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Search of human proteins with 18466802
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18466802 Ras and Rab interactor 2 [Homo sapiens]
(895 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18466802 Ras and Rab interactor 2 [Homo sapiens] 1808 0.0
gi|40353729 Ras and Rab interactor 3 [Homo sapiens] 323 3e-88
gi|68989256 ras inhibitor RIN1 [Homo sapiens] 236 9e-62
gi|38348206 Ras and Rab interactor-like [Homo sapiens] 108 2e-23
gi|7657496 RAB guanine nucleotide exchange factor (GEF) 1 [Homo ... 58 3e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 49 3e-05
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 47 8e-05
gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] 47 1e-04
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi... 47 1e-04
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi... 47 1e-04
gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens] 46 1e-04
gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo s... 46 1e-04
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens] 46 2e-04
gi|54860079 nadrin isoform 1 [Homo sapiens] 45 3e-04
gi|54860105 nadrin isoform 2 [Homo sapiens] 45 3e-04
gi|221219026 pleckstrin homology-like domain, family B, member 1... 45 4e-04
gi|221219024 pleckstrin homology-like domain, family B, member 1... 45 4e-04
gi|38424073 pleckstrin homology-like domain, family B, member 1 ... 45 4e-04
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 45 4e-04
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 44 5e-04
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 44 5e-04
gi|146134388 YLP motif containing 1 [Homo sapiens] 44 5e-04
gi|71979663 growth factor receptor-bound protein 14 [Homo sapiens] 44 9e-04
gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre... 43 0.001
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 43 0.001
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo... 42 0.002
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo... 42 0.002
gi|38373682 pleckstrin homology domain containing family G membe... 42 0.002
gi|111154084 pleckstrin homology domain containing family G memb... 42 0.002
gi|111154088 pleckstrin homology domain containing family G memb... 42 0.002
>gi|18466802 Ras and Rab interactor 2 [Homo sapiens]
Length = 895
Score = 1808 bits (4684), Expect = 0.0
Identities = 895/895 (100%), Positives = 895/895 (100%)
Query: 1 MTAWTMGARGLDKRGSFFKLIDTIASEIGELKQEMVRTDVNLENGLEPAETHSMVRHKDG 60
MTAWTMGARGLDKRGSFFKLIDTIASEIGELKQEMVRTDVNLENGLEPAETHSMVRHKDG
Sbjct: 1 MTAWTMGARGLDKRGSFFKLIDTIASEIGELKQEMVRTDVNLENGLEPAETHSMVRHKDG 60
Query: 61 GYSEEEDVKTCARDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFL 120
GYSEEEDVKTCARDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFL
Sbjct: 61 GYSEEEDVKTCARDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFL 120
Query: 121 VHKSTKMQKKVLSLRLPCEFGAPLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRD 180
VHKSTKMQKKVLSLRLPCEFGAPLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRD
Sbjct: 121 VHKSTKMQKKVLSLRLPCEFGAPLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRD 180
Query: 181 VLPFTLKLPYAISTAKSEAQLEELAQMGLNFWSSPADSKPPNLPPPHRPLSSDGVCPASL 240
VLPFTLKLPYAISTAKSEAQLEELAQMGLNFWSSPADSKPPNLPPPHRPLSSDGVCPASL
Sbjct: 181 VLPFTLKLPYAISTAKSEAQLEELAQMGLNFWSSPADSKPPNLPPPHRPLSSDGVCPASL 240
Query: 241 RQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSGGLKRPSTRTPNANG 300
RQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSGGLKRPSTRTPNANG
Sbjct: 241 RQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSGGLKRPSTRTPNANG 300
Query: 301 TERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPR 360
TERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPR
Sbjct: 301 TERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPR 360
Query: 361 LKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRP 420
LKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRP
Sbjct: 361 LKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRP 420
Query: 421 PCHGGRQRLSDMSISTSSSDSLEFDRSMPLFGYEADTNSSLEDYEGESDQETMAPPIKSK 480
PCHGGRQRLSDMSISTSSSDSLEFDRSMPLFGYEADTNSSLEDYEGESDQETMAPPIKSK
Sbjct: 421 PCHGGRQRLSDMSISTSSSDSLEFDRSMPLFGYEADTNSSLEDYEGESDQETMAPPIKSK 480
Query: 481 KKRSSSFVLPKLVKSQLQKVSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFL 540
KKRSSSFVLPKLVKSQLQKVSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFL
Sbjct: 481 KKRSSSFVLPKLVKSQLQKVSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFL 540
Query: 541 QENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCIL 600
QENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCIL
Sbjct: 541 QENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCIL 600
Query: 601 KPLKGHVEAMLKDFHMADGSWKQLKENLQLVRQRNPQELGVFAPTPDFVDVEKIKVKFMT 660
KPLKGHVEAMLKDFHMADGSWKQLKENLQLVRQRNPQELGVFAPTPDFVDVEKIKVKFMT
Sbjct: 601 KPLKGHVEAMLKDFHMADGSWKQLKENLQLVRQRNPQELGVFAPTPDFVDVEKIKVKFMT 660
Query: 661 MQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEY 720
MQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEY
Sbjct: 661 MQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEY 720
Query: 721 MMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSETRDTLRQWHKRRTTNRT 780
MMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSETRDTLRQWHKRRTTNRT
Sbjct: 721 MMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSETRDTLRQWHKRRTTNRT 780
Query: 781 IPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQICAEKFKVGDPEEYSLFLFV 840
IPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQICAEKFKVGDPEEYSLFLFV
Sbjct: 781 IPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQICAEKFKVGDPEEYSLFLFV 840
Query: 841 DETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGIIFQNGEEDLTTS 895
DETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGIIFQNGEEDLTTS
Sbjct: 841 DETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGIIFQNGEEDLTTS 895
>gi|40353729 Ras and Rab interactor 3 [Homo sapiens]
Length = 985
Score = 323 bits (829), Expect = 3e-88
Identities = 207/573 (36%), Positives = 304/573 (53%), Gaps = 34/573 (5%)
Query: 311 PPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGT-KPTPIPPPRLKKQASFLE 369
PP + +PR + + Q + E + H LP T K P+PPPR K+ + L
Sbjct: 414 PPQGTSDGPEDTPRESTEQGQDT--EVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLA 471
