVRTGPEKRSSTRPPAEME--------PGKGEQASSSESDPEGPIAAQMLSFVMDDPDFE 576
+ EK S+TRP E P + P+A LS +P
Sbjct: 338 KDKDKKEK-SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPP-- 394
Query: 577 SEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPP--------PKLPLPAFRLKNDSDLF 628
SE S T+ R+ P + E P+ P P+ P PA + ++
Sbjct: 395 SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 629 GLGLEEAGPKESSEEGKE-GKTPSKEKKKKK-----KKGKEEEEKAAKKKSKHKKSKDKE 682
+ ++ K TPS+ + + K+G+ K+ +S
Sbjct: 455 SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR 514
Query: 683 EGKEERRRRQQRPPRSRERTAADE 706
+ +R + R P+ R R+ + +
Sbjct: 515 RSRSAQRWGRSRSPQRRGRSRSPQ 538
Score = 41.6 bits (96), Expect = 0.003
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 5/106 (4%)
Query: 278 RSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP 337
R R +S +++ S S S S + + S+ SSS + + P A P P P
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Query: 338 PSEALPPPACPSAPAPRRSI----ISRLFGTSPATEAAPPPPEPVP 379
S PPP + +PR+ I SR SP E P P+P P
Sbjct: 2663 ASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSP-VERRRPSPQPSP 2707
Score = 40.8 bits (94), Expect = 0.005
Identities = 64/306 (20%), Positives = 109/306 (35%), Gaps = 28/306 (9%)
Query: 277 ARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPV 336
+R +P + SP +S ++P + S GSSSP T + P+ P + S+ P
Sbjct: 939 SRVTSRTTPRRSRSVSPCSNVESRLLPRYSHS-GSSSPDT-KVKPETPPRQSHSGSISPY 996
Query: 337 PPSEALPPPACPS-----APAPRRSIISRLFGTSPAT-------EAAPPPPEPVPAAEGP 384
P +A PP PS +P P+ L + P + +++ PP E
Sbjct: 997 PKVKAQTPPG-PSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSS- 1054
Query: 385 ATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDD 444
++ PD R D S E + + +K+ Q S G + +P+
Sbjct: 1055 LQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKS--QTSPKGGRSRSSSPVTELASRS 1112
Query: 445 VDLEDQPR--GSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIP 502
+D+ SP L +G P Q S + + +E + K + P
Sbjct: 1113 PIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPP 1172
Query: 503 ASKPRRGTAPTRTAAPPWPGGVSVRTGPEK----RSSTRPPAEMEPGKGEQASSSESDPE 558
+ P+P V+ PE + + R P G G + E +
Sbjct: 1173 QEDATASPPRQKDKFSPFP----VQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA 1228
Query: 559 GPIAAQ 564
P ++Q
Sbjct: 1229 LPTSSQ 1234
Score = 40.4 bits (93), Expect = 0.006
Identities = 57/253 (22%), Positives = 85/253 (33%), Gaps = 29/253 (11%)
Query: 452 RGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTA 511
R S P A PS +++ E +A P+P+P++ S + P R G +
Sbjct: 320 RPSSPETATKQPSSPYEDKDKDKKEKSATR--PSPSPERSSTGPEPPAPTPLLAERHGGS 377
Query: 512 PTRTAAPPWPGGVSVRTGPEKRSSTR---PPAEMEPGKGEQASSSESDPEGPIAAQMLSF 568
P A P P + S TR PP P K Q+SSSES P P
Sbjct: 378 PQPLATTPL--SQEPVNPPSEASPTRDRSPPKS--PEKLPQSSSSESSPPSP-------- 425
Query: 569 VMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLF 628
+ + R A P P+ + P R K D
Sbjct: 426 ---------QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKN--RSHGRAKRDKSHS 474
Query: 629 GLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEER 688
G S K G++ S+ K+ + + + +S + + + + R
Sbjct: 475 HTPSRRMGRSRSPATAKRGRSRSR-TPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGR 533
Query: 689 RRRQQRPPRSRER 701
R QRP SR R
Sbjct: 534 SRSPQRPGWSRSR 546
Score = 36.2 bits (82), Expect = 0.11
Identities = 52/241 (21%), Positives = 86/241 (35%), Gaps = 25/241 (10%)
Query: 274 MMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPA-PQLPLNAAP-PS 331
+ A+ R +S +++ S S S S + + S+ S S G+ P P++ L P P+
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
Query: 332 SVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVE 391
P E PP P+ R S S +S ++ ++ ++ ++ S
Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-- 2641
Query: 392 DFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPM--VAGFQDDVDLED 449
S +PA+ + K A GE +P + +D L
Sbjct: 2642 --------SSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693
Query: 450 QP--RGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPR 507
P R P P PS SS E +G + +P ET P+ +P
Sbjct: 2694 SPVERRRP----SPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRET-----PSPRPM 2744
Query: 508 R 508
R
Sbjct: 2745 R 2745
Score = 34.7 bits (78), Expect = 0.32
Identities = 103/513 (20%), Positives = 177/513 (34%), Gaps = 106/513 (20%)
Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLN------AAPPSSVPPVPPSEA 341
++ +SPS S+S P G S SSSP T + A + P+ +A P + P ++
Sbjct: 1079 SHSESPSLQSKSQTSPKGGRSR-SSSPVT-ELASRSPIRQDRGEFSASPMLKSGMSPEQS 1136
Query: 342 LPPPACPSAPAPRRSII---SRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDR 398
S P + + SRL T+ + E PP+ A P F DR
Sbjct: 1137 RFQSDSSSYPTVDSNSLLGQSRL-ETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDR 1195
Query: 399 LDRSFL-EDT--TPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRG-- 453
+ S + +DT TP R+ G+ ++ +S AL + + V+ ++P G
Sbjct: 1196 PESSLVFKDTLRTPPRERSGAGSSPETKEQNS---ALPTSSQDEELMEVVEKSEEPAGQI 1252
Query: 454 ------------------SPPLPAGPVPS-------QDITLSSEEEAEVAAPTKGP--AP 486
SP + P S +L + E +A+ GP +P
Sbjct: 1253 LSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSP 1312
Query: 487 APQQCSEPETKWSSIPASKPRRGTAPTRTAAPP-----------WPGGVSVRTGP----- 530
++ S + +S + R + P T P + T P
Sbjct: 1313 EHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMK 1372
Query: 531 --EKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFE-SEGSDTQRRAD 587
RSS +E+ P E+A S + I++ +L V P E S + + D
Sbjct: 1373 EQSTRSSGHSSSELSPDAVEKAGMSSNQ---SISSPVLDAVPRTPSRERSSSASSPEMKD 1429
Query: 588 DFP--------------VRD----------------------DPSDVTDEDEGPAEPPPP 611
P +RD PS E + EP
Sbjct: 1430 GLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKAL 1489
Query: 612 PKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKK 671
P+ P P R + +L L + SE + KT ++ ++ + +E K
Sbjct: 1490 PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV-K 1548
Query: 672 KSKHKKSKDKEEGKEERRRRQQRPPRSRERTAA 704
S + + + + + + + + P R R R+ +
Sbjct: 1549 PSASPQERSESDSSPDSKAKTRTPLRQRSRSGS 1581
Score = 31.2 bits (69), Expect = 3.6
Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 3/83 (3%)
Query: 637 PKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPP 696
P +S EG P E + E A K+ S + KDK++ ++ R P
Sbjct: 296 PSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPE 355
Query: 697 RSR---ERTAADELEAFLGGGAP 716
RS E A L A GG+P
Sbjct: 356 RSSTGPEPPAPTPLLAERHGGSP 378
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 64.7 bits (156), Expect = 3e-10
Identities = 103/459 (22%), Positives = 169/459 (36%), Gaps = 43/459 (9%)
Query: 277 ARSRGHASPLAANGQSPSPGSQSPVVP----AGAVSTGSSSPGTPQPAPQLPLNAAPPSS 332
ARSR A L NG+ G P AGA P P+ +P+ S+
Sbjct: 309 ARSRS-AVTLPRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASA 367
Query: 333 VPPVPPSEALPPPACPSAPAPRRSIISRL-FGTSPATEAAPPPPEPVPAAEGPATVQSVE 391
P P S C APA R + G SPA P PV E + E
Sbjct: 368 SPLTPCSVTRSVHRC--APAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENE 425
Query: 392 DFVPDDRLDRSFLE-DTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQ 450
+RS + + PA ++ A A + S +A +P + +
Sbjct: 426 KEKSALARERSLKKRQSLPASPRARLSASTASELSPKS-KARPSSPSTSWHRPASPCPSP 484
Query: 451 PRG-----SPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASK 505
G PP P G S + +EEA+ + GP Q + S +
Sbjct: 485 GPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPAS 544
Query: 506 PRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQM 565
P AP+ T APP T + T PPA P + + +D E A ++
Sbjct: 545 PAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREE--ATRL 602
Query: 566 LSFVMDDPDFESEGSDTQRRAD---DFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLK 622
L+ + E + +RR D +R++ + E E AE
Sbjct: 603 LAEKRRQAREQREREEQERRLQAERDKRMREE--QLAREAEARAE--------------- 645
Query: 623 NDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKE 682
+++ +EA K +E+ +E + K+K++ + + +EE E+ ++ KH + +++E
Sbjct: 646 REAEARRREEQEAREKAQAEQ-EEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQE 704
Query: 683 EGKEERR-----RRQQRPPRSRERTAADELEAFLGGGAP 716
+ +R +R ++ S + D EA G +P
Sbjct: 705 RQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSP 743
Score = 42.0 bits (97), Expect = 0.002
Identities = 35/109 (32%), Positives = 44/109 (40%), Gaps = 12/109 (11%)
Query: 293 PSP-GSQSPVVPAGAVSTGSSSPGTPQP------APQLPLNAAPPSSVPPVPPSEALPPP 345
PSP G SP P + + P TP + QLPL PS V P A P
Sbjct: 27 PSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSG--QVGPRPAPPQE 84
Query: 346 ACPSAPAPRRSIISRLFG---TSPATEAAPPPPEPVPAAEGPATVQSVE 391
PS+ A R G P ++ P P VPA++ P T Q V+
Sbjct: 85 ESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVK 133
Score = 41.2 bits (95), Expect = 0.003
Identities = 55/199 (27%), Positives = 78/199 (39%), Gaps = 27/199 (13%)
Query: 521 PGGVSVRTGPEKRSSTR-----PPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDF 575
