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Search of human proteins with 17505234
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17505234 nucleolar and spindle associated protein 1 isoform
2 [Homo sapiens]
(440 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17505234 nucleolar and spindle associated protein 1 isoform 2... 875 0.0
gi|193804865 nucleolar and spindle associated protein 1 isoform ... 870 0.0
gi|193804867 nucleolar and spindle associated protein 1 isoform ... 773 0.0
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 44 2e-04
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 42 0.001
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 42 0.001
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 42 0.001
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 42 0.001
gi|87162461 fragile X mental retardation 2 [Homo sapiens] 41 0.002
gi|125656165 THO complex 2 [Homo sapiens] 39 0.012
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 39 0.012
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 39 0.012
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 39 0.012
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 39 0.012
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 38 0.016
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 38 0.016
gi|61097912 nucleolar protein with MIF4G domain 1 [Homo sapiens] 38 0.016
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 38 0.021
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 38 0.021
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 38 0.021
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 38 0.021
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 38 0.021
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 37 0.027
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 37 0.027
gi|223278374 DNA cross-link repair 1A [Homo sapiens] 37 0.027
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 37 0.027
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 37 0.027
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s... 37 0.027
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa... 37 0.027
gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens] 37 0.027
>gi|17505234 nucleolar and spindle associated protein 1 isoform 2
[Homo sapiens]
Length = 440
Score = 875 bits (2260), Expect = 0.0
Identities = 440/440 (100%), Positives = 440/440 (100%)
Query: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS
Sbjct: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
Query: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE
Sbjct: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI
Sbjct: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
Query: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQPINKGGVRTPVPPRGRLSV 240
TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQPINKGGVRTPVPPRGRLSV
Sbjct: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQPINKGGVRTPVPPRGRLSV 240
Query: 241 ASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTP 300
ASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTP
Sbjct: 241 ASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTP 300
Query: 301 ARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLK 360
ARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLK
Sbjct: 301 ARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLK 360
Query: 361 ASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQE 420
ASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQE
Sbjct: 361 ASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQE 420
Query: 421 RKEKKAKVLGMRRGLILAED 440
RKEKKAKVLGMRRGLILAED
Sbjct: 421 RKEKKAKVLGMRRGLILAED 440
>gi|193804865 nucleolar and spindle associated protein 1 isoform 1
[Homo sapiens]
Length = 441
Score = 870 bits (2248), Expect = 0.0
Identities = 440/441 (99%), Positives = 440/441 (99%), Gaps = 1/441 (0%)
Query: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS
Sbjct: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
