Guide to the Human Genome
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Search of human proteins with 18141316

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18141316 splA/ryanodine receptor domain and SOCS box
containing 1 [Homo sapiens]
         (273 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18141316 splA/ryanodine receptor domain and SOCS box containi...   570   e-163
gi|18254460 splA/ryanodine receptor domain and SOCS box containi...   434   e-122
gi|226423903 splA/ryanodine receptor domain and SOCS box contain...   258   3e-69
gi|14249178 splA/ryanodine receptor domain and SOCS box containi...   258   3e-69
gi|226423905 splA/ryanodine receptor domain and SOCS box contain...   221   4e-58
gi|157743247 F-box protein 45 [Homo sapiens]                          142   4e-34
gi|27552770 splA/ryanodine receptor domain and SOCS box containi...    61   1e-09
gi|18252778 ankyrin repeat and SOCS box-containing protein 2 [Ho...    41   0.001
gi|94721248 ankyrin repeat and SOCS box-containing protein 1 [Ho...    40   0.002
gi|37588869 ring finger protein 123 [Homo sapiens]                     40   0.002
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]       40   0.002
gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]    40   0.002
gi|18254474 ankyrin repeat and SOCS box-containing protein 11 is...    36   0.032
gi|60218887 ankyrin repeat and SOCS box-containing protein 11 is...    36   0.032
gi|38176283 ankyrin repeat and SOCS box-containing protein 7 iso...    34   0.12 
gi|22208951 ankyrin repeat and SOCS box-containing protein 3 iso...    34   0.16 
gi|7705831 ankyrin repeat and SOCS box-containing protein 3 isof...    34   0.16 
gi|13129098 ankyrin repeat and SOCS box-containing 8 [Homo sapiens]    33   0.35 
gi|218505706 ankyrin repeat and SOCS box-containing 14 isoform 1...    33   0.35 
gi|18390333 ankyrin repeat and SOCS box-containing 14 isoform 2 ...    33   0.35 
gi|134288906 tripartite motif-containing 67 [Homo sapiens]             32   0.46 
gi|18254476 ankyrin repeat and SOCS box-containing protein 5 [Ho...    32   0.46 
gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo sapi...    32   0.59 
gi|8923516 ankyrin repeat and SOCS box-containing 6 isoform 1 [H...    32   0.78 
gi|72534772 ankyrin repeat and SOCS box-containing 9 isoform 1 [...    31   1.0  
gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]     31   1.3  
gi|4507605 tumor necrosis factor ligand superfamily, member 7 [H...    30   1.7  
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso...    30   3.0  
gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso...    30   3.0  
gi|154354992 B-box and SPRY domain containing [Homo sapiens]           30   3.0  

>gi|18141316 splA/ryanodine receptor domain and SOCS box containing
           1 [Homo sapiens]
          Length = 273

 Score =  570 bits (1470), Expect = e-163
 Identities = 273/273 (100%), Positives = 273/273 (100%)

Query: 1   MGQKVTGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNND 60
           MGQKVTGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNND
Sbjct: 1   MGQKVTGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNND 60

Query: 61  RSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATA 120
           RSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATA
Sbjct: 61  RSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATA 120

Query: 121 DAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA 180
           DAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA
Sbjct: 121 DAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA 180

Query: 181 LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDL 240
           LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDL
Sbjct: 181 LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDL 240

Query: 241 CRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ 273
           CRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ
Sbjct: 241 CRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ 273


>gi|18254460 splA/ryanodine receptor domain and SOCS box containing
           4 [Homo sapiens]
          Length = 273

 Score =  434 bits (1117), Expect = e-122
 Identities = 204/273 (74%), Positives = 231/273 (84%)

Query: 1   MGQKVTGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNND 60
           MGQK++G +K+V++R+P  RP K+EL+G +  +P RLD LLDMP     VQL H+WN  D
Sbjct: 1   MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPED 60

Query: 61  RSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATA 120
           RSLNVFVK+DD+L FHRHPVAQSTD IRGKVG+ RGLH WQI W  RQRGTHAVVGVATA
Sbjct: 61  RSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATA 120