P V RT PE R S PP M A ++ P+ P A + + P
Sbjct: 14 PPAVVARTPPEPRPSPEGDPSPPPPPMS------ALVPDTPPDTPPAMKNATSSKQLP-L 66
Query: 576 ESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEA 635
E E Q P +++ + GP P P+ P R S A
Sbjct: 67 EPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPS-------PTA 119
Query: 636 GPKESSEEGKEGKTPSKEKKKKKKKGKEEEEK--AAKKK---SKHKKSKD-KEEGKEERR 689
P S K+ + E+ K K+ +EE K AAKK K +K+K +E+ +ERR
Sbjct: 120 VPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERR 179
Query: 690 RR--QQRPPRSRERTAADE 706
RR +QR + R A +E
Sbjct: 180 RRLEEQRLKAEQRRAALEE 198
Score = 38.5 bits (88), Expect = 0.022
Identities = 58/257 (22%), Positives = 87/257 (33%), Gaps = 43/257 (16%)
Query: 447 LEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKP 506
+E PR L AG P+ + + E P P P P+T + PA K
Sbjct: 1 MESGPRAE--LGAGAPPAV-VARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMK- 56
Query: 507 RRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQML 566
A + P P S + GP PP E P SSE+ GP M
Sbjct: 57 ---NATSSKQLPLEPESPSGQVGPRPA----PPQEESP-------SSEAKSRGPTPPAMG 102
Query: 567 SFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSD 626
P S+ S T PA PP K +K +
Sbjct: 103 PRDARPPRRSSQPSPTAV--------------------PASDSPPTKQ-----EVKKAGE 137
Query: 627 LFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKE 686
L E + K+ KE+K K + K+ +E+ + + + K++ + E
Sbjct: 138 RHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALE 197
Query: 687 ERRRRQQRPPRSRERTA 703
ER+R++ + R A
Sbjct: 198 ERQRQKLEKNKERYEAA 214
Score = 34.3 bits (77), Expect = 0.42
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 14/77 (18%)
Query: 313 SPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR----LFGTSPAT 368
+P P+P+P+ PS PP PP AL P P P ++ S L SP+
Sbjct: 21 TPPEPRPSPE-----GDPS--PPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSG 73
Query: 369 EAAP---PPPEPVPAAE 382
+ P PP E P++E
Sbjct: 74 QVGPRPAPPQEESPSSE 90
Score = 32.3 bits (72), Expect = 1.6
Identities = 36/157 (22%), Positives = 56/157 (35%), Gaps = 28/157 (17%)
Query: 318 QPAPQLPLNA-APPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPE 376
+ P+ L A APP+ V PP P PS P P S + PP+
Sbjct: 2 ESGPRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSAL-----------VPDTPPD 50
Query: 377 PVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNP 436
PA + + + + LE +P+ A ++ S+ ++ G P
Sbjct: 51 TPPAMKNATSSKQLP------------LEPESPSGQVGPRPAPPQEESPSSEAKSRGPTP 98
Query: 437 MVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEE 473
G + D R S P P VP+ D + +E
Sbjct: 99 PAMGPR---DARPPRRSSQPSPTA-VPASDSPPTKQE 131
Score = 31.2 bits (69), Expect = 3.6
Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 17/112 (15%)
Query: 233 QLQRETLLRQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQS 292
+L+RE +Q E + + LEE+ + E+ E + + + ANG S
Sbjct: 691 RLEREKHFQQQEQERQERRKRLEEIMKRTRKS--------EVSETKQKQDSKEANANGSS 742
Query: 293 PSP----GSQSPVVPAGAVSTGSSSPGTPQ---PAPQLPLNAAPPSSVPPVP 337
P P ++SP + AV P PQ P+ +LP A+ + + P+P
Sbjct: 743 PEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELP--ASLVNGLQPLP 792
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 63.9 bits (154), Expect = 5e-10
Identities = 73/295 (24%), Positives = 103/295 (34%), Gaps = 48/295 (16%)
Query: 293 PSPGSQSPVVPAGAVSTGS---------SSPGTPQPAPQLPLNAAPPSSVPPVPPSEALP 343
PSP + P+ P S + +P +P P+P + +PP+S PPV PS P
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSATPP 467
Query: 344 PPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSF 403
A PS AP + + P + +A PPP+ P P
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP------------------ 509
Query: 404 LEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPV- 462
L+ P A Q S + G A F L P +PP A PV
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPSPPASFPGQ---APFSPSASLPMSPLATPPPQAPPVL 566
Query: 463 --PSQDITLSSEEEAEVAAPTKGPAPAPQ-QCSEPETKWSSIPASKPRRGTAPTRTAAPP 519
P + S + AP + P P P S P + P P +P+ T + P
Sbjct: 567 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626
Query: 520 WPGGVS------------VRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIA 562
G S +GPE ++ PP + E A+ S P P+A
Sbjct: 627 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG-PAPPLA 680
Score = 56.2 bits (134), Expect = 1e-07
Identities = 84/289 (29%), Positives = 105/289 (36%), Gaps = 42/289 (14%)
Query: 283 ASPLAANGQSPSPGSQS-PVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPS-E 340
+SPLA S + SQ+ P +PA T SS T Q A LPL APPS P PPS +
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPA----TPHSSSLTCQLATPLPL--APPS--PSAPPSLQ 352
Query: 341 ALP-PPACPSAPA------PRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDF 393
LP PPA P + A P + P + A PPP+ PA P
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL------- 405
Query: 394 VPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRG 453
P S AL + + A F Q
Sbjct: 406 -------------QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452
Query: 454 SPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPT 513
SP PA P S T S+ +AAP P+P S P + ++ P P AP
Sbjct: 453 SP--PASPPVSPSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPP 509
Query: 514 RTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIA 562
A P P P ++ PPA PG+ S S S P P+A
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPSPPASF-PGQA-PFSPSASLPMSPLA 556
Score = 38.9 bits (89), Expect = 0.017
Identities = 76/337 (22%), Positives = 102/337 (30%), Gaps = 73/337 (21%)
Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342
A A G++ +S + T +PGTP PA AA P P A
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
Query: 343 PPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRS 402
P P PR+S+ S A+E + P P A P+ ++ RS
Sbjct: 198 PR---PPTEGPRKSV-------SSASEHSTTEPSPA-ARRRPSAGGGLQ-----RPASRS 241
Query: 403 FLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPV 462
TP + G A RG+P PA P
Sbjct: 242 LSSSATPLSSPARSGPSA-------------------------------RGTPRAPAHPS 270
Query: 463 PSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPG 522
+ L + +V P K APA SS P + P A A P P
Sbjct: 271 QPKPKGLQALRPPQVTPPRKDAAPALGPL-------SSSPLATPSPSAALQSQAPPTLPA 323
Query: 523 GVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDT 582
+ + ++ P A P + S P P + S GS T
Sbjct: 324 TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL----------GSPT 373
Query: 583 QRRADDFPVRDDPSDVTDEDEGPAEPPP--PPKLPLP 617
+ F S + A PPP PP L LP
Sbjct: 374 LQATHSFLPSPPLSPL-------ATPPPQAPPALALP 403
Score = 34.7 bits (78), Expect = 0.32
Identities = 81/325 (24%), Positives = 99/325 (30%), Gaps = 80/325 (24%)
Query: 320 APQLPLNAAPPSSVPPVPPSEALPPPACPSA--------PAPRRSIISRLFGTSPATEAA 371
A + P AP P P S PPP P+A R+ + R G AT
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT--- 69
Query: 372 PPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEA 431
PE P A GP P R PA G +A + S G
Sbjct: 70 --IPESAPRA-GPTRSAGTSSRNPASR---------PPASGR---GERAPPAKNTSPG-- 112
Query: 432 LGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGP------A 485
+ R S GP+ + + +S+EE T+ P A
Sbjct: 113 --------------PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA 158
Query: 486 PAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPG 545
A + S P T + PA R A T P R P R RPP E P
Sbjct: 159 GARRDTSGP-TPGTPSPAMARRSRAAGTEVGLP--------RPAPSAR--PRPPTE-GPR 206
Query: 546 KGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRAD----------DFPVRDDP 595
K ++S S E AA+ S G QR A P R P
Sbjct: 207 KSVSSASEHSTTEPSPAARRR---------PSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 596 SDVTDEDEGPAEPPPPPKLPLPAFR 620
S PA P P L A R
Sbjct: 258 S-ARGTPRAPAHPSQPKPKGLQALR 281
Score = 31.6 bits (70), Expect = 2.7
Identities = 28/107 (26%), Positives = 34/107 (31%), Gaps = 15/107 (14%)
Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE----ALP 343
A G P P +G G SS T P ++ P PP + A
Sbjct: 608 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667
Query: 344 PPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSV 390
P A PAP A AP P P P A GP + +
Sbjct: 668 PAAWSRGPAP-----------PLAFRGAPGAPLPWPPATGPGSADGL 703
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 63.9 bits (154), Expect = 5e-10
Identities = 73/295 (24%), Positives = 103/295 (34%), Gaps = 48/295 (16%)
Query: 293 PSPGSQSPVVPAGAVSTGS---------SSPGTPQPAPQLPLNAAPPSSVPPVPPSEALP 343
PSP + P+ P S + +P +P P+P + +PP+S PPV PS P
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSATPP 428
Query: 344 PPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSF 403
A PS AP + + P + +A PPP+ P P
Sbjct: 429 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP------------------ 470
Query: 404 LEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPV- 462
L+ P A Q S + G A F L P +PP A PV