Query: 370 AEGGAKTLSGGRPGAGPELELGTAGSPG-GAPPEAAPGDCTRAPPPS----SESRPPCHG 424
+ A + LE T G P G P + G T+ PP S+S P G
Sbjct: 472 STLPAPLENAELCTQAMALETPTPGPPREGQSPASQAG--TQHPPAQATAHSQSSPEFKG 529
Query: 425 GRQRLSD-MSISTSSSDSLEFDRSMPLFGYEADTNSSLEDYEGESDQETMAPPIKSKKKR 483
LSD + +S ++D + S T LE + S KK+
Sbjct: 530 SLASLSDSLGVSVMATDQDSYSTS--------STEEELEQFSSPS-----------VKKK 570
Query: 484 SSSFVLPKLVKSQLQKVSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLQEN 543
S + + S +F +F++ +++ +++ EL++DK +YFG LVQDY + E
Sbjct: 571 PSMILGKARHRLSFASFSSMFHAFLSNNRKLYKKVVELAQDKGSYFGSLVQDYKVYSLEM 630
Query: 544 KECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIE-SLIPEDQIDVVLEKAMHKCILKP 602
SST+MLQ IR MTQ+K+YL QS+EL ++ +L E++++ ++E A++KC+LKP
Sbjct: 631 MARQTSSTEMLQEIRTMMTQLKSYLLQSTELKALVDPALHSEEELEAIVESALYKCVLKP 690
Query: 603 LKGHVEAMLKDFHMADGSWKQLKENLQLVRQRNPQELGVFAPTPDFVDVEKIKVKFMTMQ 662
LK + + L H DGS +QLKEN ++ +LGV P+ +EKI KF +M
Sbjct: 691 LKEAINSCLHQIHSKDGSLQQLKENQLVILATTTTDLGVTTSVPEVPMMEKILQKFTSMH 750
Query: 663 KMYSPEKKVMLLLRVCKLIYTVME-NNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYM 721
K YSPEKK+ +LL+ CKLIY M N G+ YGADDFLPVL YV+A+ ++ E+ +EYM
Sbjct: 751 KAYSPEKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYM 810
Query: 722 MELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSETRDTLRQWHKRRTTNRTI 781
MEL+DP+L GEG YYLT+ YGAL IK++ + R LS E +D++ +W +RRT N+
Sbjct: 811 MELMDPALQLGEGSYYLTTTYGALEHIKSYDKITVTRQLSVEVQDSIHRWERRRTLNKAR 870
Query: 782 PSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQICAEKFKVGDPEEYSLFLFVD 841
S Q+++ V++ E +TL R + +C CAEKF V P+ + LF+ VD
Sbjct: 871 ASRSSVQDFICVSYLEPEQ--QARTLASRADTQAQALCAQCAEKFAVERPQAHRLFVLVD 928
Query: 842 ETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYK 874
QLA+D P IK L FHFVY+
Sbjct: 929 GRCFQLADDALPHCIKGYLLRSEPKRDFHFVYR 961
Score = 154 bits (389), Expect = 4e-37
Identities = 147/467 (31%), Positives = 210/467 (44%), Gaps = 71/467 (15%)
Query: 64 EEEDVKTCARDSGYDSLSNR--LSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFLV 121
EE+ ++ C + + L +R +SIL++L+ T P+WLQLSL + E A +L G+FLV
Sbjct: 28 EEDGMRLCLPANPKNCLPHRRGISILEKLIKTCPVWLQLSLGQAEVARILHRVVAGMFLV 87
Query: 122 HKSTKMQKKVLSLRLPC--EFGAPLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISR 179
+ + ++ VL + P E A + E+ IKE LEGS + F D+FRLIAFYC+SR
Sbjct: 88 RRDSSSKQLVLCVHFPSLNESSAEVLEYTIKEEKSILYLEGSALVFEDIFRLIAFYCVSR 147
Query: 180 DVLPFTLKLPYAISTAKSEAQLEELAQMGLNFWSS----PADSKPPNLPPPHRPLSSDGV 235
D+LPFTL+LP AI A S LE +A +GL FW S P + P PP R V
Sbjct: 148 DLLPFTLRLPQAILEASSFTDLETIANLGLGFWDSSLNPPQERGKPAEPPRDRAPGFPLV 207
Query: 236 CPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSGGLKRPSTRT 295
+SLR + E+E S N L F+NP+F+ +D S L P+ +
Sbjct: 208 --SSLRPT-------AHDANCACEIELSVGNDRLWFVNPIFI----EDCSSAL--PTDQP 252
Query: 296 PNANGTERTRSP------------PPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKH 343
P N R P P RPPPP P L + P +
Sbjct: 253 PLGNCPARPLPPTSDATSPTSRWAPRRPPPP-------PPVLPLQPCSPAQPPVLPALAP 305
Query: 344 GNVA-LPGTKPTPIP--------PPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAG 394
LP + P P P PP Q + E L G GP E A
Sbjct: 306 APACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCE----RLPCPTAGLGPLRE--EAM 359
Query: 395 SPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSD-MSISTSSSD-SLEFDR-SMPLF 451
PG A ++P APP ++ P R+R+S+ +S+ S + E D+ S+P
Sbjct: 360 KPGAA---SSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQ 416
Query: 452 GYEADTNSSLEDYEGESDQETMAPPIKSKKKRSSSFVLPKLVKSQLQ 498
G T+ ED ES ++ +K+ S +P+L ++ Q
Sbjct: 417 G----TSDGPEDTPRESTEQGQDTEVKASDPHS----MPELPRTAKQ 455
>gi|68989256 ras inhibitor RIN1 [Homo sapiens]
Length = 783
Score = 236 bits (601), Expect = 9e-62
Identities = 157/455 (34%), Positives = 238/455 (52%), Gaps = 30/455 (6%)
Query: 395 SPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLS-DMSISTSSSDSLEFDRSMPLFGY 453
SP PP P A P +E PPC R+ S + S SL S+
Sbjct: 258 SPPAVPPPPVPV-LPGAVPSQTERLPPCQLLRRESSVGYRVPAGSGPSLPPMPSLQEVDC 316
Query: 454 EADTNSSLEDYEGESDQETMAPPIKSKKKRSSSFVLPKLVKSQLQKVSGVFSSFMTPEKR 513
+ ++S E G +P + ++ L+ +S F S + PE++
Sbjct: 317 GSPSSSEEEGVPGSRGSPATSPHLGRRRPL-------------LRSMSAAFCSLLAPERQ 363
Query: 514 MVRRIAELSRDKCTYFGCLVQDYVSFLQENKECHVSSTDMLQTIRQFMTQVKNYLSQSSE 573
+ R A L +D+ T G LVQD ++ ++ E LQ IRQ +++ + LS +E
Sbjct: 364 VGRAAAALMQDRHTAAGQLVQDLLTQVRAGPE-----PQELQGIRQALSRARAMLS--AE 416
Query: 574 LDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHMADGSWKQLKENLQLVRQ 633
L P E L+ +++ VLEK++H +LKPL+ + A L+ ADGS +L E L+L R
Sbjct: 417 LGP--EKLLSPKRLEHVLEKSLHCSVLKPLRPILAARLRRRLAADGSLGRLAEGLRLARA 474
Query: 634 RNPQELGVFAPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMY 693
+ P G P V++E+++ K + + + YSP +V LL+ CKL+Y + G
Sbjct: 475 QGPGAFGSHLSLPSPVELEQVRQKLLQLLRTYSPSAQVKRLLQACKLLYMALRTQEGEGA 534
Query: 694 GADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQE 753
GAD+FLP+L+ V+A CD+ EL E EYM ELL+PSLL GEGGYYLTS +L+L+ +
Sbjct: 535 GADEFLPLLSLVLAHCDLPELLLEAEYMSELLEPSLLTGEGGYYLTSLSASLALLSGLGQ 594
Query: 754 EQAARLLS-SETRDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPY 812
L E R +L W +RR +P+ FQ+ LRVA+Q+ +SGCT KTL V P
Sbjct: 595 AHTLPLSPVQELRRSLSLWEQRR-----LPATHCFQHLLRVAYQDPSSGCTSKTLAVPPE 649
Query: 813 ITTEDVCQICAEKFKVGDPEEYSLFLFVDETWQQL 847
+ + Q+CA KF+V P + LFL+ ++ + +L
Sbjct: 650 ASIATLNQLCATKFRVTQPNTFGLFLYKEQGYHRL 684
Score = 133 bits (334), Expect = 8e-31
Identities = 116/373 (31%), Positives = 164/373 (43%), Gaps = 72/373 (19%)
Query: 84 LSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFLVHKSTKMQKKVLSLRLPCEFGAP 143
+S+ +RLL T P+WLQL + A +L+ +PPG FLV KS Q + L +RLP G
Sbjct: 56 VSLRERLLLTRPVWLQLQANAAAALHMLRTEPPGTFLVRKSNTRQCQALCMRLPEASGPS 115
Query: 144 -LKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKSEAQLE 202
+ I ES SLEGS + F DL +LI YC +RD+L L+LP AI A + +LE
Sbjct: 116 FVSSHYILESPGGVSLEGSELMFPDLVQLICAYCHTRDILLLPLQLPRAIHHAATHKELE 175
Query: 203 ELAQMGLNFWSSPADSKPPNLPPPHRPLSSDGVCPASLRQLCLINGVHSIKTRTPSELEC 262
++ +G+ FWSS + K P + V P +K R+P EL+
Sbjct: 176 AISHLGIEFWSSSLNIKAQRGP------AGGPVLP-------------QLKARSPQELD- 215
Query: 263 SQTNGALCFINPLFLKVHSQDLSGGLKRPSTRTPNANGTERTRSP--PPRPPPPAINSLH 320
T ALCF NPLF DL + R+ + T SP PP PPP +
Sbjct: 216 QGTGAALCFFNPLF----PGDLGPTKREKFKRSFKVRVSTETSSPLSPPAVPPPPV---- 267
