Guide to the Human Genome
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Search of human proteins with 18379332

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18379332 WW domain-containing adapter with a coiled-coil
region isoform 3 [Homo sapiens]
         (544 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18379332 WW domain-containing adapter with a coiled-coil regi...  1088   0.0  
gi|18379328 WW domain-containing adapter with a coiled-coil regi...   988   0.0  
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             55   2e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    54   3e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   1e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        50   5e-06
gi|83367077 mucin 16 [Homo sapiens]                                    49   9e-06
gi|91982772 mucin 17 [Homo sapiens]                                    49   9e-06
gi|116284392 mucin 2 precursor [Homo sapiens]                          48   3e-05
gi|151301228 formin binding protein 3 [Homo sapiens]                   48   3e-05
gi|167736355 mucin 4 isoform a [Homo sapiens]                          47   3e-05
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       47   3e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    47   4e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    47   4e-05
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    46   8e-05
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo...    46   8e-05
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        46   1e-04
gi|219802034 nuclear factor related to kappaB binding protein is...    46   1e-04
gi|23346420 nuclear factor related to kappaB binding protein iso...    46   1e-04
gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 ...    45   1e-04
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    45   2e-04
gi|119943102 CREB binding protein isoform b [Homo sapiens]             45   2e-04
gi|119943104 CREB binding protein isoform a [Homo sapiens]             45   2e-04
gi|41281612 zinc finger protein 828 [Homo sapiens]                     45   2e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         45   2e-04
gi|114431248 hypothetical protein LOC205717 [Homo sapiens]             45   2e-04
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    45   2e-04
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    45   2e-04
gi|148612879 polyhomeotic like 3 [Homo sapiens]                        45   2e-04
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                44   3e-04

>gi|18379332 WW domain-containing adapter with a coiled-coil region
           isoform 3 [Homo sapiens]
          Length = 544

 Score = 1088 bits (2814), Expect = 0.0
 Identities = 544/544 (100%), Positives = 544/544 (100%)

Query: 1   MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR 60
           MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR
Sbjct: 1   MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR 60

Query: 61  RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN 120
           RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN
Sbjct: 61  RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN 120

Query: 121 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS 180
           PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS
Sbjct: 121 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS 180

Query: 181 FPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAV 240
           FPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAV
Sbjct: 181 FPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAV 240

Query: 241 PVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSII 300
           PVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSII
Sbjct: 241 PVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSII 300

Query: 301 HKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTV 360
           HKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTV
Sbjct: 301 HKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTV 360

Query: 361 PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRS 420
           PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRS
Sbjct: 361 PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRS 420

Query: 421 PSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQA 480
           PSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQA
Sbjct: 421 PSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQA 480

Query: 481 SRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQN 540
           SRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQN
Sbjct: 481 SRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQN 540

Query: 541 SFMV 544
           SFMV
Sbjct: 541 SFMV 544


>gi|18379328 WW domain-containing adapter with a coiled-coil region
           isoform 1 [Homo sapiens]
          Length = 647

 Score =  988 bits (2555), Expect = 0.0
 Identities = 524/647 (80%), Positives = 527/647 (81%), Gaps = 103/647 (15%)

Query: 1   MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR 60
           MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR
Sbjct: 1   MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR 60

Query: 61  RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN 120
           RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN
Sbjct: 61  RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN 120

Query: 121 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS 180
           PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS
Sbjct: 121 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS 180

Query: 181 FPKDRDYRREVMQATATSGFASGKST--SGD----------------------------- 209
           FPKDRDYRREVMQATATSGFASG     S D                             
Sbjct: 181 FPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETH 240

Query: 210 ----------KPVSHSCTTPST-----------------SSASGLNPTSAPPTSASAVP- 241
                     KPV H   TPST                   A+G +  S  PT  S+VP 
Sbjct: 241 SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300

Query: 242 --------------------------------------------VSPVPQSPIPPLLQDP 257
                                                       VSPVPQSPIPPLLQDP
Sbjct: 301 QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDP 360

Query: 258 NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI 317
           NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI
Sbjct: 361 NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI 420

Query: 318 SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV 377
           SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV
Sbjct: 421 SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV 480

Query: 378 STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA 437
           STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA
Sbjct: 481 STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA 540

Query: 438 TVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSE 497
           TVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSE
Sbjct: 541 TVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSE 600

Query: 498 ICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV 544
           ICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV
Sbjct: 601 ICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV 647


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 74/278 (26%), Positives = 116/278 (41%), Gaps = 38/278 (13%)

Query: 152  TEVSQWEKPKEWLEREQRQKEANKMAV----NSFPKDRDYRREV------MQATATSGFA 201
            TEV   ++ K   + E+R+KE   + V    N+  K R    ++       QAT      
Sbjct: 1682 TEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQ 1741

Query: 202  SGKST----SGDKPVSHSCTTPSTSSA---SGLNP----TSAPPTSASAVPV-----SPV 245
            S  S     S   P S S + P+++SA   + L P    TSAP  +++  PV     +PV
Sbjct: 1742 SSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPV 1801

Query: 246  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKI--NEVLTAAVTQASLQSIIHKF 303
            P SP+ P+    ++   + PA  +   + +S+   S      +L +  T AS+  +    
Sbjct: 1802 PASPLAPVSASASVSASV-PASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASAS 1860

Query: 304  LTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVS---PRISTPQTNTV 360
            +    SA   TS  + A   S+ A P   +P   T  AS+P + V       S P     
Sbjct: 1861 IPILASALASTSAPTPAPAASSPAAPVITAP---TIPASAPTASVPLAPASASAPAPAPT 1917

Query: 361  PIKPLISTPPVSSQPKVSTPVVKQGPV---SQSATQQP 395
            P+      PP  +Q +  T    Q P+   SQS+ Q P
Sbjct: 1918 PVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPP 1955


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 89/422 (21%), Positives = 167/422 (39%), Gaps = 20/422 (4%)

Query: 31  SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
           SS S  S  D       D+ D S  +     SDS ++  S  +  SK+ +  +    E D
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS----ESD 632

Query: 91  GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNC 150
              S S  ++S ++S+  S NS SS+ SN+ S +SD+   S    S   S S      + 
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNS-SNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691

Query: 151 RTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGKSTSGDK 210
            ++ S   +  +  +        +  + NS   D D        ++ S  +S  S S D 
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD--------SSNSSDSSDSSNSSDS 743

Query: 211 PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 270
             S S  + ++S +S  + +S    S+ +   S    S       D +       +  ++
Sbjct: 744 --SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801

Query: 271 LQLNNS-NVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQP 329
              N+S + D S  ++  ++  + +S  S       +  S+ +  S     +  S ++  
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861

Query: 330 SNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQ 389
           SN S  S +SD+S+         S   +N+       ++    S    ++        S 
Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921

Query: 390 SATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARST 449
            +++   ++D        S  S    SS  S S   + +SNSS++SN++    ++S+ S+
Sbjct: 922 DSSESSNSSDNSNS----SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977

Query: 450 CS 451
            S
Sbjct: 978 DS 979



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 82/408 (20%), Positives = 155/408 (37%), Gaps = 14/408 (3%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  SS         D+ D S  +     SDS ++  SDS+  S + N ++      +
Sbjct: 671  SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNC 150
               S     +S +  +  SSNS  S+ S++ S +SD+  DS+D      SS+        
Sbjct: 731  SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS-DSSDSSDSSDSSNS------- 782

Query: 151  RTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGKSTSGDK 210
             ++ +      +  +       +N    +      D        ++ S  +S  S S D 
Sbjct: 783  -SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841

Query: 211  PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 270
              S   +  S S +S  + +S    S+ +   S    S       D N       +  ++
Sbjct: 842  SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS---SDSNESSNSSDSSDSS 898

Query: 271  LQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPS 330
               ++ + D S  ++   ++ +  S +S  +    +  S  + +S  S ++  S  +  S
Sbjct: 899  NSSDSDSSDSSNSSDSSDSSNSSDSSES-SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957

Query: 331  NQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQS 390
            N S  S +SD+S   S  S   S    ++       S+    S     +        S +
Sbjct: 958  NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017

Query: 391  ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNAT 438
            ++    ++D     +  S  S    SS  S S   + +SNSS++S+++
Sbjct: 1018 SSDSSNSSDSSNSSDS-SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 96/453 (21%), Positives = 171/453 (37%), Gaps = 31/453 (6%)

Query: 12   SDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSD 71
            S    D    S    +   SSKS   S D   +   D+ D +        SDS +N  SD
Sbjct: 607  SSDSSDSSDSSDSSDSKSDSSKSESDSSD--SDSKSDSSDSN-------SSDSSDN--SD 655

Query: 72   STGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDS 131
            S+  S + N         D   S    ++S +  + +SS+S  S+ S+N S++SD+  DS
Sbjct: 656  SSDSSNSSN-------SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS-DS 707

Query: 132  ADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREV 191
            +D  S   S S      +  +  S                +++  + +S   D     + 
Sbjct: 708  SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDS 767

Query: 192  MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 251
              ++ +S  +S  S S D   S + +  S SS S  +  S+  + +S    S    S   
Sbjct: 768  SDSSDSSD-SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS 826

Query: 252  PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAF 311
                D +       +  ++   + S+ D S  ++   ++ +  S  S       +  S+ 
Sbjct: 827  SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS--SNSSDSSDSSD 884

Query: 312  NITSLISQAAQLSTQAQPSNQSPMSLTSDAS-SPRSYVSPRISTPQTNTVPIKPLISTPP 370
            +  S  S  +  S+ +  S+ S  S +SD+S S  S  S   S    N        S   
Sbjct: 885  SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN--------SNSS 936

Query: 371  VSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSN 430
             SS    S+        S S+     +          S  S   +SS  S S   + +S+
Sbjct: 937  DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996

Query: 431  SSNASNATVVPQNSSARSTCSLTPALAAHFSEN 463
            SS++SN++    +S +  + + + +  +  S N
Sbjct: 997  SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 93/454 (20%), Positives = 166/454 (36%), Gaps = 36/454 (7%)

Query: 12  SDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSD 71
           S G  D   DS        +S ++ S  +       D  D S   K   +SDS ++  SD
Sbjct: 507 SKGAEDDDSDS--------TSDTNNSDSNGNGNNGNDDNDKSDSGK--GKSDSSDSDSSD 556

Query: 72  STGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDS 131
           S+  S + +       + D   S S  ++  + S    S+   S+ S+N S +SD+  DS
Sbjct: 557 SSNSSDSSD-----SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS-DS 610

Query: 132 ADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREV 191
           +D      SS  K       ++ S  +   +  +        N  + +S           
Sbjct: 611 SDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD 670

Query: 192 MQATATSGFASGKSTSGDKPVS--HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
              ++ S  +S  S S D   S   S ++ S+ S+   +  S+  + +S    S    S 
Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730

Query: 250 IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
                   N       +  +    ++ + D S  ++   ++ +  S  S       +  S
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS-------SNSS 783

Query: 310 AFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP 369
             N +S  S ++  S  +  SN S  S +SD+S   S  S   S             S  
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS-----------SDS 832

Query: 370 PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTS 429
             SS    S+        S S +     +         S  S    SS  S S   +++S
Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892

Query: 430 NSSNASNATVVPQNSSARSTCSLTPALAAHFSEN 463
           +SS++SN++    + S+ S+ S   + ++  SE+
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 80/418 (19%), Positives = 153/418 (36%), Gaps = 29/418 (6%)

Query: 21   DSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKN 80
            DS    +   S  S+ +S D       D+ D S  +     SDS  +  S  +  S   +
Sbjct: 706  DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765

Query: 81   VHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHIS 140
              +      D   S +  +++ + ++  SS+S +S+ S+N S +SD+  DS+D  S + S
Sbjct: 766  DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS-DSSDSDSSNSS 824

Query: 141  SSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGF 200
             S      +  +  S      +  +           + NS              ++ S  
Sbjct: 825  DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS------------SDSSDSSD 872

Query: 201  ASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +S  S S D   S+  +  S SS S  +  S    S+++   S    S            
Sbjct: 873  SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS----------- 921

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQA 320
                 + +++   +NSN   S  N   ++  + +S  S       +  S+ +  S  S +
Sbjct: 922  ----DSSESSNSSDNSNSSDSS-NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976

Query: 321  AQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTP 380
            +  S  +  S+ S  S +SD+S   +      S+  +++       ++   S+    S  
Sbjct: 977  SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036

Query: 381  VVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNAT 438
                     S +     +         S  S    SS  S S   + +S+SS++SN++
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 1/113 (0%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  SS         D+ D S  +     SDS ++  S  +  S   +  +      D
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDS-ADDWSEHISSS 142
               S    ++S +  +  SSNS  S+ S++ S +SD+   S + D SE   SS
Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 1/111 (0%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  SS         D+ D S  +     SDS ++  S ++  S   +  +      D
Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD 1158

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISS 141
               S    ++S +  +  SSNS  S+ S++ S +SD+  DS+D      SS
Sbjct: 1159 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSDSS 1208



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 41/211 (19%), Positives = 80/211 (37%), Gaps = 2/211 (0%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  SS         D+ D S  +     SDS ++  S  +  S   +  +      +
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDA--PYDSADDWSEHISSSGKKYYY 148
               S    ++S +  +  SS+S  S+ S+N S +SD+    DS+D  +   SS   +   
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152

Query: 149  NCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGKSTSG 208
            +  +  S                +++  + +S   D     +   ++ +S  +    +S 
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212

Query: 209  DKPVSHSCTTPSTSSASGLNPTSAPPTSASA 239
                S S  +  +S +S  N +S    S+ +
Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 43/208 (20%), Positives = 83/208 (39%), Gaps = 2/208 (0%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  SS         D+ D S  +     S+S ++  S ++  S   +  +      D
Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNC 150
               S    ++S++  +  SS+S  S+ S+N S +SD+   S    S   S S      + 
Sbjct: 1111 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170

Query: 151  RTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGKSTSGDK 210
             ++ S      +  +      +++  + +S   D     +   ++ +S  +S  S S D 
Sbjct: 1171 SSDSSDSSNSSDSSDSSD-SSDSSDSSDSSDSSDSSDSSDSSDSSDSSD-SSDSSDSSDS 1228

Query: 211  PVSHSCTTPSTSSASGLNPTSAPPTSAS 238
              S+  +  S SS S  +  S+  + +S
Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSSDSSDSS 1256



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 49/227 (21%), Positives = 84/227 (37%), Gaps = 11/227 (4%)

Query: 12   SDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSD 71
            S    D    S    +   S+ S   S D  +    D+ D S  +     S+S +N  S 
Sbjct: 879  SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS--DSSDSSNSSDSSESSNSSDNSNSS 936

Query: 72   STGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDS 131
             + +S   +  +      D   S     +S N S    SNS  S+ S+N S +SD+  DS
Sbjct: 937  DSSNSSDSSDSSDSSNSSDSSNS----SDSSNSSDSSDSNSSDSSDSSNSSDSSDSS-DS 991

Query: 132  ADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREV 191
            +D      SS+      +  +  S                +++  + +S   D     + 
Sbjct: 992  SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD- 1050

Query: 192  MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS 238
               ++ S  +S  S S D   S   +  S SS S  +  S+  +++S
Sbjct: 1051 ---SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 80/430 (18%), Positives = 163/430 (37%), Gaps = 33/430 (7%)

Query: 22  SQPYQALKYSSKSHPSSGDHRH-----EKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHS 76
           S+P   + +S+    S+ D        +K     DP+  ++     D+  N  SD+   S
Sbjct: 430 SEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDA--NSESDNNSSS 487

Query: 77  KAK-NVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSS------NPSNNPSKTSDAPY 129
           +   + ++   ++   G+     E+  + S   ++NS S+      N  N+ S +     
Sbjct: 488 RGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKS 547

Query: 130 DSAD-DWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYR 188
           DS+D D S+  +SS      +  +  S      +  + +      +  + +S   D    
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607

Query: 189 REVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQS 248
            +   ++ +S  +  KS S  K  S S  + S S +S  N + +   S S+   +    S
Sbjct: 608 SDSSDSSDSSDSSDSKSDS-SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666

Query: 249 PIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGP 308
                    +          ++   ++++ D S  ++   ++ +  S  S       +  
Sbjct: 667 DSSDSSDSSD---------SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717

Query: 309 SAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLIST 368
           S+ N  S  S ++  S  +  SN S  S +SD+S+         S+  +++       S 
Sbjct: 718 SS-NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDS-------SD 769

Query: 369 PPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHT 428
              SS    S+        S S+     +      +   S  S   S S  S S   +++
Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829

Query: 429 SNSSNASNAT 438
           S+SS++SN++
Sbjct: 830 SDSSDSSNSS 839



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 23/104 (22%), Positives = 44/104 (42%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  SS         D+ D S  +     SDS E+  S  +  S   +  +      D
Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD 1257

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADD 134
               S S   +  +  +   + +++ + S++ S+ SD+ + ++DD
Sbjct: 1258 SSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 25/111 (22%), Positives = 41/111 (36%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  SS         D+ D S  +     SDS ++  S  +  S   +  +      +
Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISS 141
               S    ++S + S  +  +   S   N  +  SD+  DS    S H +S
Sbjct: 1249 SSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 67/255 (26%), Positives = 104/255 (40%), Gaps = 35/255 (13%)

Query: 205 STSGDKPVSHSCTTPSTSSAS-GLNPTSAPPTSASAVPVSP--VPQSPIPPLLQDPNLLR 261
           S     PVS S T PS +  S    P   PP+  ++ P+SP   P    PP L  P L  
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL-- 735

Query: 262 QLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAA 321
           Q+ P+  A+  ++ S     ++  +L A   Q              P +   +  +S  A
Sbjct: 736 QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV-------------PPSPPASLPMSPLA 782

Query: 322 QLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPV 381
           +   QA P+  +P  L +  S P S+      +P   ++P+ PL +TPP  + P ++ P+
Sbjct: 783 KPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSA-SLPMSPL-ATPPPQAPPVLAAPL 839

Query: 382 VKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQR-------SPSPGPNHTSNSSNA 434
           ++  P        P +   Q    P +P      S  R        P P P+  S SS  
Sbjct: 840 LQVPP------SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR-SPSSTL 892

Query: 435 SNATVVPQNSSARST 449
           S   +   +SSA ST
Sbjct: 893 SGPDLAGHSSSATST 907



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 62/252 (24%), Positives = 88/252 (34%), Gaps = 42/252 (16%)

Query: 213 SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ 272
           S   T PS +  S   P    P S   +P   VP S   P LQ P      L +LQAT  
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS-PLALSSLQATTS 417

Query: 273 LNNSNVDISKINEVLTAAVTQASLQSI------------------------IHKFLTAGP 308
           L +  +  +     ++   TQASL S                         +   L+   
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477

Query: 309 SAFNITSLISQAAQLSTQAQPSNQSPMS--LTSDASSPRSYVSPRISTPQTN--TVPIK- 363
           S  +    I     LS+ A  S Q+P+S  +     +  S   P + TP  +  T P++ 
Sbjct: 478 SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN 537

Query: 364 -PLISTPPVSSQ-----------PKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS 411
            P ++ PP+ +            P    P   Q P S   T  P T        P +P +
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597

Query: 412 LQRSSSQRSPSP 423
           L     Q  PSP
Sbjct: 598 LASPPLQGLPSP 609



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 61/248 (24%), Positives = 89/248 (35%), Gaps = 19/248 (7%)

Query: 219 PSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNV 278
           PS    +  +P ++PP S SA P S  P S   P LQ P       P+  A+  ++ S  
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-------PSPPASPPMSPSAT 721

Query: 279 DISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLT 338
              +    L A   Q          ++   +       +  A  L     P    PM   
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM--- 778

Query: 339 SDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQ-QPVT 397
           S  + P     P ++TP    +P  P          P  S P+    P++    Q  PV 
Sbjct: 779 SPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---SPLATPPPQAPPVL 835

Query: 398 ADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATV----VPQNSSARSTCSLT 453
           A       P  P S    + +R P+PGP+ + +    + A       P + S  ST S  
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS-G 894

Query: 454 PALAAHFS 461
           P LA H S
Sbjct: 895 PDLAGHSS 902



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 61/273 (22%), Positives = 96/273 (35%), Gaps = 36/273 (13%)

Query: 203 GKSTSGDKPVSHSCTTPST------SSASGLNPTSAPPTSASAVPVSP----------VP 246
           G   S      HS T PS       S+  GL   ++   S+SA P+S            P
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263

Query: 247 QSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTA 306
           ++P  P    P  L+ L P      Q+     D +     L+++       S        
Sbjct: 264 RAPAHPSQPKPKGLQALRPP-----QVTPPRKDAAPALGPLSSSPLATPSPS-------- 310

Query: 307 GPSAFNITSLISQAAQLSTQAQPSNQ--SPMSLTSDASSPRSYVSPRISTPQTNTVPIKP 364
           G  A  +    + A  L     PS    +P+ L   + S    +    S P T      P
Sbjct: 311 GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370

Query: 365 LISTPPVSSQPKVSTPVVKQGP-----VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQR 419
            ++TPP+ + P + T    Q P      S  A   P+     Q    +   +LQ + S  
Sbjct: 371 SMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL 430

Query: 420 SPSPGPNHTSNSSNASNATVVPQNSSARSTCSL 452
           + SP     S +S +  A+  P +   ++  SL
Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 65/272 (23%), Positives = 113/272 (41%), Gaps = 31/272 (11%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLNPTSAP---------PTSASAVPVSPVPQSPIPP 252
            SG+++      + S T PS  S S +    AP         P+ +   P    P+SP+P 
Sbjct: 2394 SGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPS 2453

Query: 253  LLQDPN--LLRQLLPALQ-------ATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF 303
               D +  L+ Q  P          A     +S  D + +  V    V  + +       
Sbjct: 2454 AFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST 2513

Query: 304  LTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIK 363
                PSA  + +L     + S+ +  S+ S  S +S +SS  S      S  + +++P++
Sbjct: 2514 GAQQPSA--LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ 2571

Query: 364  PLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSP 423
            P ++   V S     TP  K+  V +    +P  A +++     S  S   SSS  S S 
Sbjct: 2572 PEVALKRVPSP----TPAPKEA-VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS- 2625

Query: 424  GPNHTSNSSNASNATVVPQNSSARSTCSLTPA 455
                 S+SS++S+++    +SS+ S+ S +PA
Sbjct: 2626 -----SSSSSSSSSSSSSSSSSSSSSSSPSPA 2652



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 63/287 (21%), Positives = 106/287 (36%), Gaps = 43/287 (14%)

Query: 207  SGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPA 266
            +G + +S      +TSSA   N   + P  A  VP S V + P     Q P+ L  L PA
Sbjct: 2470 AGSQSLSSGAVATTTSSAGDHNGMLSVP--APGVPHSDVGEPPASTGAQQPSALAALQPA 2527

Query: 267  LQATLQLNNSNVDISKINEVLTAAVTQASLQS---------------------------- 298
             +     ++S+   S  +   +++ + +S  S                            
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587

Query: 299  -IIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQT 357
              + +     P+        S ++  S+ +  S+ S  S +S +SS  S  S   S+  +
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647

Query: 358  NTVPIKPLISTPPVSSQPKVSTPVVKQG-----PV-----SQSATQQPVTADKQQGHEPV 407
            +  P KP     P  + PK   P  ++      P+     S+S +  PV  ++++     
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPV--ERRRPSPQP 2705

Query: 408  SPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            SPR  Q SSS+R    G    S S +       P     R   S +P
Sbjct: 2706 SPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 47/145 (32%), Positives = 67/145 (46%), Gaps = 25/145 (17%)

Query: 318 SQAAQLSTQAQPSNQSPMSLTSDASSP----------RSYVSPRISTPQTNTVPIKPLIS 367
           S+    STQ +PS  SP + T   SSP          +S   P  S  +++T P +P   
Sbjct: 311 SEPGTTSTQ-RPS--SPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGP-EPPAP 366

Query: 368 TPPV------SSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
           TP +      S QP  +TP+  Q PV+  +   P T D+     P SP  L +SSS  S 
Sbjct: 367 TPLLAERHGGSPQPLATTPL-SQEPVNPPSEASP-TRDRSP---PKSPEKLPQSSSSESS 421

Query: 422 SPGPNHTSNSSNASNATVVPQNSSA 446
            P P  T  S +AS++   P+ + A
Sbjct: 422 PPSPQPTKVSRHASSSPESPKPAPA 446



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 41/156 (26%), Positives = 69/156 (44%), Gaps = 13/156 (8%)

Query: 97   PQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQ 156
            P +   + S+  SS+S SS+ S++ S +S +   S+D      SS   +     +   S 
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG---SSLPVQPEVALKRVPSP 2582

Query: 157  WEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSC 216
               PKE + RE R  E         P     +R    ++++S  +S  S+S     S S 
Sbjct: 2583 TPAPKEAV-REGRPPE---------PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS 2632

Query: 217  TTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPP 252
            ++ S+SS+S  + +S+P  +       P P SP  P
Sbjct: 2633 SSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKP 2668



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 56/256 (21%), Positives = 103/256 (40%), Gaps = 24/256 (9%)

Query: 23  QPYQALKYSSKSH-PSSGDHRHEKMRDAG---DPSPPN--------KMLRRSDSPENKYS 70
           +PY  ++ SS S  P+    + +K +D G   + S P         K   RS+S   K  
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK 228

Query: 71  DSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDA-PY 129
             +   K+K     + R+R   T+ +P ++   H +  + ++ SS+ S + S+++ A  +
Sbjct: 229 HRSPTPKSKRKSKDKKRKRSRSTTPAP-KSRRAHRSTSADSASSSDTSRSRSRSAAAKTH 287

Query: 130 DSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRR 189
            +A        +SG++   +     + + +P     +     E      +S  +D+D  +
Sbjct: 288 TTALAGRSPSPASGRRGEGD-----APFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDK 342

Query: 190 EVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
           +   AT  S      ST  + P      TP  +   G +P     T  S  PV+P P   
Sbjct: 343 KEKSATRPSPSPERSSTGPEPP----APTPLLAERHGGSPQPLATTPLSQEPVNP-PSEA 397

Query: 250 IPPLLQDPNLLRQLLP 265
            P   + P    + LP
Sbjct: 398 SPTRDRSPPKSPEKLP 413



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 61/255 (23%), Positives = 100/255 (39%), Gaps = 23/255 (9%)

Query: 218  TPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSN 277
            TP+  +A  L  +  PPT+A+    S  PQ+P    L  P       P   A  +   + 
Sbjct: 2302 TPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAAL 2361

Query: 278  VDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITS--LISQAAQLSTQAQPSNQ--- 332
               S  +  +  A++ A+L S     L+A       TS  L+ +A   +  + PS     
Sbjct: 2362 APASLTSARMAPALSGANLTS-PRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMT 2420

Query: 333  -----SPMSLTSDASS----PRSYVSPRISTPQTNTVPIKPLIS-TPPVSSQPKVSTPVV 382
                 SP S    A S    P +   PR   P   +   + LI+ T PV+    +S+  V
Sbjct: 2421 SERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV 2480

Query: 383  KQGPVSQS------ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASN 436
                 S        +   P       G EP +    Q+ S+  +  P     S+SS++S+
Sbjct: 2481 ATTTSSAGDHNGMLSVPAPGVPHSDVG-EPPASTGAQQPSALAALQPAKERRSSSSSSSS 2539

Query: 437  ATVVPQNSSARSTCS 451
            ++    +SS+ S+ S
Sbjct: 2540 SSSSSSSSSSSSSSS 2554



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 103/505 (20%), Positives = 169/505 (33%), Gaps = 75/505 (14%)

Query: 5    ARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDS 64
            AR++ R       R     P +    S    P+       +       S      RRS  
Sbjct: 621  ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGR 680

Query: 65   PENKYSDSTGHSKAKNVHTHRVRERD---GGTSYSPQENSHNHSALHSSNSHSSNPSNNP 121
              ++     G S+++     R R R     G S+S        S   S   + S  S   
Sbjct: 681  SRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRR 740

Query: 122  SKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEK-------PKEWLEREQRQKEAN 174
            S+++ +P       S   S S        ++ +S           PK+  +   R+  + 
Sbjct: 741  SRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSG 800

Query: 175  KMAVNSFPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPP 234
                +S PK +         +++S     KS +  +  SHS ++P     SG  P     
Sbjct: 801  ----SSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ-SHSSSSPHPKVKSGTPPRQGSI 855

Query: 235  TSASAVPVSPVPQ-------SPIPPLL-----------QDPNLLRQLLPALQATLQLNNS 276
            TS  A   S  PQ       SP P L              P  ++   P  Q+    + S
Sbjct: 856  TSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP---SRS 912

Query: 277  NVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQS--- 333
            +    K+  +++      S  S         PS   +TS  +     S     + +S   
Sbjct: 913  SSPQPKVKAIISPRQRSHSGSS--------SPSPSRVTSRTTPRRSRSVSPCSNVESRLL 964

Query: 334  PMSLTSDASSPRSYVSPRISTPQTNTVPIKPL----ISTPPVSS---------QPKVSTP 380
            P    S +SSP + V P     Q+++  I P       TPP  S         Q K    
Sbjct: 965  PRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDS 1024

Query: 381  VVKQGPVSQS------ATQQP------VTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHT 428
            +V+  P S S      ++  P      V++ + +G    SP      S   SP    +H+
Sbjct: 1025 LVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP---DHRSDTSSPEVRQSHS 1081

Query: 429  SNSSNASNATVVPQNSSARSTCSLT 453
             + S  S +   P+   +RS+  +T
Sbjct: 1082 ESPSLQSKSQTSPKGGRSRSSSPVT 1106



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 75/378 (19%), Positives = 117/378 (30%), Gaps = 67/378 (17%)

