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Search of human proteins with 18201896
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18201896 T-box 5 isoform 2 [Homo sapiens]
(349 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18201896 T-box 5 isoform 2 [Homo sapiens] 732 0.0
gi|18201892 T-box 5 isoform 1 [Homo sapiens] 684 0.0
gi|31652232 T-box 5 isoform 1 [Homo sapiens] 684 0.0
gi|18201894 T-box 5 isoform 3 [Homo sapiens] 582 e-166
gi|18129690 T-box 4 [Homo sapiens] 433 e-121
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens] 248 6e-66
gi|197333868 T-box 2 [Homo sapiens] 247 1e-65
gi|5174711 T-box 1 isoform B [Homo sapiens] 242 3e-64
gi|117676399 T-box transcription factor TBX20 [Homo sapiens] 241 5e-64
gi|18104952 T-box 1 isoform C [Homo sapiens] 241 9e-64
gi|18104950 T-box 1 isoform A [Homo sapiens] 240 1e-63
gi|18201900 T-box 6 [Homo sapiens] 240 1e-63
gi|47419907 T-box 3 protein isoform 2 [Homo sapiens] 236 2e-62
gi|32567784 T-box 10 [Homo sapiens] 234 1e-61
gi|122937456 T-box 18 [Homo sapiens] 227 1e-59
gi|55770860 T-box 15 [Homo sapiens] 223 2e-58
gi|122937388 MAX gene associated [Homo sapiens] 207 9e-54
gi|4507339 transcription factor T [Homo sapiens] 206 2e-53
gi|158187509 T-box 22 isoform 1 [Homo sapiens] 200 1e-51
gi|18375603 T-box 22 isoform 1 [Homo sapiens] 200 1e-51
gi|7019549 T-box 21 [Homo sapiens] 198 5e-51
gi|5730081 T-box, brain, 1 [Homo sapiens] 197 2e-50
gi|4827024 T-box 19 [Homo sapiens] 194 1e-49
gi|22538470 eomesodermin [Homo sapiens] 191 1e-48
gi|158187511 T-box 22 isoform 2 [Homo sapiens] 159 5e-39
gi|4885561 AMP-activated protein kinase beta 2 non-catalytic sub... 35 0.077
gi|5803167 splicing factor 3a, subunit 3 [Homo sapiens] 34 0.17
gi|4504001 connexin 43 [Homo sapiens] 31 1.4
gi|62821787 COBL-like 1 [Homo sapiens] 31 1.4
gi|54792138 helicase with zinc finger domain [Homo sapiens] 31 1.9
>gi|18201896 T-box 5 isoform 2 [Homo sapiens]
Length = 349
Score = 732 bits (1889), Expect = 0.0
Identities = 349/349 (100%), Positives = 349/349 (100%)
Query: 1 MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60
MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE
Sbjct: 1 MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60
Query: 61 RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120
RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK
Sbjct: 61 RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120
Query: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180
WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ
Sbjct: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180
Query: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240
PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD
Sbjct: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240
Query: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300
DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP
Sbjct: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300
Query: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKGECDHPWSICFLSYLFLSLGWG 349
SQDLLPPPNPYPLPQEHSQIYHCTKRKGECDHPWSICFLSYLFLSLGWG
Sbjct: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKGECDHPWSICFLSYLFLSLGWG 349
>gi|18201892 T-box 5 isoform 1 [Homo sapiens]
Length = 518
Score = 684 bits (1764), Expect = 0.0
Identities = 331/338 (97%), Positives = 332/338 (98%), Gaps = 4/338 (1%)
Query: 1 MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60
MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE
Sbjct: 1 MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60
Query: 61 RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120
RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK
Sbjct: 61 RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120
Query: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180
WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ
Sbjct: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180
Query: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240
PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD
Sbjct: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240
Query: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300
DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP
Sbjct: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300
Query: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKGE----CDHPW 334
SQDLLPPPNPYPLPQEHSQIYHCTKRK E DHP+
Sbjct: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPY 338
>gi|31652232 T-box 5 isoform 1 [Homo sapiens]
Length = 518
Score = 684 bits (1764), Expect = 0.0
Identities = 331/338 (97%), Positives = 332/338 (98%), Gaps = 4/338 (1%)
Query: 1 MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60
MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE
Sbjct: 1 MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE 60
Query: 61 RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120
RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK
Sbjct: 61 RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK 120
Query: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180
WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ
Sbjct: 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 180
Query: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240
PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD
Sbjct: 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD 240
Query: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300
DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP
Sbjct: 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP 300
Query: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKGE----CDHPW 334
SQDLLPPPNPYPLPQEHSQIYHCTKRK E DHP+
Sbjct: 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPY 338
>gi|18201894 T-box 5 isoform 3 [Homo sapiens]
Length = 468
Score = 582 bits (1500), Expect = e-166
Identities = 281/288 (97%), Positives = 282/288 (97%), Gaps = 4/288 (1%)
Query: 51 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 110
MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD
Sbjct: 1 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 60
Query: 111 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 170
DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH
Sbjct: 61 DHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
Query: 171 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 230
IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN
Sbjct: 121 IILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENN 180
Query: 231 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 290
PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ
Sbjct: 181 PFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQ 240
Query: 291 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKGE----CDHPW 334
YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRK E DHP+
Sbjct: 241 YQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPY 288
>gi|18129690 T-box 4 [Homo sapiens]
Length = 545
Score = 433 bits (1114), Expect = e-121
Identities = 225/329 (68%), Positives = 249/329 (75%), Gaps = 17/329 (5%)
Query: 28 PESALGAPSKS------PSSP-----QAAFTQQGMEGIKVFLHERELWLKFHEVGTEMII 76
PE AL AP S P P AA +Q +E IKV LHE+ELW KFHE GTEMII
Sbjct: 30 PEPALAAPGLSGAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMII 89
Query: 77 TKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLY 136
TKAGRRMFPSYKVKVTG+NPKTKYILL+DIVPADDHRYKF DNKW V GKAEPAMPGRLY
Sbjct: 90 TKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLY 149
Query: 137 VHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNGFGS 196
VHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENN FGS
Sbjct: 150 VHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGS 209
Query: 197 KNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYP 256
KNTAFCTHVFPET+FI+VTSYQNHKITQLKIENNPFAKGFRGSDD +L R++R+QSKEYP
Sbjct: 210 KNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDL-RVARLQSKEYP 268
