Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 18379349
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
(393 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18379349 vesicle amine transport protein 1 [Homo sapiens] 788 0.0
gi|24308257 vesicle amine transport protein 1 homolog (T. califo... 316 2e-86
gi|194239674 crystallin, zeta isoform a [Homo sapiens] 159 4e-39
gi|13236495 crystallin, zeta isoform a [Homo sapiens] 159 4e-39
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens] 140 2e-33
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens] 140 2e-33
gi|194239676 crystallin, zeta isoform b [Homo sapiens] 130 2e-30
gi|28557745 zinc binding alcohol dehydrogenase domain containing... 113 3e-25
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a... 96 4e-20
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b... 88 2e-17
gi|197927207 crystallin, zeta isoform c [Homo sapiens] 79 9e-15
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa... 72 7e-13
gi|41872631 fatty acid synthase [Homo sapiens] 65 1e-10
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens] 52 7e-07
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens] 52 7e-07
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens] 52 7e-07
gi|156627571 sorbitol dehydrogenase [Homo sapiens] 50 5e-06
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa... 49 6e-06
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa... 49 8e-06
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa... 48 1e-05
gi|90669511 crystallin, zeta-like 1 [Homo sapiens] 48 2e-05
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s... 42 0.001
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap... 42 0.001
gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens] 39 0.008
gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens] 39 0.008
gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit ... 35 0.15
gi|239741585 PREDICTED: hypothetical protein XP_002342243 [Homo ... 34 0.20
gi|226246682 prostaglandin reductase 2 [Homo sapiens] 34 0.26
gi|226246680 prostaglandin reductase 2 [Homo sapiens] 34 0.26
gi|22748929 prostaglandin reductase 2 [Homo sapiens] 34 0.26
>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
Length = 393
Score = 788 bits (2035), Expect = 0.0
Identities = 393/393 (100%), Positives = 393/393 (100%)
Query: 1 MSDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYD 60
MSDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYD
Sbjct: 1 MSDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYD 60
Query: 61 KVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIA 120
KVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIA
Sbjct: 61 KVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIA 120
Query: 121 VGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVL 180
VGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVL
Sbjct: 121 VGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVL 180
Query: 181 FDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDY 240
FDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDY
Sbjct: 181 FDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDY 240
Query: 241 HTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMA 300
HTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMA
Sbjct: 241 HTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMA 300
Query: 301 LARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDS 360
LARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDS
Sbjct: 301 LARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDS 360
Query: 361 VWPFEKVADAMKQMQEKKNVGKVLLVPGPEKEN 393
VWPFEKVADAMKQMQEKKNVGKVLLVPGPEKEN
Sbjct: 361 VWPFEKVADAMKQMQEKKNVGKVLLVPGPEKEN 393
>gi|24308257 vesicle amine transport protein 1 homolog (T.
californica)-like [Homo sapiens]
Length = 419
Score = 316 bits (810), Expect = 2e-86
Identities = 163/365 (44%), Positives = 234/365 (64%), Gaps = 8/365 (2%)
Query: 24 EAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRL 83
EA +P +G+ + + R +VL GFGG +K++L + A P P G+L +R+
Sbjct: 19 EAGKEPAEGGGGDGSHRLGDAQEM-RAVVLAGFGGLNKLRLFRK--AMPEPQDGELKIRV 75
Query: 84 RACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMW 143
+ACGLNF DLM RQG D P P+ PG E +G+V A+G+ V + GDRVM W
Sbjct: 76 KACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAW 135
Query: 144 QEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGM 203