Sbjct: 471 LQLAKPPPQAPPALATPPLQALPSPPASFPGQ---APFSPSASLPMSPLATPPPQAPPVL 527
Query: 463 --PSQDITLSSEEEAEVAAPTKGPAPAPQ-QCSEPETKWSSIPASKPRRGTAPTRTAAPP 519
P + S + AP + P P P S P + P P +P+ T + P
Sbjct: 528 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 587
Query: 520 WPGGVS------------VRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIA 562
G S +GPE ++ PP + E A+ S P P+A
Sbjct: 588 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG-PAPPLA 641
Score = 50.1 bits (118), Expect = 7e-06
Identities = 74/289 (25%), Positives = 99/289 (34%), Gaps = 30/289 (10%)
Query: 278 RSRGHASPLAANG-QSPSPGSQSPVVPAGAVSTG--SSSPGTPQPAPQLPLNAAPPSSVP 334
R+ H S G Q+ P +P A + G SSSP P+P P + + P S+
Sbjct: 255 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-LATPSPSAPPSPSAPPSLQ 313
Query: 335 PVPPSEALPPP-ACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDF 393
+P A PP A S +P + P + A PPP+ PA P
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL------- 366
Query: 394 VPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRG 453
P S AL + + A F Q
Sbjct: 367 -------------QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413
Query: 454 SPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPT 513
SP PA P S T S+ +AAP P+P S P + ++ P P AP
Sbjct: 414 SP--PASPPVSPSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPP 470
Query: 514 RTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIA 562
A P P P ++ PPA PG+ S S S P P+A
Sbjct: 471 LQLAKPPPQAPPALATPPLQALPSPPASF-PGQA-PFSPSASLPMSPLA 517
Score = 42.0 bits (97), Expect = 0.002
Identities = 76/349 (21%), Positives = 111/349 (31%), Gaps = 33/349 (9%)
Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342
+SPLA S P +P ++ T S P TP L + + PS L
Sbjct: 292 SSPLATPSPSAPPSPSAPP----SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 347
Query: 343 PPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRS 402
P A P AP + P +A P PP P + + + L
Sbjct: 348 SPLATPPPQAPPALAL-------PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400
Query: 403 FLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPL-PAGP 461
F +P + A+ S S P +A + + P SPP+ P+
Sbjct: 401 FSPPPSPP-VQAPFSPPASPPVSPSATPPSQAPPSLAA--PPLQVPPSPPASPPMSPSAT 457
Query: 462 VPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRR------GTAPTRT 515
P Q + ++A P P P + P S PAS P + + P
Sbjct: 458 PPPQAPPPLAAPPLQLAKPP--PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 515
Query: 516 AAPPWPGGVSVRTGPEKRSSTRPPAE--MEPGKGEQASSSESDPEGPIAAQMLSFVMDDP 573
A P P V P + PPA ++ + ++ GP L+ P
Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575
Query: 574 DFESEG---SDTQRRADDFPVRDDPSDVTDEDEGP-----AEPPPPPKL 614
S S P ++ D GP A PPP +L
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 624
Score = 41.2 bits (95), Expect = 0.003
Identities = 55/242 (22%), Positives = 76/242 (31%), Gaps = 52/242 (21%)
Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342
A A G++ +S + T +PGTP PA AA P P A
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188
Query: 343 PPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRS 402
P P PR+S+ S A+E + P P A P+ ++ RS
Sbjct: 189 PR---PPTEGPRKSV-------SSASEHSTTEPSPA-ARRRPSAGGGLQ-----RPASRS 232
Query: 403 FLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPV 462
TP + G A RG+P PA P
Sbjct: 233 LSSSATPLSSPARSGPSA-------------------------------RGTPRAPAHPS 261
Query: 463 PSQDITLSSEEEAEVAAPTKGPAPA-----PQQCSEPETKWSSIPASKPRRGTAPTRTAA 517
+ L + +V P K APA + P P++ P T P+ A
Sbjct: 262 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT 321
Query: 518 PP 519
PP
Sbjct: 322 PP 323
Score = 37.0 bits (84), Expect = 0.065
Identities = 70/314 (22%), Positives = 99/314 (31%), Gaps = 34/314 (10%)
Query: 320 APQLPLNAAPPSSVPPVPPSEALPPPACPSA--------PAPRRSIISRLFGTSPAT--- 368
A + P AP P P S PPP P+A R+ + R G AT
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
Query: 369 ---EAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDS 425
A P PA+ ++ P TT + G + + +++
Sbjct: 73 SAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 132
Query: 426 DSDG---EALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTK 482
+ G EA + + AG + D S P P P P+ S EV P
Sbjct: 133 VARGKATEAPKRSALSAGARRDT--------SGPTPGTPSPAM-ARRSRAAGTEVGLPRP 183
Query: 483 GPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTA-APPWPGGVSVRTGPEKRSSTRPPAE 541
P+ P+ +E K S+ ++ T P+ A P GG R SS+ P
Sbjct: 184 APSARPRPPTEGPRK--SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241
Query: 542 MEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDE 601
G A + P P + P T R D P S
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPP-----QVTPPRKDAAPALGPLSSSPLA 296
Query: 602 DEGPAEPPPPPKLP 615
P+ PP P P
Sbjct: 297 TPSPSAPPSPSAPP 310
Score = 34.3 bits (77), Expect = 0.42
Identities = 54/234 (23%), Positives = 83/234 (35%), Gaps = 48/234 (20%)
Query: 447 LEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKP 506
L +P GSP P P+ L AA G P ++ ++IP S P
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLG-------AAGAVGRKPLAERAGG--IGGATIPESAP 75
Query: 507 RRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQML 566
R G PTRT+ RPPA G+GE+A +++ GP+++
Sbjct: 76 RAG--PTRTS--------------------RPPAS---GRGERAPPAKNTSPGPVSSPGR 110
Query: 567 SFVMDDPD--------FESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPA 618
+ P +E + + +A + P R S D P P P PA
Sbjct: 111 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS----GPTPGTPSPA 166
Query: 619 FRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKK 672
++ + +GL P EG P K + E AA+++
Sbjct: 167 MARRSRAAGTEVGLPRPAPSARPRPPTEG--PRKSVSSASEHSTTEPSPAARRR 218
Score = 31.6 bits (70), Expect = 2.7
Identities = 28/107 (26%), Positives = 34/107 (31%), Gaps = 15/107 (14%)
Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE----ALP 343
A G P P +G G SS T P ++ P PP + A
Sbjct: 569 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628
Query: 344 PPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSV 390
P A PAP A AP P P P A GP + +
Sbjct: 629 PAAWSRGPAP-----------PLAFRGAPGAPLPWPPATGPGSADGL 664
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 63.9 bits (154), Expect = 5e-10
Identities = 86/363 (23%), Positives = 127/363 (34%), Gaps = 75/363 (20%)
Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALP-------PP 345
P P P P + T + T AP + AAPP+ PPVPP++ P PP
Sbjct: 768 PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVT-QAAPPTPTPPVPPAKKQPAFPASYIPP 826
Query: 346 ACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLE 405
+ P+ P P T P ++ P P P + P+ V+ + P
Sbjct: 827 SPPTPPVPVPP------PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP-------- 872
Query: 406 DTTPARDE---KKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPV 462
T PA + K V A A Q + ++ +P+ P + PV
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPA-------------------VKAKPKWQPS--SIPV 911
Query: 463 PSQDITLSSEEEAEV-----AAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAA 517
PS D E + V +P P P P + P S P K + ++P
Sbjct: 912 PSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP 971
Query: 518 PPWP---GGVSVRTGPEKRSSTRPPAEMEPGK-------GEQASSSESDPEGP------- 560
PP P + +G E RP + K G + + P P
Sbjct: 972 PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLN 1031
Query: 561 IAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPK--LPLPA 618
++ L V+ ++ R D V + PS +D D PPPPP+ LPLP
Sbjct: 1032 LSGVNLPGVLQQGCVSAKAPVLSGRGKDSVV-EFPSPPSDSDF----PPPPPETELPLPP 1086
Query: 619 FRL 621
+
Sbjct: 1087 IEI 1089
Score = 55.5 bits (132), Expect = 2e-07
Identities = 93/429 (21%), Positives = 139/429 (32%), Gaps = 96/429 (22%)
Query: 314 PGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPP 373
P +PQP P A+ PS PP+PP PPP P P P PP
Sbjct: 608 PLSPQPKIVTPYTASQPS--PPLPPP---PPPPPPPPPPP------------------PP 644
Query: 374 PPEPVPAAEGPATVQSVEDFVPDDRLDR----------SFLEDTTPARDEKKVGAKAAQQ 423
PP P+P+ P+ + FV + R F T P + V +
Sbjct: 645 PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP 704
Query: 424 DSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEE-AEVAAPT- 481
+ P L+ P +P LP P + + + +VA PT
Sbjct: 705 PNGVVPPPPPPPPPPTPGSAMAQLKPAP-CAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763
Query: 482 --KGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRT-AAPPWPGGVSVRTGPEKRSSTRP 538
P PAP P +IPA + AP T AAPP P + P K+ P
Sbjct: 764 PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP---TPPVPPAKKQPAFP 820
Query: 539 PAEMEPGK------------GEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRA 586
+ + P +Q S P P++ + V+ + T
Sbjct: 821 ASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP--VPSVVKQIASQFPPPPTPPAM 878
Query: 587 DDFPVRDDPSDVTDE---------------------DEGPAEP------PPPPKLPLPAF 619
+ P++ P++V + D P P PPPP P+PA
