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Search of human proteins with 18201890
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18201890 hypothetical protein LOC140894 [Homo sapiens]
(572 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18201890 hypothetical protein LOC140894 [Homo sapiens] 1158 0.0
gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isof... 59 9e-09
gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isof... 59 9e-09
gi|148612818 protein kinase, cGMP-dependent, type I isoform 1 [H... 59 2e-08
gi|10835242 protein kinase, cGMP-dependent, type I isoform 2 [Ho... 59 2e-08
gi|148747862 Rap guanine nucleotide exchange factor 3 isoform b ... 58 2e-08
gi|20070215 Rap guanine nucleotide exchange factor 3 isoform b [... 58 2e-08
gi|148747859 Rap guanine nucleotide exchange factor 3 isoform a ... 58 2e-08
gi|5453978 protein kinase, cGMP-dependent, type II [Homo sapiens] 52 2e-06
gi|27734929 cyclic nucleotide binding domain containing 1 [Homo ... 47 6e-05
gi|54633319 PDZ domain-containing guanine nucleotide exchange fa... 44 5e-04
gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchan... 40 0.006
gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens] 40 0.006
gi|47132583 cAMP-dependent protein kinase, regulatory subunit al... 40 0.008
gi|47132581 cAMP-dependent protein kinase, regulatory subunit al... 40 0.008
gi|4506063 cAMP-dependent protein kinase, regulatory subunit alp... 40 0.008
gi|42718011 cyclic nucleotide gated channel alpha 2 [Homo sapiens] 39 0.010
gi|38257139 protein kinase, cAMP-dependent, regulatory, type I, ... 38 0.022
gi|4758958 cAMP-dependent protein kinase, regulatory subunit alp... 37 0.037
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 37 0.064
gi|120433600 cyclic nucleotide gated channel alpha 3 isoform 2 [... 33 0.92
gi|4502917 cyclic nucleotide gated channel alpha 3 isoform 1 [Ho... 33 0.92
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [... 32 1.2
gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [H... 32 1.2
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 32 1.6
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 32 1.6
gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens] 32 1.6
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 31 2.7
gi|239753937 PREDICTED: similar to hCG2036828 [Homo sapiens] 31 2.7
gi|112421013 signal-induced proliferation-associated 1 like 2 [H... 30 4.6
>gi|18201890 hypothetical protein LOC140894 [Homo sapiens]
Length = 572
Score = 1158 bits (2996), Expect = 0.0
Identities = 572/572 (100%), Positives = 572/572 (100%)
Query: 1 MRRHMVTYAWQLLKKELGLYQLAMDIIIMIRVCKMFRQGLRGFREYQIIETAHWKHPIFS 60
MRRHMVTYAWQLLKKELGLYQLAMDIIIMIRVCKMFRQGLRGFREYQIIETAHWKHPIFS
Sbjct: 1 MRRHMVTYAWQLLKKELGLYQLAMDIIIMIRVCKMFRQGLRGFREYQIIETAHWKHPIFS 60
Query: 61 FWDKKMQSRVTFDTMDFIAEEGHFPPKAIQIMQKKPSWRTEDEIQAVCNILQVLDSYRNY 120
FWDKKMQSRVTFDTMDFIAEEGHFPPKAIQIMQKKPSWRTEDEIQAVCNILQVLDSYRNY
Sbjct: 61 FWDKKMQSRVTFDTMDFIAEEGHFPPKAIQIMQKKPSWRTEDEIQAVCNILQVLDSYRNY 120
Query: 121 AEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKL 180
AEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKL
Sbjct: 121 AEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKL 180
Query: 181 LHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRK 240
LHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRK
Sbjct: 181 LHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRK 240
Query: 241 MELFASWSDEKLWQLVAMAKIERFSYGQLISKDFGESPFIMFISKGSCEVLRLLDLGASP 300
MELFASWSDEKLWQLVAMAKIERFSYGQLISKDFGESPFIMFISKGSCEVLRLLDLGASP