E V P + IP+ M+F EAAA +N++TAY++LF+ NL+ G SVLVH A GGVG
Sbjct: 136 AEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSAGGGVGQ 195
Query: 204 AAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDP 263
A QLC TV NVTVFGTAS KHEA+K++ VTH D DYV E+K+IS +GVDIV+D
Sbjct: 196 AVAQLCSTVPNVTVFGTASTFKHEAIKDS-VTHLFD-RNADYVQEVKRISAEGVDIVLDC 253
Query: 264 LGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMALARTWWNQFSVTALQLLQANRAV 323
L G +T KG +LLKP+G + YG +N++TG ++ + A++WW V ++L + N+ +
Sbjct: 254 LCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVI 313
Query: 324 CGF---HLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNV 380
GF +L + G L+ GVV +L+ LYNQ IKP +DS+W E+V +AM+++ ++ N+
Sbjct: 314 AGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKEAMQRIHDRGNI 373
Query: 381 GKVLL 385
GK++L
Sbjct: 374 GKLIL 378
>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 159 bits (402), Expect = 4e-39
Identities = 111/349 (31%), Positives = 176/349 (50%), Gaps = 26/349 (7%)
Query: 42 AASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYD 101
A L+R + + FGG + +KL+S A P P Q+ +++ ACG+N + R G Y
Sbjct: 2 ATGQKLMRAVRVFEFGGPEVLKLRS-DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60
Query: 102 RLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNR-SGMWQEEVTVPSVQTFLIPEA 160
R P LP TPG + AGV+ AVG+ S K GDRV + SG + E + +PE
Sbjct: 61 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 120
Query: 161 MTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT 220
+ F++ AA+ + Y TAY L ++ G SVLVH A+GGVG+AA Q+ R + + GT
Sbjct: 121 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAY-GLKILGT 179
Query: 221 ASASK-HEALKENGVTHPIDYHTTDYVDEIKK-ISPKGVDIVMDPLGGSDTAKGYNLLKP 278
A + + + +NG ++ +Y+D+IKK + KG+DI+++ L + +K +LL
Sbjct: 180 AGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSH 239
Query: 279 MGKVVTYGMANLLTGPKRNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELV 338
G+V+ G + R+ MA + S+ + L + + E
Sbjct: 240 GGRVIVVGSRGTIEINPRDTMA------KESSIIGVTLFSSTK--------------EEF 279
Query: 339 SGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKN-VGKVLLV 386
A L A G +KP I S +P EKVA+A + + GK++L+
Sbjct: 280 QQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILL 328
>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 159 bits (402), Expect = 4e-39
Identities = 111/349 (31%), Positives = 176/349 (50%), Gaps = 26/349 (7%)
Query: 42 AASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYD 101
A L+R + + FGG + +KL+S A P P Q+ +++ ACG+N + R G Y
Sbjct: 2 ATGQKLMRAVRVFEFGGPEVLKLRS-DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60
Query: 102 RLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNR-SGMWQEEVTVPSVQTFLIPEA 160
R P LP TPG + AGV+ AVG+ S K GDRV + SG + E + +PE
Sbjct: 61 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 120
Query: 161 MTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT 220
+ F++ AA+ + Y TAY L ++ G SVLVH A+GGVG+AA Q+ R + + GT
Sbjct: 121 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAY-GLKILGT 179
Query: 221 ASASK-HEALKENGVTHPIDYHTTDYVDEIKK-ISPKGVDIVMDPLGGSDTAKGYNLLKP 278
A + + + +NG ++ +Y+D+IKK + KG+DI+++ L + +K +LL
Sbjct: 180 AGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSH 239
Query: 279 MGKVVTYGMANLLTGPKRNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELV 338
G+V+ G + R+ MA + S+ + L + + E
Sbjct: 240 GGRVIVVGSRGTIEINPRDTMA------KESSIIGVTLFSSTK--------------EEF 279
Query: 339 SGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKN-VGKVLLV 386
A L A G +KP I S +P EKVA+A + + GK++L+
Sbjct: 280 QQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILL 328
>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 140 bits (353), Expect = 2e-33
Identities = 100/325 (30%), Positives = 158/325 (48%), Gaps = 14/325 (4%)
Query: 64 LQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGE 123
L + A P+PG G++ L++ A LN ADLM RQG YD P G+E +G V +G
Sbjct: 15 LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74
Query: 124 GVSDR-KAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFD 182
G K GD M L G + VTVP IPE +T +AAA+ ++TA+ +L
Sbjct: 75 GCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHL 134
Query: 183 FGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDYHT 242
GN+Q G VL+H GVG AA+QL R + + S K + ++ G +Y
Sbjct: 135 VGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK 194
Query: 243 TDYVDEIKKISP-KGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMAL 301