Query: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE
Sbjct: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI
Sbjct: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
Query: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELK-QPINKGGVRTPVPPRGRLS 239
TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELK QPINKGGVRTPVPPRGRLS
Sbjct: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240
Query: 240 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 299
VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT
Sbjct: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300
Query: 300 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL 359
PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL
Sbjct: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL 360
Query: 360 KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 419
KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ
Sbjct: 361 KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 420
Query: 420 ERKEKKAKVLGMRRGLILAED 440
ERKEKKAKVLGMRRGLILAED
Sbjct: 421 ERKEKKAKVLGMRRGLILAED 441
>gi|193804867 nucleolar and spindle associated protein 1 isoform 3
[Homo sapiens]
Length = 402
Score = 773 bits (1996), Expect = 0.0
Identities = 401/441 (90%), Positives = 401/441 (90%), Gaps = 40/441 (9%)
Query: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS
Sbjct: 1 MIIPSLEELDSLKYSDLQNLAKSLGLRANLRATKLLKALKGYIKHEARKGNENQDESQTS 60
Query: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE
Sbjct: 61 ASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHE 120
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI
Sbjct: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAI 180
Query: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELK-QPINKGGVRTPVPPRGRLS 239
TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELK QPINKGGVRTPVPPRGRLS
Sbjct: 181 TTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQQPINKGGVRTPVPPRGRLS 240
Query: 240 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 299
VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT
Sbjct: 241 VASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKT 300
Query: 300 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDL 359
PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAA
Sbjct: 301 PARKSAHVTVSGGTPKGEAVLGTHKLKTITGNSAA------------------------- 335
Query: 360 KASLSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 419
GKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ
Sbjct: 336 --------------GKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQ 381
Query: 420 ERKEKKAKVLGMRRGLILAED 440
ERKEKKAKVLGMRRGLILAED
Sbjct: 382 ERKEKKAKVLGMRRGLILAED 402
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 44.3 bits (103), Expect = 2e-04
Identities = 52/206 (25%), Positives = 84/206 (40%), Gaps = 20/206 (9%)
Query: 95 VRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDS 154
VR PD +Q H ++ S P + H+ + RA A+ P E+ N + N S
Sbjct: 1230 VRAGPDRRQ-HPSLESSYPPDL--HKSSPHGEKRAHARDPKGSREYSRQPNEHHTWNGTS 1286
Query: 155 KVPSEG--KKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEE 212
+ P G + E + + +R A ++ E + S D +ER++KH +
Sbjct: 1287 RKPDSGACRPKDRAPEGRRDAQAERAAAANGPKRRSPEKRREGTRSADNTLERREKHEKR 1346
Query: 213 HNSMNELKQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRS 272
+ E ++ + R P R R S+ + QRRS R G GS +R
Sbjct: 1347 RDVSPERRRERSPTRRRDGSPSRRRRSLERL-LEQRRSPERRRG----------GSPER- 1394
Query: 273 AISAAKTGVRFSAATKDNEHKRSLTK 298
AK+ R A + + +RSL K
Sbjct: 1395 ---RAKSTDRRRARSPERRRERSLDK 1417
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 42.0 bits (97), Expect = 0.001
Identities = 86/423 (20%), Positives = 159/423 (37%), Gaps = 45/423 (10%)
Query: 29 NLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETE----IQISNQEEAERQPLGH 84
+L K+ + +G + E++++ S + D+T+ + +N + P+
Sbjct: 249 SLEQEKVDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAV 308
Query: 85 VTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEK--------QESQDLRATAKVPSP 136
T T + P + + KIS E + E +++ A A++ +
Sbjct: 309 TTPTVSSGQATPTSPIKKFPTTATKISPKEEERKDESPATWRLGLRKTGSYGALAEITAS 368