Sbjct: 241 MELFASWSDEKLWQLVAMAKIERFSYGQLISKDFGESPFIMFISKGSCEVLRLLDLGASP 300
Query: 301 SYRRWIWQHLELIDGRPLKTHLSEYSPMERFKEFQIKSYPLQDFSSLKLPHLKKAWGLQG 360
SYRRWIWQHLELIDGRPLKTHLSEYSPMERFKEFQIKSYPLQDFSSLKLPHLKKAWGLQG
Sbjct: 301 SYRRWIWQHLELIDGRPLKTHLSEYSPMERFKEFQIKSYPLQDFSSLKLPHLKKAWGLQG 360
Query: 361 TSFSRKIRTSGDTLSKMLGPKIQSRPAQSIKCAMINIKPGELPKEAAVGAYVKVHTVEQG 420
TSFSRKIRTSGDTLSKMLGPKIQSRPAQSIKCAMINIKPGELPKEAAVGAYVKVHTVEQG
Sbjct: 361 TSFSRKIRTSGDTLSKMLGPKIQSRPAQSIKCAMINIKPGELPKEAAVGAYVKVHTVEQG 420
Query: 421 EILAFLPEGECDTRPLILMSLGNELIRIRKEIFYELIDNDDEMIKKLLKLNIAFPSDEDM 480
EILAFLPEGECDTRPLILMSLGNELIRIRKEIFYELIDNDDEMIKKLLKLNIAFPSDEDM
Sbjct: 421 EILAFLPEGECDTRPLILMSLGNELIRIRKEIFYELIDNDDEMIKKLLKLNIAFPSDEDM 480
Query: 481 CQKFLQQNSWNIFRKDLLQLLVEPCQSQLFTPNRPKKREIYNPKSVVLDLCSINKTTKPR 540
CQKFLQQNSWNIFRKDLLQLLVEPCQSQLFTPNRPKKREIYNPKSVVLDLCSINKTTKPR
Sbjct: 481 CQKFLQQNSWNIFRKDLLQLLVEPCQSQLFTPNRPKKREIYNPKSVVLDLCSINKTTKPR 540
Query: 541 YPIFMAPQKYLPPLRIVQAIKAPRYKIRELLA 572
YPIFMAPQKYLPPLRIVQAIKAPRYKIRELLA
Sbjct: 541 YPIFMAPQKYLPPLRIVQAIKAPRYKIRELLA 572
>gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isoform
b [Homo sapiens]
Length = 867
Score = 59.3 bits (142), Expect = 9e-09
Identities = 50/187 (26%), Positives = 96/187 (51%), Gaps = 16/187 (8%)
Query: 46 YQIIETAHWKHPIFSFWDKKMQSRVTFDTMDFIAEEGHFPPKAIQ--IMQKKPSWRTEDE 103
Y+ ++ H P+ + +KK DTM +++ G P A I++K P RT D+
Sbjct: 143 YRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMG---PDAHMRMILRKPPGQRTVDD 199
Query: 104 IQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRR-RVIIKKGQKGNSFYFIYLGTVA 162
++ + L + + + + ++ LA V+ FE + V+ +G++G S+Y I G+V
Sbjct: 200 LEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVN 259
Query: 163 ITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEET-EFLVVDREDFFAN 221
+ G LH+G FG++ +++ + R ++IV E+ FL VD+EDF N
Sbjct: 260 VVIYGKGVVC-------TLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDF--N 310
Query: 222 KLDQEVQ 228
++ ++V+
Sbjct: 311 RILRDVE 317
>gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isoform
a [Homo sapiens]
Length = 1011
Score = 59.3 bits (142), Expect = 9e-09
Identities = 50/187 (26%), Positives = 96/187 (51%), Gaps = 16/187 (8%)
Query: 46 YQIIETAHWKHPIFSFWDKKMQSRVTFDTMDFIAEEGHFPPKAIQ--IMQKKPSWRTEDE 103
Y+ ++ H P+ + +KK DTM +++ G P A I++K P RT D+
Sbjct: 287 YRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMG---PDAHMRMILRKPPGQRTVDD 343
Query: 104 IQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRR-RVIIKKGQKGNSFYFIYLGTVA 162
++ + L + + + + ++ LA V+ FE + V+ +G++G S+Y I G+V
Sbjct: 344 LEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVN 403
Query: 163 ITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEET-EFLVVDREDFFAN 221
+ G LH+G FG++ +++ + R ++IV E+ FL VD+EDF N
Sbjct: 404 VVIYGKGVVC-------TLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDF--N 454
Query: 222 KLDQEVQ 228
++ ++V+
Sbjct: 455 RILRDVE 461
Score = 40.4 bits (93), Expect = 0.004
Identities = 30/137 (21%), Positives = 63/137 (45%), Gaps = 12/137 (8%)
Query: 89 IQIMQKKPSWRTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQ 148
I + K+P R+ +++ + L+ + ++ + L + +E + + ++G
Sbjct: 16 IACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGD 75
Query: 149 KGNSFYFIYLGTVAITKDEDGSSAFLDPHPKL-----LHKGSCFGEMDVLHASVRRSTIV 203
G ++Y + G++ + E S H L G+ FGE +L + R +TIV
Sbjct: 76 IGTNWYAVLAGSLDVKVSETSS------HQDAVTICTLGIGTAFGE-SILDNTPRHATIV 128
Query: 204 CMEETEFLVVDREDFFA 220
E +E L ++++DF A
Sbjct: 129 TRESSELLRIEQKDFKA 145
>gi|148612818 protein kinase, cGMP-dependent, type I isoform 1 [Homo