Sbjct: 879 ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA- 937
Query: 620 RLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSK 679
P +S + +P K+ K G ++ ++ S K S
Sbjct: 938 ------------PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS 985
Query: 680 DKEEGKEER 688
E + +R
Sbjct: 986 GAEHPEPKR 994
Score = 48.9 bits (115), Expect = 2e-05
Identities = 82/356 (23%), Positives = 119/356 (33%), Gaps = 57/356 (16%)
Query: 285 PLAAN--GQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSV---PPVPPS 339
P+ AN QSP P ++ S P P L PPS V PP PP
Sbjct: 885 PVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPP 944
Query: 340 EALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPE-----------PVPAAEGPATVQ 388
A P P +P + S S SP + PP P+ P + P+
Sbjct: 945 TASPTPDKSGSPGKKTSKTS-----SPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDS 999
Query: 389 SVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGG-----NPMVAGFQD 443
V F P E P K G K + G G P+++G
Sbjct: 1000 LVSKFTPPAESGSPSKETLPPPAAPPKPG-KLNLSGVNLPGVLQQGCVSAKAPVLSGRGK 1058
Query: 444 D--VDLEDQPRGS---PPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKW 498
D V+ P S PP P +P I + + + P PQQ S+ K
Sbjct: 1059 DSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVK- 1117
Query: 499 SSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPE 558
+ P ++P+R + T A P+ +S + ++PG
Sbjct: 1118 KAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPG------------- 1164
Query: 559 GPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKL 614
L+ + GS + R + R +P+ D+ A PPPPP+L
Sbjct: 1165 ---FLADLNRTLQRKSITRHGSLSSRMS-----RAEPTATMDD---MALPPPPPEL 1209
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/376 (23%), Positives = 115/376 (30%), Gaps = 77/376 (20%)
Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350
QS S Q V P G V P P P P P +A + + P P + +LP + P
Sbjct: 693 QSQSVKPQILVPPNGVVP-----PPPPPPPPPTPGSAM--AQLKPAPCAPSLPQFSAPPP 745
Query: 351 PAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPA 410
P ++ T+ APP P P P P Q+ P L T PA
Sbjct: 746 PL-------KIHQVQHITQVAPPTPPPPPPIPAPLPPQA-----PPKPL------VTIPA 787
Query: 411 RDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLS 470
K A Q + P+ + SPP P PVP TL
Sbjct: 788 PTSTKTVAPVVTQAAPPTPTP----PVPPAKKQPAFPASYIPPSPPTPPVPVPPP--TLP 841
Query: 471 SEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGP 530
++ P +P P + I + P T P + P P V P
Sbjct: 842 KQQSFCAKPPPSPLSPVPSVVKQ-------IASQFPPPPTPPAMESQPLKP--VPANVAP 892
Query: 531 EKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFP 590
+ PPA K + +S P+ P S V P
Sbjct: 893 QS-----PPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP----------------- 930
Query: 591 VRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTP 650
PS V PA PPPPP P D G ++ S K TP
Sbjct: 931 ---PPSPV------PAPPPPPPPTASPT------PDKSGSPGKKTSKTSSPGGKKPPPTP 975
Query: 651 SKEKKKKKKKGKEEEE 666
+ K G E E
Sbjct: 976 QRNSSIKSSSGAEHPE 991
Score = 47.4 bits (111), Expect = 5e-05
Identities = 97/399 (24%), Positives = 132/399 (33%), Gaps = 70/399 (17%)
Query: 285 PLAANGQSPSPGSQSPVVP----------AGAVSTGSSSPGTP--------QPAPQLPLN 326
P + +PS GS +P+ A S P TP +P +P N
Sbjct: 647 PPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPN 706
Query: 327 AAPPSSVPPVPP-------SEALPPPACPS-----APAPRRSIISRLFGTSPATEAAPPP 374
P PP PP ++ P P PS AP P I T A PPP
Sbjct: 707 GVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPT-PPP 765
Query: 375 PEPVPAAEGPATVQSVEDFVPDDRLDRSFL---------EDTTPARDEKKVGAKAAQQDS 425
P P+PA P +P ++ T P KK A A
Sbjct: 766 PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP 825
Query: 426 DSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSE------EEAEVAA 479
S P+ + PP P PVPS ++S+ A +
Sbjct: 826 PSPPTP----PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ 881
Query: 480 PTKGPAPA-------PQQCSEPETKWSSIPASKPRRGTAPTRTA---APPWPGGV-SVRT 528
P K P PA P ++P+ + SSIP P P ++ PP P V +
Sbjct: 882 PLK-PVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940
Query: 529 GPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADD 588
P +S P PGK +SS + P Q S + +E + +R + D
Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG--AEHPEPKRPSVD 998
Query: 589 ------FPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRL 621
P + S + PA PP P KL L L
Sbjct: 999 SLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNL 1037
Score = 39.7 bits (91), Expect = 0.010
Identities = 39/139 (28%), Positives = 53/139 (38%), Gaps = 39/139 (28%)
Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLP-LNAAPPSSVPPV----PP 338
SP ++ SPG + P S+ SS G P P+ P +++ PP P
Sbjct: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPS 1014
Query: 339 SEALPPPA----------------------CPSAPAP------RRSIISRLFGTSPATEA 370
E LPPPA C SA AP + S++ F + P+
Sbjct: 1015 KETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVE--FPSPPSDSD 1072
Query: 371 APPPPE----PVPAAEGPA 385
PPPP P+P E PA
Sbjct: 1073 FPPPPPETELPLPPIEIPA 1091
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 63.9 bits (154), Expect = 5e-10
Identities = 96/349 (27%), Positives = 137/349 (39%), Gaps = 37/349 (10%)
Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342
ASP + +P+P S + PA + S ++P P APQ + A PS PP+ P L
Sbjct: 1556 ASPFPS-APNPAPAQASLLAPASSASQALATPLAPMAAPQTAILA--PSPAPPLAPLPVL 1612
Query: 343 PP-----PACPSAPAPRRSII-SRLFGTSPATEAAPPPPEPVPAAEGPATV--QSVEDFV 394
P P S+ P + S GTS A+ + P P PV A T+ V +
Sbjct: 1613 APSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPL 1672
Query: 395 PDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNP-MVAGFQDDVDLEDQPRG 453
P ++ PA G+ +Q S G G P L P
Sbjct: 1673 PSPASTQTLA--LAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQ 1730
Query: 454 SPPLPAGPV--PSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSI--PASKPRRG 509
+ L GP P+Q ++L+ A+P GPAPA P + +S+ PAS
Sbjct: 1731 TLSLAPGPPLGPTQTLSLAPAPPLAPASPV-GPAPAHTLTLAPASSSASLLAPASVQTLT 1789
Query: 510 TAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFV 569
+P A P G + +T +ST+ PA AS + P ++ +S
Sbjct: 1790 LSP---APVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVS-- 1844
Query: 570 MDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGP---AEPPPPPKLP 615
D+PD + T R P PS T GP +PPPPP+ P
Sbjct: 1845 KDEPD-----TLTLRSGPPSP----PSTATSFG-GPRPRRQPPPPPRSP 1883
Score = 61.6 bits (148), Expect = 2e-09
Identities = 75/300 (25%), Positives = 109/300 (36%), Gaps = 39/300 (13%)
Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344
P++ P+P S +P A T S+S P L + PP + PV P+ PP
Sbjct: 1440 PISVPTTLPAPASAPLTIPISAPLTVSAS------GPALLTSVTPP--LAPVVPAAPGPP 1491
Query: 345 PACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVED---------FVP 395
PS +P S ++ T+P+ ++ P P+ A + V + VP
Sbjct: 1492 SLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVP 1551
Query: 396 DDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSP 455
L F PA + + A A+ S S A PM A Q
Sbjct: 1552 ASALASPFPSAPNPAPAQASLLAPAS---SASQALATPLAPMAA---------PQTAILA 1599
Query: 456 PLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSS---IPASKPRRGTAP 512
P PA P+ + S A V A ++ P P S P T +S +PA P +
Sbjct: 1600 PSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSS 1659
Query: 513 TRTAAP-----PWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLS 567
T+T P P P S +T + P + S +P+GP Q LS
Sbjct: 1660 TQTMLPAPVPSPLPSPASTQT--LALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLS 1717
Score = 48.1 bits (113), Expect = 3e-05
Identities = 79/305 (25%), Positives = 105/305 (34%), Gaps = 62/305 (20%)
Query: 285 PLAANGQSPSPG------SQSPVVPAGAVSTGSSSPG---TPQPAPQLPLNAAPPSSVPP 335
PL SPSP +P+ + + SS PG +P P P A+P SS
Sbjct: 1373 PLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVS 1432
Query: 336 VPPSEALPPPACPSAPAPRRSIIS-------RLFGTSPA--TEAAPPPPEPVPAAEGPAT 386
VP S +LP + PAP + ++ + + PA T PP VPAA GP +
Sbjct: 1433 VPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPS 1492
Query: 387 VQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQ--QDSDSDGEAL----------GG 434
+ +P+ +G A S + G L G
Sbjct: 1493 LAP---------------SGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGL 1537
Query: 435 NPMVAGFQDDVDLEDQPRGSP-PLPAGPVPSQDITLSSEEEAEVAAPTK-GPAPAPQQCS 492
N VA V + SP P P P+Q L+ A A T P APQ
Sbjct: 1538 NSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQ--- 1594
Query: 493 EPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASS 552
++I A P AP AP PG P SS P M P S
Sbjct: 1595 ------TAILAPSPAPPLAPLPVLAPS-PG-----AAPVLASSQTPVPVMAPSSTPGTSL 1642
Query: 553 SESDP 557
+ + P
Sbjct: 1643 ASASP 1647
Score = 44.7 bits (104), Expect = 3e-04
Identities = 101/469 (21%), Positives = 161/469 (34%), Gaps = 85/469 (18%)
Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSP---GTPQPAPQLPLNAAP----PSSVPPVP 337
P A P+P S +PA V S+P P P LP++ P PS +PP