Query: 137 PDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKK--LHEAHFK 194
+ +E + A + + S S SL E K K R A P + + +
Sbjct: 369 KEGQKEKDTAGVTRSASSPRLSS---SLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIE 425
Query: 195 EMESIDQYIERKKKHFEEHNSMNELKQ--PINKGGVRTPVPPRGRLS--VASTPISQRRS 250
E E+ D R + ++LK+ +N+G GR + S+ + S
Sbjct: 426 EKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTS 485
Query: 251 QGRSCGPASQSTLGLKGSLKRSAISAAK-TGVRFSAATKDNEHKRSLTKTPARKSAHVTV 309
P S GL+ SL S + K T SA T+ + R + K
Sbjct: 486 T-----PTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVP 540
Query: 310 SGGT-PKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLN 368
+ T P V+ N+AA T TT T VS+ V + + S P+
Sbjct: 541 TAVTIPVAPTVV----------NAAASTTTLTTTTAGT---VSSTTEVRERRRSYLTPVR 587
Query: 369 YEPHKGKLKPWG-QSKENNYLNQHVNRINFY---KKTYKQPHLQTKEEQRKKREQERKEK 424
E + + K Q++++ Q V + K + +T+E++ +++E+E KEK
Sbjct: 588 DEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEK 647
Query: 425 KAK 427
+ K
Sbjct: 648 QDK 650
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 42.0 bits (97), Expect = 0.001
Identities = 86/423 (20%), Positives = 159/423 (37%), Gaps = 45/423 (10%)
Query: 29 NLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETE----IQISNQEEAERQPLGH 84
+L K+ + +G + E++++ S + D+T+ + +N + P+
Sbjct: 336 SLEQEKVDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAV 395
Query: 85 VTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEK--------QESQDLRATAKVPSP 136
T T + P + + KIS E + E +++ A A++ +
Sbjct: 396 TTPTVSSGQATPTSPIKKFPTTATKISPKEEERKDESPATWRLGLRKTGSYGALAEITAS 455
Query: 137 PDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKK--LHEAHFK 194
+ +E + A + + S S SL E K K R A P + + +
Sbjct: 456 KEGQKEKDTAGVTRSASSPRLSS---SLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIE 512
Query: 195 EMESIDQYIERKKKHFEEHNSMNELKQ--PINKGGVRTPVPPRGRLS--VASTPISQRRS 250
E E+ D R + ++LK+ +N+G GR + S+ + S
Sbjct: 513 EKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTS 572
Query: 251 QGRSCGPASQSTLGLKGSLKRSAISAAK-TGVRFSAATKDNEHKRSLTKTPARKSAHVTV 309
P S GL+ SL S + K T SA T+ + R + K
Sbjct: 573 T-----PTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVP 627
Query: 310 SGGT-PKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLN 368
+ T P V+ N+AA T TT T VS+ V + + S P+
Sbjct: 628 TAVTIPVAPTVV----------NAAASTTTLTTTTAGT---VSSTTEVRERRRSYLTPVR 674
Query: 369 YEPHKGKLKPWG-QSKENNYLNQHVNRINFY---KKTYKQPHLQTKEEQRKKREQERKEK 424
E + + K Q++++ Q V + K + +T+E++ +++E+E KEK
Sbjct: 675 DEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEK 734
Query: 425 KAK 427
+ K
Sbjct: 735 QDK 737
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 42.0 bits (97), Expect = 0.001
Identities = 86/423 (20%), Positives = 159/423 (37%), Gaps = 45/423 (10%)
Query: 29 NLRATKLLKALKGYIKHEARKGNENQDESQTSASSCDETE----IQISNQEEAERQPLGH 84
+L K+ + +G + E++++ S + D+T+ + +N + P+
Sbjct: 336 SLEQEKVDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAV 395
Query: 85 VTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEK--------QESQDLRATAKVPSP 136
T T + P + + KIS E + E +++ A A++ +
Sbjct: 396 TTPTVSSGQATPTSPIKKFPTTATKISPKEEERKDESPATWRLGLRKTGSYGALAEITAS 455
Query: 137 PDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKK--LHEAHFK 194
+ +E + A + + S S SL E K K R A P + + +
Sbjct: 456 KEGQKEKDTAGVTRSASSPRLSS---SLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIE 512
Query: 195 EMESIDQYIERKKKHFEEHNSMNELKQ--PINKGGVRTPVPPRGRLS--VASTPISQRRS 250
E E+ D R + ++LK+ +N+G GR + S+ + S
Sbjct: 513 EKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTS 572
Query: 251 QGRSCGPASQSTLGLKGSLKRSAISAAK-TGVRFSAATKDNEHKRSLTKTPARKSAHVTV 309
P S GL+ SL S + K T SA T+ + R + K
Sbjct: 573 T-----PTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVP 627
Query: 310 SGGT-PKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLN 368
+ T P V+ N+AA T TT T VS+ V + + S P+
Sbjct: 628 TAVTIPVAPTVV----------NAAASTTTLTTTTAGT---VSSTTEVRERRRSYLTPVR 674
Query: 369 YEPHKGKLKPWG-QSKENNYLNQHVNRINFY---KKTYKQPHLQTKEEQRKKREQERKEK 424