sapiens]
Length = 671
Score = 58.5 bits (140), Expect = 2e-08
Identities = 46/175 (26%), Positives = 84/175 (48%), Gaps = 19/175 (10%)
Query: 111 LQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGS 170
L+ + ++++ E + LA V+ + II++G +G++F+ I GTV +T+++ S
Sbjct: 216 LKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPS 275
Query: 171 SAFLDP-HPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF---------FA 220
DP + L KG FGE + VR + ++ E LV+DR+ F +
Sbjct: 276 E---DPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVS 332
Query: 221 NKLDQEVQKDAQYRFE--FFRKMELFASWSDEKLWQLVAMAKIERFSYGQLISKD 273
NK ++ + A+Y E FF ++L SD + + + R QL S++
Sbjct: 333 NKAYEDAEAKAKYEAEAAFFANLKL----SDFNIIDTLGVGGFGRVELVQLKSEE 383
Score = 54.7 bits (130), Expect = 2e-07
Identities = 45/188 (23%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Query: 137 FGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHAS 196
+G+ IIK+G G+ Y + G V +TK E + P G FGE+ +L+
Sbjct: 124 YGKDSCIIKEGDVGSLVYVMEDGKVEVTK-EGVKLCTMGP-------GKVFGELAILYNC 175
Query: 197 VRRSTIVCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRKMELFASWSDEKLWQLV 256
R +T+ + + +DR+ F + + K +Y EF + + F S +E L +L
Sbjct: 176 TRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEY-MEFLKSVPTFQSLPEEILSKLA 234
Query: 257 AMAKIERFSYGQLISKDFGESPFIMFISKGSCEVLRLLDLGASPSYRRWI----WQHLEL 312
+ + + G+ I + ISKG+ V R P + R + W +
Sbjct: 235 DVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKA 294
Query: 313 IDGRPLKT 320
+ G ++T
Sbjct: 295 LQGEDVRT 302
>gi|10835242 protein kinase, cGMP-dependent, type I isoform 2 [Homo
sapiens]
Length = 686
Score = 58.5 bits (140), Expect = 2e-08
Identities = 46/175 (26%), Positives = 84/175 (48%), Gaps = 19/175 (10%)
Query: 111 LQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGS 170
L+ + ++++ E + LA V+ + II++G +G++F+ I GTV +T+++ S
Sbjct: 231 LKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPS 290
Query: 171 SAFLDP-HPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF---------FA 220
DP + L KG FGE + VR + ++ E LV+DR+ F +
Sbjct: 291 E---DPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVS 347
Query: 221 NKLDQEVQKDAQYRFE--FFRKMELFASWSDEKLWQLVAMAKIERFSYGQLISKD 273
NK ++ + A+Y E FF ++L SD + + + R QL S++
Sbjct: 348 NKAYEDAEAKAKYEAEAAFFANLKL----SDFNIIDTLGVGGFGRVELVQLKSEE 398
Score = 54.7 bits (130), Expect = 2e-07
Identities = 45/188 (23%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Query: 137 FGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHAS 196
+G+ IIK+G G+ Y + G V +TK E + P G FGE+ +L+
Sbjct: 139 YGKDSCIIKEGDVGSLVYVMEDGKVEVTK-EGVKLCTMGP-------GKVFGELAILYNC 190
Query: 197 VRRSTIVCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRKMELFASWSDEKLWQLV 256
R +T+ + + +DR+ F + + K +Y EF + + F S +E L +L
Sbjct: 191 TRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEY-MEFLKSVPTFQSLPEEILSKLA 249
Query: 257 AMAKIERFSYGQLISKDFGESPFIMFISKGSCEVLRLLDLGASPSYRRWI----WQHLEL 312
+ + + G+ I + ISKG+ V R P + R + W +
Sbjct: 250 DVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKA 309
Query: 313 IDGRPLKT 320
+ G ++T
Sbjct: 310 LQGEDVRT 317
>gi|148747862 Rap guanine nucleotide exchange factor 3 isoform b
[Homo sapiens]
Length = 881
Score = 58.2 bits (139), Expect = 2e-08
Identities = 38/139 (27%), Positives = 75/139 (53%), Gaps = 11/139 (7%)
Query: 92 MQKKPSWRTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRR-RVIIKKGQKG 150
++K P RT++E+ + L + + + + ++ LA V+ FE + V+ +G KG
Sbjct: 179 LRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKG 238