Query: 121 DAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA 180
            APLHSVGYT LVG++ ESWGWDLGR+RLYHDGKNQP   YPAFL PDE F +PDS LV 
Sbjct: 121 RAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVV 180

Query: 181 LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDL 240
           LDMD+GTLSFIVDGQY+GVAFRGLKGKKLYPVVSAVWGHCE+ MRY+NGLDPEPLPLMDL
Sbjct: 181 LDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDL 240

Query: 241 CRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ 273
           CRRS+R ALGR+RL +I +LPLP SLK YL YQ
Sbjct: 241 CRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273


>gi|226423903 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 1 [Homo sapiens]
          Length = 263

 Score =  258 bits (660), Expect = 3e-69
 Identities = 131/244 (53%), Positives = 159/244 (65%), Gaps = 2/244 (0%)

Query: 30  DYCKPTRLDLLLDMPPVSYDVQLLHSWNNNDRSLNVFVKEDDKLIFHRHPVAQSTDAIRG 89
           D   P  L+ LL  PP     Q  H WN  D S N+ VKE   L F R PVAQSTD  RG
Sbjct: 22  DLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGG-LYFERRPVAQSTDGARG 80

Query: 90  KVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDLGRNRL 149
           K GY+RGLH W+I+W + QRGTHAVVGVATA APL +  Y  L+G+N ESWGWD+GR +L
Sbjct: 81  KRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKL 140

Query: 150 YHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIVDGQYMGVAFRGLKGKKL 209
           YH  K   +  YPA  +  E   VP+  LV LDM++GTL + + G Y+G AFRGLKG+ L
Sbjct: 141 YHQSKGPGAPQYPAGTQ-GEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTL 199

Query: 210 YPVVSAVWGHCEIRMRYLNGLDPEPLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAY 269
           YP VSAVWG C++R+RYL     EP  L+ L R  VR  LG  RLG++  LPLP ++K Y
Sbjct: 200 YPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRY 259

Query: 270 LLYQ 273
           LLYQ
Sbjct: 260 LLYQ 263


>gi|14249178 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 1 [Homo sapiens]
          Length = 263

 Score =  258 bits (660), Expect = 3e-69
 Identities = 131/244 (53%), Positives = 159/244 (65%), Gaps = 2/244 (0%)

Query: 30  DYCKPTRLDLLLDMPPVSYDVQLLHSWNNNDRSLNVFVKEDDKLIFHRHPVAQSTDAIRG 89
           D   P  L+ LL  PP     Q  H WN  D S N+ VKE   L F R PVAQSTD  RG
Sbjct: 22  DLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGG-LYFERRPVAQSTDGARG 80

Query: 90  KVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDLGRNRL 149
           K GY+RGLH W+I+W + QRGTHAVVGVATA APL +  Y  L+G+N ESWGWD+GR +L
Sbjct: 81  KRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKL 140

Query: 150 YHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIVDGQYMGVAFRGLKGKKL 209
           YH  K   +  YPA  +  E   VP+  LV LDM++GTL + + G Y+G AFRGLKG+ L
Sbjct: 141 YHQSKGPGAPQYPAGTQ-GEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTL 199

Query: 210 YPVVSAVWGHCEIRMRYLNGLDPEPLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAY 269
           YP VSAVWG C++R+RYL     EP  L+ L R  VR  LG  RLG++  LPLP ++K Y
Sbjct: 200 YPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRY 259

Query: 270 LLYQ 273
           LLYQ
Sbjct: 260 LLYQ 263


>gi|226423905 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 2 [Homo sapiens]
          Length = 267

 Score =  221 bits (564), Expect = 4e-58
 Identities = 109/198 (55%), Positives = 132/198 (66%), Gaps = 2/198 (1%)

Query: 30  DYCKPTRLDLLLDMPPVSYDVQLLHSWNNNDRSLNVFVKEDDKLIFHRHPVAQSTDAIRG 89
           D   P  L+ LL  PP     Q  H WN  D S N+ VKE   L F R PVAQSTD  RG
Sbjct: 22  DLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGG-LYFERRPVAQSTDGARG 80