Query: 86  VRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKK 145
           VRE     S +P++            S SS+P     K                SS  KK
Sbjct: 174 VRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKK----------------SSKKKK 217

Query: 146 YYYNCRTEVSQWEKPKEWLEREQRQKEANKM-AVNSFPKDRDYRREVMQATATSGFASGK 204
           +     ++  +   P    +R+ + K+  +  +    PK R   R     +A+S   S  
Sbjct: 218 HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS 277

Query: 205 STSGDKPVSHSCTTP--STSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQ 262
            +      +H+      S S ASG       P S      +  P SP             
Sbjct: 278 RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPET----------- 326

Query: 263 LLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQ 322
                 AT Q ++   D  K  +  +A     S +                        +
Sbjct: 327 ------ATKQPSSPYEDKDKDKKEKSATRPSPSPE------------------------R 356

Query: 323 LSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVV 382
            ST  +P   +P+       SP+    P  +TP +      P  ++P     P  S   +
Sbjct: 357 SSTGPEPPAPTPLLAERHGGSPQ----PLATTPLSQEPVNPPSEASPTRDRSPPKSPEKL 412

Query: 383 KQGPVSQSA--TQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNS-SNASNATV 439
            Q   S+S+  + QP    +     P SP+      S R  S  P   + S   A     
Sbjct: 413 PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKS 472

Query: 440 VPQNSSARSTCSLTPALA 457
                S R   S +PA A
Sbjct: 473 HSHTPSRRMGRSRSPATA 490



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 37/173 (21%), Positives = 63/173 (36%), Gaps = 15/173 (8%)

Query: 294  ASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSP--- 350
            A   ++  +   A  +A N+ S  + A   +     S     +   + +SPR+ V+P   
Sbjct: 2223 APAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAV 2282

Query: 351  RISTPQTNTVPIKPLIS--TP----PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGH 404
             ++ P+T T P   L    TP     +S     + P     P S    Q P +A+     
Sbjct: 2283 NLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANL---- 2338

Query: 405  EPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALA 457
              V PRS   ++               ++ ++A + P  S A  T    P  A
Sbjct: 2339 --VGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSA 2389



 Score = 29.3 bits (64), Expect = 9.6
 Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 6/114 (5%)

Query: 325  TQAQPSNQSPMSLTSDASSPR---SYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPV 381
            T  + S  SP   T   + PR   S  SP ++     +   +   S+P   S+   + P 
Sbjct: 1667 TARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR---TPPR 1723

Query: 382  VKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNAS 435
             ++ P   S      +   ++     SPR+   S   RSPSP P     S + S
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRS 1777


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 84/367 (22%), Positives = 143/367 (38%), Gaps = 32/367 (8%)

Query: 93   TSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNCRT 152
            TS  P  +S +H  L +    ++  + +PS TS A  +     S H S S         +
Sbjct: 6854 TSSPPNLSSTSHEILTTDEDTTAIEAMHPS-TSTAATNVETTSSGHGSQSSVL----ADS 6908

Query: 153  EVSQWEKPKEWLEREQRQKEANKMAVNSFPKD--RDYRREVMQATATSGFASGKSTSGDK 210
            E ++   P +          +  M+V+S      R+    +      +  +   S S D 
Sbjct: 6909 EKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDT 6968

Query: 211  PVSHS-CTTPSTSSASGLNPTSAPPTSASAVPVSPVP-QSPIPPLLQDPNLLRQLL-PAL 267
             +  S   T +T+  S    TS+  TS       P P QS + P +    + R    P +
Sbjct: 6969 SIVLSEVPTGTTAEVSRTEVTSSGRTSI------PGPSQSTVLPEISTRTMTRLFASPTM 7022

Query: 268  QATLQLN---NSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQA-AQL 323
              + ++     +    S   + LT   +    Q+  H  LT       +T+L+S+    +
Sbjct: 7023 TESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDM 7082

Query: 324  STQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVK 383
            S Q+ PS ++P SL S  S P +   P IS+    T+   PL  T  ++S P  +T ++ 
Sbjct: 7083 SWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLH 7142

Query: 384  QGP---------VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG---PNHTSNS 431
              P         +S ++ ++  T       E V P +   +S+   PS G   P+     
Sbjct: 7143 TSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALAD 7202

Query: 432  SNASNAT 438
            S  S AT
Sbjct: 7203 SETSKAT 7209



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 64/285 (22%), Positives = 113/285 (39%), Gaps = 25/285 (8%)

Query: 189  REVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASG-----LNPTSAPPTSASAVPVS 243
            R  +    ++ F SG  ++  +  SHS  T   S   G      +P+    +SAS    S
Sbjct: 9091 RGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLSS 9150

Query: 244  PV--PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAA---VTQASLQS 298
            PV    SP+   L D      L      T  L  +   +   +E  T++   ++  S + 
Sbjct: 9151 PVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAEI 9210

Query: 299  IIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTN 358
            +    +T       +T++++      T   PS+    S+T+ A+S      P   T  TN
Sbjct: 9211 LAITEVTTDTEKLEMTNVVTSG---YTHESPSSVLADSVTTKATSSMGITYP---TGDTN 9264

Query: 359  TVPIKPLIS-TPPVSSQPKVS-TPVVKQGPVSQ---SATQQPVTADKQQGHEPVSPRSLQ 413
             +   P  S T  + ++ K+S TP + +  +S+   SAT++                  +
Sbjct: 9265 VLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTE 9324

Query: 414  RSSSQRSPSPGPNHTSNSSNASNATV----VPQNSSARSTCSLTP 454
              SS R+  PGP  ++ SS+ S  T+     P      +  ++TP
Sbjct: 9325 AISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITP 9369



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 61/249 (24%), Positives = 93/249 (37%), Gaps = 21/249 (8%)

Query: 194  ATATSGFASGKSTS----GDKPVSHSCTTP--STSSASGL-------NPTSAPPTSASAV 240
            +T T GF   + T+    G   VS   T P   TSS S L       +P+    TS  ++
Sbjct: 5299 STVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSI 5358

Query: 241  PVSPVPQSPIPP--LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQS 298
            P SP+P + +P   L+   ++L    P    +   N S++   +       A T+A++  
Sbjct: 5359 PSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHH 5418

Query: 299  IIHKFLT-AGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQT 357
              +  +T  G S     S  S  A   T       S  S   D S   S  +P IS  QT
Sbjct: 5419 STNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTS--TPNIS--QT 5474

Query: 358  NTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 417
            N +  +P  S  P   +   S         + + +  P  A  Q     +S      S  
Sbjct: 5475 NQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISDL 5534

Query: 418  QRSPSPGPN 426
             R P+  P+
Sbjct: 5535 DR-PTIAPD 5542



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 82/360 (22%), Positives = 131/360 (36%), Gaps = 38/360 (10%)

Query: 110  SNSHSSNPSNNPSKTSDAPYDSADDW--SEHISSSGKKYYYNCRTEVSQWEKPKEWLERE 167
            S    ++ ++N S TS     + +D   +E +  S      N RT +S  E     L   
Sbjct: 8314 SREPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDS 8373

Query: 168  QRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGK-STSGDKPVSHSCTTPSTSSASG 226
            +  K  + M                  T T G  S   STS     S     P++S  SG
Sbjct: 8374 ETPKATSPMGT----------------TYTMGETSVSISTSDFFETSRIQIEPTSSLTSG 8417

Query: 227  LNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEV 286
            L  TS+    +SA   S V      P      + R  + + + T         IS   ++
Sbjct: 8418 LRETSSSERISSATEGSTVLSEV--PSGATTEVSRTEVISSRGTSMSGPDQFTISP--DI 8473

Query: 287  LTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRS 346
             T A+T+ S   I+ +   +  SA  I +    A    T    ++ +     + +++   
Sbjct: 8474 STEAITRLSTSPIMTE---SAESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPG 8530

Query: 347  YVSPRISTPQTNTVPIKPLISTPPV----------SSQPKVSTPVVKQGPVSQSATQQPV 396
            +    ++T  + T    P  S P V          SS    ST      P S S++  PV
Sbjct: 8531 FSHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPV 8590

Query: 397  TADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPAL 456
            TA    G  PV    + R+SS+   S  PN +S S+     + V ++       S TP +
Sbjct: 8591 TALLTLG--PVKTTDMLRTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVV 8648



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 109/468 (23%), Positives = 179/468 (38%), Gaps = 66/468 (14%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            S+K+ PSS       + +A   SP  + +R + SP    S S G   A +V T       
Sbjct: 760  STKTKPSSAVLSSMTLSNAAT-SP--ERVRNATSPLTHPSPS-GEETAGSVLT---LSTS 812

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNC 150
              T+ SP  N H    L S +S S +  + PS +      S+   S H+ +SG++     
Sbjct: 813  AETTDSP--NIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETS 870

Query: 151  RTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGKSTSGDK 210
               VSQ   P+  + R +    +  +    FP    +       T ++ F+S    S  +
Sbjct: 871  NPSVSQ---PETSVSRVRTTLASTSVPTPVFPTMDTW------PTRSAQFSSSHLVSELR 921

Query: 211  PVSHSCTTPSTSSA----SGLNPTSA-PPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLP 265
              S +  T ST SA    S L  T+    T+      S  PQS   P  +     +  LP
Sbjct: 922  ATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWP--ETSPRFKTGLP 979

Query: 266  ALQATLQLN----NSNVDISKINEVLTAAVTQASLQ----SIIHKFLTAGPSAFNITSL- 316
            +   T+  +    ++ V +SK     T+++   S++    +I+    T GP +  + S  
Sbjct: 980  SATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTN 1039

Query: 317  ------ISQAAQLSTQAQPSNQSPMSLTS-DASSPRSYVSPRISTPQTNTVPIKPLISTP 369
                       +L T   P   +  S TS D +  +  VS  +S  Q+         STP
Sbjct: 1040 IPIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGS---STP 1096

Query: 370  PVSSQ----------PKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS-----LQR 414
              +SQ             S  +      + SA    +TA      +P S RS     L  
Sbjct: 1097 GRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTWLGILSS 1156

Query: 415  SSSQRSPSPGPNHTSNSSNASNATVVPQNSSAR-------STCSLTPA 455
            S S  +P    + T ++   + + ++    ++R       ST SLTP+
Sbjct: 1157 SPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPS 1204



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 41/243 (16%)

Query: 219  PSTSSASGLNPTSAPPTSASA----VPVSPVPQSPIPPLL-QDPNLLRQLLPALQATLQL 273
            P  S++ G      P TS+ A    +     P S +  ++ +DP +L   +P        
Sbjct: 6742 PLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSF 6801

Query: 274  NNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNIT-SLISQAAQLSTQAQPSNQ 332
            ++S +     +  +T+    ++L   IH   T  P    +T SL+     L T  +P+  
Sbjct: 6802 SSSLMP----SPAMTSPPVSSTLPKTIHT--TPSPMTSLLTPSLVMTTDTLGTSPEPTTS 6855

Query: 333  SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSA- 391
            SP +L+S         S  I T   +T  I+ +    P +S    +      G  SQS+ 
Sbjct: 6856 SPPNLSS--------TSHEILTTDEDTTAIEAM---HPSTSTAATNVETTSSGHGSQSSV 6904

Query: 392  --------TQQPVTADKQQGHEPVSPRSLQRSS--------SQRSPSPGPNHTSNSSNAS 435
                       P+      GH  VS  S+  SS        S  S +PG   TS S NAS
Sbjct: 6905 LADSEKTKATAPMDTTSTMGHTTVS-TSMSVSSETTKIKRESTYSLTPGLRETSISQNAS 6963

Query: 436  NAT 438
             +T
Sbjct: 6964 FST 6966



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 66/297 (22%), Positives = 109/297 (36%), Gaps = 46/297 (15%)

Query: 191  VMQATATSGFASGKSTSGD-KPVSHSC-----TTPSTSSASGLNPTSAPPTSASAVPVSP 244
            + QAT T   +S  S  G   PV+        TT  + S  G++  S P    ++ P SP
Sbjct: 5871 ISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSP 5930

Query: 245  VPQSPIPPLLQDPNLLRQL--------LPALQATLQLNNSNVD-ISKINEVLTAAVTQAS 295
            VP   +P +    +L   +        LP            +D +   +E++T+++  AS
Sbjct: 5931 VP---LPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSAS 5987

Query: 296  --------------LQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDA 341
                           ++I     TA  +     S+    + +S  +QPS  +P  +T   
Sbjct: 5988 SFSGEILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSM 6047

Query: 342  SSPRSYVSPRISTPQTNTV------PIKPLI---STPPVSSQPKVSTPVVKQGPVSQSAT 392
                   +    +P+T  V      P+ P +   ST  V +    S  V     VS  A 
Sbjct: 6048 MEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSS--VSLDAA 6105

Query: 393  QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARST 449
             +   A+         P S Q   S +SP   P  +S+ SN+   T+    + A  T
Sbjct: 6106 TEVSRAEVTYYDPTFMPASAQ---STKSPDISPEASSSHSNSPPLTISTHKTIATQT 6159



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 60/272 (22%), Positives = 102/272 (37%), Gaps = 48/272 (17%)

Query: 194  ATATSGFASGKSTS------GDKPVSHSCTTPSTSSASG---LNPTSAPPTSASAVPVSP 244
            +T + GF   + T+      GD  VS   T P   ++SG   ++P+   P+  S+     
Sbjct: 5595 STVSQGFPHSEITTLRSRTPGD--VSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPES 5652

Query: 245  VPQSPIP-------PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQ 297
            +P SP+P        L+   N+L    P    +   N S+    ++      A T+A   
Sbjct: 5653 IPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEA--- 5709

Query: 298  SIIHKFLTAGPSAFNI-TSLISQAAQLSTQAQPSNQ---SPMSL------TSDASSPRSY 347
              +H  +    +  N+ TS+    +Q S  A        SPM +      TS ++S  ++
Sbjct: 5710 --MHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPAF 5767

Query: 348  VSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPV 407
               RI T  T+        S  P     + S  +      S   ++ P T   +     V
Sbjct: 5768 FETRIQTESTS--------SLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEV 5819

Query: 408  SPRSLQRSSSQRSPSPGPNHTSNSSNASNATV 439
                    +S R+   GP+H+  S   S  T+
Sbjct: 5820 -------ITSSRTTISGPDHSKMSPYISTETI 5844



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 62/291 (21%), Positives = 109/291 (37%), Gaps = 37/291 (12%)

Query: 192   MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 251
             M    T  F+  KS   D  +  + T+P   ++S ++ T+  P  +  V  S VP S   
Sbjct: 11501 MVPRTTPKFSHSKS---DTTLPVAITSPGPEASSAVSTTTISPDMSDLV-TSLVPSSGTD 11556

Query: 252   PLLQDPNLLRQLL-PALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSA 310
                  P L      P   AT   + +           T+     ++ +  H+     PS 
Sbjct: 11557 TSTTFPTLSETPYEPETTATWLTHPAE----------TSTTVSGTIPNFSHRGSDTAPSM 11606

Query: 311   FNITSLISQAAQLSTQAQPS-----NQSPMSLTSDASSPRSYVSPRISTPQTN------- 358
                  + +++   +T   PS          S  +D S+    ++P    P+T        
Sbjct: 11607 VTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHP 11666

Query: 359   ------TVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSL 412
                   TVPI+ + S+ P +    V+ P     PVS++ +    ++         SPR+ 
Sbjct: 11667 GTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTE 11726

Query: 413   QRSSSQRSPSPG-PNHTSN---SSNASNATVVPQNSSARSTCSLTPALAAH 459
               S+   + SPG P   ++   SS A+ +T VP  + +      T  L+ H
Sbjct: 11727 ASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHSPGMPETTALLSTH 11777



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 62/264 (23%), Positives = 93/264 (35%), Gaps = 44/264 (16%)

Query: 195  TATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLL 254
            T+T+ F SG  ++     SHS  T   S   G  P  + P+   A  VS    S      
Sbjct: 8514 TSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSS------ 8567

Query: 255  QDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNIT 314
                      PA+ +T   +     IS     +TA              LT GP     T
Sbjct: 8568 ----------PAMTSTSFFSTLPESISSSPHPVTA-------------LLTLGP--VKTT 8602

Query: 315  SLISQAAQLSTQAQP---SNQSPMSLTSDASSPRSYVSPRISTPQTN--TVPIKPLISTP 369
             ++  +++  T + P   S  + +  TS+ +  R  + P  +TP  N  TV  K L    
Sbjct: 8603 DMLRTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHL---- 8658

Query: 370  PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTS 429
               S   V   +V   P S  AT   +         P  P ++    +  S + G    S
Sbjct: 8659 ---SPSSVLADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTS-SLTSGLREIS 8714

Query: 430  NSSNASNATVVPQNSSARSTCSLT 453
             S   S+AT    + S   T + T
Sbjct: 8715 TSQETSSATERSASLSGMPTGATT 8738



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 46/228 (20%), Positives = 91/228 (39%), Gaps = 20/228 (8%)

Query: 225  SGLNPTSAPPTSASAVPVS-PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKI 283
            SG +P S   TS+S+  +S P   SP P     P  L +  P+    L    ++  +   
Sbjct: 6498 SGTSPPSVEKTSSSSSLLSLPAITSPSPV----PTTLPESRPSSPVHLTSLPTSGLVKTT 6553

Query: 284  NEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASS 343
            + + + A    +L S  HK  T      +   +        T    +     S +S    
Sbjct: 6554 DMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSS---V 6610

Query: 344  PRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV------STPVVKQGPVSQSATQQPVT 397
            P     P++++P   +  I+  I +  +    ++      ST  +  G    S +Q P+ 
Sbjct: 6611 PAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIV 6670

Query: 398  ADKQQG--HEPVSPRS----LQRSSSQRSPSPGPNHTSNSSNASNATV 439
            + ++    H+  +  +     + +SS+R+  PGP+H++ S + S   +
Sbjct: 6671 STEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHSTESPDISTEVI 6718



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 69/269 (25%), Positives = 110/269 (40%), Gaps = 39/269 (14%)

Query: 186  DYRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPV 245
            D  +  M    TSG+     +S    ++ S TT +TSS     PT       S    S  
Sbjct: 9219 DTEKLEMTNVVTSGYTHESPSS---VLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDT 9275

Query: 246  PQSPIPPLLQDPNLLRQLLPALQATL---QLNNSNVDISKINEVLTAAVTQASLQSIIHK 302
             +      +Q  + L  L P L  T    + +++    + ++ V T A T+ S    I  
Sbjct: 9276 SR------IQTKSKL-SLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAISS 9328

Query: 303  FLTA--GPSAFNITSLISQAA--QLSTQAQPSNQSPMSLT-----SDASSPRSYVSPRIS 353
              T+  GP+   ++S  S     ++ST       + M++T     S A+S  ++     S
Sbjct: 9329 SRTSIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSS 9388

Query: 354  T---PQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPR 410
            T   P T++       +T     Q  V+TP+  +GP   S    P++ +K        P 
Sbjct: 9389 TASWPGTHS-------ATTQRFPQSVVTTPM-SRGPEDVS-WPSPLSVEKNS-----PPS 9434

Query: 411  SLQRSSSQRSPSPGPNHTSNSSNASNATV 439
            SL  SSS  SPSP  +  S SS++S   V
Sbjct: 9435 SLVSSSSVTSPSPLYSTPSGSSHSSPVPV 9463



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 78/338 (23%), Positives = 121/338 (35%), Gaps = 40/338 (11%)

Query: 80   NVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN--PSKTSDAPYDSADDWSE 137
            N  T    E    T+     + H    LHSS S  S PS +  P  T     D+    S 
Sbjct: 6001 NTETIHFSENTAETNMGTTNSMHK---LHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTST 6057

Query: 138  HISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKM--AVNSFPKDRDYRREVMQAT 195
              S   K    +  + ++   K            E+N +  +V+        R EV    
Sbjct: 6058 PGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYD 6117

Query: 196  ATSGFASGKST-----SGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPI 250
             T   AS +ST     S +   SHS + P T S      T   P+  +++    +  S I
Sbjct: 6118 PTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTI 6177

Query: 251  PPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSA 310
                  P+   Q     + T  +NN   D+ K +    +A    SL S     +T  PS 
Sbjct: 6178 ATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPF--SAEEANSLSSQAPLLVTTSPSP 6235

Query: 311  FNIT-------SLIS----------QAAQLSTQAQPSNQSPMSL-----TSDASSPRSYV 348
               T       SL+S          +   + T  +P  +SP +L     TS+A++    +
Sbjct: 6236 VTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTM 6295

Query: 349  SPRISTPQTN----TVPIKPLISTPPVSSQPKVSTPVV 382
             P I+T   N    + P +   +  P S   K ++ VV
Sbjct: 6296 HPSINTAVANVGTTSSPNEFYFTVSPDSDPYKATSAVV 6333



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 54/263 (20%), Positives = 102/263 (38%), Gaps = 23/263 (8%)

Query: 205   STSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPV-PQSPIPPLLQDPNLLRQL 263
             S+ G   +  S  T  TSSA   +P   P +  + +PV  + P +  P + +   +    
Sbjct: 10188 SSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITS-- 10245

Query: 264   LPALQATLQLNNS----NVDISKINEVLTAAVTQASLQSIIHKFLTAG-PSAFNITSLIS 318
              P  + T+ +  S    + D+    E ++      SL   +  F T G P A  I+   S
Sbjct: 10246 FPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRA--ISGSGS 10303

Query: 319   QAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVS 378
               ++  +    +  S ++ +  +S+P  + S   +T  ++T+P    I T   ++  +V 
Sbjct: 10304 PFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEI-TSSSATPYRVD 10362

Query: 379   TPVVKQGPVSQSATQQPVTAD--KQQGHEPVSPRSLQR----------SSSQRSPSPGPN 426
             T +  +   ++       T D   Q G    SP    R          +S+ + PS    
Sbjct: 10363 TSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTR 10422

Query: 427   HTSNSSNASNATVVPQNSSARST 449
              T       + T +P  ++ R T
Sbjct: 10423 LTRTDGIMEHITKIPNEAAHRGT 10445



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 52/243 (21%), Positives = 100/243 (41%), Gaps = 29/243 (11%)

Query: 217   TTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNS 276
             TTPS +++ G   +SA PT      VSP     + PL+      R +       L L++S
Sbjct: 11069 TTPSMATSHGAEASSAVPTPT----VSPGVSGVVTPLVTSS---RAVTSTTIPILTLSSS 11121

Query: 277   NVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN-ITSLISQAAQLSTQAQPSNQSPM 335
               + +    + T+   +AS        LT  P     +TSL++ +  +++   P      
Sbjct: 11122 EPETTP--SMATSHGVEAS-----SAVLTVSPEVPGMVTSLVTSSRAVTSTTIP------ 11168

Query: 336   SLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQS----- 390
             +LT  +  P +  S  ++  +   +   P ++  P + Q  V++ V   G  + +     
Sbjct: 11169 TLTISSDEPETTTS-LVTHSEAKMISAIPTLAVSP-TVQGLVTSLVTSSGSETSAFSNLT 11226

Query: 391   -ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARST 449
              A+ QP T D    H      S+  + +  +  P  N +  +  A +++ +P+ +S  S 
Sbjct: 11227 VASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSH 11286

Query: 450   CSL 452
               L
Sbjct: 11287 SEL 11289



 Score = 32.7 bits (73), Expect = 0.87
 Identities = 59/270 (21%), Positives = 106/270 (39%), Gaps = 38/270 (14%)

Query: 195   TATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLL 254
             T++S   S  S   D   +   T PS    S ++ T+   ++ +      +P  P     
Sbjct: 9819  TSSSVHESHSSVLADSETT--ITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPT---- 9872

Query: 255   QDPNLLRQLLPALQATLQLNNSNVDISKINEVL----TAAVTQASLQSIIHKFLTAGPSA 310
                     L P  + T   +     I++ + VL    T+A T+ S+  I+       P +
Sbjct: 9873  ------FSLTPGFRET-STSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDS 9925

Query: 311   FNIT---SLISQA-AQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLI 366
                T    +I++   +LS+ +  S  + M++T+  SSP +     + T  T T P+    
Sbjct: 9926  DQSTMSPDIITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTL-TLATTTAPLARTH 9984

Query: 367   STPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPN 426
             ST P        T ++ + P + S                 S   ++++SS  S    P 
Sbjct: 9985  STVPPRFLHSEMTTLMSRSPENPSWK---------------SSLFVEKTSSSSSLLSLPV 10029

Query: 427   HTSNSSNASNATVVPQNSSARSTCSLTPAL 456
              TS S +++    +P +SS   T  LTP +
Sbjct: 10030 TTSPSVSSTLPQSIP-SSSFSVTSLLTPGM 10058



 Score = 32.7 bits (73), Expect = 0.87
 Identities = 43/190 (22%), Positives = 67/190 (35%), Gaps = 21/190 (11%)

Query: 196   ATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQ 255
             A SG +S   T+       S  T ++ S + + P     T           + P PP   
Sbjct: 11898 AVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTS 11957

Query: 256   -----DPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSA 310
                   P  + +        L    S+  ++K     T         S+     T G S 
Sbjct: 11958 HGEGVSPTTILRTTMVEATNLATTGSSPTVAK-----TTTTFNTLAGSLFTPLTTPGMST 12012

Query: 311   FNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPP 370
                 S+ S+ +        +++S +S TS  S  R Y +P  STP T+T    P IST  
Sbjct: 12013 LASESVTSRTSY-------NHRSWISTTS--SYNRRYWTPATSTPVTST--FSPGISTSS 12061

Query: 371   VSSQPKVSTP 380
             + S    + P
Sbjct: 12062 IPSSTAATVP 12071



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 33/141 (23%), Positives = 59/141 (41%), Gaps = 9/141 (6%)

Query: 322   QLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST--------PQTNTVPIKPLISTPPVSS 373
             + +T A  +  + +  TS A+   S  +P + T           +T+P + +I+TP V  
Sbjct: 10473 ETTTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFP 10532

Query: 374   QPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSL-QRSSSQRSPSPGPNHTSNSS 432
                 +T  +     ++++T  P T       E  +  SL  RS ++RSP       S+S 
Sbjct: 10533 DVPETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSE 10592

Query: 433   NASNATVVPQNSSARSTCSLT 453
               + A+ V   +    T S T
Sbjct: 10593 PDTTASWVIHPAETIPTVSKT 10613



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 65/308 (21%), Positives = 120/308 (38%), Gaps = 48/308 (15%)

Query: 210  KPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQA 269
            +P     ++P+T+S S ++ T     S+S +PV+ +  S +        L +   P   +
Sbjct: 7969 RPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTD--MLHKSSEPVTNS 8026

Query: 270  TLQLNNSNVDISKINEVLT-AAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 328
               L++++V+I   +EV T    T  S    +    T+  S    TS +   +Q S    
Sbjct: 8027 PANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSS-SGHESTSFVLADSQTSKVT- 8084

Query: 329  PSNQSPMSLTS-------DASSPRSYVSPRISTPQTNTVPI-----------------KP 364
                SPM +TS         S+P  + + RI T  T+++ +                   
Sbjct: 8085 ----SPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMST 8140

Query: 365  LISTPPVSSQPKVS-TPVVKQGPVSQSA----TQQPVTADKQQGHEPVSPRSLQRSSSQ- 418
            ++S  P  +  +VS T V      S S     T  P T+ +     P S  S+   S++ 
Sbjct: 8141 VLSGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPETSTETITRLPTS--SIMTESAEM 8198

Query: 419  --RSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQG---WPA 473
              ++ +  P  T  S++  + +  P      ST  +T   +      L+    G   WP+
Sbjct: 8199 MIKTQTDPPGSTPESTHTVDISTTPNWVETHST--VTQRFSHSEMTTLVSRSPGDMLWPS 8256

Query: 474  DHAEKQAS 481
              + ++ S
Sbjct: 8257 QSSVEETS 8264



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 53/279 (18%), Positives = 101/279 (36%), Gaps = 16/279 (5%)

Query: 94   SYSPQENSHNHSALHSSNSHSSNPS-NNPSKTSDAPYDSADDW--SEHISSSGKKYYYNC 150
            SY+P       + +H S +  +  S ++P  T+    ++   W  + +I+++  K   + 
Sbjct: 1277 SYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSA 1336

Query: 151  RTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGKSTSGDK 210
            +       +     E   + + A   A +  PK        + + AT  +    +T    
Sbjct: 1337 QVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPN--LTSPATKAWTITDTTEHST 1394

Query: 211  PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQD-PNLLRQLLPALQA 269
             + +   T     +SG    SAP   +  +P SP   S    L  D P     L P+ Q 
Sbjct: 1395 QLHY---TKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQT 1451

Query: 270  TLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQP 329
            T+ L  +    + + E + +     S  S       +  S F I   +S  +   ++++ 
Sbjct: 1452 TITLPMATWLSTSLTEEMASTDLDISSPS-------SPMSTFAIFPPMSTPSHELSKSEA 1504

Query: 330  SNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLIST 368
               +  +  S        +     T    TVPI PL +T
Sbjct: 1505 DTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTT 1543



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 67/284 (23%), Positives = 107/284 (37%), Gaps = 41/284 (14%)

Query: 189 REVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTS-----APPTSASAVPVS 243
           RE+    +TSG  S  + +         TT STS AS     S     + P     V  S
Sbjct: 481 RELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETS 540

Query: 244 PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF 303
           P  ++  PP     ++   +  ++ + +    S     K +      + + S  ++I + 
Sbjct: 541 PSMKTERPP--ASTSVAAPITTSVPSVV----SGFTTLKTSSTKGIWLEETSADTLIGE- 593