D+ + K + GV++++D +GGS K N L G+ V YG L+ G N
Sbjct: 195 EDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG---LMGGGDINGPLF 251
Query: 302 ARTWWNQFS-VTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDS 360
++ + + S +T+L + N+ Y V + + + + P +D
Sbjct: 252 SKLLFKRGSLITSLLRSRDNK--------YKQMLVNAFTEQILPHFSTEGPQRLLPVLDR 303
Query: 361 VWPFEKVADAMKQMQEKKNVGKVLL 385
++P ++ +A K M+ KN+GK++L
Sbjct: 304 IYPVTEIQEAHKYMEANKNIGKIVL 328
>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 140 bits (353), Expect = 2e-33
Identities = 100/325 (30%), Positives = 158/325 (48%), Gaps = 14/325 (4%)
Query: 64 LQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGE 123
L + A P+PG G++ L++ A LN ADLM RQG YD P G+E +G V +G
Sbjct: 15 LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74
Query: 124 GVSDR-KAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFD 182
G K GD M L G + VTVP IPE +T +AAA+ ++TA+ +L
Sbjct: 75 GCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHL 134
Query: 183 FGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDYHT 242
GN+Q G VL+H GVG AA+QL R + + S K + ++ G +Y
Sbjct: 135 VGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK 194
Query: 243 TDYVDEIKKISP-KGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMAL 301
D+ + K + GV++++D +GGS K N L G+ V YG L+ G N
Sbjct: 195 EDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG---LMGGGDINGPLF 251
Query: 302 ARTWWNQFS-VTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDS 360
++ + + S +T+L + N+ Y V + + + + P +D
Sbjct: 252 SKLLFKRGSLITSLLRSRDNK--------YKQMLVNAFTEQILPHFSTEGPQRLLPVLDR 303
Query: 361 VWPFEKVADAMKQMQEKKNVGKVLL 385
++P ++ +A K M+ KN+GK++L
Sbjct: 304 IYPVTEIQEAHKYMEANKNIGKIVL 328
>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
Length = 295
Score = 130 bits (327), Expect = 2e-30
Identities = 77/217 (35%), Positives = 119/217 (54%), Gaps = 4/217 (1%)
Query: 42 AASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYD 101
A L+R + + FGG + +KL+S A P P Q+ +++ ACG+N + R G Y
Sbjct: 2 ATGQKLMRAVRVFEFGGPEVLKLRS-DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60
Query: 102 RLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNR-SGMWQEEVTVPSVQTFLIPEA 160
R P LP TPG + AGV+ AVG+ S K GDRV + SG + E + +PE
Sbjct: 61 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 120
Query: 161 MTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT 220
+ F++ AA+ + Y TAY L ++ G SVLVH A+GGVG+AA Q+ R + + GT
Sbjct: 121 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAY-GLKILGT 179
Query: 221 ASASK-HEALKENGVTHPIDYHTTDYVDEIKKISPKG 256
A + + + +NG ++ +Y+D+IK + +G
Sbjct: 180 AGTEEGQKIVLQNGAHEVFNHREVNYIDKIKVVGSRG 216
>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
[Homo sapiens]
Length = 377
Score = 113 bits (282), Expect = 3e-25
Identities = 100/354 (28%), Positives = 155/354 (43%), Gaps = 23/354 (6%)
Query: 42 AASPPLLRCLVLTGFG-GYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLY 100
+A P ++ LV+T + + SR P PG G L +R R G+N +D+ G Y
Sbjct: 27 SAIPQAMQKLVVTRLSPNFREAVTLSRDCPVPLPGDGDLLVRNRFVGVNASDINYSAGRY 86
Query: 101 DRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEA 160
D P G EG G V+A+G S R + + G + E VP+ +P
Sbjct: 87 DPSVKPPFDIGFEGIGEVVALGLSASARYTVGQAVAYMAPGSFAEYTVVPASIATPVPSV 146
Query: 161 MTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT 220
E LLV+ TAY+ L + G L G VLV AAGG G A+QL + + V GT
Sbjct: 147 KP--EYLTLLVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAK-CHVIGT 203
Query: 221 ASASKHEA-LKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPM 279
S+ + A LK G PI+Y T +K+ P+GVD+V + +GG+ + L
Sbjct: 204 CSSDEKSAFLKSLGCDRPINYKTEPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATK 263
Query: 280 GKVVTYGMANLLTGPKRNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVS 339
G+++ G + P A T +LL+ + +V GF +L+ +
Sbjct: 264 GRLIVIGFISGYQTPTGLSPVKAGT-------LPAKLLKKSASVQGF---FLNHYLSKYQ 313
Query: 340 GVVARLLALYNQGHIKPHID--------SVWPFEKVADAMKQMQEKKNVGKVLL 385
++ LL + G + +D E + A+ M KN GK+++
Sbjct: 314 AAMSHLLEMCVSGDLVCEVDLGDLSPEGRFTGLESIFRAVNYMYMGKNTGKIVV 367
>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
[Homo sapiens]
Length = 373
Score = 96.3 bits (238), Expect = 4e-20
Identities = 84/274 (30%), Positives = 124/274 (45%), Gaps = 23/274 (8%)
Query: 26 ASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRA 85
AS PAAS + +A+A P +R LV G KV ++ + A + +++ A