Query: 321 TSPRLARTETQTSMPETVNHNKHGNVALPGTKPTP---IPPPRLKKQASFLEAEGGAKTL 377
LPG P+ +PP +L ++ E+ G +
Sbjct: 268 -------------------------PVLPGAVPSQTERLPPCQLLRR----ESSVGYRVP 298
Query: 378 SGGRPGAG--PELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSIS 435
+G P P L+ GSP + E PG +R P +S H GR+R S+S
Sbjct: 299 AGSGPSLPPMPSLQEVDCGSPSSSEEEGVPG--SRGSPATSP-----HLGRRRPLLRSMS 351
Query: 436 TSSSDSLEFDRSM 448
+ L +R +
Sbjct: 352 AAFCSLLAPERQV 364
>gi|38348206 Ras and Rab interactor-like [Homo sapiens]
Length = 452
Score = 108 bits (271), Expect = 2e-23
Identities = 78/243 (32%), Positives = 127/243 (52%), Gaps = 15/243 (6%)
Query: 550 STDMLQTIRQFMTQVKNYLSQSSELDPPIESLIP-----EDQIDVVLEKAMHKCILKPLK 604
+T++LQ +R +T ++++L++ S + S P ++ LE A+ + +L PLK
Sbjct: 185 ATELLQDVRHLLTDLQDHLAKDSYIRAVFGSRGPGLPKKDEDPGPALETAVCQAVLAPLK 244
Query: 605 GHVEAMLKDFHMADGSWKQLKENLQLVRQR----NPQELGVFAPTPDFVDVEKIKVKFMT 660
+ L+ + ++L+ +R Q G +P +I +
Sbjct: 245 PALWTRLRTLRAPE--LRRLRRRQTALRAGAGPPGAQGPGPEGQSPAPALRSRIHERLAH 302
Query: 661 MQKMYSPEKKVMLLLRVCKLIYTVMENNSGR-MYGADDFLPVLTY-VIAQCDMLELDTEI 718
+ +P +KV LLL VC+ +Y + + GAD FLP LT +I D+ + ++
Sbjct: 303 LHAACAPRRKVALLLEVCRDVYAGLARGENQDPLGADAFLPALTEELIWSPDIGDTQLDV 362
Query: 719 EYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEE--QAARLLSSETRDTLRQWHKRRT 776
E++MELLDP L GE GYYLT+ +GAL I ++Q E +A R LSSE R +L QWH+RRT
Sbjct: 363 EFLMELLDPDELRGEAGYYLTTWFGALHHIAHYQPETDRAPRGLSSEARASLHQWHRRRT 422
Query: 777 TNR 779
+R
Sbjct: 423 LHR 425
>gi|7657496 RAB guanine nucleotide exchange factor (GEF) 1 [Homo
sapiens]
Length = 491
Score = 58.2 bits (139), Expect = 3e-08
Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 13/153 (8%)
Query: 624 LKENLQLVRQRNPQELGVFAPTPDFVDVEKIKVKFMT----MQKMYSPEKKVMLLLRVCK 679
+++ ++ +R PQ L V D +V + VK +T M P K+ + + K
Sbjct: 238 IQKRIRALRWVTPQMLCV-PVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSK 296
Query: 680 LIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPS-LLHGEGGYYL 738
I+ ++ ADDFLP L Y++ + + L + I+Y+ +PS L+ GE GYY
Sbjct: 297 HIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYF 356
Query: 739 TSAYGALSLIK-------NFQEEQAARLLSSET 764
T+ A++ I+ N +E R +S +T
Sbjct: 357 TNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQT 389
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 48.5 bits (114), Expect = 3e-05
Identities = 41/157 (26%), Positives = 60/157 (38%), Gaps = 21/157 (13%)
Query: 286 GGLKRPSTRT---------------PNANGTERTRSPPPRPPPPAINSLHTSPRLARTET 330
GGL+RP++R+ P+A GT R + P +P P + +L +
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291
Query: 331 QTSMPETVNHNKHGNVALPGTKPTPIPPP---RLKKQASFLEAEGGAKTLSGGRPGAGPE 387
++ + + GTK P+PPP A+ + A L P
Sbjct: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351
Query: 388 LELGTAGSPGGAPPEAAPGDCTRAP---PPSSESRPP 421
L T SP PP AP T P PPS ++ PP
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388
Score = 36.6 bits (83), Expect = 0.11
Identities = 62/235 (26%), Positives = 80/235 (34%), Gaps = 48/235 (20%)
Query: 214 SPADSKPPNLPP----------PHRPLSSDGVCPASLRQLCLINGVHSIKTRTPSELECS 263
SP PP PP P P S G P S ++ + + + P L
Sbjct: 779 SPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA- 837
Query: 264 QTNGALCFINPLFLKVHSQDLSGGL---KRPSTRTPNAN--GTERTRSPPPRPPPP---A 315
PL S S L +RP T P+ + G T + P PPPP +
Sbjct: 838 ----------PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 887
Query: 316 INSLHTSPRLA-RTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGA 374
+S + P LA + + TS PE + G P PPP +AE A
Sbjct: 888 PSSTLSGPDLAGHSSSATSTPEELRGYDSG----PEGGAAASPPP---------DAELAA 934
Query: 375 KTLSGGRPGAGPELEL-GTAGSPGGAPPEAAPGD----CTRAPPPSSESRPPCHG 424
+ G P L G G+P PP PG CT ES P G
Sbjct: 935 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 989
Score = 36.2 bits (82), Expect = 0.14
Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 10/121 (8%)
Query: 306 SPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQA 365
SPP PP A S+ T P A QT P V H ++ P + P P QA
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH----SLTSPSLQAPPSPLALSSLQA 414
Query: 366 S------FLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAPPPSSESR 419
+ L+A T+S + A A +P +PP AP +PP +
Sbjct: 415 TTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474
Query: 420 P 420
P
Sbjct: 475 P 475
Score = 35.0 bits (79), Expect = 0.31
Identities = 58/244 (23%), Positives = 80/244 (32%), Gaps = 27/244 (11%)
Query: 219 KPPNLPPPHRPLSSDGVCPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLK 278
+PP P P P V PA+LR L G R P GA P
Sbjct: 28 RPPGSPRPPPP-----VTPAALRVL----GAAGAVGRKPLAERAGGIGGATI---PESAP 75
Query: 279 VHSQDLSGGL--KRPSTRTPNANGTERT-----RSPPPRPPPPAINSLHTSPRLARTETQ 331
S G + P++R P + ER SP P P + L + +
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135
Query: 332 TSMPETVNHNK------HGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAG 385
S ETV K ++ + T P P A + + RP
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195
Query: 386 PELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSSSDSLEFD 445
T G +A T P P++ RP GG QR + S+S+S++
Sbjct: 196 ARPRPPTEGPRKSV--SSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 446 RSMP 449
RS P
Sbjct: 254 RSGP 257
Score = 35.0 bits (79), Expect = 0.31
Identities = 48/174 (27%), Positives = 64/174 (36%), Gaps = 16/174 (9%)
Query: 288 LKRPSTRTPNANGTERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVA 347
L P + P + SP +PPP A +L T P A S P + ++
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 820
Query: 348 L-PGTKPTPIPPPRLKKQASFLE---AEGGAKTLSGGR--PGAGPELELGTAGSPGGAPP 401
+ P P P PP L A L+ + + TL R P GP+ T+ S
Sbjct: 821 MSPLATPPPQAPPVL--AAPLLQVPPSPPASPTLQAPRRPPTPGPD----TSVSGPRLTL 874
Query: 402 EAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSSSDSLEFDRSMPLFGYEA 455
APG PPP S S G S +TS+ + L S P G A
Sbjct: 875 ALAPG----PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 924
Score = 34.7 bits (78), Expect = 0.41
Identities = 38/137 (27%), Positives = 51/137 (37%), Gaps = 30/137 (21%)
Query: 288 LKRPSTRTPNANGTERTR---SPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHG 344
L PS + PNA + SPPP PP A S SP ++ + T S
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP------- 697
Query: 345 NVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAA 404
++A P + P PP + +S P A P + A P APP
Sbjct: 698 SLAAPPLQVPPSPP--------------ASPPMS---PSATPPPQ---APPPLAAPPLQV 737