E + + K Q++++ Q V + K + +T+E++ +++E+E KEK
Sbjct: 675 DEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEK 734
Query: 425 KAK 427
+ K
Sbjct: 735 QDK 737
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 42.0 bits (97), Expect = 0.001
Identities = 86/400 (21%), Positives = 148/400 (37%), Gaps = 38/400 (9%)
Query: 33 TKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRC 92
T ++ G I E K E +++ S ++ E + + EAER L + R R
Sbjct: 223 TVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLE--AEERERI 280
Query: 93 KTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDL-RATAKVPSPPDEHQEAENAVSSGN 151
K + D + I+ Q E++E+++ R + +E Q +
Sbjct: 281 KAEQ-DKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAA 339
Query: 152 RDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFK-EMESIDQYIERKKKHF 210
+ + E +K + + KR A + E K E + ++ +E KK
Sbjct: 340 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAM 399
Query: 211 EEHNSMNE-LKQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSL 269
+E E ++Q I V +L A + QG G Q+ + L
Sbjct: 400 QETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVL-----KKQGEEKGTKVQAK---REKL 451
Query: 270 KRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLK--- 326
+ + K ++ KD E K + RK V + GE + THKLK
Sbjct: 452 QEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK--SQNGEFM--THKLKHTE 507
Query: 327 ---TITGNSAAVITPFKLTTEATQTP-VSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQS 382
+ G A+V T EA P V K + +L+ + E K K K +
Sbjct: 508 NTFSRPGGRASVDTK-----EAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAA 562
Query: 383 KENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERK 422
E L + K+ ++ L+ +E++RK+ E +RK
Sbjct: 563 LELEELKK--------KREERRKVLEEEEQRRKQEEADRK 594
Score = 29.6 bits (65), Expect = 5.7
Identities = 37/163 (22%), Positives = 64/163 (39%), Gaps = 23/163 (14%)
Query: 44 KHEARKGNENQDESQTSASSCD----ETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDP 99
K E R+ ++E + D E E + +EE ER+ + R++ +
Sbjct: 571 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR-AEAAEKRQKMPEDGLSD 629
Query: 100 DSQQ------NHSEIKISNPTEFQNHEKQESQDLRAT--AKVPSPPDEHQEAENAVSSGN 151
D + S +KI EF N Q+S +++T A + S D E + G
Sbjct: 630 DKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGT 689
Query: 152 RDSK----------VPSEGKKSLYTDESSKPGKNKRTAITTPN 184
+ +K VP+EG +++ + + TA TPN
Sbjct: 690 KSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPN 732
>gi|87162461 fragile X mental retardation 2 [Homo sapiens]
Length = 1311
Score = 41.2 bits (95), Expect = 0.002
Identities = 84/399 (21%), Positives = 143/399 (35%), Gaps = 47/399 (11%)
Query: 46 EARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNH 105
+A G+ + ES++S+ S +TE ++ E E R T +P S
Sbjct: 479 QASGGSGSSSESESSSESDSDTESSTTDSESNEAP----------RVATPEPEPPSTNKW 528
Query: 106 SEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLY 165
K N QN Q+ + PP Q E + S+VP+E K+
Sbjct: 529 QLDKWLNKVTSQNKSFICGQNETPMETISLPPPIIQPMEVQMKVKTNASQVPAEPKERPL 588
Query: 166 TD---ESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKK--KHFEEHNSMNEL- 219
E ++P R P K L E++ Q KK K E++ S +E
Sbjct: 589 LSLIREKARP----RPTQKIPETKALKHKLSTTSETVSQRTIGKKQPKKVEKNTSTDEFT 644
Query: 220 --------KQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKR 271
P K V PPRGR + A+ R + R P + +G K
Sbjct: 645 WPKPNITSSTPKEKESVELHDPPRGR-NKATAHKPAPRKEPRPNIPLAPEKKKYRGPGK- 702
Query: 272 SAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTITGN 331
+ ++ + ++T D+ + T + +SGG T K K I G
Sbjct: 703 -IVPKSREFIETDSSTSDSNTDQEET-LQIKVLPPCIISGG--------NTAKSKEICGA 752
Query: 332 SAAVITPFKLTTEATQTPVSNKKPVFD----LKASLSRPLNYEPHKGKLKPWGQSKENNY 387
S + T + +SN++P F ++ + PL H+ W + + +
Sbjct: 753 SLTLSTLMSSSGSNNNLSISNEEPTFSPIPVMQTEILSPL--RDHENLKNLWVKI-DLDL 809
Query: 388 LNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKA 426
L++ + + K H +T + +++ EK A
Sbjct: 810 LSRVPGHSSLHAAPAKPDHKETATKPKRQTAVTAVEKPA 848
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 38.5 bits (88), Expect = 0.012