Query: 151 NSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEET-E 209
S+Y I+ G+V + G LH+G FG++ +++ + R +TI+ E+
Sbjct: 239 TSWYIIWKGSVNVVTHGKGLVT-------TLHEGDDFGQLALVNDAPRAATIILREDNCH 291
Query: 210 FLVVDREDFFANKLDQEVQ 228
FL VD++DF N++ ++V+
Sbjct: 292 FLRVDKQDF--NRIIKDVE 308
>gi|20070215 Rap guanine nucleotide exchange factor 3 isoform b
[Homo sapiens]
Length = 881
Score = 58.2 bits (139), Expect = 2e-08
Identities = 38/139 (27%), Positives = 75/139 (53%), Gaps = 11/139 (7%)
Query: 92 MQKKPSWRTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRR-RVIIKKGQKG 150
++K P RT++E+ + L + + + + ++ LA V+ FE + V+ +G KG
Sbjct: 179 LRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKG 238
Query: 151 NSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEET-E 209
S+Y I+ G+V + G LH+G FG++ +++ + R +TI+ E+
Sbjct: 239 TSWYIIWKGSVNVVTHGKGLVT-------TLHEGDDFGQLALVNDAPRAATIILREDNCH 291
Query: 210 FLVVDREDFFANKLDQEVQ 228
FL VD++DF N++ ++V+
Sbjct: 292 FLRVDKQDF--NRIIKDVE 308
>gi|148747859 Rap guanine nucleotide exchange factor 3 isoform a
[Homo sapiens]
Length = 923
Score = 58.2 bits (139), Expect = 2e-08
Identities = 38/139 (27%), Positives = 75/139 (53%), Gaps = 11/139 (7%)
Query: 92 MQKKPSWRTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRR-RVIIKKGQKG 150
++K P RT++E+ + L + + + + ++ LA V+ FE + V+ +G KG
Sbjct: 221 LRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKG 280
Query: 151 NSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEET-E 209
S+Y I+ G+V + G LH+G FG++ +++ + R +TI+ E+
Sbjct: 281 TSWYIIWKGSVNVVTHGKGLVT-------TLHEGDDFGQLALVNDAPRAATIILREDNCH 333
Query: 210 FLVVDREDFFANKLDQEVQ 228
FL VD++DF N++ ++V+
Sbjct: 334 FLRVDKQDF--NRIIKDVE 350
>gi|5453978 protein kinase, cGMP-dependent, type II [Homo sapiens]
Length = 762
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/149 (24%), Positives = 73/149 (48%), Gaps = 11/149 (7%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTI 202
IIK+G+ GN + + G + + + E S+ + + FGE+ +L+ R +++
Sbjct: 195 IIKQGEPGNHIFVLAEGRLEVFQGEKLLSS--------IPMWTTFGELAILYNCTRTASV 246
Query: 203 VCMEETEFLVVDREDFFANKLDQEVQ-KDAQYRFEFFRKMELFASWSDEKLWQLVAMAKI 261
+ + +DRE F N + + Q +D QYR F R + L + ++KL +++ ++
Sbjct: 247 KAITNVKTWALDRE-VFQNIMRRTAQARDEQYR-NFLRSVSLLKNLPEDKLTKIIDCLEV 304
Query: 262 ERFSYGQLISKDFGESPFIMFISKGSCEV 290
E + G I ++ E ++KG +V
Sbjct: 305 EYYDKGDYIIREGEEGSTFFILAKGKVKV 333
Score = 51.6 bits (122), Expect = 2e-06
Identities = 46/178 (25%), Positives = 80/178 (44%), Gaps = 15/178 (8%)
Query: 115 DSYRNYAEPLQLL-------LAKV---MRFERFGRRRVIIKKGQKGNSFYFIYLGTVAIT 164
+ YRN+ + LL L K+ + E + + II++G++G++F+ + G V +T
Sbjct: 275 EQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVT 334
Query: 165 KDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCME-ETEFLVVDREDFFAN-K 222
+ +G K L KG FGE ++ VR + I+ E + LV+DRE F
Sbjct: 335 QSTEGHDQ--PQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVG 392
Query: 223 LDQEVQKDAQ-YRFEFFRKMELFASWSDEKLWQLVAMAKIERFSYGQLISKDFGESPF 279
+E+QK + Y R E + W+L +E + +++ SPF
Sbjct: 393 TFEELQKYLEGYVANLNRDDEKRHAKRSMSNWKLSKALSLEMIQLKEKVARFSSSSPF 450
>gi|27734929 cyclic nucleotide binding domain containing 1 [Homo
sapiens]
Length = 436
Score = 46.6 bits (109), Expect = 6e-05
Identities = 25/131 (19%), Positives = 64/131 (48%), Gaps = 4/131 (3%)
Query: 165 KDEDGSSAFLDPHPKLLHKGSCFGEMDVL---HASVRRSTIVCMEETEFLVVDREDFFAN 221
K+ + +L + +L K S FG ++V+ + + ++V ++ E L + + +
Sbjct: 242 KNSTLAEMYLPSYDSMLSKWSTFGTLEVMPQNESETQMFSVVTEDDCEILKIPAKGYAKI 301
Query: 222 KLDQEVQKDAQYRFEFFRKMELFASWSDEKLWQLVAMAKIERFSYGQLISKDFGESPFIM 281