Query: 304 LTAGPSA--FNITSLISQ-----------AAQLSTQAQPSNQSPMSLTSDASSPRSYVSP 350
            TAGP+   F + + IS               L T+A  S+++   LT   +     VSP
Sbjct: 594 STAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSP 653

Query: 351 RISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPR 410
            +S             S+PP  ++P   T V    P + S            G  P++ R
Sbjct: 654 AVSKTAAG--------SSPPGGTKPSY-TMVSSVIPETSSLQSSAFREGTSLGLTPLNTR 704

Query: 411 SLQRSSSQRSPSPGPNHTSNSSN---ASNATVVPQNSSARSTCS 451
                SS    S G  HT  S++    S+A+V+    SA ST S
Sbjct: 705 --HPFSSPEPDSAG--HTKISTSIPLLSSASVLEDKVSATSTFS 744



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 4/114 (3%)

Query: 190   EVMQATATSGFASGKSTSGDKPVSHSCTT----PSTSSASGLNPTSAPPTSASAVPVSPV 245
             +V + TA+     G  TS   P   + +      + +S   L+PT++P  SA   P+S  
Sbjct: 11794 QVSETTASLTIRPGAETSTALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTH 11853

Query: 246   PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSI 299
             P +    ++    L   LL         +++    S +   ++ AV+  S  SI
Sbjct: 11854 PGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASI 11907


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 60/238 (25%), Positives = 107/238 (44%), Gaps = 39/238 (16%)

Query: 191  VMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSA--SAVPVSPVPQS 248
            +M  + T   +S  ST    PV  S  TP T+S+    PT++ PT+A  +++P S   + 
Sbjct: 3462 IMPLSTTPVASSEASTLSTTPVDTS--TPVTTSS----PTNSSPTTAEVTSMPTSTAGEG 3515

Query: 249  PIPPLLQDPNLLRQLLPALQATLQLN--NSNVDISKINEVLTAAVTQASLQSIIHKFLTA 306
              P L   P     +  +  +TL     +SN  ++  ++   A+ + A+LQ    +  T 
Sbjct: 3516 STP-LTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQ---ASSSPATLQVTTMRMSTP 3571

Query: 307  GPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLI 366
               + ++T+++  +  +++       S  S  S  S  RS  +P  ++ Q+N+ P  P +
Sbjct: 3572 SEGSSSLTTMLLSSTYVTS-------SEASTPSTPSVDRS--TPVTTSTQSNSTPTPPEV 3622

Query: 367  STPPVSSQPKVSTPVVKQGPVSQSA---------------TQQPVTADKQQGHEPVSP 409
             T P+S+  +VSTP+    PVS ++               T  PV    Q    PV+P
Sbjct: 3623 ITLPMSTPSEVSTPLTIM-PVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTP 3679



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 64/260 (24%), Positives = 112/260 (43%), Gaps = 50/260 (19%)

Query: 213  SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ 272
            + + ++P+T+  + + PTS P  +++ +   PV  +P+               A      
Sbjct: 2786 TEASSSPTTAEVTSM-PTSTPSETSTPLTSMPVNHTPV---------------ASSEAGT 2829

Query: 273  LNNSNVDIS-KINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSL--------ISQAAQL 323
            L+ + VD S  +     A+ +  + + I+    TA   +  +TS+         S+A+ L
Sbjct: 2830 LSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTL 2889

Query: 324  STQAQPSNQSPMSLTSDASSPRSY--VSPRISTPQTNTVPIKP-LISTPPVS---SQPKV 377
            ST    ++    + T  +SSP +    S  ISTP   + P+   L+ST PV+   +    
Sbjct: 2890 STTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLS 2949

Query: 378  STPVVKQGPVSQS--ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNAS 435
            +TPV  + PV+ S  A+  P TA+                +S    +PG   T  +S   
Sbjct: 2950 TTPVDTRTPVTTSAEASSSPTTAE---------------GTSMPISTPGERRTPLTS--M 2992

Query: 436  NATVVPQNSSARSTCSLTPA 455
            + + +P  SS  ST S TPA
Sbjct: 2993 SVSTMPVASSEASTLSRTPA 3012



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 71/316 (22%), Positives = 125/316 (39%), Gaps = 34/316 (10%)

Query: 172  EANKMAVNSFPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTS 231
            E   M  +++ + R     +   T T   +S  ST    PV +S  TP T+S       S
Sbjct: 1676 EGTSMPTSTYTEGRTPLTSITVRT-TPVASSAISTLSTTPVDNS--TPVTTSTEA---RS 1729

Query: 232  APPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLN--NSNVDISKINEVLTA 289
            +P TS      +  P     PL   P     +L +  +TL     +++  ++   E  T+
Sbjct: 1730 SPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEA-TS 1788

Query: 290  AVTQASLQSIIHKFLTAGPSAFNITSLI------SQAAQLSTQAQPSNQSPMSLTSDASS 343
            + T A   SI    L+ G +    T +       S+A+ LST    SN   ++ T+ +SS
Sbjct: 1789 SPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSS 1848

Query: 344  PRSYVSPRISTPQTN-------TVPIKP----------LISTPPVSSQPKVSTPVVKQGP 386
            P       I+T   +       ++P+            L +TP V+S P  +   V   P
Sbjct: 1849 PTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSP 1908

Query: 387  VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA 446
             +   +  P T+  ++G  P++   +  +++  S       T+ +   +  T   Q SS+
Sbjct: 1909 TTADGSSMP-TSTPREGRPPLTSIPVS-TTTVASSEINTLSTTLADTRTPVTTYSQASSS 1966

Query: 447  RSTCSLTPALAAHFSE 462
             +T   T      +SE
Sbjct: 1967 PTTADGTSMPTPAYSE 1982



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 70/307 (22%), Positives = 118/307 (38%), Gaps = 47/307 (15%)

Query: 192  MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 251
            M  + T   +S  ST    PV  S  TP+T+S  G   +S+P T+      +  P     
Sbjct: 1990 MPLSTTLVVSSEASTLSTTPVDTS--TPATTSTEG---SSSPTTAGGTSIQTSTPSERTT 2044

Query: 252  PLLQDPNLLRQLLPALQATLQLN--NSNVDISKINEVLTAAVTQASLQSII-----HKFL 304
            PL   P     ++ +   TL     +S   ++   E  ++A  + S  +I         L
Sbjct: 2045 PLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLL 2104

Query: 305  TAGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDASSP-------------RSYVSP 350
            T+ P   + T + S +A+ LST    SN   ++ T  +SSP                 +P
Sbjct: 2105 TSIP--LSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTP 2162

Query: 351  RISTPQTNTV----PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEP 406
              S P + TV     I  L +TP  +S P  ++   +  P +   T  P T+   +G  P
Sbjct: 2163 LTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP-TSTPSEGSTP 2221

Query: 407  VSPRSLQ------RSSSQRSPSPGPNHT--------SNSSNASNATVVPQNSSARSTCSL 452
             +   +         +S  S +P    T        ++S   +  T +P ++ +  T  L
Sbjct: 2222 FTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPL 2281

Query: 453  TPALAAH 459
            T    +H
Sbjct: 2282 TSIPVSH 2288



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 54/238 (22%), Positives = 99/238 (41%), Gaps = 14/238 (5%)

Query: 221 TSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDI 280
           TS+ +  +PT+A  TS   +P S   +   P L   P     +  +  +TL +  + VD 
Sbjct: 308 TSTEASSSPTTAEGTS---IPTSTYTEGSTP-LTSTPASTMPVATSEMSTLSI--TPVDT 361

Query: 281 SKINEVLT---AAVTQASLQSIIHKFLTAGPSAFNITSL-ISQAAQLSTQAQPSNQSPMS 336
           S +    T   +  T A   S++   L+ G +   +T++ +S     S++A  ++  P+ 
Sbjct: 362 STLVTTSTEPSSLPTTAEATSMLTSTLSEGSTP--LTNMPVSTILVASSEASTTSTIPVD 419

Query: 337 LTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPV 396
             +  ++     S   +   T+     P   + P++S P  +TPV      + S T  PV
Sbjct: 420 SKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTT--PV 477

Query: 397 TADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +  Q      +  S   +     P+  P+  S    + + + +P  SS  ST S TP
Sbjct: 478 DSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTP 535



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 74/309 (23%), Positives = 117/309 (37%), Gaps = 50/309 (16%)

Query: 192 MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAP----PTSASAVPVSPVPQ 247
           M    T   +S  ST    PV  S T  +TS+ +  +PT+A     PTS  +   +P+  
Sbjct: 693 MPVNTTLVASSEASTLSTTPVDTS-TPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTS 751

Query: 248 SPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSII-----HK 302
            P+        LL     +  +T  L+ S    +      +   T+ +   I        
Sbjct: 752 MPV-----SKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSP 806

Query: 303 FLTAGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDASSPRS--------------- 346
            LT+ P   +IT + S +A+ LST    SN    + T  +SSP                 
Sbjct: 807 LLTSIP--VSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGR 864

Query: 347 --YVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGH 404
               S  +ST    T  I  L +TP  +S P  ++   +  P +   T  P T+   +G 
Sbjct: 865 TPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP-TSTPGEGS 923

Query: 405 EPVS--PRSLQR--SSSQRSPSPGPNHTS----------NSSNASNATVVPQNSSARSTC 450
            P++  P S     SS  R+ S  P  TS          +S   +  T +P ++ +  T 
Sbjct: 924 TPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTT 983

Query: 451 SLTPALAAH 459
            LT    +H
Sbjct: 984 PLTSTPVSH 992



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 66/277 (23%), Positives = 103/277 (37%), Gaps = 27/277 (9%)

Query: 197  TSGFASGKSTSGDKPVSHSCTTPSTSSASGLNP-------------TSAPPTSASAVPVS 243
            TS  + G +     PVSH+    S +S     P             +S PPT+      +
Sbjct: 975  TSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPT 1034

Query: 244  PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF 303
              P     PL + P  +   + A   T  L+ +  D S          +QAS  S     
Sbjct: 1035 STPSEGSTPLTRMP--VSTTMVASSETSTLSTTPADTS----TPVTTYSQASSSSTTADG 1088

Query: 304  LTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTS--DASSPRSYVSPRISTPQT---N 358
             +   S ++  S    +  +ST+   S+++    T+  D S P +  +   S+P T    
Sbjct: 1089 TSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGT 1148

Query: 359  TVPIKPLIS-TPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 417
            ++P  P    T P++S P  +T VV     + S T            E  SP      +S
Sbjct: 1149 SIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTS 1208

Query: 418  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
              + +PG   T  +S     T  P  SS  ST S +P
Sbjct: 1209 MPTSTPGERSTPLTSMPVRHT--PVASSEASTLSTSP 1243



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 68/311 (21%), Positives = 128/311 (41%), Gaps = 59/311 (18%)

Query: 197  TSGFASGKSTSGDKPVSHSCTTPSTSSASGLNP--TSAPPTSASAVPVSPVPQSPIPPLL 254
            TS  + GK+     PVS++    S +S     P  +++P  +++AV  SP P       +
Sbjct: 1447 TSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAI 1506

Query: 255  QDPNLLRQLLPALQATLQLNNSNVDISKINEVLTA-AVTQA------------------S 295
              P+     L     ++ ++ + V  S+IN + T  AVT                    S
Sbjct: 1507 STPSEGSTAL----TSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTS 1562

Query: 296  LQSIIHKFLTAGPSAFNITSLI---SQAAQLST-------QAQPSNQSPMSLTSDASSPR 345
            +Q+  +   +   ++  +++++   S+A  LST       Q   S ++  S T++ SS  
Sbjct: 1563 MQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMT 1622

Query: 346  ----SYVSPRISTPQTNTVPI-----KPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPV 396
                S  SP +++   +T P+       L +TP  S+ P +++  V   P     T  P 
Sbjct: 1623 ISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMP- 1681

Query: 397  TADKQQGHEPVSPRSLQRSS------SQRSPSPGPNHT--------SNSSNASNATVVPQ 442
            T+   +G  P++  +++ +       S  S +P  N T         +S   S  T +P 
Sbjct: 1682 TSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPN 1741

Query: 443  NSSARSTCSLT 453
            ++ +  T  LT
Sbjct: 1742 STPSEGTTPLT 1752



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 67/268 (25%), Positives = 111/268 (41%), Gaps = 57/268 (21%)

Query: 192  MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 251
            M  + T   +S  ST    PV  S T  +TS+ + L+PT+A  TS   +P S  P     
Sbjct: 3345 MSFSTTPVVSSEASTLSTTPVDTS-TPVTTSTEASLSPTTAEGTS---IPTSS-PSEGTT 3399

Query: 252  PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAF 311
            PL               A++ ++ + V  S++N + T  V   +L +   +  ++ P+  
Sbjct: 3400 PL---------------ASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTE-ASSSPTIA 3443

Query: 312  NITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPV 371
              TSL                 P S TS+ S+P S + P  +TP  ++      +ST PV
Sbjct: 3444 EGTSL-----------------PTSTTSEGSTPLS-IMPLSTTPVASSEA--STLSTTPV 3483

Query: 372  SSQPKVSTPVVKQGPVSQSATQQPV----TADKQQGHEPVS--------PRSLQRSSSQR 419
             +    STPV    P + S T   V    T+   +G  P++          S + S+   
Sbjct: 3484 DT----STPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLST 3539

Query: 420  SPSPGPNHTSNSSNASNATVVPQNSSAR 447
            +P       ++SS AS++    Q ++ R
Sbjct: 3540 TPVDSNTFVTSSSQASSSPATLQVTTMR 3567



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 70/271 (25%), Positives = 117/271 (43%), Gaps = 23/271 (8%)

Query: 192  MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 251
            M  + T   +S  ST    P+  S T  +TS+ +  +PT+   T  +++P+S  P    P
Sbjct: 752  MPVSKTLLTSSEASTLSTTPLDTS-THITTSTEASCSPTT---TEGTSMPIS-TPSEGSP 806

Query: 252  PLLQDPNLLRQLLPALQATLQLN--NSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
             L   P  +  +     +TL     +SN  ++   EV +++ T A   S+     + G +
Sbjct: 807  LLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEV-SSSPTPAEGTSMPTSTYSEGRT 865

Query: 310  AFNITSLISQAAQLSTQAQPSNQSPMSLTS-DASSPRSYVSPRISTPQTNTVPIKPLIST 368
               +TS+      ++T A     S +S T  D S+P +  +   S+P T+     P  ST
Sbjct: 866  P--LTSMPVSTTLVATSAI----STLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT-ST 918

Query: 369  P-----PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSP 423
            P     P++S P  +TPVV     + SAT    +       E  S  +    +S  + +P
Sbjct: 919  PGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTP 978

Query: 424  GPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
                T  +S   + T+V   +S  ST S TP
Sbjct: 979  SEGTTPLTSTPVSHTLVA--NSEASTLSTTP 1007



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 62/293 (21%), Positives = 109/293 (37%), Gaps = 57/293 (19%)

Query: 206 TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLP 265
           T G  P++ +  +    + S ++  S  P   S +  +    S +P   +  ++L   L 
Sbjct: 330 TEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLS 389

Query: 266 ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT------AGPSAFNITSLI-- 317
                L    +N+ +S I    + A T +++      F+T      + P+    TS+   
Sbjct: 390 EGSTPL----TNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATS 445

Query: 318 ---------------------SQAAQLSTQAQPSNQSPMSLTSDASSPRSYV--SPRIST 354
                                S+A+ LST    S     + T  +SSP +    S   ST
Sbjct: 446 TPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTST 505

Query: 355 PQTNTVPIKPL-ISTPPVSSQPK---------VSTPVVKQGPVSQSA---------TQQP 395
           P   + P+  + +ST PV+S             STPV      S S+         T  P
Sbjct: 506 PSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTP 565

Query: 396 VTADKQQGHEPVSPR---SLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 445
                   + PVS R   S + S++  +P+      + SS AS+++   + +S
Sbjct: 566 SEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTS 618



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 53/277 (19%), Positives = 106/277 (38%), Gaps = 18/277 (6%)

Query: 197  TSGFASGKSTSGDKPVSHSCTTPSTSSASGLNP--TSAPPTSASAVPVSPVPQSPIPPLL 254
            TS  + G +     PVSH+    S +S     P  +++P  +++AV  SP P        
Sbjct: 1800 TSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAT 1859

Query: 255  QDPNLLRQLLPALQATLQLNNSNVDISKINEVLTA-AVTQASLQSIIHKFLTAGPSAFNI 313
              P+     L     ++ ++ + V  S+ N + T  AVT   + +     +++ P+  + 
Sbjct: 1860 STPSEGSTAL----TSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQ--VSSSPTTADG 1913

Query: 314  TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 373
            +S+ +   +      P    P+S T+ ASS  + +S  ++  +T         S+P  + 
Sbjct: 1914 SSMPTSTPREGRP--PLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTAD 1971

Query: 374  QPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSN 433
               + TP   +G    ++     T         +S   +  S+   + + G +  + +  
Sbjct: 1972 GTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGG 2031

Query: 434  ASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQG 470
             S  T  P   +       TP      S  L+   +G
Sbjct: 2032 TSIQTSTPSERT-------TPLAGMPVSTTLVVSSEG 2061



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 61/248 (24%), Positives = 105/248 (42%), Gaps = 28/248 (11%)

Query: 213  SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ 272
            + + ++P+T+  + + PTS P    +  P++ +P S  P +  +   L    P   +T  
Sbjct: 2432 TEASSSPTTAEGTSI-PTSPPSEGTT--PLASMPVSTTPVVSSEAGTL-STTPVDTSTPM 2487

Query: 273  LNNSNVDISKIN-EVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-QAAQLSTQAQPS 330
              ++    S    E +   ++ AS  S +   LT+ P   + T + S +A+ LST    S
Sbjct: 2488 TTSTEASSSPTTAEDIVVPISTASEGSTL---LTSIP--VSTTPVASPEASTLSTTPVDS 2542

Query: 331  NQSPMSLTSDASSPRSY--VSPRISTPQTNTVPIKPLISTPPVSSQPKVST--PVVKQGP 386
            N   ++ T  +SS  S    S   ST    + P++ +    PVS++P  S+    +   P
Sbjct: 2543 NSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSM----PVSTKPLASSEASTLSTTP 2598

Query: 387  VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA 446
            V    T  PVT   +    P + +          P   P+  S S  +   + +P  SS 
Sbjct: 2599 VD---TSIPVTTSTETSSSPTTAKDTS------MPISTPSEVSTSLTSILVSTMPVASSE 2649

Query: 447  RSTCSLTP 454
             ST S TP
Sbjct: 2650 ASTLSTTP 2657



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 81/354 (22%), Positives = 135/354 (38%), Gaps = 57/354 (16%)

Query: 201  ASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +S  ST    PV  S    +++ AS  +PT+A  TS   +P SP P     PL   P   
Sbjct: 1115 SSEASTLSTTPVDTSIPVTTSTEASS-SPTTAEGTS---IPTSP-PSEGTTPLASMPVST 1169

Query: 261  RQLLPALQATLQLN--NSNVDISKINEVL----TAAVTQASLQS------------IIHK 302
              ++ +   TL     +S   ++   E      TA VT     +            + H 
Sbjct: 1170 TLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHT 1229

Query: 303  FLTAGPSAFNITSLISQAAQLSTQAQPSNQS--------PMSLTSDASSPRSYVSPRIST 354
             + +  ++   TS +  +  ++T A+ S+          P S TS+ S+  + +   +ST
Sbjct: 1230 PVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIP--VST 1287

Query: 355  PQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSP----R 410
                +     L++TP  +  P V++  V   P     T  P T+   +G  P++      
Sbjct: 1288 TLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMP-TSTYSEGRTPLTSIPVNT 1346

Query: 411  SLQRSS--SQRSPSPGPNHT--------SNSSNASNATVVPQNSSARSTCSLT--PALAA 458
            +L  SS  S  S +P  N T         +S   S  T +P ++ +  T  LT  P    
Sbjct: 1347 TLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTT 1406

Query: 459  HFSENLIKHVQGWPAD-------HAEKQASRLREEAHNMGTIHMSEICTELKNL 505
                +    +   P D        AE  +S    E  ++ T   SE  T LK++
Sbjct: 1407 PVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSI 1460



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 75/333 (22%), Positives = 123/333 (36%), Gaps = 53/333 (15%)

Query: 153  EVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGKSTSGDKPV 212
            EVS    P E            +  + S P +       + A++     S        PV
Sbjct: 1314 EVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNT-----TLVASSAISILSTTPVDNSTPV 1368

Query: 213  SHS---CTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQA 269
            + S   C++P+TS  + + P S P  S    P++ +P S  P +  + + L    P   +
Sbjct: 1369 TTSTEACSSPTTSEGTSM-PNSNP--SEGTTPLTSIPVSTTPVVSSEASTL-SATPVDTS 1424

Query: 270  TLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAF------NITSLISQAAQL 323
            T    ++           T++ T A   SI     + G +        N     S+A+ L
Sbjct: 1425 TPGTTSAEA---------TSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTL 1475

Query: 324  STQAQPSNQSPMSLTSDASSPRSY--VSPRISTPQ------------TNTVP---IKPLI 366
            ST    SN   ++ T+ +SSP      S  ISTP             T TV    I  L 
Sbjct: 1476 STTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLS 1535

Query: 367  STPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPR--------SLQRSSSQ 418
            +TP V+S P  +       P +   T    T+   +G  P++          S + ++  
Sbjct: 1536 TTPAVTSTPVTTYSQASSSPTTADGTSMQ-TSTYSEGSTPLTSLPVSTMLVVSSEANTLS 1594

Query: 419  RSPSPGPNHTSNSSNASNATVVPQNSSARSTCS 451
             +P       + S+ AS++T    +S   ST S
Sbjct: 1595 TTPIDSKTQVTASTEASSSTTAEGSSMTISTPS 1627



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 60/265 (22%), Positives = 113/265 (42%), Gaps = 27/265 (10%)

Query: 213  SHSCTTPSTSSASGLNPTSAP-----PTSASAVPVSPVPQSPIPPLLQDP----NLLRQL 263
            + + ++P+T+  + + P S P     P ++ +V   PV  S    L + P      +   
Sbjct: 2963 AEASSSPTTAEGTSM-PISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTS 3021

Query: 264  LPALQATLQLNNSNVDISKINEVLT--AAVTQASLQSIIHKFLTAGPSAFNITSLISQAA 321
              A  +      + + IS  +E  T   ++  ++    I +  T   +  +  S +  + 
Sbjct: 3022 TEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTST 3081

Query: 322  QLSTQAQPSNQS--PMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVST 379
            ++S+   P+  +  P+S  S+ S+P + V P  +TP T++  I  L +TP  +S P  ++
Sbjct: 3082 EVSSSPTPAEGTSMPISTYSEGSTPLTGV-PVSTTPVTSSA-ISTLSTTPVDTSTPVTTS 3139

Query: 380  PVVKQGPVSQSATQQPVTADKQQGHEPVS----PRSLQRSSSQRSPSPGPNHTS----NS 431
                  P +   T  P T+   +G  P++       L  SS   + S  P  TS     S
Sbjct: 3140 TEAHSSPTTSEGTSMP-TSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTS 3198

Query: 432  SNASNATVVPQNSSARSTCS--LTP 454
            + A+++T     S   ST S  +TP
Sbjct: 3199 TEATSSTTAEGTSIPTSTPSEGMTP 3223



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 82/336 (24%), Positives = 124/336 (36%), Gaps = 69/336 (20%)

Query: 179  NSFPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLN---------- 228
            NS P +       +  + T   +S  ST    PV  S  TP T+SA   +          
Sbjct: 1388 NSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTS--TPGTTSAEATSSPTTAEGISI 1445

Query: 229  PTSAPP---TSASAVPVS--PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKI 283
            PTS P    T   ++PVS  PV  S    L   P  +    P + +T   ++        
Sbjct: 1446 PTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTP--VDSNSPVVTSTAVSSSPTPAEGTS 1503

Query: 284  NEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMS-LTSDAS 342
              + T +    +L SI     T   S  N  SL +  A  ST     +Q+  S  T+D +
Sbjct: 1504 IAISTPSEGSTALTSIPVSTTTVASSEIN--SLSTTPAVTSTPVTTYSQASSSPTTADGT 1561

Query: 343  SPRSYVSPRISTPQTNTVPIKPL---------ISTPPVSSQ------------------- 374
            S ++      STP T ++P+  +         +ST P+ S+                   
Sbjct: 1562 SMQTSTYSEGSTPLT-SLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSS 1620

Query: 375  -----PKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGP---- 425
                 P   +P++   PVS +    P  +       PV   S   +S++ S SP P    
Sbjct: 1621 MTISTPSEGSPLLTSIPVSTTPVASPEASTLST--TPVDSNSPVITSTEVSSSPTPAEGT 1678

Query: 426  -----NHTSNSSNASNATV--VPQNSSARSTCSLTP 454
                  +T   +  ++ TV   P  SSA ST S TP
Sbjct: 1679 SMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTP 1714



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 59/257 (22%), Positives = 101/257 (39%), Gaps = 38/257 (14%)

Query: 201  ASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +S  ST    PV  S  TP T+S    + T+A  TS   +P S  P   + PL   P   
Sbjct: 3178 SSEDSTLSATPVDTS--TPVTTSTEATSSTTAEGTS---IPTS-TPSEGMTPLTSVP--- 3228

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQA 320
                        ++N+ V  S+ + + T  V   +  +   +  ++ P+A   +   S  
Sbjct: 3229 ------------VSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTP 3276

Query: 321  AQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTP 380
            ++ ST   P    P+S T+ ASS  S +S   +   T         S+PP++    + T 
Sbjct: 3277 SEGST---PLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTS 3333

Query: 381  VVKQGP---VSQSATQQPVTADKQQ--GHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNAS 435
               +G     + S +  PV + +       PV   +   +S++ S SP           +
Sbjct: 3334 TYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSP---------TTA 3384

Query: 436  NATVVPQNSSARSTCSL 452
              T +P +S +  T  L
Sbjct: 3385 EGTSIPTSSPSEGTTPL 3401



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 59/263 (22%), Positives = 104/263 (39%), Gaps = 33/263 (12%)

Query: 205  STSGDKPVSHSCTTPSTSSASGLNPTS---APPTSASAVPVSPVPQSPIPPLLQDPNLLR 261
            ST    PV  +    +++ AS   PT+   + PTS S+   +P+ + P+   +       
Sbjct: 2297 STLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMV------ 2350

Query: 262  QLLPALQATLQLNNSNVDISK-INEVLTAAVTQASLQSIIHKFLTAGPSAFNITSL-ISQ 319
                A   T  L+ +  D S  +     A  +  +         T    +  +TS+ +S 
Sbjct: 2351 ----ASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVST 2406

Query: 320  AAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQT---NTVPIKPLIS-TPPVSSQP 375
               +S++A   + +P+    D S+P +  +   S+P T    ++P  P    T P++S P
Sbjct: 2407 MPVVSSEASTHSTTPV----DTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMP 2462

Query: 376  KVSTPVV--KQGPVSQSA--TQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNS 431
              +TPVV  + G +S +   T  P+T   +    P +   +    S  S        S  
Sbjct: 2463 VSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEG------STL 2516

Query: 432  SNASNATVVPQNSSARSTCSLTP 454
              +   +  P  S   ST S TP
Sbjct: 2517 LTSIPVSTTPVASPEASTLSTTP 2539



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 77/303 (25%), Positives = 121/303 (39%), Gaps = 36/303 (11%)

Query: 180  SFPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPT---- 235
            S P +       M  ++T   +S  ST     V  S  TP T+S    N T  PP     
Sbjct: 3569 STPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRS--TPVTTSTQS-NSTPTPPEVITL 3625

Query: 236  -----SASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKIN-EVLTA 289
                 S  + P++ +P S     + +       LP   +T  + ++ V  S +  E  T 
Sbjct: 3626 PMSTPSEVSTPLTIMPVSTTSVTISEAGTA-STLPVDTSTPVITSTQVSSSPVTPEGTTM 3684

Query: 290  AVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQA----QPSNQSPMSLTSDASSPR 345
             +   S  S      T   S   +TS  S+ + LST +     P   S  +++S A+   
Sbjct: 3685 PIWTPSEGST--PLTTMPVSTTRVTS--SEGSTLSTPSVVTSTPVTTSTEAISSSATLDS 3740

Query: 346  SYVSPRISTP-QTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSAT------QQPVTA 398
            + +S  +S P + +T+    L+ST PV+  P+ STP +     S S T        P T 
Sbjct: 3741 TTMS--VSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTL 3798

Query: 399  DKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAA 458
            +      P+S  S +RS+   +    P    + S AS  +  P ++   ST  LT   A 
Sbjct: 3799 EGTT-TMPMSTTS-ERSTLLTTVLISPISVMSPSEASTLSTPPGDT---STPLLTSTKAG 3853

Query: 459  HFS 461
             FS
Sbjct: 3854 SFS 3856



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 68/278 (24%), Positives = 111/278 (39%), Gaps = 34/278 (12%)

Query: 203 GKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPV-SPVPQS-PIPPLLQDPNLL 260
           G S++   P     T+ STS ++ L P+S   TS+   P  + VP S P    +      
Sbjct: 104 GVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAF 163

Query: 261 RQL--LPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS 318
                LP+ +A   L    VD+S     LT + TQAS      +  T   S  +  S   
Sbjct: 164 VSTAPLPSFEAYTSL-TYKVDMS---TPLTTS-TQASSSPTTPESTTIPKSTNSEGSTPL 218

Query: 319 QAAQLSTQAQPSNQ------------SPMSLTSDA-SSPRSYVSPRI--STPQTNTVPI- 362
            +   ST    S++            +P+++++ A SSP +   P +  S P   + P+ 
Sbjct: 219 TSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLT 278