Identities = 81/399 (20%), Positives = 148/399 (37%), Gaps = 42/399 (10%)
Query: 50 GNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIK 109
G S SAS DE+ + +++ ER G K + + +S +S
Sbjct: 1205 GGGPSSSSIGSASKSDESSTEETDKSR-ERSQCG--VKAVNKASSTTPKGNSSNGNSGSN 1261
Query: 110 ISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDES 169
+ + + EK + ++ K P+ E + + +GK+ +
Sbjct: 1262 SNKAVKENDKEKGKEKEKEKKEKTPATTPEARV-------------LGKDGKEKPKEERP 1308
Query: 170 SKPGKNKRTAITTPNFKKLHEAHFKEMESID---------------QYIERKKKHFEEHN 214
+K K + T TP K E KE ++ D Q ER+K+ E +
Sbjct: 1309 NKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERD 1368
Query: 215 SMNELKQPIN-KGGVRTPVPPRGRLSVASTPISQ-RRSQGR---SCGPASQSTLGLKGSL 269
E+K N KGG +TPV + V + I + R Q R P+ + +K SL
Sbjct: 1369 IAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSSTVKDSL 1428
Query: 270 KRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKSAHVTVSGGTPKGEAVLGTHKLKTIT 329
S+AK + + +R + K KS S K + + + +
Sbjct: 1429 IELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRE--RSREREKKDEKDRKERKRDHS 1486
Query: 330 GNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSK-ENNYL 388
N V + + K + P + K K K G+ K +++
Sbjct: 1487 NNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFK 1546
Query: 389 NQHVNRINFYKKTYKQPHLQTKEEQRKKREQE--RKEKK 425
++ +++I+ K + H + K E+++KR+ ++EKK
Sbjct: 1547 SEKMDKISSGGKK-ESRHDKEKIEKKEKRDSSGGKEEKK 1584
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 38.5 bits (88), Expect = 0.012
Identities = 71/336 (21%), Positives = 115/336 (34%), Gaps = 54/336 (16%)
Query: 42 YIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPD- 100
Y+ H R E +E Q +E +++ E A R+ +TK +R T DP+
Sbjct: 33 YLAHSGRSHLE-PEEKQALKRLVEEELLKMQVDEAASREDKLDLTKKGKRPPTPCSDPER 91
Query: 101 -----SQQNHSEIKISNPTEFQNHEK----------QESQDLRATAKVPSPPDEHQEAEN 145
+ ++ S + S+P F K +E RA+ V DE ++ +
Sbjct: 92 KRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEESSDEERQRDL 151
Query: 146 AVSSGNRDSKVPSEG-----------------------KKSLYTDESSKPGKNKRTAITT 182
G S+ +G K++ E S+ +RTA
Sbjct: 152 PAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEESEAEPVQRTAKKV 211
Query: 183 PNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQPINKGGVRTPVPPRGRLSVAS 242
K E ES ++ + +KK+ EE E ++ KG + GR A
Sbjct: 212 EGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSA- 270
Query: 243 TPISQRRSQGRSCGPASQSTLGLKGS-----LKRSAISAAKTGVRFSAATKDNEHKRSLT 297
+ RSC SQ+ L S K +A S +G + R+
Sbjct: 271 -------REERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQL 323
Query: 298 KTPARKSAHVTVSGGTPKGE-AVLGTHKLKTITGNS 332
K R S + KGE G+ K+ + S
Sbjct: 324 KGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTS 359
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 38.5 bits (88), Expect = 0.012
Identities = 62/345 (17%), Positives = 121/345 (35%), Gaps = 49/345 (14%)
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYT-------------- 166
K + +++ K P D+ +++ ++ S D + P +G KS +T
Sbjct: 1127 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP-QGAKSAHTLGPTPSRTETLVEE 1185
Query: 167 -------DESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQY--IERKKKHFEEHNSMN 217
D+ P ++ + TP + K +D + ++ +
Sbjct: 1186 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1245
Query: 218 ELKQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGS--------- 268
E K P G+ +P + +TP R+ + + G STL L+ +
Sbjct: 1246 EAK-PQQAAGMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQSNITQCLLGQP 1303
Query: 269 --LKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARK---SAHVTVSGGTPKGEAVLGTH 323
L + + A+ V ++ + TK +RK S +SG P
Sbjct: 1304 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1363
Query: 324 KLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSK 383
K K G + T+ ++ K D+K KG L G
Sbjct: 1364 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--------KGSLGSQGAKD 1415
Query: 384 E-NNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 427
E L + + + ++ + + K+ ++K+++E+KEKK K
Sbjct: 1416 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1460
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 38.5 bits (88), Expect = 0.012