Query: 90  KVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDLGRNRL 149
           K GY+RGLH W+I+W + QRGTHAVVGVATA APL +  Y  L+G+N ESWGWD+GR +L
Sbjct: 81  KRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKL 140

Query: 150 YHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIVDGQYMGVAFRGLKGKKL 209
           YH  K   +  YPA  +  E   VP+  LV LDM++GTL + + G Y+G AFRGLKG+ L
Sbjct: 141 YHQSKGPGAPQYPAGTQ-GEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTL 199

Query: 210 YPVVSAVWGHCEIRMRYL 227
           YP VSAVWG C++R+RYL
Sbjct: 200 YPAVSAVWGQCQVRIRYL 217


>gi|157743247 F-box protein 45 [Homo sapiens]
          Length = 286

 Score =  142 bits (357), Expect = 4e-34
 Identities = 75/193 (38%), Positives = 120/193 (62%), Gaps = 6/193 (3%)

Query: 36  RLDLLLDMPPVSYDVQLL-HSWNNNDRSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYT 94
           R D+L ++P     ++   H+++ ND S NV++K++     HR+P+AQSTD  R K+G++
Sbjct: 93  RTDILCNLPSYKAKIRAFQHAFSTNDCSRNVYIKKNG-FTLHRNPIAQSTDGARTKIGFS 151

Query: 95  RGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGK 154
            G H W++ W     GT AV+G+AT  AP+   GY  L+G++ +SWGW+L  N L H+G 
Sbjct: 152 EGRHAWEVWWE-GPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNG- 209

Query: 155 NQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVS 214
            + + ++P      + + + +   V LDM+D TL+F    +++GVAFRGL    LYP VS
Sbjct: 210 -EVNGSFPQCNNAPK-YQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAVS 267

Query: 215 AVWGHCEIRMRYL 227
           AV+G+ E+ + YL
Sbjct: 268 AVYGNTEVTLVYL 280


>gi|27552770 splA/ryanodine receptor domain and SOCS box containing
           3 [Homo sapiens]
          Length = 355

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 57/217 (26%), Positives = 92/217 (42%), Gaps = 16/217 (7%)

Query: 56  WNNNDRSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVV 115
           W++ ++S    +  D++ +      +  T AIRG      G H W+I       GT  +V
Sbjct: 107 WDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMV 166

Query: 116 GVATADAPLHSVGYT--TLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIV 173
           G+ T+D  L    +T  +L+G + +SWG  L    L H   ++ S +          F  
Sbjct: 167 GIGTSDVDLDKYRHTFCSLLGRDEDSWG--LSYTGLLHHKGDKTSFS--------SRFGQ 216

Query: 174 PDSFLVALDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPE 233
                V LD   GTL+F  + + +GVA   L+ K+ YP+V +      ++   +      
Sbjct: 217 GSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMK---VTRSCAS 273

Query: 234 PLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAYL 270
              L  LC   +R  L  +    +  LPLP  LK  L
Sbjct: 274 ATSLQYLCCHRLR-QLRPDSGDTLEGLPLPPGLKQVL 309


>gi|18252778 ankyrin repeat and SOCS box-containing protein 2 [Homo
           sapiens]
          Length = 587

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 20/40 (50%), Positives = 25/40 (62%)

Query: 234 PLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ 273
           P PL  LCR  VR A+G+ R+  + TLPLP  L  YL Y+
Sbjct: 545 PRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYE 584


>gi|94721248 ankyrin repeat and SOCS box-containing protein 1 [Homo
           sapiens]
          Length = 335

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 20/40 (50%), Positives = 28/40 (70%)

Query: 234 PLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ 273
           P  L+ LCR +VR ALG+ RL  I +LPLP  +K +LL++
Sbjct: 296 PRTLLCLCRVAVRRALGKHRLHLIPSLPLPDPIKKFLLHE 335


>gi|37588869 ring finger protein 123 [Homo sapiens]
          Length = 1314

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 13/85 (15%)