Sbjct: 2437 PRPAPRPRPTPASAPAAIPA-LVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCS 2495
Query: 338 PSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPA----------------A 381
PPPAC PA T + PP P+ A A
Sbjct: 2496 SPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCA 2555
Query: 382 EGPATVQSVE------------DFVPDDRLDRSFLE---------DTTPARDE--KKVGA 418
+ A+ +S+E VP L +E TP+ + G+
Sbjct: 2556 QALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGS 2615
Query: 419 KAAQQDSDSDGEALGGNPMVAGFQDDVDL---EDQPRGSPPLPAGPVPSQDITLSSEEEA 475
Q+ ++ A G V +++ L E PP A P Q+ L ++ +
Sbjct: 2616 IPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQE-PLEADRTS 2674
Query: 476 EVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSS 535
E K P +P++ E T + P+ T ++A P G S P +R+S
Sbjct: 2675 EELTEAKTPTSSPEKPQELVTAEVAAPS---------TSSSATSSPEGPSPARPPRRRTS 2725
Query: 536 TRPPAEMEPGKGEQASSSESDPEGPIAAQMLS----FVMDDPDF-----ESEG------- 579
A++E +G Q + P GP + L V+++ + + G
Sbjct: 2726 ----ADVEI-RG-QGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVP 2779
Query: 580 --SDTQRRADDFPVRD-DPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAG 636
S+T VR + + GP E P LP P + LG+ G
Sbjct: 2780 GVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGG 2839
Query: 637 PKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGK 685
E+ + TP K+++ + K+ A + + +GK
Sbjct: 2840 SPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGK 2888
Score = 43.9 bits (102), Expect = 5e-04
Identities = 76/345 (22%), Positives = 125/345 (36%), Gaps = 65/345 (18%)
Query: 359 SRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGA 418
S G+S A + PPP + +G DF P + + DE+ +
Sbjct: 263 SPCLGSSSAASSPPPPASRLDDEDG--------DFQPQEDEEED---------DEETI-- 303
Query: 419 KAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPP-LPAGPV-PSQDITLSSEEEAE 476
+ +Q +D EA + + ++ LE+ R PP L GP PSQ T SS +
Sbjct: 304 EVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLLEGPSSPSQ--TPSSHDSDT 361
Query: 477 VAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSST 536
P +G P Q E + S++ T+ PW P++
Sbjct: 362 RDGPEEGAEEEPPQVLEIKPPPSAV-----------TQRNKQPWH--------PDEDDEE 402
Query: 537 RPPAEMEPGKGEQASSSESDPEGPIAAQM-LSFVMDDPDFESEGSDTQRRADDFPVRDDP 595
E E E ++E EG + M LS + + + E Q+ A +
Sbjct: 403 FTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEEL-LQQYAGAYAPGSGS 461
Query: 596 SDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKK 655
S+ DEDE A N SD E GP E+ E +E + +
Sbjct: 462 SEDEDEDEVDA----------------NSSDC-----EPEGPVEAEEPPQEDSSSQSDSV 500
Query: 656 KKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRE 700
+ + + +E+E ++ S S++ E + E + Q + E
Sbjct: 501 EDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEE 545
Score = 42.4 bits (98), Expect = 0.002
Identities = 104/450 (23%), Positives = 160/450 (35%), Gaps = 85/450 (18%)
Query: 296 GSQSPVVPAGAVSTGSSSPGTP--------QPAPQL--PLNAAPPSSVPPVPPSEALP-- 343
G+ S +VP VS S+SPG+P + +P + P AAP SS+P P +
Sbjct: 2772 GAASTLVPG--VSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARR 2829
Query: 344 --PPACPSAPAPRRSIISRLFGTSPATE---AAPPPPEPVPAAEGPATVQSVEDFVPDDR 398
+P + L T PA + PP PA G + V++
Sbjct: 2830 HIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAG----RGVDEAPSSTL 2885
Query: 399 LDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLP 458
++ D P + V + + LG P+ +E + RG PP
Sbjct: 2886 KGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKA 2945
Query: 459 AG-PVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAA 517
P+P T+SS + + T+ P P P + P PT T A
Sbjct: 2946 RDLPIPG---TISSAGDGNSESRTQ-PPPHPSPLT-----------PLPPLLVCPTATVA 2990
Query: 518 PPWPGGVSVRTGPEKRSSTRPP-----------------------------AEMEPGKGE 548
V++ T P KR RPP G+GE
Sbjct: 2991 NT-VTTVTISTSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGE 3049
Query: 549 QASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVR--DDPSDVTDEDEGPA 606
SS SD +G L+ + E+EG ++ V D D+ D G
Sbjct: 3050 SEGSS-SDEDGSRPLTRLARLR----LEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGL 3104
Query: 607 EPPPP-----PKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKG 661
E PP PK L + RL+ S + L E+ K + G +P K+ + +
Sbjct: 3105 ELTPPVVSLTPK--LRSTRLRPGSLVPPLETEKLPRKRAG--APVGGSPGLAKRGRLQPP 3160
Query: 662 KEEEEKAAKKKSKHKKSKDKEEGKEERRRR 691
+ + ++S+ + S ++EEG RRR
Sbjct: 3161 SPLGPEGSVEESEAEASGEEEEGDGTPRRR 3190
Score = 39.3 bits (90), Expect = 0.013
Identities = 47/196 (23%), Positives = 77/196 (39%), Gaps = 42/196 (21%)
Query: 221 KYLHKFFNIPFLQLQRETLLR---QLETNQLDMDATLEELSVQQETEDQNYGIFLEMM-- 275
+Y KF ++ RE L + Q+E + D+D EE+ + E++ G E
Sbjct: 2314 RYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDESSCG 2373
Query: 276 -----EARSRGHASP----------LAANGQSPSPGSQSPVVPAGAVSTGSSSPG----- 315
RS+ +P L + +PV+ A + ++ P
Sbjct: 2374 TGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPAR 2433
Query: 316 --TPQPAPQ-LPLNAAPPSSVP---PVPPSEALPPPACPSAPAPRRSIISRLFGTSPATE 369
P+PAP+ P A+ P+++P PVP S +P SAP P + +
Sbjct: 2434 ERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPI----SAPNPITILPVHIL------- 2482
Query: 370 AAPPPPEPVPAAEGPA 385
+PPPP +P PA
Sbjct: 2483 PSPPPPSQIPPCSSPA 2498
Score = 38.1 bits (87), Expect = 0.029
Identities = 32/95 (33%), Positives = 41/95 (43%), Gaps = 13/95 (13%)
Query: 293 PSPGSQSPVVPAG-AVSTGSSSPGTP----QPAPQLPLN---AAPPSSVPPVPPSEALPP 344
P+ GS V+P+ V +G+S P TP +P P P+ A PP S + P P
Sbjct: 1077 PNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPG 1136
Query: 345 PACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVP 379
P A A S T+ AT A P P P P
Sbjct: 1137 YTFPPAAATTTSTT-----TATATTTAVPAPTPAP 1166
Score = 37.0 bits (84), Expect = 0.065
Identities = 74/323 (22%), Positives = 108/323 (33%), Gaps = 86/323 (26%)
Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGS-SSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342
SP+ + P ++ +P S G +S QP P PS + P+PP
Sbjct: 2932 SPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPH-------PSPLTPLPPLLV- 2983
Query: 343 PPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRS 402
CP+A ++ + TSP PP+ P+ P+ + + DR S
Sbjct: 2984 ----CPTATVAN-TVTTVTISTSPPKRKRGRPPKNPPSPR-PSQLPVL------DRDSTS 3031
Query: 403 FLEDTTPARDEKKVGAKAAQ-QDSDSDGEA-------------------LGGNPMVAGFQ 442
LE R + G ++ SD DG GG+ +VA Q
Sbjct: 3032 VLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQ 3091
Query: 443 DDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIP 502
DD+DL D G L PV S P+ S S +P
Sbjct: 3092 DDLDLADSGPGGLEL-TPPVVSL---------------------TPKLRSTRLRPGSLVP 3129
Query: 503 ASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIA 562
+ + P + A P G G KR +PP+ + P + S +E+ E
Sbjct: 3130 PLETEK--LPRKRAGAPVGGS----PGLAKRGRLQPPSPLGPEGSVEESEAEASGE---- 3179
Query: 563 AQMLSFVMDDPDFESEGSDTQRR 585
E EG T RR
Sbjct: 3180 -------------EEEGDGTPRR 3189
Score = 34.7 bits (78), Expect = 0.32
Identities = 53/255 (20%), Positives = 94/255 (36%), Gaps = 47/255 (18%)
Query: 489 QQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGE 548
Q ++P T SS S P G++ ++ PP + G + P E E E
Sbjct: 249 QSLNQPLT--SSKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQ------PQEDEEEDDE 300
Query: 549 QASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDED-EGPAE 607
+ E EG +D + + + RR + P+ + + + EGP+
Sbjct: 301 ETIEVEEQQEG-----------NDAEAQRREIELLRREGELPLEELLRSLPPQLLEGPSS 349
Query: 608 PPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGK----EGKTPSKEKKKKKKKGKE 663
P P +DSD GP+E +EE E K P ++ K+
Sbjct: 350 PSQTPS--------SHDSDT------RDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWH 395
Query: 664 EEEKAAKKKSKHKKSKDKE---------EGKEERRRRQQRPPRSRERTAADELEAFLGGG 714
+E + + ++++D+E EG+ + R E + + L+ + G
Sbjct: 396 PDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAY 455
Query: 715 APGGRHPGGGDYEEL 729
APG D +E+
Sbjct: 456 APGSGSSEDEDEDEV 470
Score = 33.1 bits (74), Expect = 0.94
Identities = 57/241 (23%), Positives = 85/241 (35%), Gaps = 43/241 (17%)
Query: 281 GHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE 340
G + PLAAN P+ + + VV + AP+ L PP + P PPS
Sbjct: 1288 GLSLPLAANQVPPTMVNNTGVVKI-----------VVRQAPRDGLTPVPPLAPAPRPPSS 1336
Query: 341 ALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLD 400
LP P + + GT+ A P P P P ++ V P+
Sbjct: 1337 GLPAVLNPRPTLTPGRLPTPTLGTARA-------PMPTPTLVRP-LLKLVHSPSPE---- 1384
Query: 401 RSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAG 460
+ + P + + S G A P+ P SP A
Sbjct: 1385 ---VSASAPGAAPLTI-SSPLHVPSSLPGPASSPMPI-------------PNSSP--LAS 1425
Query: 461 PVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPW 520
PV S +++ ++ PT PAPA + P + ++ AS P T+ T AP
Sbjct: 1426 PV-SSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVV 1484
Query: 521 P 521
P
Sbjct: 1485 P 1485
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 63.5 bits (153), Expect = 6e-10
