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Search of human proteins with 17999539
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo
sapiens]
(1227 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 2474 0.0
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 761 0.0
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 688 0.0
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 575 e-164
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 558 e-158
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 523 e-148
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 496 e-140
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 367 e-101
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 352 2e-96
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 349 8e-96
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 295 2e-79
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 287 4e-77
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 282 2e-75
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 271 3e-72
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 251 4e-66
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 251 4e-66
gi|166851804 tudor domain containing 9 [Homo sapiens] 221 3e-57
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 186 1e-46
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 183 8e-46
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 157 6e-38
gi|38505213 YTH domain containing 2 [Homo sapiens] 157 8e-38
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 80 9e-15
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 78 6e-14
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 78 6e-14
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 74 9e-13
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 74 9e-13
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 69 2e-11
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 67 1e-10
gi|148746195 trichohyalin [Homo sapiens] 65 3e-10
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 64 7e-10
>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
Length = 1227
Score = 2474 bits (6413), Expect = 0.0
Identities = 1227/1227 (100%), Positives = 1227/1227 (100%)
Query: 1 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR 60
MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
Sbjct: 1 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR 60
Query: 61 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH 120
EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
Sbjct: 61 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH 120
Query: 121 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS 180
PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
Sbjct: 121 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS 180
Query: 181 RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR 240
RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
Sbjct: 181 RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR 240
Query: 241 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG 300
DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
Sbjct: 241 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG 300
Query: 301 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ 360
EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
Sbjct: 301 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ 360
Query: 361 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR 420
KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
Sbjct: 361 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR 420
Query: 421 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG 480
IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
Sbjct: 421 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG 480
Query: 481 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE 540
VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
Sbjct: 481 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE 540
Query: 541 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE 600
LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
Sbjct: 541 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE 600
Query: 601 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN 660
MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
Sbjct: 601 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN 660
Query: 661 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ 720
TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
Sbjct: 661 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ 720
Query: 721 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS 780
EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
Sbjct: 721 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS 780
Query: 781 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL 840
QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
Sbjct: 781 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL 840
Query: 841 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS 900
QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
Sbjct: 841 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS 900
Query: 901 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI 960
LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
Sbjct: 901 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI 960
Query: 961 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN 1020
VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
Sbjct: 961 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN 1020
Query: 1021 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ 1080
NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
Sbjct: 1021 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ 1080
Query: 1081 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW 1140
AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
Sbjct: 1081 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW 1140
Query: 1141 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR 1200
LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
Sbjct: 1141 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR 1200
Query: 1201 STKIYTPGRKEQGEPMTPRRTPARFGL 1227
STKIYTPGRKEQGEPMTPRRTPARFGL
Sbjct: 1201 STKIYTPGRKEQGEPMTPRRTPARFGL 1227
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 761 bits (1966), Expect = 0.0
Identities = 457/1111 (41%), Positives = 651/1111 (58%), Gaps = 123/1111 (11%)
Query: 131 RSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSER 190
+ +QR+ E R+ + K+++ ++++RDRD DR+R+RD + RH SRS R
Sbjct: 159 QEKQRDAEHRDR----TKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSR---SRSR 211
Query: 191 SSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLST 250
+ RN+ +S Y S RSQ SP +D ++
Sbjct: 212 TRERNKVKSR---------------------YRSRSRSQ----SPPKDRKDRDK---YGE 243
Query: 251 RDRDRSVRGKYSDDTPLPTPSYK--YNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDT 308
R+ DR R K+ D P P+ YN G +L G +R EG IS
Sbjct: 244 RNLDRW-RDKHVDRPPPEEPTIGDIYNGKVTSIMQFGCFVQLE-GLRKRWEGLVHISELR 301
Query: 309 EEERQQWEDD-----QR-----------QADRDWYMMDEGYDEFHNP------LAYSSED 346
E R D QR + +D+ E NP + ++E+
Sbjct: 302 REGRVANVADVVSKGQRVKVKVLSFTGTKTSLSMKDVDQETGEDLNPNRRRNLVGETNEE 361
Query: 347 YVRR---REQHLHKQKQKRI---SAQRRQINE--DNERWETNRMLTSGVVHRLEVDE--- 395
R R HL + S +R+++ D E+WE +M+ + V+ + E +
Sbjct: 362 TSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFPDFDE 421
Query: 396 --------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKG 447
D EED ++ L+ PPFL G + P+ VK+ L+ A
Sbjct: 422 ETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVKNPDGSLSQAAMMQ 479
Query: 448 SQTVRKHREQKERKKAQ---------HKHW----------ELAGTKLGDIMGVKKEEEPD 488
S ++ RE K+ ++ +KHW ++A G +G+ + P+
Sbjct: 480 SALAKERRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRG--IGMMPNDIPE 537
Query: 489 KAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDN 548
+ H ++AS + SILEQR+ LPI+ ++++L+ + DN
Sbjct: 538 ----------------WKKHAFGGNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDN 581
Query: 549 SIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNLGEE 608
I+IV+GETGSGKTTQ+TQYL E GYT G IGCTQPRRVAAMSVAKRVSEE G LG+E
Sbjct: 582 QILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQE 641
Query: 609 VGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLL 668
VGY IRFEDCTS T+IKYMTDG+LLRE L + DL Y+ I++DEAHER+++TDVLFGLL
Sbjct: 642 VGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLL 701
Query: 669 REVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAV 728
++ V +R D+KLIVTSAT+DA KF+ +F PIF IPGRT+PV+IL++K P+ DY++A++
Sbjct: 702 KKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASL 761
Query: 729 KQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPSDLQ 787
+Q+HL+ PGDIL+F+ GQE+I+ + + E ++ L + P L +LP+YS LPS++Q
Sbjct: 762 ITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQ 821
Query: 788 AKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQ 847
+IF AP G RK ++ATNIAETSLT+DGI +V+D G+ K KV+N + G+D L + PISQ
Sbjct: 822 TRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQ 881
Query: 848 ANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLL 907
A A QR+GRAGRTGPG+C+RLYT+ AY++E+LTT VPEIQRTNLA+ VL LK++G+ DLL
Sbjct: 882 AQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLL 941
Query: 908 QFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGC 967
F FMD PP + ++ +M QL+ LGALD+ G LT GR M EFPL+P L KMLI+S +GC
Sbjct: 942 SFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGC 1001
Query: 968 SSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIW 1027
S E+L IVSMLSV +FYRPK ++ +DQ + KF E DHLT L VY WKNN +S W
Sbjct: 1002 SEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPW 1061
Query: 1028 CNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGI 1087
C ++FI A+++R+ +++R Q+ IM + ++ + SCG V+K IC+ +F AAK
Sbjct: 1062 CYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQ 1121
Query: 1088 GEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPM 1147
Y + ++HP+S+LF P+++VYHELV+TTKEYM+ VT +D WL E P
Sbjct: 1122 EGYRTLIDQQVVYIHPSSALFNR--QPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPA 1179
Query: 1148 FYSVKQAGK-SRQENRRRAKEEASAMEEEMA 1177
F+ V K S+Q+ ++R + + EE A
Sbjct: 1180 FFKVSDPTKLSKQKKQQRLEPLYNRYEEPNA 1210
>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
Length = 1041
Score = 688 bits (1776), Expect = 0.0
Identities = 377/894 (42%), Positives = 545/894 (60%), Gaps = 50/894 (5%)
Query: 294 RGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQ 353
+G+++ G + E +WE +R+ +D D + + + + R ++
Sbjct: 143 KGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDK 202
Query: 354 HLHKQKQKRISA---QRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVH 410
+++ QKR+ R+ + + + L +LE D E + A +
Sbjct: 203 KAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLE---DLEAELADE------ 253
Query: 411 NLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKGSQ------TVRKHREQKERKKA- 463
FL G + ++ + K DLA R + T R H ++ R +
Sbjct: 254 ----EFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPA 309
Query: 464 ---------------QHKHWE-----LAGTKLGDIMGVKKEEEPDKAVTEDGKVDY-RTE 502
+ + WE A K G +E + + E+ +++ R
Sbjct: 310 RAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRAT 369
Query: 503 QKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKT 562
Q D S++ +K+SI R+ LP+F ++ELL I ++ ++I+ GETGSGKT
Sbjct: 370 QLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKT 429
Query: 563 TQLTQYLHEDGYTDYGM-IGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSE 621
TQ+ QYL E+GYT+ GM I CTQPRRVAAMSVA RV+ EMG LG EVGY+IRFEDCTSE
Sbjct: 430 TQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSE 489
Query: 622 NTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLI 681
T+++YMTDG+LLRE L E DL YS +++DEAHER+L+TD+LFGL+++V R +LK++
Sbjct: 490 RTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVL 549
Query: 682 VTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLSGAPG 741
V SATMD +F+ FF + P+F IPGR FPVDI ++K P+ DY+EA V LQ+H++ PG
Sbjct: 550 VASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPG 609
Query: 742 DILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRK 800
DIL+F+ GQE+IE + + + L L VLPIY+ LPSD+QA+IFQ P G RK
Sbjct: 610 DILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARK 669
Query: 801 CIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRT 860
+VATNIAETS T++GI++V+D G+CK K +NPR GM++L + P S+A+ANQR+GRAGR
Sbjct: 670 VVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRV 729
Query: 861 GPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNM 920
G+CFRLYT AY++EL TTVPEIQRT+L NVVLLLKSLG+ DL+ F F+DPPP + +
Sbjct: 730 AAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETL 789
Query: 921 LNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSV 980
L ++ QL+ LGAL++ G LT++GR M E P+DP LSKM++ S CS EIL + +MLSV
Sbjct: 790 LLTLEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSV 849
Query: 981 -PAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMR 1039
+IFYRPK + +D R F +P DHL LNVY QW + YS+ WC ++F+ ++MR
Sbjct: 850 NNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRSMR 909
Query: 1040 KVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEYVNIRTGMPC 1099
+ R+VR QL+ ++ + + L+SC D+ VRK I A YF+ A+L G Y ++
Sbjct: 910 RARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSG-YRTVKQQQTV 968
Query: 1100 HLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVKQ 1153
+HP SSLF P +++YHELV+TTKE+M+ V ++ WL E+ P +Y K+
Sbjct: 969 FIHPNSSLFEQ--QPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKE 1020
Score = 43.5 bits (101), Expect = 0.001
Identities = 53/202 (26%), Positives = 84/202 (41%), Gaps = 21/202 (10%)
Query: 4 TSEDASIHRLEGTD---LDCQVGGLICKSKSAASEQHVFKAPA---PRPSLLGLDLLASL 57
TS + + RL TD L + + + V + PA R + L+ S
Sbjct: 38 TSAEEFVQRLRDTDTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSY 97
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
+ E E+ E ++ S K ++ K +K EEE ++A + +K + E
Sbjct: 98 RLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEK 157
Query: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDER-DRS 176
P SE+ WER+ ERER + EE+D E+ R RD DR R+ ER D+
Sbjct: 158 PE-----SEDEWERT---ERERLQ------DLEERDAFAERVRQRDKDRTRNVLERSDKK 203
Query: 177 RHSSRSERDGGSERSSRRNEPE 198
+ +R +E + PE
Sbjct: 204 AYEEAQKRLKMAEEDRKAMIPE 225
Score = 38.9 bits (89), Expect = 0.030
Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 4/154 (2%)
Query: 104 IRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRD 163
+ K+R YR S VS S Q++R++R+H +EE++ EK + +
Sbjct: 91 LEKNRSYRLLEDSEESSEETVSRA--GSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKT 148
Query: 164 YDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAA--TPSRSTWEEEDSG 221
K+ ++ + R+ER+ + R E R R KD RS + +
Sbjct: 149 GGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEA 208
Query: 222 YGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDR 255