Query: 363 -KPLISTPPVSSQPKV--STPVVKQGPV--SQSATQQPVTADKQQGHEPVSPRSLQRSSS 417
             PL     VSS+     +TP     PV  S  A+  P TA+       +   +    S+
Sbjct: 279 RMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTS----IPTSTYTEGST 334

Query: 418 QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPA 455
             + +P       +S  S  ++ P ++S   T S  P+
Sbjct: 335 PLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPS 372



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 75/356 (21%), Positives = 134/356 (37%), Gaps = 56/356 (15%)

Query: 187 YRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVS-PV 245
           Y+ ++     TS  AS   T+ +     S T P ++++ G  P ++ P S   V  S  +
Sbjct: 180 YKVDMSTPLTTSTQASSSPTTPE-----STTIPKSTNSEGSTPLTSMPASTMKVASSEAI 234

Query: 246 PQSPIPPLLQDPNLLRQLLPALQATLQ---LNNS-----NVDISKIN-EVLTAAVTQASL 296
                P  +  P  +     +   T +   L+NS     +  ++++   V+    ++AS 
Sbjct: 235 TLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEAST 294

Query: 297 QSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYV---SPRIS 353
                  L+  P+A NI  + S  A  S         P S  ++ S+P +     +  ++
Sbjct: 295 -------LSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVA 347

Query: 354 TPQTNTVPIKPL------------ISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQ 401
           T + +T+ I P+             S P  +    + T  + +G  S   T  PV+    
Sbjct: 348 TSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEG--STPLTNMPVSTILV 405

Query: 402 QGHE-------PVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARST---CS 451
              E       PV  ++   ++S+ S SP     + + + S AT  P   S   T    S
Sbjct: 406 ASSEASTTSTIPVDSKTFVTTASEASSSP-----TTAEDTSIATSTPSEGSTPLTSMPVS 460

Query: 452 LTPALAAHFSENLIKHVQG--WPADHAEKQASRLREEAHNMGTIHMSEICTELKNL 505
            TP  ++  S      V          E  +S    E ++M T   SE  T L ++
Sbjct: 461 TTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSM 516



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 70/366 (19%), Positives = 131/366 (35%), Gaps = 45/366 (12%)

Query: 180  SFPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSA-----PP 234
            S P +       M    T   +S   T    PV  S T  +TS+ +  +PT+A     P 
Sbjct: 2803 STPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTS-TPVTTSTKASSSPTTAEGIVVPI 2861

Query: 235  TSAS-------AVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVL 287
            ++AS       ++PVS  P +           +   +P   +T   ++          + 
Sbjct: 2862 STASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIS 2921

Query: 288  TAAVTQASLQSIIHKFL-TAGPSAFNITSL-------ISQAAQLSTQAQPSNQSPMSLTS 339
            T +     L SI+   +  AG  A  +++        ++ +A+ S+    +  + M +++
Sbjct: 2922 TPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPIST 2981

Query: 340  DASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTAD 399
                     S  +ST    +     L  TP  +S P  ++      P +   T  P++  
Sbjct: 2982 PGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPIST- 3040

Query: 400  KQQGHEPV-------SPRSLQRSSS-------QRSPSPGPNHTSNSSNASNATVVPQNSS 445
              +G  P+       +P ++  +S+         SP       S+S   +  T +P ++ 
Sbjct: 3041 PSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTY 3100

Query: 446  ARSTCSLT--PALAAHFSENLIKHVQGWPAD-------HAEKQASRLREEAHNMGTIHMS 496
            +  +  LT  P      + + I  +   P D         E  +S    E  +M T   S
Sbjct: 3101 SEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPS 3160

Query: 497  EICTEL 502
            E  T L
Sbjct: 3161 EGSTPL 3166



 Score = 32.7 bits (73), Expect = 0.87
 Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 7/101 (6%)

Query: 173  ANKMAVNSFPKDRDYRREVMQATATSGFAS-GKSTSGDKPVSHSCTTPSTSSASGLNPTS 231
            ++     SF   +++    M   A   + +   + S  +  S  CTT    SAS L+ TS
Sbjct: 3977 SSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTT----SASTLSATS 4032

Query: 232  APPTSASAV--PVSPVPQSPIPPLLQDPNLLRQLLPALQAT 270
             P TS S    PV+P  +S  P  +    +     PA  +T
Sbjct: 4033 TPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSST 4073



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 49/268 (18%), Positives = 104/268 (38%), Gaps = 11/268 (4%)

Query: 193 QATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPP 252
           Q T ++  +S   T+    +  S  +  ++  + ++ ++ P  S+ A  +S  P     P
Sbjct: 482 QVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTP 541

Query: 253 LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 312
           +                ++  +  +   + +  +  +     S ++       A  + F 
Sbjct: 542 VTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFV 601

Query: 313 ITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVS 372
            TS  S+A+  ST A+ ++  P S  S+  +  +  S  +ST    +     L +TP  S
Sbjct: 602 TTS--SEASSSSTTAEGTSM-PTSTYSERGT--TITSMSVSTTLVASSEASTLSTTPVDS 656

Query: 373 SQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSP----RSLQRSSSQRSPSPGPNHT 428
           + P  ++        +   T  P T+   +G  P++      +L  SS   + S  P  T
Sbjct: 657 NTPVTTSTEATSSSTTAEGTSMP-TSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDT 715

Query: 429 SNS-SNASNATVVPQNSSARSTCSLTPA 455
           S   + ++ A+  P  +   S  + TP+
Sbjct: 716 STPVTTSTEASSSPTTADGASMPTSTPS 743


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 55/263 (20%), Positives = 94/263 (35%), Gaps = 35/263 (13%)

Query: 205  STSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPV------------SPVPQSPIPP 252
            +T+   P+S + T P T++ S    T +PPT+  + P             SP   +PI P
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1510

Query: 253  LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 312
                  L     P+   T     +    +  +   T  +T  +  + +    T  P    
Sbjct: 1511 PASTTTLPPTTTPSPPTT--TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568

Query: 313  ITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVS 372
             T+        +T + P+  +P   T   ++P    +P   T  T T P       P  +
Sbjct: 1569 TTT----PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP-------PTTT 1617

Query: 373  SQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
              P  +TP+    P + + T  P T           P +        +PSP P  T+ S 
Sbjct: 1618 PSPPTTTPIT---PPTSTTTLPPTTTPSP------PPTTTTTPPPTTTPSP-PTTTTPSP 1667

Query: 433  NASNATVVPQNSSARSTCSLTPA 455
              +  T  P  ++  S  + TP+
Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPS 1690



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 55/270 (20%), Positives = 98/270 (36%), Gaps = 28/270 (10%)

Query: 205  STSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLL 264
            +T+   P + + T P T++ S   PT+ P T  ++    P   +P PP            
Sbjct: 1520 TTTPSPPTTTTTTPPPTTTPSP--PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577

Query: 265  PALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLS 324
            P+   T   +   +  +      T +    +  +       + P+   IT         S
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP------PTS 1631

Query: 325  TQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLIST--PPVSSQPKVSTPVV 382
            T   P   +P    +  ++P    +P   +P T T P  P+ +T  PP ++ P       
Sbjct: 1632 TTTLPPTTTPSPPPTTTTTPPPTTTP---SPPTTTTPSPPITTTTTPPPTTTPSSPITTT 1688

Query: 383  KQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP------SPGPNHTSNSSNASN 436
               P +   T  P T        P++  +   S++  SP      +P P  T +    + 
Sbjct: 1689 PSPPTTTMTTPSPTTTPS----SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM 1744

Query: 437  ATVVPQNSSARSTC-----SLTPALAAHFS 461
             T+ P  +S+  T      S+TP   + FS
Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSITPPTFSPFS 1774



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 53/264 (20%), Positives = 92/264 (34%), Gaps = 30/264 (11%)

Query: 205  STSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLL 264
            +T    P S +   P+T+ +     T+ PP + +  P      +P P     P +     
Sbjct: 1404 TTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTT 1463

Query: 265  PALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLS 324
            P    T      +   +  +   T      +  +      T  P     T+ I+  A  +
Sbjct: 1464 PPPTTT-----PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPT---TTPITPPASTT 1515

Query: 325  TQAQPSNQSPMSLTSDASSPRSYVSPRISTPQT----------NTVPIKP--LISTPPVS 372
            T    +  SP + T+    P +  SP  +TP T           T P  P    +TPP +
Sbjct: 1516 TLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1575

Query: 373  SQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
            + P   T      P   + T  P T          SP +   ++   + +P P  T+  +
Sbjct: 1576 TTPSPPTTTTPSPPTITTTTPPPTTTP--------SPPTTTTTTPPPTTTPSPPTTTPIT 1627

Query: 433  NASNATVVPQNS--SARSTCSLTP 454
              ++ T +P  +  S   T + TP
Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTP 1651



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 54/270 (20%), Positives = 101/270 (37%), Gaps = 33/270 (12%)

Query: 205  STSGDKPVSHSCTTPSTSSASG--LNPTSAPPTSASAVPVS-----PVPQSPIPPLLQDP 257
            +T+   P + + T P T++ S      T+ PPT+  + P+S     P   +P PP     
Sbjct: 1419 TTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPS 1478

Query: 258  NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI 317
                   P    T     +    +  +   T  +T  +  + +    T  P     T+  
Sbjct: 1479 PPTTTPSPPTTTT----TTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTT-- 1532

Query: 318  SQAAQLSTQAQPSNQSPMSLTSDASS--PRSYVSP---RISTPQTNTVPIKPLISTP--- 369
                  +T   P   +P++  +  ++  P +  SP     +TP   T P  P  +TP   
Sbjct: 1533 ---PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1589

Query: 370  --PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 427
                ++ P  +TP     P + + T  P T        P++P +   ++   + +P P  
Sbjct: 1590 TITTTTPPPTTTP---SPPTTTTTTPPPTTTPSPPTTTPITPPT-STTTLPPTTTPSPPP 1645

Query: 428  TSNSSNASNATVVPQNSSARS---TCSLTP 454
            T+ ++     T  P  ++  S   T + TP
Sbjct: 1646 TTTTTPPPTTTPSPPTTTTPSPPITTTTTP 1675



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 53/262 (20%), Positives = 95/262 (36%), Gaps = 35/262 (13%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P     P        
Sbjct: 2075 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2134

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-Q 319
              + P    T     +   I+    V T   T    Q+         P+   IT+  +  
Sbjct: 2135 TTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVT 2184

Query: 320  AAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
                 T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q  
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTP 2241

Query: 377  VSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
             +TP+     V    + + TQ P T        P++      +++  +P+P P  T   +
Sbjct: 2242 TTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPT 2288

Query: 433  NASNATVVPQNSSARSTCSLTP 454
                 T      +   T + TP
Sbjct: 2289 TTPITTTTTVTPTPTPTGTQTP 2310



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 53/262 (20%), Positives = 95/262 (36%), Gaps = 35/262 (13%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P     P        
Sbjct: 2282 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2341

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-Q 319
              + P    T     +   I+    V T   T    Q+         P+   IT+  +  
Sbjct: 2342 TTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVT 2391

Query: 320  AAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
                 T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q  
Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTP 2448

Query: 377  VSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
             +TP+     V    + + TQ P T        P++      +++  +P+P P  T   +
Sbjct: 2449 TTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPT 2495

Query: 433  NASNATVVPQNSSARSTCSLTP 454
                 T      +   T + TP
Sbjct: 2496 TTPITTTTTVTPTPTPTGTQTP 2517



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 53/262 (20%), Positives = 95/262 (36%), Gaps = 35/262 (13%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P     P        
Sbjct: 2489 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2548

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-Q 319
              + P    T     +   I+    V T   T    Q+         P+   IT+  +  
Sbjct: 2549 TTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVT 2598

Query: 320  AAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
                 T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q  
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTP 2655

Query: 377  VSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
             +TP+     V    + + TQ P T        P++      +++  +P+P P  T   +
Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPT 2702

Query: 433  NASNATVVPQNSSARSTCSLTP 454
                 T      +   T + TP
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQTP 2724



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 53/262 (20%), Positives = 95/262 (36%), Gaps = 35/262 (13%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P     P        
Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2755

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-Q 319
              + P    T     +   I+    V T   T    Q+         P+   IT+  +  
Sbjct: 2756 TTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVT 2805

Query: 320  AAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
                 T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q  
Sbjct: 2806 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTP 2862

Query: 377  VSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
             +TP+     V    + + TQ P T        P++      +++  +P+P P  T   +
Sbjct: 2863 TTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPT 2909

Query: 433  NASNATVVPQNSSARSTCSLTP 454
                 T      +   T + TP
Sbjct: 2910 TTPITTTTTVTPTPTPTGTQTP 2931



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 53/262 (20%), Positives = 95/262 (36%), Gaps = 35/262 (13%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P     P        
Sbjct: 2903 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2962

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-Q 319
              + P    T     +   I+    V T   T    Q+         P+   IT+  +  
Sbjct: 2963 TTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVT 3012

Query: 320  AAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
                 T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q  
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTP 3069

Query: 377  VSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
             +TP+     V    + + TQ P T        P++      +++  +P+P P  T   +
Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPT 3116

Query: 433  NASNATVVPQNSSARSTCSLTP 454
                 T      +   T + TP
Sbjct: 3117 TTPITTTTTVTPTPTPTGTQTP 3138



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 53/262 (20%), Positives = 95/262 (36%), Gaps = 35/262 (13%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P     P        
Sbjct: 3110 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3169

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-Q 319
              + P    T     +   I+    V T   T    Q+         P+   IT+  +  
Sbjct: 3170 TTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVT 3219

Query: 320  AAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
                 T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q  
Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTP 3276

Query: 377  VSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
             +TP+     V    + + TQ P T        P++      +++  +P+P P  T   +
Sbjct: 3277 TTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPT 3323

Query: 433  NASNATVVPQNSSARSTCSLTP 454
                 T      +   T + TP
Sbjct: 3324 TTPITTTTTVTPTPTPTGTQTP 3345



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 53/262 (20%), Positives = 95/262 (36%), Gaps = 35/262 (13%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P     P        
Sbjct: 3317 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3376

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-Q 319
              + P    T     +   I+    V T   T    Q+         P+   IT+  +  
Sbjct: 3377 TTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVT 3426

Query: 320  AAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
                 T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q  
Sbjct: 3427 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTP 3483

Query: 377  VSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
             +TP+     V    + + TQ P T        P++      +++  +P+P P  T   +
Sbjct: 3484 TTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPT 3530

Query: 433  NASNATVVPQNSSARSTCSLTP 454
                 T      +   T + TP
Sbjct: 3531 TTPITTTTTVTPTPTPTGTQTP 3552



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 53/262 (20%), Positives = 95/262 (36%), Gaps = 35/262 (13%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P     P        
Sbjct: 3524 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3583

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-Q 319
              + P    T     +   I+    V T   T    Q+         P+   IT+  +  
Sbjct: 3584 TTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVT 3633

Query: 320  AAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
                 T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q  
Sbjct: 3634 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTP 3690

Query: 377  VSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
             +TP+     V    + + TQ P T        P++      +++  +P+P P  T   +
Sbjct: 3691 TTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPT 3737

Query: 433  NASNATVVPQNSSARSTCSLTP 454
                 T      +   T + TP
Sbjct: 3738 TTPITTTTTVTPTPTPTGTQTP 3759



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 53/262 (20%), Positives = 95/262 (36%), Gaps = 35/262 (13%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P     P        
Sbjct: 3731 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3790

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-Q 319
              + P    T     +   I+    V T   T    Q+         P+   IT+  +  
Sbjct: 3791 TTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVT 3840

Query: 320  AAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
                 T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q  
Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTP 3897

Query: 377  VSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
             +TP+     V    + + TQ P T        P++      +++  +P+P P  T   +
Sbjct: 3898 TTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPT 3944

Query: 433  NASNATVVPQNSSARSTCSLTP 454
                 T      +   T + TP
Sbjct: 3945 TTPITTTTTVTPTPTPTGTQTP 3966



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 53/262 (20%), Positives = 95/262 (36%), Gaps = 35/262 (13%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P     P        
Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3997

Query: 261  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-Q 319
              + P    T     +   I+    V T   T    Q+         P+   IT+  +  
Sbjct: 3998 TTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVT 4047

Query: 320  AAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
                 T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q  
Sbjct: 4048 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTP 4104

Query: 377  VSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
             +TP+     V    + + TQ P T        P++      +++  +P+P P  T   +
Sbjct: 4105 TTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPT 4151

Query: 433  NASNATVVPQNSSARSTCSLTP 454
                 T      +   T + TP
Sbjct: 4152 TTPITTTTTVTPTPTPTGTQTP 4173



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 12/137 (8%)

Query: 323  LSTQAQPSNQ-SPMSLTSDASSPRSYVSP---RISTPQTNTVPIKPLISTPPVSSQPKVS 378
            ++T + P+   SP   ++    P +  SP     +TP   T P  P+ +T   ++ P  +
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTT---TTPPPTT 1452

Query: 379  TPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNAT 438
            TP     P+S + T  P T        P  P +     +  + +P P  T+  S  +   
Sbjct: 1453 TP---SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPP--TTTPSPPTTTP 1507

Query: 439  VVPQNSSARSTCSLTPA 455
            + P  S+     + TP+
Sbjct: 1508 ITPPASTTTLPPTTTPS 1524



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 57/286 (19%), Positives = 97/286 (33%), Gaps = 37/286 (12%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 3973 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4032

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 4033 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 4082

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 4083 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 4140

Query: 366  ISTPPVSSQPKVSTPVVKQGPV--------SQSATQQPVTADKQQGHEPVSPRSLQRSSS 417
             +  P  +Q   +TP+     V        +Q+ T  P+T        P    +     +
Sbjct: 4141 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPT 4199

Query: 418  QRSPSP-------GPNHTSNSSNASNATVVPQNSSARSTCSLTPAL 456
              S +P        P   S++   S +T  P   S     +L PA+
Sbjct: 4200 HTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAI 4245



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 50/251 (19%), Positives = 91/251 (36%), Gaps = 34/251 (13%)

Query: 212  VSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATL 271
            V+   T  +T++ +   PT+ P T+ + V  +P P     P          + P    T 
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1938

Query: 272  QLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-QAAQLSTQAQPS 330
                +   I+    V T   T    Q+         P+   IT+  +       T  Q  
Sbjct: 1939 TQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVTPTPTPTGTQTP 1988

Query: 331  NQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPV 387
              +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q   +TP+     V
Sbjct: 1989 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTV 2045

Query: 388  ----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQN 443
                + + TQ P T        P++      +++  +P+P P  T   +     T     
Sbjct: 2046 TPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPTTTPITTTTTVT 2092

Query: 444  SSARSTCSLTP 454
             +   T + TP
Sbjct: 2093 PTPTPTGTQTP 2103



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 37/169 (21%), Positives = 65/169 (38%), Gaps = 7/169 (4%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLR 261
            +G  T    P++ + T   T + +G    + PPT  S  P++ +  S  PP    P   R
Sbjct: 4168 TGTQTPTTTPITTTTTVTPTPTPTGTQ--TGPPTHTSTAPIAELTTSNPPPESSTPQTSR 4225

Query: 262  QL-LPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQA 320
                P  ++T  L+     I   +    +  T  +  S  H   T  P     TS     
Sbjct: 4226 STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGH---TLSPPPSTTTSPPGTP 4282

Query: 321  AQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQ-TNTVPIKPLIST 368
             + +T    S  +P ++ +  +S  +     +STP    T  ++P  S+
Sbjct: 4283 TRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSS 4331



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 39/273 (14%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 1903 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1962

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 1963 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 2012

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 2013 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 2070

Query: 366  ISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             +  P  +Q   +TP+     V    + + TQ P T        P++      +++  +P
Sbjct: 2071 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTP 2116

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +P P  T   +     T      +   T + TP
Sbjct: 2117 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2149



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 39/273 (14%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2169

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 2219

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 2220 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 2277

Query: 366  ISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             +  P  +Q   +TP+     V    + + TQ P T        P++      +++  +P
Sbjct: 2278 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTP 2323

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +P P  T   +     T      +   T + TP
Sbjct: 2324 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2356



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 39/273 (14%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2376

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 2377 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 2426

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 2427 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 2484

Query: 366  ISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             +  P  +Q   +TP+     V    + + TQ P T        P++      +++  +P
Sbjct: 2485 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTP 2530

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +P P  T   +     T      +   T + TP
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2563



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 39/273 (14%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 2584 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 2633

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 2634 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 2691

Query: 366  ISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             +  P  +Q   +TP+     V    + + TQ P T        P++      +++  +P
Sbjct: 2692 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTP 2737

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +P P  T   +     T      +   T + TP
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2770



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 39/273 (14%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2790

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 2840

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 2841 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 2898

Query: 366  ISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             +  P  +Q   +TP+     V    + + TQ P T        P++      +++  +P
Sbjct: 2899 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTP 2944

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +P P  T   +     T      +   T + TP
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2977



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 39/273 (14%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2997

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 2998 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 3047

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 3048 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 3105

Query: 366  ISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             +  P  +Q   +TP+     V    + + TQ P T        P++      +++  +P
Sbjct: 3106 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTP 3151

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +P P  T   +     T      +   T + TP
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3184



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 39/273 (14%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3204

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 3205 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 3254

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 3255 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 3312

Query: 366  ISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             +  P  +Q   +TP+     V    + + TQ P T        P++      +++  +P
Sbjct: 3313 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTP 3358

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +P P  T   +     T      +   T + TP
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3391



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 39/273 (14%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3411

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 3412 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 3461

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 3462 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 3519

Query: 366  ISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             +  P  +Q   +TP+     V    + + TQ P T        P++      +++  +P
Sbjct: 3520 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTP 3565

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +P P  T   +     T      +   T + TP
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3598



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 39/273 (14%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3618

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 3619 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 3668

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 3669 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 3726

Query: 366  ISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             +  P  +Q   +TP+     V    + + TQ P T        P++      +++  +P
Sbjct: 3727 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTP 3772

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +P P  T   +     T      +   T + TP
Sbjct: 3773 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3805



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 39/273 (14%)

Query: 195  TATSGFASGKSTSGDKPVSHSCT-----TPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            T T+   +   T    P +   T     TP+ +      PT+ P T+ + V  +P P   
Sbjct: 3766 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3825

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
              P          + P    T     +   I+    V T   T    Q+         P+
Sbjct: 3826 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PT 3875

Query: 310  AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPL 365
               IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P 
Sbjct: 3876 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP- 3933

Query: 366  ISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             +  P  +Q   +TP+     V    + + TQ P T        P++      +++  +P
Sbjct: 3934 -TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTP 3979

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
            +P P  T   +     T      +   T + TP
Sbjct: 3980 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4012



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 46/182 (25%), Positives = 70/182 (38%), Gaps = 19/182 (10%)

Query: 202  SGKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPI--PPLLQDPN 258
            +G  T    P++ + T   T + +G   PT+ P T+ + V  +P P      PP      
Sbjct: 4145 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTA 4204

Query: 259  LLRQLL----PALQATLQLNNSNVDISKINEVLTAAVTQAS-LQSIIHKFLTAGPSAFNI 313
             + +L     P   +T Q + S       +  LT + T  S L   I    TA PS    
Sbjct: 4205 PIAELTTSNPPPESSTPQTSRST------SSPLTESTTLLSTLPPAIEMTSTAPPSTPTA 4258

Query: 314  TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNT----VPIKPLISTP 369
             +  S    LS     +  SP    +  ++  S  +P  ST QT T     P    +STP
Sbjct: 4259 PTTTSGGHTLSPPPS-TTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTP 4317

Query: 370  PV 371
             +
Sbjct: 4318 SI 4319


>gi|151301228 formin binding protein 3 [Homo sapiens]
          Length = 930

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 18/131 (13%)

Query: 135 WSEHISSSGKKYYYNCRTEVSQWEKPKEW--LEREQRQKEANKMAVNS-----FPKDRDY 187
           W E+ S SGK YYYN +T+ S+W KPKE   LE  Q    A  +   S        +   
Sbjct: 160 WKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESS 219

Query: 188 RREVMQATATSGFAS----------GKSTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTS 236
           ++E    T+T+   +            + +    V+ +    + ++A+  N  TSA  T 
Sbjct: 220 KQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTV 279

Query: 237 ASAVPVSPVPQ 247
           +  VPV P P+
Sbjct: 280 SGTVPVVPEPE 290



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 53/227 (23%), Positives = 82/227 (36%), Gaps = 48/227 (21%)

Query: 135 WSEHISSSGKKYYYNCRTEVSQWEKPKE-------------WLEREQRQKEANKMAVNSF 181
           W+EH S  G+ YYYN  T+ S WEKP +             W  +E +         NS 
Sbjct: 119 WTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPW--KEYKSDSGKPYYYNSQ 176

Query: 182 PKDRDYRR-------EVMQATATSGFASGKST------SGDKPVSHSCTTPSTSSASGLN 228
            K+  + +       E  Q T  +G    KS       + +      CTT ST+      
Sbjct: 177 TKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPV---- 232

Query: 229 PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEV-- 286
           PT+  PT+ S +  +    + +               A  A     N+N   S  N V  
Sbjct: 233 PTTEIPTTMSTMAAAEAAAAVV-----------AAAAAAAAAAAAANANASTSASNTVSG 281

Query: 287 LTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQS 333
               V +  + SI+    T   +   +T    + AQL++     +QS
Sbjct: 282 TVPVVPEPEVTSIV---ATVVDNENTVTISTEEQAQLTSTPAIQDQS 325



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 31/145 (21%), Positives = 58/145 (40%), Gaps = 13/145 (8%)

Query: 66  ENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTS 125
           ++ +S +  HSK    H HR R R    S S  ++SH+      S S S++  ++ ++  
Sbjct: 778 QHHHSKNKKHSKKSKKH-HRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAE-- 834

Query: 126 DAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDR 185
                     SE      KK+    +    + + P+   ERE+ +KE ++ +     + R
Sbjct: 835 ----------SERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQR 884

Query: 186 DYRREVMQATATSGFASGKSTSGDK 210
              +       T   +    TSG +
Sbjct: 885 SESKHKSPKKKTGKDSGNWDTSGSE 909


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 76/303 (25%), Positives = 113/303 (37%), Gaps = 25/303 (8%)

Query: 194  ATATSGFASGKSTSGDKPVSHSCTTP----STSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            ++A++G  S    +G    S    TP     TSS S  + T  P TS S+V       +P
Sbjct: 3367 SSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDT--TP 3424

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL----- 304
            +P          Q  P    +L    S+V       +L   VT AS  S  H        
Sbjct: 3425 LPVTDASSASTGQATPLPVTSL----SSVSTGDTTPLL---VTDASSVSTGHATPLPVTD 3477

Query: 305  TAGPSAFNITSL-ISQAAQLST-QAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPI 362
            T+  S  + T L ++  +  ST QA P   + +S  S   +    V+   S    +  P+
Sbjct: 3478 TSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPL 3537

Query: 363  KPLISTPPVSSQPKVSTPVVKQGPVSQS-ATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
             P+  T   S+      PV      S   AT  PVT          +P  +  +SS  + 
Sbjct: 3538 -PVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTG 3596

Query: 422  SPGPNHTSNSSNASNATVVP---QNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEK 478
               P H ++ S+AS   V P    ++S+ ST   TP L    S     H    P   A  
Sbjct: 3597 HVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASS 3656

Query: 479  QAS 481
             ++
Sbjct: 3657 AST 3659



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 68/283 (24%), Positives = 123/283 (43%), Gaps = 31/283 (10%)

Query: 192  MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQ---- 247
            +  T  S  ++G +T     +  S +T  T      +P+SA    A+ +PV+ +      
Sbjct: 3697 LPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTG 3756

Query: 248  --SPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISK--INEVLTAAVTQASLQSIIHKF 303
              +P+P         R   P L  T   + S  D ++  + +V +A+   A+   +    
Sbjct: 3757 DTTPLPVTDTSSASTRHATP-LPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTS-- 3813

Query: 304  LTAGPSAFNITSL-ISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPI 362
             T+  S  + T L ++  + +ST     + + + +TS +S+   + +P    P T+T  +
Sbjct: 3814 -TSSASTGDTTPLPVTDTSSVST----GHATSLPVTSRSSASTGHATP---LPVTDTSSV 3865

Query: 363  KPLISTP-PVSSQPKVS----TPVVKQGPVSQS---ATQQPVTADKQQGHEPVSPRSLQR 414
                +TP PV+S   VS    TP+    P S S   AT  PVT+         +P  +  
Sbjct: 3866 STGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTN 3925

Query: 415  SSSQRSPSPGPNHTSNSSNAS---NATVVPQNSSARSTCSLTP 454
            +SS  +    P H ++ S+AS    +T+   ++S+ ST   TP
Sbjct: 3926 ASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATP 3968



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 71/289 (24%), Positives = 116/289 (40%), Gaps = 27/289 (9%)

Query: 192  MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 251
            +  T TS  ++G +T      + S +T  T+     +P+SA     + +PV+  P +   
Sbjct: 2465 LPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTG 2524

Query: 252  PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF-----LTA 306
                 P      L    AT  L+ ++   +      +  VT  S  S  H        T+
Sbjct: 2525 DTTPLPVTNASSLSTRHAT-SLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTS 2583

Query: 307  GPSAFNITSL-ISQAAQLST-QAQP-------------SNQSPMSLTSDASSPRSYVSPR 351
              S  + T L ++     ST QA P             +   P++ TS AS+  +   P 
Sbjct: 2584 SASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPV 2643

Query: 352  ISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQS---ATQQPVT--ADKQQGHEP 406
             +T   +T    PL  T P S+    +TP+      S S   AT  PVT  +    GH  
Sbjct: 2644 TNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHAT 2703