K +++++ + + + R + W +++L+A+ K ++F G +I + F+
Sbjct: 302 K-EEKIKLENMQKLKLIRMCPYYEEWPTLSIYELIALLKWKKFPPGHVIVESGNIISFVG 360
Query: 282 FISKGSCEVLR 292
+I+ G C + R
Sbjct: 361 YINSGCCNIYR 371
>gi|54633319 PDZ domain-containing guanine nucleotide exchange
factor I [Homo sapiens]
Length = 1601
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/136 (23%), Positives = 69/136 (50%), Gaps = 18/136 (13%)
Query: 90 QIMQKKPSWRTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRR-RVIIKKGQ 148
+ ++K+P+ +T+D+I+ + + L ++ N ++ L VM FE + +I++ GQ
Sbjct: 254 ECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQ 313
Query: 149 KGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFG-----EMDVLHASVRRSTIV 203
+ +S+Y I GTV I+ D + L G+ FG + +H VR
Sbjct: 314 ELDSWYVILNGTVEISHP--------DGKVENLFMGNSFGITPTLDKQYMHGIVRTK--- 362
Query: 204 CMEETEFLVVDREDFF 219
+++ +F+ + ++D++
Sbjct: 363 -VDDCQFVCIAQQDYW 377
Score = 36.2 bits (82), Expect = 0.084
Identities = 19/78 (24%), Positives = 38/78 (48%)
Query: 86 PKAIQIMQKKPSWRTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIK 145
P A Q ++KKP RT +++ + + L ++ N E L++ R+ER+ +V+
Sbjct: 7 PGARQALRKKPPERTPEDLNTIYSYLHGMEILSNLREHQLRLMSARARYERYSGNQVLFC 66
Query: 146 KGQKGNSFYFIYLGTVAI 163
+Y + G+V +
Sbjct: 67 SETIARCWYILLSGSVLV 84
>gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchange
factor 2, partial [Homo sapiens]
Length = 803
Score = 40.0 bits (92), Expect = 0.006
Identities = 31/144 (21%), Positives = 72/144 (50%), Gaps = 16/144 (11%)
Query: 92 MQKKPSWRTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRF---ERFGRRRVIIKKGQ 148
++K P RT+D+I+ + + L ++ N ++ L VM F ER G +++ G+
Sbjct: 111 LEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAG--TIVLNDGE 168
Query: 149 KGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTI-VCMEE 207
+ +S+ I G+V +T + D ++L G+ FG + + + +++
Sbjct: 169 ELDSWSVILNGSVEVT--------YPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDD 220
Query: 208 TEFLVVDREDF--FANKLDQEVQK 229
+F+ + ++D+ N++++ +QK
Sbjct: 221 CQFVCIAQQDYCRILNQVEKNMQK 244
>gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]
Length = 1499
Score = 40.0 bits (92), Expect = 0.006
Identities = 31/144 (21%), Positives = 72/144 (50%), Gaps = 16/144 (11%)
Query: 92 MQKKPSWRTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRF---ERFGRRRVIIKKGQ 148
++K P RT+D+I+ + + L ++ N ++ L VM F ER G +++ G+
Sbjct: 111 LEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAG--TIVLNDGE 168
Query: 149 KGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTI-VCMEE 207
+ +S+ I G+V +T + D ++L G+ FG + + + +++
Sbjct: 169 ELDSWSVILNGSVEVT--------YPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDD 220
Query: 208 TEFLVVDREDF--FANKLDQEVQK 229
+F+ + ++D+ N++++ +QK
Sbjct: 221 CQFVCIAQQDYCRILNQVEKNMQK 244
>gi|47132583 cAMP-dependent protein kinase, regulatory subunit alpha
1 [Homo sapiens]
Length = 381
Score = 39.7 bits (91), Expect = 0.008
Identities = 33/151 (21%), Positives = 69/151 (45%), Gaps = 11/151 (7%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTI 202
+I++G +G++FY I G + + + +++ + +G FGE+ +++ + R +T+
Sbjct: 164 VIQQGDEGDNFYVIDQGETDVYVNNEWATS--------VGEGGSFGELALIYGTPRAATV 215
Query: 203 VCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRKMELFASWSD-EKLWQLVAMAKI 261
+ +DR+ + + ++K Y EF K+ + S E+L A+ +
Sbjct: 216 KAKTNVKLWGIDRDSYRRILMGSTLRKRKMYE-EFLSKVSILESLDKWERLTVADALEPV 274
Query: 262 ERFSYGQLISKDFGESPFIMFISKGSCEVLR 292
+ F GQ I I +GS VL+
Sbjct: 275 Q-FEDGQKIVVQGEPGDEFFIILEGSAAVLQ 304
>gi|47132581 cAMP-dependent protein kinase, regulatory subunit alpha