Query: 405 PGDCTRAPPPSSESRPP 421
P +PP S + PP
Sbjct: 738 PPSPPASPPMSPSATPP 754
Score = 32.7 bits (73), Expect = 1.5
Identities = 38/136 (27%), Positives = 49/136 (36%), Gaps = 21/136 (15%)
Query: 288 LKRPSTRTPNANGTERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVA 347
L P TP++ T ++PP PP L P + T P+ +A
Sbjct: 576 LTTPPPETPSSIATPPPQAPPALASPP----LQGLPSPPLSPLATPPPQA-----PPXLA 626
Query: 348 LPGTKPTPIPP--PRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAP 405
LP + P PP P L A T S P A L SP +PP AP
Sbjct: 627 LPPLQAPPSPPASPPLSPLA----------TPSPQAPNALAVHLLQAPFSPPPSPPVQAP 676
Query: 406 GDCTRAPPPSSESRPP 421
+PP S + PP
Sbjct: 677 FSPPASPPVSPSATPP 692
Score = 32.0 bits (71), Expect = 2.6
Identities = 56/218 (25%), Positives = 77/218 (35%), Gaps = 25/218 (11%)
Query: 213 SSPADSKPPNLPPPHRPLSSDGVCPAS-LRQLCLINGVHSIKTRTPSELECSQTNGALCF 271
S + S+P + PP PL + PAS Q L V + +P + Q +L
Sbjct: 440 SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLS--SPLTIHPLQALSSLAS 497
Query: 272 INPLFLKVHSQDLSGGLKRPSTRTPNANGTERTRSPPPRPPPPAINSLHTSPRLARTETQ 331
+P Q L P T ++ ++PP P + +L P LA Q
Sbjct: 498 HSP-------QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL---PSLAPPPLQ 547
Query: 332 T-SMPETVNHNKHGNVALP---GTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAG-P 386
T S P T H + P P+P+ P + +S A P G P
Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607
Query: 387 ELELGTAGSPGGAPPEAAPGDCTRAP---PPSSESRPP 421
L SP PP AP P PPS + PP
Sbjct: 608 SPPL----SPLATPPPQAPPXLALPPLQAPPSPPASPP 641
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 47.0 bits (110), Expect = 8e-05
Identities = 50/211 (23%), Positives = 75/211 (35%), Gaps = 23/211 (10%)
Query: 280 HSQDLSGGLKRPSTRTPNANGTERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVN 339
H Q L+ K P+++ + P+ P A + T PR+ + + P
Sbjct: 241 HQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGR 300
Query: 340 HNKHGNVALPGTKPT-PIPPPRLKKQASFLEAEGGAKTLSGGR--------PGAGPELEL 390
A T P P P PR Q L + G+ +L GR P P+
Sbjct: 301 PTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSE 360
Query: 391 GTAGSPGGAPP-----EAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSSSDSLEFD 445
GT +P PP +A P PPSS PP RQ + + E
Sbjct: 361 GTP-APRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQ--------VENGGTEEVA 411
Query: 446 RSMPLFGYEADTNSSLEDYEGESDQETMAPP 476
+ P E+ + E+ E + ++E A P
Sbjct: 412 QPSPTASLESKPYNPFEEEEEDKEEEAPAAP 442
Score = 33.5 bits (75), Expect = 0.91
Identities = 63/264 (23%), Positives = 95/264 (35%), Gaps = 46/264 (17%)
Query: 196 KSEAQLEELAQMGLNFWSSPADSKPPNLPPPH---RPLSSDGVCPASLRQLCLINGVHSI 252
+S Q E L + + SS + + LP P P S+G PA + I V +
Sbjct: 322 RSSLQQENLVEQAGS--SSLVNGRLHELPVPKPRGTPKPSEGT-PAPRKDPPWITLVQAE 378
Query: 253 KTRTPSELECSQTNGALCFINPLFLKVHSQDL----SGGLKRPSTRTPNANGTERTRSP- 307
+ P+ L S + G SQD +GG + + +P A+ + +P
Sbjct: 379 PKKKPAPLPPSSSPGP-----------PSQDSRQVENGGTEEVAQPSPTASLESKPYNPF 427
Query: 308 -----PPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLK 362
PA SL TSP L E S P++++ P TP P+ K
Sbjct: 428 EEEEEDKEEEAPAAPSLATSPALGHPE---STPKSLH---------PWYGITPTSSPKTK 475
Query: 363 KQASFLEAEGGAKTLSGGR------PGAGPELELGTAGSPGGAPPEAAPGDCTRAPP-PS 415
K+ + L R P A P L + + A + P P
Sbjct: 476 KRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPK 535
Query: 416 SESRPPCHGGRQRLSDMSISTSSS 439
S S P H + +S+ST+SS
Sbjct: 536 SSSEPAVHAPGTPGNPVSLSTNSS 559
>gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]
Length = 1050
Score = 46.6 bits (109), Expect = 1e-04
Identities = 51/229 (22%), Positives = 110/229 (48%), Gaps = 32/229 (13%)
Query: 534 QDYVSFLQENKEC-------HVSSTDMLQT--IRQFM--TQVKNYLSQSSELDPPIESLI 582
++ SF + +EC H+ S + L T ++Q + + +K Q ++++ +
Sbjct: 154 RNIASFHRTFRECERKSLRHHIDSANALYTKCLQQLLRDSHLKMLAKQEAQMN------L 207
Query: 583 PEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHMADGSWKQLKENLQLVRQRNPQELGVF 642
+ +++ + ++ I K + G +EA D ++ ++ +LQ ++Q+ ++GV
Sbjct: 208 MKQAVEIYVHHEIYNLIFKYV-GTMEAS------EDAAFNKITRSLQDLQQK---DIGV- 256
Query: 643 APTPDF-VDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLI-YTVMENNSGRMYGADDFLP 700
P+F ++ + K + + K SP++K++ L +V +LI + + + ADD L
Sbjct: 257 --KPEFSFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSPSQRVNLETMCADDLLS 314
Query: 701 VLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIK 749
VL Y++ + ++ + Y+ SL E GY LTS A+ I+
Sbjct: 315 VLLYLLVKTEIPNWMANLSYIKNFRFSSLAKDELGYCLTSFEAAIEYIR 363
>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
sapiens]
Length = 678
Score = 46.6 bits (109), Expect = 1e-04
Identities = 51/169 (30%), Positives = 67/169 (39%), Gaps = 37/169 (21%)
Query: 296 PNANGTERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTP 355
P G+ PPP PPPPA P A + P G A PG + +
Sbjct: 85 PRRRGSPERARPPPPPPPPA---PPRPPPAAPSPPAAPGP-------RGGGASPGARRSD 134
Query: 356 IPPPRLKKQAS--------FLEAEGGAKTLSGG----RPGAGPELELGTAGSPGGA---P 400
L+K S L GA+ LS G P AGP L AGSP G+
Sbjct: 135 F----LQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRL--AGSPPGSGQWK 188
Query: 401 PEAAPGDCTRAPPPS------SESRPPCHGGRQRLSDMSISTSSSDSLE 443
P+ GD + PPPS + + PP + +S +TS++DS E
Sbjct: 189 PKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFE 237
>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo
sapiens]
Length = 650
Score = 46.6 bits (109), Expect = 1e-04
Identities = 51/169 (30%), Positives = 67/169 (39%), Gaps = 37/169 (21%)
Query: 296 PNANGTERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTP 355
P G+ PPP PPPPA P A + P G A PG + +
Sbjct: 85 PRRRGSPERARPPPPPPPPA---PPRPPPAAPSPPAAPGP-------RGGGASPGARRSD 134
Query: 356 IPPPRLKKQAS--------FLEAEGGAKTLSGG----RPGAGPELELGTAGSPGGA---P 400
L+K S L GA+ LS G P AGP L AGSP G+
Sbjct: 135 F----LQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRL--AGSPPGSGQWK 188
Query: 401 PEAAPGDCTRAPPPS------SESRPPCHGGRQRLSDMSISTSSSDSLE 443
P+ GD + PPPS + + PP + +S +TS++DS E
Sbjct: 189 PKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFE 237
>gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens]
Length = 631
Score = 46.2 bits (108), Expect = 1e-04
Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 15/98 (15%)
Query: 667 PEKKVMLLLRVCKLIYTVMENN---------------SGRMYGADDFLPVLTYVIAQCDM 711
P+KK+ ++R ++I E+ + GADD LP+L++V+ + +
Sbjct: 525 PQKKLECIVRTLRIICVCAEDYCPTPEATPQAGPPPIAAAAIGADDLLPILSFVVLRSGL 584