Query: 407  VSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP-QNSSARSTCSLTP 454
              P ++  S+S    +P P   ++S +  +AT +P  ++S+ ST   TP
Sbjct: 2704 SLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATP 2752



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 71/276 (25%), Positives = 107/276 (38%), Gaps = 25/276 (9%)

Query: 194  ATATSGFASGKSTSGDKPVSHSCTTP----STSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            ++A++G A+    +    VS   TTP      SSAS    T  P TS S+V       +P
Sbjct: 1127 SSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDT--TP 1184

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIH--KFLTAG 307
            +P             P L        ++   +         VT AS  S  H        
Sbjct: 1185 LPVTSPSSASTGHATPLLV-------TDTSSASTGHATPLPVTDASSVSTDHATSLPVTI 1237

Query: 308  PSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVS---PRISTPQTNTVPIKP 364
            PSA + T   +      T +  + Q+   L +D SS  +  +   P  ST   +T  + P
Sbjct: 1238 PSAAS-TGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTP 1296

Query: 365  LISTPPVSSQPKVSTPVVKQGPVSQSATQQ---PVTADKQQGHEPVSPRSLQRSSSQRSP 421
            L  T P S+    +TP+      S S       PVT+         +P  +  +SS  + 
Sbjct: 1297 LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTG 1356

Query: 422  SPGPNHTSNSSNAS--NATVVPQNS-SARSTCSLTP 454
               P H +++S+AS   AT +P  S S+ ST   TP
Sbjct: 1357 HTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTP 1392



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 69/269 (25%), Positives = 109/269 (40%), Gaps = 19/269 (7%)

Query: 192  MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 251
            +  T TS  ++G +T      + S +T   +     +P+SA    A+ VPV+    +   
Sbjct: 3857 LPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTG 3916

Query: 252  PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAF 311
                 P      L    AT  L+ ++   +   +  T  VT AS  S      T   +  
Sbjct: 3917 DTTPLPVTNASSLSTGHAT-PLHVTSPSSASRGDTSTLPVTDASSAS------TGHATPL 3969

Query: 312  NITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPP- 370
             +TSL S +   +T        P++ TS AS+ ++   P  S    +T    PL  T P 
Sbjct: 3970 PLTSLSSVSTGDTTPL------PVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPS 4023

Query: 371  -VSSQPKVSTPVVKQGPVSQS-ATQQPVTADKQQGHEPVSPRSLQRSSSQRS--PSPGPN 426
              SS    S PV     VS    T  PVT+         +P  +  +SS  +   +P P 
Sbjct: 4024 SASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPV 4083

Query: 427  HTSNSSNASNATVVPQNS-SARSTCSLTP 454
              ++S++  +AT +P  S S+ ST   TP
Sbjct: 4084 TDTSSASTGHATPLPVTSLSSVSTGHATP 4112



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 77/308 (25%), Positives = 124/308 (40%), Gaps = 58/308 (18%)

Query: 193  QATATSGFA--SGKSTSGDKPVSHSCTTPSTSSASGLNPTSAP--PTSASAVPVSPVPQS 248
            ++T  SG    S  ++SG +  S    TPS+S ASG  P+ +    TS      S  P  
Sbjct: 777  ESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPS- 835

Query: 249  PIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAG- 307
                  +D +  +     L A     +++     ++  + +++   +    + +  TAG 
Sbjct: 836  ------RDSHTTQSTTELLSA-----SASHGAIPVSTGMASSIVPGTFHPTLSEASTAGR 884

Query: 308  ---------PSAF-NITSLISQAAQLSTQAQPSNQSPMSLTSDAS--------SPRSYVS 349
                     PSA    T+ IS+ AQ            +SL S A+        +P S  S
Sbjct: 885  PTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITS 944

Query: 350  PRISTPQTNTVPIKP----------LIS--TP-PVSSQPKVST------PVVKQGPVSQS 390
              +++PQT T  + P          LIS  TP PV+     ST       V     VS  
Sbjct: 945  TGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTG 1004

Query: 391  -ATQQPVTADK--QQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP-QNSSA 446
             AT  PVT+      GH    P +   S S    +P P  + +S++  ++T +P  ++S+
Sbjct: 1005 HATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSS 1064

Query: 447  RSTCSLTP 454
             ST  +TP
Sbjct: 1065 ASTGHVTP 1072



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 74/305 (24%), Positives = 109/305 (35%), Gaps = 47/305 (15%)

Query: 194  ATATSGFASGKSTSGDKPVSHSCTTP----STSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            ++A++G A+    +     S   TTP     TSS S  + T  P T  S+       + P
Sbjct: 3191 SSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLP 3250

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
            +  +          LP        N S+V      + +   VT  S  S  H       +
Sbjct: 3251 VTDISSASTGQATPLPVT------NTSSVSTG---DTMPLPVTSPSSASTGHA------T 3295

Query: 310  AFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP 369
               +TS  S +   +T        P++ TS AS+  +   P   T   +T    PL  T 
Sbjct: 3296 PLPVTSTSSASTGHATPV------PVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTS 3349

Query: 370  PVSSQPKVSTPVVKQGPVSQS-------------------ATQQPV--TADKQQGHEPVS 408
            P S+    +TP+    P S S                   AT  PV  T+    GH    
Sbjct: 3350 PSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPL 3409

Query: 409  PRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNS-SARSTCSLTPALAAHFSENLIKH 467
            P +   S S    +P P   ++S++   AT +P  S S+ ST   TP L    S     H
Sbjct: 3410 PVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGH 3469

Query: 468  VQGWP 472
                P
Sbjct: 3470 ATPLP 3474



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 82/317 (25%), Positives = 123/317 (38%), Gaps = 51/317 (16%)

Query: 194  ATATSGFASGKSTSGDKPVSHSCTT------PSTSSASGLNPTSAPPTSAS--AVPVSPV 245
            AT +S  ASG + SG + +S S  T      PS  S +  + T     SAS  A+PVS  
Sbjct: 803  ATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTG 862

Query: 246  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQA----------- 294
              S I P    P L  +   A + T Q + ++   S       + + Q            
Sbjct: 863  MASSIVPGTFHPTL-SEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDT 921

Query: 295  -SLQS-IIHKFLTAGPSAFNITSLISQAAQLSTQ-------------AQPSNQSPMSLTS 339
             SL S     F T  P+  +ITS    + Q  T              A  SN +P+ +T 
Sbjct: 922  ISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTY 981

Query: 340  DASSPRSYVSPRISTPQTNTVPIKPLISTP-PVSSQPKVSTPVVKQGPVSQSATQQPVTA 398
             +S+   + +P   T  ++   +    +TP PV+S   VST      PV+        T+
Sbjct: 982  ASSASTGHTTPLHVTDASS---VSTGHATPLPVTSPSSVSTGHTTPLPVTD-------TS 1031

Query: 399  DKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP---QNSSARSTCSLTPA 455
             +  GH  V+P  +   SS  +    P   +++S+AS   V P    + S+ ST   TP 
Sbjct: 1032 SESTGH--VTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPL 1089

Query: 456  LAAHFSENLIKHVQGWP 472
                 S     H    P
Sbjct: 1090 PVTDTSSASTGHATSLP 1106



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 67/269 (24%), Positives = 106/269 (39%), Gaps = 35/269 (13%)

Query: 192  MQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 251
            +  T TS  ++G +TS   PV+       TSSAS  + TS P T  S+        +P+P
Sbjct: 2145 LPVTDTSSVSTGHATS--LPVT------DTSSASTGHATSLPVTDTSSASTGHA--TPLP 2194

Query: 252  PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAF 311
                      Q  P       L  ++   +     +   VT  S  S      T   +  
Sbjct: 2195 VTDTSSASTGQATP-------LPVTSPSSASTGHAIPLLVTDTSSAS------TGQATPL 2241

Query: 312  NITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPV 371
             +TSL S +   +T    ++ S +S     S P + +S  +ST  T  +P+     T P 
Sbjct: 2242 PVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSS-VSTGDTTPLPV-----TSPS 2295

Query: 372  SSQPKVSTPVVKQGPVSQS---ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHT 428
            S+    +TP+      S S   AT  PVT+         +P  +   SS  +    P H 
Sbjct: 2296 SASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHV 2355

Query: 429  SNSSNASNATVVP---QNSSARSTCSLTP 454
            +++S+ S     P    +SS+ S+   TP
Sbjct: 2356 TDASSVSTGDTTPLPVTSSSSASSGHTTP 2384



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 72/302 (23%), Positives = 120/302 (39%), Gaps = 45/302 (14%)

Query: 194  ATATSGFASGKSTSGDKPVSHSCTTP----STSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            ++A++G A+    +     S   TTP     TSS S  + TS P TS S+         P
Sbjct: 3799 SSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLP 3858

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
            +             LP + +T  ++  +     +    +A+   A+   +     T+  S
Sbjct: 3859 VTDTSSVSTGHATPLP-VTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTS---TSSAS 3914

Query: 310  AFNITSL-ISQAAQLST------------QAQPSNQSPMSLTSDASSPRSYVSP------ 350
              + T L ++ A+ LST             A   + S + +T  +S+   + +P      
Sbjct: 3915 TGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSL 3974

Query: 351  -RISTPQTNTVPIKPLIS------TP-PVSSQPKVSTPVVKQGPV-------SQSATQQP 395
              +ST  T  +P+    S      TP PV+S   VST      PV       S   T  P
Sbjct: 3975 SSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLP 4034

Query: 396  VT--ADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP-QNSSARSTCSL 452
            VT  +    GH    P +   S+S    +P P   ++S++  +AT +P  ++S+ ST   
Sbjct: 4035 VTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHA 4094

Query: 453  TP 454
            TP
Sbjct: 4095 TP 4096



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 74/305 (24%), Positives = 115/305 (37%), Gaps = 43/305 (14%)

Query: 192  MQATATSGFASGKST----SGDKPVSHSCTTP----STSSASGLNPTSAPPTSASAVPVS 243
            +  T+ S  ++G +T    +     S    TP     TSSAS  + T  P T AS+V   
Sbjct: 1377 LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTD 1436

Query: 244  PVPQSPIPPLLQDPNLLRQLLPAL--------QAT--LQLNNSNVDISKINEVLTAAVTQ 293
                 P+             LP          QAT  L  + S+V       +   + + 
Sbjct: 1437 HATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSS 1496

Query: 294  ASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSP--- 350
            AS   +    +T+  SA    +       LS+ A   +  P+ +TS +S+     +P   
Sbjct: 1497 ASTGHVTPLHVTSPSSASTGHATPLPVTSLSS-ASTGDTMPLPVTSPSSASTGDTTPLPV 1555

Query: 351  ----RISTPQTNTVPIK-----------PLISTPPVSSQPKVSTPVVKQGPVSQSA---T 392
                 +ST  T  +P+            PL  T   S+    +TP+    P S S    T
Sbjct: 1556 TDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTT 1615

Query: 393  QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNAS--NATVVPQNS-SARST 449
              PVT          +P  +  +SS  +    P H ++ S+AS  +AT +P  S S+ ST
Sbjct: 1616 PLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSAST 1675

Query: 450  CSLTP 454
               TP
Sbjct: 1676 GHATP 1680



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 66/271 (24%), Positives = 111/271 (40%), Gaps = 29/271 (10%)

Query: 195  TATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLL 254
            T  S  ++G++T        S +T  T+     +P+SA    A+++PV+    +      
Sbjct: 3076 TDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTT 3135

Query: 255  QDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNIT 314
              P +          T  L  ++   S   +     VT+ S  S  H    A P      
Sbjct: 3136 SLP-VTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGH----ATP------ 3184

Query: 315  SLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP-PVSS 373
             L++ A+  ST     + +P+ +TS +S+     +P    P T+T  +    +TP PV+ 
Sbjct: 3185 LLVTDASSAST----GHATPLHVTSPSSASTGDTTP---VPVTDTSSVSTGHATPLPVTG 3237

Query: 374  QPKVSTPVVKQGPVSQ-------SATQQPV--TADKQQGHEPVSPRSLQRSSSQRSPSPG 424
                ST    + PV+         AT  PV  T+    G     P +   S+S    +P 
Sbjct: 3238 LSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPL 3297

Query: 425  PNHTSNSSNASNATVVPQNS-SARSTCSLTP 454
            P  +++S++  +AT VP  S S+ ST   TP
Sbjct: 3298 PVTSTSSASTGHATPVPVTSTSSASTGHTTP 3328



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 74/297 (24%), Positives = 118/297 (39%), Gaps = 45/297 (15%)

Query: 192  MQATATSGFASGKSTSGDKPVSHSCTTPST--------SSASGLNPTSAPPTSASAVPVS 243
            +  T+ S  ++G +T      + S +T  T        SSAS  + TS P T AS+V   
Sbjct: 1809 LPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTG 1868

Query: 244  PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF 303
                     L+ D + +     +   T  L  ++ + +   +     VT AS  S     
Sbjct: 1869 HATSL----LVTDASSV-----STGDTTPLPVTDTNSASTGDTTPLHVTDASSVS----- 1914

Query: 304  LTAGPSAFNITSLISQAAQLST--------QAQPSNQSPMSLTSDASSPRSYVSPRISTP 355
             T   ++  +TSL S +   +T         A   + +P+ +T  +S P  + +   S P
Sbjct: 1915 -TGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHAT---SLP 1970

Query: 356  QTNTVPIKPLISTP-PVSSQPKVST------PVVKQGPVSQ-SATQQPVT--ADKQQGHE 405
             T+   +    +TP PV+    VST      PV     VS   AT  PVT  +    G  
Sbjct: 1971 VTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDT 2030

Query: 406  PVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNS-SARSTCSLTPALAAHFS 461
               P +   S+S    +P P  + +S +  + T +P  S S+ ST   TP L    S
Sbjct: 2031 TPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDAS 2087



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 64/284 (22%), Positives = 109/284 (38%), Gaps = 35/284 (12%)

Query: 195 TATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLL 254
           TATS   S  +TS       + TT + S+      TS+ P + S +PV+        P  
Sbjct: 245 TATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEG 304

Query: 255 QDPNLLRQLLPALQATLQLNN--SNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 312
           Q P    +           N+   +V+ ++++++ T      +L  +    + + PS FN
Sbjct: 305 QSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTL----NTLTPVTTSTVLSSPSGFN 360

Query: 313 ITSLISQAAQLSTQAQPSNQSPMSLTSDASS-----PRS-------------YVSPRIS- 353
            +  +SQ    S +   S+ S +S T   +S     P S              VS  IS 
Sbjct: 361 PSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISA 420

Query: 354 -TPQTNTVPIKPLIST--PPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPR 410
            T + +T+     +ST   P S  PK+ST    Q       T +P            SP 
Sbjct: 421 ITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRP------HERSSFSPG 474

Query: 411 SLQRSSSQRSPSPGPNHTSNSSNAS-NATVVPQNSSARSTCSLT 453
             Q   +    +  P+  S+  + + + T +P  S+  +T  +T
Sbjct: 475 VSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVT 518



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 71/289 (24%), Positives = 107/289 (37%), Gaps = 31/289 (10%)

Query: 194  ATATSGFASGKSTSGDKPVSHSCTTP----STSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            ++ ++G A+    +     S   TTP    S SSAS  + T  P T AS+VP       P
Sbjct: 1911 SSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLP 1970

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
            +             LP   A      S+V       +    VT  S  S      T   +
Sbjct: 1971 VTDASSVSTGHATPLPVTDA------SSVSTGHATPL---PVTDTSSVS------TGQAT 2015

Query: 310  AFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP 369
               +TSL S +   +T        P++ TS AS+ +    P  S    +T    PL  T 
Sbjct: 2016 PLPVTSLSSASTGDTTPL------PVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTS 2069

Query: 370  PVSSQPKVSTPVVKQGPVSQS---ATQQPVT--ADKQQGHEPVSPRSLQRSSSQRSPSPG 424
            P S+    +TP++     S S   AT   VT  +    GH      +   S S    +P 
Sbjct: 2070 PSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPL 2129

Query: 425  PNHTSNSSNASNATVVP-QNSSARSTCSLTPALAAHFSENLIKHVQGWP 472
            P  + +S++  + T +P  ++S+ ST   T       S     H    P
Sbjct: 2130 PVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLP 2178



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 59/267 (22%), Positives = 103/267 (38%), Gaps = 32/267 (11%)

Query: 194  ATATSGFASGKSTSGDKPVSHSCTTP----STSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            ++A++G  +    +    VS   TTP    S SSAS  + T  P T  S+   S    +P
Sbjct: 1543 SSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSA--SKGDTTP 1600

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
            +P  +  P+       +   T  L  ++   +   +     VT AS  S  H       +
Sbjct: 1601 LP--VTSPSSA-----STGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHA------T 1647

Query: 310  AFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPR----ISTPQTNTVPIKPL 365
              ++TS         + A   + +P+ +TS +S+   + +P     +S+  T+     P+
Sbjct: 1648 PLHVTS--------PSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPV 1699

Query: 366  ISTPPVSSQPKVSTPVVKQGPVSQS-ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG 424
                  S+      PV     VS    T  PVT+         SP  +  +SS  +    
Sbjct: 1700 TDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQAT 1759

Query: 425  PNHTSNSSNASNATVVPQNSSARSTCS 451
            P   +++S+ S A   P   +  S+ S
Sbjct: 1760 PLPVTDTSSVSTAHATPLPVTGLSSAS 1786



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 66/266 (24%), Positives = 108/266 (40%), Gaps = 20/266 (7%)

Query: 191  VMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPI 250
            ++  T TS  + G +TS   PV+ + ++ ST  A+ L+ TS  P+SAS    +P+P +  
Sbjct: 2864 LLPVTDTSSASIGHATS--LPVTDT-SSISTGHATPLHVTS--PSSASTGHATPLPVTDT 2918

Query: 251  PPL-LQDPNLLRQLLPALQATLQLNNSNV-DISKINEVLTAAVTQASLQSIIHKFLTAGP 308
                    N L    P+  +T       V D S  +      +   SL S+     T   
Sbjct: 2919 SSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSV----STGDT 2974

Query: 309  SAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLIST 368
            +   +TS  S +   +T        P++ TS AS+ ++   P  ST   +T    PL  T
Sbjct: 2975 TPLPVTSPSSASTGHTTPL------PVTDTSSASTGQATALPVTSTSSASTGDTTPLPVT 3028

Query: 369  PPVSSQPKVST--PVVKQGPVSQ-SATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGP 425
               S+    +T  PV     VS    T  PVT+         +P  +  +SS  +    P
Sbjct: 3029 DTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATP 3088

Query: 426  NHTSNSSNASNATVVPQNSSARSTCS 451
               ++ S+ S     P   ++ S+ S
Sbjct: 3089 LPVTSLSSVSTGDTTPLPVTSPSSAS 3114



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 63/278 (22%), Positives = 107/278 (38%), Gaps = 29/278 (10%)

Query: 194  ATATSGFASGKSTSGDKPVS--HSCTTPST--SSASGLNPTSAPPTSASAVPVSPVPQSP 249
            ++A+SG  +    +    VS  H+ + P T  SS S  + T  P T AS+V        P
Sbjct: 2711 SSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLP 2770

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNN--SNVDISKINEVLTAAVTQASLQSIIHKFLTAG 307
            +  L          LP    +       + + ++ ++ V T   T   +        T  
Sbjct: 2771 LTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDT-SSASTGH 2829

Query: 308  PSAFNITSLISQAAQLSTQAQPSNQS----------PMSLTSDASSPRSYVSPRISTPQT 357
             ++  +T   S +   +T    ++ S          P++ TS AS   +   P   T   
Sbjct: 2830 ATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSI 2889

Query: 358  NTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 417
            +T    PL  T P S+    +TP+    PV+        T+    GH      +   S+S
Sbjct: 2890 STGHATPLHVTSPSSASTGHATPL----PVTD-------TSSASTGHANPLHVTSPSSAS 2938

Query: 418  QRSPSPGPNHTSNSSNASNATVVPQNS-SARSTCSLTP 454
                +P P   ++S++  +AT +P  S S+ ST   TP
Sbjct: 2939 TGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTP 2976



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 68/294 (23%), Positives = 105/294 (35%), Gaps = 63/294 (21%)

Query: 194  ATATSGFASGKSTSGDKPVSHSCTTP----STSSASGLNPTSAPPTSASAVPVSPVPQSP 249
            ++A++G A+    +     S    TP     TSSAS  + T  P TS S+V        P
Sbjct: 2919 SSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLP 2978

Query: 250  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
            +              P+  +T                    VT  S  S      T   +
Sbjct: 2979 VTS------------PSSAST-------------GHTTPLPVTDTSSAS------TGQAT 3007

Query: 310  AFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP 369
            A  +TS  S +   +T        P++ TS AS+ ++   P  S    +T    PL  T 
Sbjct: 3008 ALPVTSTSSASTGDTTPL------PVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTS 3061

Query: 370  PVSSQPKVSTPVVKQGPVSQS---ATQQPVT------------------ADKQQGHEPVS 408
            P S+    +TP++     S S   AT  PVT                  +    GH    
Sbjct: 3062 PSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSL 3121

Query: 409  PRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP-QNSSARSTCSLTPALAAHFS 461
            P +   S+S    +  P   ++S+   + T +P  ++S+ ST   TP L    S
Sbjct: 3122 PVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETS 3175



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 37/181 (20%), Positives = 76/181 (41%), Gaps = 15/181 (8%)

Query: 288 TAAVTQASLQSIIHKFLTA---GPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSP 344
           T    ++   ++ H+  +     PS  N+T  +SQ    S +   S+   ++ TS  +S 
Sbjct: 203 TQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSE 262

Query: 345 RSYVSPRISTP-----QTNTVPIKPLISTPPVSSQPKVSTPVVKQGPV--SQSATQQPVT 397
           +  V+    +      +T++VP+    S  PV+S   V+     Q P   S+++TQ    
Sbjct: 263 KITVTTSTGSTLGNPGETSSVPVTG--SLMPVTSAALVTFDPEGQSPATFSRTSTQDTTA 320

Query: 398 ADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNAS---NATVVPQNSSARSTCSLTP 454
             K    + V    + + ++  + +P    T  SS +    + TV  +   +  T + +P
Sbjct: 321 FSKNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSP 380

Query: 455 A 455
           +
Sbjct: 381 S 381



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 16/56 (28%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 196  ATSGFASGKSTSGDKPV---SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQS 248
            A S   S  + S D P+   +   TTPS  +  G    ++PP + S   +S +P +
Sbjct: 4114 AVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPST 4169


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 67/296 (22%), Positives = 123/296 (41%), Gaps = 45/296 (15%)

Query: 196  ATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS------------AVPVS 243
            +T+  +S ++T+G   VS + TTP+ +S+    P+S+P T+ +            A   +
Sbjct: 4468 STATASSTQATAGTPHVSTTATTPTVTSSKA-TPSSSPGTATALPALRSTATTPTATSFT 4526

Query: 244  PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQ---------- 293
             +P S +        L +   P    +    +S  +    + VLTA  T           
Sbjct: 4527 AIPSSSLGTTWT--RLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATP 4584

Query: 294  ASLQSIIHKF---------LTAGPSAFNITSLISQAAQLSTQAQPSNQSPM---SLTSDA 341
            +S     H            TA PS+   T+L +    +ST   P+  +P    S  + +
Sbjct: 4585 SSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL-TPPVWISTTTTPTTTTPTTSGSTVTPS 4643

Query: 342  SSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQ 401
            S P +  + R+ T  T TV    + +TP  S+Q   + P +     + +AT         
Sbjct: 4644 SIPGTTHTARVLTTTTTTVATGSM-ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSST 4702

Query: 402  QGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP--QNSSARSTC-SLTP 454
             G  P++P     +S+  +P+   +  ++SS+   AT +P   +++ +ST  S TP
Sbjct: 4703 PGTTPITP---VLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTP 4755



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 68/294 (23%), Positives = 109/294 (37%), Gaps = 39/294 (13%)

Query: 195  TATSGFASGKSTSGDKPVSHSCTTPST-----------SSASGLNPTSAPPTSASAVPVS 243
            TAT   A+  ST      S   TT +T           SS  G   T+  PT+ +    +
Sbjct: 3262 TATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTA 3321

Query: 244  PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF 303
                SP   L     +     P  + +    +S    +    VLT   T  +  S+    
Sbjct: 3322 TPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSM---- 3377

Query: 304  LTAGPSAFNITS-----LISQAAQLSTQAQPSNQS--------PMSLTSDASSPR---SY 347
              A PS+   TS     L + A  ++     +N S        P  LT+ A++P    S 
Sbjct: 3378 --ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSST 3435

Query: 348  VSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSA----TQQPVTADKQQG 403
            V+P  +   T+T P+    +T    S P  S   V+    S ++    T           
Sbjct: 3436 VTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTS 3495

Query: 404  HEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNS--SARSTCSLTPA 455
            H P +  S  + S+    SP P+  +  S  S  T  P ++  ++R+T + TP+
Sbjct: 3496 HTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPS 3549



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 51/292 (17%)

Query: 191  VMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPI 250
            V+  TAT+  A+G           S  TPS++  +  + T  P T+ +   V+P   S  
Sbjct: 3839 VLTTTATTTRATG-----------SVATPSSTPGTA-HTTKVPTTTTTGFTVTP---SSS 3883

Query: 251  PPLLQDPN--LLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGP 308
            P   + P   +     P    +    +S    +    VLT   T  +  S+      A P
Sbjct: 3884 PGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSM------ATP 3937

Query: 309  SAFNITS-----LISQAAQLSTQAQPSNQS--------PMSLTSDASSPR---SYVSPRI 352
            S+   TS     LI+ A  ++     +N S        P  LT+ A++P    S V+P  
Sbjct: 3938 SSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSS 3997

Query: 353  STPQTNTVPIKPLISTPPVSSQPKVSTPVVK-------QGPVSQSATQQPVTADKQQGHE 405
            +   T+T P+    +T    S    S   V+        G +  +   +P T      H 
Sbjct: 3998 ALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS---HT 4054

Query: 406  PVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA--RSTCSLTPA 455
            P +     + S+    SP P+  +  S  S  T  P +++A  R+T + TP+
Sbjct: 4055 PAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPS 4106



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 65/287 (22%), Positives = 111/287 (38%), Gaps = 41/287 (14%)

Query: 191  VMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPI 250
            V+ ATAT+  A+G           S  TPS++  +  + T  P T+ +    +P   SP 
Sbjct: 2025 VLTATATTTGATG-----------SVATPSSTPGTA-HTTKVPTTTTTGFTATP-SSSPG 2071

Query: 251  PPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSA 310
              L     +     P  + +    +S    +    VLT   T  +  S+      A PS+
Sbjct: 2072 TALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSM------ATPSS 2125

Query: 311  FNITS-----LISQAAQLSTQAQPSNQS--------PMSLTSDASSPRSY---VSPRIST 354
               TS     L + A  ++     +N S        P  LT+ A++P +    V+P  + 
Sbjct: 2126 STQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSAL 2185

Query: 355  PQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSA----TQQPVTADKQQGHEPVSPR 410
              T+T P+   ++T    S P  S   V+    S ++    T           H   +  
Sbjct: 2186 GTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATT 2245

Query: 411  SLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA--RSTCSLTPA 455
               + S+    SP P+  +  S  S  T  P +++A  R+T + TP+
Sbjct: 2246 GTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPS 2292



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 62/280 (22%), Positives = 107/280 (38%), Gaps = 43/280 (15%)

Query: 196  ATSGFASGKSTSGDKPVSHSCTTPST----------SSASGLNPTSAP-----PTSASAV 240
            +T   A+  ST G  P     T+P+T          SS+S    T+ P      T ++A 
Sbjct: 4265 STGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTAT 4324

Query: 241  PVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSII 300
             V+P+P S +      P   +   P    +    +S  + +  + VLT   T     S  
Sbjct: 4325 SVTPIPSSTLGTTGTLPE--QTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATS-- 4380

Query: 301  HKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTV 360
                T+ PS+   T+ I    +L+T A  +  +  + T  ++   +++   ++T  T T 
Sbjct: 4381 ---STSTPSSTPGTTWI--LTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTA 4435

Query: 361  PIKPLISTPPVSSQP-------KVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQ 413
                  ST   SS P       + ST      P   +AT     A     H   +  +  
Sbjct: 4436 STG---STATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT 4492

Query: 414  RSSSQRSPSPGP---------NHTSNSSNASNATVVPQNS 444
             +SS+ +PS  P           T+ +  A++ T +P +S
Sbjct: 4493 VTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSS 4532



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 67/275 (24%), Positives = 96/275 (34%), Gaps = 45/275 (16%)

Query: 196  ATSGFASGKSTSGD-----KPVSHSCTTPSTSSASGLNPTSA-----PPTSASAVPVSPV 245
            ATS  A+  ST G      KP + + TT ST S +   PTS      PP   +    +P 
Sbjct: 1893 ATSSTATPSSTPGTTWILTKPTTTATTTASTGSTA--TPTSTLRTAPPPKVLTTTATTPT 1950

Query: 246  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 305
              S        P      LPAL++T     +       +  L    T+ S         T
Sbjct: 1951 VTSSKATPSSSPG-TATALPALRSTATTPTATSVTPIPSSSLGTTWTRLS--------QT 2001

Query: 306  AGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPL 365
              P     T+ +S A   ST       + ++ T+  +     V+   STP T      P 
Sbjct: 2002 TTP-----TATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPT 2056

Query: 366  ISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGP 425
             +T   ++ P  S       PV  S T  P T         V+P S+          PG 
Sbjct: 2057 TTTTGFTATPSSSPGTALTPPVWISTTTTPTTRG-----STVTPSSI----------PGT 2101