Query: 257 VVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVS---GPSQDLLPPPNPYPL 313
V+ +S +RQ++ S + + L + YQ ENG QDL P + +P
Sbjct: 269 VISKSIMRQRLISPQLSATPDVGPLLGTHQALQHYQHENGAHSQLAEPQDL--PLSTFPT 326
Query: 314 PQEHSQIYHCTKRKGECDHPWSICFLSYL 342
++ S YHC KR+ H C SYL
Sbjct: 327 QRDSSLFYHCLKRRDGTRHLDLPCKRSYL 355
>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
Length = 723
Score = 248 bits (633), Expect = 6e-66
Identities = 131/252 (51%), Positives = 169/252 (67%), Gaps = 5/252 (1%)
Query: 55 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114
KV L +ELW +FH+ GTEM+ITK+GRRMFP +KV+ +GL+ K KYILLMDI+ ADD RY
Sbjct: 104 KVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRY 163
Query: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILN 174
KF +++W V GKA+P MP R+Y+HPDSPATG WM ++V+F KLKLTNN D G ILN
Sbjct: 164 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILN 223
Query: 175 SMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAK 234
SMHKYQPR HIV+A N+ + F T++FPET FIAVT+YQN KITQLKI+NNPFAK
Sbjct: 224 SMHKYQPRFHIVRA--NDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAK 281
Query: 235 GFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCE 294
GFR + + + ++ + V ++ S+ S SSE A + + S
Sbjct: 282 GFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDES--SSEQAAFNCFAQASSPAAST 339
Query: 295 NGVSGPSQDLLP 306
G S +DL P
Sbjct: 340 VGTSN-LKDLCP 350
>gi|197333868 T-box 2 [Homo sapiens]
Length = 712
Score = 247 bits (630), Expect = 1e-65
Identities = 121/183 (66%), Positives = 145/183 (79%), Gaps = 2/183 (1%)
Query: 55 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114
KV L +ELW +FH++GTEM+ITK+GRRMFP +KV+V+GL+ K KYILLMDIV ADD RY
Sbjct: 106 KVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRY 165
Query: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILN 174
KF +++W V GKA+P MP R+Y+HPDSPATG WM + V+F KLKLTNN D G ILN
Sbjct: 166 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILN 225
Query: 175 SMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAK 234
SMHKYQPR HIV+A N+ + F T+VFPET FIAVT+YQN KITQLKI+NNPFAK
Sbjct: 226 SMHKYQPRFHIVRA--NDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAK 283
Query: 235 GFR 237
GFR
Sbjct: 284 GFR 286
>gi|5174711 T-box 1 isoform B [Homo sapiens]
Length = 372
Score = 242 bits (618), Expect = 3e-64
Identities = 131/266 (49%), Positives = 175/266 (65%), Gaps = 15/266 (5%)
Query: 28 PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87
P ++ A +K+P A + G+ V L + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 89 PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143
Query: 88 KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145
+VK+ G++P Y+LLMD VP DD RY++A + W V GKA+PA PGR++ HPDSPA G
Sbjct: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203
Query: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202
A WM+Q+VSF KLKLTNN LD GHIILNSMH+YQPR H+V D ++ + +N F
Sbjct: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261
Query: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-S 261
T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR D + R R + P++ +
Sbjct: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFA 319
Query: 262 TVRQKVASNHSPFSSESRALSTSSNL 287
R VAS P +E ++ S L
Sbjct: 320 RSRNPVASPTQPSGTEKGLVTEGSGL 345
>gi|117676399 T-box transcription factor TBX20 [Homo sapiens]
Length = 447
Score = 241 bits (616), Expect = 5e-64
Identities = 141/312 (45%), Positives = 189/312 (60%), Gaps = 26/312 (8%)
Query: 26 SKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFP 85
S S+L P++P + M I L +ELW KFHE+GTEMIITK+GRRMFP
Sbjct: 74 SPSSSSLCTEPLIPTTP--IIPSEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFP 131
Query: 86 SYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK--WSVTGKAEPAMPGRLYVHPDSPA 143
+ +V +G++P+ KYI+LMDIVP D+ RY++A ++ W V GKA+P +P RLYVHPDSP
Sbjct: 132 TIRVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPF 191