1 [Homo sapiens]
Length = 381
Score = 39.7 bits (91), Expect = 0.008
Identities = 33/151 (21%), Positives = 69/151 (45%), Gaps = 11/151 (7%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTI 202
+I++G +G++FY I G + + + +++ + +G FGE+ +++ + R +T+
Sbjct: 164 VIQQGDEGDNFYVIDQGETDVYVNNEWATS--------VGEGGSFGELALIYGTPRAATV 215
Query: 203 VCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRKMELFASWSD-EKLWQLVAMAKI 261
+ +DR+ + + ++K Y EF K+ + S E+L A+ +
Sbjct: 216 KAKTNVKLWGIDRDSYRRILMGSTLRKRKMYE-EFLSKVSILESLDKWERLTVADALEPV 274
Query: 262 ERFSYGQLISKDFGESPFIMFISKGSCEVLR 292
+ F GQ I I +GS VL+
Sbjct: 275 Q-FEDGQKIVVQGEPGDEFFIILEGSAAVLQ 304
>gi|4506063 cAMP-dependent protein kinase, regulatory subunit alpha
1 [Homo sapiens]
Length = 381
Score = 39.7 bits (91), Expect = 0.008
Identities = 33/151 (21%), Positives = 69/151 (45%), Gaps = 11/151 (7%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTI 202
+I++G +G++FY I G + + + +++ + +G FGE+ +++ + R +T+
Sbjct: 164 VIQQGDEGDNFYVIDQGETDVYVNNEWATS--------VGEGGSFGELALIYGTPRAATV 215
Query: 203 VCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRKMELFASWSD-EKLWQLVAMAKI 261
+ +DR+ + + ++K Y EF K+ + S E+L A+ +
Sbjct: 216 KAKTNVKLWGIDRDSYRRILMGSTLRKRKMYE-EFLSKVSILESLDKWERLTVADALEPV 274
Query: 262 ERFSYGQLISKDFGESPFIMFISKGSCEVLR 292
+ F GQ I I +GS VL+
Sbjct: 275 Q-FEDGQKIVVQGEPGDEFFIILEGSAAVLQ 304
>gi|42718011 cyclic nucleotide gated channel alpha 2 [Homo sapiens]
Length = 664
Score = 39.3 bits (90), Expect = 0.010
Identities = 48/204 (23%), Positives = 88/204 (43%), Gaps = 24/204 (11%)
Query: 90 QIMQKKPS-WRTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQ 148
+I++ P+ R E I + L+ + + + L + L +R + F I +KG
Sbjct: 427 EILKNLPAKLRAEIAINVHLSTLKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGD 486
Query: 149 KGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLH-----------ASV 197
G Y I G +A+ D DG + + LL GSCFGE+ +L+ A++
Sbjct: 487 IGKEMYIIKEGKLAVVAD-DGVTQYA-----LLSAGSCFGEISILNIKGSKMGNRRTANI 540
Query: 198 RR---STIVCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRKMELFASWS---DEK 251
R S + C+ + + + E A K+ +E ++ + + E+ S EK
Sbjct: 541 RSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVATSMEVDVQEK 600
Query: 252 LWQLVAMAKIERFSYGQLISKDFG 275
L QL + +G+L+++ G
Sbjct: 601 LGQLETNMETLYTRFGRLLAEYTG 624
>gi|38257139 protein kinase, cAMP-dependent, regulatory, type I,
beta [Homo sapiens]
Length = 381
Score = 38.1 bits (87), Expect = 0.022
Identities = 32/152 (21%), Positives = 70/152 (46%), Gaps = 13/152 (8%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTI 202
+I++G +G++FY + G V + + + + + +G FGE+ +++ + R +T+
Sbjct: 164 VIQQGNEGDNFYVVDQGEVDVYVNGEWVTN--------ISEGGSFGELALIYGTPRAATV 215
Query: 203 VCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRKMELFASWSDEKLWQLVAMAKIE 262
+ + +DR+ + + ++K Y EF K+ + S EK +L +E
Sbjct: 216 KAKTDLKLWGIDRDSYRRILMGSTLRKRKMYE-EFLSKVSILESL--EKWERLTVADALE 272
Query: 263 --RFSYGQLISKDFGESPFIMFISKGSCEVLR 292
+F G+ I I++G+ VL+
Sbjct: 273 PVQFEDGEKIVVQGEPGDDFYIITEGTASVLQ 304
Score = 32.7 bits (73), Expect = 0.92
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 102 DEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYLGTV 161
+E + +IL+ L+ + +L +A + +F I+ +G+ G+ FY I GT
Sbjct: 247 EEFLSKVSILESLEKWE------RLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTA 300
Query: 162 AITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF 218
++ + + +++ L FGE+ +L R +T+V + + +DR F
Sbjct: 301 SVLQRRSPNEEYVE--VGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRF 355