Query: 426  NHTSNSSNASNATVVPQN----SSARSTCSLTPAL 456
             HT+     +  TV   +    SS+  T    P+L
Sbjct: 2102 THTATVLTTTTTTVATGSMATPSSSTQTSGTPPSL 2136



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 61/290 (21%), Positives = 113/290 (38%), Gaps = 37/290 (12%)

Query: 196  ATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAP------------PTSASAVPVS 243
            +T+  +S ++T+G   VS + TTP+ +S S   P S+P             T+ +A   +
Sbjct: 2483 STATASSTQATAGTPHVSTTATTPTVTS-SKATPFSSPGTATALPALRSTATTPTATSFT 2541

Query: 244  PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLT----------AAVTQ 293
             +P S +        L +   P    +    +S  +    + VLT          +  T 
Sbjct: 2542 AIPSSSLGTTW--TRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATP 2599

Query: 294  ASLQSIIH--KFLTAGPSAFNITSLISQAAQ------LSTQAQPSNQSPMSLTSDASSPR 345
            +S     H  K LT   + F  T   S          +ST   P+ +   S  + +S P 
Sbjct: 2600 SSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRG--STVTPSSIPG 2657

Query: 346  SYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHE 405
            +  +P + T  T TV    + +TP  S+Q   + P +     + +AT          G  
Sbjct: 2658 TTHTPTVLTTTTTTVATGSM-ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTT 2716

Query: 406  PVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPA 455
            P+ P  L  +++  + +      S++   ++   VP  ++     SL+P+
Sbjct: 2717 PIPP-VLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPS 2765



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 68/292 (23%), Positives = 110/292 (37%), Gaps = 51/292 (17%)

Query: 191  VMQATATSGFASGK-STSGDKPVSHSCTTPSTSSASGLNPT-SAPPTSASAVPV------ 242
            V+  TAT+  A+G  +T    P +   T   T++ +G   T S+ P +A  +PV      
Sbjct: 2582 VLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTT 2641

Query: 243  ------SPVPQSPIPPLLQDPNLLRQLLPALQA-TLQLNNSNVDISKINEVLTAAVTQAS 295
                  S V  S IP     P +L      +   ++   +S+   S     LT   T   
Sbjct: 2642 TPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTAT--- 2698

Query: 296  LQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPR---SYVSPRI 352
              +I     T  PS+   T+ I                P  LT+ A++P    S V+P  
Sbjct: 2699 --TITATGSTTNPSSTPGTTPI----------------PPVLTTTATTPAATSSTVTPSS 2740

Query: 353  STPQTNTVPIKPLISTPPVSSQPKVSTPVVK-------QGPVSQSATQQPVTADKQQGHE 405
            +   T+T P+    +T    S    S   V+        G +  +   +P T      H 
Sbjct: 2741 ALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS---HT 2797

Query: 406  PVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA--RSTCSLTPA 455
            P +     + S+    SP P+  +  S  S  T  P ++ A  R+T + TP+
Sbjct: 2798 PAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPS 2849



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 61/280 (21%), Positives = 105/280 (37%), Gaps = 23/280 (8%)

Query: 193  QATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTS-ASAVPVSPVPQSPIP 251
            ++TATS      ST G        TT   ++ S ++P+S P T+  S V  +    +   
Sbjct: 4320 KSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRAT 4379

Query: 252  PLLQDPN-------LLRQLLPALQATLQLNNSNVDISK------INEVLTAAVTQASLQS 298
                 P+       +L +L  A   T     +    S       + E+ T A T AS  S
Sbjct: 4380 SSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGS 4439

Query: 299  IIHKFLTAGPSAF-NITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQT 357
                  TA PS+    T ++++ +  +T   P+  +  + ++ A++   +VS   +TP  
Sbjct: 4440 ------TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV 4493

Query: 358  NTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 417
             +    P  S    ++ P + +        S +A                +  +   S++
Sbjct: 4494 TSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTA 4553

Query: 418  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALA 457
              S +P   HTS    A+  T     S A  T S TP  A
Sbjct: 4554 TPSSTPETVHTSTVLTATATTTGATGSVA--TPSSTPGTA 4591



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 64/253 (25%), Positives = 94/253 (37%), Gaps = 30/253 (11%)

Query: 201  ASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +S   TSG  P   +  T  T++ S  NP+S P T+            PIPP+L      
Sbjct: 3381 SSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTT------------PIPPVL----TT 3424

Query: 261  RQLLPALQATLQLNNSNVDISKINEV--LTAAVTQASL-QSIIHKFLTAGPSAFNITSLI 317
                PA  ++    +S +  +    V   TA     SL  S  H   TA  SA   TS I
Sbjct: 3425 TATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSA---TSGI 3481

Query: 318  SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP----PVSS 373
                 ++  +  ++ +P + TS        +S    + +T   P  P  +TP      S 
Sbjct: 3482 LGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSR 3541

Query: 374  QPKVSTPVVKQGP--VSQSATQQPVTADKQQGHEPVSPRS--LQRSSSQRSPSPGPNHTS 429
                +TP   +    +  S T  P+T     G EP    S  L  S     PS G   T 
Sbjct: 3542 TTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTY 3601

Query: 430  NSSNASNATVVPQ 442
            ++  A+   V  Q
Sbjct: 3602 SNIRAAGGAVCEQ 3614



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 60/290 (20%), Positives = 113/290 (38%), Gaps = 37/290 (12%)

Query: 196  ATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAP------------PTSASAVPVS 243
            +T+  +S ++T+G   VS + TTP+ +S S   P S+P             T+ +A   +
Sbjct: 3740 STATASSTQATAGTPHVSTTATTPTVTS-SKATPFSSPGTATALPALRSTATTPTATSFT 3798

Query: 244  PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLT----------AAVTQ 293
             +P S +        L +   P    +    +S  + +  + VLT          +  T 
Sbjct: 3799 AIPSSSLGTTW--TRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATP 3856

Query: 294  ASLQSIIH--KFLTAGPSAFNITSLISQAAQ------LSTQAQPSNQSPMSLTSDASSPR 345
            +S     H  K  T   + F +T   S          +ST   P+     S  + +S P 
Sbjct: 3857 SSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSG--STVTPSSVPG 3914

Query: 346  SYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHE 405
            +  +P + T  T TV    + +TP  S+Q   + P +     + +AT          G  
Sbjct: 3915 TTHTPTVLTTTTTTVATGSM-ATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTT 3973

Query: 406  PVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPA 455
            P+ P  L  +++  + +      S++   ++   VP  ++     SL+P+
Sbjct: 3974 PIPP-VLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPS 4022



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 58/273 (21%), Positives = 107/273 (39%), Gaps = 30/273 (10%)

Query: 205  STSGDKPVSHSCTTPSTS--SASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQ 262
            +T+    V+ S  TPS+S  +A+ L    +  T+ +A  V+P+P S +        L + 
Sbjct: 1944 TTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTW--TRLSQT 2001

Query: 263  LLPALQATLQLNNSNVDISKINEVLTA----------AVTQASLQSIIH--KFLTAGPSA 310
              P    +    +S  + +  + VLTA            T +S     H  K  T   + 
Sbjct: 2002 TTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTG 2061

Query: 311  FNIT------SLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKP 364
            F  T      + ++    +ST   P+ +   S  + +S P +  +  + T  T TV    
Sbjct: 2062 FTATPSSSPGTALTPPVWISTTTTPTTRG--STVTPSSIPGTTHTATVLTTTTTTVATGS 2119

Query: 365  LISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG 424
            + +TP  S+Q   + P +     + +AT          G  P+ P     +++  +P+  
Sbjct: 2120 M-ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPP---VLTTTATTPAAT 2175

Query: 425  PNHTSNSS--NASNATVVPQNSSARSTCSLTPA 455
             N  + SS    ++   VP   +     SL P+
Sbjct: 2176 SNTVTPSSALGTTHTPPVPNTMATTHGRSLPPS 2208



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 62/253 (24%), Positives = 92/253 (36%), Gaps = 30/253 (11%)

Query: 201  ASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +S   TSG  P   +  T  T++ S  NP+S P T            +PIPP+L      
Sbjct: 2681 SSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGT------------TPIPPVL----TT 2724

Query: 261  RQLLPALQATLQLNNSNVDISKINEV--LTAAVTQASLQ-SIIHKFLTAGPSAFNITSLI 317
                PA  ++    +S +  +    V   TA     SL  S  H   TA  SA   TS  
Sbjct: 2725 TATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSA---TSGT 2781

Query: 318  SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP----PVSS 373
                 ++  +  ++ +P + T         +S    + +T   P  P  +TP      S 
Sbjct: 2782 LGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSR 2841

Query: 374  QPKVSTPVVKQGP--VSQSATQQPVTADKQQGHEPVSPRS--LQRSSSQRSPSPGPNHTS 429
                +TP   +    +  S T  P+T     G EP    S  L  S     PS G   T 
Sbjct: 2842 TTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTY 2901

Query: 430  NSSNASNATVVPQ 442
            ++  A+   V  Q
Sbjct: 2902 SNIRAAGGAVCEQ 2914



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 62/253 (24%), Positives = 93/253 (36%), Gaps = 30/253 (11%)

Query: 201  ASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPV-------PQSPIPPL 253
            +S   TSG  P   +  T  T++ S  NP+S P T+    P+ PV       P +    +
Sbjct: 2124 SSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTT----PIPPVLTTTATTPAATSNTV 2179

Query: 254  LQDPNLLRQLLPALQATLQLNNS-NVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 312
                 L     P +  T+   +  ++  S  + V TA  +  S   I+       PS   
Sbjct: 2180 TPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATS--GILGTTHITEPS--T 2235

Query: 313  ITSLISQAAQLSTQ-AQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPV 371
            +TS    A   +TQ + P+  SP   +    SP    SP  +TP   T   +   +  P 
Sbjct: 2236 VTSHTLAATTGTTQHSTPALSSPHPSSRTTESP---PSPGTTTPGHTTATSRTTATATPS 2292

Query: 372  SSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS--LQRSSSQRSPSPGPNHTS 429
             ++     P         S T  P+T     G EP    S  L  S     PS G   T 
Sbjct: 2293 KTRTSTLLP--------SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTY 2344

Query: 430  NSSNASNATVVPQ 442
            ++  A+   V  Q
Sbjct: 2345 SNIRAAGGAVCEQ 2357



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 64/261 (24%), Positives = 91/261 (34%), Gaps = 46/261 (17%)

Query: 201  ASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 260
            +S   TSG  P   +  T  T++ S  NP+S P T            +PIPP+L      
Sbjct: 3938 SSSTQTSGTPPSLITTATTITATGSTTNPSSTPGT------------TPIPPVL----TT 3981

Query: 261  RQLLPALQATLQLNNSNVDISKINEV--LTAAVTQASLQ-SIIHKFLTAGPSAFNITSLI 317
                PA  ++    +S +  +    V   TA     SL  S  H   TA  SA + T   
Sbjct: 3982 TATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGT 4041

Query: 318  SQAAQLST--------------QAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIK 363
            +   + ST               + P+  SP   +    SP    SP  +TP   T   +
Sbjct: 4042 THITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESP---PSPGTTTPGHTTATSR 4098

Query: 364  PLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS--LQRSSSQRSP 421
               +  P  ++     P         S T  P+T     G EP    S  L  S     P
Sbjct: 4099 TTATATPSKTRTSTLLP--------SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGP 4150

Query: 422  SPGPNHTSNSSNASNATVVPQ 442
            S G   T ++  A+   V  Q
Sbjct: 4151 SGGDFDTYSNIRAAGGAVCEQ 4171



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 59/265 (22%), Positives = 94/265 (35%), Gaps = 57/265 (21%)

Query: 196  ATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQ 255
            +T+  +S ++T+G   V  S  T  T  +S   P+S+P T+ +                 
Sbjct: 3182 STATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATA----------------- 3224

Query: 256  DPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITS 315
                    LPAL++T     +    +  +  L  A T+ S         T  P     T+
Sbjct: 3225 --------LPALRSTATTPTATSVTAIPSSSLGTAWTRLS--------QTTTP-----TA 3263

Query: 316  LISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQP 375
             +S A   ST       + ++ T+  +     V+   STP T      P  +T   ++ P
Sbjct: 3264 TMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATP 3323

Query: 376  KVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNAS 435
              S       PV  S T  P T         V+P S+          PG  HT+     +
Sbjct: 3324 SSSPGTALTPPVWISTTTTPTTRG-----STVTPSSI----------PGTTHTATVLTTT 3368

Query: 436  NATVVPQN----SSARSTCSLTPAL 456
              TV   +    SS+  T    P+L
Sbjct: 3369 TTTVATGSMATPSSSTQTSGTPPSL 3393



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 71/302 (23%), Positives = 112/302 (37%), Gaps = 40/302 (13%)

Query: 195  TATSGF-ASGKSTSGDKP----VSHSCTTPS------TSSASGLNPTSAPPTSASAVPVS 243
            TAT+G  A   ST G  P    ++ + TTP+      TSS+S    T+ P  +++A   +
Sbjct: 3006 TATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKST 3065

Query: 244  PVPQSPIPPL-LQDPNLLRQLLPALQATLQL--NNSNVDISKINEVLTA-AVTQASLQSI 299
                +PIP   L     L +      AT+     +S  + +  + VLT  A T  +  S+
Sbjct: 3066 ATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSM 3125

Query: 300  IHKFLTAGPS--AFNITSLISQAAQLSTQAQPSNQS-----------------PMSLTSD 340
                 T G +     +T+  +  A     A PS+                   P   T+ 
Sbjct: 3126 STPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTAT 3185

Query: 341  ASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADK 400
            ASS R+          T T P   + S    SS P  +T +      + + T   VTA  
Sbjct: 3186 ASSTRATAGTLKVLTSTATTP-TVISSRATPSSSPGTATALPALRSTATTPTATSVTAIP 3244

Query: 401  QQGHEPVSPRSLQRSS-----SQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPA 455
                     R  Q ++     S  +PS  P     S+  +  T   + + + +T S TP 
Sbjct: 3245 SSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPG 3304

Query: 456  LA 457
             A
Sbjct: 3305 TA 3306



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 67/281 (23%), Positives = 109/281 (38%), Gaps = 42/281 (14%)

Query: 195  TATSGFASGKSTSGDKPV----SHSCTTP------STSSASGLNPTSAPPTSASAVPVSP 244
            TAT    +  ST G  P+    + + TTP      +TSS+S    T+ P  +++A   + 
Sbjct: 4691 TATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTA 4750

Query: 245  VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVL---TAAVTQASLQSIIH 301
               +PIP            +PA   T     S +  S   E     T   T A++    +
Sbjct: 4751 TSFTPIP---SSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATN 4807

Query: 302  KFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVP 361
               TA PS+   T+ I    +L+T A  +  +  + T  ++   +++   ++ P T    
Sbjct: 4808 S--TATPSSTLGTTRI--LTELTTTATTTAATGSTATLSSTPGTTWI---LTEPSTIATV 4860

Query: 362  IKPLISTPPVSSQ-PKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRS 420
            + P  ST   SS      TP V    V+  AT    TA        V         + R+
Sbjct: 4861 MVPTGSTATASSTLGTAHTPKV----VTTMATMPTATASTVPSSSTV--------GTTRT 4908

Query: 421  PSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFS 461
            P+  P      S+    +V   +SS  +T   T   ++HFS
Sbjct: 4909 PAVLP------SSLPTFSVSTVSSSVLTTLRPTGFPSSHFS 4943



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 16/51 (31%), Positives = 25/51 (49%), Gaps = 1/51 (1%)

Query: 203  GKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP-QSPIPP 252
            G + +  K ++ +   P +       PT  PPT++ A PVS  P  +P PP
Sbjct: 5240 GTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPP 5290


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 74/282 (26%), Positives = 111/282 (39%), Gaps = 25/282 (8%)

Query: 193 QATATSGFASGKSTSG---DKPVSHSCTTPSTSS-ASGLNPTSAPPTSASAVPVSPVPQS 248
           QAT + G  + ++T       P+S   T P  +  A  L P  APP+  ++ P+SP+  +
Sbjct: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL-AT 422

Query: 249 PIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVT-QASLQSIIHKFLTAG 307
           P P   Q PN L   L  LQA      S    +  +   +  V+  A+  S     L A 
Sbjct: 423 PSP---QAPNALAVHL--LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477

Query: 308 PSAFNITSLISQAAQLSTQAQPSNQSPMSLTS---DASSPRSYVSPRISTPQTNTVPIKP 364
           P    +      +  +S  A P  Q+P  L +     + P     P ++TP    +P  P
Sbjct: 478 P--LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535

Query: 365 LISTPPVSSQPKVSTPVVKQGPVSQSATQ-QPVTADKQQGHEPVSPRSLQRSSSQRSPSP 423
                     P  S P+    P++    Q  PV A       P  P S    + +R P+P
Sbjct: 536 ASFPGQAPFSPSASLPM---SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 592

Query: 424 GPNHTSNSSNASNATV----VPQNSSARSTCSLTPALAAHFS 461
           GP+ + +    + A       P + S  ST S  P LA H S
Sbjct: 593 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS-GPDLAGHSS 633



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 59/238 (24%), Positives = 89/238 (37%), Gaps = 50/238 (21%)

Query: 219 PSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNV 278
           PS    +  +P ++PP S SA P S  P S   P LQ P       P+  A+  ++ S  
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-------PSPPASPPMSPSAT 496

Query: 279 DISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLT 338
              +    L A                             Q A+   QA P+  +P  L 
Sbjct: 497 PPPQAPPPLAAPPL--------------------------QLAKPPPQAPPALATP-PLQ 529

Query: 339 SDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTA 398
           +  S P S+      +P   ++P+ PL +TPP  + P ++ P+++  P        P + 
Sbjct: 530 ALPSPPASFPGQAPFSPSA-SLPMSPL-ATPPPQAPPVLAAPLLQVPP------SPPASP 581

Query: 399 DKQQGHEPVSPRSLQRSSSQR-------SPSPGPNHTSNSSNASNATVVPQNSSARST 449
             Q    P +P      S  R        P P P+  S SS  S   +   +SSA ST
Sbjct: 582 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR-SPSSTLSGPDLAGHSSSATST 638



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 60/261 (22%), Positives = 88/261 (33%), Gaps = 12/261 (4%)

Query: 202 SGKSTSGDKPVSHSCTTPSTSSASGLNPTSA-PPTSASAVPVSPVPQSPIPPLLQDPNLL 260
           SG S  G        + P       L P    PP   +A  + P+  SP+        L 
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ 314

Query: 261 RQLLPALQATLQLNNSNVDI-SKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQ 319
            Q  P L AT   ++    + + +     +     SLQ++      A P +   TSL S 
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP--PATPPSQATTSLGSP 372

Query: 320 AAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQT--NTVPIKPLISTPPVSSQPKV 377
             Q +    PS       T    +P +   P +  P +   + P+ PL +  P    P  
Sbjct: 373 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP--QAPNA 430

Query: 378 STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA 437
               + Q P S   +             PVSP +   S +  S +  P     S  AS  
Sbjct: 431 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS-- 488

Query: 438 TVVPQNSSARSTCSLTPALAA 458
              P + SA       P LAA
Sbjct: 489 --PPMSPSATPPPQAPPPLAA 507



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 42/147 (28%), Positives = 63/147 (42%), Gaps = 16/147 (10%)

Query: 328 QPSNQSPMSLTSDASSP-RSYVSPRISTPQTNTVPIKP------LISTPPVSSQPKVSTP 380
           +P+++S  S  +  SSP RS  S R  TP+    P +P       +  P V+   K + P
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSAR-GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294

Query: 381 VVKQGPVSQS--ATQQPVTADKQQGHE--PVSPRSLQRSSSQRSPSP-GPNHTSNSSNAS 435
            +  GP+S S  AT  P  A + Q     P +P S   +    +P P  P   S   +  
Sbjct: 295 AL--GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ 352

Query: 436 NATVVPQNSSARSTCSL-TPALAAHFS 461
                P    +++T SL +P L A  S
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHS 379


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 74/282 (26%), Positives = 111/282 (39%), Gaps = 25/282 (8%)

Query: 193 QATATSGFASGKSTSG---DKPVSHSCTTPSTSS-ASGLNPTSAPPTSASAVPVSPVPQS 248
           QAT + G  + ++T       P+S   T P  +  A  L P  APP+  ++ P+SP+  +
Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL-AT 383

Query: 249 PIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVT-QASLQSIIHKFLTAG 307
           P P   Q PN L   L  LQA      S    +  +   +  V+  A+  S     L A 
Sbjct: 384 PSP---QAPNALAVHL--LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 438

Query: 308 PSAFNITSLISQAAQLSTQAQPSNQSPMSLTS---DASSPRSYVSPRISTPQTNTVPIKP 364
           P    +      +  +S  A P  Q+P  L +     + P     P ++TP    +P  P
Sbjct: 439 P--LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496

Query: 365 LISTPPVSSQPKVSTPVVKQGPVSQSATQ-QPVTADKQQGHEPVSPRSLQRSSSQRSPSP 423
                     P  S P+    P++    Q  PV A       P  P S    + +R P+P
Sbjct: 497 ASFPGQAPFSPSASLPM---SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553

Query: 424 GPNHTSNSSNASNATV----VPQNSSARSTCSLTPALAAHFS 461
           GP+ + +    + A       P + S  ST S  P LA H S
Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS-GPDLAGHSS 594



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 59/238 (24%), Positives = 89/238 (37%), Gaps = 50/238 (21%)

Query: 219 PSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNV 278
           PS    +  +P ++PP S SA P S  P S   P LQ P       P+  A+  ++ S  
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-------PSPPASPPMSPSAT 457

Query: 279 DISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLT 338
              +    L A                             Q A+   QA P+  +P  L 
Sbjct: 458 PPPQAPPPLAAPPL--------------------------QLAKPPPQAPPALATP-PLQ 490

Query: 339 SDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTA 398
           +  S P S+      +P   ++P+ PL +TPP  + P ++ P+++  P        P + 
Sbjct: 491 ALPSPPASFPGQAPFSPSA-SLPMSPL-ATPPPQAPPVLAAPLLQVPP------SPPASP 542

Query: 399 DKQQGHEPVSPRSLQRSSSQR-------SPSPGPNHTSNSSNASNATVVPQNSSARST 449
             Q    P +P      S  R        P P P+  S SS  S   +   +SSA ST
Sbjct: 543 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR-SPSSTLSGPDLAGHSSSATST 599



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 56/276 (20%), Positives = 96/276 (34%), Gaps = 40/276 (14%)

Query: 208 GDKPVSH------SCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLR 261
           G KP++         T P ++  +G   TS PP S       P   +   P+        
Sbjct: 54  GRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASG 113

Query: 262 QLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIH---KFLTAGPSAFNITSLIS 318
              P       L    + IS    V     T+A  +S +    +  T+GP+    +  ++
Sbjct: 114 TTRPG-----PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 168

Query: 319 QAAQL------------STQAQPSNQSPMSLTSDAS-------SPRSYVSPRISTPQTNT 359
           + ++             S + +P  + P    S AS       SP +   P         
Sbjct: 169 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228

Query: 360 VPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQR 419
                  S  P+SS P  S P  +  P + +   QP    K +G + + P  +       
Sbjct: 229 ASRSLSSSATPLSS-PARSGPSARGTPRAPAHPSQP----KPKGLQALRPPQVTPPRKDA 283

Query: 420 SPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPA 455
           +P+ GP   S+S  A+ +   P + SA  +    P+
Sbjct: 284 APALGP--LSSSPLATPSPSAPPSPSAPPSLQTLPS 317


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 18/42 (42%), Positives = 30/42 (71%)

Query: 131 SADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKE 172
           +  +W+E+ ++ GK YYYN RT  S WEKP+E  E+E+ +++
Sbjct: 410 AVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEK 451



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 14/26 (53%), Positives = 16/26 (61%)

Query: 135 WSEHISSSGKKYYYNCRTEVSQWEKP 160
           W E+ +  GK YYYN RT  S W KP
Sbjct: 137 WVENKTPDGKVYYYNARTRESAWTKP 162



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 13/129 (10%)

Query: 290 AVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVS 349
           A  QA +Q+ +   + A     +  +  S A  +ST    S+ +P S TS  ++  S V+
Sbjct: 237 AQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTST--SSSTPSSTTSTTTTATS-VA 293

Query: 350 PRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQ-QPVTADKQQGHEPVS 408
             +STP T          TP  SS   V+TP V     + +AT  Q V     Q   P  
Sbjct: 294 QTVSTPTTQD-------QTP--SSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAV 344

Query: 409 PRSLQRSSS 417
           P S+ + ++
Sbjct: 345 PHSVPQPTT 353


>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
           sapiens]
          Length = 1098

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 18/42 (42%), Positives = 30/42 (71%)

Query: 131 SADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKE 172
           +  +W+E+ ++ GK YYYN RT  S WEKP+E  E+E+ +++
Sbjct: 431 AVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEK 472



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 52/258 (20%), Positives = 88/258 (34%), Gaps = 11/258 (4%)

Query: 135 WSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQA 194
           W E+ +  GK YYYN RT  S W KP + ++  Q+ +    +A  +  + +   +   QA
Sbjct: 137 WVENKTPDGKVYYYNARTRESAWTKP-DGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQA 195

Query: 195 TATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLL 254
            A +   +                 + + A       A   + +   V    Q+ +    
Sbjct: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQA 255

Query: 255 QDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQ-ASLQSIIHKFLTAGPSAFNI 313
              +      PA   +   ++S    +        +V Q  S  +   +  ++  S    
Sbjct: 256 VGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATP 315

Query: 314 TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPL-------- 365
           T  +S  A  +T  Q   Q P   T   + P S   P  + P    V + P         
Sbjct: 316 TVSVSTPAPTATPVQTVPQ-PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMP 374

Query: 366 ISTPPVSSQPKVSTPVVK 383
           I  P V+    VS P VK
Sbjct: 375 IPLPGVAMMQIVSCPYVK 392



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 13/129 (10%)

Query: 290 AVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVS 349
           A  QA +Q+ +   + A     +  +  S A  +ST    S+ +P S TS  ++  S V+
Sbjct: 237 AQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTST--SSSTPSSTTSTTTTATS-VA 293

Query: 350 PRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQ-QPVTADKQQGHEPVS 408
             +STP T          TP  SS   V+TP V     + +AT  Q V     Q   P  
Sbjct: 294 QTVSTPTTQD-------QTP--SSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAV 344

Query: 409 PRSLQRSSS 417
           P S+ + ++
Sbjct: 345 PHSVPQPTT 353


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 70/297 (23%), Positives = 112/297 (37%), Gaps = 46/297 (15%)

Query: 194  ATATSGFASGKSTSG---DKPVSHSCTT------PSTSSASGLNPTSAPPTSASAVPVSP 244
            +T T  F    +TSG   +   SHS TT      PST+SA    PTS   +S  +   + 
Sbjct: 3478 STQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY-HSSPGSTATTH 3536

Query: 245  VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL 304
             P S       + +           T+ L   +     + E  T+ ++  S+++      
Sbjct: 3537 FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET------ 3590

Query: 305  TAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST---------- 354
            TA P +     L    ++ ST    S +SP +  S AS+  S VS   +T          
Sbjct: 3591 TALPGSTTTPGL----SEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHT 3646

Query: 355  ---PQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGH-----EP 406
               P + T P     ST   SS     T ++     +  ++Q+  T+    G       P
Sbjct: 3647 TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSP 3706

Query: 407  VSPRSLQ--RSSSQRSPSPGPNHT------SNSSNASNATVVPQNSSARSTCSLTPA 455
             S  +L   + S+    SPG  HT      + SS    A+    +S+     +L+PA
Sbjct: 3707 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 3763



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 70/297 (23%), Positives = 110/297 (37%), Gaps = 46/297 (15%)

Query: 194  ATATSGFASGKSTSG---DKPVSHSCTT------PSTSSASGLNPTSAPPTSASAVPVSP 244
            +T T  F    +TSG   +   SHS TT      PST+SA    PTS   +S  +   + 
Sbjct: 838  STQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY-HSSPGSTATTH 896

Query: 245  VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL 304
             P S       + +           T+ L   +     + E  T+ ++  S+++      
Sbjct: 897  FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET------ 950

Query: 305  TAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST---------- 354
            TA P +     L    ++ ST    S +SP +  S AS+  S VS   +T          
Sbjct: 951  TALPGSTTTPGL----SERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHT 1006

Query: 355  ---PQTNTVPIKPLISTPPVSSQPKVSTPVV-----KQGPVSQSATQQPVTADKQQGHEP 406
               P + T P     ST   SS     T ++       GP  +S T    +        P
Sbjct: 1007 TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSP 1066

Query: 407  VSPRSLQ--RSSSQRSPSPGPNHT------SNSSNASNATVVPQNSSARSTCSLTPA 455
             S  +L   + S+    +PG  HT      + SS    A+    +S+     +L+PA
Sbjct: 1067 GSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 1123



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 69/297 (23%), Positives = 110/297 (37%), Gaps = 46/297 (15%)

Query: 194  ATATSGFASGKSTSG---DKPVSHSCTT------PSTSSASGLNPTSAPPTSASAVPVSP 244
            +T T  F    + SG   +   SHS TT      PST+SA    PTS   +S  +   + 
Sbjct: 1921 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSY-HSSPGSTATTH 1979

Query: 245  VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL 304
             P S       + +           T+ L   +     + E  T+ ++  S+++      
Sbjct: 1980 FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET------ 2033

Query: 305  TAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST---------- 354
            TA P +     L    ++ ST    S +SP +  S AS+  S VS   +T          
Sbjct: 2034 TALPGSTTTPGL----SEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHT 2089