+ ++ + + P R R L+ R+R++
Sbjct: 209 QKRLKMAEEDRKAMIPELRKKSRREYLAKREREK 242
Score = 38.5 bits (88), Expect = 0.040
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 40/181 (22%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
K+RE EE+++ +K K K K + +K E+ ++ + +D R A
Sbjct: 130 KKREEEEEEEASEKGKKKTGGSK-----QQTEKPESEDEWERTERERLQDLEERDA---- 180
Query: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKE------------EKDWK------KEKS 159
F ER RQR+++R + + S K+ E+D K ++KS
Sbjct: 181 ----------FAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKS 230
Query: 160 RDRDYDRKRDRDERDRSRHSSRSER--DGGSERSSRRNEPESPRHRPKDAATPSRSTWEE 217
R R+Y KR+R++ + E G E S + + R +D A R+ E+
Sbjct: 231 R-REYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQ 289
Query: 218 E 218
E
Sbjct: 290 E 290
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapiens]
Length = 795
Score = 575 bits (1482), Expect = e-164
Identities = 303/662 (45%), Positives = 438/662 (66%), Gaps = 25/662 (3%)
Query: 525 ILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGM---IG 581
IL++R LP++ + I+ + ++VGETGSGKTTQ+ Q+ E + G +
Sbjct: 130 ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVA 189
Query: 582 CTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREA 641
CTQPRRVAAMSVA+RV++EM LG+EVGY+IRFEDC+S T++KYMTDG+LLRE++ +
Sbjct: 190 CTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDP 249
Query: 642 DLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPI 701
L+ Y II+DEAHER+L TD+L G+L+EVV +RSDLK+IV SAT+DA KF +F N P+
Sbjct: 250 LLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPL 309
Query: 702 FHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHL-SGAPGDILIFMPGQEDIEVTSDQI 760
IPGRT PV+I ++ P+ DY+EAA++ +Q+H+ GD+L+F+ GQE+I+ +I
Sbjct: 310 LTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRI 369
Query: 761 VEHLEEL-ENAPALAVLPIYSQLPSDLQAKIFQKAP----DGV--RKCIVATNIAETSLT 813
+++L + ++P+YS LP Q +IF+ P +G RK +V+TNIAETSLT
Sbjct: 370 KREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLT 429
Query: 814 VDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSA 873
+DG++FVID G+ K KV+NPRI +++L + IS+A+A QR+GRAGRT PG+CFRLYT+ A
Sbjct: 430 IDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKA 489
Query: 874 YKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGAL 933
YK E+ T PEI R+NL +VVL LK LG+ DL+ F FMDPP + ++ ++ L L AL
Sbjct: 490 YKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAAL 549
Query: 934 DNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEE 993
++ G LT G +M EFPLDP L+KM+I SCD CS+E+L I +MLSVP F RP ++
Sbjct: 550 NDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKA 609
Query: 994 SDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMV 1053
+D+ + +FA + DHLT LNVY +K N+ S WC D+FI+ +++ VR QL IM
Sbjct: 610 ADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIM- 668
Query: 1054 QQRMSLASCGTDWDI------VRKCICAAYFHQAAKLKGIGEYVNIRTGMPCHLHPTSSL 1107
R +L TD+ +RK + YF Q A L+ G Y+ ++ LHP++ L
Sbjct: 669 -DRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVL 727
Query: 1108 FGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVK---QAGKSRQENRRR 1164
+ P++++Y+E V+TTK Y++ T + EWL ++ P +Y + Q RQ +R
Sbjct: 728 ---DHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRII 784
Query: 1165 AK 1166
AK
Sbjct: 785 AK 786
Score = 33.1 bits (74), Expect = 1.7
Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 156 KEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPE 198
K+++ DR RDRD DRS+ R ERD G R E E
Sbjct: 17 KKRAGTDGKDRDRDRDREDRSKDRDR-ERDRGDREREREKEKE 58
Score = 30.8 bits (68), Expect = 8.3
Identities = 18/55 (32%), Positives = 27/55 (49%)
Query: 136 ERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSER 190
+R R + G S +++ K RDRD DR+ +RDR R ER+ E+
Sbjct: 3 KRHRLDLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEK 57
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapiens]
Length = 703
Score = 558 bits (1438), Expect = e-158
Identities = 291/659 (44%), Positives = 430/659 (65%), Gaps = 21/659 (3%)
Query: 524 SILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYG-MIGC 582
SI +QRQ LP+F ++ +L +I + V++VGETG GK+TQ+ QYL E G+T G ++G
Sbjct: 46 SIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGV 105
Query: 583 TQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSE-NTLIKYMTDGILLRESLREA 641
TQPRRVAA++VA RV+EE G LG EVGY IRF+DCT + T IK++TDG+L+RE + +
Sbjct: 106 TQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDP 165
Query: 642 DLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGN--- 698
L YS I++DEAHER+L TD+ GLL+++ +R DL+LIV SAT+DA+KF FF
Sbjct: 166 LLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNET 225
Query: 699 -------VPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLSGAPGDILIFMPGQE 751
I + GRTFPVDI + ++P DY+++ V+ +++H + GD+L F+ GQE
Sbjct: 226 SDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQE 285
Query: 752 DIEVTSDQIVEHLEELENAPA---LAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIA 808
++E ++E L L VLP+Y+ LPS Q K+F++ VRK IVATN+A
Sbjct: 286 EVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVA 345
Query: 809 ETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRL 868
ETS+T+ GI++VID G+ KL+ +NPR ++ L + P+SQA+ANQR+GR GR+ G+C+RL
Sbjct: 346 ETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRL 405
Query: 869 YTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLW 928
YT+ A+ ++L +TVPE+QR+NLA V+L LK+LG+ ++L+FHFM PPP +M+ ++ L+
Sbjct: 406 YTEEAF-DKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLY 464
Query: 929 ILGALDNTGGLTST-GRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRP 987
LG LD LT G + EFPL+P +KML+ S + GCS EIL I +M+ + IF P
Sbjct: 465 ALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVP 524
Query: 988 KGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQ 1047
++ + ++ KFAV E DHLT LN+Y + +N + WC +HF++ K + + VR Q
Sbjct: 525 PNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQ 584
Query: 1048 LKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEYVNIRTGMPCHLHPTSSL 1107
LK ++V+ ++ S D D+V +CI + +F AA+ G Y IR H+HP S L
Sbjct: 585 LKKLLVKFQVPRKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASVL 644
Query: 1108 FGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVKQAGKSRQENRRRAK 1166
+ P +++Y+E++ T+K YM+ VTA++ WL EL P FY Q G +RAK
Sbjct: 645 YA-EKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFY---QQGTHLSLKAKRAK 699
>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapiens]
Length = 707
Score = 523 bits (1348), Expect = e-148
Identities = 279/637 (43%), Positives = 411/637 (64%), Gaps = 17/637 (2%)
Query: 528 QRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRR 587
QR+ LPIF + +LL +R+ +++GETGSGKTTQ+ QYL+E G + G+I TQPRR
Sbjct: 70 QRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQGIIAVTQPRR 129
Query: 588 VAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYS 647
VAA+S+A RVS+E LG+ VGY +RF+D TSE+T IK++TDG+LLRE++ ++ L YS
Sbjct: 130 VAAISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKFLTDGMLLREAISDSLLRKYS 189
Query: 648 AIIMDEAHERSLNTDVLFGLLREVVARRSD-----LKLIVTSATMDAEKFAAFFGNVPIF 702
+I+DEAHER+++TDVLFG+++ RR + LK+IV SATMD + F+ +F P+
Sbjct: 190 CVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNGAPVL 249
Query: 703 HIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLSG-APGDILIFMPGQEDIEV---TSD 758
++ GR P+ + ++K PQ DY+ AA+ Q+H + DIL+F+ GQE+IE T
Sbjct: 250 YLEGRQHPIQVFYTKQPQNDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEIEAMSKTCR 309
Query: 759 QIVEHLEELENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIM 818
I +HL + PA+ VLP+Y+ LP Q ++FQ AP G RK I++TNIAETS+T+ GI
Sbjct: 310 DIAKHLP--DGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIISTNIAETSITITGIK 367
Query: 819 FVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNEL 878
+V+D+G K K +NP G++ L + +S+ A QR+GRAGR G C+RLYT+ ++ +
Sbjct: 368 YVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFE-KF 426
Query: 879 LTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGAL---DN 935
TVPEIQR NLA+V+L L ++ V ++L F FM P D++ ++ QL +LGAL D+
Sbjct: 427 DKMTVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSKPSPDHIQAAIAQLDLLGALEHKDD 486
Query: 936 TGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESD 995
LT GR M FPL+P +K +++S C+ EIL IVS+LSV ++ + P R EE
Sbjct: 487 QLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSLLSVDSVLHNPPSRREEVQ 546
Query: 996 QIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQ 1055
+R+KF E DH+T LN+Y +KN + WC ++F+++K M V EVRAQL+DI ++
Sbjct: 547 GVRKKFISSEGDHMTLLNIYRTFKNLGGNKDWCKENFVNSKNMTLVAEVRAQLRDICLKM 606
Query: 1056 RMSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPD 1115
M +AS D + VR+C+ + F A+L+ G Y T P +HP+S LF P
Sbjct: 607 SMPIASSRGDVESVRRCLAHSLFMSTAELQPDGTYATTDTHQPVAIHPSSVLFHC--KPA 664
Query: 1116 YIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVK 1152
+VY EL+ T K YM+ + +D +WL E P ++ K
Sbjct: 665 CVVYTELLYTNKCYMRDLCVIDAQWLYEAAPEYFRRK 701
>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapiens]
Length = 779
Score = 496 bits (1278), Expect = e-140
Identities = 268/699 (38%), Positives = 429/699 (61%), Gaps = 37/699 (5%)
Query: 533 PIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMS 592
PI +++++ +RDNS +IV G TGSGKTTQL +YL+E G++ +GMIG TQPR+VAA+S
Sbjct: 54 PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAIS 113
Query: 593 VAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMD 652
VA+RV+EEM LG +VGY +RF+DC+S+ T IKYMTDG LL+ L + +L +S II+D
Sbjct: 114 VAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILD 173
Query: 653 EAHERSLNTDVLFGLLREVVA-----RRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGR 707
EAHER+L TD+LFGLL+++ R+ LK++V SATM+ K +AFFGN PIF IPGR
Sbjct: 174 EAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGR 233
Query: 708 TFPVDILFSKT--PQED----YVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIV 761
+PV F P++ Y++A V+ ++ +HL+ GDIL+F+ GQ +IE + + +
Sbjct: 234 LYPVREKFCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLF 293
Query: 762 EHLEELE--------NAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLT 813
+ E ++ L +LP Y + +D Q +IF P G+RKC+++TNI+ TSLT
Sbjct: 294 QMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLT 353
Query: 814 VDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSA 873
+DGI +V+D G+ K NPR+G+D L++ PIS++ A QRSGRAGRT G+CFR+Y++
Sbjct: 354 IDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDF 413
Query: 874 YKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGAL 933
+ + +PEI+RT+L +VVL LK L + D+++F ++DPP E +L ++ QL+ A+
Sbjct: 414 WNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAI 473
Query: 934 DNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGRE-- 991
D +G +T G MVEFPL P L+ +I + + C +L I +MLSV +F RP E
Sbjct: 474 DRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQ 533
Query: 992 EESDQIREKFAVPE---SDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQL 1048
+E++Q + A +D T ++ Q K++ WC H+IH + + V AQL
Sbjct: 534 KEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQL 593
Query: 1049 KDIM--VQQRMSLAS---CGTDWDIVRKCICAAYFHQAAKLKGIGEYVNI-RTGMPCHLH 1102
++++ ++Q+ G +++R+C+CA YF A+ + + G P H+H
Sbjct: 594 RELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVHIH 653
Query: 1103 PTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVKQAGKS----- 1157
P+S+L ++I++HE+++TTK Y + V + EW+ +L P + S
Sbjct: 654 PSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARR 713
Query: 1158 --RQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRS 1194
R++ RRR + + + + ++++ L+ ++ + +S
Sbjct: 714 EVREDARRRWTNKENVKQLKDGISKDVLKKMQRRNDDKS 752
>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
Length = 452
Score = 367 bits (942), Expect = e-101
Identities = 185/396 (46%), Positives = 273/396 (68%), Gaps = 19/396 (4%)
Query: 533 PIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMS 592
PI +++++ +RDNS +IV G TGSGKTTQL +YL+E G++ +GMIG TQPR+VAA+S
Sbjct: 54 PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAIS 113
Query: 593 VAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMD 652
VA+RV+EEM LG +VGY +RF+DC+S+ T IKYMTDG LL+ L + +L +S II+D
Sbjct: 114 VAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILD 173
Query: 653 EAHERSLNTDVLFGLLREVVA-----RRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGR 707
EAHER+L TD+LFGLL+++ R+ LK++V SATM+ K +AFFGN PIF IPGR
Sbjct: 174 EAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGR 233
Query: 708 TFPVDILFSKT--PQE----DYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIV 761
+PV F P++ Y++A VK ++ +HL+ GDIL+F+ GQ +IE + + +
Sbjct: 234 LYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLF 293
Query: 762 EHLEELEN--------APALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLT 813
+ E ++ L +LP Y + +D Q +IF P G+RKC+++TNI+ TSLT
Sbjct: 294 QMAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLT 353
Query: 814 VDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSA 873
+DGI +V+D G+ K NPR+G+D L++ PIS++ A QRSGRAGRT G+CFR+Y++
Sbjct: 354 IDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDF 413
Query: 874 YKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQF 909
+ + +PEI+RT+L +VVL LK L + D++++
Sbjct: 414 WNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapiens]
Length = 1143
Score = 352 bits (902), Expect = 2e-96
Identities = 201/550 (36%), Positives = 302/550 (54%), Gaps = 23/550 (4%)
Query: 519 FAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYG 578
F + + +R LPI +L ++++ +V+V G+TG GK+TQ+ QYL G++
Sbjct: 149 FGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH-- 206
Query: 579 MIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESL 638
+ CTQPRR+A +S+AKRV E G +VGY IRFE S T I ++T G+LLR+
Sbjct: 207 -VACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQ 265
Query: 639 READLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGN 698
RE L Y +I+DE HER L+ D L G+L+ ++ R DLK+I+ SAT++ F+++F N
Sbjct: 266 REPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYFSN 325
Query: 699 VPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHL-----------SGAPGDILIFM 747
P+ +PGR FP+ +++ E + K + L GD+L+F+
Sbjct: 326 APVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVFL 385
Query: 748 PGQEDIEVTSDQIVEHLEELENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNI 807
G +I + + + VLP++S L Q K+F AP GVRKCI++TNI
Sbjct: 386 SGMAEISAVLEAAQTYASHTQR---WVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNI 442
Query: 808 AETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFR 867
AETS+T+DGI FV+DSG K ++P+ + LQ + ISQA+A QR GRAGRTGPG CFR
Sbjct: 443 AETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFR 502
Query: 868 LYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQL 927
LY +S Y + VPEI+R L ++VL +KS+ V D F F++PPP ++ ++ L
Sbjct: 503 LYAESDY-DAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLETAILYL 561
Query: 928 WILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRP 987
GALD++ LT G L+ + P+D + KMLI+ +L I + LSV + F R