Query: 133 VGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIV 192
           VG+ H S+ +D  R R ++       K + A           D     +D+DDGTLSF +
Sbjct: 164 VGDTHNSYAYDGNRVRKWNVTTTNYGKAWAA----------GDIVSCLIDLDDGTLSFCL 213

Query: 193 DGQYMGVAFRGLK---GKKLYPVVS 214
           +G  +G AF  L    G   +P +S
Sbjct: 214 NGVSLGTAFENLSRGLGMAYFPAIS 238


>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
          Length = 710

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 30/129 (23%), Positives = 56/129 (43%), Gaps = 13/129 (10%)

Query: 87  IRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDLGR 146
           + GK G+++G+H W++T            GVA  D     V    ++G + ++W   +  
Sbjct: 568 VLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARMD-----VMKDVMLGKDDKAWAMYVDN 622

Query: 147 NRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIVDGQYMG-VAFRGLK 205
           NR +    N  +      +    T        V LD++   L+F ++ +  G +AF  ++
Sbjct: 623 NRSWFMHNNSHTNRTEGGITKGAT------IGVLLDLNRKNLTFFINDEQQGPIAFDNVE 676

Query: 206 GKKLYPVVS 214
           G   +P VS
Sbjct: 677 G-LFFPAVS 684


>gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]
          Length = 4861

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 14/122 (11%)

Query: 92   GYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDLGRNRLYH 151
            G T G + W+       RG      V  +  P+H   + T      + W +      LYH
Sbjct: 2066 GVTSGCYQWKFYIVKENRGNEGTC-VGVSRWPVHDFNHRT----TSDMWLYRAYSGNLYH 2120

Query: 152  DGKNQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIVDGQYMGVAFRGLKGKKLYP 211
            +G+   + T  +F + D  FI        LDM+  T+SF  +G+   +AF  +   +LYP
Sbjct: 2121 NGEQ--TLTLSSFTQGD--FIT-----CVLDMEARTISFGKNGEEPKLAFEDVDAAELYP 2171

Query: 212  VV 213
             V
Sbjct: 2172 CV 2173


>gi|18254474 ankyrin repeat and SOCS box-containing protein 11
           isoform a [Homo sapiens]
          Length = 323

 Score = 36.2 bits (82), Expect = 0.032
 Identities = 20/40 (50%), Positives = 22/40 (55%)

Query: 234 PLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ 273
           P  L  LCR  VR  LGR     IH L LP  L+ +LLYQ
Sbjct: 284 PPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLYQ 323


>gi|60218887 ankyrin repeat and SOCS box-containing protein 11
           isoform b [Homo sapiens]
          Length = 302

 Score = 36.2 bits (82), Expect = 0.032
 Identities = 20/40 (50%), Positives = 22/40 (55%)

Query: 234 PLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ 273
           P  L  LCR  VR  LGR     IH L LP  L+ +LLYQ
Sbjct: 263 PPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLYQ 302


>gi|38176283 ankyrin repeat and SOCS box-containing protein 7
           isoform 2 [Homo sapiens]
          Length = 318

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 19/72 (26%), Positives = 35/72 (48%)

Query: 202 RGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDLCRRSVRLALGRERLGEIHTLP 261
           R  +G+    V  ++ G     + +L  +  +P  L DLCR  +R  +G + L  +  LP
Sbjct: 243 RNYEGQTPLAVSISISGSSRPCLDFLQEVTRQPRNLQDLCRIKIRQCIGLQNLKLLDELP 302

Query: 262 LPASLKAYLLYQ 273
           +   +K YL ++
Sbjct: 303 IAKVMKDYLKHK 314


>gi|22208951 ankyrin repeat and SOCS box-containing protein 3
           isoform b [Homo sapiens]
          Length = 445

 Score = 33.9 bits (76), Expect = 0.16
 Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 3/40 (7%)

Query: 237 LMDLCRRSVRLALGRERLGE---IHTLPLPASLKAYLLYQ 273
           L  LCR  +R +L  ERL     I  LPLP SL  YLLY+
Sbjct: 389 LTHLCRLEIRSSLKSERLRSDSYISQLPLPRSLHNYLLYE 428