Query: 712 LELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIK 749
+L +E + E + L GE GY LTS ALS ++
Sbjct: 585 PQLVSECAALEEFIHEGYLIGEEGYCLTSLQSALSYVE 622
>gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo
sapiens]
Length = 1487
Score = 46.2 bits (108), Expect = 1e-04
Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 660 TMQKMYSPEKKVMLLLRVCKLIYTVME-NNSGRMYGADDFLPVLTYVIAQCDMLELDTEI 718
T+ +P KV +LR+C I ++ N + GADDF+PVL +V+ + + L + +
Sbjct: 1392 TISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTV 1451
Query: 719 EYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQ 755
+Y+ S L GE Y+ A+ IK + +
Sbjct: 1452 QYISSFY-ASCLSGEESYWWMQFTAAVEFIKTIDDRK 1487
>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
Length = 845
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/134 (28%), Positives = 46/134 (34%), Gaps = 14/134 (10%)
Query: 295 TPNANGTE----RTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPG 350
+P A GT T S PRPP P+ TS S T H G P
Sbjct: 464 SPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTS----------SGGGTGPHPPSGTTLRPP 513
Query: 351 TKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTR 410
T TP PP + S A G T +PG + G S P + G
Sbjct: 514 TSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQT 573
Query: 411 APPPSSESRPPCHG 424
P +S+ PP G
Sbjct: 574 PEPGTSQPMPPSMG 587
Score = 33.1 bits (74), Expect = 1.2
Identities = 31/118 (26%), Positives = 45/118 (38%), Gaps = 14/118 (11%)
Query: 344 GNVALPGTKPTP-IPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAP-- 400
G P T T +P P Q + GG +G P +G L T+ +PGG P
Sbjct: 468 GGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGG---TGPHPPSGTTLRPPTSSTPGGPPGA 524
Query: 401 -------PEAAPGDCTRAPPP-SSESRPPCHGGRQRLSDMSISTSSSDSLEFDRSMPL 450
P GD + P P +S+ PP G + S ++ + E S P+
Sbjct: 525 ENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPM 582
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 45.1 bits (105), Expect = 3e-04
Identities = 64/228 (28%), Positives = 83/228 (36%), Gaps = 37/228 (16%)
Query: 214 SPADSKPPNLPPPHRP-LSSDGVC--PASLRQLCLINGVHSIKTRTPSELECSQTNGALC 270
+PA KP N PP H SS G P SL S K T S +Q G
Sbjct: 637 APAPPKPGNPPPGHPGGQSSSGTSQHPPSL----------SPKPPTRSPSPPTQHTG--- 683
Query: 271 FINPLFLKVHSQDLSGGLKRPSTRTPNANGTERTRSPPPRPPPPAINSLHTSPRLARTET 330
P LS + S+ +P + PPP+PP A +HT P
Sbjct: 684 --QPPGQPSAPSQLSAPRRYSSSLSP----IQAPNHPPPQPPTQATPLMHTKPNSQGPPN 737
Query: 331 QTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELEL 390
++P H P PTP P L KQ L A +TL+GG PE
Sbjct: 738 PMALPS--EHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPA---PQTLAGG----NPETAQ 788
Query: 391 GTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSS 438
AG+ P P + PPP +PP G D S++ ++
Sbjct: 789 PHAGTLPRPRPVPKPRNRPSVPPP---PQPP---GVHSAGDSSLTNTA 830
Score = 30.4 bits (67), Expect = 7.7
Identities = 44/181 (24%), Positives = 58/181 (32%), Gaps = 43/181 (23%)
Query: 281 SQDLSGGLKRPSTRTPNANGTERTRSPPPRPPPPA-------------INSLHTSPRLAR 327
++ SGG PS+ G PP+P P I S P+ A
Sbjct: 549 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAA 608
Query: 328 TETQTSMPETVNHNKHG----NVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPG 383
Q SM + HN G + KP P PP +PG
Sbjct: 609 GSHQLSMGQP--HNAAGPSPHTLRRAVKKPAPAPP----------------------KPG 644
Query: 384 AGPELELGTAGSPGGA--PPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSSSDS 441
P G S G + PP +P TR+P P ++ G S +S S S
Sbjct: 645 NPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSS 704
Query: 442 L 442
L
Sbjct: 705 L 705
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 45.1 bits (105), Expect = 3e-04
Identities = 64/228 (28%), Positives = 83/228 (36%), Gaps = 37/228 (16%)
Query: 214 SPADSKPPNLPPPHRP-LSSDGVC--PASLRQLCLINGVHSIKTRTPSELECSQTNGALC 270
+PA KP N PP H SS G P SL S K T S +Q G
Sbjct: 559 APAPPKPGNPPPGHPGGQSSSGTSQHPPSL----------SPKPPTRSPSPPTQHTG--- 605
Query: 271 FINPLFLKVHSQDLSGGLKRPSTRTPNANGTERTRSPPPRPPPPAINSLHTSPRLARTET 330
P LS + S+ +P + PPP+PP A +HT P
Sbjct: 606 --QPPGQPSAPSQLSAPRRYSSSLSP----IQAPNHPPPQPPTQATPLMHTKPNSQGPPN 659
Query: 331 QTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELEL 390
++P H P PTP P L KQ L A +TL+GG PE
Sbjct: 660 PMALPS--EHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPA---PQTLAGG----NPETAQ 710
Query: 391 GTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSS 438
AG+ P P + PPP +PP G D S++ ++
Sbjct: 711 PHAGTLPRPRPVPKPRNRPSVPPP---PQPP---GVHSAGDSSLTNTA 752
>gi|221219026 pleckstrin homology-like domain, family B, member 1
isoform b [Homo sapiens]
Length = 1319
Score = 44.7 bits (104), Expect = 4e-04
Identities = 60/272 (22%), Positives = 94/272 (34%), Gaps = 49/272 (18%)
Query: 215 PADSKPPNLPPPHRPLSSDGVCPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINP 274
PA + P PP+ P+ ++ L+NG H+ +T T C+ + + I
Sbjct: 146 PAGGRAPG--PPYSPVPAESES--------LVNGNHTPQTATRGPSACASHSSLVSSIEK 195
Query: 275 LFLKVHS----QDLSGGLKRP---STRTPNANGTERTRSPPPRPPPPAINSLH--TSPRL 325
++ ++ K+P S +P ANG SPP P ++ S + TSP
Sbjct: 196 DLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAF 255
Query: 326 ARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAG 385
+ + S +H+ G PG P+ P R L+
Sbjct: 256 SPLSSPASSGSCASHSPSGQE--PGPSVPPLVPARSSSYHLALQ---------------- 297
Query: 386 PELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSSSDSLEFD 445
P + P A + R RPP G R L+D +T +++
Sbjct: 298 ----------PPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRAT 347
Query: 446 RSMPLFGYEADTNSSLEDY--EGESDQETMAP 475
S L G SL +Y G Q T P
Sbjct: 348 ESPRLGGQLPVVAISLSEYPASGALSQPTSIP 379
>gi|221219024 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 44.7 bits (104), Expect = 4e-04
Identities = 60/272 (22%), Positives = 94/272 (34%), Gaps = 49/272 (18%)
Query: 215 PADSKPPNLPPPHRPLSSDGVCPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINP 274
PA + P PP+ P+ ++ L+NG H+ +T T C+ + + I
Sbjct: 146 PAGGRAPG--PPYSPVPAESES--------LVNGNHTPQTATRGPSACASHSSLVSSIEK 195
Query: 275 LFLKVHS----QDLSGGLKRP---STRTPNANGTERTRSPPPRPPPPAINSLH--TSPRL 325
++ ++ K+P S +P ANG SPP P ++ S + TSP
Sbjct: 196 DLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAF 255
Query: 326 ARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAG 385
+ + S +H+ G PG P+ P R L+
Sbjct: 256 SPLSSPASSGSCASHSPSGQE--PGPSVPPLVPARSSSYHLALQ---------------- 297
Query: 386 PELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSSSDSLEFD 445