Sbjct: 23 ASGCHGPAAS--SYSASAEPARVRALVYGHHGDPAKV-VELKNLELAAVRGSDVRVKMLA 79
Query: 86 CGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRS-GMWQ 144
+N +D+ QG Y LP LP G EG V+AVG V+ K GD V+ N G W+
Sbjct: 80 APINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWR 139
Query: 145 EEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMA 204
E +P + + AA L VN TAY +L DF LQPG SV+ + + GVG A
Sbjct: 140 TEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQA 199
Query: 205 AVQLC-----RTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGV-- 257
+Q+ RT+ NV + LK G H I +E+++ K
Sbjct: 200 VIQIAAALGLRTI-NVVRDRPDIQKLSDRLKSLGAEHVIT------EEELRRPEMKNFFK 252
Query: 258 -----DIVMDPLGGSDTAKGYNLLKPMGKVVTYG 286
+ ++ +GG + + L G +VTYG
Sbjct: 253 DMPQPRLALNCVGGKSSTELLRQLARGGTMVTYG 286
>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
[Homo sapiens]
Length = 297
Score = 87.8 bits (216), Expect = 2e-17
Identities = 68/215 (31%), Positives = 97/215 (45%), Gaps = 20/215 (9%)
Query: 85 ACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRS-GMW 143
A +N +D+ QG Y LP LP G EG V+AVG V+ K GD V+ N G W
Sbjct: 3 AAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTW 62
Query: 144 QEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGM 203
+ E +P + + AA L VN TAY +L DF LQPG SV+ + + GVG
Sbjct: 63 RTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQ 122
Query: 204 AAVQLC-----RTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGV- 257
A +Q+ RT+ NV + LK G H I +E+++ K
Sbjct: 123 AVIQIAAALGLRTI-NVVRDRPDIQKLSDRLKSLGAEHVIT------EEELRRPEMKNFF 175
Query: 258 ------DIVMDPLGGSDTAKGYNLLKPMGKVVTYG 286
+ ++ +GG + + L G +VTYG
Sbjct: 176 KDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYG 210
>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
Length = 192
Score = 78.6 bits (192), Expect = 9e-15
Identities = 61/212 (28%), Positives = 102/212 (48%), Gaps = 24/212 (11%)
Query: 178 MVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASK-HEALKENGVTH 236
M L ++ G SVLVH A+GGVG+AA Q+ R + + GTA + + + +NG
Sbjct: 1 MHLLSSACVKAGESVLVHGASGGVGLAACQIARAY-GLKILGTAGTEEGQKIVLQNGAHE 59
Query: 237 PIDYHTTDYVDEIKK-ISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPK 295
++ +Y+D+IKK + KG+DI+++ L + +K +LL G+V+ G +
Sbjct: 60 VFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINP 119
Query: 296 RNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIK 355
R+ MA + S+ + L + + E A L A G +K
Sbjct: 120 RDTMA------KESSIIGVTLFSSTK--------------EEFQQYAAALQAGMEIGWLK 159
Query: 356 PHIDSVWPFEKVADAMKQMQEKKN-VGKVLLV 386
P I S +P EKVA+A + + GK++L+
Sbjct: 160 PVIGSQYPLEKVAEAHENIIHGSGATGKMILL 191
>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
sapiens]
Length = 396
Score = 72.4 bits (176), Expect = 7e-13
Identities = 89/358 (24%), Positives = 153/358 (42%), Gaps = 35/358 (9%)
Query: 52 VLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQG-----LYDRLPPL 106
V+ +G + ++ P P ++ +++ A +N D+ R G L + PL
Sbjct: 47 VIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPL 106
Query: 107 ---------PVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLN---RSGMWQEEVTVPSVQT 154
P+T G + +GVV+ G V K GD V + G E V V +
Sbjct: 107 HVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEV 166
Query: 155 FLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQ----PGHSVLVHMAAGGVGMAAVQLCR 210
P+++T +AA+L +TA+ + G L G VL+ A+GGVG A+Q+ +
Sbjct: 167 SHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMK 226
Query: 211 TVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTA 270
+ V S E +++ G IDY + +++K + P D ++D +GGS
Sbjct: 227 AWD-AHVTAVCSQDASELVRKLGADDVIDYKSGSVEEQLKSLKP--FDFILDNVGGSTET 283
Query: 271 KGYNLLKPMGKVVTYGMANLLTGPKRNLMALA-RTWWNQFSVTALQLLQANRAVCGFHLG 329
+ LK TY L+T N+ L Q VT ++A+ F G
Sbjct: 284 WAPDFLKKWSG-ATY--VTLVTPFLLNMDRLGIADGMLQTGVTV-----GSKALKHFWKG 335
Query: 330 -YLDGEVELVSG-VVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLL 385
+ + SG + + L + G I+P I+ +PF KV +A +++ GK ++
Sbjct: 336 VHYRWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 393
>gi|41872631 fatty acid synthase [Homo sapiens]
Length = 2511
Score = 65.1 bits (157), Expect = 1e-10
Identities = 87/332 (26%), Positives = 137/332 (41%), Gaps = 42/332 (12%)
Query: 67 RPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVS 126
R A P PG T+ + LNF D+M G +L P + PG + +G S
Sbjct: 1552 RHAQPTCPGAQLCTVYYAS--LNFRDIMLATG---KLSPDAI-PG-KWTSQDSLLGMEFS 1604