>gi|7705831 ankyrin repeat and SOCS box-containing protein 3 isoform
           a [Homo sapiens]
          Length = 518

 Score = 33.9 bits (76), Expect = 0.16
 Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 3/40 (7%)

Query: 237 LMDLCRRSVRLALGRERLGE---IHTLPLPASLKAYLLYQ 273
           L  LCR  +R +L  ERL     I  LPLP SL  YLLY+
Sbjct: 462 LTHLCRLEIRSSLKSERLRSDSYISQLPLPRSLHNYLLYE 501


>gi|13129098 ankyrin repeat and SOCS box-containing 8 [Homo sapiens]
          Length = 288

 Score = 32.7 bits (73), Expect = 0.35
 Identities = 20/39 (51%), Positives = 25/39 (64%), Gaps = 1/39 (2%)

Query: 234 PLPLMDLCRRSVRLALGRERLGE-IHTLPLPASLKAYLL 271
           P  L  L R +VR +LG + L + +  LPLPASLK YLL
Sbjct: 247 PGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLL 285


>gi|218505706 ankyrin repeat and SOCS box-containing 14 isoform 1
           [Homo sapiens]
          Length = 423

 Score = 32.7 bits (73), Expect = 0.35
 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 3/43 (6%)

Query: 234 PLPLMDLCRRSVRLALGRERLG---EIHTLPLPASLKAYLLYQ 273
           P  L  LCR  +R  +GR  L     +  LPLP  LKAY+LY+
Sbjct: 367 PRSLKHLCRLKIRKCMGRLHLRCPVFMSFLPLPNRLKAYVLYK 409


>gi|18390333 ankyrin repeat and SOCS box-containing 14 isoform 2
           [Homo sapiens]
          Length = 302

 Score = 32.7 bits (73), Expect = 0.35
 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 3/43 (6%)

Query: 234 PLPLMDLCRRSVRLALGRERLG---EIHTLPLPASLKAYLLYQ 273
           P  L  LCR  +R  +GR  L     +  LPLP  LKAY+LY+
Sbjct: 246 PRSLKHLCRLKIRKCMGRLHLRCPVFMSFLPLPNRLKAYVLYK 288


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score = 32.3 bits (72), Expect = 0.46
 Identities = 28/121 (23%), Positives = 50/121 (41%), Gaps = 12/121 (9%)

Query: 87  IRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDLGR 146
           + G   +++G+H W++             GVA A     SV    ++G + ++W   +  
Sbjct: 640 VLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARA-----SVVKDMMLGKDDKAWAMYVDN 694

Query: 147 NRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIVDGQYMG-VAFRGLK 205
           NR +    N  +      +    T  V       LD++  TL+F ++GQ  G  AF  + 
Sbjct: 695 NRSWFMHCNSHTNRTEGGVCKGATVGV------LLDLNKHTLTFFINGQQQGPTAFSHVD 748

Query: 206 G 206
           G
Sbjct: 749 G 749


>gi|18254476 ankyrin repeat and SOCS box-containing protein 5 [Homo
           sapiens]
          Length = 329

 Score = 32.3 bits (72), Expect = 0.46
 Identities = 17/40 (42%), Positives = 22/40 (55%)

Query: 234 PLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ 273
           P  L  LCR  +R  +G+ RL  I  L LP  LK +L Y+
Sbjct: 290 PSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR 329


>gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo
           sapiens]
          Length = 588

 Score = 32.0 bits (71), Expect = 0.59
 Identities = 14/43 (32%), Positives = 25/43 (58%), Gaps = 3/43 (6%)

Query: 234 PLPLMDLCRRSVRLALGRERL---GEIHTLPLPASLKAYLLYQ 273
           P  L  LCR  +R  +G ++L     +  LPLP +++ Y+L++
Sbjct: 534 PCSLKHLCRLKIRRLMGLQKLCQPASVEKLPLPPAIQRYILFK 576