Sbjct: 562 RDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPFTRS 621
Query: 988 KGREEESDQIREKFAVPESDHLTYLNVYLQW-----KNNNYSTIWCNDHFIHAKAMRKVR 1042
E R + D T NV+ W + + S WC I + ++
Sbjct: 622 AQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYEMA 681
Query: 1043 EVRAQLKDIM 1052
+R Q K+++
Sbjct: 682 NLRRQFKELL 691
>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
sapiens]
Length = 743
Score = 349 bits (896), Expect = 8e-96
Identities = 199/648 (30%), Positives = 355/648 (54%), Gaps = 28/648 (4%)
Query: 525 ILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHE---DGYTDYGMIG 581
+L++R+ LPI+ + + + N IVIV G+ GK+ Q+ Q+ E + +G +
Sbjct: 55 LLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVI 114
Query: 582 CTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREA 641
CTQ + + +A RV++EM N+G EVGY I FE+C + T+++Y TD +L RE +
Sbjct: 115 CTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNP 174
Query: 642 DLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPI 701
L Y II+D+ HERS+ TDVL GLL++V+ R +LKLI+ S+ K +++GNVP+
Sbjct: 175 FLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPV 234
Query: 702 FHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIV 761
+ + PV++++ Q+D E+ ++ ++H SG GDI++F+ ++DIE + +
Sbjct: 235 IEVKNK-HPVEVVYLSEAQKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVY 293
Query: 762 EHLEELENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKC-------IVATNIAETSLTV 814
+ + L V+P+Y P + + +F+ + ++C ++ T+ E +
Sbjct: 294 QGSNLNPDLGELVVVPLY---PKE-KCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIWS 349
Query: 815 DGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAY 874
+ + FVID G + KV+NPRI ++L + PISQ+ A R G + G+ F LYT+
Sbjct: 350 NSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFA 409
Query: 875 KNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALD 934
++ E+Q NL ++VL +K + + L FM+ P ++++ ++ L L ALD
Sbjct: 410 SKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPAPESLMQALEDLDYLAALD 469
Query: 935 NTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIF-YRPKGREEE 993
N G L+ G +M EFPLDP LSK ++ SC+ C E+L I +M++ P F + P G EE
Sbjct: 470 NDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGAEEA 529
Query: 994 SDQIREKFAVPESDHLTYLNVYLQWKNNNYSTI-------WCNDHFIHAKAMRKVREVRA 1046
+ + F PE DH T +++Y +++ ++ WC D+F++ A+R +RA
Sbjct: 530 ALTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMADVIRA 589
Query: 1047 QLKDIMVQQRMSLA--SCGTDWDI--VRKCICAAYFHQAAK-LKGIGEYVNIRTGMPCHL 1101
+L +I+ + + A + G+ + ++K + + YF Q A+ + G G Y+ + L
Sbjct: 590 ELLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQL 649
Query: 1102 HPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFY 1149
HP S P+++++H+ ++ Y++ + + E +L P +Y
Sbjct: 650 HPLSGYSITKKMPEWVLFHKFSISENNYIRITSEISPELFMQLVPQYY 697
>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
sapiens]
Length = 717
Score = 295 bits (755), Expect = 2e-79
Identities = 202/644 (31%), Positives = 334/644 (51%), Gaps = 25/644 (3%)
Query: 525 ILEQRQYLPIFAVQQELLTIIRDN--SIVIVVGETGSGKTTQLTQYLHEDGYT---DYGM 579
+L+QRQ LPI+A + L + N +V+V GE GSGK+TQ+ Q+ E G
Sbjct: 38 LLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQKGQ 97
Query: 580 IGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLR 639
+ TQP +AA S+A RV++EM LG EVGY+I EDCT NTL+++ D +LL+E
Sbjct: 98 VTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLLQEVAS 157
Query: 640 EADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARR--SDLKLIVTSATMDAEKFAAFFG 697
+ +++DEA ERS+ +D L GLL++ + DL+++V + K AF+G
Sbjct: 158 TRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKLRAFWG 217
Query: 698 NVPIFHIPGRTF--PVDILFSKTPQEDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEV 755
N PI HIP P I + P D VEAA + L++ PGD+L+F+P +E+I +
Sbjct: 218 NPPIVHIPREPGERPSPIYWDTIPP-DRVEAACQAVLELCRKELPGDVLVFLPSEEEISL 276
Query: 756 TSDQIVEHLEEL--ENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLT 813
+ + +E L + P VLP++ +QA +++ RK +V +A+ S +
Sbjct: 277 CCESLSREVESLLLQGLPP-RVLPLHPDCGRAVQA-VYEDMD--ARKVVVTHWLADFSFS 332
Query: 814 VDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSA 873
+ I VIDSG V+NPRI + + PIS+ A R RA PG C LY +S
Sbjct: 333 LPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGFPPGSCLCLYPKSF 392
Query: 874 YKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGAL 933
+ E P + NL+++VLLLK + + + HF+D P + ++ ++ L L AL
Sbjct: 393 LELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFLDQPAPEALMQALEDLDYLAAL 452
Query: 934 DNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEE 993
D+ G L+ G ++ EFPL P L+K L+ SC+ C E+L + +ML+ F RP EE
Sbjct: 453 DDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPGFTRPPLSAEE 512
Query: 994 SDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIM- 1052
+ +R + DH + + VY + + WC ++ A+ + ++R +L ++M
Sbjct: 513 A-ALRRALEHTDGDHSSLIQVYEAFIQSGADEAWCQARGLNWAALCQAHKLRGELLELMQ 571
Query: 1053 -VQQRMSLASCGTDWD--IVRKCICAAYFHQAAK-LKGIGEYVNIRTGMPCHLHP---TS 1105
++ +SL + G++ + ++K + + YF + A+ G G Y+ + L
Sbjct: 572 RIELPLSLPAFGSEQNRRDLQKALVSGYFLKVARDTDGTGNYLLLTHKHVAQLSSYCCYR 631
Query: 1106 SLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFY 1149
S P +++YH ++ + V+ + + L EL P ++
Sbjct: 632 SRRAPARPPPWVLYHNFTISKDNCLSIVSEIQPQMLVELAPPYF 675
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 287 bits (735), Expect = 4e-77
Identities = 218/744 (29%), Positives = 368/744 (49%), Gaps = 110/744 (14%)
Query: 493 EDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVI 552
++ + D +QK + +++K + + R+ LP + +Q+EL+ +I ++ + +
Sbjct: 172 QENEPDGTLDQKLLEDLQKKKND----LRYIEMQHFREKLPSYGMQKELVNLIDNHQVTV 227
Query: 553 VVGETGSGKTTQLTQYLHEDGYTDYGM-----IGCTQPRRVAAMSVAKRVSEEMGGNLGE 607
+ GETG GKTTQ+TQ++ D Y + G I CTQPRR++A+SVA+RV+ E + G
Sbjct: 228 ISGETGCGKTTQVTQFIL-DNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGS 286
Query: 608 --EVGYAIRFED-CTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVL 664
GY IR + + I Y T GI+L+ + L S I++DE HER+L +DVL
Sbjct: 287 GNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVL 346
Query: 665 FGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPV------DIL---- 714
++++++ RSDLK+I+ SAT++AEKF+ +FGN P+ HIPG TFPV D++
Sbjct: 347 MTVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIR 406
Query: 715 -----------FSKTPQEDYVEAAVKQ---------------SLQVHLSGAPGDILIFMP 748
F + + +V K+ L+ S + D++ M
Sbjct: 407 YVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMM- 465
Query: 749 GQEDIEVTSDQIVEHLE----ELENAPALAVLP--------------------------- 777
ED +V + IV + E E+ L LP
Sbjct: 466 --EDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIP 523
Query: 778 IYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGM 837
++S +P+ Q ++F++ P GVRK ++ATNIAETS+T+D +++VID G K F+ + +
Sbjct: 524 LHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNI 583
Query: 838 DALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTT-TVPEIQRTNLANVVL 896
+ +S+ANA QR GRAGR PG C+ LY + + LL +PEI RT L + L
Sbjct: 584 STMSAEWVSKANAKQRKGRAGRVQPGHCYHLY--NGLRASLLDDYQLPEILRTPLEELCL 641
Query: 897 LLKSLGVQDLLQF--HFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPA 954
+K L + + F MDPP + +L S+ L L ALD LT G + P++P
Sbjct: 642 QIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPH 701
Query: 955 LSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAV-PESDHLTYLN 1013
+ KM++ C +L I + LS F P G+E+ +D R++ A SDHLT +N
Sbjct: 702 IGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVN 761
Query: 1014 VYLQW-----KNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWD- 1067
+ W + Y +C ++F+ + ++ + ++ Q + ++ + D +
Sbjct: 762 AFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPES 821
Query: 1068 --------IVRKCICAAYFHQAAKLK-GIGE-----YVNIRTGMPCHLHPTS-SLFGMGY 1112
I++ ICA + + AK++ +G+ V +T +HP S ++ +
Sbjct: 822 NINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDF 881
Query: 1113 TPDYIVYHELVMTTKEYMQCVTAV 1136
++++YH + T+ Y+ T V
Sbjct: 882 HYNWLIYHLKMRTSSIYLYDCTEV 905
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
Length = 1369
Score = 282 bits (721), Expect = 2e-75
Identities = 204/680 (30%), Positives = 337/680 (49%), Gaps = 102/680 (15%)
Query: 511 RKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLH 570
RK +++ ++ K +L++RQ LP+F + ++ ++ + +V+V GETGSGK+TQ+ +L
Sbjct: 554 RKLQSTPKYQK---LLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLL 610
Query: 571 EDGYTDYGM-----IGCTQPRRVAAMSVAKRVSEEMG-----GNLGEEVGYAIRFEDCTS 620
ED + I CTQPRR++A+S+A RV +E+G G GY IR E
Sbjct: 611 EDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRAC 670
Query: 621 ENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKL 680
E+T + Y T G+LLR+ + L + S +I+DE HERS+ +D L +L+E++ +RSDL L
Sbjct: 671 ESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHL 730
Query: 681 IVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDIL----------FSKTPQEDYVEAAVKQ 730
I+ SAT+D+EKF+ +F + PI I GR++PV++ F +Y + +++
Sbjct: 731 ILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEE 790
Query: 731 SLQVHL-------------------SGAPGDILIFMPG-----------QEDIEVTSDQI 760
+V + +GA D+ F ++ D I
Sbjct: 791 EEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLI 850
Query: 761 VEHLEELENAP--------ALAVLP-------IYSQLPSDL------------------- 786
+E L L+ +P L LP +Y L +D
Sbjct: 851 LELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQ 910
Query: 787 -QAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPI 845
QA F P GVRK ++ATNIAET +T+ ++FVID+G K ++ M +L +
Sbjct: 911 DQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFV 970
Query: 846 SQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLK--SLGV 903
S+A+A QR GRAGR G CFR+YT+ ++ + +VPEI R L + L + +LG
Sbjct: 971 SKASALQRQGRAGRVRDGFCFRMYTRERFEG-FMDYSVPEILRVPLEELCLHIMKCNLGS 1029
Query: 904 QDLLQFHFMDPPPEDNMLNSMYQLWILGALD-NTGGLTSTGRLMVEFPLDPALSKMLIVS 962
+ +DPP + N+M L +GA + N LT G+ + P++ + KMLI
Sbjct: 1030 PEDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFG 1089
Query: 963 CDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNN 1022
GC + + ++++ + F P GR++E+D + A+ +SDHLT N YL WK
Sbjct: 1090 AIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKAR 1149
Query: 1023 Y------STIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAA 1076
+C +F++ ++ + +V+ +L ++ S ++ T W+ R +
Sbjct: 1150 QEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLS 1209
Query: 1077 YFHQAAKLKGI---GEYVNI 1093
F + A LK + G Y N+
Sbjct: 1210 -FQEIALLKAVLVAGLYDNV 1228
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 271 bits (693), Expect = 3e-72
Identities = 212/730 (29%), Positives = 363/730 (49%), Gaps = 96/730 (13%)
Query: 493 EDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVI 552
++ + D +QK + +++K + + R+ LP + +Q+EL+ +I ++ + +
Sbjct: 172 QENEPDGTLDQKLLEDLQKKKND----LRYIEMQHFREKLPSYGMQKELVNLIDNHQVTV 227
Query: 553 VVGETGSGKTTQLTQYLHEDGYTDYGM-----IGCTQPRRVAAMSVAKRVSEEMGGNLGE 607
+ GETG GKTTQ+TQ++ D Y + G I CTQPRR++A+SVA+RV+ E + G
Sbjct: 228 ISGETGCGKTTQVTQFIL-DNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGS 286
Query: 608 --EVGYAIRFED-CTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVL 664
GY IR + + I Y T GI+L+ + L S I++DE HER+L +DVL
Sbjct: 287 GNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVL 346
Query: 665 FGLLREVVARRSDLKLIVTSATMDAEKFAAFFGN-----VPIFHIPGRTFPVDILFSKT- 718
++++++ RSDLK+I+ SAT++AEKF+ +FGN +P F P + ++ + K
Sbjct: 347 MTVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIR 406
Query: 719 -----------------------PQEDYVEAAVKQ-------SLQVHLSGAPGDILIFMP 748
+++ EA K+ L+ S + D++ M
Sbjct: 407 YVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMM- 465
Query: 749 GQEDIEVTSDQIVEHLE----ELENAPALAVLPIYSQLPS--DL-----------QAKIF 791
ED +V + IV + E E+ L LP + + + DL Q ++F
Sbjct: 466 --EDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSVNQTQVF 523
Query: 792 QKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANAN 851
++ P GVRK ++ATNIAETS+T+D +++VID G K F+ + + + +S+ANA
Sbjct: 524 KRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAK 583
Query: 852 QRSGRAGRTGPGQCFRLYTQSAYKNELLTT-TVPEIQRTNLANVVLLLKSLGVQDLLQF- 909
QR GRAGR PG C+ LY + + LL +PEI RT L + L +K L + + F
Sbjct: 584 QRKGRAGRVQPGHCYHLY--NGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFL 641
Query: 910 -HFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCS 968
MDPP + +L S+ L L ALD LT G + P++P + KM++ C
Sbjct: 642 SRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCL 701
Query: 969 SEILLIVSMLSVPAIFYRPKGREEESDQIREKFAV-PESDHLTYLNVYLQW-----KNNN 1022
+L I + LS F P G+E+ +D R++ A SDHLT +N + W +
Sbjct: 702 DPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFR 761
Query: 1023 YSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWD---------IVRKCI 1073
Y +C ++F+ + ++ + ++ Q + ++ + D + I++ I
Sbjct: 762 YEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVI 821
Query: 1074 CAAYFHQAAKLK-GIGE-----YVNIRTGMPCHLHPTS-SLFGMGYTPDYIVYHELVMTT 1126
CA + + AK++ +G+ V +T +HP S ++ + ++++YH + T+
Sbjct: 822 CAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTS 881
Query: 1127 KEYMQCVTAV 1136
Y+ T V
Sbjct: 882 SIYLYDCTEV 891
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 [Homo
sapiens]
Length = 1155
Score = 251 bits (640), Expect = 4e-66
Identities = 177/577 (30%), Positives = 305/577 (52%), Gaps = 41/577 (7%)
Query: 511 RKSEASSEFAKKKS-ILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYL 569
R S++ E +++ + ++ LP+ + +L I + +V++ G+TG GKTT++ Q L
Sbjct: 373 RLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLL 432
Query: 570 HEDGYTDYGMIGC----TQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCT-SENTL 624
E T+ C TQPRR++A+SVA+RVS E+G +L VG+ +R E S
Sbjct: 433 LERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGA 492
Query: 625 IKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTS 684
+ + T GILLR+ L+ S +I+DE HER +NTD L LL+ + L+L++ S
Sbjct: 493 LLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMS 552
Query: 685 ATMDAEKFAAFFGNVPIFHIPGRTFPV------DILFS-------------KTPQEDYVE 725
AT D E+F+ +FG P+ +PG +PV DIL ++ E ++
Sbjct: 553 ATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALD 612
Query: 726 AAVKQSLQVHLS--GAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYSQLP 783
+ L +H+ G PG IL F+PG ++I+ ++ E L E+ +LP++S +P
Sbjct: 613 LDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESK--YLILPVHSNIP 670
Query: 784 SDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIY 843
Q IFQ+ P GVRK ++ATNIAETS+T++ I+ V+DSG K + ++ + + L+
Sbjct: 671 MMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETV 730
Query: 844 PISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLK-SLG 902
+S+AN QR GRAGR G + L+ +S + +++ VPEI RT L N+VL K +
Sbjct: 731 WVSRANVIQRRGRAGRCQSGFAYHLFPRSRLE-KMVPFQVPEILRTPLENLVLQAKIHMP 789
Query: 903 VQDLLQF--HFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI 960
+ ++F +D P + ++ L +G LD LT+ G+ + DP L+K ++
Sbjct: 790 EKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIV 849
Query: 961 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPE-SDHLTYLNV----- 1014