Query: 355  ---PQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGH-----EP 406
               P + T P     ST   SS     T ++     +   +Q+  T+    G       P
Sbjct: 2090 TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSP 2149

Query: 407  VSPRSLQ--RSSSQRSPSPGPNHT------SNSSNASNATVVPQNSSARSTCSLTPA 455
             S  +L   + S+    SPG  HT      + SS    A+    +S+     +L+PA
Sbjct: 2150 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 2206



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 66/276 (23%), Positives = 105/276 (38%), Gaps = 31/276 (11%)

Query: 194  ATATSGFASGKSTSG---DKPVSHSCTT------PSTSSASGLNPTSAPPTSASAVPVSP 244
            +T T  F    + SG   +   SHS TT      PST+SA    PTS   +S  ++  + 
Sbjct: 4754 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSY-HSSPGSIATTH 4812

Query: 245  VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL 304
             P+S       + +      P       L        +I E  T  ++  S+++ +    
Sbjct: 4813 FPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTA 4872

Query: 305  TAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASS--PRSYVSPRISTPQTNTVPI 362
            T    +   T L S     S+++     SP S+TS + S  P S  S   ST  T   P 
Sbjct: 4873 TTPGLSAKSTILYS-----SSRSPDQTLSPASMTSSSISGEPTSLYSQAEST-HTTAFPA 4926

Query: 363  KPLIS-----TPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQ---GHEPVSPRS--- 411
                S     +    S+P  +   +  G ++ S+  Q  T    Q       VSP S   
Sbjct: 4927 STTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTV 4986

Query: 412  --LQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 445
              L   S+    SPG   T+  S+++  ++  Q S+
Sbjct: 4987 PGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQST 5022



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 55/266 (20%), Positives = 95/266 (35%), Gaps = 35/266 (13%)

Query: 194  ATATSGFASGKSTSGDKPVS-------HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP 246
            +T +SG +   +TS  +P S        S TTP  S  S  + +S   T  + +P S   
Sbjct: 984  STTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 1043

Query: 247  QSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL-T 305
              P                + ++T   ++S    + ++   T A++     +  H    +
Sbjct: 1044 SGP----------------SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGS 1087

Query: 306  AGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPL 365
               + F  ++  S   + ST+   S  SP +  S ASS     SP +    T        
Sbjct: 1088 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS----TSPGLQGEST-------A 1136

Query: 366  ISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGP 425
              T P S+    S P     PV +S T           H P S  +   S         P
Sbjct: 1137 FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP 1196

Query: 426  NHTSNSSNASNATVVPQNSSARSTCS 451
            + +  + +++++T   +  S  S  S
Sbjct: 1197 DASGTTPSSAHSTTSGRGESTTSRIS 1222



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 57/272 (20%), Positives = 96/272 (35%), Gaps = 24/272 (8%)

Query: 195  TATSGFASGKSTSGDKPVS-------HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQ 247
            T +SG +   STS  +P S        S TTP  S  S  + +S   T  + +P S    
Sbjct: 2542 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 2601

Query: 248  SPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAG 307
             P        +      P    T     S   +S   E  T   +  S  + +       
Sbjct: 2602 GP-----SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL------- 2649

Query: 308  PSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLIS 367
               F  ++  S   + ST+   S  SP +  S ASS    +    +T QT+        S
Sbjct: 2650 ---FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPS 2706

Query: 368  TPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 427
             P  ++ P   +    + P S   T  P ++      E  +       +S  +PS   + 
Sbjct: 2707 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 2766

Query: 428  TSNSSNASNATVVPQNSSARST--CSLTPALA 457
            TS    ++ + + P ++   +    + TP L+
Sbjct: 2767 TSGRGESTTSRISPGSTEITTLPGSTTTPGLS 2798



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 64/283 (22%), Positives = 112/283 (39%), Gaps = 23/283 (8%)

Query: 195  TATSGFASGKSTSGDKPVS-HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPL 253
            + TSG     +T    P S  +   P +++ SG    S    S++   +S  P S    L
Sbjct: 4543 STTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAP-STTSAL 4601

Query: 254  LQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSII--HKFLTAGPSAF 311
            +++P       P   AT    +S+    +  E   +  +Q +  +I+   +  T+     
Sbjct: 4602 VEEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGE 4660

Query: 312  NITSLISQAAQLSTQAQPSNQSP----MSLT---SDASSPRSYVSPRIST----PQTNTV 360
            + TS IS  +  +T    S  +P     S T   S +S+P ++ S   +T     ++ TV
Sbjct: 4661 STTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTV 4720

Query: 361  PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRS 420
               P ++T    S  + +T     G V +S          Q  H P S  +  RS   R+
Sbjct: 4721 HSSP-VATATTPSPARSTT----SGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 4775

Query: 421  PSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSEN 463
                  HT +S  ++ + +V + +S  S  S       HF E+
Sbjct: 4776 SHSSTTHTISSPPSTTSALVEEPTSYHS--SPGSIATTHFPES 4816



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 57/265 (21%), Positives = 89/265 (33%), Gaps = 33/265 (12%)

Query: 194  ATATSGFASGKSTSGDKPVS-------HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP 246
            +T +SG +   +TS  +P S        S TTP  S  S  + +S   T  + +P S   
Sbjct: 2067 STTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 2126

Query: 247  QSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTA 306
              P        +      P    T     S   +S   E  T   +  S  + +      
Sbjct: 2127 SGP-----SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL------ 2175

Query: 307  GPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLI 366
                F  ++  S   + ST+   S  SP +  S ASS     SP +    T         
Sbjct: 2176 ----FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS----TSPGLQGEST-------AF 2220

Query: 367  STPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPN 426
             T P S+    S P     PV +S T           H P S  +   S         P+
Sbjct: 2221 QTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPD 2280

Query: 427  HTSNSSNASNATVVPQNSSARSTCS 451
             +  + +++++T   +  S  S  S
Sbjct: 2281 ASGTTPSSAHSTTSGRGESTTSRIS 2305



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 54/266 (20%), Positives = 94/266 (35%), Gaps = 35/266 (13%)

Query: 194  ATATSGFASGKSTSGDKPVS-------HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP 246
            +T +SG +   +TS  +P S        S TTP  S  S  + +S   T  + +P S   
Sbjct: 3624 STTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 3683

Query: 247  QSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL-T 305
                               + ++T   ++S    + ++   T A++     +  H    +
Sbjct: 3684 SGS----------------SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGS 3727

Query: 306  AGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPL 365
               + F  ++  S   + ST+   S  SP +  S ASS     SP +    T        
Sbjct: 3728 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS----TSPGLQGEST-------A 3776

Query: 366  ISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGP 425
              T P S+    S P     PV +S T           H P S  +   S         P
Sbjct: 3777 FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP 3836

Query: 426  NHTSNSSNASNATVVPQNSSARSTCS 451
            + +  + +++++T   +  S  S  S
Sbjct: 3837 DASGTTPSSAHSTTSGRGESTTSRIS 3862



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 65/287 (22%), Positives = 105/287 (36%), Gaps = 27/287 (9%)

Query: 180  SFPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCTT--PSTSSASGLNPTSAPPT-S 236
            +FP      +  + AT T+     +ST+       + TT  P+ S+ SGL   S P   S
Sbjct: 2916 AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLS 2975

Query: 237  ASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASL 296
             S+   + +P SP  P L + +           T   +  + D +     L+ A T +S 
Sbjct: 2976 PSSTETTTLPGSPTTPSLSEKS----------TTFYTSPRSPDAT-----LSPATTTSSG 3020

Query: 297  QSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQ 356
             S       + P + + T+        ST     +Q P +  S   S  + +SP  +T  
Sbjct: 3021 VSEESSTSHSQPGSTHTTAFPD-----STTTSGLSQEPTASHSSQGSTEATLSPGSTTAS 3075

Query: 357  TNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS--LQR 414
            +         S+P  +    +    +  G V  S      T        P S  S  LQ 
Sbjct: 3076 SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQE 3135

Query: 415  SSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFS 461
             S+     P  + T+ S   + A  V  +++  S  S TP    HFS
Sbjct: 3136 ESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP--TTHFS 3180



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 64/287 (22%), Positives = 105/287 (36%), Gaps = 27/287 (9%)

Query: 180  SFPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCT--TPSTSSASGLNPTSAPPT-S 236
            +FP      +  + AT T+     +ST+       + T  +P+ S+ SGL   S P   S
Sbjct: 1359 AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLS 1418

Query: 237  ASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASL 296
             S+   + +P SP  P L + +           T   +  + D +     L+ A T +S 
Sbjct: 1419 PSSTETTTLPGSPTTPSLSEKS----------TTFYTSPRSPDAT-----LSPATTTSSG 1463

Query: 297  QSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQ 356
             S       + P + + T+        ST     +Q P +  S   S  + +SP  +T  
Sbjct: 1464 VSEESSTSHSQPGSTHTTAFPD-----STTTSDLSQEPTTSHSSQGSTEATLSPGSTTAS 1518

Query: 357  TNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS--LQR 414
            +         S+P  +    +    +  G V  S      T        P S  S  LQ 
Sbjct: 1519 SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQE 1578

Query: 415  SSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFS 461
             S+     P  + T+ S   + A  V  +++  S  S TP    HFS
Sbjct: 1579 ESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP--TTHFS 1623



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 64/287 (22%), Positives = 106/287 (36%), Gaps = 27/287 (9%)

Query: 180  SFPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCT--TPSTSSASGLNPTSAPPT-S 236
            +FP      +  + AT T+     +ST+       + T  +P+ S+ SGL   S P   S
Sbjct: 3999 AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLS 4058

Query: 237  ASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASL 296
             S+   + +P SP  P L + +           T   +  + D +     L+ A T +S 
Sbjct: 4059 PSSTETTTLPGSPTTPSLSEKS----------TTFYTSPRSPDAT-----LSPATTTSSG 4103

Query: 297  QSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQ 356
             S       + P + + T+        ST     +Q P +  S   S  + +SP  +T  
Sbjct: 4104 VSEESSTSHSQPGSTHTTAFPD-----STTTSGLSQEPTTSHSSQGSTEATLSPGSTTAS 4158

Query: 357  TNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS--LQR 414
            +         S+P  +    +    +  G V  S      T        P S  S  LQ 
Sbjct: 4159 SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQE 4218

Query: 415  SSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFS 461
             S+     P  + T+ S  ++ A  V  +++  S  S TP    HFS
Sbjct: 4219 ESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTP--TTHFS 4263



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 58/287 (20%), Positives = 110/287 (38%), Gaps = 21/287 (7%)

Query: 188  RREVMQATATSGFASGKSTSGDKPVSHSCTTPS--TSSASGLNPTSAPPTSASAVPVSPV 245
            R  +  A++TS    G+ST+     + + TTPS  +++ + +  ++    S  + P +  
Sbjct: 2200 RTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 2259

Query: 246  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 305
            P S       + + +    P    T   ++++   S   E  T+ ++  S +       T
Sbjct: 2260 PASSTTSGHSEKSTIFHSSPDASGTTP-SSAHSTTSGRGESTTSRISPGSTEITTLPGST 2318

Query: 306  AGPSAFNI-TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST--PQTNTVPI 362
              P      T+  S     +T   P++ + + +  ++++ RS      ST  P + T P 
Sbjct: 2319 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 2378

Query: 363  KPLISTPPVSSQP-KVSTPVVKQGPVSQSATQQPVTADKQQGH-------EPVSPRSLQR 414
                ST   SS P    T V  + P +    ++P T   +          E  +   L  
Sbjct: 2379 LSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTE 2438

Query: 415  SSSQRSPSPGPNHTSNSSNASNA------TVVPQNSSARSTCSLTPA 455
             S+    SP    T   +  + A      T  P +S +  T +L+PA
Sbjct: 2439 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-TLSPA 2484



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 63/286 (22%), Positives = 110/286 (38%), Gaps = 27/286 (9%)

Query: 194  ATATSGFASGKSTSGDKPVS-HSCTTPSTSSASGLNPTS-APPTSASAVPVSPVPQSPIP 251
            +T +SG +   +TS  +P S H+   P +++  G++  S A  +S  +   +  P S   
Sbjct: 1709 STTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTA 1768

Query: 252  PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT-AGPSA 310
              L   +      P    T  L     D +  + +L A+    S     H  L+ AG + 
Sbjct: 1769 SSLGPESTTFHSSPGSTETTLLP----DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT 1824

Query: 311  FNITSLISQAAQLSTQAQPS---------NQSPMSLTSDASSPRSYVSPRIST----PQT 357
                S   Q+   S    P+           S  S  S +S+P ++ S   +T     ++
Sbjct: 1825 RQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEES 1884

Query: 358  NTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 417
             TV   P ++T    S  + +T     G V +S          Q  H P S  +  RS  
Sbjct: 1885 TTVHSSP-VATATTPSPARSTT----SGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE 1939

Query: 418  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSEN 463
             R+      HT +S  ++ + +V + +S  S+   T     HF ++
Sbjct: 1940 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGST--ATTHFPDS 1983



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 64/286 (22%), Positives = 115/286 (40%), Gaps = 27/286 (9%)

Query: 194  ATATSGFASGKSTSGDKPVS-HSCTTPSTSSASGLNPTS-APPTSASAVPVSPVPQSPIP 251
            +T +SG +   +TS  +P S H+   PS+++  G++  S A  +S  +   +  P S   
Sbjct: 4349 STTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTA 4408

Query: 252  PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT-AGPSA 310
              L   +      P    T  L     D +  + +L A+    S     H  L+ AG + 
Sbjct: 4409 SSLGPESTTFHSSPGSTETTLLP----DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT 4464

Query: 311  FNITSLISQA---AQLSTQAQPSNQSPM------SLTSDASSPRSYVSPRIST----PQT 357
                S   Q+   ++ +T A P+  S        S  S +S+P ++ S   +T     ++
Sbjct: 4465 RQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEES 4524

Query: 358  NTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 417
             TV   P ++T    S  + +T     G V +S T        Q  H P S  +  R   
Sbjct: 4525 TTVHSSP-VATATTPSPARSTT----SGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEE 4579

Query: 418  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSEN 463
              +      HT +S+ ++ + +V + +S  S+   T     HF ++
Sbjct: 4580 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST--ATTHFPDS 4623



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 53/263 (20%), Positives = 102/263 (38%), Gaps = 24/263 (9%)

Query: 188  RREVMQATATSGFASGKSTSGDKPVSHSCTTPS--TSSASGLNPTSAPPTSASAVPVSPV 245
            R  +  A++TS    G+ST+     + + TTPS  +++ + +  ++    S  + P +  
Sbjct: 2674 RTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 2733

Query: 246  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 305
            P S       + + +    P    T   ++++   S   E  T+ ++  S +       T
Sbjct: 2734 PASSTTSGHSEKSTIFHSSPDASGTTP-SSAHSTTSGRGESTTSRISPGSTEITTLPGST 2792

Query: 306  AGPSAFNI-TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKP 364
              P      T+  S     +T   P++ + + +  ++++ RS      ST       + P
Sbjct: 2793 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHST-------VSP 2845

Query: 365  LISTPPVSSQPKVSTPVVKQGPVSQSATQQP-VTADKQQGHEPVSPRSLQRSSSQRSPSP 423
              +T P  S+   ST V    P S   T  P  T    +G EP +  S           P
Sbjct: 2846 ASTTTPGLSEE--STTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHS----------RP 2893

Query: 424  GPNHTSNSSNASNATVVPQNSSA 446
               HT+  +  S  + + + S+A
Sbjct: 2894 ASTHTTLFTEDSTTSGLTEESTA 2916



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 63/286 (22%), Positives = 114/286 (39%), Gaps = 27/286 (9%)

Query: 194  ATATSGFASGKSTSGDKPVS-HSCTTPSTSSASGLNPTS-APPTSASAVPVSPVPQSPIP 251
            +T +SG +   +TS  +P S H+   P +++  G++  S A  +S  +   +  P S   
Sbjct: 3266 STTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTA 3325

Query: 252  PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT-AGPSA 310
              L   +      P    T  L     D +  + +L A+    S     H  L+ AG + 
Sbjct: 3326 SSLGPESTTFHSGPGSTETTLLP----DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT 3381

Query: 311  FNITSLISQA---AQLSTQAQPSNQSPM------SLTSDASSPRSYVSPRIST----PQT 357
                S   Q+   ++ +T A P+  S        S  S +S+P ++ S   +T     ++
Sbjct: 3382 RQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEES 3441

Query: 358  NTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 417
             TV   P ++T    S  + +T     G V +S T        Q  H P S  +  R   
Sbjct: 3442 TTVHSSP-VATATTPSPARSTT----SGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 3496

Query: 418  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSEN 463
              +      HT +S+ ++ + +V + +S  S+   T     HF ++
Sbjct: 3497 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST--ATTHFPDS 3540



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 57/287 (19%), Positives = 108/287 (37%), Gaps = 21/287 (7%)

Query: 188  RREVMQATATSGFASGKSTSGDKPVSHSCTTPS--TSSASGLNPTSAPPTSASAVPVSPV 245
            R  +  A++TS    G+ST+     + + TTPS  +++ + +  ++    S  + P +  
Sbjct: 3757 RTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 3816

Query: 246  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 305
            P S       + + +    P    T   ++++   S   E  T+ ++  S +       T
Sbjct: 3817 PASSTTSGHSEKSTIFHSSPDASGTTP-SSAHSTTSGRGESTTSRISPGSTEITTLPGST 3875

Query: 306  AGPSAFNI-TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST--PQTNTVPI 362
              P      T+  S     +T   P++ + + +  ++++ RS      ST  P + T P 
Sbjct: 3876 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 3935

Query: 363  KPLISTPPVSSQP-KVSTPVVKQGPVSQSATQQPVTADKQQGH-------EPVSPRSLQR 414
                ST   SS P    T V  +   +    ++P T   +          E  +   L  
Sbjct: 3936 LSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTE 3995

Query: 415  SSSQRSPSPGPNHTSNSSNASNA------TVVPQNSSARSTCSLTPA 455
             S+    SP    T   +  + A      T  P +S +  T  L+PA
Sbjct: 3996 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-KLSPA 4041



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 60/300 (20%), Positives = 110/300 (36%), Gaps = 23/300 (7%)

Query: 195 TATSGFASGKSTSGDKP-VSHSCTTPSTSSASGLNPTSAPPTSASAVPVSP----VPQSP 249
           T +SG +   +TS  +P  +H+   P +++  G++  S   T++ ++P S      P + 
Sbjct: 299 TTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQES---TASHSIPGSTDTTLSPGTT 355

Query: 250 IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 309
            P  L   +      P    T +L     D +  + +L A+    S     H  L+   S
Sbjct: 356 TPSSLGPESTTFHSSPGYTKTTRLP----DNTTTSGLLEASTPVHSSTGSPHTTLSPSSS 411

Query: 310 AFNI---TSLISQAAQLSTQAQPSNQSPMSL---TSDASSPRSYVSPRISTPQT---NTV 360
             +    T+  S  +   T   PS  +   +   T+  SSP S  +   S   T   ++ 
Sbjct: 412 TTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSE 471

Query: 361 PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRS 420
              P+ S+P  ++           G V +S          Q  H P S  +   S    +
Sbjct: 472 ESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESAT 531

Query: 421 PSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQA 480
                 HT +S+ ++ A +   ++S  S+   T       S  +    +   A H+   A
Sbjct: 532 FHGSTTHTKSSTPSTTAALA--HTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDA 589



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 62/282 (21%), Positives = 104/282 (36%), Gaps = 39/282 (13%)

Query: 194 ATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPL 253
           +TAT  F    + SG    S    T S S       T  P  SA++V V     SPI   
Sbjct: 205 STATKHFLDSSTNSGHSEES----TVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSA 260

Query: 254 LQDPNLLRQLLPALQATLQLNNSNVDI--SKINEVLTAAVTQASLQSIIHKFLTA----G 307
             +   L    P    T  L+  +     S  +   T +  + +   +  K  T+    G
Sbjct: 261 SMETTAL----PGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPG 316

Query: 308 PS---AFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKP 364
           P+   AF  ++ +   +Q ST +           S   S  + +SP  +TP +       
Sbjct: 317 PTHTIAFPDSTTMPGVSQESTASH----------SIPGSTDTTLSPGTTTPSSLGPESTT 366

Query: 365 LISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPS-- 422
             S+P  +   ++       G +  S    PV +     H  +SP S   ++ +  P+  
Sbjct: 367 FHSSPGYTKTTRLPDNTTTSGLLEAST---PVHSSTGSPHTTLSPSS--STTHEGEPTTF 421

Query: 423 ---PGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFS 461
              P    TS + + + +  V  +++  S+ S TP    HFS
Sbjct: 422 QSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTP--TTHFS 461



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 56/283 (19%), Positives = 99/283 (34%), Gaps = 21/283 (7%)

Query: 194 ATATSGFASGKSTSGDKPVSHSCT-TPSTSSASGLNPTSAPPTSA-SAVPVSPVPQSPIP 251
           +T   G +   +T    P S   T  P++ ++SG++  S    S   +   +  P S   
Sbjct: 626 STTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 685

Query: 252 PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAF 311
           P L   +      P    T     S    S   E  T      S ++      T  P   
Sbjct: 686 PGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTET------TLLPDNT 739

Query: 312 NITSLI--SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVS------PRISTPQTNTVPIK 363
             + L+  S     ST++  +  SP   T+      ++ S       R + P T +  ++
Sbjct: 740 TASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVE 799

Query: 364 PLIST---PPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRS 420
           P  ++   P       +S      G V +S T        Q  H P S  +  R     +
Sbjct: 800 PSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 859

Query: 421 PSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSEN 463
                 HT +S+ ++ + +V + +S  S+   T     HF ++
Sbjct: 860 SHSSTTHTISSAPSTTSALVEEPTSYHSSPGST--ATTHFPDS 900



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 52/263 (19%), Positives = 100/263 (38%), Gaps = 24/263 (9%)

Query: 188  RREVMQATATSGFASGKSTSGDKPVSHSCTTPS--TSSASGLNPTSAPPTSASAVPVSPV 245
            R  +  A++TS    G+ST+     + + TTPS  +++ + +  ++    S  + P +  
Sbjct: 1117 RTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 1176

Query: 246  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 305
            P S       + + +    P    T   ++++   S   E  T+ ++  S +       T
Sbjct: 1177 PASSTTSGHSEKSTIFHSSPDASGTTP-SSAHSTTSGRGESTTSRISPGSTEITTLPGST 1235

Query: 306  AGPSAFNI-TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKP 364
              P      T+  S     +T   P++ + + +  ++++ RS      ST       + P
Sbjct: 1236 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHST-------VSP 1288

Query: 365  LISTPPVSSQPKVSTPVVKQGPVSQSATQQP-VTADKQQGHEPVSPRSLQRSSSQRSPSP 423
              +T P  S+   ST V      S   T  P  T     G EP +  S           P
Sbjct: 1289 ASTTTPGLSEE--STTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHS----------RP 1336

Query: 424  GPNHTSNSSNASNATVVPQNSSA 446
               HT+  +  S  + + + S+A
Sbjct: 1337 ASTHTTLFTEDSTTSGLTEESTA 1359


>gi|219802034 nuclear factor related to kappaB binding protein
           isoform 1 [Homo sapiens]
          Length = 1299

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 61/255 (23%), Positives = 107/255 (41%), Gaps = 36/255 (14%)

Query: 204 KSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS----------AVPVSPVPQSPIPPL 253
           KS+S +  +    + PS  S   L+ +S PPT  +          A+P+SP P S +   
Sbjct: 687 KSSSKESSIKVLSSGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPAIPISPPPVSAVNK- 745

Query: 254 LQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNI 313
              P+ + +  PA  ++  L  S+  +  +  +L+ A +Q +  S     + +   +  +
Sbjct: 746 -SGPSTVSE--PAKSSSGVLLVSSPTMPHLGTMLSPASSQTAPSSQAAARVVSHSGSAGL 802

Query: 314 TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTP----QTNTVPIKPLISTP 369
            S +   AQ S  A P      + T     P+    P+I  P    QT  VP + +++T 
Sbjct: 803 -SQVRVVAQPSLPAVPQQSGGPAQT----LPQMPAGPQIRVPATATQTKVVP-QTVMATV 856

Query: 370 PVSSQPKVSTPVVKQGP--VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 427
           PV +Q   +T V + GP     + T  P TA         SP S   +SS  + +P  + 
Sbjct: 857 PVKAQTTAAT-VQRPGPGQTGLTVTSLPATA---------SPVSKPATSSPGTSAPSAST 906

Query: 428 TSNSSNASNATVVPQ 442
            +   N +   ++ Q
Sbjct: 907 AAVIQNVTGQNIIKQ 921



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 47/137 (34%), Positives = 63/137 (45%), Gaps = 7/137 (5%)

Query: 308 PSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLIS 367
           PS    +S  S    LS+   PS QS MSL SD+S P + V+P   TP T  +P  P IS
Sbjct: 683 PSKVKSSSKESSIKVLSSG--PSEQSQMSL-SDSSMPPTPVTP--VTPTTPALPAIP-IS 736

Query: 368 TPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 427
            PPVS+  K     V +   S S      +         +SP S Q + S ++ +   +H
Sbjct: 737 PPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHLGTMLSPASSQTAPSSQAAARVVSH 796

Query: 428 TSNSSNASNATVVPQNS 444
            S S+  S   VV Q S
Sbjct: 797 -SGSAGLSQVRVVAQPS 812



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 67/301 (22%), Positives = 119/301 (39%), Gaps = 50/301 (16%)

Query: 197  TSGFASGKSTSGDKPVS----HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPP 252
            T G  +GK  S    V+    H+  +P+   AS  +  S+ PT  + V V+P     + P
Sbjct: 997  TGGNTTGKGISATLHVTSNPVHAADSPA--KASSASAPSSTPTGTTVVKVTP----DLKP 1050

Query: 253  LLQDPNLLRQLLPALQATL--QLNNSNVDIS-------------------KINEVLTAAV 291
                 +  R L+PAL  ++  Q   S V  S                   K  + +T A 
Sbjct: 1051 TEASSSAFR-LMPALGVSVADQKGKSTVASSEAKPAATIRIVQGLGVMPPKAGQTITVAT 1109

Query: 292  TQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRS--YVS 349
                  S+     T   SA ++ S+ +  ++    A  +  +P+S+++ A + R     +
Sbjct: 1110 HAKQGASVASGSGTVHTSAVSLPSMNAAVSKTVAVASGAASTPISISTGAPTVRQVPVST 1169

Query: 350  PRISTPQTNTVPIK---PL-ISTPPVSSQPKVSTPVVKQGPVSQSA--------TQQPVT 397
              +ST Q   +P +   PL + + P+  +  V+ P++K    +  +        T  P  
Sbjct: 1170 TVVSTSQAGKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAG 1229

Query: 398  ADKQQGHEPVS---PRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
                 G++PVS    + LQ+   Q   +     T  +S+    T    +S A ST  +T 
Sbjct: 1230 TKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGT-ASGSSKAVSTVVVTT 1288

Query: 455  A 455
            A
Sbjct: 1289 A 1289


>gi|23346420 nuclear factor related to kappaB binding protein
           isoform 2 [Homo sapiens]
          Length = 1324

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 61/255 (23%), Positives = 107/255 (41%), Gaps = 36/255 (14%)

Query: 204 KSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS----------AVPVSPVPQSPIPPL 253
           KS+S +  +    + PS  S   L+ +S PPT  +          A+P+SP P S +   
Sbjct: 712 KSSSKESSIKVLSSGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPAIPISPPPVSAVNK- 770

Query: 254 LQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNI 313
              P+ + +  PA  ++  L  S+  +  +  +L+ A +Q +  S     + +   +  +
Sbjct: 771 -SGPSTVSE--PAKSSSGVLLVSSPTMPHLGTMLSPASSQTAPSSQAAARVVSHSGSAGL 827

Query: 314 TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTP----QTNTVPIKPLISTP 369
            S +   AQ S  A P      + T     P+    P+I  P    QT  VP + +++T 
Sbjct: 828 -SQVRVVAQPSLPAVPQQSGGPAQT----LPQMPAGPQIRVPATATQTKVVP-QTVMATV 881

Query: 370 PVSSQPKVSTPVVKQGP--VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 427
           PV +Q   +T V + GP     + T  P TA         SP S   +SS  + +P  + 
Sbjct: 882 PVKAQTTAAT-VQRPGPGQTGLTVTSLPATA---------SPVSKPATSSPGTSAPSAST 931

Query: 428 TSNSSNASNATVVPQ 442
            +   N +   ++ Q
Sbjct: 932 AAVIQNVTGQNIIKQ 946



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 47/137 (34%), Positives = 63/137 (45%), Gaps = 7/137 (5%)

Query: 308 PSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLIS 367
           PS    +S  S    LS+   PS QS MSL SD+S P + V+P   TP T  +P  P IS
Sbjct: 708 PSKVKSSSKESSIKVLSSG--PSEQSQMSL-SDSSMPPTPVTP--VTPTTPALPAIP-IS 761

Query: 368 TPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 427
            PPVS+  K     V +   S S      +         +SP S Q + S ++ +   +H
Sbjct: 762 PPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHLGTMLSPASSQTAPSSQAAARVVSH 821

Query: 428 TSNSSNASNATVVPQNS 444
            S S+  S   VV Q S
Sbjct: 822 -SGSAGLSQVRVVAQPS 837



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 67/301 (22%), Positives = 119/301 (39%), Gaps = 50/301 (16%)