Identities = 88/350 (25%), Positives = 117/350 (33%), Gaps = 64/350 (18%)
Query: 290 GQSPSPGS-QSPVVPAGAVSTGSSSPGTPQ-PAPQLPLNAAP--PSSVPPVPPSEA---- 341
G P PG Q P G G PG PQ P PQ + +P P P PP +
Sbjct: 70 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 129
Query: 342 ---LPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDR 398
PPP P P P+ G P + PPP +P +GP D
Sbjct: 130 QGPPPPPGKPQGPPPQG-------GNKP--QGPPPPGKP----QGPPP--------QGDN 168
Query: 399 LDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPP-- 456
RS + G Q G+ G P ++P+G PP
Sbjct: 169 KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG---------NKPQGPPPPG 219
Query: 457 LPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRR-----GTA 511
P GP P D ++ ++ + P K P PQ ++P+ P KP+ G
Sbjct: 220 KPQGPPPQGD----NKSQSARSPPGKPQGPPPQGGNQPQGP--PPPPGKPQGPPPQGGNK 273
Query: 512 PTRTAAPPWPGGVSVRTGPEKRSSTRPPAEME---PGKGEQASS---SESDPEGPIAAQM 565
P P P G + G + RSS PP + + P G Q P+GP
Sbjct: 274 PQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 333
Query: 566 LSFVMDDPDFESEGSDTQRRADDFPVRDDP----SDVTDEDEGPAEPPPP 611
P + +G Q + R P E P PPPP
Sbjct: 334 NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPP 383
Score = 52.4 bits (124), Expect = 1e-06
Identities = 74/305 (24%), Positives = 101/305 (33%), Gaps = 50/305 (16%)
Query: 278 RSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP 337
+SR SP P G P P PG PQ P P P
Sbjct: 107 KSRSPRSPPGKPQGPPPQGGNQPQGP-------PPPPGKPQGPP-------PQGGNKPQG 152
Query: 338 PSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPP---------PPEPVPAAEGPATVQ 388
P PPP P P P+ SR + P PP PP P +GP
Sbjct: 153 P----PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 208
Query: 389 SVEDFVPDDRLDRSFLEDTTPARDEKKVGAKA----AQQDSDSDGEALGGNPMVAGFQDD 444
+ P + P D K A++ Q G G P G
Sbjct: 209 GNK---PQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 265
Query: 445 VDLE--DQPRGSPP--LPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSS 500
+ ++P+G PP P GP P S+ + + P K P PQ ++P+
Sbjct: 266 PPPQGGNKPQGPPPPGKPQGPPPQG----GSKSRSSRSPPGKPQGPPPQGGNQPQ--GPP 319
Query: 501 IPASK-----PRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSES 555
P K P+ G P P P G + G + RS+ PP + + G +Q ++
Sbjct: 320 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ-GPPQQEGNNPQ 378
Query: 556 DPEGP 560
P P
Sbjct: 379 GPPPP 383
Score = 44.3 bits (103), Expect = 4e-04
Identities = 62/311 (19%), Positives = 112/311 (36%), Gaps = 27/311 (8%)
Query: 421 AQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAP 480
+Q++S S + GNP A Q ++P+G PP P G ++ + P
Sbjct: 24 SQEESPS---LIAGNPQGAPPQGG----NKPQG-PPSPPGKPQGPPPQGGNQPQGPPPPP 75
Query: 481 TKGPAPAPQQCSEPE-TKWSSIPASKPRRGTAPTRTAAPPW-PGGVSVRTGPEKRSSTRP 538
K P PQ ++P+ P P +G +PP P G + G + + P
Sbjct: 76 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 135
Query: 539 PAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDV 598
P + + G Q + P P Q P + + R+ + P
Sbjct: 136 PGKPQ-GPPPQGGNKPQGPPPPGKPQ-------GPPPQGDNKSRSSRSPPGKPQGPPPQG 187
Query: 599 TDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKK 658
++ +GP PP P+ P P K G + P + + + ++P + +
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGDNKSQSARSPPGKPQGPP 246
Query: 659 KKGKEEEE----KAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEAFLGGG 714
+G + + K + + +K +G + Q PP+ ++ + G
Sbjct: 247 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP----G 302
Query: 715 APGGRHPGGGD 725
P G P GG+
Sbjct: 303 KPQGPPPQGGN 313
Score = 43.5 bits (101), Expect = 7e-04
Identities = 66/276 (23%), Positives = 87/276 (31%), Gaps = 43/276 (15%)
Query: 278 RSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQ-PAPQ---LPLNAAPPSSV 333
+SR SP P G P P PG PQ P PQ P PP
Sbjct: 169 KSRSSRSPPGKPQGPPPQGGNQPQGP-------PPPPGKPQGPPPQGGNKPQGPPPPGKP 221
Query: 334 PPVPP------SEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATV 387
PP A PP P P P+ G P PPPP P P
Sbjct: 222 QGPPPQGDNKSQSARSPPGKPQGPPPQG-------GNQP---QGPPPPPGKPQGPPPQGG 271
Query: 388 QSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDL 447
+ P + + + +R + K Q G G P G
Sbjct: 272 NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK-PQGPPPQGGNQPQGPPPPPGKPQGPPP 330
Query: 448 E--DQPRGSPP--LPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPA 503
+ ++P+G PP P GP P S+ + + P K P Q+ + P+
Sbjct: 331 QGGNKPQGPPPPGKPQGPPPQG----GSKSRSARSPPGKPQGPPQQEGNNPQ-------G 379
Query: 504 SKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPP 539
P G P + APP P+ +RPP
Sbjct: 380 PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 62.0 bits (149), Expect = 2e-09
Identities = 90/319 (28%), Positives = 127/319 (39%), Gaps = 58/319 (18%)
Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGS--SSPGTPQPAPQLPLN--AAPPSSVPPVPP 338
ASP AA P + P PA AV T +SP P P+ P + AA P+ P P
Sbjct: 1001 ASPAAA-----VPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSP 1055
Query: 339 SEALPPPACPSAPA-----------PRRSIISRLFGTSPATEAAPPPPEP------VPAA 381
+ A+P P P++PA P ++ + TSPA A P P EP VP
Sbjct: 1056 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPTP 1114
Query: 382 EGPAT----VQSVED------FVPDDRLDRSFLEDTTPARDEKKVGAKA--AQQDSDSDG 429
E PA+ V + E+ VP + +F P +E A A ++S S
Sbjct: 1115 EEPASPAAAVPTPEEPASPAAAVPTPE-EPAFPAPAVPTPEESASAAVAVPTPEESASPA 1173
Query: 430 EALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQ 489
A+ A F V ++P PA VP+ +++ EE PA +
Sbjct: 1174 AAVPTPAESASFAAVVATLEEPTS----PAASVPTPAAMVATLEE------FTSPAASVP 1223
Query: 490 QCSEPETKWSSIPASKPRRGTAPTR---TAAPPWPGGVSVRTGPEKRSS--TRPPAEMEP 544
EP + +++ S P T+P T P +V T PE+ SS P EP
Sbjct: 1224 TSEEPASLAAAV--SNPEEPTSPAAAVPTLEEPTSSAAAVLT-PEELSSPAASVPTPEEP 1280
Query: 545 GKGEQASSSESDPEGPIAA 563
A S+ +P P AA
Sbjct: 1281 ASPAAAVSNLEEPASPAAA 1299
Score = 56.2 bits (134), Expect = 1e-07
Identities = 83/340 (24%), Positives = 122/340 (35%), Gaps = 46/340 (13%)
Query: 298 QSPVVPAGAVSTGS--SSPGTPQPAPQLPLN---AAPPSSVPPVPPSEALPPPACPSAPA 352
+ P PA AV T +SP P P+ P + A PP P P+ A+P P P++PA
Sbjct: 998 EEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE-EPTSPAAAVPTPEEPTSPA 1056
Query: 353 PRRSIISRLFGTSPATEAAPPPPEPV-PAAEGPATVQ--SVEDFVPDDRLDRSFLEDTTP 409
++ + TSPA A P P EP PAA P + S VP TP
Sbjct: 1057 --AAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPTPEEPTSPAAAVP------------TP 1101
Query: 410 ARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITL 469
A ++ S A+ A V ++P + P PA P P + +
Sbjct: 1102 EEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEP--AFPAPAVPTPEESAS- 1158
Query: 470 SSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTG 529
A VA PT + +P + +S A + A+ P P +
Sbjct: 1159 -----AAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLE 1213
Query: 530 PEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEG----SDTQRR 585
+ P EP A S+ +P P AA +++P + +
Sbjct: 1214 EFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP---TLEEPTSSAAAVLTPEELSSP 1270
Query: 586 ADDFPVRDDPSD---VTDEDEGPAEP----PPPPKLPLPA 618
A P ++P+ E PA P P P +PA
Sbjct: 1271 AASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPA 1310
Score = 40.8 bits (94), Expect = 0.005
Identities = 67/274 (24%), Positives = 90/274 (32%), Gaps = 41/274 (14%)
Query: 276 EARSRGHASPLAANGQSPS---PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPS 331
E S A P SP+ P + P PA AV T P P PA +P P
Sbjct: 1090 EPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT----PEEPASPAAAVPTPEEPAF 1145
Query: 332 SVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVE 391
P VP E A + P P S SPA A P P E A AT++
Sbjct: 1146 PAPAVPTPEE-SASAAVAVPTPEES-------ASPAA-AVPTPAESASFAAVVATLE--- 1193
Query: 392 DFVPDDRLDRSFLEDTTPARDEKKVGAKAAQ-QDSDSDGEALGGNPMVAGFQDDVDLEDQ 450
E T+PA A A ++ S ++ + A V ++
Sbjct: 1194 -------------EPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEE 1240
Query: 451 PRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPA---PAPQQCSEPETKWSSIPASKPR 507
P PA VP+ + SS PA P P++ + P S++
Sbjct: 1241 PTS----PAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASP 1296
Query: 508 RGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAE 541
PT A V P ++ PP E
Sbjct: 1297 AAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPME 1330
Score = 34.3 bits (77), Expect = 0.42
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 20/100 (20%)
Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342
ASP AA P S + VP V+ + P P P++P A P ++VPP+ E +
Sbjct: 1281 ASPAAAVSNLEEPASPAAAVPTPEVA---AIPAASVPTPEVP--AIPAAAVPPM---EEV 1332
Query: 343 PPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAE 382
P P G S T++ P E P E
Sbjct: 1333 SPIGVP------------FLGVSAHTDSVPISEEGTPVLE 1360
Score = 33.5 bits (75), Expect = 0.72
Identities = 48/176 (27%), Positives = 66/176 (37%), Gaps = 34/176 (19%)