++ C +L++VS L+ F E D+++ + SDHL ++
Sbjct: 850 LAAIFRCLHPLLVVVSCLTRDP-FSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWE 908
Query: 1015 -YLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKD 1050
L+W++ + + ++ ++A ++R + + Q +
Sbjct: 909 EVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSE 945
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 [Homo
sapiens]
Length = 1194
Score = 251 bits (640), Expect = 4e-66
Identities = 177/577 (30%), Positives = 305/577 (52%), Gaps = 41/577 (7%)
Query: 511 RKSEASSEFAKKKS-ILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYL 569
R S++ E +++ + ++ LP+ + +L I + +V++ G+TG GKTT++ Q L
Sbjct: 412 RLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLL 471
Query: 570 HEDGYTDYGMIGC----TQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCT-SENTL 624
E T+ C TQPRR++A+SVA+RVS E+G +L VG+ +R E S
Sbjct: 472 LERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGA 531
Query: 625 IKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTS 684
+ + T GILLR+ L+ S +I+DE HER +NTD L LL+ + L+L++ S
Sbjct: 532 LLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMS 591
Query: 685 ATMDAEKFAAFFGNVPIFHIPGRTFPV------DILFS-------------KTPQEDYVE 725
AT D E+F+ +FG P+ +PG +PV DIL ++ E ++
Sbjct: 592 ATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALD 651
Query: 726 AAVKQSLQVHLS--GAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYSQLP 783
+ L +H+ G PG IL F+PG ++I+ ++ E L E+ +LP++S +P
Sbjct: 652 LDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESK--YLILPVHSNIP 709
Query: 784 SDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIY 843
Q IFQ+ P GVRK ++ATNIAETS+T++ I+ V+DSG K + ++ + + L+
Sbjct: 710 MMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETV 769
Query: 844 PISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLK-SLG 902
+S+AN QR GRAGR G + L+ +S + +++ VPEI RT L N+VL K +
Sbjct: 770 WVSRANVIQRRGRAGRCQSGFAYHLFPRSRLE-KMVPFQVPEILRTPLENLVLQAKIHMP 828
Query: 903 VQDLLQF--HFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI 960
+ ++F +D P + ++ L +G LD LT+ G+ + DP L+K ++
Sbjct: 829 EKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIV 888
Query: 961 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPE-SDHLTYLNV----- 1014
++ C +L++VS L+ F E D+++ + SDHL ++
Sbjct: 889 LAAIFRCLHPLLVVVSCLTRDP-FSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWE 947
Query: 1015 -YLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKD 1050
L+W++ + + ++ ++A ++R + + Q +
Sbjct: 948 EVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSE 984
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 221 bits (564), Expect = 3e-57
Identities = 171/598 (28%), Positives = 291/598 (48%), Gaps = 74/598 (12%)
Query: 532 LPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYL--HEDGYTDYGMIGCTQPRRVA 589
LPI ++E++++I NS+VI+ G TGSGK+TQL QY+ H + Y I TQPR++
Sbjct: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIVVTQPRKIG 191
Query: 590 AMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAI 649
A S+A+ +S+E LG VGY + E +E+T + YMT G+LL++ + L ++ I
Sbjct: 192 ASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTHI 251
Query: 650 IMDEAHERSLNTDVLFGLLREVVARRSD-LKLIVTSATMDAEKFAAFFGNVP-------- 700
I+DE HER+ D L ++R+++ S +K+++ SAT+ ++FA +F VP
Sbjct: 252 IIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFA-VPVQNKMNPA 310
Query: 701 -IFHIPGRTFPVD------------------ILFSKTPQEDYVEAAV-----------KQ 730
IF + G+ V+ +L +D E AV K+
Sbjct: 311 YIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDDLDMKE 370
Query: 731 SLQVHLSGAP-----GDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYSQLPSD 785
S SGA +L+F+PG +I + + + + L V P++S + +
Sbjct: 371 SGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHK-----RLQVYPLHSSVALE 425
Query: 786 LQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPI 845
Q +F G RK I++TNIAE+S+TV + +VID + V + +L++
Sbjct: 426 EQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWA 485
Query: 846 SQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLK--SLGV 903
S+ + NQR GRAGR G C+RL + + N + VPE+ R L + +L +K +G
Sbjct: 486 SKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGE 545
Query: 904 QDLLQFHFMDPPPEDNMLNSMYQLWILGAL----------DNTGGLTSTGRLMVEFPLDP 953
L + PP ++ ++ L +GAL + G LT GR++ + P++
Sbjct: 546 PRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQ 605
Query: 954 ALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFA-VPESDHLTYL 1012
L K++++ GC E L+I + LS+ F P + + + + F+ +SD + +
Sbjct: 606 QLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIALV 665
Query: 1013 NVYLQWKNNNYS---------TIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLAS 1061
+ WK + W ++I K +R+V E+ +LK + Q M + S
Sbjct: 666 EAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNMHVDS 723
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 186 bits (472), Expect = 1e-46
Identities = 128/468 (27%), Positives = 232/468 (49%), Gaps = 59/468 (12%)
Query: 722 DYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEH-LEELENAPALAVLPIYS 780
+ +EA ++ + S PG IL+F+PG +I++ +Q+ + L + + P++S
Sbjct: 829 ELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHS 888
Query: 781 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL 840
L S+ Q +F K P GV K I++TNIAETS+T+D +++VIDSG K K ++ GM++L
Sbjct: 889 SLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESL 948
Query: 841 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS 900
+ +SQANA QR GRAGR G CF L+T Y ++LL +PEIQR L + L +K
Sbjct: 949 EDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKI 1008
Query: 901 L------GVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPA 954
L +Q + ++PP D++ S +L LGAL LT G + P+D
Sbjct: 1009 LEMFSAHNLQSVFS-RLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVR 1067
Query: 955 LSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNV 1014
+ K+++ C L I + L+ + F P ++EE++Q + +FA SD+L L
Sbjct: 1068 IGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQA 1127
Query: 1015 YLQWKNNNYSTI-----WCNDHFIHAKAMRKVREVRAQLKDIM--------------VQQ 1055
Y W+ + + +C +F+ + ++++ ++ Q +++ +++
Sbjct: 1128 YKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEK 1187
Query: 1056 RMS-----LASCGTDWD-------IVRKCICAAYFHQAAKLKG-IGEYVNIRTGMP---- 1098
R L + G + + ++ +CAA + ++K G++ TG
Sbjct: 1188 RAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQP 1247
Query: 1099 --------------CHLHPTSSLFGM-GYTPDYIVYHELVMTTKEYMQ 1131
H+HP+S + + + Y++YHE + T++ +++
Sbjct: 1248 KSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIR 1295
Score = 162 bits (411), Expect = 1e-39
Identities = 90/229 (39%), Positives = 143/229 (62%), Gaps = 12/229 (5%)
Query: 496 KVDYRTEQKFADHMK-----RKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSI 550
+ D++ + A++ K R +AS +F +SIL++RQ LP + ++ +L ++R + +
Sbjct: 506 RYDWQAKSVHAENGKICKQFRMKQASRQF---QSILQERQSLPAWEERETILNLLRKHQV 562
Query: 551 VIVVGETGSGKTTQLTQYLHEDGYTD----YGMIGCTQPRRVAAMSVAKRVSEEMGGNLG 606
V++ G TG GKTTQ+ Q++ +D I CTQPRR++A+SVA+RV++E +G
Sbjct: 563 VVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPRRISAISVAERVAKERAERVG 622
Query: 607 EEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFG 666
VGY IR E S T + Y T G+LLR + L S II+DE HER+ +D L
Sbjct: 623 LTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLL 682
Query: 667 LLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILF 715
+L+++V++R L++I+ SAT++AE F+ +F + P+ IPGRTFPVD F
Sbjct: 683 VLKDIVSQRPGLQVILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFF 731
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens]
Length = 1157
Score = 183 bits (465), Expect = 8e-46
Identities = 131/436 (30%), Positives = 218/436 (50%), Gaps = 56/436 (12%)
Query: 765 EELENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSG 824
E+ + + L VLP+YS L + QA++F+ P+G R C+VATN+AETSLT+ GI +V+D G
Sbjct: 580 EQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCG 639
Query: 825 YCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVP 884
K + ++ G+ + ++ +SQA+A+QR+GRAGRT PG C+RLY+ SA + P
Sbjct: 640 KVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYS-SAVFGDFEQFPPP 698
Query: 885 EIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDN--------- 935
EI R + +++L +K+L V+ ++ F F PP + +L + L LGAL
Sbjct: 699 EITRRPVEDLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQ 758
Query: 936 ------TGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFY---R 986
+ +T+ GR M FP+ P +KML +S GC + IV+ ++V +F R
Sbjct: 759 LQENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDR 818
Query: 987 PKGREEESDQIREKFA---------------VPESDHLTYLNVYLQWKNNNYSTIWCNDH 1031
P +EE +++ K A + D + L + + + +C +
Sbjct: 819 PAASDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEAN 878
Query: 1032 FIHAKAMRKVREVRAQL----------KDIMVQQRMSLASCGTDWDIVRKCICAAYFHQA 1081
+ KAM ++R +R QL ++ V +M + +R+ + A
Sbjct: 879 GLRYKAMMEIRRLRGQLTTAVNAVCPEAELFVDPKMQ-PPTESQVTYLRQIVTAGLGDHL 937
Query: 1082 AKL---------KGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQC 1132
A+ K Y P +HP+S LF P+++VY E+V TTK YM+
Sbjct: 938 ARRVQSEEMLEDKWRNAYKTPLLDDPVFIHPSSVLF--KELPEFVVYQEIVETTKMYMKG 995
Query: 1133 VTAVDGEWLAELGPMF 1148
V++V+ +W+ L P +
Sbjct: 996 VSSVEVQWIPALLPSY 1011
Score = 175 bits (444), Expect = 2e-43
Identities = 101/238 (42%), Positives = 153/238 (64%), Gaps = 13/238 (5%)
Query: 527 EQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYT-DYGMIGCTQP 585
E+R LPI + +Q ++ + ++ IVIV GETGSGKTTQ+ Q+L+E G++ + +IG T+P
Sbjct: 247 EERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSIIGVTEP 306
Query: 586 RRVAAMSVAKRVSEEMGGNLGEEV-GYAIRFEDCTSENTLIKYMTDGILLRESLREADLD 644
RRVAA+++++RV++EM NL + V Y IR+E +E T IK+MTDG+LL+E ++ L
Sbjct: 307 RRVAAVAMSQRVAKEM--NLSQRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLL 364
Query: 645 HYSAIIMDEAHERSLNTDVLFGLLREVVARRS----DLKLIVTSATMDAEKFA----AFF 696
Y +I+DEAHERS+ TD+L GLL +V R+ LKL++ SAT+ E F F
Sbjct: 365 RYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFA 424
Query: 697 GNVPIFHIPGRTFPVDILFSK-TPQEDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDI 753
P+ + R FPV + F+K TP EDY ++ ++H G IL+F+ GQ ++
Sbjct: 425 KPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQAEV 482
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
Length = 1270
Score = 157 bits (397), Expect = 6e-38
Identities = 111/347 (31%), Positives = 174/347 (50%), Gaps = 22/347 (6%)
Query: 717 KTPQEDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELEN--APALA 774
+TP E +EA +K + PG +L+F+PG I +HLE + +
Sbjct: 631 ETPFE-LIEALLKY---IETLNVPGAVLVFLPGWNLIYTMQ----KHLEMNPHFGSHRYQ 682
Query: 775 VLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPR 834
+LP++SQ+P + Q K+F P GV K I++TNIAETS+T++ +++VIDS K+K+F
Sbjct: 683 ILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAH 742
Query: 835 IGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANV 894
M S+ N QR GRAGR PG CF L +++ ++ L T PE+ RT L +
Sbjct: 743 NNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFE-RLETHMTPEMFRTPLHEI 801
Query: 895 VLLLKSLGVQDLLQF--HFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLD 952
L +K L + + QF ++PPP D ++ + + L L ALD LT GR++ + P++
Sbjct: 802 ALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIE 861
Query: 953 PALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPE-SDHLTY 1011
P KM+I+ C I I + P F R I FA SDH+
Sbjct: 862 PRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKR---LGYIHRNFAGNRFSDHVAL 918
Query: 1012 LNVYLQWKN-----NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMV 1053
L+V+ W + +C ++ +R E + QLK+I++
Sbjct: 919 LSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILI 965
Score = 145 bits (366), Expect = 2e-34
Identities = 85/231 (36%), Positives = 138/231 (59%), Gaps = 12/231 (5%)
Query: 493 EDGKVDYRTEQKFADHMKRKSEASSEFAKK---KSILEQRQYLPIFAVQQELLTIIRDNS 549
++G + + T ++ + M K+E + + ++IL++R+ LP+ + E+L I NS
Sbjct: 348 DEGPLAFATPEQIS--MDLKNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNS 405
Query: 550 IVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGC----TQPRRVAAMSVAKRVSEEMGGNL 605
+VI+ G TG GKTTQ+ Q++ +D + C TQPRR++A+SVA+RV+ E G
Sbjct: 406 VVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEP 465
Query: 606 GEEVGYAIRFEDCTSE-NTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVL 664
G+ GY++RFE + I + T G+LLR+ EA + S +I+DE HER +NTD L
Sbjct: 466 GKSCGYSVRFESILPRPHASIMFCTVGVLLRKL--EAGIRGISHVIVDEIHERDINTDFL 523
Query: 665 FGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILF 715
+LR+VV ++++++ SAT+D F +F N PI + GRT+PV F
Sbjct: 524 LVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYF 574
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 157 bits (396), Expect = 8e-38
Identities = 82/191 (42%), Positives = 128/191 (67%), Gaps = 5/191 (2%)
Query: 529 RQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGM---IGCTQP 585
RQ LP+F Q+E++ II++N +V++VGETGSGKTTQ+ Q+L +D + + G+ I CTQP
Sbjct: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKN-GIPCRIFCTQP 248
Query: 586 RRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLR-EADLD 644
RR+AA++VA+RV+ E +G+ +GY IR E S TL+ + T+G+LLR + ++ L
Sbjct: 249 RRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLS 308
Query: 645 HYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHI 704
+ +I+DE HER +D L LR+++ + LKLI++SA +D F +FG+ P+ +I
Sbjct: 309 TVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYI 368
Query: 705 PGRTFPVDILF 715
GR F V +F
Sbjct: 369 QGRPFEVKEMF 379
Score = 150 bits (378), Expect = 9e-36
Identities = 102/319 (31%), Positives = 169/319 (52%), Gaps = 12/319 (3%)
Query: 741 GDILIFMPGQEDIEVTSDQIV-EHLEELENAPALAVLPIYSQLPSDLQAKIFQKAPDGVR 799
G +LIF+PG ++I D+I+ + +N V ++S + + Q K+ + P GVR
Sbjct: 623 GAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVR 682
Query: 800 KCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGR 859
K I++TNIAETS+TV+ ++FVIDSG K K F+ + L++ IS+A+A QR GRAGR
Sbjct: 683 KIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGR 742
Query: 860 TGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFM----DPP 915
PG CFRL+++ ++N +L PE+ R L + L K L + F+ +PP
Sbjct: 743 CRPGICFRLFSRLRFQN-MLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPP 801
Query: 916 PEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIV 975
P + N++ L + A+D LT G + + P++P L KM++ + + C IL I
Sbjct: 802 PALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIA 861
Query: 976 SMLSVPAIFYRPKGREEESDQI--REKF-AVPESDHLTYLNVYLQW---KNNNYSTIWCN 1029
L+ F P ++ + R++F A SDH+ L + W +++ + +C
Sbjct: 862 CTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCE 921
Query: 1030 DHFIHAKAMRKVREVRAQL 1048
+F+ M + +R QL
Sbjct: 922 KNFLSQATMEIIIGMRTQL 940
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 80.5 bits (197), Expect = 9e-15
Identities = 79/342 (23%), Positives = 142/342 (41%), Gaps = 27/342 (7%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
+ +ERE + D E ++ + + E ++ +++ E G D+ R+ R A E