Query: 144 TGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNG--FGSKNTAF 201
TG ++Q+VSF+K+KLTNN LD GHIILNSMHKYQPR+HI+K ++ K+ F
Sbjct: 192 TGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEF 251
Query: 202 CTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD---DMELHRM-SRMQSKEYPV 257
T +FPET F AVT+YQN IT+LKI++NPFAKGFR S D+E + S +Q Y
Sbjct: 252 RTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYAR 311
Query: 258 VPRSTV--RQKVASNHSPFS-SESRALSTSSNL-------------GSQYQCENGVSGPS 301
P T + V + S + + A +TS NL G Q+ G S
Sbjct: 312 SPIRTYGGEEDVLGDESQTTPNRGSAFTTSDNLSLSSWVSSSSSFPGFQHPQSLTALGTS 371
Query: 302 QDLLPPPNPYPL 313
+ P P+P+
Sbjct: 372 TASIATPIPHPI 383
>gi|18104952 T-box 1 isoform C [Homo sapiens]
Length = 495
Score = 241 bits (614), Expect = 9e-64
Identities = 130/259 (50%), Positives = 172/259 (66%), Gaps = 15/259 (5%)
Query: 28 PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87
P ++ A +K+P A + G+ V L + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 89 PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143
Query: 88 KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145
+VK+ G++P Y+LLMD VP DD RY++A + W V GKA+PA PGR++ HPDSPA G
Sbjct: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203
Query: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202
A WM+Q+VSF KLKLTNN LD GHIILNSMH+YQPR H+V D ++ + +N F
Sbjct: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261
Query: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-S 261
T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR D + R R + P++ +
Sbjct: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFA 319
Query: 262 TVRQKVASNHSPFSSESRA 280
R VAS P +E A
Sbjct: 320 RSRNPVASPTQPSGTEKDA 338
>gi|18104950 T-box 1 isoform A [Homo sapiens]
Length = 398
Score = 240 bits (613), Expect = 1e-63
Identities = 122/227 (53%), Positives = 159/227 (70%), Gaps = 12/227 (5%)
Query: 28 PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87
P ++ A +K+P A + G+ V L + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 89 PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143
Query: 88 KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145
+VK+ G++P Y+LLMD VP DD RY++A + W V GKA+PA PGR++ HPDSPA G
Sbjct: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203
Query: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202
A WM+Q+VSF KLKLTNN LD GHIILNSMH+YQPR H+V D ++ + +N F
Sbjct: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261
Query: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSR 249
T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR D + R R
Sbjct: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHR 308
>gi|18201900 T-box 6 [Homo sapiens]
Length = 436
Score = 240 bits (613), Expect = 1e-63
Identities = 114/202 (56%), Positives = 153/202 (75%), Gaps = 9/202 (4%)
Query: 38 SPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPK 97
+PS+P+A + + G+ + L RELW +F VGTEMIITKAGRRMFP+ +V VTGL+P+
Sbjct: 78 APSAPEALHS---LPGVSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPE 134
Query: 98 TKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQK 157
+Y+ L+D++P D RY++ +W +GKAEP +P R+Y+HPDSPATGAHWMRQ VSF +
Sbjct: 135 ARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHR 194
Query: 158 LKLTNNHLDPFGHIILNSMHKYQPRLHIVKADE--NNGFGSKNTAFCTHVFPETAFIAVT 215
+KLTN+ LDP GH+IL+SMHKYQPR+H+V+A + + +G + FPET FI+VT
Sbjct: 195 VKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWG----GMASFRFPETTFISVT 250
Query: 216 SYQNHKITQLKIENNPFAKGFR 237
+YQN +ITQLKI NPFAKGFR
Sbjct: 251 AYQNPQITQLKIAANPFAKGFR 272
>gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
Length = 743
Score = 236 bits (603), Expect = 2e-62
Identities = 131/272 (48%), Positives = 169/272 (62%), Gaps = 25/272 (9%)
Query: 55 KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114
KV L +ELW +FH+ GTEM+ITK+GRRMFP +KV+ +GL+ K KYILLMDI+ ADD RY
Sbjct: 104 KVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRY 163
Query: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFG----- 169