Query: 461 PVPSQDITLSS----EEE----AEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAP 512
P P +DI ++S EEE A V+AP + PA S PE + S P TAP
Sbjct: 877 PFPHEDILVASIVSLEEEDVTAAAVSAPERATVPA-VTVSVPEGTAAVAAVSSPEE-TAP 934
Query: 513 TRTAAPPWPGGVSVR-TGPE--KRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFV 569
AA G +V PE + T P E + PEGP+
Sbjct: 935 AVAAAITQEGMSAVAGFSPEWAALAITVPITE-----------EDGTPEGPVTPATTVHA 983
Query: 570 MDDPDFESEGSDTQRR----ADDFPVRDDPSD------VTDEDEGPAEPPPPPKLP 615
++PD + T A P ++P+ +E PA PPP+ P
Sbjct: 984 PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEP 1039
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 62.0 bits (149), Expect = 2e-09
Identities = 86/354 (24%), Positives = 123/354 (34%), Gaps = 59/354 (16%)
Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342
A PL G P ++P+ P P P + PL+ PP P PP EA
Sbjct: 416 AKPLGKAGVQLEPQLEAPL--------NEEMPLLPPPE-ESPLSP-PPEESPTSPPPEAS 465
Query: 343 ----PPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDR 398
PP P++P P +SR SP + PPPE P + P + F P
Sbjct: 466 RLSPPPEELPASPLPEALHLSRPLEESPLS----PPPEESPLSPPPES----SPFSP--- 514
Query: 399 LDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPP-- 456
LE++ + E+ + A + EA +P+ F E+ P PP
Sbjct: 515 -----LEESPLSPPEESPPSPALETPLSPPPEA---SPLSPPF------EESPLSPPPEE 560
Query: 457 LPAGPVPSQDITLSSEEEAEVA-APTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRT 515
LP P P EE+ ++ P + P P + S + P S P P +
Sbjct: 561 LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP-----PEES 615
Query: 516 AAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDP-EGPIAAQMLSFVMDDPD 574
P P + PE + PP E + S P ++ + P
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
Query: 575 FESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPP-----------PPKLPLP 617
ES S + P +D ++ PA PPP P LPLP
Sbjct: 676 EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
Score = 57.8 bits (138), Expect = 4e-08
Identities = 106/430 (24%), Positives = 155/430 (36%), Gaps = 76/430 (17%)
Query: 293 PSPG--SQSPVVPAGAVSTGSSSPGTPQPAPQLPLN-AAPPSSVPPVPPSEALPPPACP- 348
P PG S SP++ A+S P +P P +LPL+ + PS P + P + LPPP P
Sbjct: 884 PPPGEPSLSPLLGEPALSEPGEPPLSPLPE-ELPLSPSGEPSLSPQLMPPDPLPPPLSPI 942
Query: 349 --SAPAPRRSIISRL---FGT-------SPA------TEAAPPP------PEPVP----- 379
+A P S + L FG SP T +PPP PEPVP
Sbjct: 943 ITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILP 1002
Query: 380 ----AAEGPATVQSVEDFVPD--DRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALG 433
+ GPA+ +E P L S + +P + A S +G
Sbjct: 1003 PSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPP---SQCSPPALPLSVPSPLSPIG 1059
Query: 434 GNPMVAGFQDDVDLEDQPRGSPPLPAGPV--PSQDITLSSEEEAEVAAPTKGPAPAPQQC 491
V G D+ +L + P P PS L S +++ P PAPA
Sbjct: 1060 ---KVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPM-GDLSCPAPSPAPALDDF 1115
Query: 492 S---EPETKWSSI--PASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRP-----PAE 541
S E I P S+P G P A+ G V PE+ + P +
Sbjct: 1116 SGLGEDTAPLDGIDAPGSQPEPGQTPGSLASEL--KGSPVLLDPEELAPVTPMEVYPECK 1173
Query: 542 MEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFE----SEGSDTQRRADDFPVRDDPSD 597
G+G E +P P+A + + D E S+G + P+ P
Sbjct: 1174 QTAGQGSPCEEQE-EPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDP 1232
Query: 598 V----------TDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEG 647
D PA +L + +DS L G +G K E+G+
Sbjct: 1233 EGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRR 1292
Query: 648 KTPSKEKKKK 657
+P++ + K+
Sbjct: 1293 SSPARSRIKQ 1302
Score = 50.4 bits (119), Expect = 6e-06
Identities = 87/351 (24%), Positives = 121/351 (34%), Gaps = 40/351 (11%)
Query: 282 HASPLAANG-QSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQL---PLNAAPPSSVPPVP 337
H SP+ SP P +S + P S P +P+L PL+ P PP
Sbjct: 814 HLSPVPEEPCLSPQP-EESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK--PPEE 870
Query: 338 PSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVP--AAEGPATVQSVE-DFV 394
P + P P P P +S L G +E PP P+P P+ S+ +
Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
Query: 395 PDDRLDRSFLEDTTPARD---------EKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDV 445
P D L T A E GAK DSD E+ P++ +
Sbjct: 931 PPDPLPPPLSPIITAAAPPALSPLGELEYPFGAK-----GDSDPESPLAAPIL-----ET 980
Query: 446 DLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASK 505
+ P + P PVP + S A+P P P QCS P + S +P +
Sbjct: 981 PISPPPEANCTDPE-PVPPMILPPSPGSPVGPASPIL-MEPLPPQCS-PLLQHSLVPQNS 1037
Query: 506 PRRGTAPTRTAAPPWPGGVSVRTGP-EKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQ 564
P P++ + P P V P K AE+ + E+ S E P A
Sbjct: 1038 P-----PSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATS 1092
Query: 565 MLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLP 615
L M D DDF + + D + P P P + P
Sbjct: 1093 PLPSPMG--DLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTP 1141
Score = 45.1 bits (105), Expect = 2e-04
Identities = 71/279 (25%), Positives = 100/279 (35%), Gaps = 57/279 (20%)
Query: 262 ETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG-TPQPA 320
+ E Q+ G+ L E P A +PSP S + G+ + + P TP+P
Sbjct: 2337 QVEPQSPGLGLRPQE--------PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ 2388
Query: 321 PQLPLN--AAPPSSVPPVPPSEALPPPACPS---APAPRRSIISRLFGTSPATEAAPPPP 375
P P + A PP S+P P S P S +P R + + F SP T P
Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT---PRFQ 2445
Query: 376 EPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGN 435
P P + P+ QS + F P + P +V KA S G GG
Sbjct: 2446 SPDPYSRPPSRPQSRDPFAPLHK---------PPRPQPPEVAFKAGSLAHTSLG--AGGF 2494
Query: 436 PMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAE-VAAPTKGP---APAPQQC 491
P LPAGP + S + V +P G P+P +
Sbjct: 2495 PAA------------------LPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRF 2536
Query: 492 SEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGP 530
+ P+ P+ KP P P P G++ GP
Sbjct: 2537 TFPQAVGE--PSLKP-----PVPQPGLPPPHGINSHFGP 2568
Score = 39.3 bits (90), Expect = 0.013
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
Query: 327 AAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPAT 386
+APP P PPS P PA P P ++ T P E PP P P+P A P +
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASP----PTEPLVE--LPTEPLAE--PPVPSPLPLASSPES 4958
Query: 387 VQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAK 419
+ P + ED+ P R +K G +
Sbjct: 4959 ARPKPRARPPEE-----GEDSRPPRLKKWKGVR 4986
Score = 38.9 bits (89), Expect = 0.017
Identities = 68/277 (24%), Positives = 94/277 (33%), Gaps = 26/277 (9%)
Query: 289 NGQSPSPGSQSPVVPAGAVSTGSSSPGTPQP--APQLPLNAAP-PSSVPPVPPSEALPPP 345
+G S S ++ +VS G Q PQ P+ P ++ P PP P P
Sbjct: 4121 SGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPK---PGP 4177
Query: 346 ACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLE 405
S I G A P P Q ++ + +L +S
Sbjct: 4178 VLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAV 4237
Query: 406 DTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGP--VP 463
TP E Q S G LG P + GF Q G+ P P GP +P
Sbjct: 4238 RQTPPYQEP------GTQTSPLQG-LLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLP 4290
Query: 464 SQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGG 523
+ LS+ V P P P P EP+ + S +P+ + PT PP G
Sbjct: 4291 APPGALST---GPVLGPVH-PTPPPSSPQEPK-RPSQLPSPSSQ---LPTEAQLPPTHPG 4342
Query: 524 VSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGP 560
GP + PP + P + A + S GP
Sbjct: 4343 TPKPQGP---TLEPPPGRVSPAAAQLADTLFSKGLGP 4376
Score = 38.1 bits (87), Expect = 0.029
Identities = 38/142 (26%), Positives = 56/142 (39%), Gaps = 14/142 (9%)
Query: 254 LEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSP-----GSQS-----PVVP 303
L LS QQ+ + Q + ++ ++++ P G SP G Q P
Sbjct: 4211 LRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ 4270
Query: 304 AGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFG 363
G + + P PQ P+LP S+ P + P PPP+ P P + S
Sbjct: 4271 TGPLQELGAGP-RPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP--S 4327
Query: 364 TSPATEAAPPPPEP-VPAAEGP 384
+ TEA PP P P +GP
Sbjct: 4328 SQLPTEAQLPPTHPGTPKPQGP 4349
Score = 35.8 bits (81), Expect = 0.14
Identities = 38/174 (21%), Positives = 56/174 (32%), Gaps = 8/174 (4%)
Query: 448 EDQPRGSPP--LPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASK 505
E+ P PP P P P + T E + ++ P + +P PE S P +
Sbjct: 436 EEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPL----PEALHLSRPLEE 491
Query: 506 PRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQM 565
P + P P S P + S PP E P + S P++
Sbjct: 492 SPLSPPPEESPLSPPPE--SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549
Query: 566 LSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAF 619
+ P E S + P ++ +E P PPP P F
Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603
Score = 35.8 bits (81), Expect = 0.14