Identities = 62/345 (17%), Positives = 121/345 (35%), Gaps = 49/345 (14%)
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYT-------------- 166
K + +++ K P D+ +++ ++ S D + P +G KS +T
Sbjct: 1050 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP-QGAKSAHTLGPTPSRTETLVEE 1108
Query: 167 -------DESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQY--IERKKKHFEEHNSMN 217
D+ P ++ + TP + K +D + ++ +
Sbjct: 1109 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1168
Query: 218 ELKQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGS--------- 268
E K P G+ +P + +TP R+ + + G STL L+ +
Sbjct: 1169 EAK-PQQAAGMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQSNITQCLLGQP 1226
Query: 269 --LKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARK---SAHVTVSGGTPKGEAVLGTH 323
L + + A+ V ++ + TK +RK S +SG P
Sbjct: 1227 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1286
Query: 324 KLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSK 383
K K G + T+ ++ K D+K KG L G
Sbjct: 1287 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--------KGSLGSQGAKD 1338
Query: 384 E-NNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 427
E L + + + ++ + + K+ ++K+++E+KEKK K
Sbjct: 1339 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1383
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 38.5 bits (88), Expect = 0.012
Identities = 62/345 (17%), Positives = 121/345 (35%), Gaps = 49/345 (14%)
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYT-------------- 166
K + +++ K P D+ +++ ++ S D + P +G KS +T
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP-QGAKSAHTLGPTPSRTETLVEE 1147
Query: 167 -------DESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQY--IERKKKHFEEHNSMN 217
D+ P ++ + TP + K +D + ++ +
Sbjct: 1148 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1207
Query: 218 ELKQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGS--------- 268
E K P G+ +P + +TP R+ + + G STL L+ +
Sbjct: 1208 EAK-PQQAAGMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQSNITQCLLGQP 1265
Query: 269 --LKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARK---SAHVTVSGGTPKGEAVLGTH 323
L + + A+ V ++ + TK +RK S +SG P
Sbjct: 1266 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1325
Query: 324 KLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQSK 383
K K G + T+ ++ K D+K KG L G
Sbjct: 1326 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--------KGSLGSQGAKD 1377
Query: 384 E-NNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 427
E L + + + ++ + + K+ ++K+++E+KEKK K
Sbjct: 1378 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1422
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 38.1 bits (87), Expect = 0.016
Identities = 62/346 (17%), Positives = 121/346 (34%), Gaps = 50/346 (14%)
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYT-------------- 166
K + +++ K P D+ +++ ++ S D + P +G KS +T
Sbjct: 1050 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP-QGAKSAHTLVGPTPSRTETLVE 1108
Query: 167 --------DESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQY--IERKKKHFEEHNSM 216
D+ P ++ + TP + K +D + ++ +
Sbjct: 1109 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1168
Query: 217 NELKQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGS-------- 268
E K P G+ +P + +TP R+ + + G STL L+ +
Sbjct: 1169 QEAK-PQQAAGMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQSNITQCLLGQ 1226
Query: 269 ---LKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARK---SAHVTVSGGTPKGEAVLGT 322
L + + A+ V ++ + TK +RK S +SG P
Sbjct: 1227 PWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1286
Query: 323 HKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQS 382
K K G + T+ ++ K D+K KG L G
Sbjct: 1287 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--------KGSLGSQGAK 1338
Query: 383 KE-NNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 427
E L + + + ++ + + K+ ++K+++E+KEKK K
Sbjct: 1339 DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1384
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 38.1 bits (87), Expect = 0.016