KF +++W V GKA+P MP R+Y+HPDSPATG WM ++V+F KLKLTNN D G
Sbjct: 164 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAF 223
Query: 170 ---------------HIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAV 214
ILNSMHKYQPR HIV+A N+ + F T++FPET FIAV
Sbjct: 224 PSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRA--NDILKLPYSTFRTYLFPETEFIAV 281
Query: 215 TSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPF 274
T+YQN KITQLKI+NNPFAKGFR + + + ++ + V ++ S+ S
Sbjct: 282 TAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDES-- 339
Query: 275 SSESRALSTSSNLGSQYQCENGVSGPSQDLLP 306
SSE A + + S G S +DL P
Sbjct: 340 SSEQAAFNCFAQASSPAASTVGTSN-LKDLCP 370
>gi|32567784 T-box 10 [Homo sapiens]
Length = 385
Score = 234 bits (596), Expect = 1e-61
Identities = 137/320 (42%), Positives = 185/320 (57%), Gaps = 31/320 (9%)
Query: 23 PCDSKPES-ALGAPS-KSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAG 80
PC S + A+ P+ + P +P+ + + V L + LW +F+++GTEMI+TKAG
Sbjct: 39 PCTSSTGAQAVAEPTGQGPKNPRVS-------RVTVQLEMKPLWEEFNQLGTEMIVTKAG 91
Query: 81 RRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVH 138
RRMFP ++VK+ G++ Y LLMD +P DD RY++A + W V GKA+PA PGR++ H
Sbjct: 92 RRMFPPFQVKILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFH 151
Query: 139 PDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFG 195
PDSPA GA WMRQ+VSF KLKLTNN LD GHIILNSMH+YQPR H+V D ++ +
Sbjct: 152 PDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSERYA 211
Query: 196 SKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEY 255
+N F + +F ET F AVT+YQNH+ITQLKI +NPFAKGFR SD +
Sbjct: 212 QEN--FKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRESD-----------LDSW 258
Query: 256 PVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPS---QDLLPPPNPYP 312
PV PR + A +HS S +T + P+ LLPPP
Sbjct: 259 PVAPRPLL-SVPARSHSSLSPCVLKGATDREKDPNKASASTSKTPAWLHHQLLPPPEVLL 317
Query: 313 LPQEHSQIYHCTKRKGECDH 332
P + + + + G H
Sbjct: 318 APATYRPVTYQSLYSGAPSH 337
>gi|122937456 T-box 18 [Homo sapiens]
Length = 607
Score = 227 bits (579), Expect = 1e-59
Identities = 119/246 (48%), Positives = 157/246 (63%), Gaps = 26/246 (10%)
Query: 5 DEGFGLAHTPL-EPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHEREL 63
++GF +PL P ++ + G P SP +P +V L EL
Sbjct: 101 EDGFQQGASPLASPGGSPKGSPARSLARPGTPLPSPQAP------------RVDLQGAEL 148
Query: 64 WLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKW 121
W +FHE+GTEMIITKAGRRMFP+ +VK++GL+P +Y + MDIVP D+ RY++ +KW
Sbjct: 149 WKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKW 208
Query: 122 SVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQP 181
V G A+ +P R+Y+HPDSPA+G WMRQ++SF KLKLTNN LD GHIIL+SMHKYQP
Sbjct: 209 MVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQP 268
Query: 182 RLHIVKADENNGF--------GSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233
R+H+++ D + G AF FPET F VT+YQN +IT+LKI+ NPFA
Sbjct: 269 RVHVIRKDCGDDLSPIKPVPSGEGVKAFS---FPETVFTTVTAYQNQQITRLKIDRNPFA 325
Query: 234 KGFRGS 239
KGFR S
Sbjct: 326 KGFRDS 331
>gi|55770860 T-box 15 [Homo sapiens]
Length = 496
Score = 223 bits (569), Expect = 2e-58
Identities = 109/196 (55%), Positives = 141/196 (71%), Gaps = 7/196 (3%)
Query: 51 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPAD 110
ME I+V L +LW +FH++GTEMIITKAGRRMFP+ +VK+TGL+P +Y + MDIVP D
Sbjct: 4 MEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVD 63
Query: 111 DHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPF 168
+ RY++ +KW V G A+ +P R+Y+HPDS A+G WMRQ+VSF KLKLTNN LD
Sbjct: 64 NKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQ 123
Query: 169 GHIILNSMHKYQPRLHIVKADENNGFGSK-----NTAFCTHVFPETAFIAVTSYQNHKIT 223
GHIIL+SMHKYQPR+H+++ D ++ T FPET F VT+YQN +IT
Sbjct: 124 GHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQIT 183
Query: 224 QLKIENNPFAKGFRGS 239
+LKI+ NPFAKGFR S
Sbjct: 184 RLKIDRNPFAKGFRDS 199
>gi|122937388 MAX gene associated [Homo sapiens]
Length = 3114
Score = 207 bits (528), Expect = 9e-54