Identities = 107/483 (22%), Positives = 161/483 (33%), Gaps = 90/483 (18%)
Query: 237 ETLLRQLETNQLDMDATLEELSVQQETEDQ---NYGIFLEMMEARSRGHASPLAANGQSP 293
E LL+QL+ +ELS+ TE N+ +F G P+ NGQS
Sbjct: 4549 EALLKQLK----------QELSLLPLTEPAITANFSLFAPF------GSGCPV--NGQSQ 4590
Query: 294 SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAP 353
G+ +GA+ TG L PPSS+PP PP P+
Sbjct: 4591 LRGAFG----SGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPP------------PSV 4634
Query: 354 RRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDE 413
++ +++ G +P+ E P + A + ++ + D L TP ++
Sbjct: 4635 QQKMVN---GVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAAL----PTPPHNQ 4687
Query: 414 KKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQD------I 467
+ + +DSDS + A + + E+ PR P L +G +D I
Sbjct: 4688 TEDVRMESDEDSDSPDSI-----VPASSPESILGEEAPR-FPHLGSGRWEQEDRALSPVI 4741
Query: 468 TLSSEEEAEVAAPTK--GPAPAPQQCSEPETKWS-------------SIPASKPRRG--T 510
L V TK G P T W S A+K G
Sbjct: 4742 PLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMV 4801
Query: 511 APTRTAAPPWPGGVSVRTGPEK--RSSTRP-PAEME-PGKGEQASSSESDPEGPIAAQML 566
A + P V PE R+ T P E E PG E+ +S GP +
Sbjct: 4802 AVAELLSMKIPNSYEV-LFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQF 4860
Query: 567 SFVMDDPDFESEGSDTQRRADDFPVRDDPS-----------DVTDEDEGPAEPPPPPKLP 615
V+ +S+ + P + P+ DV P E P PP P
Sbjct: 4861 DAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSP 4920
Query: 616 L-PAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSK 674
L P+ L L E +P + K + + EE E + + K
Sbjct: 4921 LAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLK 4980
Query: 675 HKK 677
K
Sbjct: 4981 KWK 4983
Score = 33.1 bits (74), Expect = 0.94
Identities = 32/121 (26%), Positives = 38/121 (31%), Gaps = 23/121 (19%)
Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAP----------------PSSVPPV 336
P G Q+ P +ST PG P P P P P PP
Sbjct: 2843 PELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQ 2902
Query: 337 PPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPE------PVPAAEGPATVQSV 390
P P P AP + G P +APP PE P P +GP +
Sbjct: 2903 RP-RFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGL 2961
Query: 391 E 391
E
Sbjct: 2962 E 2962
Score = 32.7 bits (73), Expect = 1.2
Identities = 71/307 (23%), Positives = 103/307 (33%), Gaps = 61/307 (19%)
Query: 284 SPLAANGQSPS--PGSQSP-VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE 340
SPL + P P S+ P + P S P P +PQ P P +
Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
Query: 341 ALPPPACPSAPAPRRSIISRLFGTSPATE---AAPPPPEPV-----------PAAEGPAT 386
P P A P S SP TE +P P EP P +E P
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
Query: 387 VQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVD 446
E+ L++ L P + ++ G A ++ G P ++ +
Sbjct: 843 SPRPEESHLSPELEKPPL-SPRPEKPPEEPGQCPAPEELPLFPPP--GEPSLSPLLGEPA 899
Query: 447 LEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKP 506
L + G PPL P+P +++ LS E ++ P P P S
Sbjct: 900 LSEP--GEPPL--SPLP-EELPLSPSGEPSLSPQLMPPDPLPPPLS-------------- 940
Query: 507 RRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQML 566
P TAA P + P E+E G + +SDPE P+AA +L
Sbjct: 941 -----PIITAAAP--------------PALSPLGELEYPFG---AKGDSDPESPLAAPIL 978
Query: 567 SFVMDDP 573
+ P
Sbjct: 979 ETPISPP 985
Score = 31.6 bits (70), Expect = 2.7
Identities = 90/391 (23%), Positives = 123/391 (31%), Gaps = 74/391 (18%)
Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP---- 348
P P P V+TG+ P P P PPS LPPPA
Sbjct: 2568 PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPS-VLPPPAPDGSLP 2626
Query: 349 ------------SAPAPRRSIISRLFGTSPATEAAPPPPEPVPAA------EGPATVQSV 390
++P +R G+S AT P +P + E Q +
Sbjct: 2627 YLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRL 2686
Query: 391 EDFVPDDRLDRSFL--EDTTPARDEKKV---GAKAAQQDSDSDGEALGGNPMVAGFQDDV 445
+ + ++ R+ L E T A V G+ A+ S + + G AG QD
Sbjct: 2687 RELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKS 2746
Query: 446 DL-------------------EDQPRGSPPLPAGPVPSQDIT----LSSEEEAEVAAPTK 482
L D PP PA P S D+ + + AP
Sbjct: 2747 SLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATP-SSMDVNSRQLVGGSQAFYQRAPYP 2805
Query: 483 GPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEM 542
G P QQ + + + A+ R + + P G P STR P
Sbjct: 2806 GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG 2865
Query: 543 EPGKGEQASSSESDPEGPIAAQMLSF------VMDDPDFESEGSDTQRRADDFPVRDDPS 596
EP G P GP AQ + + G +R +PV +DP
Sbjct: 2866 EPVPG---------PAGP--AQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPH 2914
Query: 597 DVTDED-EGPAE---PPPPPKLPLPAFRLKN 623
+ E G A PP P P PA L N
Sbjct: 2915 RLAPEGLRGLAVSGLPPQKPSAP-PAPELNN 2944
Score = 31.2 bits (69), Expect = 3.6
Identities = 28/97 (28%), Positives = 35/97 (36%), Gaps = 6/97 (6%)
Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLP--LNAAPPSSVP-PVPPSEA---LPPPA 346
P PG+ PA A + SP TP P SVP P P E LPP
Sbjct: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV 2167
Query: 347 CPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEG 383
P+ ++ + P APP P P+ G
Sbjct: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTG 2204
>gi|149944516 tet oncogene family member 3 [Homo sapiens]
Length = 1660
Score = 61.2 bits (147), Expect = 3e-09
Identities = 89/377 (23%), Positives = 142/377 (37%), Gaps = 52/377 (13%)
Query: 239 LLRQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQ 298
L R+ T + D + + Q+ +FLE + S S +A G P P S
Sbjct: 372 LQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSP 431
Query: 299 SPVVPAGAVSTGSSSPGTPQPAPQLPLNAAP---PSSVPPVPPSEALPPPACPSAPAPRR 355
P +P TP P AAP PS P+ ++ P A P P R+
Sbjct: 432 VPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQ 491
Query: 356 SIISRLFGTSPAT-EAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEK 414
++ L SPA+ E PP P+PA++G A E + L +P+RD
Sbjct: 492 IVLEGL--RSPASQEVQAHPPAPLPASQGSAVPLPPEPSLA--------LFAPSPSRDSL 541
Query: 415 KVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEE 474
+ + S PM A QP + PLP +++ E E
Sbjct: 542 LPPTQEMRSPS----------PMTAL---------QPGSTGPLPPADDKLEELIRQFEAE 582
Query: 475 AEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRS 534
+ GP P Q +PE + + +PA + T + G V+V + S
Sbjct: 583 FGDSFGLPGPPSVPIQ--DPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHS 640
Query: 535 STRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFV------MDDPDFESEGSDTQRRADD 588
E G G++A+ +++ E P+ + F+ +D P + +R +
Sbjct: 641 --------EEG-GQEATPTKA--ENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAE 689
Query: 589 FPVRDDPSDVTDEDEGP 605
FP D + ++DEGP
Sbjct: 690 FPTCDCVEQIVEKDEGP 706
Score = 41.2 bits (95), Expect = 0.003
Identities = 92/392 (23%), Positives = 129/392 (32%), Gaps = 85/392 (21%)
Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE--ALPPPACPSA 350
P P +P A + SP P +PQ L A S P VPP E + P +
Sbjct: 236 PQPSHSTP--QASCPLPEALSPPAPFRSPQSYLRA---PSWPVVPPEEHSSFAPDSSAFP 290
Query: 351 PAPRRSIISRLFGTS--PATEAAP---PPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLE 405
PA R+ +GT PAT + P P P P AE + S D++
Sbjct: 291 PATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYI----------- 339
Query: 406 DTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSP-PLPAGPVPS 464
Q EAL P V + P SP P P+ +
Sbjct: 340 -----------------QSVFKRPEALPTKPKVK--------VEAPSSSPAPAPSPVLQR 374
Query: 465 QDITLSSEEEAEVAAPT------------------KGPAPAPQQCSEPETKWSSIPASK- 505
+ T SSE + A T PAP + S P W P+S
Sbjct: 375 EAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAP--GWWPPPSSPV 432
Query: 506 PRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQM 565
PR P + P G EK + P+ +P + +++ E+ P P Q+
Sbjct: 433 PRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQI 492
Query: 566 LSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEP-PPPPKLPLPAFRLKND 624
+ + P + V+ P +G A P PP P L L A D
Sbjct: 493 VLEGLRSPASQE-------------VQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRD 539
Query: 625 SDLFGL-GLEEAGPKESSEEGKEGKTPSKEKK 655
S L + P + + G G P + K
Sbjct: 540 SLLPPTQEMRSPSPMTALQPGSTGPLPPADDK 571
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.131 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,855,899
Number of Sequences: 37866
Number of extensions: 2571017
Number of successful extensions: 61387
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1022
Number of HSP's successfully gapped in prelim test: 2298
Number of HSP's that attempted gapping in prelim test: 21766
Number of HSP's gapped (non-prelim): 23338
length of query: 729
length of database: 18,247,518
effective HSP length: 110
effective length of query: 619
effective length of database: 14,082,258
effective search space: 8716917702
effective search space used: 8716917702
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.