Search of human proteins with 18104952

Search of human proteins with 18104952

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18104952 T-box 1 isoform C [Homo sapiens]
         (495 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18104952 T-box 1 isoform C [Homo sapiens]                         1040   0.0  
gi|18104950 T-box 1 isoform A [Homo sapiens]                          706   0.0  
gi|5174711 T-box 1 isoform B [Homo sapiens]                           702   0.0  
gi|32567784 T-box 10 [Homo sapiens]                                   388   e-108
gi|18129690 T-box 4 [Homo sapiens]                                    260   2e-69
gi|117676399 T-box transcription factor TBX20 [Homo sapiens]          256   3e-68
gi|197333868 T-box 2 [Homo sapiens]                                   249   5e-66
gi|122937456 T-box 18 [Homo sapiens]                                  245   8e-65
gi|55770860 T-box 15 [Homo sapiens]                                   242   5e-64
gi|18201896 T-box 5 isoform 2 [Homo sapiens]                          241   1e-63
gi|18201892 T-box 5 isoform 1 [Homo sapiens]                          241   1e-63
gi|31652232 T-box 5 isoform 1 [Homo sapiens]                          241   1e-63
gi|18201894 T-box 5 isoform 3 [Homo sapiens]                          238   9e-63
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]                  232   5e-61
gi|18201900 T-box 6 [Homo sapiens]                                    231   1e-60
gi|158187509 T-box 22 isoform 1 [Homo sapiens]                        223   2e-58
gi|18375603 T-box 22 isoform 1 [Homo sapiens]                         223   2e-58
gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]                  221   2e-57
gi|7019549 T-box 21 [Homo sapiens]                                    197   2e-50
gi|122937388 MAX gene associated [Homo sapiens]                       196   5e-50
gi|158187511 T-box 22 isoform 2 [Homo sapiens]                        186   3e-47
gi|22538470 eomesodermin [Homo sapiens]                               184   2e-46
gi|5730081 T-box, brain, 1 [Homo sapiens]                             174   1e-43
gi|4507339 transcription factor T [Homo sapiens]                      172   6e-43
gi|4827024 T-box 19 [Homo sapiens]                                    169   4e-42
gi|239755362 PREDICTED: hypothetical protein [Homo sapiens]            74   2e-13
gi|89257348 homeo box HB9 [Homo sapiens]                               54   2e-07
gi|18959212 GS homeobox 2 [Homo sapiens]                               52   1e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    50   5e-06
gi|39812378 RAN binding protein 9 [Homo sapiens]                       49   8e-06

>gi|18104952 T-box 1 isoform C [Homo sapiens]
          Length = 495

 Score = 1040 bits (2689), Expect = 0.0
 Identities = 495/495 (100%), Positives = 495/495 (100%)

Query: 1   MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60
           MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA
Sbjct: 1   MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60

Query: 61  PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120
           PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW
Sbjct: 61  PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120

Query: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180
           DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL
Sbjct: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180

Query: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240
           VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR
Sbjct: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240

Query: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300
           FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP
Sbjct: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300

Query: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKDAAEARREFQRDAGGPAVLGDPAH 360
           EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKDAAEARREFQRDAGGPAVLGDPAH
Sbjct: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKDAAEARREFQRDAGGPAVLGDPAH 360

Query: 361 PPQLLARVLSPSLPGAGGAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPLHHHPYKYPA 420
           PPQLLARVLSPSLPGAGGAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPLHHHPYKYPA
Sbjct: 361 PPQLLARVLSPSLPGAGGAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPLHHHPYKYPA 420

Query: 421 AAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAANMYS 480
           AAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAANMYS
Sbjct: 421 AAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAANMYS 480

Query: 481 SAGAAPPGSYDYCPR 495
           SAGAAPPGSYDYCPR
Sbjct: 481 SAGAAPPGSYDYCPR 495


>gi|18104950 T-box 1 isoform A [Homo sapiens]
          Length = 398

 Score =  706 bits (1821), Expect = 0.0
 Identities = 346/374 (92%), Positives = 347/374 (92%), Gaps = 16/374 (4%)

Query: 1   MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60
           MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA
Sbjct: 1   MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60

Query: 61  PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120
           PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW
Sbjct: 61  PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120

Query: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180
           DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL
Sbjct: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180

Query: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240
           VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR
Sbjct: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240

Query: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300
           FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP
Sbjct: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300

Query: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEK----------------DAAEARRE 344
           EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEK                +  E   E
Sbjct: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGGHVLKDKEVKAETSRNTPEREVE 360

Query: 345 FQRDAGGPAVLGDP 358
             RDAGG   LG P
Sbjct: 361 LLRDAGGCVNLGLP 374



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 35/116 (30%), Positives = 40/116 (34%), Gaps = 32/116 (27%)

Query: 372 SLPGAGGAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPLHHHPYKYPAAAYDHYLGAKS 431
           SL   G AGG  P   +PG  P  P            EP    P   P AA      A  
Sbjct: 17  SLSSLGAAGGF-PGAASPGADPYGPR-----------EPPPPPPRYDPCAA-----AAPG 59

Query: 432 RPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAANMYSSAGAAPP 487
            P P P P               H +P +PAA AA +AAA         +A A  P
Sbjct: 60  APGPPPPP---------------HAYPFAPAAGAATSAAAEPEGPGASCAAAAKAP 100


>gi|5174711 T-box 1 isoform B [Homo sapiens]
          Length = 372

 Score =  702 bits (1812), Expect = 0.0
 Identities = 343/371 (92%), Positives = 345/371 (92%), Gaps = 5/371 (1%)

Query: 1   MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60
           MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA
Sbjct: 1   MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60

Query: 61  PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120
           PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW
Sbjct: 61  PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120

Query: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180
           DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL
Sbjct: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180

Query: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240
           VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR
Sbjct: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240

Query: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300
           FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP
Sbjct: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300

Query: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKDAAEARREFQRDAGGPAVLGDPAH 360
           EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEK         Q     P +L     
Sbjct: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVTEGSGLQ-----PGLLDVLLK 355

Query: 361 PPQLLARVLSP 371
           PP   +  L P
Sbjct: 356 PPSKKSESLRP 366



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 35/116 (30%), Positives = 40/116 (34%), Gaps = 32/116 (27%)