Query: 127 DRKA-GDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGN 185
R A G RVM L + V + + +P T EEAA++ V Y TAY L G
Sbjct: 1605 GRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGR 1664
Query: 186 LQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEA--------LKENGVTHP 237
++PG ++L+H +GGVG AA+ + ++ VF T +++ A L +
Sbjct: 1665 VRPGETLLIHSGSGGVGQAAIAIALSL-GCRVFTTVGSAEKRAYLQARFPQLDSTSFANS 1723
Query: 238 IDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRN 297
D +V + KGVD+V++ L L G+ + G +L
Sbjct: 1724 RDTSFEQHV--LWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLG 1781
Query: 298 LMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSG----VVARLLALYNQGH 353
+ + +VT FH LD S V A + A G
Sbjct: 1782 MAIFLK------NVT-------------FHGVLLDAFFNESSADWREVWALVQAGIRDGV 1822
Query: 354 IKPHIDSVWPFEKVADAMKQMQEKKNVGKVLL 385
++P +V+ +V DA + M + K++GKV++
Sbjct: 1823 VRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVV 1854
>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 52.4 bits (124), Expect = 7e-07
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Query: 174 ITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENG 233
+TAY L + ++ G +V+V+ AAG VG Q+ + V S K L++ G
Sbjct: 127 LTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLG 186
Query: 234 VTHPIDYHTTDYVDE-IKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLL- 291
+Y T + ++E +KK SP G D D +GG + +K G++ G +
Sbjct: 187 FDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYN 246
Query: 292 -TGP 294
TGP
Sbjct: 247 RTGP 250
>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 52.4 bits (124), Expect = 7e-07
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Query: 174 ITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENG 233
+TAY L + ++ G +V+V+ AAG VG Q+ + V S K L++ G
Sbjct: 127 LTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLG 186
Query: 234 VTHPIDYHTTDYVDE-IKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLL- 291
+Y T + ++E +KK SP G D D +GG + +K G++ G +
Sbjct: 187 FDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYN 246
Query: 292 -TGP 294
TGP
Sbjct: 247 RTGP 250
>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
Length = 301
Score = 52.4 bits (124), Expect = 7e-07
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Query: 174 ITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENG 233
+TAY L + ++ G +V+V+ AAG VG Q+ + V S K L++ G
Sbjct: 127 LTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLG 186
Query: 234 VTHPIDYHTTDYVDE-IKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLL- 291
+Y T + ++E +KK SP G D D +GG + +K G++ G +
Sbjct: 187 FDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYN 246
Query: 292 -TGP 294
TGP
Sbjct: 247 RTGP 250
>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
Length = 357
Score = 49.7 bits (117), Expect = 5e-06
Identities = 66/250 (26%), Positives = 106/250 (42%), Gaps = 52/250 (20%)
Query: 41 AAASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADL----MAR 96
AAA+ P LV+ G G ++L++ P P PGP ++ LR+ + G+ +D+ R
Sbjct: 2 AAAAKPNNLSLVVHGPGD---LRLENYPI--PEPGPNEVLLRMHSVGICGSDVHYWEYGR 56
Query: 97 QGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEE---------- 146
G + + P+ G E +G V VG V K GDRV + + +E
Sbjct: 57 IGNF--IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS 114
Query: 147 ------VTVP------------SVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQP 188
T P + + +P+ +TFEE A L+ ++ + G +
Sbjct: 115 PSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGA--LIEPLSVGIHACRRGGVTL 172
Query: 189 GHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT-ASASKHEALKENGVTHPIDYHTTDYVD 247
GH VLV AG +GM + + + + V T SA++ KE G D V
Sbjct: 173 GHKVLV-CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIG---------ADLVL 222
Query: 248 EIKKISPKGV 257
+I K SP+ +
Sbjct: 223 QISKESPQEI 232
>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
sapiens]
Length = 375
Score = 49.3 bits (116), Expect = 6e-06
Identities = 80/339 (23%), Positives = 123/339 (36%), Gaps = 83/339 (24%)
Query: 105 PLPVTPGMEGAGVVIAVGEGVSDRKAGDRVM-------------------------VLNR 139
PLPV G E AG+V +VGEGV+ K GD+V+ V N
Sbjct: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120
Query: 140 SGMWQEEVT-----------VPSVQTF------------LIPEAMTFEEAAALLVNYITA 176
G Q+ + + TF I A E+ + + T
Sbjct: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
Query: 177 YMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT-ASASKHEALKENGVT 235