Query: 197  TSGFASGKSTSGDKPVS----HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPP 252
            T G  +GK  S    V+    H+  +P+   AS  +  S+ PT  + V V+P     + P
Sbjct: 1022 TGGNTTGKGISATLHVTSNPVHAADSPA--KASSASAPSSTPTGTTVVKVTP----DLKP 1075

Query: 253  LLQDPNLLRQLLPALQATL--QLNNSNVDIS-------------------KINEVLTAAV 291
                 +  R L+PAL  ++  Q   S V  S                   K  + +T A 
Sbjct: 1076 TEASSSAFR-LMPALGVSVADQKGKSTVASSEAKPAATIRIVQGLGVMPPKAGQTITVAT 1134

Query: 292  TQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRS--YVS 349
                  S+     T   SA ++ S+ +  ++    A  +  +P+S+++ A + R     +
Sbjct: 1135 HAKQGASVASGSGTVHTSAVSLPSMNAAVSKTVAVASGAASTPISISTGAPTVRQVPVST 1194

Query: 350  PRISTPQTNTVPIK---PL-ISTPPVSSQPKVSTPVVKQGPVSQSA--------TQQPVT 397
              +ST Q   +P +   PL + + P+  +  V+ P++K    +  +        T  P  
Sbjct: 1195 TVVSTSQAGKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAG 1254

Query: 398  ADKQQGHEPVS---PRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
                 G++PVS    + LQ+   Q   +     T  +S+    T    +S A ST  +T 
Sbjct: 1255 TKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGT-ASGSSKAVSTVVVTT 1313

Query: 455  A 455
            A
Sbjct: 1314 A 1314


>gi|183396804 Regulation of nuclear pre-mRNA domain containing 2
           [Homo sapiens]
          Length = 1461

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 59/260 (22%), Positives = 108/260 (41%), Gaps = 24/260 (9%)

Query: 209 DKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQ 268
           +KP   S  + S  +     PT     ++S  PV PV  +  PPL +  N      PAL 
Sbjct: 390 EKPAEKSAVSTSVPT----KPTENISKASSCTPV-PVTMTATPPLPKPVNTSLSPSPALA 444

Query: 269 ATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 328
                N +NVD++KI+ +L +++T     + +       P      S ++   +    A 
Sbjct: 445 LP---NLANVDLAKISSIL-SSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPAT 500

Query: 329 PSNQSPMS--LTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGP 386
            ++ +P++  L+    +P S +S  +S  QT + P    +S+     Q     PV    P
Sbjct: 501 TTSHNPLANILSKVEITPESILS-ALSKTQTQSAPALQGLSS---LLQSVTGNPV----P 552

Query: 387 VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP-----SPGPNHTSNSSNASNATVVP 441
            S++A+Q    +        +  R+L  S+    P     SP  + +  SS +++   + 
Sbjct: 553 ASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIG 612

Query: 442 QNSSARSTCSLTPALAAHFS 461
           Q+    ST    P+ +  F+
Sbjct: 613 QSPGLPSTTFKLPSNSLGFT 632


>gi|238624188 diffuse panbronchiolitis critical region 1 protein
           [Homo sapiens]
          Length = 1393

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 91/457 (19%), Positives = 157/457 (34%), Gaps = 68/457 (14%)

Query: 54  PPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSH 113
           PP          + ++ ++T HSK  +  T   +  D  +S      + NH A  +S  +
Sbjct: 71  PPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSS------TDNHEAPPTSEEN 124

Query: 114 SSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYY-------YNCR-------TEVSQWEK 159
           SSN   +P   +    D AD  + H  S+GKK+         NCR       T   + +K
Sbjct: 125 SSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDK 184

Query: 160 PKEWLERE----QRQKEANKMAVNSF---------PKDRDYRREVMQATATSGFASGKST 206
               LE+      +   ++     SF          K   +  ++  A+ T+   +G   
Sbjct: 185 TGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPE 244

Query: 207 SGDKPVSHSCTTPS-------------TSSASGLNPTSAPPTSASAVPV----SPVPQSP 249
             +K      T  S             T SA+ L  + A PT           +P P  P
Sbjct: 245 ESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEP 304

Query: 250 IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKI------NEVLTA--AVTQASLQSIIH 301
                +  N    L PA     +   +N + +        N  +TA    T    +   H
Sbjct: 305 TENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEH 364

Query: 302 KFLTAG----PSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQT 357
              TA     PS    T    + A  +T   P+  +     +  ++ ++  S   ST   
Sbjct: 365 GERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHG 424

Query: 358 NTVPIKPLISTP----PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQ 413
              P+    +TP    P  ++ + +       P   +  ++  TA+++    PV P   +
Sbjct: 425 ERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRE-TTANEKTTLSPVEPTENR 483

Query: 414 RSSSQRSPSPGP-NHTSNSSNASNATVVPQNSSARST 449
            +++    +P P   T N      A     +SSA  T
Sbjct: 484 ETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPT 520



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 77/429 (17%), Positives = 144/429 (33%), Gaps = 43/429 (10%)

Query: 32  SKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERDG 91
           S + P+    R         P+ P +   R+    +K + S+  S     H  R    + 
Sbjct: 376 SPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTE---HGERTPLANE 432

Query: 92  GTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNCR 151
            T+ SP E + N     ++N +++     P++  +   +     S    +  ++   N +
Sbjct: 433 NTTPSPAEPTENRE--RTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEK 490

Query: 152 TEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGKSTSGDKP 211
           T  S    P E  E  QR   AN+   +S  +  ++      A   +  +  + T   + 
Sbjct: 491 TTPS----PAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRER 546

Query: 212 VSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATL 271
            ++  TTPS           A PT       +P+      P L +P    Q  P   A  
Sbjct: 547 TANEKTTPS----------PAEPTENG--DRTPLANEKTTPSLAEPTENGQRTPF--ANE 592

Query: 272 QLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSN 331
           +  +S+ + ++  E    A    +            PS    T    + A  +T   PS 
Sbjct: 593 KTTSSSAEPTEHEERTPLANENTT------------PSPAEPTENRERTANENT--TPSP 638

Query: 332 QSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSA 391
             P       ++ ++ + P   T        +   S+P   ++    TP   +   S SA
Sbjct: 639 AGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSA 698

Query: 392 T-----QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGP-NHTSNSSNASNATVVPQNSS 445
                 ++   A++     P  P   +  ++    +P P   T N    +N    P  + 
Sbjct: 699 EPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQ 758

Query: 446 ARSTCSLTP 454
                  TP
Sbjct: 759 PTENGDRTP 767


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 64/261 (24%), Positives = 101/261 (38%), Gaps = 35/261 (13%)

Query: 211 PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 270
           P++HS    S  S  G+           A+  S +PQ P        N++ Q  PA    
Sbjct: 708 PMNHSVQMNSMGSVPGM-----------AISPSRMPQPPNMMGAHTNNMMAQA-PAQSQF 755

Query: 271 LQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-QAAQLSTQAQP 329
           L  N         +  ++  + Q   Q+ + +    G +  N  +++  QA+QL     P
Sbjct: 756 LPQNQ----FPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLP--CPP 809

Query: 330 SNQSPMSLTSD-ASSPRSYVSPRISTP--QTNTVPIKPLISTPPVSSQPKVSTPV----- 381
             QSP+  T   AS+     S + +TP   T   P  P   + PVSS  +  TP      
Sbjct: 810 VTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVP 869

Query: 382 ----VKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP----SPGPNHTSNSSN 433
                +  P  Q+A Q  VT   Q   +P S  + Q S  Q +P     PG   +  +++
Sbjct: 870 SATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAAS 929

Query: 434 ASNATVVPQNSSARSTCSLTP 454
             N    P + ++  T S  P
Sbjct: 930 IDNRVPTPSSVASAETNSQQP 950



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 45/219 (20%), Positives = 75/219 (34%), Gaps = 20/219 (9%)

Query: 208 GDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL 267
           G  P     +      A+  NP +     AS +P  PV QSP+ P    P      +P+L
Sbjct: 773 GQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPT-PPPASTAAGMPSL 831

Query: 268 QATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAG--PSAFNITSLISQAAQLST 325
           Q T     +    +   +  T   +     +      T G  PSA    S  +  A    
Sbjct: 832 QHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTP-----TPGSVPSATQTQSTPTVQAAAQA 886

Query: 326 QAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQG 385
           Q  P  Q+P+              P ++TPQ++     P+ + PP +   + +  +  + 
Sbjct: 887 QVTPQPQTPVQ------------PPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV 934

Query: 386 PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG 424
           P   S       + +     PV     +  +    P PG
Sbjct: 935 PTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPG 973



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 53/238 (22%), Positives = 92/238 (38%), Gaps = 43/238 (18%)

Query: 246  PQSP--IPPLLQDPNLLRQLLPALQATL-QLNNSNVDISKINEVLTAAVTQASLQSIIHK 302
            PQ P   PP +Q    ++Q LP   +++ Q+      + ++ +    A +  ++Q  + +
Sbjct: 2196 PQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQ 2255

Query: 303  FLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYV-SPRISTPQTNTVP 361
                      I        Q+ +  QP+  SP           S++   +I+T  +N V 
Sbjct: 2256 ---------RILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVR 2306

Query: 362  IKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
                + +P   SQP  S+P  +  P              Q     VSP++        SP
Sbjct: 2307 SPAPVQSPRPQSQPPHSSPSPRIQP--------------QPSPHHVSPQT-------GSP 2345

Query: 422  SPGPNHTSNSS-------NASNATVVPQ-NSSARSTCSLTPALAAHFS-ENLIKHVQG 470
             PG   T  SS       N   + ++PQ N+ +RS  S   +L    + + L K V+G
Sbjct: 2346 HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEG 2403



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 2/67 (2%)

Query: 331  NQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQS 390
            N    SL S  S+P    + + STPQT   P +P  S  PVS  P     V +  P +  
Sbjct: 1838 NVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPS--PVSMSPAGFPSVARTQPPTTV 1895

Query: 391  ATQQPVT 397
            +T +P +
Sbjct: 1896 STGKPTS 1902


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 64/261 (24%), Positives = 101/261 (38%), Gaps = 35/261 (13%)

Query: 211 PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 270
           P++HS    S  S  G+           A+  S +PQ P        N++ Q  PA    
Sbjct: 746 PMNHSVQMNSMGSVPGM-----------AISPSRMPQPPNMMGAHTNNMMAQA-PAQSQF 793

Query: 271 LQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-QAAQLSTQAQP 329
           L  N         +  ++  + Q   Q+ + +    G +  N  +++  QA+QL     P
Sbjct: 794 LPQNQ----FPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLP--CPP 847

Query: 330 SNQSPMSLTSD-ASSPRSYVSPRISTP--QTNTVPIKPLISTPPVSSQPKVSTPV----- 381
             QSP+  T   AS+     S + +TP   T   P  P   + PVSS  +  TP      
Sbjct: 848 VTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVP 907

Query: 382 ----VKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP----SPGPNHTSNSSN 433
                +  P  Q+A Q  VT   Q   +P S  + Q S  Q +P     PG   +  +++
Sbjct: 908 SATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAAS 967

Query: 434 ASNATVVPQNSSARSTCSLTP 454
             N    P + ++  T S  P
Sbjct: 968 IDNRVPTPSSVASAETNSQQP 988



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 45/219 (20%), Positives = 75/219 (34%), Gaps = 20/219 (9%)

Query: 208  GDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL 267
            G  P     +      A+  NP +     AS +P  PV QSP+ P    P      +P+L
Sbjct: 811  GQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPT-PPPASTAAGMPSL 869

Query: 268  QATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAG--PSAFNITSLISQAAQLST 325
            Q T     +    +   +  T   +     +      T G  PSA    S  +  A    
Sbjct: 870  QHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTP-----TPGSVPSATQTQSTPTVQAAAQA 924

Query: 326  QAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQG 385
            Q  P  Q+P+              P ++TPQ++     P+ + PP +   + +  +  + 
Sbjct: 925  QVTPQPQTPVQ------------PPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV 972

Query: 386  PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG 424
            P   S       + +     PV     +  +    P PG
Sbjct: 973  PTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPG 1011



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 53/238 (22%), Positives = 92/238 (38%), Gaps = 43/238 (18%)

Query: 246  PQSP--IPPLLQDPNLLRQLLPALQATL-QLNNSNVDISKINEVLTAAVTQASLQSIIHK 302
            PQ P   PP +Q    ++Q LP   +++ Q+      + ++ +    A +  ++Q  + +
Sbjct: 2234 PQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQ 2293

Query: 303  FLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYV-SPRISTPQTNTVP 361
                      I        Q+ +  QP+  SP           S++   +I+T  +N V 
Sbjct: 2294 ---------RILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVR 2344

Query: 362  IKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
                + +P   SQP  S+P  +  P              Q     VSP++        SP
Sbjct: 2345 SPAPVQSPRPQSQPPHSSPSPRIQP--------------QPSPHHVSPQT-------GSP 2383

Query: 422  SPGPNHTSNSS-------NASNATVVPQ-NSSARSTCSLTPALAAHFS-ENLIKHVQG 470
             PG   T  SS       N   + ++PQ N+ +RS  S   +L    + + L K V+G
Sbjct: 2384 HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEG 2441



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 2/67 (2%)

Query: 331  NQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQS 390
            N    SL S  S+P    + + STPQT   P +P  S  PVS  P     V +  P +  
Sbjct: 1876 NVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPS--PVSMSPAGFPSVARTQPPTTV 1933

Query: 391  ATQQPVT 397
            +T +P +
Sbjct: 1934 STGKPTS 1940


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 10/111 (9%)

Query: 312 NITSLISQAAQLSTQAQPSNQSPMSLTS-DASSPRSYVSPRISTPQTNTVPIKPLISTPP 370
           +I +L  +  +L +   P +  P  LT  +   P S VSP + TP  +  P KP   + P
Sbjct: 126 SIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSP 185

Query: 371 VSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
              +P  S PV       +S    PV + + Q   PVSP S++ + S   P
Sbjct: 186 ---EPPKSVPVC------ESQKLAPVPSPEPQKPAPVSPESVKATLSNPKP 227



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 28/111 (25%), Positives = 39/111 (35%), Gaps = 12/111 (10%)

Query: 329 PSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQG 385
           P  + P    S  S    P     P  S P  ++ P KP    P VS  P    P V  G
Sbjct: 298 PEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPG 357

Query: 386 P------VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQ---RSPSPGPNH 427
           P      VS ++ +    +       P SP S +    +    +P+  P H
Sbjct: 358 PWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEH 408


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 75/299 (25%), Positives = 109/299 (36%), Gaps = 63/299 (21%)

Query: 207  SGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVP-----VSPVPQSPIPPLLQDPNLLR 261
            S   P+S   T P+ +SA    P SAP T +++ P     V+P P +P+ P    P    
Sbjct: 1436 SSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTP-PLAPVVPAAPGP---- 1490

Query: 262  QLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAA 321
                    +L  + ++   S +   L  A + +S Q+  H  L A P++ ++  L S  A
Sbjct: 1491 -------PSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLA-PTSSHVPGLNSTVA 1542

Query: 322  QL--------STQAQPSNQSPMSLTSDAS--SPRSYVSPRISTP-------QTNTV---P 361
                      S  A P   +P    + AS  +P S  S  ++TP       QT  +   P
Sbjct: 1543 PACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSP 1602

Query: 362  IKPLISTPPVSSQPKVS-------TPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQR 414
              PL   P ++  P  +       TPV    P S   T     +        ++P S Q 
Sbjct: 1603 APPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQT 1662

Query: 415  SSSQRSPSPGPNHTSN------------------SSNASNATVVPQNSSARSTCSLTPA 455
                  PSP P+  S                   S   S  T  PQ      T SLTPA
Sbjct: 1663 MLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPA 1721



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 66/244 (27%), Positives = 94/244 (38%), Gaps = 30/244 (12%)

Query: 211  PVSHSCTTPSTSSASGLNPTSAP-----PTSASAVPVSPVPQS-PIPPLLQDPNLLRQLL 264
            PV    +TP TS AS  +P  AP     P+S   +  +PVP   P P   Q   L   L 
Sbjct: 1630 PVMAPSSTPGTSLASA-SPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALA 1688

Query: 265  PAL-----QATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF-LTAGPSAFNITSLIS 318
            P L       TL L   N       + L+     + + +      L  GP      +L  
Sbjct: 1689 PTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSL 1748

Query: 319  QAAQLSTQAQPSNQSPM-SLT-SDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 376
              A     A P   +P  +LT + ASS  S ++P  ++ QT T+   P+ +  P ++Q  
Sbjct: 1749 APAPPLAPASPVGPAPAHTLTLAPASSSASLLAP--ASVQTLTLSPAPVPTLGPAAAQTL 1806

Query: 377  VSTPVVKQGPVSQS---------ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 427
               P   Q P SQ+         A   PVT   +       P +L    + RS  P P  
Sbjct: 1807 ALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTL----TLRSGPPSPPS 1862

Query: 428  TSNS 431
            T+ S
Sbjct: 1863 TATS 1866



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 38/283 (13%)

Query: 206  TSGDKPVSH-SCTTPSTSSA-SGLN---------PTSAPPTSASAVPVSPVPQ---SPIP 251
            T G  PVS    +TPST+ A +GL+         PT    T    + V   P+   +P+P
Sbjct: 1266 TPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVP 1325

Query: 252  PLLQDPNLLRQLLPA-LQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSA 310
            PL   P      LPA L     L    +    +        T   ++ ++    +  P  
Sbjct: 1326 PLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEV 1385

Query: 311  FNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPR---------SYVSPRISTPQTNTVP 361
                S  +  A   T + P +  P SL   ASSP          S VS  +S P ++++P
Sbjct: 1386 ----SASAPGAAPLTISSPLHV-PSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLP 1440

Query: 362  IKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 421
            I    + P  +S P ++ P+    P++ SA+   +         PV P      ++   P
Sbjct: 1441 ISVPTTLPAPASAP-LTIPI--SAPLTVSASGPALLTSVTPPLAPVVP------AAPGPP 1491

Query: 422  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSENL 464
            S  P+  S S++A    +    S + S     P L A  S ++
Sbjct: 1492 SLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHV 1534



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 50/254 (19%), Positives = 94/254 (37%), Gaps = 30/254 (11%)

Query: 211  PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 270
            P   S   P +S A    P   PP + +  P      +P  PLL  P       P++  +
Sbjct: 2485 PPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGP-------PSVPIS 2537

Query: 271  LQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI--SQAAQLSTQAQ 328
              + N  + +    E+   A+  AS +S+  +  +   S  +  SL+       ++ +  
Sbjct: 2538 ASVTNLPLGLRPEAELCAQAL--ASPESL--ELASVASSETSSLSLVPPKDLLPVAVEIL 2593

Query: 329  PSNQSPMSLTSDASS--------PRSYVSPRISTPQTNTVPIKP--------LISTPPVS 372
            P ++  +SLT  A S        P         + +  T+ + P        +  +  + 
Sbjct: 2594 PVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLE 2653

Query: 373  SQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 432
              P  ++    Q P+    T + +T  K     P  P+ L  ++   +PS   + TS+  
Sbjct: 2654 LPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELV-TAEVAAPSTSSSATSSPE 2712

Query: 433  NASNATVVPQNSSA 446
              S A    + +SA
Sbjct: 2713 GPSPARPPRRRTSA 2726


>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
          Length = 2245

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 67/265 (25%), Positives = 117/265 (44%), Gaps = 23/265 (8%)

Query: 186 DYRREVMQATATSGFASGKSTSGDK-PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSP 244
           D++   + +  T+  +    T+GD  P+S S +   TS+A+ +  +SAP    + +P+S 
Sbjct: 330 DFQNTFVVSVTTTVCSQPPRTAGDSSPMSISKSADLTSTATVV-ASSAPGVGKATIPIST 388

Query: 245 VPQSPIPPLLQDPNLLRQLLPALQ-ATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF 303
           +  +P    L +   L   LP+   +T  L N N  +++I+       T  +LQ   +  
Sbjct: 389 LSGNP----LDNGWTLSCSLPSSSVSTSDLKNIN-SLTRISSAGNTQTTWTTLQLAGNTI 443

Query: 304 --LTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSP---RSYVSPRISTPQTN 358
             L+  PS+  +T +++++    T +  S      +  + S P   +      ++ P   
Sbjct: 444 QPLSQTPSSA-VTPVLNESGTSPTTSNHSRYVATDINLNNSFPADGQPVEQVVVTLPSCP 502

Query: 359 TVPIKPLISTPPVSSQ-PKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 417
           ++P++PLI+ P V SQ PK   P+     V Q A  QPV      G    S  + Q    
Sbjct: 503 SLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQMA--QPV------GSAVNSAPTNQNVII 554

Query: 418 QRSPSPGPNHTSNSSNASNATVVPQ 442
            + PS  P  T   +  SN TV  Q
Sbjct: 555 LQPPSTTPCPTVMRAEVSNQTVGQQ 579



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 40/179 (22%), Positives = 77/179 (43%), Gaps = 15/179 (8%)

Query: 206 TSGDKPVSHSCTTPSTSSASGLNPT-SAPPTSASAVPVSPVPQS-PIPPLLQDPNLLRQL 263
           T G K + H    PS+ SAS    T S   ++     +S   Q   + P++       Q 
Sbjct: 627 TFGGKHLVHILPRPSSLSASNSTQTFSVTMSNQQPQTISLNGQLFALQPVMSSSGTTNQT 686

Query: 264 -LPALQATLQLN-NSNVDISKINEV--LTAAVTQASLQSIIHKFLTA---GPSAFNITSL 316
            +  +Q T   + N+NV ++    +  L  +++Q + QS +   ++      +A N  + 
Sbjct: 687 PMQIIQPTTSEDPNTNVALNTFGALASLNQSISQMAGQSCVQLSISQPANSQTAANSQTT 746

Query: 317 ISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQP 375
            +    L+T A P       +T+D+S+  +     +ST   NTV   P + +  ++ +P
Sbjct: 747 TANCVSLTTTAAPP------VTTDSSATLASTYNLVSTSSMNTVACLPNMKSKRLNKKP 799


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 89/401 (22%), Positives = 152/401 (37%), Gaps = 65/401 (16%)

Query: 84   HRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSAD--DWSEHISS 141
            +R R+R+   S S  EN      L S + H+S   +N      +  D+ +  D +  +  
Sbjct: 1162 YRKRQREARKSGSKTENF----PLISVSPHASGSLSNNGDGCASSNDNGEQVDHTASLPL 1217

Query: 142  SGKKYYYNCRTEVSQWEKP-KEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGF 200
                  YN  +E +    P K+    E+ + E    A  S  + R+  R   +A   S  
Sbjct: 1218 PTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQVRE--RSYQRALLLSDH 1275

Query: 201  ASGKSTSGDKPV-----SHSCTTPSTSS-------ASGL-----------NPTSAPPTSA 237
               K + G+ P      SH  ++PS+ S       A G            +P +  PT+ 
Sbjct: 1276 RKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTT 1335

Query: 238  SAVPVSPVPQSPI--PPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQAS 295
            +  P     Q+    PP +  P     ++PA QA  ++       +K +    + V+ + 
Sbjct: 1336 NECPSPDTSQNTCKSPPKMSKPGSPGSVIPA-QAHGKI------FTKPDPQWDSTVSASE 1388

Query: 296  LQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTP 355
             ++ +H            T L  +    + QA   N  P +   ++S   S   P  S P
Sbjct: 1389 AENGVHLK----------TELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLP--SVP 1436

Query: 356  QTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRS 415
                 P  P +  PP SS P   TP V+ G +S     Q + +     + P   +S Q  
Sbjct: 1437 TKLHCPPSPHLENPPKSSTP--HTP-VQHGYLSPKPPSQQLGSP----YRPHHSQSPQVG 1489

Query: 416  SSQRSPS-----PGPNHTSNSSNASNATVVPQNSSARSTCS 451
            + QR P         N  +N+  A++ T+  Q  S +S+ +
Sbjct: 1490 TPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSAT 1530


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 89/401 (22%), Positives = 152/401 (37%), Gaps = 65/401 (16%)

Query: 84   HRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSAD--DWSEHISS 141
            +R R+R+   S S  EN      L S + H+S   +N      +  D+ +  D +  +  
Sbjct: 1162 YRKRQREARKSGSKTENF----PLISVSPHASGSLSNNGDGCASSNDNGEQVDHTASLPL 1217

Query: 142  SGKKYYYNCRTEVSQWEKP-KEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGF 200
                  YN  +E +    P K+    E+ + E    A  S  + R+  R   +A   S  
Sbjct: 1218 PTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQVRE--RSYQRALLLSDH 1275

Query: 201  ASGKSTSGDKPV-----SHSCTTPSTSS-------ASGL-----------NPTSAPPTSA 237
               K + G+ P      SH  ++PS+ S       A G            +P +  PT+ 
Sbjct: 1276 RKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTT 1335

Query: 238  SAVPVSPVPQSPI--PPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQAS 295
            +  P     Q+    PP +  P     ++PA QA  ++       +K +    + V+ + 
Sbjct: 1336 NECPSPDTSQNTCKSPPKMSKPGSPGSVIPA-QAHGKI------FTKPDPQWDSTVSASE 1388

Query: 296  LQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTP 355
             ++ +H            T L  +    + QA   N  P +   ++S   S   P  S P
Sbjct: 1389 AENGVHLK----------TELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLP--SVP 1436

Query: 356  QTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRS 415
                 P  P +  PP SS P   TP V+ G +S     Q + +     + P   +S Q  
Sbjct: 1437 TKLHCPPSPHLENPPKSSTP--HTP-VQHGYLSPKPPSQQLGSP----YRPHHSQSPQVG 1489

Query: 416  SSQRSPS-----PGPNHTSNSSNASNATVVPQNSSARSTCS 451
            + QR P         N  +N+  A++ T+  Q  S +S+ +
Sbjct: 1490 TPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSAT 1530


>gi|148612879 polyhomeotic like 3 [Homo sapiens]
          Length = 995

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 73/264 (27%), Positives = 104/264 (39%), Gaps = 47/264 (17%)

Query: 193 QATATSGFASGKSTS------GDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP 246
           + T TS   S +  S      G+ P   S +T  T ++S ++   AP + +   P S + 
Sbjct: 261 KTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSS-IHQLIAPASYSPIQPHSLIK 319

Query: 247 QSPIPPLLQDPN-------LLRQLLPALQATLQLNNSNVD-------ISKINEVLTAAVT 292
              IP L   P+       +L+Q    +Q  + L NS  D       I   N  L  A +
Sbjct: 320 HQQIP-LHSPPSKVSHHQLILQQQQQQIQP-ITLQNSTQDPPPSQHCIPLQNHGLPPAPS 377

Query: 293 QASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPS-----NQSPMSLTSDAS--SPR 345
            A  Q      + + PS   ++   SQ+AQ S    P      +QSP  +    +   P 
Sbjct: 378 NAQSQHCSP--IQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPH 435

Query: 346 SYVS------PRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTAD 399
             VS      P +     N V     ++ P  S  P  ++PVV  GPV QSA   P    
Sbjct: 436 PLVSSALQPGPNLQQSTANQVQATAQLNLP--SHLPLPASPVVHIGPVQQSALVSP---- 489

Query: 400 KQQGHEPVSPRSLQRSSSQRSPSP 423
              G + VSP   Q SS Q SP P
Sbjct: 490 ---GQQIVSPSHQQYSSLQSSPIP 510


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 46/216 (21%), Positives = 78/216 (36%), Gaps = 28/216 (12%)

Query: 189 REVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQS 248
           ++   A  T    +    S   P   +   P+ S+ +   P+S+ P   +A P +P   +
Sbjct: 163 QDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATT 222

Query: 249 PIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGP 308
           P PP    P       P   AT                     T A L S      TA P
Sbjct: 223 PAPPSSSAPPETTAAPPTPSAT---------------------TPAPLSSSAPPETTAVP 261

Query: 309 SAFNITSLISQAAQL---STQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPL 365
              + T+L   +A     +T A P+  +       + +P+   +  I+TP ++   + P 
Sbjct: 262 PTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPD 321

Query: 366 ISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQ 401
            S    +   + +T V  Q     + T+QP +A  Q
Sbjct: 322 TSETSAAPTHQTTTSVTTQ----TTTTKQPTSAPGQ 353



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 55/232 (23%), Positives = 87/232 (37%), Gaps = 20/232 (8%)

Query: 229 PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLT 288
           P   P  ++S V  + V  + IP +   P+   ++      T    N+    S+ N   +
Sbjct: 90  PPKHPDKNSSVVNPTLVATTQIPSVTF-PSASTKITTLPNVTFLPQNATTISSRENVNTS 148

Query: 289 AAV-TQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSY 347
           ++V T A + S   +  TA P   + T          T A PS+ +P   T+   +P + 
Sbjct: 149 SSVATLAPVNSPAPQDTTAAPPTPSAT----------TPAPPSSSAPPETTAAPPTPSAT 198

Query: 348 VS--PRISTP-QTNTVPIKPLIST--PPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQ 402
               P  S P +T   P  P  +T  PP SS P  +T      P   + T  P+++    
Sbjct: 199 TQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAA---PPTPSATTPAPLSSSAPP 255

Query: 403 GHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 454
               V P     +    S S  P  T+     S  T  P +S A    +  P
Sbjct: 256 ETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.120    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,757,495
Number of Sequences: 37866
Number of extensions: 1160238
Number of successful extensions: 12216
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 153
Number of HSP's successfully gapped in prelim test: 853
Number of HSP's that attempted gapping in prelim test: 8412
Number of HSP's gapped (non-prelim): 3662
length of query: 544
length of database: 18,247,518
effective HSP length: 107
effective length of query: 437
effective length of database: 14,195,856
effective search space: 6203589072
effective search space used: 6203589072
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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