Identities = 106/191 (55%), Positives = 133/191 (69%), Gaps = 11/191 (5%)
Query: 53 GIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDH 112
GI V L +W +F+ TEMI+TK GRRMFP + +TGL+ KYIL+MDI P D+H
Sbjct: 74 GITVTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDNH 133
Query: 113 RYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHII 172
RYK+ W +GKAEP + GR+++HP+SP+TG +WM Q VSF KLKLTNN LD GHII
Sbjct: 134 RYKWNGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHII 193
Query: 173 LNSMHKYQPRLHIVKAD------ENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLK 226
L+SMH+Y PRLH+V A+ + NG G T FP+T F AVT+YQN +ITQLK
Sbjct: 194 LHSMHRYLPRLHLVPAEKAVEVIQLNGPGVH-----TFTFPQTEFFAVTAYQNIQITQLK 248
Query: 227 IENNPFAKGFR 237
I+ NPFAKGFR
Sbjct: 249 IDYNPFAKGFR 259
>gi|4507339 transcription factor T [Homo sapiens]
Length = 435
Score = 206 bits (525), Expect = 2e-53
Identities = 117/267 (43%), Positives = 157/267 (58%), Gaps = 23/267 (8%)
Query: 54 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113
++V L E ELWL+F E+ EMI+TK GRRMFP KV V+GL+P Y L+D V AD+HR
Sbjct: 42 LRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHR 101
Query: 114 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 173
+K+ + +W GK EP P +Y+HPDSP GAHWM+ VSF K+KLTN L+ G I+L
Sbjct: 102 WKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNK-LNGGGQIML 160
Query: 174 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233
NS+HKY+PR+HIV+ G +H FPET FIAVT+YQN +IT LKI+ NPFA
Sbjct: 161 NSLHKYEPRIHIVRV------GGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFA 214
Query: 234 KGFRGSDDMELHR--MSRMQSKEYP-------VVPRSTVRQKVASNHSPFSSESRALSTS 284
K F + + H+ M + P ++P ++ A+ H F ALS
Sbjct: 215 KAFLDAKERSDHKEMMEEPGDSQQPGYSQWGWLLPGTSTLCPPANPHPQFGG---ALS-- 269
Query: 285 SNLGSQYQCENGVSGPSQDLLPPPNPY 311
L S + C+ + S P P+PY
Sbjct: 270 --LPSTHSCDRYPTLRSHRSSPYPSPY 294
>gi|158187509 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 200 bits (509), Expect = 1e-51
Identities = 123/301 (40%), Positives = 169/301 (56%), Gaps = 23/301 (7%)
Query: 14 PLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTE 73
PLE K P S S G+ S +S ++ + I++ L ELW +FH++GTE
Sbjct: 57 PLEKQPKTEPSTSA-SSGCGSDSGYGNSSESLEEKD----IQMELQGSELWKRFHDIGTE 111
Query: 74 MIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-A 130
MIITKAGRRMFPS +VKV GL+P +Y + +D+VP D RY++ ++W V G +
Sbjct: 112 MIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLC 171
Query: 131 MPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK--- 187
+ R YVHPDSP +G WMRQ++SF ++KLTNN +D GHIIL SMHKY+PR+H+++
Sbjct: 172 IIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGS 231
Query: 188 -ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHR 246
D + T F ET F VT+YQN +IT+LKIE NPFAKGFR D
Sbjct: 232 SVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR--DTGRNRG 289
Query: 247 MSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLP 306
+ + YP P T+ K F +++++ S+ S S G P LL
Sbjct: 290 VLDGLLETYPWRPSFTLDFKT------FGADTQSGSSGS---SPVTSSGGAPSPLNSLLS 340
Query: 307 P 307
P
Sbjct: 341 P 341
>gi|18375603 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 200 bits (509), Expect = 1e-51
Identities = 123/301 (40%), Positives = 169/301 (56%), Gaps = 23/301 (7%)
Query: 14 PLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTE 73
PLE K P S S G+ S +S ++ + I++ L ELW +FH++GTE
Sbjct: 57 PLEKQPKTEPSTSA-SSGCGSDSGYGNSSESLEEKD----IQMELQGSELWKRFHDIGTE 111
Query: 74 MIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-A 130
MIITKAGRRMFPS +VKV GL+P +Y + +D+VP D RY++ ++W V G +
Sbjct: 112 MIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLC 171
Query: 131 MPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK--- 187
+ R YVHPDSP +G WMRQ++SF ++KLTNN +D GHIIL SMHKY+PR+H+++
Sbjct: 172 IIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGS 231
Query: 188 -ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHR 246
D + T F ET F VT+YQN +IT+LKIE NPFAKGFR D
Sbjct: 232 SVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR--DTGRNRG 289