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETEREGER-GRDRQTDGQRERERQRDAEKER 159
Query: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRD------ 171
+ ER+RQ+ERER ++ +E + K+ K+ DR +R R+R+
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
Query: 172 -----------ERDRSRHSSR-----SERDGGSERSSRRNEPESPRHRPKDAATPSRSTW 215
ERDR R + R +ER+ SER + R++ E R R +D R
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDK-ERERERDRDRDRDRRQKE 278
Query: 216 EEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYN 275
E + RR++ + + R ER R R+R R + + + +
Sbjct: 279 RERQTDRKRQRRTERDRETERKRERQRER-ERERERNRKRERERERERERERQRETERDR 337
Query: 276 EWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDE 335
E +R+ T + R R R+ E + E ER++ D Q +R+ D D
Sbjct: 338 EKERERKRKRQT-EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396
Query: 336 FHNPLAYSSEDYVRRREQHLHKQKQK-RISAQRRQINEDNER 376
+ +D +RE ++++K R S + R+ + E+
Sbjct: 397 QKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREK 438
Score = 79.0 bits (193), Expect = 3e-14
Identities = 78/305 (25%), Positives = 126/305 (41%), Gaps = 45/305 (14%)
Query: 60 REREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHY--------- 110
+ERE + D E +++++ + K+ E K+ Q+ E E + +N +DRH
Sbjct: 157 KERERQTDRERQRQTERNRQKEREREKNRQERRERER-QREKENKTEDRHSERGRERERE 215
Query: 111 RSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKE-EKDWKKEKSRDRDYDRKRD 169
R ET E +R +RERE++ AS +E E+D ++E+ RDRD DR R
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Query: 170 RDERDRS---RHSSRSERDGGSERS-------------SRRNEPESPRHRPKDAATPSRS 213
+ ER+R + R+ERD +ER +R+ E E R R ++ +
Sbjct: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335
Query: 214 TWEEE-----------------DSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRS 256
E+E +G R+++ E R S R RDRDR
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 257 VRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQWE 316
+ + T + E +R + R R RGR E ++G D E + +
Sbjct: 396 RQKERERQTEKDRDGQRETEKQREREKDRESER-GRERGREREKQKGRERDRERQTDRQA 454
Query: 317 DDQRQ 321
QR+
Sbjct: 455 GRQRK 459
Score = 77.0 bits (188), Expect = 1e-13
Identities = 69/322 (21%), Positives = 135/322 (41%), Gaps = 28/322 (8%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
++RER + D K+ +D E+ ++ Q D E + + +N +K+R + R
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETER--- 133
Query: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSR 177
G + +R R+R+R+ + + +E + ++ R+R +R+R+++ ++R
Sbjct: 134 EGERGRDRQTDGQRERERQRDAEKERERQTDRERQ---RQTERNRQKEREREKNRQERRE 190
Query: 178 HSSRSERDGGSERSSRRNEPESPRHRPKDAATP-SRSTWEEEDSGYGSSRRSQWESPSPT 236
+ E++ +E E R R + T R T E D + R + ++
Sbjct: 191 RERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERER 250
Query: 237 PSYRDSER-SHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRG 295
S R++ER R RDRDR R + + T + DR + + R R
Sbjct: 251 ASERETERDKERERERDRDRD-RDRRQKERERQTDRKRQRRTERDRE---TERKRERQRE 306
Query: 296 RREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHL 355
R E E + E ER++ + QR+ +RD + R+R+ +
Sbjct: 307 RERERERNRKRERERERERERERQRETERD---------------REKERERKRKRQTEM 351
Query: 356 HKQKQKRISAQ-RRQINEDNER 376
+++ ++ + RRQ + ER
Sbjct: 352 DRERNRQTGREGRRQAERERER 373
Score = 76.3 bits (186), Expect = 2e-13
Identities = 75/323 (23%), Positives = 128/323 (39%), Gaps = 33/323 (10%)
Query: 90 KDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSK 149
KDA+ GD +N +K+R R + +T E E+ R R+R+R
Sbjct: 47 KDAD---GDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRH--------- 94
Query: 150 EEKDWKKEKSRDRDYDRKRDRD---ERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKD 206
E+ +EK R+R DR+RDR ER+R + R G R+ + + R R +D
Sbjct: 95 RERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRD 154
Query: 207 AATP-SRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDR-SVRGKYSD- 263
A R T E +R+ + E R+ ER + DR S RG+ +
Sbjct: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214
Query: 264 --DTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQ 321
+T T + + DR+ + R R ++ E E +TE ++++ + R
Sbjct: 215 ERETETETERKRQTDRERDRQR-----KTEREREKQAERERASERETERDKERERERDRD 269
Query: 322 ADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINEDNERWETNR 381
DRD + + RR E+ ++++ +R + E N + E R
Sbjct: 270 RDRDRRQKERE--------RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER 321
Query: 382 MLTSGVVHRLEVDEDFEEDNAAK 404
+ E + D E++ K
Sbjct: 322 ERERERERQRETERDREKERERK 344
Score = 57.8 bits (138), Expect = 6e-08
Identities = 60/247 (24%), Positives = 103/247 (41%), Gaps = 35/247 (14%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
++RERE + + K++ + ++ E ++ ++D E+E + + DR R
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE----RNRQ 358
Query: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKR----DRDER 173
G R +RERER S++E ++ ++++ RDR +R+R DRD +
Sbjct: 359 TGREG-------RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQ 411
Query: 174 DRSRHSSRSERDGGSERSSRR-NEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWES 232
+ E+D SER R E E + R +D R + +G R + + +
Sbjct: 412 RETEKQREREKDRESERGRERGREREKQKGRERD-----RERQTDRQAGRQRKRSTLYVN 466
Query: 233 PSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSR 292
P P + +S R +R K S + P + A R G + SR
Sbjct: 467 PPPRTARSGVVQS---DPNRPTRGIRWKSSPEDP---------KAASTRFPWGRPAKASR 514
Query: 293 GR--GRR 297
GR GRR
Sbjct: 515 GRVAGRR 521
Score = 52.0 bits (123), Expect = 3e-06
Identities = 60/244 (24%), Positives = 90/244 (36%), Gaps = 15/244 (6%)
Query: 139 RREHGVYASSKEEKDWKKEKSRDRDYDRKRDRD-ERDRSRHSSRSERDGGSERSSRRNEP 197
RR G S + + K D D DR+R+R ER+R R ++ER+ +R RR
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGD-DRERNRQKERERRREKRQTERETDRKRERRR--- 83
Query: 198 ESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSV 257
E RHR +D + E+E R + + R R RDR
Sbjct: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143
Query: 258 RGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQ---- 313
G+ + + K E DR T R R + E E+ E ERQ
Sbjct: 144 DGQRERER--QRDAEKERERQTDRERQRQT---ERNRQKEREREKNRQERRERERQREKE 198
Query: 314 -QWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINE 372
+ ED + R+ E E E +R+ + +++ +R A R+
Sbjct: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
Query: 373 DNER 376
D ER
Sbjct: 259 DKER 262
Score = 39.3 bits (90), Expect = 0.023
Identities = 45/225 (20%), Positives = 87/225 (38%), Gaps = 16/225 (7%)
Query: 153 DWKKEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSR 212
D+ + + ++ R+R + + ER+ ER RR + ++ R + R
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDR-----KR 79
Query: 213 STWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSY 272
E+D R + + R+ ER R + R+RDR + + +
Sbjct: 80 ERRREKDRHRKRDRHRERQRD------REKER-ERQTDRERDRQREKERNRQKERERETE 132
Query: 273 KYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEG 332
+ E DR+ G + R R R E E D E +RQ + Q++ +R+ +
Sbjct: 133 REGERGRDRQTDG---QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
Query: 333 YDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQR-RQINEDNER 376
E +ED R + ++++ +R RQ + + +R
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 77.8 bits (190), Expect = 6e-14
Identities = 81/377 (21%), Positives = 153/377 (40%), Gaps = 46/377 (12%)
Query: 28 KSKSAASEQHVFKAPAPRPSLLGLDLLASLKRREREEKDDGEDKKKSKVSSYKDWEESKD 87
+ K ++ +F+ P L+ L+ E ++D D ++S ++D + +
Sbjct: 234 RKKKKEKKEDIFRR-FPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLE 292
Query: 88 DQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYAS 147
++K +E+ Q I K+R R E E ER R+RERER
Sbjct: 293 EEKGKKEK----ERQEIEKERRERERERER-------ERERREREREREREREREKEKER 341
Query: 148 SKE-----EKDWKKEKSRDRDYDRKRDRD---------ERDRSRHSSRS---------ER 184
+E ++D KE+ RDRD +R RDRD +R RSR SR ER
Sbjct: 342 ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERER 401
Query: 185 DGGSERS-SRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDS- 242
+ ER R E E R R ++ + EE++ R+ + + +Y++
Sbjct: 402 EREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERL 461
Query: 243 ---ERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRG---R 296
E R TR+ ++ + + + + E+ +D P+ RG R
Sbjct: 462 KNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKR 521
Query: 297 REEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLH 356
+ E+ + D + +++ E+ + R ++ EG+ + L ++ RRR+ +
Sbjct: 522 LRDREKEMEADERDRKREKEELEEIRQR---LLAEGHPDPDAELQRMEQEAERRRQPQIK 578
Query: 357 KQKQKRISAQRRQINED 373
++ + + +Q E+
Sbjct: 579 QEPESEEEEEEKQEKEE 595
Score = 53.1 bits (126), Expect = 2e-06
Identities = 77/369 (20%), Positives = 142/369 (38%), Gaps = 58/369 (15%)
Query: 53 LLASLKRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRS 112
LL + + + + D+ + KKK+ + + + DD++ +EE R+D+ +
Sbjct: 157 LLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEE-------TKRRDQMIKG 209
Query: 113 ARV----ETPSHPGGVSEEFWERSRQRERERRE-------------------HGVYASSK 149
A E S S+E R++++E++E + A
Sbjct: 210 AIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEM 269
Query: 150 EEKD---WKKEKSRDRDYDRK---------RDRDERDRSRHSSRSERDGGSERSSRRNEP 197
EE +E S+ RD +K ++R E ++ R ER+ ER R E
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERER 329
Query: 198 ESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSV 257
E R R K+ R E D ++ + RD ERS S R++DRS
Sbjct: 330 EREREREKE---KERERERERDRDRDRTKERDRDRDRERDRDRDRERS---SDRNKDRSR 383
Query: 258 RGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQWED 317
+ S D + E +R R R R E E D + +R++ E+
Sbjct: 384 SREKSRDRERERERERERERERERER-----EREREREREREREREREKDKKRDREEDEE 438
Query: 318 D---QRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKR--ISAQRRQINE 372
D +R+ +R + Y E R E+ +++++R ++ + +++ E
Sbjct: 439 DAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKE 498
Query: 373 DNERWETNR 381
E ++ +R
Sbjct: 499 FLEDYDDDR 507
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 77.8 bits (190), Expect = 6e-14
Identities = 102/482 (21%), Positives = 197/482 (40%), Gaps = 54/482 (11%)
Query: 60 REREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPS 119
R E + D D ++ + + +D E +D +++ E E + + K+R R
Sbjct: 659 RREERRVDRVDDRRDERARERDRERERDRERERERER--ERDREREKERELERERAR--- 713
Query: 120 HPGGVSEEFWERSRQRERER---REHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRS 176
E ER ++R+RER R+H +++ ++E+ RDR+ +R+R+R+ER+R
Sbjct: 714 ------EREREREKERDRERDRDRDH--------DRERERERERDREKEREREREERERE 759
Query: 177 RHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWE----- 231
R R ER+ R E E R R +D + WE++D G R + E
Sbjct: 760 RERER-ERE-------RERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDR 811
Query: 232 SPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLS 291
+P R S++ +R R + + +P + +Y + +++ L LS
Sbjct: 812 NPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSP-DSDAYNSGDDKNEKHRL-----LS 865
Query: 292 RGRGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRR 351
+ +E S TE+ + +W+++ R+ +R Y+E SS D R +
Sbjct: 866 QVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERK--ESSRRYEEQELKEKVSSVDKQREQ 923
Query: 352 EQHLHKQKQKRISAQRRQINEDNERWET--NRMLTSGVVHRLEVDEDFEEDNAAKVHLMV 409
+ L + + +ED E + + + + + + E+D V +
Sbjct: 924 TEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDD----VGIER 979
Query: 410 HNLVPPFLDGRIVFTKQPEPVIPV----KDATSDLAIIARKGSQTVRKHREQKERK-KAQ 464
N+ DG++ K+ + + K + D I + +Q +K R + +
Sbjct: 980 GNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTK 1039
Query: 465 HKHWELAGTKLGDIMGVKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKS 524
+ E+ K G + +K+E+ + D V RTE A+H + S + S
Sbjct: 1040 EELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSS 1099
Query: 525 IL 526
+L
Sbjct: 1100 LL 1101
Score = 70.9 bits (172), Expect = 7e-12
Identities = 119/516 (23%), Positives = 191/516 (37%), Gaps = 99/516 (19%)
Query: 70 DKKKSKVSSYKDWE-ESKDDQKDA--EEEGGDQA---------GQNIRKDRHYRSARVET 117
D S + + WE S ++D E + DQA G+ R+D R R +
Sbjct: 584 DSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSS 643
Query: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRD-ERDRS 176
P G ++E ER +RE ERR V D + E++R+RD +R+RDR+ ER+R
Sbjct: 644 PIRHQGRNDEL-ERDERRE-ERRVDRV-------DDRRDERARERDRERERDRERERERE 694
Query: 177 RHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPT 236
R R R E E R + +D E D R + E
Sbjct: 695 RERDREREKERELERERAREREREREKERD---------RERDRDRDHDRERERERERDR 745
Query: 237 PSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGR 296
R+ ER R R+R+R R R R
Sbjct: 746 EKEREREREERERERERER-----------------------------------ERERER 770
Query: 297 REEGEEGISFDTEEERQQ-WED-----DQRQADRDWYMMD----EGYDEFHNPLAYSSED 346
E E D E ERQ+ WED D R+ R+ D +G+DE + Y +E
Sbjct: 771 ERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEG 830
Query: 347 YVRRREQHLHKQKQKRISAQRRQINEDNERWETNRMLTSGV---VHRLEVDEDFEEDNAA 403
R+ ++++ S N +++ E +R+L+ V R ED
Sbjct: 831 SPSPRQS---PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQG 887
Query: 404 KVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAII--ARKGSQTVRKHREQKERK 461
+ R + E V V I+ +R +Q + H + ++R+
Sbjct: 888 RWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRE 947
Query: 462 KAQHKHWELAGTKLGDIMGVKKEEEPD--------KAVTEDGKV--DYRTEQKFADHMKR 511
+ H E +KK++E D + +EDG+V + ++K + KR
Sbjct: 948 TSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKR 1007
Query: 512 K-----SEASSEFAKKKSILEQRQYLPIFAVQQELL 542
K S+ S E A ++S ++ P ++EL+
Sbjct: 1008 KKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELV 1043
Score = 62.0 bits (149), Expect = 3e-09
Identities = 90/403 (22%), Positives = 145/403 (35%), Gaps = 64/403 (15%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
+R ER E G+ ++ +++E+ + +D ++ + G++ R R R R
Sbjct: 412 RRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELR 471
Query: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRD------------RDYD 165
S S E + SR +E R+ S+++ D++ + RD R Y
Sbjct: 472 DSRDMRDSREMRDYSRDT-KESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYG 530
Query: 166 RKRDRDE------RDRSRHSSRSE----------------RDGGSERS------------ 191
R R+E R+ SR+ SRSE + GS S
Sbjct: 531 RNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNS 590
Query: 192 -------SRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSER 244
+R + PE R+ +D +R + E G R ++ P+ R R
Sbjct: 591 NYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGR 650
Query: 245 SHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPR-LSRGRGRREEGEEG 303
+ L +R R DD + E DR R R R + E E
Sbjct: 651 NDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERE 710
Query: 304 ISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRI 363
+ + E ER++ D +R DRD E E E R RE+ +++++
Sbjct: 711 RAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERER 770
Query: 364 SAQRRQINE-DNER-----WETNRMLTSGVVHRLEVDEDFEED 400
+R + E D ER WE G R E E+ ED
Sbjct: 771 ERERERARERDKERERQRDWEDK---DKGRDDRREKREEIRED 810
Score = 57.8 bits (138), Expect = 6e-08
Identities = 101/435 (23%), Positives = 160/435 (36%), Gaps = 75/435 (17%)
Query: 29 SKSAASEQHVFKAPAPRPSLLGLDLLASLKRREREEKDDGEDKKKSKVSSYKDWE---ES 85