Query: 372 SLPGAGGAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPLHHHPYKYPAAAYDHYLGAKS 431
           SL   G AGG  P   +PG  P  P            EP    P   P AA      A  
Sbjct: 17  SLSSLGAAGGF-PGAASPGADPYGPR-----------EPPPPPPRYDPCAA-----AAPG 59

Query: 432 RPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAANMYSSAGAAPP 487
            P P P P               H +P +PAA AA +AAA         +A A  P
Sbjct: 60  APGPPPPP---------------HAYPFAPAAGAATSAAAEPEGPGASCAAAAKAP 100


>gi|32567784 T-box 10 [Homo sapiens]
          Length = 385

 Score =  388 bits (997), Expect = e-108
 Identities = 213/381 (55%), Positives = 249/381 (65%), Gaps = 47/381 (12%)

Query: 64  PPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEF 123
           P P  +  + P  G+   +       GA   A       KN +V+ V+VQLEMK LW+EF
Sbjct: 19  PLPTTSSGWEPRLGSPFPSGPCTSSTGAQAVAEPTGQGPKNPRVSRVTVQLEMKPLWEEF 78

Query: 124 NQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAG 183
           NQLGTEMIVTKAGRRMFP FQVK+ GMD +ADY LLMDF+P+DDKRYRYAFHSS+WLVAG
Sbjct: 79  NQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAG 138

Query: 184 KADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHV 243
           KADPATPGRVH+HPDSPAKGAQWM+QIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHV
Sbjct: 139 KADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHV 198

Query: 244 VYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDW 303
           V+VDPRKDSE+YA+ENFK+F+F ET+FTAVTAYQNHRITQLKIASNPFAKGFR+ D + W
Sbjct: 199 VFVDPRKDSERYAQENFKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRESDLDSW 258

Query: 304 PRNHRPGALPLMSAFARSRNPVASPTQPSGT--EKDAAEARREFQRDAGGPAVLGDPAHP 361
           P   RP    L+S  ARS + ++       T  EKD  +A     +    PA L     P
Sbjct: 259 PVAPRP----LLSVPARSHSSLSPCVLKGATDREKDPNKASASTSKT---PAWLHHQLLP 311

Query: 362 PQLLARVLSPSLPGAGGAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPLHHHPYKYPAA 421
           P                                   PE+ L AP    P+ +      + 
Sbjct: 312 P-----------------------------------PEVLL-APATYRPVTYQSLY--SG 333

Query: 422 AYDHYLGAKSRPAPYPLPGLR 442
           A  H    ++RPAPYPLP +R
Sbjct: 334 APSHLGIPRTRPAPYPLPNIR 354


>gi|18129690 T-box 4 [Homo sapiens]
          Length = 545

 Score =  260 bits (664), Expect = 2e-69
 Identities = 147/314 (46%), Positives = 193/314 (61%), Gaps = 20/314 (6%)

Query: 60  APGPPPPPHAYPFAP-----AAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQL 114
           APGP     +   AP     A G + +A   P GPGA   AAA A       +  + V L
Sbjct: 16  APGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAAAAA----EQTIENIKVGL 71

Query: 115 EMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAF 174
             K LW +F++ GTEMI+TKAGRRMFP+++VK+ GM+P   Y+LL+D VP DD RY++  
Sbjct: 72  HEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFC- 130

Query: 175 HSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSM 234
             + W+VAGKA+PA PGR++ HPDSPA GA WM+Q+VSF KLKLTNN LD  GHIILNSM
Sbjct: 131 -DNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSM 189

Query: 235 HRYQPRFHVVYVDPRKDSEKYAEEN--FKTFVFEETRFTAVTAYQNHRITQLKIASNPFA 292
           H+YQPR H+V  D   ++  +  +N  F T VF ET F +VT+YQNH+ITQLKI +NPFA
Sbjct: 190 HKYQPRLHIVKAD---ENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFA 246

Query: 293 KGFRDCDPEDW-PRNHRPGALPLMS-AFARSR--NPVASPTQPSGTEKDAAEARREFQRD 348
           KGFR  D  D      +    P++S +  R R  +P  S T   G      +A + +Q +
Sbjct: 247 KGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLGTHQALQHYQHE 306

Query: 349 AGGPAVLGDPAHPP 362
            G  + L +P   P
Sbjct: 307 NGAHSQLAEPQDLP 320


>gi|117676399 T-box transcription factor TBX20 [Homo sapiens]
          Length = 447

 Score =  256 bits (655), Expect = 3e-68
 Identities = 131/237 (55%), Positives = 165/237 (69%), Gaps = 12/237 (5%)

Query: 73  APAAGAATSAAAEPEGPGASCAAAAKA-----------PVKKNAKVAGVSVQLEMKALWD 121
           A   G  TS  A  E  G S ++ + +           P+  + ++A ++  LE K LWD
Sbjct: 52  AQPLGELTSLDAHGEFGGGSGSSPSSSSLCTEPLIPTTPIIPSEEMAKIACSLETKELWD 111

Query: 122 EFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLV 181
           +F++LGTEMI+TK+GRRMFPT +V   G+DP A Y++LMD VPVD+KRYRYA+H SSWLV
Sbjct: 112 KFHELGTEMIITKSGRRMFPTIRVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLV 171

Query: 182 AGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRF 241
           AGKADP  P R++ HPDSP  G Q +KQ+VSF+K+KLTNN LD +GHIILNSMH+YQPR 
Sbjct: 172 AGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRV 231

Query: 242 HVV-YVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
           H++   D          E F+TF+F ET FTAVTAYQN  IT+LKI SNPFAKGFRD
Sbjct: 232 HIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRD 288


>gi|197333868 T-box 2 [Homo sapiens]
          Length = 712

 Score =  249 bits (635), Expect = 5e-66
 Identities = 134/258 (51%), Positives = 168/258 (65%), Gaps = 13/258 (5%)

Query: 48  PRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEP--------EGPGASCAAAAKA 99
           P + P  A  PGA   P P      A AA AA +AAAE           P A+   + K+
Sbjct: 35  PSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKS 94

Query: 100 PVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLL 159
              ++       V LE K LWD+F++LGTEM++TK+GRRMFP F+V++ G+D  A Y+LL
Sbjct: 95  LEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILL 154

Query: 160 MDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLT 219
           MD V  DD RY+  FH+S W+VAGKADP  P R++ HPDSPA G QWM + V+F KLKLT
Sbjct: 155 MDIVAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLT 212