>gi|4758958 cAMP-dependent protein kinase, regulatory subunit alpha
2 [Homo sapiens]
Length = 404
Score = 37.4 bits (85), Expect = 0.037
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 5/149 (3%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTI 202
+I +G G++FY I GT I +D + + + ++GS FGE+ +++ + R +TI
Sbjct: 166 VIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYD---NRGS-FGELALMYNTPRAATI 221
Query: 203 VCMEETEFLVVDREDFFANKLDQEVQKDAQYRFEFFRKMELFASWSDEKLWQLVAMAKIE 262
V E +DR F + +K + F + L S + ++V + +
Sbjct: 222 VATSEGSLWGLDRVTFRRIIVKNNAKKRKMFE-SFIESVPLLKSLEVSERMKIVDVIGEK 280
Query: 263 RFSYGQLISKDFGESPFIMFISKGSCEVL 291
+ G+ I ++ I G +L
Sbjct: 281 IYKDGERIITQGEKADSFYIIESGEVSIL 309
Score = 35.8 bits (81), Expect = 0.11
Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 143 IIKKGQKGNSFYFIYLGTVAI------TKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHAS 196
II +G+K +SFY I G V+I ++DG + + HKG FGE+ ++
Sbjct: 288 IITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQ--EVEIARCHKGQYFGELALVTNK 345
Query: 197 VRRSTIVCMEETEFLVVDREDF 218
R ++ + + + LV+D + F
Sbjct: 346 PRAASAYAVGDVKCLVMDVQAF 367
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 36.6 bits (83), Expect = 0.064
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 8/78 (10%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVL---HASVRR 199
+ KKG+ G Y I G V + DG S + L GS FGE+ +L + R
Sbjct: 989 VCKKGEIGREMYIIQAGQVQVLGGPDGKSVLV-----TLKAGSVFGEISLLAVGGGNRRT 1043
Query: 200 STIVCMEETEFLVVDRED 217
+ +V T ++D++D
Sbjct: 1044 ANVVAHGFTNLFILDKKD 1061
>gi|120433600 cyclic nucleotide gated channel alpha 3 isoform 2
[Homo sapiens]
Length = 676
Score = 32.7 bits (73), Expect = 0.92
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRS 200
I KKG G Y I G +A+ D DG + F+ +L GS FGE+ +L+ +S
Sbjct: 491 ICKKGDIGKEMYIINEGKLAVVAD-DGVTQFV-----VLSDGSYFGEISILNIKGSKS 542
>gi|4502917 cyclic nucleotide gated channel alpha 3 isoform 1 [Homo
sapiens]
Length = 694
Score = 32.7 bits (73), Expect = 0.92
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRS 200
I KKG G Y I G +A+ D DG + F+ +L GS FGE+ +L+ +S
Sbjct: 509 ICKKGDIGKEMYIINEGKLAVVAD-DGVTQFV-----VLSDGSYFGEISILNIKGSKS 560
>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
[Homo sapiens]
Length = 759
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 6/52 (11%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLH 194
I KKG G Y I G +A+ D DG + F+ +L GS FGE+ +L+
Sbjct: 575 ICKKGDIGREMYIIKEGKLAVVAD-DGVTQFV-----VLSDGSYFGEISILN 620
>gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [Homo
sapiens]
Length = 690
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 6/52 (11%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLH 194
I KKG G Y I G +A+ D DG + F+ +L GS FGE+ +L+
Sbjct: 506 ICKKGDIGREMYIIKEGKLAVVAD-DGVTQFV-----VLSDGSYFGEISILN 551
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 32.0 bits (71), Expect = 1.6
Identities = 53/215 (24%), Positives = 80/215 (37%), Gaps = 22/215 (10%)
Query: 340 PLQDFSSLKLPHLKKAWGLQGTSFSRKIRTSGDTLSKMLGPKIQSRPAQSIKCAMINIKP 399
PL S+K A+ +S S+K R+S + + P P S A ++ K
Sbjct: 346 PLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISP--VRLPLNSSLGAELSRKK 403
Query: 400 GELPKEAAVGAYVKVHTVEQGEILAFLPEGECDTRPLILMSLGNELIRIRKEIFYELIDN 459
E AA A K+ E FLP E + G E ++ + + E
Sbjct: 404 KE---RAAAAAAAKMDGKESKGSPVFLPRKE--NSSVEAKDSGLESKKLPRSVKLEKSAP 458
Query: 460 DDEMIKKLLKLNIAFPSDEDMCQKFLQQNSWNIFRKDLLQLLVEPCQSQLFTPNRP--KK 517
D E++ + LN + D + L +NS KDL ++Q ++P K
Sbjct: 459 DTELV-NVTHLNTEVKNSSDTGKVKLDENSEKHLVKDL--------KAQGTRDSKPIALK 509