SK+ S++ + P+P P + L + + + KD E+K + +D+E E
Sbjct: 251 SKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREK 310
Query: 86 KDDQKDAEEEG-------------GDQAGQNI-RKDRHYRSARVETPSHPGGVSEEFWE- 130
+D + G Q+G +I R R R +PS+ ++
Sbjct: 311 RDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRS 370
Query: 131 ---------RSRQRERERREHGVYASSKEEKDWKK-EKSRDRDYDRKRD-RDERDRSRHS 179
S QR++ H K D ++ +S DR ++R+ D R +RDR +
Sbjct: 371 ASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREK-D 429
Query: 180 SRSERDGGSERSSRRN--EPESPRH-RPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPT 236
SR ER+ ++SS R+ + PR R + A +R E DS R + T
Sbjct: 430 SREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDT 489
Query: 237 PSYRDSERSHRLSTRD----RDRSVRGKYSDDTPLPTPSYKY---------------NEW 277
RD S STRD RDR R + + P S Y NE
Sbjct: 490 KESRDPRDSR--STRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNES 547
Query: 278 ADDRRHLGSTPRLSRGRGRREE-------GEEGISFDTEEERQQWEDDQRQADRDWYMMD 330
++ R R+ R RGR E G G D+ + D R Y
Sbjct: 548 RNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWE--TRSSYPER 605
Query: 331 EGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINEDNERWETNRMLTSGVVHR 390
+ Y E N R+Q ++R + R+ N + ++ ++ + G
Sbjct: 606 DRYPERDN------------RDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDE 653
Query: 391 LEVDEDFEEDNAAKV 405
LE DE EE +V
Sbjct: 654 LERDERREERRVDRV 668
Score = 57.0 bits (136), Expect = 1e-07
Identities = 73/289 (25%), Positives = 112/289 (38%), Gaps = 42/289 (14%)
Query: 60 REREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPS 119
RE+ + + ++KS++ K E S+ D R+D S+R +P
Sbjct: 1235 REKTKSLEITGERKSRIDQLKRGEPSRSTSSD-------------RQDSRSHSSRRSSPE 1281
Query: 120 HPGGV---SEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRD-ERDR 175
V S F R R +ER+R EH E++ ++ +R R++DR D+D R+R
Sbjct: 1282 SDRQVHSRSGSFDSRDRLQERDRYEH------DRERERERRDTRQREWDRDADKDWPRNR 1335
Query: 176 SRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSP 235
R R ER+ ER RR+ D+ R + D + S SQ ES
Sbjct: 1336 DRDRLR-ERERERERDKRRDLDRERERLISDSVERDRD--RDRDRTFES---SQIESVKR 1389
Query: 236 TPSYRDSERSHRLSTRDRDRSVRGKYSDDTPL----------PTPSYKYNEWADDRRHLG 285
+ + E L + RD K D L + + E DD L
Sbjct: 1390 CEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLD 1449
Query: 286 STPRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYD 334
L G G EG E IS D +E + ++R+ +D M + D
Sbjct: 1450 DAHSLGSGAG---EGYEPISDDELDEILAGDAEKREDQQDEEKMPDPLD 1495
Score = 54.3 bits (129), Expect = 7e-07
Identities = 100/444 (22%), Positives = 152/444 (34%), Gaps = 60/444 (13%)
Query: 71 KKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWE 130
K + SS K SK D+K + Q K + TPS P + E+
Sbjct: 217 KSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIAL 276
Query: 131 RSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDR-------------SR 177
+ +E+ + + + +++ KD R RD++R+R++ ++ R SR
Sbjct: 277 GKKYKEKYKVKDRIEEKTRDGKD------RGRDFERQREKRDKPRSTSPAGQHHSPISSR 330
Query: 178 HSSRSERDGGS----ERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESP 233
H S S + G S S RR SP ++ RS S +R Q
Sbjct: 331 HHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPR 390
Query: 234 SPTPSYRDSERSHRLSTRDRDR------SVRGK------------YSDDTPLPTPSYKYN 275
+P H +++ DR RGK Y D
Sbjct: 391 HRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDR 450
Query: 276 EWAD--DRRHLGST---PRLSRGRGRREEGE-EGISFDTEEERQQWEDDQRQADRDWYMM 329
E D DRR T L R R+ E S DT+E R D + D Y
Sbjct: 451 EPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDP-RDSRSTRDAHDYRD 509
Query: 330 DEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINEDNERWETNRMLTSGVVH 389
EG D Y E R HL +++ R + NE +RM S
Sbjct: 510 REGRDTHRKEDTYPEESRSYGR-NHL-REESSRTEIRNESRNESRSEIRNDRMGRS---- 563
Query: 390 RLEVDEDFEEDNAAKVHLMV--HNLVPPFLDGRIVFTKQPE----PVIPVKDATSDLAII 443
R V E E+ + + H+ + D + PE P +D D +
Sbjct: 564 RGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFE 623
Query: 444 ARKGSQTVRKHREQKERKKAQHKH 467
R G + R +RE+ +R + +H
Sbjct: 624 RRHGERDRRDNRERDQRPSSPIRH 647
Score = 44.7 bits (104), Expect = 6e-04
Identities = 73/299 (24%), Positives = 120/299 (40%), Gaps = 60/299 (20%)
Query: 84 ESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHG 143
E +K +++ G N R +R + S R+ +PS+ RS ++ R+
Sbjct: 1176 EDAQHRKPMDQKRSSSLGSN-RSNRSHTSGRLRSPSNDSA------HRSGD-DQSGRKRV 1227
Query: 144 VYASSKEEKDWKKEKSRDRDYDRKR--DRDERDRSRHSSRSERDGGSERSSRRNEPESPR 201
+++ S+ D +K KS + +RK D+ +R S+ S+R SSRR+ PES R
Sbjct: 1228 LHSGSR---DREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR 1284
Query: 202 H-RPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGK 260
+ + SR +E D ++E R+ ER R TR R+
Sbjct: 1285 QVHSRSGSFDSRDRLQERD---------RYEHD------RERERERR-DTRQRE------ 1322
Query: 261 YSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQWEDDQR 320
+ D P + DR L R R R E ++ D E ER + +R
Sbjct: 1323 WDRDADKDWPRNR------DRDRL-------RERERERERDKRRDLDRERERLISDSVER 1369
Query: 321 QADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRI-SAQRRQINEDNERWE 378
DRD D ++ S + V+R E L + ++ + S R + D ER +
Sbjct: 1370 DRDRD---RDRTFES-------SQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMD 1418
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 73.9 bits (180), Expect = 9e-13
Identities = 63/243 (25%), Positives = 107/243 (44%), Gaps = 29/243 (11%)
Query: 28 KSKSAASEQHVFKAPAPRPSLLGLDLLASLKRREREEKDDGEDKKKSKVSSYKDWEESKD 87
+S+S ++ K+P + S + + R+++ D +K K K K+ + K+
Sbjct: 340 RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEK-ERVKEKDREKE 398
Query: 88 DQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYAS 147
+++ E E + G+N +D+ R E+ E+ R+RERE+ EH
Sbjct: 399 REREKEREKEKERGKNKDRDKEREKDR-----------EKDKEKDREREREK-EHEKDRD 446
Query: 148 SKEEKDWKKEKSRDRD----YDRKRDRDERDRS--RHSSRSERDGGSERSSRRNEPESPR 201
++EK+ KEK R++D D KR +D++ R+ R + S R S R RR S
Sbjct: 447 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 506
Query: 202 HRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKY 261
P+ + T R SSR S + R+ ER H R+R+RS +
Sbjct: 507 RSPRTSKTIKRK----------SSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK 556
Query: 262 SDD 264
S +
Sbjct: 557 SSN 559
Score = 58.2 bits (139), Expect = 5e-08
Identities = 59/252 (23%), Positives = 105/252 (41%), Gaps = 24/252 (9%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
+ +ERE + + E +K+ + +D E KD +KD E++ + + KDR
Sbjct: 395 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRD-------- 446
Query: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSR 177
E+ E+ +++ERE+ + K +KD KK ++ R Y+ R R R
Sbjct: 447 -------KEKEKEQDKEKEREK-DRSKEIDEKRKKD-KKSRTPPRSYNASRRSRSSSRER 497
Query: 178 HSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTP 237
RS S R+S+ + +S R P + + E++ + S RR + S S
Sbjct: 498 RRRRSRSSSRSPRTSKTIKRKSSR-SPSPRSRNKKDKKREKERDHISERRERERSTSMRK 556
Query: 238 SYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRR 297
S D + +L S++ K + P + S + DD+ + + G
Sbjct: 557 SSNDRDGKEKL--EKNSTSLKEKEHNKEPDSSVSKE----VDDKDAPRTEENKIQHNGNC 610
Query: 298 EEGEEGISFDTE 309
+ EE +S TE
Sbjct: 611 QLNEENLSTKTE 622
Score = 53.5 bits (127), Expect = 1e-06
Identities = 69/304 (22%), Positives = 117/304 (38%), Gaps = 34/304 (11%)
Query: 34 SEQHVFKAPAPRPSLLGLDLLASLKR-RERE-------EKDDGE-DKKKSKVSSYKDWEE 84
S + K P P +L +KR RE + E + G+ +++K S +
Sbjct: 256 SNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK 315
Query: 85 SKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGV 144
S+ K Q+ R RS + + + R R++ R R
Sbjct: 316 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD 375
Query: 145 YASSKEEKDWKKEKSRDRDYDRKRDRD-------------ERDRSRHSSRSERDGGSERS 191
EK +KE+ +++D +++R+R+ +RD+ R R +
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 435
Query: 192 SRRNEPESPRHRPKDAATPSRSTWEEEDS-GYGSSRRSQWESPSPTPSYRDSERSHRLST 250
R E E R + K+ E++ S R+ +S +P SY S RS R S+
Sbjct: 436 EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS-RSSS 494
Query: 251 RDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGR--GRREEGEEGISFDT 308
R+R R R + S +P + + K R+ S SR + +RE+ + IS
Sbjct: 495 RERRRR-RSRSSSRSPRTSKTIK-------RKSSRSPSPRSRNKKDKKREKERDHISERR 546
Query: 309 EEER 312
E ER
Sbjct: 547 ERER 550
Score = 48.1 bits (113), Expect = 5e-05
Identities = 59/275 (21%), Positives = 110/275 (40%), Gaps = 47/275 (17%)
Query: 98 DQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKE 157
++ + +R+ + + SA +E S G +E RSR R + + S+ ++ K
Sbjct: 276 EEVMKRVREAQSFISAAIEPES--GKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKH 333
Query: 158 KSRDRDYDRKRDRDER-DRSRHSSRS---ERDGGSERSSRRNEPESPRHRPKDAATPSRS 213
+SR + R R +D R +S H RS ER RS R++ + R + K+ +
Sbjct: 334 RSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE-----KE 388
Query: 214 TWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYK 273
+E+D R+ ER R R++++ RGK D
Sbjct: 389 RVKEKD--------------------REKERE-REKEREKEKE-RGKNKD---------- 416
Query: 274 YNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGY 333
D R + R R E E D E+E++Q ++ +R+ DR + ++
Sbjct: 417 ----RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 472
Query: 334 DEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRR 368
+ + S + RR +++++R + R
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 507
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 73.9 bits (180), Expect = 9e-13
Identities = 63/243 (25%), Positives = 107/243 (44%), Gaps = 29/243 (11%)
Query: 28 KSKSAASEQHVFKAPAPRPSLLGLDLLASLKRREREEKDDGEDKKKSKVSSYKDWEESKD 87
+S+S ++ K+P + S + + R+++ D +K K K K+ + K+
Sbjct: 224 RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEK-ERVKEKDREKE 282
Query: 88 DQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYAS 147
+++ E E + G+N +D+ R E+ E+ R+RERE+ EH
Sbjct: 283 REREKEREKEKERGKNKDRDKEREKDR-----------EKDKEKDREREREK-EHEKDRD 330
Query: 148 SKEEKDWKKEKSRDRD----YDRKRDRDERDRS--RHSSRSERDGGSERSSRRNEPESPR 201
++EK+ KEK R++D D KR +D++ R+ R + S R S R RR S
Sbjct: 331 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 390
Query: 202 HRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKY 261
P+ + T R SSR S + R+ ER H R+R+RS +
Sbjct: 391 RSPRTSKTIKRK----------SSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK 440
Query: 262 SDD 264
S +
Sbjct: 441 SSN 443
Score = 58.2 bits (139), Expect = 5e-08
Identities = 59/252 (23%), Positives = 105/252 (41%), Gaps = 24/252 (9%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
+ +ERE + + E +K+ + +D E KD +KD E++ + + KDR
Sbjct: 279 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRD-------- 330
Query: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSR 177
E+ E+ +++ERE+ + K +KD KK ++ R Y+ R R R
Sbjct: 331 -------KEKEKEQDKEKEREK-DRSKEIDEKRKKD-KKSRTPPRSYNASRRSRSSSRER 381
Query: 178 HSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTP 237
RS S R+S+ + +S R P + + E++ + S RR + S S
Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSR-SPSPRSRNKKDKKREKERDHISERRERERSTSMRK 440
Query: 238 SYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRR 297
S D + +L S++ K + P + S + DD+ + + G
Sbjct: 441 SSNDRDGKEKL--EKNSTSLKEKEHNKEPDSSVSKE----VDDKDAPRTEENKIQHNGNC 494
Query: 298 EEGEEGISFDTE 309
+ EE +S TE
Sbjct: 495 QLNEENLSTKTE 506
Score = 53.5 bits (127), Expect = 1e-06
Identities = 69/304 (22%), Positives = 117/304 (38%), Gaps = 34/304 (11%)
Query: 34 SEQHVFKAPAPRPSLLGLDLLASLKR-RERE-------EKDDGE-DKKKSKVSSYKDWEE 84
S + K P P +L +KR RE + E + G+ +++K S +
Sbjct: 140 SNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK 199
Query: 85 SKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGV 144
S+ K Q+ R RS + + + R R++ R R
Sbjct: 200 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD 259
Query: 145 YASSKEEKDWKKEKSRDRDYDRKRDRD-------------ERDRSRHSSRSERDGGSERS 191
EK +KE+ +++D +++R+R+ +RD+ R R +
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 319
Query: 192 SRRNEPESPRHRPKDAATPSRSTWEEEDS-GYGSSRRSQWESPSPTPSYRDSERSHRLST 250
R E E R + K+ E++ S R+ +S +P SY S RS R S+
Sbjct: 320 EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS-RSSS 378
Query: 251 RDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGR--GRREEGEEGISFDT 308
R+R R R + S +P + + K R+ S SR + +RE+ + IS
Sbjct: 379 RERRRR-RSRSSSRSPRTSKTIK-------RKSSRSPSPRSRNKKDKKREKERDHISERR 430
Query: 309 EEER 312
E ER
Sbjct: 431 ERER 434
Score = 48.1 bits (113), Expect = 5e-05
Identities = 59/275 (21%), Positives = 110/275 (40%), Gaps = 47/275 (17%)
Query: 98 DQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKE 157
++ + +R+ + + SA +E S G +E RSR R + + S+ ++ K
Sbjct: 160 EEVMKRVREAQSFISAAIEPES--GKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKH 217
Query: 158 KSRDRDYDRKRDRDER-DRSRHSSRS---ERDGGSERSSRRNEPESPRHRPKDAATPSRS 213
+SR + R R +D R +S H RS ER RS R++ + R + K+ +
Sbjct: 218 RSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE-----KE 272
Query: 214 TWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYK 273
+E+D R+ ER R R++++ RGK D
Sbjct: 273 RVKEKD--------------------REKERE-REKEREKEKE-RGKNKD---------- 300
Query: 274 YNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGY 333
D R + R R E E D E+E++Q ++ +R+ DR + ++
Sbjct: 301 ----RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 356
Query: 334 DEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRR 368
+ + S + RR +++++R + R
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 391
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 69.3 bits (168), Expect = 2e-11
Identities = 58/219 (26%), Positives = 101/219 (46%), Gaps = 26/219 (11%)
Query: 58 KRREREEK-----DDGEDKKKSKVSS-YKDWEESKD---DQKDAEEEGGDQAGQNIRKDR 108
K RE+E + D G ++++S+ ++ S+D D++D + E + + R+DR
Sbjct: 309 KEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDR 368
Query: 109 HYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKR 168
Y R G E+ ERSR+R +E+R G K ++D + RD D K+
Sbjct: 369 DYDKER-------GNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKK 421
Query: 169 D-RDERDRSR---HSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGS 224
+ + R RSR H SRS +RS R++ +S +H+ + ++ S GS
Sbjct: 422 EKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR------SRSGS 475
Query: 225 SRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSD 263
R+ S + S+ R +R ++RS + +SD
Sbjct: 476 QGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSD 514
Score = 59.3 bits (142), Expect = 2e-08
Identities = 67/292 (22%), Positives = 114/292 (39%), Gaps = 46/292 (15%)
Query: 94 EEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKD 153
+EG ++ +++ + R R +P RSR R R HG SS +++
Sbjct: 245 KEGAEEIDRHVERRRSRSPRRSLSPRRSP-------RRSRSRSHHREGHG---SSSFDRE 294
Query: 154 WKKEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRS 213
++EK R R +R+ ER++ R SRS G R SR E R R +D R
Sbjct: 295 LEREKERQR---LEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRD 351
Query: 214 TWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYK 273
E + RR + + R+ ER R R +++ RG+ + K
Sbjct: 352 RDREREKENERGRRRDRDYDKERGNEREKER-ERSRERSKEQRSRGEVEEK--------K 402