Y + + PG + V GGVG++A+ C+ + + K KE G T
Sbjct: 181 YGSAVNVAKVTPGSTCAV-FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239
Query: 236 ---HPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLL--KPMGKVVTYGM--- 287
+P DY + +K+++ GVD + +G DT L + G V G+
Sbjct: 240 ECINPQDY-KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD 298
Query: 288 -ANLLTGPKRNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLL 346
NL P L+ RTW G LG + E V +VA +
Sbjct: 299 SQNLSMNPM--LLLTGRTW------------------KGAILGGFKSK-ECVPKLVADFM 337
Query: 347 ALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLL 385
A + + I V PFEK+ + + K++ +L+
Sbjct: 338 A--KKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILM 374
>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
sapiens]
Length = 375
Score = 48.9 bits (115), Expect = 8e-06
Identities = 86/369 (23%), Positives = 133/369 (36%), Gaps = 85/369 (23%)
Query: 74 PGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDR 133
P ++ +++ A G+ D G + + PLPV G E AG+V +VGEGV+ K GD+
Sbjct: 32 PKAYEVRIKMVAVGICHTDDHVVSG--NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDK 89
Query: 134 VMVL-------------------------NRSGMWQ-----------------------E 145
V+ L N G Q +
Sbjct: 90 VIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQ 149
Query: 146 EVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAA 205
V I A E+ + + T Y + + PG + V GGVG++A
Sbjct: 150 YTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVGLSA 208
Query: 206 VQLCRTVENVTVFGT-ASASKHEALKENGVT---HPIDYHTTDYVDEIKKISPKGVDIVM 261
V C+ + + K KE G T +P DY + +K+++ GVD
Sbjct: 209 VMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY-KKPIQEVLKEMTDGGVDFSF 267
Query: 262 DPLGGSDTAKGYNLL--KPMGKVVTYGM----ANLLTGPKRNLMALARTWWNQFSVTALQ 315
+ +G DT L + G V G+ NL P L+ RTW
Sbjct: 268 EVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPM--LLLTGRTW---------- 315
Query: 316 LLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQ 375
AV G +G +LV+ +A+ +L I V PFEK+ + +
Sbjct: 316 ----KGAVYG-GFKSKEGIPKLVADFMAKKFSL------DALITHVLPFEKINEGFDLLH 364
Query: 376 EKKNVGKVL 384
K++ VL
Sbjct: 365 SGKSIRTVL 373
>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
sapiens]
Length = 375
Score = 48.1 bits (113), Expect = 1e-05
Identities = 86/371 (23%), Positives = 137/371 (36%), Gaps = 89/371 (23%)
Query: 74 PGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDR 133
P ++ +++ A G+ +D G + + PLPV G E AG+V +VGEGV+ K GD+
Sbjct: 32 PKAHEVRIKMVAAGICRSDEHVVSG--NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDK 89
Query: 134 VMVL-------------------------NRSGMWQEEVT-----------VPSVQTF-- 155
V+ L N G Q+ V TF
Sbjct: 90 VIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQ 149
Query: 156 ----------LIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAA 205
I A E+ + + T Y + PG + V GGVG++
Sbjct: 150 YTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAV-FGLGGVGLSV 208
Query: 206 VQLCRTVENVTVFGT-ASASKHEALKENGVT---HPIDYHTTDYVDEIKKISPKGVDIVM 261
V C+ + + K KE G T +P DY + +K+++ GVD
Sbjct: 209 VMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY-KKPIQEVLKEMTDGGVDFSF 267
Query: 262 DPLGGSDTAKGYNLL--KPMGKVVTYGM----ANLLTGPKRNLMALARTWWNQFSVTALQ 315
+ +G DT L + G V G+ NL P L+ RTW
Sbjct: 268 EVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM--LLLTGRTW---------- 315
Query: 316 LLQANRAVCGFHLGYLDGE--VELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQ 373
A+ G G+ E +LV+ +A+ +L I ++ PFEK+ +
Sbjct: 316 ----KGAIFG---GFKSKESVPKLVADFMAKKFSL------DALITNILPFEKINEGFDL 362
Query: 374 MQEKKNVGKVL 384
++ K++ VL
Sbjct: 363 LRSGKSIRTVL 373
>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
Length = 349
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/194 (28%), Positives = 87/194 (44%), Gaps = 17/194 (8%)
Query: 81 LRLRACGLNFAD--LMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVL- 137
L+++AC L+ + L+A + L P+ G E AG+V+ VG VS + D V+ +
Sbjct: 35 LQVKACALSQINTKLLAEMKMKKDLFPV----GREIAGIVLDVGSKVSFFQPDDEVVGIL 90
Query: 138 ---NRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLV 194
+ E V V PE +T+ EAA + + + AY L +L PG SVL+
Sbjct: 91 PLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYLSHLSPGKSVLI 150
Query: 195 HMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKEN---GVTHPIDYHTTD-YVDE-- 248
A G A+QL V TA + + + E + ID +V E
Sbjct: 151 MDGASAFGTIAIQLAHH-RGAKVISTACSLEDKQCLERFRPPIARVIDVSNGKVHVAESC 209
Query: 249 IKKISPKGVDIVMD 262