Identities = 62/346 (17%), Positives = 121/346 (34%), Gaps = 50/346 (14%)
Query: 121 KQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYT-------------- 166
K + +++ K P D+ +++ ++ S D + P +G KS +T
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP-QGAKSAHTLVGPTPSRTETLVE 1147
Query: 167 --------DESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQY--IERKKKHFEEHNSM 216
D+ P ++ + TP + K +D + ++ +
Sbjct: 1148 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1207
Query: 217 NELKQPINKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGS-------- 268
E K P G+ +P + +TP R+ + + G STL L+ +
Sbjct: 1208 QEAK-PQQAAGMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQSNITQCLLGQ 1265
Query: 269 ---LKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARK---SAHVTVSGGTPKGEAVLGT 322
L + + A+ V ++ + TK +RK S +SG P
Sbjct: 1266 PWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1325
Query: 323 HKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKASLSRPLNYEPHKGKLKPWGQS 382
K K G + T+ ++ K D+K KG L G
Sbjct: 1326 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--------KGSLGSQGAK 1377
Query: 383 KE-NNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERKEKKAK 427
E L + + + ++ + + K+ ++K+++E+KEKK K
Sbjct: 1378 DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1423
>gi|61097912 nucleolar protein with MIF4G domain 1 [Homo sapiens]
Length = 860
Score = 38.1 bits (87), Expect = 0.016
Identities = 40/174 (22%), Positives = 72/174 (41%), Gaps = 35/174 (20%)
Query: 50 GNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIK 109
G E +D QT E++++ +Q+E+E + G V K ++ + SE
Sbjct: 236 GEEEEDAGQT----LPESDLESDSQDESEEEEEGDVEKEKK--------AQEAEAQSEDD 283
Query: 110 ISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGN-RDSKVPSEGKKSLYTDE 168
+ E Q EK++ + K ++ +++EN+ G+ D + G+K +
Sbjct: 284 DEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSSEDGDITDKSLCGSGEKYI---- 339
Query: 169 SSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKHFEEHNSMNELKQP 222
+ R A T +FKK E +ER KKH + +N L +P
Sbjct: 340 ----PPHVRQAEETVDFKKKEE------------LERLKKHVK--GLLNRLSEP 375
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 37.7 bits (86), Expect = 0.021
Identities = 46/215 (21%), Positives = 84/215 (39%), Gaps = 24/215 (11%)
Query: 59 TSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQN 118
T + +E + S+ EE + + + TK + K P Q S+ ++ +
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSS 477
Query: 119 HEKQESQDLRATAK----------VPSPPDEHQE--AENAVSSGNRDSKVPSEGK-KSLY 165
E++E + ++ K PS P ++ AE++ SS + DS E K K
Sbjct: 478 SEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKG 537
Query: 166 TDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKKH---FEEHNSMNELKQP 222
+ P N +A+T N K + +E E KKK + S+ + KQ
Sbjct: 538 SPRPQAPKANGTSALTAQNGKAAKNSEEEE--------EEKKKAAVVVSKSGSLKKRKQN 589
Query: 223 INKGGVRTPVPPRGRLSVASTPISQRRSQGRSCGP 257
TP + +L +T +++ + R+ P
Sbjct: 590 EAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSP 624
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 37.7 bits (86), Expect = 0.021
Identities = 47/216 (21%), Positives = 89/216 (41%), Gaps = 28/216 (12%)
Query: 32 ATKLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEE------------AER 79
A K K +K +K + +K + +D T A S D + + +++ ++
Sbjct: 306 AKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKK 365
Query: 80 QPLGHVTKT---------RRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRAT 130
P T++ R K + D +++ +I S +E + K+ +D +
Sbjct: 366 YPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKD 425
Query: 131 AKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHE 190
K S D + +N S + DS+ + KK ++ K K+ + + KK
Sbjct: 426 KK-DSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGK--KDSKKDDKKKDAKK--N 480
Query: 191 AHFKEMESIDQYIERKKKHF-EEHNSMNELKQPINK 225
A EMES D +++ KKH E+ S ++K+ K
Sbjct: 481 AESTEMES-DLELKKDKKHSKEKKGSKKDIKKDARK 515
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 37.7 bits (86), Expect = 0.021
Identities = 39/196 (19%), Positives = 79/196 (40%), Gaps = 24/196 (12%)