Query: 247 MSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLP 306
+ + YP P T+ K F +++++ S+ S S G P LL
Sbjct: 290 VLDGLLETYPWRPSFTLDFKT------FGADTQSGSSGS---SPVTSSGGAPSPLNSLLS 340
Query: 307 P 307
P
Sbjct: 341 P 341
>gi|7019549 T-box 21 [Homo sapiens]
Length = 535
Score = 198 bits (504), Expect = 5e-51
Identities = 107/190 (56%), Positives = 131/190 (68%), Gaps = 7/190 (3%)
Query: 54 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113
++V L+ LW KF++ TEMIITK GRRMFP V GL P + Y + +D+V D H
Sbjct: 137 LRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHH 196
Query: 114 YKFADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFG 169
+++ KW GKAE +MPG RLYVHPDSP TGAHWMRQ VSF KLKLTNN +
Sbjct: 197 WRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQ 256
Query: 170 HIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHV--FPETAFIAVTSYQNHKITQLKI 227
I+L S+HKYQPRLHIV+ ++ + N A TH+ F ET FIAVT+YQN +ITQLKI
Sbjct: 257 MIVLQSLHKYQPRLHIVEVNDGEPEAACN-ASNTHIFTFQETQFIAVTAYQNAEITQLKI 315
Query: 228 ENNPFAKGFR 237
+NNPFAKGFR
Sbjct: 316 DNNPFAKGFR 325
>gi|5730081 T-box, brain, 1 [Homo sapiens]
Length = 682
Score = 197 bits (500), Expect = 2e-50
Identities = 107/209 (51%), Positives = 141/209 (67%), Gaps = 13/209 (6%)
Query: 43 QAAFTQQGMEGIK--VFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKY 100
Q + TQ G+ K V+L R LWLKFH TEMIITK GRRMFP ++GL+P Y
Sbjct: 191 QFSSTQPGLVPGKAQVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHY 250
Query: 101 ILLMDIVPADDHRYKFADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLK 159
+ +D++ AD + ++F KW GKA+ + G R+Y+HPDSP TGAHWMRQ +SF KLK
Sbjct: 251 NIFVDVILADPNHWRFQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLK 310
Query: 160 LTNNHLDPFGH---IILNSMHKYQPRLHIVKADENNGFGSKNTA----FCTHVFPETAFI 212
LTNN + ++L S+HKYQPRLH+V+ +E+ G+++T+ T FPET FI
Sbjct: 311 LTNNKGASNNNGQMVVLQSLHKYQPRLHVVEVNED---GTEDTSQPGRVQTFTFPETQFI 367
Query: 213 AVTSYQNHKITQLKIENNPFAKGFRGSDD 241
AVT+YQN ITQLKI++NPFAKGFR + D
Sbjct: 368 AVTAYQNTDITQLKIDHNPFAKGFRDNYD 396
>gi|4827024 T-box 19 [Homo sapiens]
Length = 448
Score = 194 bits (492), Expect = 1e-49
Identities = 113/288 (39%), Positives = 156/288 (54%), Gaps = 32/288 (11%)
Query: 54 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 113
+++ L + LW +F EV EMI+TK GRRMFP K+ VTGL+P Y LL+D VP D HR
Sbjct: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
Query: 114 YKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIIL 173
+K+ + +W GK E + +Y+HPDSP GAHWM+ +SF K+KLTN L+ G I+L
Sbjct: 101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIML 159
Query: 174 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFA 233
NS+HKY+P++HIV+ GS + FPET FIAVT+YQN +IT LKI+ NPFA
Sbjct: 160 NSLHKYEPQVHIVRV------GSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFA 213
Query: 234 KGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC 293
K F L R ++ P SES+ ++ S G +
Sbjct: 214 KAF-------LDAKERNHLRDVPEA----------------ISESQHVTYSHLGGWIFSN 250
Query: 294 ENGV--SGPSQDLLPPPNPYPLPQEHSQIYHCTKRKGECDHPWSICFL 339
+GV +G S P P P P H H + +G P+ ++
Sbjct: 251 PDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQAPYPSAYM 298
>gi|22538470 eomesodermin [Homo sapiens]
Length = 686
Score = 191 bits (484), Expect = 1e-48
Identities = 103/192 (53%), Positives = 129/192 (67%), Gaps = 7/192 (3%)
Query: 56 VFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYK 115
V+L R LWLKFH TEMIITK GRRMFP + GLNP Y + +++V AD + ++
Sbjct: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328
Query: 116 FADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFGHI 171
F KW GKA+ M G ++YVHP+SP TG+HWMRQ +SF KLKLTNN + + I
Sbjct: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388
Query: 172 ILNSMHKYQPRLHIVKADENNGFGSKN--TAFCTHVFPETAFIAVTSYQNHKITQLKIEN 229
+L S+HKYQPRLHIV+ E +G N + T F ET FIAVT+YQN ITQLKI++
Sbjct: 389 VLQSLHKYQPRLHIVEVTE-DGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDH 447
Query: 230 NPFAKGFRGSDD 241
NPFAKGFR + D