+++ GVDIV+D
Sbjct: 210 LEETGGLGVDIVLD 223
>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
sapiens]
Length = 374
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/272 (21%), Positives = 96/272 (35%), Gaps = 59/272 (21%)
Query: 47 LLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPL 106
+++C + + ++ APP ++ +++ A + D G D
Sbjct: 5 VIKCKAAVAWEAGKPLSIEEIEVAPPKAH--EVRIKIIATAVCHTDAYTLSGA-DPEGCF 61
Query: 107 PVTPGMEGAGVVIAVGEGVSDRKAGDRVM------------------------------- 135
PV G EGAG+V +VGEGV+ KAGD V+
Sbjct: 62 PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG 121
Query: 136 ---------------VLNRSG--MWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYM 178
+L+ G + E V + I ++ L T Y
Sbjct: 122 LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYG 181
Query: 179 VLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT-ASASKHEALKENGVTHP 237
+ L+PG SV GGVG+A + C+ + G + K KE G T
Sbjct: 182 AAVNTAKLEPG-SVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATEC 240
Query: 238 IDYHTTDYVDEIKKI----SPKGVDIVMDPLG 265
I + D+ I+++ + GVD + +G
Sbjct: 241 I--NPQDFSKPIQEVLIEMTDGGVDYSFECIG 270
>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
sapiens]
Length = 380
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 6/133 (4%)
Query: 143 WQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVG 202
+ + V + I + E L + T Y + + PG + V GGVG
Sbjct: 152 FSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAV-FGLGGVG 210
Query: 203 MAAVQLCRTVENVTVFGTASAS----KHEALKENGVTHPIDYHTTDYVDEIKKISPKGVD 258
++AV C+ + G S K +AL +P D H + I +++ GVD
Sbjct: 211 LSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKP-IQEVIIELTKGGVD 269
Query: 259 IVMDPLGGSDTAK 271
+D GGS+T K
Sbjct: 270 FALDCAGGSETMK 282
Score = 34.3 bits (77), Expect = 0.20
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 47 LLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPL 106
+++C + + ++ APP ++ +++ A L D ++ L
Sbjct: 7 VIKCKAAIAWEAGKPLCIEEVEVAPPKAH--EVRIQIIATSLCHTDATVIDSKFEGLA-F 63
Query: 107 PVTPGMEGAGVVIAVGEGVSDRKAGDRVMVL 137
PV G E AG+V ++G GV++ K GD+V+ L
Sbjct: 64 PVIVGHEAAGIVESIGPGVTNVKPGDKVIPL 94
>gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]
Length = 375
Score = 38.9 bits (89), Expect = 0.008
Identities = 41/214 (19%), Positives = 73/214 (34%), Gaps = 55/214 (25%)
Query: 107 PVTPGMEGAGVVIAVGEGVSDRKAGDRVMVL----------------------------- 137
P G EGAG+V ++GEGVS K GD+V+ L
Sbjct: 64 PTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQL 123
Query: 138 ------------------NRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMV 179
+ + E + + I E+ + + T +
Sbjct: 124 MSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGA 183
Query: 180 LFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT-ASASKHEALKENGVTHPI 238
+ + PG + V GGVG++ V C+ + G + K + +E G T +
Sbjct: 184 AINTAKVTPGSTCAV-FGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECL 242
Query: 239 DYHTTDYVDEIKKI----SPKGVDIVMDPLGGSD 268
+ D I+++ + G+D + +G D
Sbjct: 243 --NPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLD 274
>gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]
Length = 368
Score = 38.9 bits (89), Expect = 0.008
Identities = 41/214 (19%), Positives = 73/214 (34%), Gaps = 55/214 (25%)
Query: 107 PVTPGMEGAGVVIAVGEGVSDRKAGDRVMVL----------------------------- 137
P G EGAG+V ++GEGVS K GD+V+ L
Sbjct: 64 PTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQL 123
Query: 138 ------------------NRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMV 179
+ + E + + I E+ + + T +
Sbjct: 124 MSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGA 183
Query: 180 LFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT-ASASKHEALKENGVTHPI 238
+ + PG + V GGVG++ V C+ + G + K + +E G T +
Sbjct: 184 AINTAKVTPGSTCAV-FGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECL 242
Query: 239 DYHTTDYVDEIKKI----SPKGVDIVMDPLGGSD 268
+ D I+++ + G+D + +G D
Sbjct: 243 --NPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLD 274
>gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit
[Homo sapiens]
Length = 386
Score = 34.7 bits (78), Expect = 0.15
Identities = 59/295 (20%), Positives = 100/295 (33%), Gaps = 75/295 (25%)
Query: 74 PGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDR 133
P ++ +++ A G+ D +G + PV G E G+V ++GEGV+ K GD+
Sbjct: 44 PKTKEVRIKILATGICRTDDHVIKGTM--VSKFPVIVGHEATGIVESIGEGVTTVKPGDK 101