Query: 274 YNEWADDRRHLG---------------STPRLSRGRGR-REEGEEGISFDTEEERQQWED 317
+ E DDRRH S R R R R R G+ S E+ + +
Sbjct: 403 HKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNE 462
Query: 318 DQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQ 369
+ ++++ +G + S + ++RE K+K ++ S + +
Sbjct: 463 SKEKSNKRSRSGSQGRTD--------SVEKSKKREHSPSKEKSRKRSRSKER 506
Score = 48.9 bits (115), Expect = 3e-05
Identities = 42/171 (24%), Positives = 68/171 (39%), Gaps = 29/171 (16%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
K RER + E + + +V K +E KDD++ +++ + ++ +H RS E
Sbjct: 380 KERERSRERSKEQRSRGEVEEKKH-KEDKDDRRHRDDKRDSK-----KEKKHSRSRSRER 433
Query: 118 PSHPGGVSEEFWERSRQRERER----------------------REHGVYASSKEEKDWK 155
S +RSR R +E+ R V S K E
Sbjct: 434 KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPS 493
Query: 156 KEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKD 206
KEKSR R ++R +RD S +S++ S E + +H+ KD
Sbjct: 494 KEKSRKRSRSKERSH-KRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
Score = 45.1 bits (105), Expect = 4e-04
Identities = 32/160 (20%), Positives = 70/160 (43%), Gaps = 22/160 (13%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRS----- 112
+ R +E++ GE ++K K KD +DD++D+++E ++ + RS
Sbjct: 386 RERSKEQRSRGEVEEK-KHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNA 444
Query: 113 -------ARVETPSHPGGVSEEFWERSRQ---------RERERREHGVYASSKEEKDWKK 156
++ ++ H E+ +RSR + ++REH ++ K
Sbjct: 445 GKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSK 504
Query: 157 EKSRDRDYDRKRDRDERDRSRHSSRSERDGGSERSSRRNE 196
E+S RD+ +D+ ++ R S E++ ++ ++E
Sbjct: 505 ERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
Score = 34.7 bits (78), Expect = 0.57
Identities = 50/223 (22%), Positives = 79/223 (35%), Gaps = 20/223 (8%)
Query: 156 KEKSRDRDYDRKRDRDERDR--SRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRS 213
K + R D K +E DR R SRS R S R S P R R S
Sbjct: 234 KTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRS----PRRSRSRSHHREGHGSS 289
Query: 214 TWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYK 273
+++ E +R + E+ ++ E+ R S R DR + + S +
Sbjct: 290 SFDRELEREKERQRLEREA-------KEREKERRRS-RSIDRGLERRRSRSRERHRSRSR 341
Query: 274 YNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGY 333
+ DRR RGRR + D ++ER + +R+ R+
Sbjct: 342 SRDRKGDRRDRDREREKENERGRRRDR------DYDKERGNEREKERERSRERSKEQRSR 395
Query: 334 DEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINEDNER 376
E +D R R+ +K+K+ S R + + R
Sbjct: 396 GEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSR 438
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 66.6 bits (161), Expect = 1e-10
Identities = 69/236 (29%), Positives = 104/236 (44%), Gaps = 17/236 (7%)
Query: 112 SARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRD 171
+A + +PS S + E + +R RE + A ++K+ K+ SR R R+R
Sbjct: 202 AAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTP 261
Query: 172 ERDRSRHS-SRSERDGGSERSSRRNEPESPRHR---PKDAATPSRSTWEEEDSGYGSSRR 227
R R S SRS R S+ SRR +SPR R ++ SRST + D +
Sbjct: 262 SSSRHRRSRSRSRRRSHSKSRSRRRS-KSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK 320
Query: 228 SQWESPSPTPSYRDSERSHRLS-TRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGS 286
+ S +P SY + RS S R R RS G S P +P K + RRH
Sbjct: 321 KR--SKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKP-RSPKRKLSRSPSPRRHKKE 377
Query: 287 TPR-----LSRGRGRREEGEEGISFDTEEERQ---QWEDDQRQADRDWYMMDEGYD 334
+ SR R ++ S D E++R+ + + D +Q RD+ ++GYD
Sbjct: 378 KKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYD 433
Score = 49.3 bits (116), Expect = 2e-05
Identities = 58/276 (21%), Positives = 108/276 (39%), Gaps = 22/276 (7%)
Query: 48 LLGLDLLASLKRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKD 107
L+ L + +E EE + +S +S+ + ++ ++ ++ + + +
Sbjct: 205 LVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSS 264
Query: 108 RHYRS-ARVETPSHPGGVSEEFWERSRQRERERREHGVYASS--------KEEKDWKKEK 158
RH RS +R SH S + R+R RE G + S KE+K+ K+ K
Sbjct: 265 RHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSK 324
Query: 159 SRDRDYDR-KRDRD-----ERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSR 212
+ + Y +R R R RSR +RS + S + P RH+ + +
Sbjct: 325 TPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDK 384
Query: 213 STWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRG------KYSDDTP 266
+E S ++ + +S++ + TRD D +G K + P
Sbjct: 385 ERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKP 444
Query: 267 LPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEE 302
+ T S K E + + + G + R S+ G E+
Sbjct: 445 IETGSPKTKECSVE-KGTGDSLRESKVNGDDHHEED 479
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 65.5 bits (158), Expect = 3e-10
Identities = 98/485 (20%), Positives = 194/485 (40%), Gaps = 41/485 (8%)
Query: 54 LASLKRREREEKDDGEDKKKSKV---SSYKDWEE-----SKDDQKDAEEEGGDQAGQNIR 105
L L+R+ REEK +++ +V K+W + K+++K EEE Q
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274
Query: 106 KDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYD 165
+++ + R E + E E +Q++R RRE + +EE+ ++E+ R++
Sbjct: 275 EEQLRKLERQE-------LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Query: 166 RKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSS 225
R++ + R++ + ER E+ RR + E R + R EEE
Sbjct: 328 REQQEERREQQLRREQEER---REQQLRREQEEERREQ------QLRREQEEERREQQLR 378
Query: 226 RRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLG 285
R Q + R +L R++ + + L E ++R
Sbjct: 379 REQQLRREQQLRREQQLRREQQL-RREQQLRREQQLRREQQLRREQQLRREQEEERHEQK 437
Query: 286 STPRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSE 345
R +RE+ E EEE ++ E ++R+ +E + +
Sbjct: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Query: 346 DYVRRREQHLHKQKQKRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKV 405
+ RREQ L +++++R QR + E+ ER + + L S R E +E E+
Sbjct: 498 EQQERREQQLRREQEER-REQRLKRQEEEERLQ--QRLRSEQQLRREQEERREQ------ 548
Query: 406 HLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQH 465
L+ + R+ ++ + + ++ D + + + R REQ+ER + +
Sbjct: 549 ------LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602
Query: 466 KHWELAGTKLGDIMGVK-KEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKS 524
K E+ + + + K EEP++ + E++ ++R+ + E K+
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 525 ILEQR 529
E+R
Sbjct: 663 EEEER 667
Score = 65.5 bits (158), Expect = 3e-10
Identities = 95/511 (18%), Positives = 194/511 (37%), Gaps = 41/511 (8%)
Query: 54 LASLKRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSA 113
L S ++ RE+++ E K + + E + K +EE DQ + + R R
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 114 RVETPSHPGGVSEEFWERSRQRER------------ERREHGVYASSKEEK---DWKKEK 158
R + + E ER Q ER ERR+ + + +EE+ ++E+
Sbjct: 592 REQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651
Query: 159 SRDRDYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEE 218
R+ KR+ +E + R + E+ E E R R K + E E
Sbjct: 652 QERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESE 711
Query: 219 DSG-----YGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLP-TPSY 272
Y R+ + + + R L ++ +R+ R + ++ T +
Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQW 771
Query: 273 KYNEWAD-DRRHLGSTPRLSRGRGRREEGEEGIS-----FDTEEERQQWEDDQRQADRDW 326
+ E ++ R+ L + P L R R+ EE EEE++Q +R+ +++
Sbjct: 772 QAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL 831
Query: 327 YMMDEGYDEFHNPLA---YSSEDYVRRREQHLHKQKQKRISAQRRQINEDNERWETNRML 383
++E A ED ++ ++ Q+Q+R R Q+ E+ +R
Sbjct: 832 QFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYA 891
Query: 384 TSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAII 443
+ +L ++ ++ ++ R +Q ++ L
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREERE-----KRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 444 ARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMGVKKEEEPDKAVTEDGKVDYRTEQ 503
R+ + + R+ ++ KK Q K +L LG+ ++ +E +K E+ ++ EQ
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQL----LGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
Query: 504 KFAD--HMKRKSEASSEFAKKKSILEQRQYL 532
+ +R+ E ++ KK + ++ + L
Sbjct: 1003 LLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
Score = 63.5 bits (153), Expect = 1e-09
Identities = 97/530 (18%), Positives = 216/530 (40%), Gaps = 46/530 (8%)
Query: 58 KRRER----EEKDDGEDKKKSKVSSYKDWEESKDDQ--KDAEEEGGDQ---AGQNIRKDR 108
+RRER EE++ E +++ + ++ EE ++ + + EEE Q + Q +R+++
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 109 HYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKR 168
R ++ + +E E+ +RE+E R + +E + + ++ ++ +++
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602
Query: 169 DRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRS 228
R+E +R R E+ E + + ++ + E+++ +R
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 229 QWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRR-HLGST 287
+ E R+ E R + + + + +P ++ AD R+ + S
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722
Query: 288 PRLSRGRGRREEGEE-------GISFDTEE--ERQQWEDDQRQADRDWYMMDEGYDE--- 335
PR G+ RR+E EE + + EE RQQ E++QR+ D W E E
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR-DFTWQWQAEEKSERGR 781
Query: 336 ----FHNPLAYSSEDYVRRREQHLHKQK---QKRISAQRRQINEDNER-----WETNRML 383
PL E +R E+ +Q+ ++ QRR+ + E+ E ++
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 384 TSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAII 443
+L+ +ED +++ + + K+ + K A +
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ--- 898
Query: 444 ARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMGVKKEEEP------DKAVTEDGKV 497
RK Q +++ E+ +R++ + + + + + +++EEE +K ++ +
Sbjct: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER 958
Query: 498 DYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRD 547
YR ++K K + E K++ +++Y +QQE ++R+
Sbjct: 959 QYRKDKKL--QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Score = 63.2 bits (152), Expect = 2e-09
Identities = 80/396 (20%), Positives = 158/396 (39%), Gaps = 55/396 (13%)
Query: 57 LKRREREEKDDGEDKKKSKVSSYKDWEESKD-----DQKDAEEEGGDQAGQNIRKDRHYR 111
L+R++ EE+ + +++++ + + EE ++ +Q++ E+ + + R+++ R
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 112 SARVETPSHPGGVSEEFWERSRQRERE---RREHGVYASS--------KEEKDWKKEKSR 160
+ E E+ R +Q RE RRE + + E+ ++E+
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 425
Query: 161 DRDYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHR--------PKDAATPSR 212
R+ + +R + ++ R R +R+ R + E E+ RH +D R
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR 485
Query: 213 STW---EEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPT 269
W EEE+ RR Q ++ R RL ++ + ++ + + L
Sbjct: 486 ERWLKLEEEERREQQERREQ-----QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Query: 270 PSYKYNEW---ADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQQ---WEDDQR--- 320
+ E ++ + L R R + +EE + + EE RQQ E ++R
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 321 ------------QADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRR 368
+ R+ + E +E SE+ RR+Q L +++Q+R QR
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER-REQRL 659
Query: 369 QINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAK 404
+ E+ ER E R+ R E + EE A+
Sbjct: 660 KREEEEERLE-QRLKREHEEERREQELAEEEQEQAR 694
Score = 59.7 bits (143), Expect = 2e-08
Identities = 72/333 (21%), Positives = 134/333 (40%), Gaps = 31/333 (9%)
Query: 57 LKRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQN----IRKDRHYRS 112
L R+ER+ K E++K + + + E D+Q+ +EG Q Q R+D
Sbjct: 1572 LSRQERDRKFRLEEQKVRRQEQERKFME--DEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 113 ARVETPSHPGGVSEEFWERSRQRERERRE----HGVYASSKEEKDWKKEKSRDRDYDRKR 168
R E H +F E Q R+ RE H +EE+ +E + ++R
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Query: 169 DRDERDRSRHSSRSERDGG---SERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSS 225
DR R+ + R ER+ E+ RR E E + R E+E
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL----RQETEQEQL----R 1741
Query: 226 RRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLG 285
R+ ++ R +L ++RDR R + + + DR+
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRKFREE--EQLRQEREEQQLRSQESDRKFR- 1798
Query: 286 STPRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYD-EFHNPLAYSS 344
+ R+E E+ + + + +WE++Q Q + + + D ++ +++
Sbjct: 1799 -----EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT 1853
Query: 345 EDYVRRREQHL-HKQKQKRISAQRRQINEDNER 376
++ RR EQ L +++QKR + R++ E++ R
Sbjct: 1854 QEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
Score = 57.0 bits (136), Expect = 1e-07
Identities = 97/560 (17%), Positives = 206/560 (36%), Gaps = 105/560 (18%)
Query: 61 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDA------EEEGGDQAGQNIRKDRHYRSAR 114
E EEK+ +++ + + EE + Q+ EEE G Q Q R+ + R
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR-- 870
Query: 115 VETPSHPGGVSEEFWERSRQRERERREHGVYAS---------------------SKEEKD 153
++ W + ER+RR H +YA +EE++
Sbjct: 871 -----------DQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Query: 154 WKKEKSRDRDYDRKRD---------RDERDRSRHSSRSERDGGSERSSRR------NEPE 198
++ + ++R Y + R+ER++ R R + ++ ++ EPE
Sbjct: 920 KRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979
Query: 199 SPRHRPKDAATPSRSTWEEEDSGY-----GSSRRSQWE---------SPSPTPSYRDSER 244
R + ++ ++E+ RR +WE R+
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 245 SHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGI 304
RL R+R +Y ++ L + + R R R ++ EE +
Sbjct: 1040 KRRLQERER------QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 305 SFD-------TEEERQQWEDDQRQADRDWYMMDEGYDEFHNPL--AYSSEDYVRRREQHL 355
+ E ERQ E+++ Q + + + +E L Y E+ V++ E+ L
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Query: 356 ---HKQKQKRISAQRRQINEDNERWETNRML-TSGVVHRLEVDEDFEEDNAAKVHLMVHN 411
+K++R +R+ E+ + E ++L R E + + E+ +
Sbjct: 1154 LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Query: 412 LVPPFLDGRIVFTKQPEPVIPVKD--------------ATSDLAIIARKGSQTVRK-HRE 456
+ + +PE V+D D + R+ Q ++ E
Sbjct: 1214 YRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGE 1273
Query: 457 QKERKKAQ-HKHWELAGTKLGDIMGVKKEEEPD-KAVTEDGKVDYRTEQKFADHMKRKSE 514
Q+ER + Q + W+ + +++EE+ + K + + + ++ + +R+ E
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
Query: 515 ASSEFAKKKSILEQRQYLPI 534
+F +++ +L++R+ P+
Sbjct: 1334 TDRKFREEEQLLQEREEQPL 1353
Score = 57.0 bits (136), Expect = 1e-07
Identities = 107/542 (19%), Positives = 205/542 (37%), Gaps = 75/542 (13%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKD----------WEESKDDQ--------KDAEEEGGDQ 99
+ RER+ +++ E +++ + Y+D WE K++ K E E Q
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 100 AGQNIRKDRHYRSARVETPSHPGGVSEEF---WERSRQRERERREHGVYASSKEEKDWKK 156
+ +DR + + H G +E ER R ++R+R H E ++ K+
Sbjct: 1253 LEDSQLRDRQSQ----QDLQHLLGEQQERDREQERRRWQQRDR--HFPEEEQLEREEQKE 1306
Query: 157 EKSRDRDYDRKRD--RDERDRSRHSSRSERDGGSERSSRRNEPESP-RHRPKDA------ 207
K RDR ++ R+ER+ R ++R E + E P R + +D
