Guide to the Human Genome
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Name: GJA1 Sequence: fasta or formatted (382aa) NCBI GI: 4504001
Description:

connexin 43

Referenced in:

Gap Junctions and Tight Junctions

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.8         26           2
 C cysteine            2.4          9           1
 D aspartate           4.7         18           2
 E glutamate           4.7         18           3
 F phenylalanine       5.5         21           2
 G glycine             6.0         23           2
 H histidine           2.1          8           1
 I isoleucine          5.8         22           2
 K lysine              7.3         28           2
 L leucine             8.9         34           3
 M methionine          1.8          7           1
 N asparagine          4.2         16           2
 P proline             5.0         19           2
 Q glutamine           4.7         18           2
 R arginine            4.5         17           1
 S serine              9.7         37           2
 T threonine           3.4         13           1
 V valine              6.8         26           2
 W tryptophan          1.6          6           1
 Y tyrosine            4.2         16           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   connexin 43 
GJA4                  0.369   connexin 37 
GJA3                  0.365   connexin 46 
GJA8                  0.325   connexin 50 
GJA5                  0.321   connexin 40 
GJA5                  0.321   connexin 40 
GJA10                 0.297   gap junction protein, alpha 10 
GJA9                  0.292   gap junction protein, alpha 9, 59kDa 
GJC1                  0.255   connexin 45 
GJC1                  0.255   connexin 45 
GJB1                  0.242   gap junction protein, beta 1, 32kDa 
GJB1                  0.242   gap junction protein, beta 1, 32kDa 
GJB2                  0.242   gap junction protein beta 2 
GJB6                  0.240   gap junction protein, beta 6 
GJB6                  0.240   gap junction protein, beta 6 
GJB6                  0.240   gap junction protein, beta 6 
GJB6                  0.240   gap junction protein, beta 6 
GJC2                  0.234   gap junction protein, gamma 2, 47kDa 
GJB3                  0.218   connexin 31 
GJB3                  0.218   connexin 31 
GJB4                  0.216   gap junction protein, beta 4 
GJB7                  0.211   gap junction protein, beta 7, 25kDa 
GJD2                  0.211   gap junction protein, delta 2, 36kDa 
GJB5                  0.207   gap junction protein, beta 5, 31.1kDa 
GJD3                  0.194   gap junction protein, delta 3, 31.9kDa 
GJC3                  0.147   gap junction protein, gamma 3, 30.2kDa 
GJD4                  0.139   connexin40.1 
LOC100128334          0.081   PREDICTED: similar to hCG1770601 
LOC100128334          0.081   PREDICTED: similar to hCG1770601 
LOC100128334          0.081   PREDICTED: similar to hCG1770601 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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