Query: 220 NNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNH 279
           NN+ D +G  ILNSMH+YQPRFH+V  +   D  K     F+T+VF ET F AVTAYQN 
Sbjct: 213 NNISDKHGFTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYVFPETDFIAVTAYQND 269

Query: 280 RITQLKIASNPFAKGFRD 297
           +ITQLKI +NPFAKGFRD
Sbjct: 270 KITQLKIDNNPFAKGFRD 287



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 34/100 (34%)

Query: 407 ASEPLHHHPYKYP-----------AAAYDHYLGAKSRPA-----PYPLPGLRGHGYHPHA 450
           A+  + +HP+  P           AAA   +  A + P      P P PGL G       
Sbjct: 7   AASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAG------- 59

Query: 451 HPHHHHHPVSPAAAAAAAAAAAAAAANMYSSAGAAPPGSY 490
                      AAAAAAAAAAAA A    S+ G  PP ++
Sbjct: 60  -----------AAAAAAAAAAAAEAGLHVSALGPHPPAAH 88



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 18/146 (12%)

Query: 351 GPAVLGDPA--HPPQLLARVLSPSLPGAGGAGGLVP-LPGAPGGRPSPPNPELRLEA--- 404
           GP   G P   HP Q     + P    A G G L+  + G   G    P     L+A   
Sbjct: 481 GPLGAGQPLFLHPGQF---TMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGL 537

Query: 405 -PGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHHHHHPVS--P 461
            P AS      P+ +  +   H L ++      P+P   G   +P+ +        S  P
Sbjct: 538 GPAASAASTAAPFPFHLS--QHMLASQG----IPMPTFGGLFPYPYTYMAAAAAAASALP 591

Query: 462 AAAAAAAAAAAAAAANMYSSAGAAPP 487
           A +AAAAAAAAA + +     G+A P
Sbjct: 592 ATSAAAAAAAAAGSLSRSPFLGSARP 617



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 35/119 (29%), Positives = 47/119 (39%), Gaps = 15/119 (12%)

Query: 1   MHFSTVTRDMEAFTASSLSSLGAA--------GGFPG-AASPGADPYGPREPP-----PP 46
           +H    T    AF+A  +  L A+        GG PG AA   A   GP         P 
Sbjct: 491 LHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAPF 550

Query: 47  PPRYDPCAAAAPGAPGPP-PPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN 104
           P        A+ G P P       YP+   A AA +A+A P    A+ AAAA   + ++
Sbjct: 551 PFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRS 609


>gi|122937456 T-box 18 [Homo sapiens]
          Length = 607

 Score =  245 bits (625), Expect = 8e-65
 Identities = 135/280 (48%), Positives = 160/280 (57%), Gaps = 14/280 (5%)

Query: 25  GGFPGAASPGADPYGPREPPPPPPRYDPCAAAAP---GAPGPPPPPHAYPFAPAAGAATS 81
           GG  G         G   PPP      P  + A    GA G         F   A    S
Sbjct: 58  GGGAGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDG----FQQGASPLAS 113

Query: 82  AAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFP 141
               P+G  A   A    P+          V L+   LW  F+++GTEMI+TKAGRRMFP
Sbjct: 114 PGGSPKGSPARSLARPGTPLPSPQ---APRVDLQGAELWKRFHEIGTEMIITKAGRRMFP 170

Query: 142 TFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPA 201
             +VK+ G+DP   Y + MD VPVD+KRYRY +HSS W+VAG AD   P RV+ HPDSPA
Sbjct: 171 AMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPA 230

Query: 202 KGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKY----AE 257
            G  WM+Q++SFDKLKLTNN LDD GHIIL+SMH+YQPR HV+  D   D        + 
Sbjct: 231 SGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSG 290

Query: 258 ENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
           E  K F F ET FT VTAYQN +IT+LKI  NPFAKGFRD
Sbjct: 291 EGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRD 330


>gi|55770860 T-box 15 [Homo sapiens]
          Length = 496

 Score =  242 bits (618), Expect = 5e-64
 Identities = 133/272 (48%), Positives = 162/272 (59%), Gaps = 24/272 (8%)

Query: 110 VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 169
           + V+L+   LW  F+ +GTEMI+TKAGRRMFP  +VK+ G+DP   Y + MD VPVD+KR
Sbjct: 7   IQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKR 66

Query: 170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI 229
           YRY +HSS W+VAG AD   P RV+ HPDS A G  WM+Q+VSFDKLKLTNN LDD GHI
Sbjct: 67  YRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHI 126

Query: 230 ILNSMHRYQPRFHVVYVDPRKDSEKY----AEENFKTFVFEETRFTAVTAYQNHRITQLK 285
           IL+SMH+YQPR HV+  D   D          +  KTF F ET FT VTAYQN +IT+LK
Sbjct: 127 ILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLK 186

Query: 286 IASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKDAAEARREF 345
           I  NPFAKGFRD         +R G   +M  +A  R PV + T    T           
Sbjct: 187 IDRNPFAKGFRDSG------RNRTGLEAIMETYAFWRPPVRTLTFEDFT---------TM 231

Query: 346 QRDAGG-----PAVLGDPAHPPQLLARVLSPS 372
           Q+  GG     P         P   + +LSPS
Sbjct: 232 QKQQGGSTGTSPTTSSTGTPSPSASSHLLSPS 263


>gi|18201896 T-box 5 isoform 2 [Homo sapiens]
          Length = 349

 Score =  241 bits (614), Expect = 1e-63
 Identities = 130/259 (50%), Positives = 172/259 (66%), Gaps = 15/259 (5%)

Query: 89  PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143
           P ++  A +K+P    A      + G+ V L  + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 28  PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87

Query: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203
           +VK+ G++P   Y+LLMD VP DD RY++A   + W V GKA+PA PGR++ HPDSPA G
Sbjct: 88  KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145

Query: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261
           A WM+Q+VSF KLKLTNN LD  GHIILNSMH+YQPR H+V  D   ++  +  +N  F 
Sbjct: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202

Query: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFA 319
           T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR  D  +  R  R  +   P++   +
Sbjct: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-S 261

Query: 320 RSRNPVASPTQPSGTEKDA 338
             R  VAS   P  +E  A
Sbjct: 262 TVRQKVASNHSPFSSESRA 280


>gi|18201892 T-box 5 isoform 1 [Homo sapiens]
          Length = 518

 Score =  241 bits (614), Expect = 1e-63
 Identities = 130/259 (50%), Positives = 172/259 (66%), Gaps = 15/259 (5%)