Query: 134 VMVL-----------------------------------------------NRSGMWQEE 146
V+ L + + E
Sbjct: 102 VIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEY 161
Query: 147 VTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAV 206
V I +A E+ + + T Y G ++PG S V GGVG++ +
Sbjct: 162 TVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPG-STCVVFGLGGVGLSVI 220
Query: 207 QLCRTVENVTVFG-TASASKHEALKENGVTHPID-YHTTDYVDEI-KKISPKGVDIVMDP 263
C++ + G + K E G T I +T + E+ +++ V +
Sbjct: 221 MGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEV 280
Query: 264 LGGSDTA--------KGYNL-----LKPMGKVVTYGMANLLTGPKRNLMALARTW 305
+G +T Y + P K++TY L TG RTW
Sbjct: 281 IGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTG---------RTW 326
>gi|239741585 PREDICTED: hypothetical protein XP_002342243 [Homo
sapiens]
Length = 439
Score = 34.3 bits (77), Expect = 0.20
Identities = 39/138 (28%), Positives = 53/138 (38%), Gaps = 31/138 (22%)
Query: 18 SPPPKTEAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPG 77
+P P++ A Q + AA SP RC L+ +K P PPAP P
Sbjct: 281 TPVPQSVALPSLQSARPAAAGAAPRLSPQAARCTALS----TEKPDRPGPPRRPPAPTP- 335
Query: 78 QLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMV- 136
+ A L A L A + L +RLP V P E A R++ + MV
Sbjct: 336 -----VSAPTLRSAPLDAHR-LRERLPESSVGPRAEPA------------RRSRNAAMVS 377
Query: 137 -------LNRSGMWQEEV 147
R G+W+E V
Sbjct: 378 PRHQPGKARREGLWEEAV 395
>gi|226246682 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 33.9 bits (76), Expect = 0.26
Identities = 41/180 (22%), Positives = 81/180 (45%), Gaps = 14/180 (7%)
Query: 101 DRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEEV-----TVPSVQTF 155
D + P ++ ++G G+ I ++ GD V + WQ +V ++ V
Sbjct: 63 DYITPWQLSQVVDGGGIGIIEESKHTNLTKGD--FVTSFYWPWQTKVILDGNSLEKVDPQ 120
Query: 156 LIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHS--VLVHMAAGGVGMAAVQLCRTVE 213
L+ +++ A+ + +T+ + + + G++ G + ++V AAG G A Q+ +
Sbjct: 121 LVDGHLSYF-LGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLG 179
Query: 214 NVTVFGTASASKHEAL--KENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGG--SDT 269
V G + L E G I+Y + +++++ P GVD+ D +GG SDT
Sbjct: 180 CSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDT 239
>gi|226246680 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 33.9 bits (76), Expect = 0.26
Identities = 41/180 (22%), Positives = 81/180 (45%), Gaps = 14/180 (7%)
Query: 101 DRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEEV-----TVPSVQTF 155
D + P ++ ++G G+ I ++ GD V + WQ +V ++ V
Sbjct: 63 DYITPWQLSQVVDGGGIGIIEESKHTNLTKGD--FVTSFYWPWQTKVILDGNSLEKVDPQ 120
Query: 156 LIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHS--VLVHMAAGGVGMAAVQLCRTVE 213
L+ +++ A+ + +T+ + + + G++ G + ++V AAG G A Q+ +
Sbjct: 121 LVDGHLSYF-LGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLG 179
Query: 214 NVTVFGTASASKHEAL--KENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGG--SDT 269
V G + L E G I+Y + +++++ P GVD+ D +GG SDT
Sbjct: 180 CSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDT 239
>gi|22748929 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 33.9 bits (76), Expect = 0.26
Identities = 41/180 (22%), Positives = 81/180 (45%), Gaps = 14/180 (7%)
Query: 101 DRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEEV-----TVPSVQTF 155
D + P ++ ++G G+ I ++ GD V + WQ +V ++ V
Sbjct: 63 DYITPWQLSQVVDGGGIGIIEESKHTNLTKGD--FVTSFYWPWQTKVILDGNSLEKVDPQ 120
Query: 156 LIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHS--VLVHMAAGGVGMAAVQLCRTVE 213
L+ +++ A+ + +T+ + + + G++ G + ++V AAG G A Q+ +
Sbjct: 121 LVDGHLSYF-LGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLG 179
Query: 214 NVTVFGTASASKHEAL--KENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGG--SDT 269
V G + L E G I+Y + +++++ P GVD+ D +GG SDT
Sbjct: 180 CSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDT 239
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,036,371
Number of Sequences: 37866
Number of extensions: 739120
Number of successful extensions: 4351
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 87
Number of HSP's that attempted gapping in prelim test: 4168
Number of HSP's gapped (non-prelim): 233
length of query: 393
length of database: 18,247,518
effective HSP length: 104
effective length of query: 289
effective length of database: 14,309,454
effective search space: 4135432206
effective search space used: 4135432206
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.