P + P A + R RPP G R L+D +T +++
Sbjct: 298 ----------PPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRAT 347
Query: 446 RSMPLFGYEADTNSSLEDY--EGESDQETMAP 475
S L G SL +Y G Q T P
Sbjct: 348 ESPRLGGQLPVVAISLSEYPASGALSQPTSIP 379
>gi|38424073 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 44.7 bits (104), Expect = 4e-04
Identities = 60/272 (22%), Positives = 94/272 (34%), Gaps = 49/272 (18%)
Query: 215 PADSKPPNLPPPHRPLSSDGVCPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINP 274
PA + P PP+ P+ ++ L+NG H+ +T T C+ + + I
Sbjct: 146 PAGGRAPG--PPYSPVPAESES--------LVNGNHTPQTATRGPSACASHSSLVSSIEK 195
Query: 275 LFLKVHS----QDLSGGLKRP---STRTPNANGTERTRSPPPRPPPPAINSLH--TSPRL 325
++ ++ K+P S +P ANG SPP P ++ S + TSP
Sbjct: 196 DLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAF 255
Query: 326 ARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAG 385
+ + S +H+ G PG P+ P R L+
Sbjct: 256 SPLSSPASSGSCASHSPSGQE--PGPSVPPLVPARSSSYHLALQ---------------- 297
Query: 386 PELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSSSDSLEFD 445
P + P A + R RPP G R L+D +T +++
Sbjct: 298 ----------PPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRAT 347
Query: 446 RSMPLFGYEADTNSSLEDY--EGESDQETMAP 475
S L G SL +Y G Q T P
Sbjct: 348 ESPRLGGQLPVVAISLSEYPASGALSQPTSIP 379
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 44.7 bits (104), Expect = 4e-04
Identities = 37/137 (27%), Positives = 45/137 (32%), Gaps = 4/137 (2%)
Query: 287 GLKRPSTRTPNANGTERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNV 346
G P P ++ + PPP+ PPP H P + Q P + V
Sbjct: 52 GQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVV 111
Query: 347 AL-PGTKP-TPIPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAA 404
A PG P PP GA SG PG P +P GAPP
Sbjct: 112 AQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSG--PGPTPTPPPAVTSAPPGAPPPTP 169
Query: 405 PGDCTRAPPPSSESRPP 421
P PP + PP
Sbjct: 170 PSSGVPTTPPQAGGPPP 186
Score = 43.5 bits (101), Expect = 9e-04
Identities = 37/140 (26%), Positives = 50/140 (35%), Gaps = 19/140 (13%)
Query: 287 GLKRPSTRTPNANGTERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNV 346
G+ R P G ++ PP PPPP P + + P H
Sbjct: 37 GMGLNQNRGPMGPGPGQSGPKPPIPPPP--------PHQQQQQPPPQQPPPQQPPPHQPP 88
Query: 347 ALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSP-----GGAPP 401
P PPP + + + A+G G PG G ++ P GAPP
Sbjct: 89 PHPQPHQQQQPPPPPQDSSKPVVAQG-----PGPAPGVGSAPPASSSAPPATPPTSGAPP 143
Query: 402 EAAPGDCTRAPPPSSESRPP 421
+ PG T PPP+ S PP
Sbjct: 144 GSGPGP-TPTPPPAVTSAPP 162
Score = 33.9 bits (76), Expect = 0.69
Identities = 39/136 (28%), Positives = 46/136 (33%), Gaps = 37/136 (27%)
Query: 295 TPNANGTERTRSPPPRP-PPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKP 353
TP +G P P P PPPA+ S +P A T S +P T P
Sbjct: 135 TPPTSGAPPGSGPGPTPTPPPAVTS---APPGAPPPTPPSS------------GVPTTPP 179
Query: 354 T---PIPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEA-APGDCT 409
P PPP + G PG GP+ G G GG P PG
Sbjct: 180 QAGGPPPPPA---------------AVPG--PGPGPKQGPGPGGPKGGKMPGGPKPGGGP 222
Query: 410 RAPPPSSESRPPCHGG 425
P +PP GG
Sbjct: 223 GLSTPGGHPKPPHRGG 238
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 44.3 bits (103), Expect = 5e-04
Identities = 40/162 (24%), Positives = 59/162 (36%), Gaps = 20/162 (12%)
Query: 292 STRTPNANGTERTRSPPPRPPPPAINSLHTSPR-----------LARTETQTSMPETVNH 340
+T T A E + PP PPPP + + + ++ S+ E +
Sbjct: 757 TTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKY 816
Query: 341 NKHGNVALPGTKPTPIP----PPRLKKQASFLEAEGGAKTLSGG-RPGAGPELELGTAGS 395
G A T+P P+P P A+ L A + G +P A + T+G
Sbjct: 817 CYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGG 876
Query: 396 PGG----APPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMS 433
P A E PG T PP S PP + L ++S
Sbjct: 877 PWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEIS 918
Score = 36.6 bits (83), Expect = 0.11
Identities = 45/169 (26%), Positives = 58/169 (34%), Gaps = 50/169 (29%)
Query: 307 PPPRPPPPAINSLHTSPRLART---------------ETQTSMPETVNHNKHGNVALPGT 351
PPP PPPP + L TSP T E + S P +H +LP
Sbjct: 256 PPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRH---SLPHP 312
Query: 352 KPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGD---- 407
P P P ++ G + + PG GP A S G P PG
Sbjct: 313 YPYPAP--------AYTAHPPGHRLVPAAPPGPGPRPP--GAESHGCLPATRPPGSDLRE 362
Query: 408 ---------------CTRAPPPSSESRPPCHGGRQRLSDMSISTSSSDS 441
T A P + SRPP G + S S+SSS++
Sbjct: 363 SRVQRSRMDSSVSPAATTACVPYAPSRPP---GLPGTTTSSSSSSSSNT 408
Score = 33.1 bits (74), Expect = 1.2
Identities = 27/108 (25%), Positives = 36/108 (33%), Gaps = 5/108 (4%)
Query: 323 PRLARTETQTSMPETVNHNKHG---NVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSG 379
P L T T +S + N G N +PG P + + ++
Sbjct: 391 PGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFL 450
Query: 380 GRPGAGPELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQ 427
G P A P L L P PP P PPP+ P C R+
Sbjct: 451 GAPAATPHLSLPPG--PSSPPPPPCPRLLRPPPPPAWLKGPACRAARE 496
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 44.3 bits (103), Expect = 5e-04
Identities = 35/115 (30%), Positives = 45/115 (39%), Gaps = 18/115 (15%)
Query: 315 AINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGA 374
A+ +L ++ L +Q P + N G G KP PPP K Q G
Sbjct: 9 ALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQ--------GP 60
Query: 375 KTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAP--PPSSESRPPCHGGRQ 427
G +P P G P G PP+ GD +R+P PP PP GG Q
Sbjct: 61 PPQGGNKPQGPP-----PPGKPQGPPPQ---GDKSRSPRSPPGKPQGPPPQGGNQ 107
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/168 (24%), Positives = 59/168 (35%), Gaps = 23/168 (13%)
Query: 281 SQDLSGGLKRPSTRTPNANGTERTRSPPPRP------PPPAINSLHTSPRLARTE----- 329
SQ+ S L + + P+ G + + PPP P PP N P + +
Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83
Query: 330 -TQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGA--GP 386
++ P + G G +P PPP K Q +GG + PG GP
Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNRPQGPPPPGKPQGP 141
Query: 387 ELE-------LGTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQ 427
+ G P G PP+ PPP PP GG++
Sbjct: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189
Score = 40.0 bits (92), Expect = 0.010
Identities = 41/149 (27%), Positives = 52/149 (34%), Gaps = 14/149 (9%)