Query: 89  PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143
           P ++  A +K+P    A      + G+ V L  + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 28  PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87

Query: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203
           +VK+ G++P   Y+LLMD VP DD RY++A   + W V GKA+PA PGR++ HPDSPA G
Sbjct: 88  KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145

Query: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261
           A WM+Q+VSF KLKLTNN LD  GHIILNSMH+YQPR H+V  D   ++  +  +N  F 
Sbjct: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202

Query: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFA 319
           T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR  D  +  R  R  +   P++   +
Sbjct: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-S 261

Query: 320 RSRNPVASPTQPSGTEKDA 338
             R  VAS   P  +E  A
Sbjct: 262 TVRQKVASNHSPFSSESRA 280


>gi|31652232 T-box 5 isoform 1 [Homo sapiens]
          Length = 518

 Score =  241 bits (614), Expect = 1e-63
 Identities = 130/259 (50%), Positives = 172/259 (66%), Gaps = 15/259 (5%)

Query: 89  PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143
           P ++  A +K+P    A      + G+ V L  + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 28  PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87

Query: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203
           +VK+ G++P   Y+LLMD VP DD RY++A   + W V GKA+PA PGR++ HPDSPA G
Sbjct: 88  KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145

Query: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261
           A WM+Q+VSF KLKLTNN LD  GHIILNSMH+YQPR H+V  D   ++  +  +N  F 
Sbjct: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202

Query: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFA 319
           T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR  D  +  R  R  +   P++   +
Sbjct: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-S 261

Query: 320 RSRNPVASPTQPSGTEKDA 338
             R  VAS   P  +E  A
Sbjct: 262 TVRQKVASNHSPFSSESRA 280


>gi|18201894 T-box 5 isoform 3 [Homo sapiens]
          Length = 468

 Score =  238 bits (607), Expect = 9e-63
 Identities = 125/234 (53%), Positives = 162/234 (69%), Gaps = 10/234 (4%)

Query: 109 GVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDK 168
           G+ V L  + LW +F+++GTEMI+TKAGRRMFP+++VK+ G++P   Y+LLMD VP DD 
Sbjct: 3   GIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDH 62

Query: 169 RYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH 228
           RY++A   + W V GKA+PA PGR++ HPDSPA GA WM+Q+VSF KLKLTNN LD  GH
Sbjct: 63  RYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120

Query: 229 IILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FKTFVFEETRFTAVTAYQNHRITQLKI 286
           IILNSMH+YQPR H+V  D   ++  +  +N  F T VF ET F AVT+YQNH+ITQLKI
Sbjct: 121 IILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKI 177

Query: 287 ASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFARSRNPVASPTQPSGTEKDA 338
            +NPFAKGFR  D  +  R  R  +   P++   +  R  VAS   P  +E  A
Sbjct: 178 ENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-STVRQKVASNHSPFSSESRA 230


>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
          Length = 723

 Score =  232 bits (592), Expect = 5e-61
 Identities = 111/186 (59%), Positives = 140/186 (75%), Gaps = 5/186 (2%)

Query: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171
           V LE K LWD+F++ GTEM++TK+GRRMFP F+V+  G+D  A Y+LLMD +  DD RY+
Sbjct: 105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK 164

Query: 172 YAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIIL 231
             FH+S W+VAGKADP  P R++ HPDSPA G QWM ++V+F KLKLTNN+ D +G  IL
Sbjct: 165 --FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTIL 222

Query: 232 NSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPF 291
           NSMH+YQPRFH+V  +   D  K     F+T++F ET F AVTAYQN +ITQLKI +NPF
Sbjct: 223 NSMHKYQPRFHIVRAN---DILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPF 279

Query: 292 AKGFRD 297
           AKGFRD
Sbjct: 280 AKGFRD 285


>gi|18201900 T-box 6 [Homo sapiens]
          Length = 436

 Score =  231 bits (588), Expect = 1e-60
 Identities = 172/454 (37%), Positives = 216/454 (47%), Gaps = 69/454 (15%)

Query: 20  SLGAAGGFPGAASPGADPYGP-------REPPPPPPRYDPCAAAAPGAPGPPPPPHAYPF 72
           SLGA G   G A PGAD   P       R P    P+ D   +    AP         P 
Sbjct: 10  SLGA-GYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTLAAHPPLPL 68

Query: 73  APAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIV 132
            P A     A + PE   +               + GVS+ LE + LW EF+ +GTEMI+
Sbjct: 69  LPPAMGTEPAPSAPEALHS---------------LPGVSLSLENRELWKEFSSVGTEMII 113

Query: 133 TKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGR 192
           TKAGRRMFP  +V + G+DP A Y+ L+D +PVD  RYR+      W  +GKA+P  P R
Sbjct: 114 TKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRW--QGRRWEPSGKAEPRLPDR 171

Query: 193 VHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDS 252
           V+ HPDSPA GA WM+Q VSF ++KLTN+ LD +GH+IL+SMH+YQPR H+V    +  S
Sbjct: 172 VYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRA-AQLCS 230

Query: 253 EKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD----CDPEDWPRNHR 308
           + +      +F F ET F +VTAYQN +ITQLKIA+NPFAKGFR+    C  E   R  R
Sbjct: 231 QHWG--GMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKR 288

Query: 309 ------PGALPLMSAFARSRNPVASPTQPSGTEKDAAEARREFQRDA------GGP---- 352
                 P A     +      P  S       E D  +A    +  A      GGP    
Sbjct: 289 KLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEA 348

Query: 353 ------AVLGDPAHPPQLLARVLSPSLPGAGGAGGLVP-------LPGAPGGRPSPPNPE 399
                 A  G P+H P       SPS P A  +G   P       LP   GG   P  P 
Sbjct: 349 YLLHPAAFHGAPSHLP-----TRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPP 403

Query: 400 LRLEAPGASEPLHHHPYKYPAAAYDHYLGAKSRP 433
                P A   L   P+  P  A   YL   S+P
Sbjct: 404 ---AVPFAPHFLQGGPFPLPYTAPGGYLDVGSKP 434


>gi|158187509 T-box 22 isoform 1 [Homo sapiens]
          Length = 520

 Score =  223 bits (569), Expect = 2e-58
 Identities = 115/242 (47%), Positives = 149/242 (61%), Gaps = 13/242 (5%)