Sbjct: 448 NPFAKGFRDNYD 459
>gi|158187511 T-box 22 isoform 2 [Homo sapiens]
Length = 400
Score = 159 bits (401), Expect = 5e-39
Identities = 94/232 (40%), Positives = 130/232 (56%), Gaps = 18/232 (7%)
Query: 83 MFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-AMPGRLYVHP 139
MFPS +VKV GL+P +Y + +D+VP D RY++ ++W V G + + R YVHP
Sbjct: 1 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 60
Query: 140 DSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK----ADENNGFG 195
DSP +G WMRQ++SF ++KLTNN +D GHIIL SMHKY+PR+H+++ D +
Sbjct: 61 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 120
Query: 196 SKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEY 255
T F ET F VT+YQN +IT+LKIE NPFAKGFR D + + Y
Sbjct: 121 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR--DTGRNRGVLDGLLETY 178
Query: 256 PVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLPP 307
P P T+ K F +++++ S+ S S G P LL P
Sbjct: 179 PWRPSFTLDFKT------FGADTQSGSSGS---SPVTSSGGAPSPLNSLLSP 221
>gi|4885561 AMP-activated protein kinase beta 2 non-catalytic
subunit [Homo sapiens]
Length = 272
Score = 35.4 bits (80), Expect = 0.077
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 8/102 (7%)
Query: 36 SKSPSSPQAAFTQQGME-GIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGL 94
SK P + QQ +E +K R +++ E G E+ I+ + F ++ K+ +
Sbjct: 51 SKLPGDKEFVSWQQDLEDSVKPTQQARPTVIRWSEGGKEVFISGS----FNNWSTKIPLI 106
Query: 95 NPKTKYILLMDIVPADDHRYK-FADNKWSVTGKAEPAMPGRL 135
++ ++D+ P +H+YK F D +W V +EP + +L
Sbjct: 107 KSHNDFVAILDL-PEGEHQYKFFVDGQW-VHDPSEPVVTSQL 146
>gi|5803167 splicing factor 3a, subunit 3 [Homo sapiens]
Length = 501
Score = 34.3 bits (77), Expect = 0.17
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 9/97 (9%)
Query: 243 ELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQ 302
E R+ + +KE + +ST+R ++ S+H + + R + S NL Y ++G+
Sbjct: 14 EKERLMDVMAKEM-LTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDLYDDKDGLRKEEL 72
Query: 303 DLLPPPNPYPLPQEHSQIYHCTKRKGEC--DHPWSIC 337
+ + PN E ++ Y+ K+ E HP IC
Sbjct: 73 NAISGPN------EFAEFYNRLKQIKEFHRKHPNEIC 103
>gi|4504001 connexin 43 [Homo sapiens]
Length = 382
Score = 31.2 bits (69), Expect = 1.4
Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 263 VRQKVASNHSPFSSESRALSTSSNLGSQ-YQCENGVSGPSQDLLPPPNP 310
V+ +V P+ + S ALS + + GSQ Y NG S P+ L P P
Sbjct: 236 VKDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPP 284
>gi|62821787 COBL-like 1 [Homo sapiens]
Length = 1166
Score = 31.2 bits (69), Expect = 1.4
Identities = 44/196 (22%), Positives = 72/196 (36%), Gaps = 23/196 (11%)
Query: 122 SVTGKAEPAMPGRLYVHPDSPATG-----AHWMRQLVSFQKLKLTNNHLDPFGHIILNSM 176
SV E G L +H + P T AH L L P I NS
Sbjct: 688 SVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDL------------LPPVDRIDKNST 735
Query: 177 HKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGF 236
Y + + D N N ++ P+ I +T+Y+ L+I + ++
Sbjct: 736 ASYLKNYPLYRQDYNPKPKPSNEITREYI-PK---IGMTTYKIVPPKSLEISKDWQSETI 791
Query: 237 RGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENG 296
DD ++H + + + E V + + A + SP L NL +++Q +
Sbjct: 792 EYKDDQDMHALGKKHTHEN-VKETAIQTEDSAISESP-EEPLPNLKPKPNLRTEHQVPSS 849
Query: 297 VSGPSQDLLPPPNPYP 312
VS P ++ P P P
Sbjct: 850 VSSPDDAMVSPLKPAP 865
>gi|54792138 helicase with zinc finger domain [Homo sapiens]
Length = 1942
Score = 30.8 bits (68), Expect = 1.9
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Query: 249 RMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQC-----ENGVSGPSQD 303
++QS+ P VP +S+ S F+ SR + +SN + + S PS+
Sbjct: 1609 QVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEH 1668
Query: 304 LLPPPNPYPLP 314
L PPP Y P
Sbjct: 1669 LAPPPLKYLAP 1679
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,319,308
Number of Sequences: 37866
Number of extensions: 743595
Number of successful extensions: 3219
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3122
Number of HSP's gapped (non-prelim): 87
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.