Query: 290 RPSTRTPNANGTERTRSPPPRP--PPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVA 347
+P P + + RSPP +P PPP + P + Q P+ K
Sbjct: 137 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG---GKKPQGP 193
Query: 348 LPGTKPTPIPPPRLKKQASFLEAEG---GAKTLSGGRPGAGPELELGTAGSPGGAPPEAA 404
P KP PPP+ K S G G G +P P G P G PP+
Sbjct: 194 PPPGKPQG-PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP----PPGKPQGPPPQGG 248
Query: 405 PGDCTRAPPPSSESRPPCHGGRQRLSDMS 433
PPP PP GG + S S
Sbjct: 249 -NKPQGPPPPGKPQGPPAQGGSKSQSARS 276
Score = 39.3 bits (90), Expect = 0.017
Identities = 41/146 (28%), Positives = 49/146 (33%), Gaps = 30/146 (20%)
Query: 296 PNANGTERTRSPPPR-----PPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPG 350
P G R + PPP PPP S SPR + Q P+ G
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKS--RSPRSPPGKPQGPPPQG------------G 166
Query: 351 TKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGA--GPELE-------LGTAGSPGGAPP 401
+P PPP K Q +GG K PG GP + G P G PP
Sbjct: 167 NQPQGPPPPPGKPQGP--PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPP 224
Query: 402 EAAPGDCTRAPPPSSESRPPCHGGRQ 427
+ PPP PP GG +
Sbjct: 225 QGGNQPQGPPPPPGKPQGPPPQGGNK 250
Score = 39.3 bits (90), Expect = 0.017
Identities = 42/148 (28%), Positives = 56/148 (37%), Gaps = 31/148 (20%)
Query: 290 RPSTRTPNANGTERTRSPPPRP--PPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVA 347
+P P + + ++SPP +P PPP + P + Q P+
Sbjct: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG---------- 247
Query: 348 LPGTKPTPIPPPRLKKQASFLEAEGGAKTLSG----GRPGAGPELELGTAGSP----GG- 398
G KP PPP K Q A+GG+K+ S G+P P+ E P GG
Sbjct: 248 --GNKPQGPPPPG-KPQGP--PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGN 302
Query: 399 -----APPEAAPGDCTRAPPPSSESRPP 421
APP P R P SRPP
Sbjct: 303 PQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 44.3 bits (103), Expect = 5e-04
Identities = 37/124 (29%), Positives = 48/124 (38%), Gaps = 22/124 (17%)
Query: 304 TRSPPPRP--PPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRL 361
++ PPP P PPP + P L ++P TV +P + PT +PPP +
Sbjct: 524 SQMPPPLPTMPPPVL-----PPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGM 578
Query: 362 KKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPP----EAAPGDCTRAPPPSSE 417
S S G P P L +AG P PP AP PP SS
Sbjct: 579 PPSLS-----------SAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSA 627
Query: 418 SRPP 421
+ PP
Sbjct: 628 TPPP 631
Score = 34.3 bits (77), Expect = 0.53
Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 14/121 (11%)
Query: 307 PPP---RPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPT---PIPPPR 360
PPP RPPPP + R + ++S+P T V +P P P PPP
Sbjct: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVT-----RPPVPIPPPPPPPPLPPPPPV 1561
Query: 361 LKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRP 420
+K Q S +E E + G E L + A +AP PPP S P
Sbjct: 1562 IKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAP---VLPPPPVHSSIP 1618
Query: 421 P 421
P
Sbjct: 1619 P 1619
Score = 32.7 bits (73), Expect = 1.5
Identities = 35/131 (26%), Positives = 49/131 (37%), Gaps = 23/131 (17%)
Query: 307 PPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALP----GTKPTPIPPPRLK 362
PPP PPP+++S P L ++ P V + LP T P IPPP +
Sbjct: 587 PPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPV-------MPLPPLSSATPPPGIPPPGVP 639
Query: 363 K----QASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPP--------EAAPGDCTR 410
+ Q + + + S P L T S G APP A P +
Sbjct: 640 QGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVN 699
Query: 411 APPPSSESRPP 421
+ P S+S P
Sbjct: 700 SKAPLSKSALP 710
Score = 31.2 bits (69), Expect = 4.5
Identities = 50/223 (22%), Positives = 80/223 (35%), Gaps = 49/223 (21%)
Query: 307 PPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVAL--------PGTKPTPIPP 358
PPP PPPP P L+ + Q + ++H + G L P + P P P
Sbjct: 104 PPPMPPPP-------GPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVP-PG 155
Query: 359 PRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAPPPSSES 418
+ S++ P P T+ P P + +P +++PP S
Sbjct: 156 SYMPPSQSYMPP-----------PQPPPSYYPPTSSQPYLPPAQPSP---SQSPPSQSYL 201
Query: 419 RPPCHGGRQRLSDMSISTSSSDSLEFDRSMPLFGYEADTNSSLEDYEGESDQETMAPPIK 478
P S S S+SS L +S + S +G S + +APP
Sbjct: 202 AP-------TPSYSSSSSSSQSYLSHSQSY----LPSSQASPSRPSQGHSKSQLLAPPPP 250
Query: 479 SKKKRSSSFVLPKLVKS--------QLQKVSGVFSSFMTPEKR 513
S + + V + ++S Q Q S MTP+++
Sbjct: 251 SAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQ 293
Score = 30.4 bits (67), Expect = 7.7
Identities = 24/71 (33%), Positives = 28/71 (39%), Gaps = 12/71 (16%)
Query: 278 KVHSQDLSGGLKRPST---------RTPNANGTERTRSPPPRPPPPAINSLHTSPRLART 328
K HS GG RPS P+ G ER P R P PA + H P R
Sbjct: 1751 KDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPSLSHQPPPAPRV 1810
Query: 329 ETQTSMPETVN 339
E + PE+ N
Sbjct: 1811 EKK---PESKN 1818
>gi|71979663 growth factor receptor-bound protein 14 [Homo sapiens]
Length = 540
Score = 43.5 bits (101), Expect = 9e-04
Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 69 KTCAR--DSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVL--QAQPPGIFLVHKS 124
K C R G + S++ S + +H W +S +EA ++ Q G+FLV S
Sbjct: 409 KGCLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDS 468
Query: 125 TKMQKKVLSLRLPCEFGAPLKEFAI----KESTYTFSLEGSGISFADLFRLIAFYCISRD 180
K + L G +K F I + +L+ F DL +L+ FY +++
Sbjct: 469 QSNPKTFV---LSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKG 525
Query: 181 VLPFTLK 187
VLP LK
Sbjct: 526 VLPCKLK 532
>gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
preproprotein [Homo sapiens]
Length = 178
Score = 43.1 bits (100), Expect = 0.001
Identities = 34/114 (29%), Positives = 45/114 (39%), Gaps = 18/114 (15%)
Query: 315 AINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGA 374
A+ +L ++ L +Q P + N G G KP PPP K Q G
Sbjct: 9 ALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQ--------GP 60
Query: 375 KTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAP--PPSSESRPPCHGGR 426
G +P P G P G PP+ GD +R+P PP PP GG+
Sbjct: 61 PPQGGNKPQGPPP-----PGKPQGPPPQ---GDKSRSPRSPPGKPQGPPPQGGK 106
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/159 (30%), Positives = 66/159 (41%), Gaps = 23/159 (14%)
Query: 281 SQDLSGGLKRPSTRTPNANGTERTRSPPPRP-----PPPAINSLHTSPRLARTETQTSMP 335
SQ+ S L + + P+ G + + PPP P PPP + P + Q P
Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPP 82
Query: 336 ETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSG----GRPGAGPELELG 391
+ +K + P KP PP K Q A+GG+K+ S G+P P+ E
Sbjct: 83 Q---GDKSRSPRSPPGKPQGPPPQGGKPQGP--PAQGGSKSQSARSPPGKPQGPPQQE-- 135
Query: 392 TAGSPGGAPPEAAPG-DCTRAPP---PSSESRPPCHGGR 426
+P G PP A +APP P RPP GGR
Sbjct: 136 -GNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP-QGGR 172
>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
preproprotein [Homo sapiens]
Length = 198
Score = 43.1 bits (100), Expect = 0.001
Identities = 34/114 (29%), Positives = 45/114 (39%), Gaps = 18/114 (15%)
Query: 315 AINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGA 374
A+ +L ++ L +Q P + N G G KP PPP K Q G
Sbjct: 9 ALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQ--------GP 60
Query: 375 KTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAP--PPSSESRPPCHGGR 426
G +P P G P G PP+ GD +R+P PP PP GG+
Sbjct: 61 PPQGGNKPQGPPP-----PGKPQGPPPQ---GDKSRSPRSPPGKPQGPPPQGGK 106
Score = 41.2 bits (95), Expect = 0.004
Identities = 44/142 (30%), Positives = 52/142 (36%), Gaps = 21/142 (14%)
Query: 296 PNANGTERTRSPPPRPP--PPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKP 353
P G + PPP P PP SPR + Q P+ G G KP
Sbjct: 61 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ--GGKPQGPPPQGGNKP 118
Query: 354 TPIPPPRLKKQASFLEAEGGAKTLSG----GRPGAGPELELGTAGSP----GG------A 399
PPP K Q A+GG+K+ S G+P P+ E P GG A
Sbjct: 119 QGPPPPG-KPQGP--PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 175
Query: 400 PPEAAPGDCTRAPPPSSESRPP 421
PP P R P SRPP
Sbjct: 176 PPAGQPQGPPRPPQGGRPSRPP 197
Score = 40.0 bits (92), Expect = 0.010
Identities = 49/176 (27%), Positives = 66/176 (37%), Gaps = 37/176 (21%)
Query: 281 SQDLSGGLKRPSTRTPNANGTERTRSPPPRP----------------PPPAINSLHTSPR 324
SQ+ S L + + P+ G + + PPP P PPP P+
Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83
Query: 325 LARTETQTSM------PETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLS 378
++ + S P G G KP PPP K Q A+GG+K+ S
Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPG-KPQGP--PAQGGSKSQS 140
Query: 379 G----GRPGAGPELELGTAGSPGGAPPEAAPG-DCTRAPP---PSSESRPPCHGGR 426
G+P P+ E +P G PP A +APP P RPP GGR
Sbjct: 141 ARSPPGKPQGPPQQE---GNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP-QGGR 192
>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
sapiens]
Length = 1059
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/140 (27%), Positives = 57/140 (40%), Gaps = 28/140 (20%)
Query: 307 PPPRPPPPAINSLHTS--------PRLARTETQTSMPETVNHNKHGNVALPGTKPTP--- 355
PPP+PPPP + S P + + + +S + + + + + KP P
Sbjct: 68 PPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLP 127
Query: 356 ----IPPPRLKKQASFLEAEGGAKTLSG----------GRPGAGPELELGTAGSPGGAP- 400
PPP L A+F + G LSG G P +GP + G G+P GAP
Sbjct: 128 PAFGAPPPPLF-DAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVTPG-LGAPAGAPG 185
Query: 401 PEAAPGDCTRAPPPSSESRP 420
P AP PP ++ P
Sbjct: 186 PLPAPSQTPPGPPAAAACDP 205
>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
sapiens]
Length = 1059
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/140 (27%), Positives = 57/140 (40%), Gaps = 28/140 (20%)
Query: 307 PPPRPPPPAINSLHTS--------PRLARTETQTSMPETVNHNKHGNVALPGTKPTP--- 355
PPP+PPPP + S P + + + +S + + + + + KP P
Sbjct: 68 PPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLP 127
Query: 356 ----IPPPRLKKQASFLEAEGGAKTLSG----------GRPGAGPELELGTAGSPGGAP- 400
PPP L A+F + G LSG G P +GP + G G+P GAP
Sbjct: 128 PAFGAPPPPLF-DAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVTPG-LGAPAGAPG 185
Query: 401 PEAAPGDCTRAPPPSSESRP 420
P AP PP ++ P
Sbjct: 186 PLPAPSQTPPGPPAAAACDP 205
>gi|38373682 pleckstrin homology domain containing family G member 5
isoform a [Homo sapiens]
Length = 1006
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/134 (26%), Positives = 54/134 (40%), Gaps = 9/134 (6%)
Query: 296 PNANGTERTRSPPPRPP---PPAINSLHTSPRLARTETQTSMPETV-NHNKHGNVALPGT 351
P A + R SPPP P + L P L +++++ S+ + + HG + P
Sbjct: 841 PRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSR 900
Query: 352 KPTP----IPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGD 407
+ +P P ++ Q S EA PG+GP L AG P G+ + GD
Sbjct: 901 SLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRKRC-GD 959
Query: 408 CTRAPPPSSESRPP 421
P + PP
Sbjct: 960 LPSGASPRVQPEPP 973
>gi|111154084 pleckstrin homology domain containing family G member 5
isoform b [Homo sapiens]
Length = 1083
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/134 (26%), Positives = 54/134 (40%), Gaps = 9/134 (6%)
Query: 296 PNANGTERTRSPPPRPP---PPAINSLHTSPRLARTETQTSMPETV-NHNKHGNVALPGT 351
P A + R SPPP P + L P L +++++ S+ + + HG + P
Sbjct: 918 PRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSR 977
Query: 352 KPTP----IPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGD 407
+ +P P ++ Q S EA PG+GP L AG P G+ + GD
Sbjct: 978 SLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRKRC-GD 1036
Query: 408 CTRAPPPSSESRPP 421
P + PP
Sbjct: 1037 LPSGASPRVQPEPP 1050
>gi|111154088 pleckstrin homology domain containing family G member
5 isoform a [Homo sapiens]
Length = 1006
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/134 (26%), Positives = 54/134 (40%), Gaps = 9/134 (6%)
Query: 296 PNANGTERTRSPPPRPP---PPAINSLHTSPRLARTETQTSMPETV-NHNKHGNVALPGT 351
P A + R SPPP P + L P L +++++ S+ + + HG + P
Sbjct: 841 PRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSR 900
Query: 352 KPTP----IPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGD 407
+ +P P ++ Q S EA PG+GP L AG P G+ + GD
Sbjct: 901 SLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRKRC-GD 959
Query: 408 CTRAPPPSSESRPP 421
P + PP
Sbjct: 960 LPSGASPRVQPEPP 973
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,507,687
Number of Sequences: 37866
Number of extensions: 2110409
Number of successful extensions: 18330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 678
Number of HSP's that attempted gapping in prelim test: 13885
Number of HSP's gapped (non-prelim): 4474
length of query: 895
length of database: 18,247,518
effective HSP length: 111
effective length of query: 784
effective length of database: 14,044,392
effective search space: 11010803328
effective search space used: 11010803328
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.