Query: 60  APGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKAL 119
           A G   P    P    + +A+S      G G S          ++ +   + ++L+   L
Sbjct: 51  AAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNS---------SESLEEKDIQMELQGSEL 101

Query: 120 WDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSW 179
           W  F+ +GTEMI+TKAGRRMFP+ +VK+ G+DP   Y + +D VPVD KRYRY +HSS W
Sbjct: 102 WKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQW 161

Query: 180 LVAGKADP-ATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQ 238
           +VAG  D      R + HPDSP  G  WM+QI+SFD++KLTNN +DD GHIIL SMH+Y+
Sbjct: 162 MVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYK 221

Query: 239 PRFHVVYVDPRKD---SEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGF 295
           PR HV+      D    +    E  KTF F+ET FT VTAYQN +IT+LKI  NPFAKGF
Sbjct: 222 PRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGF 281

Query: 296 RD 297
           RD
Sbjct: 282 RD 283


>gi|18375603 T-box 22 isoform 1 [Homo sapiens]
          Length = 520

 Score =  223 bits (569), Expect = 2e-58
 Identities = 115/242 (47%), Positives = 149/242 (61%), Gaps = 13/242 (5%)

Query: 60  APGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKAL 119
           A G   P    P    + +A+S      G G S          ++ +   + ++L+   L
Sbjct: 51  AAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNS---------SESLEEKDIQMELQGSEL 101

Query: 120 WDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSW 179
           W  F+ +GTEMI+TKAGRRMFP+ +VK+ G+DP   Y + +D VPVD KRYRY +HSS W
Sbjct: 102 WKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQW 161

Query: 180 LVAGKADP-ATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQ 238
           +VAG  D      R + HPDSP  G  WM+QI+SFD++KLTNN +DD GHIIL SMH+Y+
Sbjct: 162 MVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYK 221

Query: 239 PRFHVVYVDPRKD---SEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGF 295
           PR HV+      D    +    E  KTF F+ET FT VTAYQN +IT+LKI  NPFAKGF
Sbjct: 222 PRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGF 281

Query: 296 RD 297
           RD
Sbjct: 282 RD 283


>gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
          Length = 743

 Score =  221 bits (562), Expect = 2e-57
 Identities = 111/206 (53%), Positives = 140/206 (67%), Gaps = 25/206 (12%)

Query: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171
           V LE K LWD+F++ GTEM++TK+GRRMFP F+V+  G+D  A Y+LLMD +  DD RY+
Sbjct: 105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK 164

Query: 172 YAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNG---- 227
             FH+S W+VAGKADP  P R++ HPDSPA G QWM ++V+F KLKLTNN+ D +G    
Sbjct: 165 --FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLA 222

Query: 228 ----------------HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFT 271
                             ILNSMH+YQPRFH+V  +   D  K     F+T++F ET F 
Sbjct: 223 FPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYLFPETEFI 279

Query: 272 AVTAYQNHRITQLKIASNPFAKGFRD 297
           AVTAYQN +ITQLKI +NPFAKGFRD
Sbjct: 280 AVTAYQNDKITQLKIDNNPFAKGFRD 305


>gi|7019549 T-box 21 [Homo sapiens]
          Length = 535

 Score =  197 bits (501), Expect = 2e-50
 Identities = 125/287 (43%), Positives = 156/287 (54%), Gaps = 25/287 (8%)

Query: 25  GGFPGAASPGADPYGPREPPPP---------PPRYDPCAAAAPGAPGP-PPPPHAYPFAP 74
           GG  G+  PG    G   P PP         PPR  P AA  PGA    PPP  A  + P
Sbjct: 51  GGSLGSPYPG----GALVPAPPSRFLGAYAYPPR--PQAAGFPGAGESFPPPADAEGYQP 104

Query: 75  AAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTK 134
             G A         PG     A  A ++ + K+    V L    LW +FNQ  TEMI+TK
Sbjct: 105 GEGYAAPDPRAGLYPGPREDYALPAGLEVSGKLR---VALNNHLLWSKFNQHQTEMIITK 161

Query: 135 AGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPG-RV 193
            GRRMFP     + G++P + Y + +D V VD   +RY   S  W+  GKA+ + PG R+
Sbjct: 162 QGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRY--QSGKWVQCGKAEGSMPGNRL 219

Query: 194 HYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNG---HIILNSMHRYQPRFHVVYVDPRK 250
           + HPDSP  GA WM+Q VSF KLKLTNN    N     I+L S+H+YQPR H+V V+  +
Sbjct: 220 YVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGE 279

Query: 251 DSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
                   N   F F+ET+F AVTAYQN  ITQLKI +NPFAKGFR+
Sbjct: 280 PEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRE 326


>gi|122937388 MAX gene associated [Homo sapiens]
          Length = 3114

 Score =  196 bits (497), Expect = 5e-50
 Identities = 106/232 (45%), Positives = 137/232 (59%), Gaps = 10/232 (4%)

Query: 74  PAAGAATSAAAEPEGPGASCAAAAKAPVKKNAK--------VAGVSVQLEMKALWDEFNQ 125
           P  G              + A++  +PVK   K        V G++V L+  ++W+EF  
Sbjct: 31  PGNGKTDQGILVTNQDACALASSVSSPVKSKGKICLPADCTVGGITVTLDNNSMWNEFYH 90

Query: 126 LGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKA 185
             TEMI+TK GRRMFP  +  + G+D    Y+L+MD  PVD+ RY++  +   W  +GKA
Sbjct: 91  RSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDNHRYKW--NGRWWEPSGKA 148

Query: 186 DPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVY 245
           +P   GRV  HP+SP+ G  WM Q VSF KLKLTNN LD  GHIIL+SMHRY PR H+V 
Sbjct: 149 EPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVP 208

Query: 246 VDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
            +   +  +       TF F +T F AVTAYQN +ITQLKI  NPFAKGFRD
Sbjct: 209 AEKAVEVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRD 260


>gi|158187511 T-box 22 isoform 2 [Homo sapiens]
          Length = 400

 Score =  186 bits (473), Expect = 3e-47
 Identities = 91/163 (55%), Positives = 112/163 (68%), Gaps = 4/163 (2%)