Query: 518 REIYNPKSVVLDLCSINKTTKPRYPIFMAPQKYLP 552
EI PK + K T P P +P LP
Sbjct: 510 EEIVTPKETE----TSEKETPPPLPTIASPPPPLP 540
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 32.0 bits (71), Expect = 1.6
Identities = 53/215 (24%), Positives = 80/215 (37%), Gaps = 22/215 (10%)
Query: 340 PLQDFSSLKLPHLKKAWGLQGTSFSRKIRTSGDTLSKMLGPKIQSRPAQSIKCAMINIKP 399
PL S+K A+ +S S+K R+S + + P P S A ++ K
Sbjct: 346 PLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISP--VRLPLNSSLGAELSRKK 403
Query: 400 GELPKEAAVGAYVKVHTVEQGEILAFLPEGECDTRPLILMSLGNELIRIRKEIFYELIDN 459
E AA A K+ E FLP E + G E ++ + + E
Sbjct: 404 KE---RAAAAAAAKMDGKESKGSPVFLPRKE--NSSVEAKDSGLESKKLPRSVKLEKSAP 458
Query: 460 DDEMIKKLLKLNIAFPSDEDMCQKFLQQNSWNIFRKDLLQLLVEPCQSQLFTPNRP--KK 517
D E++ + LN + D + L +NS KDL ++Q ++P K
Sbjct: 459 DTELV-NVTHLNTEVKNSSDTGKVKLDENSEKHLVKDL--------KAQGTRDSKPIALK 509
Query: 518 REIYNPKSVVLDLCSINKTTKPRYPIFMAPQKYLP 552
EI PK + K T P P +P LP
Sbjct: 510 EEIVTPKETE----TSEKETPPPLPTIASPPPPLP 540
>gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens]
Length = 809
Score = 32.0 bits (71), Expect = 1.6
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 8/77 (10%)
Query: 143 IIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHA---SVRR 199
+ KKG+ G Y I G V + DG+ + L GS FGE+ +L A + R
Sbjct: 551 VCKKGEIGKEMYIIKHGEVQVLGGPDGTKVLV-----TLKAGSVFGEISLLAAGGGNRRT 605
Query: 200 STIVCMEETEFLVVDRE 216
+ +V L +D++
Sbjct: 606 ANVVAHGFANLLTLDKK 622
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 31.2 bits (69), Expect = 2.7
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 13/75 (17%)
Query: 132 MRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMD 191
+RFE F II++G G YFI G V++ + + D GS FGE+
Sbjct: 611 LRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKETKLAD--------GSYFGEIC 662
Query: 192 VL-----HASVRRST 201
+L ASVR T
Sbjct: 663 LLTRGRRTASVRADT 677
>gi|239753937 PREDICTED: similar to hCG2036828 [Homo sapiens]
Length = 275
Score = 31.2 bits (69), Expect = 2.7
Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 20/133 (15%)
Query: 103 EIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYLGTVA 162
+++ V + L +++ N E L+ + +R+ER V+ G +Y + G+V
Sbjct: 116 DLEIVYSYLHGMEALSNLREHQLRLMCETVRYERHEANEVLYYPDDIGTCWYILLSGSVF 175
Query: 163 ITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRS-TIVCMEETEFLVVDREDFFAN 221
I + S FL P+ S FG+ S RR + +E +E +VVD + +
Sbjct: 176 IKE-----SMFL---PR-----SSFGKRSA--GSFRRGCECIVLEPSEMIVVD----YMD 216
Query: 222 KLDQEVQKDAQYR 234
+ ++ Q+ A +R
Sbjct: 217 ENEEYFQRQASHR 229
>gi|112421013 signal-induced proliferation-associated 1 like 2 [Homo
sapiens]
Length = 1722
Score = 30.4 bits (67), Expect = 4.6
Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 178 PKLLHKGSCFGEMDVLHASVRRSTIV--CMEETEFLVVDREDFFANKL-DQEVQKDAQYR 234
P++ + EMDV+ + + T+V + ET+ V+ +EDF L D + ++ + +
Sbjct: 1412 PEVTECPGMYSEMDVMSTATQHQTVVGDAVAETQH-VLSKEDFLKLMLPDSPLVEEGRRK 1470
Query: 235 FEFFRKM----ELFASWSDEKL 252
F F+ + L+ + SDE +
Sbjct: 1471 FSFYGNLSPRRSLYRTLSDESI 1492
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,665,884
Number of Sequences: 37866
Number of extensions: 942937
Number of successful extensions: 2538
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2507
Number of HSP's gapped (non-prelim): 40
length of query: 572
length of database: 18,247,518
effective HSP length: 108
effective length of query: 464
effective length of database: 14,157,990
effective search space: 6569307360
effective search space used: 6569307360
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.