>gi|8923516 ankyrin repeat and SOCS box-containing 6 isoform 1 [Homo
           sapiens]
          Length = 421

 Score = 31.6 bits (70), Expect = 0.78
 Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 1/46 (2%)

Query: 227 LNGLDPEPLPLMDLCRRSVRLALGRERLG-EIHTLPLPASLKAYLL 271
           L  L+  P PL  LCR ++RL L    +  ++  LPLP  LK YLL
Sbjct: 365 LRQLESYPPPLKHLCRVAIRLYLQPWPVDVKVKALPLPDRLKWYLL 410


>gi|72534772 ankyrin repeat and SOCS box-containing 9 isoform 1
           [Homo sapiens]
          Length = 294

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 16/39 (41%), Positives = 22/39 (56%)

Query: 234 PLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAYLLY 272
           P  LM LCR  +R   G ++  +I  L LP  LK +LL+
Sbjct: 255 PPSLMQLCRLRIRKCFGIQQHHKITKLVLPEDLKQFLLH 293


>gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]
          Length = 740

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 28/116 (24%), Positives = 55/116 (47%), Gaps = 16/116 (13%)

Query: 117 VATADAPLHSVGYTTLVGN---NHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIV 173
           V+  D  L  VG++T+  +     + +G+  G       GK   +K +  +    E F +
Sbjct: 137 VSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGT-----GKKSHNKQFDNY---GEEFTM 188

Query: 174 PDSFLVALDMDDGTLSFIVDGQYMGVAFR---GLKGKKLYPVVSAVWGHCEIRMRY 226
            D+    LD+D G + F  +G+ +G+AF     +K + L+P  + V  + E++  +
Sbjct: 189 HDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFP--ACVLKNAELKFNF 242


>gi|4507605 tumor necrosis factor ligand superfamily, member 7 [Homo
           sapiens]
          Length = 193

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 13/64 (20%)

Query: 138 ESWGWDLGRNRLYHDGKNQPSKTY----PAFLEPDETFIVPDSFLVALDMDDGTLSFIVD 193
           ES GWD+   +L H G  Q  + Y    PA         +  SFL   ++D G L    D
Sbjct: 51  ESLGWDVAELQLNHTGPQQDPRLYWQGGPA---------LGRSFLHGPELDKGQLRIHRD 101

Query: 194 GQYM 197
           G YM
Sbjct: 102 GIYM 105


>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
           isoform d [Homo sapiens]
          Length = 756

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 16/34 (47%), Positives = 22/34 (64%), Gaps = 4/34 (11%)

Query: 184 DDGTLSFIVDGQYMGVAFR----GLKGKKLYPVV 213
           +D  LSF  +G++MG+AFR     L G+ LYP V
Sbjct: 239 NDVELSFTKNGKWMGIAFRIQKEALGGQALYPHV 272


>gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1
           isoform a [Homo sapiens]
          Length = 856

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 16/34 (47%), Positives = 22/34 (64%), Gaps = 4/34 (11%)

Query: 184 DDGTLSFIVDGQYMGVAFR----GLKGKKLYPVV 213
           +D  LSF  +G++MG+AFR     L G+ LYP V
Sbjct: 339 NDVELSFTKNGKWMGIAFRIQKEALGGQALYPHV 372


>gi|154354992 B-box and SPRY domain containing [Homo sapiens]
          Length = 402

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 5/67 (7%)

Query: 93  YTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDL--GRNRLY 150
           +  GLH W +     Q      VGVA+   P    G    +G+N  SW +       R  
Sbjct: 281 FQNGLHAWMVNV---QNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFS 337

Query: 151 HDGKNQP 157
           H+G+++P
Sbjct: 338 HNGQHEP 344


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,158,986
Number of Sequences: 37866
Number of extensions: 505219
Number of successful extensions: 835
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 798
Number of HSP's gapped (non-prelim): 40
length of query: 273
length of database: 18,247,518
effective HSP length: 101
effective length of query: 172
effective length of database: 14,423,052
effective search space: 2480764944
effective search space used: 2480764944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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