Query: 139 MFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADP-ATPGRVHYHP 197
           MFP+ +VK+ G+DP   Y + +D VPVD KRYRY +HSS W+VAG  D      R + HP
Sbjct: 1   MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 60

Query: 198 DSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKD---SEK 254
           DSP  G  WM+QI+SFD++KLTNN +DD GHIIL SMH+Y+PR HV+      D    + 
Sbjct: 61  DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 120

Query: 255 YAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
              E  KTF F+ET FT VTAYQN +IT+LKI  NPFAKGFRD
Sbjct: 121 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRD 163


>gi|22538470 eomesodermin [Homo sapiens]
          Length = 686

 Score =  184 bits (467), Expect = 2e-46
 Identities = 117/297 (39%), Positives = 153/297 (51%), Gaps = 29/297 (9%)

Query: 27  FPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAE 85
           FP  A+ GA P+GP  P P   RY   +   PG  P    PP    F P AGA + A   
Sbjct: 163 FPYQAAAGA-PHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGS 221

Query: 86  PEG-------------------PGASCAAAAKAPVKKNAKVAG--VSVQLEMKALWDEFN 124
             G                   PGA+ A +           +G    V L  + LW +F+
Sbjct: 222 SGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFH 281

Query: 125 QLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGK 184
           +  TEMI+TK GRRMFP     + G++P A Y + ++ V  D   +R  F    W+  GK
Sbjct: 282 RHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR--FQGGKWVTCGK 339

Query: 185 ADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH---IILNSMHRYQPR 240
           AD    G +++ HP+SP  G+ WM+Q +SF KLKLTNN   +N +   I+L S+H+YQPR
Sbjct: 340 ADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPR 399

Query: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
            H+V V      +       +TF F ET+F AVTAYQN  ITQLKI  NPFAKGFRD
Sbjct: 400 LHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 47/193 (24%), Positives = 65/193 (33%), Gaps = 31/193 (16%)

Query: 331 PSGTEKDAAEARREFQRDAGGPAVLGDPAHPPQ-LLARVLSPSLPG-AGGAGGLVPLPGA 388
           PS  + D  +A ++F       AV G+PA       A +LS +  G A  +   V  PG 
Sbjct: 41  PSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGP 100

Query: 389 PGGRPSPPNPELRLEAPGAS----------------EPLHHHPYKY------------PA 420
           P GR   P  E  L +  A+                + L    Y              P 
Sbjct: 101 PDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPC 160

Query: 421 AAYDHYLGAKSRPAP-YPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAANMY 479
           + + +   A +   P YP P    + Y     P      V P   A     A A +    
Sbjct: 161 SLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGG 220

Query: 480 SSAGAAPPGSYDY 492
           SS G   PG+Y Y
Sbjct: 221 SSGGGGGPGTYQY 233



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 44/137 (32%), Positives = 53/137 (38%), Gaps = 34/137 (24%)

Query: 368 VLSPSLPGA---------GGAGGLVPLPGAPGGRPSPPNPEL-----RLEAPGASEPLHH 413
           V S +LPGA         GG+GG       P   PSP   +L     +     + E +  
Sbjct: 9   VSSVNLPGAHFYPLESARGGSGGSAG--HLPSAAPSPQKLDLDKASKKFSGSLSCEAVSG 66

Query: 414 HPYKY----PAA------AYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAA 463
            P       PAA      A D +  A +   P P  G +G        P         AA
Sbjct: 67  EPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPS--------AA 118

Query: 464 AAAAAAAAAAAAANMYS 480
           AAAAAAAAAAAA   YS
Sbjct: 119 AAAAAAAAAAAATARYS 135



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 4/69 (5%)

Query: 20  SLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAP----GPPPPPHAYPFAPA 75
           S  A  G P AAS GA      +           A A PG P    G P      P A A
Sbjct: 60  SCEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAA 119

Query: 76  AGAATSAAA 84
           A AA +AAA
Sbjct: 120 AAAAAAAAA 128


>gi|5730081 T-box, brain, 1 [Homo sapiens]
          Length = 682

 Score =  174 bits (442), Expect = 1e-43
 Identities = 103/220 (46%), Positives = 129/220 (58%), Gaps = 22/220 (10%)

Query: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171
           V L  + LW +F++  TEMI+TK GRRMFP     + G+DP A Y + +D +  D   +R
Sbjct: 206 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHWR 265

Query: 172 YAFHSSSWLVAGKADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNN--LLDDNGH 228
             F    W+  GKAD    G RV+ HPDSP  GA WM+Q +SF KLKLTNN    ++NG 
Sbjct: 266 --FQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQ 323

Query: 229 -IILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIA 287
            ++L S+H+YQPR HVV V+     +       +TF F ET+F AVTAYQN  ITQLKI 
Sbjct: 324 MVVLQSLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKID 383

Query: 288 SNPFAKGFRD--------CD-------PEDWPRNH-RPGA 311
            NPFAKGFRD        CD       P D PR+   PGA
Sbjct: 384 HNPFAKGFRDNYDTIYTGCDMDRLTPSPNDSPRSQIVPGA 423


>gi|4507339 transcription factor T [Homo sapiens]
          Length = 435

 Score =  172 bits (436), Expect = 6e-43
 Identities = 92/186 (49%), Positives = 114/186 (61%), Gaps = 10/186 (5%)

Query: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171
           V LE   LW  F +L  EMIVTK GRRMFP  +V + G+DP A Y  L+DFV  D+ R++
Sbjct: 44  VGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWK 103

Query: 172 YAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIIL 231
           Y   +  W+  GK +P  P  V+ HPDSP  GA WMK  VSF K+KLTN  L+  G I+L
Sbjct: 104 YV--NGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNK-LNGGGQIML 160

Query: 232 NSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPF 291
           NS+H+Y+PR H+V V          +    +  F ET+F AVTAYQN  IT LKI  NPF
Sbjct: 161 NSLHKYEPRIHIVRVGG-------PQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPF 213

Query: 292 AKGFRD 297
           AK F D
Sbjct: 214 AKAFLD 219


>gi|4827024 T-box 19 [Homo sapiens]
          Length = 448

 Score =  169 bits (429), Expect = 4e-42
 Identities = 92/198 (46%), Positives = 119/198 (60%), Gaps = 14/198 (7%)

Query: 110 VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 169
           + + LE   LW  F ++  EMIVTK GRRMFP  ++ + G+DP A Y LL+DFVP D  R
Sbjct: 41  LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100