Sbjct: 1307 AKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Query: 208 ---ATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVR------ 258
R EEE R ++ R ER +L +DRDR R
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEE--QQLRCQEREQQL-RQDRDRKFREEEQQL 1423
Query: 259 GKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEER-QQWED 317
+ D + +R+ L +L + R R+ EE + + EE++ + E
Sbjct: 1424 SRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQER 1483
Query: 318 DQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRR---REQHLHKQKQKRISAQRRQINEDN 374
D++ + + + + D S++ R+ EQ LH+Q+++R Q Q
Sbjct: 1484 DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543
Query: 375 ERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQP--EPVIP 432
ER G R + D F E+ + L D + +Q
Sbjct: 1544 ER---------GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 433 VKDATSDLAIIARKGSQTVRKHREQK--------ERKKAQHKHWELAGTKLGDIMGVKKE 484
K + + ++G Q +R+ R++K + ++ Q H + K + +
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654
Query: 485 EEPDKAVTEDGKVDYRTE----QKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE 540
+E ++ + D +R E Q+ + R+ E +F +++ L +++ F +++
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ 1714
Query: 541 LL 542
L
Sbjct: 1715 QL 1716
Score = 53.1 bits (126), Expect = 2e-06
Identities = 90/482 (18%), Positives = 187/482 (38%), Gaps = 56/482 (11%)
Query: 59 RREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGD-QAGQNIRKDRHYR------ 111
R++R+ K E+++ S+ + + E + + E E + Q +R++RH +
Sbjct: 1409 RQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQ 1468
Query: 112 --SARVETPSHPGGVSEEFWE-----RSRQRERERREHGVYASSKEEKDWKKEKSRDRDY 164
R E H +F E R ++R+R+ RE + + E K ++E+ R
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ 1528
Query: 165 DRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGS 224
+++ E + R R G +R R+ + + + + +E D +
Sbjct: 1529 RQRKFLQEEQQLRRQER-----GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL 1583
Query: 225 SRRSQWESPSPTPSYRDSERSHRLSTRDRDRSVRG-KYSDDTPL--PTPSYKYNEWADDR 281
+ D ++ R + + R R K+ +D L + + DR
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR 1643
Query: 282 RHLGSTPRLSRGRGRREEGEEGISFDT-----EEERQQWEDDQRQADRDWYMMDEGYDEF 336
+ L P+L RR+E E+ + D EEE+ E +++Q R D + E
Sbjct: 1644 KFLEEEPQL-----RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ--ERDRKFREE 1696
Query: 337 HNPLAYSS-EDYVRRREQHLHKQKQKRISAQRRQINEDNERWETNRMLTSGVVHRLEVDE 395
L E + EQ L +Q+ +R + Q+ ++ E+ + R +R ++E
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER----YRKILEE 1752
Query: 396 DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHR 455
+ + L F + + ++ E + +++ + + +R+ R
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF-----REEEQLRQER 1807
Query: 456 EQKERKKAQHK---HWELAGTKLGDIMGVKKEEEPDKAVTEDGKVDYRTEQKFADHMKRK 512
E+++ + Q WE +L EE ++ + ++ YR E++FA K +
Sbjct: 1808 EEQQLRPQQRDGKYRWEEEQLQL---------EEQEQRLRQERDRQYRAEEQFATQEKSR 1858
Query: 513 SE 514
E
Sbjct: 1859 RE 1860
Score = 52.4 bits (124), Expect = 3e-06
Identities = 105/535 (19%), Positives = 200/535 (37%), Gaps = 89/535 (16%)
Query: 58 KRREREEKDDGED---KKKSKVSSYKDWEES--KDDQKDAEEEGGDQAGQNIRKDRHYRS 112
K RE EE E+ +++ + ++WE K D+ EEE Q +R++R R
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE------QLLREEREKR- 1041
Query: 113 ARVETPSHPGGVSEEFWERSRQ-----RERERREHGVYASSKEEKDWKKEKSRDRDYDRK 167
R++ EE + Q RE RR+ KEE+ ++E+ R+ K
Sbjct: 1042 -RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEK 1100
Query: 168 RDRDERDR-----SRHSSRSERDGGSERSSRRNEPESPRHRPKDAA----------TPSR 212
R R ER+R E+ ER RR + ++R ++ P +
Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160
Query: 213 STWEEEDSGYGSSRRSQWES-----PSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPL 267
+E + Y Q E ++ ER +R + + + +Y D+
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Query: 268 PTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEEERQ-----------QWE 316
+ +W ++ + ++ +GR E + +RQ Q E
Sbjct: 1221 SDLKW---QWEPEKENAVRDNKV-YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 317 DDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINEDNE- 375
D+ Q R W D + E E+ + R EQ K++ ++ +++ + E+ E
Sbjct: 1277 RDREQERRRWQQRDRHFPE---------EEQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327
Query: 376 ---RWETNRML----------TSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGRIV 422
R ET+R + R E D F E+ L FL+
Sbjct: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE-----ELRHQEQGRKFLEEEQR 1382
Query: 423 FTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKL-GDIMGV 481
+Q +K+ + + ++ Q +R+ R++K R++ Q + K + V
Sbjct: 1383 LRRQERERKFLKE---EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV 1439
Query: 482 KKEEEPDKAVTEDGKVDYRTEQKFADH----MKRKSEASSEFAKKKSILEQRQYL 532
+++E K + E+ ++ +KF + +R+ + + + LE+ Q L
Sbjct: 1440 RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
Score = 48.1 bits (113), Expect = 5e-05
Identities = 62/299 (20%), Positives = 112/299 (37%), Gaps = 31/299 (10%)
Query: 87 DDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYA 146
D++K A +G + Q+ R++ R R E + EE +R RQ+ +E+
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQR--RFEPRDRQ--LEEEPGQRRRQKRQEQERE---L 148
Query: 147 SSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSSRSER----------------DGGSER 190
+ EE+ K+E+ RD R+ + R R R ER + E
Sbjct: 149 AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEE 208
Query: 191 SSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLST 250
RR E R + ++ R E +D + +W R E +
Sbjct: 209 QLRRRELLELRRKGREEKQQQRR--ERQDRVFQEEEEKEWRKRETV--LRKEEEKLQEEE 264
Query: 251 RDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEE 310
R R ++ + L + ++++ RL R + R + EE EE
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQ----QRLRREQQLRRKQEEERREQQEE 320
Query: 311 ERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQ 369
R+Q E ++Q +R + +E ++ RR +Q +Q+++R Q R+
Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Score = 45.4 bits (106), Expect = 3e-04
Identities = 48/262 (18%), Positives = 93/262 (35%), Gaps = 19/262 (7%)
Query: 134 QRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSERSSR 193
+R R + + ++E+D ++ + RDR + + + R + + R +G + +
Sbjct: 99 KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQ 158
Query: 194 RNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLSTRDR 253
+ R R + R W+E + + Q T + D E+ R +
Sbjct: 159 ERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLEL 218
Query: 254 DRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGEEGISFDTEE--- 310
R R + E + R + R + + EE + EE
Sbjct: 219 RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 311 ----------ERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVR------RREQH 354
ERQ+ E Q++ R+ + + +E E R RREQ
Sbjct: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338
Query: 355 LHKQKQKRISAQRRQINEDNER 376
L +++++R Q R+ E+ R
Sbjct: 339 LRREQEERREQQLRREQEEERR 360
Score = 45.4 bits (106), Expect = 3e-04
Identities = 46/210 (21%), Positives = 89/210 (42%), Gaps = 19/210 (9%)
Query: 57 LKRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVE 116
L+R+ERE K E+++ + + + E + +++ E+E +R+ YR E
Sbjct: 1700 LRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE-------QLRRQERYRKILEE 1752
Query: 117 TPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKS--RDRDYDRKRDRDERD 174
P EE R ++R+R+ RE +EE+ + ++S + R+ ++ R E
Sbjct: 1753 EQLRPE--REEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 175 RSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPS 234
+ R R + E + E E + +D + EE+ + SRR + E
Sbjct: 1811 QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRA----EEQFATQEKSRREEQELWQ 1866
Query: 235 PTPSYRDSERSHRLSTRDRDRSVRGKYSDD 264
R ER +L R+ +R + ++
Sbjct: 1867 EEEQKRRQERERKL----REEHIRRQQKEE 1892
Score = 36.2 bits (82), Expect = 0.20
Identities = 30/153 (19%), Positives = 69/153 (45%), Gaps = 23/153 (15%)
Query: 62 REEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSHP 121
R E+++ + +++ + +++ EE +++ ++ ++ + R++ R R E P
Sbjct: 1756 RPEREEQQLRRQERDRKFRE-EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRP 1814
Query: 122 GGVSEEF-WERSR----------QRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDR 170
++ WE + ++ER+R+ + +EK ++E+ ++ ++KR R
Sbjct: 1815 QQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKR-R 1873
Query: 171 DERDRSRHSSRSERDGGSERSSRRNEPESPRHR 203
ER+R E RR + E RHR
Sbjct: 1874 QERERKLR----------EEHIRRQQKEEQRHR 1896
Score = 33.9 bits (76), Expect = 0.98
Identities = 63/356 (17%), Positives = 121/356 (33%), Gaps = 76/356 (21%)
Query: 171 DERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQW 230
DE R+R + S RR E + R P+D EE+ G ++ Q
Sbjct: 96 DEEKRARCDGKE-----SLLQDRRQEEDQRRFEPRDRQL-------EEEPGQRRRQKRQE 143
Query: 231 ESPSPTPSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRL 290
+ SE+ RL RDR R
Sbjct: 144 QERELAEGEEQSEKQERLEQRDRQR----------------------------------- 168
Query: 291 SRGRGRREEGEEGISFDTEEERQQWED-DQRQADRDWYMMDEGYDEFHNPLAYSSEDYVR 349
R+E + +RQ+W++ ++R+A+ + +G H + E+ +R
Sbjct: 169 ------RDE-------ELWRQRQEWQEREERRAEEEQLQSCKG----HETEEFPDEEQLR 211
Query: 350 RREQ-------HLHKQKQKRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNA 402
RRE KQ+Q+R R E+ + W + +L+ +E +
Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQREL 271
Query: 403 AKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKGSQTVRK----HREQK 458
+ + L L +Q + + + R+ Q R+ REQ+
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ 331
Query: 459 ERKKAQHKHWELAGTKLGDIMGVKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSE 514
E ++ Q E + + ++EE ++ + + + + R +Q + R+ +
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Score = 32.7 bits (73), Expect = 2.2
Identities = 17/39 (43%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 1156 KSRQENRRRAKEEASAM-EEEMALAEEQLRARRQEQEKR 1193
+ RQE R+ +EE EEE L EE+ + RRQE+E++
Sbjct: 921 RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
Score = 32.3 bits (72), Expect = 2.8
Identities = 17/39 (43%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
Query: 1156 KSRQENRRRAKEEAS-AMEEEMALAEEQLRARRQEQEKR 1193
+ RQE R+ +EE EEE L EE+ + RRQE E++
Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
Score = 32.3 bits (72), Expect = 2.8
Identities = 15/38 (39%), Positives = 23/38 (60%)
Query: 1156 KSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKR 1193
+ RQE R+ +EE +EE L E+ RRQE+E++
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ 1198
Score = 32.3 bits (72), Expect = 2.8
Identities = 17/64 (26%), Positives = 32/64 (50%), Gaps = 9/64 (14%)
Query: 1158 RQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPL---------GSVRSTKIYTPG 1208
R+E +R +E EE L ++ + R +++++RS L +VR K+Y G
Sbjct: 1185 REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG 1244
Query: 1209 RKEQ 1212
R+ +
Sbjct: 1245 RENE 1248
Score = 32.0 bits (71), Expect = 3.7
Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
Query: 1156 KSRQE-NRRRAKEEASAMEEEMALAEEQLRARRQEQEKR 1193
+ RQE R+ KEE EEE L EE + RRQE+E++
Sbjct: 1071 RRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQ 1109
Score = 30.8 bits (68), Expect = 8.3
Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
Query: 1156 KSRQENRRRAKEEASAM-EEEMALAEEQLRARRQEQEKR 1193
+ RQE ++ +EE EEE L EE+ + RRQE E++
Sbjct: 981 RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 64.3 bits (155), Expect = 7e-10
Identities = 41/207 (19%), Positives = 95/207 (45%), Gaps = 7/207 (3%)
Query: 55 ASLKRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSAR 114
+ ++ RERE + E KK+ + K+ E + +++ E+E + G+ +K + R
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95
Query: 115 VETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERD 174
++E E+ +++++E++E G + +E++ K+E+ R+ +R+R ++ER+
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 175 RSR---HSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWE 231
+ R + ER E+ R E E + ++ R E R + E
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK----ERRERKKE 211
Query: 232 SPSPTPSYRDSERSHRLSTRDRDRSVR 258
++ ++ + + R+++R R
Sbjct: 212 RKKKEERKKERQKDRQTNWREKERGKR 238
Score = 53.9 bits (128), Expect = 9e-07
Identities = 36/139 (25%), Positives = 74/139 (53%), Gaps = 10/139 (7%)
Query: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
KR+++E+K+ G K+ K K+ E ++++K+ E + ++ + RK+R R +
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKE-ERKREERKERERKKEEREKERERKERKKRERKQV- 171
Query: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDR-DERDRS 176
G EE + ++ER++RE K+E++ K+ + R ++ +K +R ER +
Sbjct: 172 -----GEKEEERKEKERKERKKRERN-RKERKKERERKERRERKKERKKKEERKKERQKD 225
Query: 177 RHSSRSERDGGS-ERSSRR 194
R ++ E++ G ER R+
Sbjct: 226 RQTNWREKERGKRERKERK 244
Score = 47.0 bits (110), Expect = 1e-04
Identities = 49/235 (20%), Positives = 92/235 (39%), Gaps = 25/235 (10%)
Query: 74 SKVSSYKDWE-ESKDDQKDAE--EEGGDQAGQNIRKDRHYRSARVETPSHPGGVSEEFWE 130
SK + W+ E ++ +++ E +EG + +K+R R +
Sbjct: 26 SKPCTQPGWQSEIREREREIETRKEGKKERESERKKERRERE-----------------K 68
Query: 131 RSRQRERER-REHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSSRSERDGGSE 189
R R+RE+ER RE G E K ++E+ + R ++ +E+++ + + ER S+
Sbjct: 69 RKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSK 128
Query: 190 RSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYRDSERSHRLS 249
R E + + + E+E +R + + ++ ER R
Sbjct: 129 EGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER-K 187
Query: 250 TRDRDRSVRGK---YSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEGE 301
R+R+R R K + K E +R+ T + RG+RE E
Sbjct: 188 KRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 33.5 bits (75), Expect = 1.3
Identities = 44/217 (20%), Positives = 88/217 (40%), Gaps = 24/217 (11%)
Query: 315 WEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINEDN 374
W+ + R+ +R+ EG E SE RRE+ K+K++R ++R+ +
Sbjct: 34 WQSEIREREREIETRKEGKKE------RESERKKERRERE--KRKREREKERKRERGKKE 85
Query: 375 ERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVK 434
++ E + R E + E+ + +G+ K+ K
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
Query: 435 DATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMGVKKEEE-PDKAVTE 493
+ + + K RE+KERKK + K ++G+ +KE+E ++ E
Sbjct: 146 ER--------ERKKEEREKERERKERKKRERK-------QVGEKEEERKEKERKERKKRE 190
Query: 494 DGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQ 530
+ + + E++ + +RK E + +KK + RQ
Sbjct: 191 RNRKERKKERERKERRERKKERKKKEERKKERQKDRQ 227
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,460,573
Number of Sequences: 37866
Number of extensions: 2449952
Number of successful extensions: 25347
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 267
Number of HSP's successfully gapped in prelim test: 519
Number of HSP's that attempted gapping in prelim test: 13511
Number of HSP's gapped (non-prelim): 6627
length of query: 1227
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1113
effective length of database: 13,930,794
effective search space: 15504973722
effective search space used: 15504973722
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.