Query: 170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI 229
           ++Y   +  W+ AGK + ++   V+ HPDSP  GA WMK  +SF K+KLTN  L+  G I
Sbjct: 101 WKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQI 157

Query: 230 ILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASN 289
           +LNS+H+Y+P+ H+V V         A        F ET+F AVTAYQN  IT LKI  N
Sbjct: 158 MLNSLHKYEPQVHIVRVGS-------AHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210

Query: 290 PFAKGFRDCDPEDWPRNH 307
           PFAK F D       RNH
Sbjct: 211 PFAKAFLDAK----ERNH 224


>gi|239755362 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 112

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 40/83 (48%), Positives = 49/83 (59%), Gaps = 11/83 (13%)

Query: 309 PGALPLMSAFARSRNPVASPTQPSGT-----------EKDAAEARREFQRDAGGPAVLGD 357
           PG L   +A  R    V  P +  G+             + AEAR++FQR+  GPAV+GD
Sbjct: 27  PGVLEQRAALVRDSTAVQEPRRRGGSGMACCRSPALPHGEVAEARQKFQREVSGPAVVGD 86

Query: 358 PAHPPQLLARVLSPSLPGAGGAG 380
           PA PPQLLA+VLSPSLPGA  AG
Sbjct: 87  PAPPPQLLAQVLSPSLPGASSAG 109


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 48/136 (35%), Positives = 56/136 (41%), Gaps = 20/136 (14%)

Query: 362 PQLLARVLSPSLPGAGGAGGLVPLPGAPGGRPSPPNPE--------LRLEAPGASEPLHH 413
           P  L   L+ +  G GG GG     G   G  SP + E        LR E+P     L  
Sbjct: 27  PLALVTSLAAAASGTGGGGGGGGASGGTSGSCSPASSEPPAAPADRLRAESPSPPRLLAA 86

Query: 414 HPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAAAAAAA 473
           H    P   +   LGA          G  G G   H  PHHH HP + AAAAAAAAAAAA
Sbjct: 87  HCALLPKPGF---LGAGGGG------GGTGGG---HGGPHHHAHPGAAAAAAAAAAAAAA 134

Query: 474 AAANMYSSAGAAPPGS 489
               +    G A  G+
Sbjct: 135 GGLALGLHPGGAQGGA 150



 Score = 36.2 bits (82), Expect = 0.070
 Identities = 50/166 (30%), Positives = 59/166 (35%), Gaps = 43/166 (25%)

Query: 331 PSGTEKDAAEARREFQRDAGGPAVLGDPAHPPQLLAR----VLSPSLPGAGGAGGLVPLP 386
           P+ +E  AA A R          +  +   PP+LLA     +  P   GAGG GG     
Sbjct: 60  PASSEPPAAPADR----------LRAESPSPPRLLAAHCALLPKPGFLGAGGGGG----- 104

Query: 387 GAPGGRPSPPNPELRLEAPGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGY 446
           G  GG   P +              H HP    AAA      A    A    PG    G 
Sbjct: 105 GTGGGHGGPHH--------------HAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGA 150

Query: 447 HPHAHPHHHHHPVSPAAAAAAAAAAAAAAANMYSSAGAAPPGSYDY 492
              A    + HPV   +AAAAAAA           AG  P  SY Y
Sbjct: 151 GLPAQAALYGHPVYGYSAAAAAAAL----------AGQHPALSYSY 186



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 30/88 (34%), Positives = 35/88 (39%), Gaps = 21/88 (23%)

Query: 22  GAAGGFPGAASPGAD--PYGP----REPPPPPPRYDPCAAAAPGAPG------------- 62
           GA+GG  G+ SP +   P  P    R   P PPR      A    PG             
Sbjct: 49  GASGGTSGSCSPASSEPPAAPADRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGGTGG 108

Query: 63  --PPPPPHAYPFAPAAGAATSAAAEPEG 88
               P  HA+P A AA AA +AAA   G
Sbjct: 109 GHGGPHHHAHPGAAAAAAAAAAAAAAGG 136


>gi|18959212 GS homeobox 2 [Homo sapiens]
          Length = 304

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 23/33 (69%), Positives = 25/33 (75%)

Query: 444 HGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAA 476
           H +HP  H HHHH P  P +AAAAAAAAAAAAA
Sbjct: 127 HHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAA 159


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 41/94 (43%), Positives = 43/94 (45%), Gaps = 16/94 (17%)

Query: 23  AAGGFPGAASPGA--DPYGPREPPPPPPRYDPCAAAAPGAP-GPP------PPPHAYPFA 73
           AA   P A SP A   P  P   PPPPP      A  PG P GPP      PPP A    
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306

Query: 74  PAAGAATS---AAAEPEG----PGASCAAAAKAP 100
            +AGAA +   AA  P G    PG   AAAA AP
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 45/134 (33%), Positives = 52/134 (38%), Gaps = 36/134 (26%)

Query: 2   HFSTVTRDMEAFTASSL-------SSLGAAGGFPGA---ASPGADPY------------G 39
           H +  T ++ A  A +L       S  GAAG  P A    +PGA P             G
Sbjct: 42  HLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGG 101

Query: 40  PREPPPPPPRYDPCAAAAPGAPG----PPPPPHAYPFAPAAGAATSAA---------AEP 86
           P+ P PP PR  P   A P  P     PPP   A   AP   AA  AA         A+P
Sbjct: 102 PQRPGPPSPR-RPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160

Query: 87  EGPGASCAAAAKAP 100
            GP A  A A   P
Sbjct: 161 AGPAALAARAGPGP 174



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 45/118 (38%), Positives = 49/118 (41%), Gaps = 16/118 (13%)

Query: 12  AFTASSLSSLGAAG--GFPGAASPGA----DPYGPREPPPPPPRYDPCAAAAPGAPG--P 63
           A  A SL + G A     P  A+PG      P+     PP P    P AA AP AP   P
Sbjct: 211 AAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP 270

Query: 64  PPPPH-----AYPFAPAAGAATSAAAEPEGPGA---SCAAAAKAPVKKNAKVAGVSVQ 113
           PPPP      A P    AG  T+A A P    A     A AA AP       AGVS Q
Sbjct: 271 PPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQ 328



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 37/109 (33%), Positives = 40/109 (36%), Gaps = 8/109 (7%)

Query: 368 VLSPSLPGAGGAGGLVPLPGAPGGRPSPPNP-ELRLEAPGASEPLHHHPYKYPAAAYDHY 426
           V+S S  GA GAG   P  GAPG  P PP     R    G   P    P +    A    
Sbjct: 62  VVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121

Query: 427 LGAKSRPAP-------YPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAA 468
             AK RP P        P+P        P   P     P  PAA AA A
Sbjct: 122 PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 59/210 (28%), Positives = 76/210 (36%), Gaps = 27/210 (12%)

Query: 304 PRNHRPGALPLMSAFARSRNPVASPTQP-----------SGTEKDAAEARREFQRDAGG- 351
           P    PGA P      R+R     P +P           +G    AA+ R   +  AG  
Sbjct: 78  PAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSC 137

Query: 352 ---PAVLGDPAHPPQLLARVLSPSLP-------GAGGAGGLVPLPGAPGGRPSPPNPELR 401
              PA     A P    A    P+ P       G G   G  P PG   G+P+ P     
Sbjct: 138 APVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQT 197

Query: 402 LEAPGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYP-LPG--LRGHGYHPHAHPHHHHHP 458
           L   G++  L+ H    PA +  +   A   P P P  PG  ++   +   A P     P
Sbjct: 198 LN--GSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAP 255

Query: 459 VSPAAAAAAAAAAAAAAANMYSSAGAAPPG 488
             PAA A AA AAA        +  A PPG
Sbjct: 256 SPPAAPAPAAPAAAPPPPPPAPATLARPPG 285



 Score = 36.2 bits (82), Expect = 0.070
 Identities = 53/197 (26%), Positives = 65/197 (32%), Gaps = 22/197 (11%)

Query: 304 PRNHRPGALPLMSAFARSRNPVA--SPTQPSGTEKDAAEARREFQRDAGGPAVL----GD 357
           P+   PG +     F  +  P A  +P+ P+     A  A       A  PA L    G 
Sbjct: 229 PKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPA--PATLARPPGH 286

Query: 358 PAHPPQLLARVLSPSLPGAGGAGGLVPLP----GAPGGRPSPPNPELRLEAPG----ASE 409
           PA PP     V  P+    GG+ G  P P    G P G    P P     AP     A  
Sbjct: 287 PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAES 346

Query: 410 PLHHHPYKYPAAAYDHYLGAKSRPAPYPL-PGLRGHGYHPHAHPHHHHHPVSPAAAAAAA 468
           P        PAA      G  S  A   + P ++G    P A P     P +P       
Sbjct: 347 PKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP-----PPAPGTPTGLP 401

Query: 469 AAAAAAAANMYSSAGAA 485
             AA A     S    A
Sbjct: 402 KGAAGAVTQSLSRTPTA 418



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 27/95 (28%), Positives = 34/95 (35%), Gaps = 10/95 (10%)

Query: 20  SLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAA 79
           S G+    P AA+  A P      P  P      AA A   PGP P P   P        
Sbjct: 133 SAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGP-------- 184

Query: 80  TSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQL 114
                +P GPGA+      A +  +   A  +V L
Sbjct: 185 --GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL 217



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 31/115 (26%), Positives = 36/115 (31%), Gaps = 28/115 (24%)

Query: 13  FTASSLSSLGAAGGFPGAASPGADPYGPREPPPPP-----------------PRYDPCAA 55
           F  ++     AA   P A +P A    P  PPP P                 P   P AA
Sbjct: 243 FVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAA 302

Query: 56  AAPG-----------APGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKA 99
           A  G           A G P      P   AA AA +   + E P     AA  A
Sbjct: 303 AQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPA 357


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 38/92 (41%), Positives = 41/92 (44%), Gaps = 13/92 (14%)

Query: 19  SSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAG- 77
           S  G+ GG  G    GA        PPPPP   P A AAP  P PPPPP A   APA+G 
Sbjct: 46  SPAGSPGGGAGGEGLGAAAAALLLHPPPPP---PPATAAPPPPPPPPPPPASAAAPASGP 102

Query: 78  -AATSAAAEPEGPG--------ASCAAAAKAP 100
            A    AA P   G        A  +AAA  P
Sbjct: 103 PAPPGLAAGPGPAGGAPTPALVAGSSAAAPFP 134



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 38/90 (42%), Positives = 41/90 (45%), Gaps = 15/90 (16%)

Query: 22  GAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATS 81
           GA G   GAA+     +    PPPPPP     A AAP  P PPPPP A   APA+G    
Sbjct: 54  GAGGEGLGAAAAALLLH---PPPPPPP-----ATAAPPPPPPPPPPPASAAAPASGPPA- 104

Query: 82  AAAEPEGPGASCAAAAKAPVKKNAKVAGVS 111
               P G  A    A  AP    A VAG S
Sbjct: 105 ----PPGLAAGPGPAGGAPTP--ALVAGSS 128



 Score = 33.1 bits (74), Expect = 0.60
 Identities = 25/73 (34%), Positives = 29/73 (39%), Gaps = 19/73 (26%)

Query: 42  EPPPPPPRYDPCAAAAPGAPGPPPPPHAY--------PFAPAAGAATSAAAEP------E 87
           +PPPPPP+              PPPP A         P  PA  A +S A  P      E
Sbjct: 4   QPPPPPPQQQQQQQQLS-----PPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGE 58

Query: 88  GPGASCAAAAKAP 100
           G GA+ AA    P
Sbjct: 59  GLGAAAAALLLHP 71



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 26/87 (29%), Positives = 32/87 (36%), Gaps = 3/87 (3%)

Query: 312 LPLMSAFARSRNPVASPTQPSGTEK-DAAEARREFQRDAGGPAVLGDPAHPPQLLARVLS 370
           LP   A +   +P  SP   +G E   AA A          P     P  PP       S
Sbjct: 35  LPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPAS 94

Query: 371 PSLPGAGGAG--GLVPLPGAPGGRPSP 395
            + P +G     GL   PG  GG P+P
Sbjct: 95  AAAPASGPPAPPGLAAGPGPAGGAPTP 121


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,207,912
Number of Sequences: 37866
Number of extensions: 1873432
Number of successful extensions: 46795
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 788
Number of HSP's successfully gapped in prelim test: 1189
Number of HSP's that attempted gapping in prelim test: 18404
Number of HSP's gapped (non-prelim): 18489
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.