Query: 44 KHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQ 103
+ E K + ++E + + + ++ EI+ + +EE + + H + + + + Q+
Sbjct: 306 EQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQ------EEEEQK 359
Query: 104 NHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPD--EHQEAENAVSSGNR-DSKVPSEG 160
E+K+ TE + EKQ+ V + +H A+ V NR +S PSE
Sbjct: 360 QEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSEN 419
Query: 161 KKSLYTD-------------ESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKK 207
+ S + +S PGK +A+ K+ E KE E + + + +
Sbjct: 420 EASKELEPEMEFEIEPDKECKSLSPGKENVSALDME--KESEEKEEKESEPQPEPVAQPQ 477
Query: 208 KHFEEHNSMNELKQPI 223
+ + QP+
Sbjct: 478 PQSQPQLQLQSQSQPV 493
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 37.7 bits (86), Expect = 0.021
Identities = 49/255 (19%), Positives = 95/255 (37%), Gaps = 46/255 (18%)
Query: 86 TKTRRRCKTVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSP-PDEHQEAE 144
T+ R K+ P S + S PT+ H + + P+P P H+E
Sbjct: 400 TRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPK-----PAPAPGSHREIS 454
Query: 145 NAVSSGNRD----------SKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFK 194
++ +S NR S PS + ++K G+++ T + ++
Sbjct: 455 SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR 514
Query: 195 EMESIDQY-------------------------IERKKKHFEEHNSMNELKQPINKGGVR 229
S ++ +R+ + + + P +G R
Sbjct: 515 RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSR 574
Query: 230 TPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATKD 289
+ P R S + TP ++RRS+ R+ P + + + R S ++T R + T+
Sbjct: 575 SRTPARRGRSRSRTP-ARRRSRSRT--PTRRRSRSRTPA--RRGRSRSRTPARRRSRTRS 629
Query: 290 NEHKRSLTKTPARKS 304
+RS +++PAR+S
Sbjct: 630 PVRRRSRSRSPARRS 644
Score = 33.5 bits (75), Expect = 0.39
Identities = 57/235 (24%), Positives = 86/235 (36%), Gaps = 51/235 (21%)
Query: 108 IKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTD 167
+K NP + +HE++ +LR E E KV + + + +
Sbjct: 50 VKRPNP-DILDHERKRRVELRCLEL------EEMMEEQGYEEQQIQEKVATF--RLMLLE 100
Query: 168 ESSKPGKNKRTAITTPNFKKLH---EAHFKEMESI-------DQYIERKKKHFEEHNSMN 217
+ PG + T P + H E + K+ E + D Y++ F+
Sbjct: 101 KDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSS--FDPQRRAR 158
Query: 218 ELKQPI-----------NKGGVRTPVPP---------RGRLSVASTPISQRRSQGRSCGP 257
E KQP R+P P RGR S +S+P +R+ +
Sbjct: 159 EAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKH 218
Query: 258 ASQSTLGLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTPARKS--AHVTVS 310
S+S S KR S R S KD + KRS + TPA KS AH + S
Sbjct: 219 RSESE-----SKKRKHRSPTPKSKRKS---KDKKRKRSRSTTPAPKSRRAHRSTS 265
Score = 29.3 bits (64), Expect = 7.4
Identities = 36/151 (23%), Positives = 55/151 (36%), Gaps = 24/151 (15%)
Query: 129 ATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKL 188
A P PP + + SS S P + KK K + +R+ ++P ++
Sbjct: 160 AKQPAPEPPKPYSLVRESSSSR---SPTPKQKKKK------KKKDRGRRSESSSPRRERK 210
Query: 189 HEAHFKEMESIDQYIERKKKHFEEHNSMNELKQPINKGGVRTPVPPRGRLSVASTPISQR 248
+ +KKKH E S + R + + S ++TP +
Sbjct: 211 KSS-------------KKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKS 257
Query: 249 RSQGRSCGPASQSTLGLKGSLKRSAISAAKT 279
R RS S S+ S RSA AAKT
Sbjct: 258 RRAHRSTSADSASSSDTSRSRSRSA--AAKT 286
Score = 28.9 bits (63), Expect = 9.7
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 8/76 (10%)
Query: 229 RTPVPPRGRLSVASTPISQRRSQGRSCGPASQSTLGLKGSLKRSAISAAKTGVRFSAATK 288
RTP+ R R ++P+S+RRS+ R+ S + + S +S ++ R T+
Sbjct: 1879 RTPLISRRRSRSRTSPVSRRRSRSRT------SVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
Query: 289 DNEHKRSLTKTPARKS 304
RS T T R+S
Sbjct: 1933 --RRSRSRTPTTRRRS 1946
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 37.7 bits (86), Expect = 0.021
Identities = 78/423 (18%), Positives = 144/423 (34%), Gaps = 54/423 (12%)
Query: 44 KHEARKGNENQDES-QTSASSCDETEIQISNQE-EAERQPLGHVTKTRRRCKTVRVDPDS 101
+HE K + + E + + DE + Q +++ E ER+ K + + K P S
Sbjct: 439 EHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKERE------KEKGKPKPRSPQPPS 492
Query: 102 QQNHSEIKISNPTEFQNHEKQESQDLRATAKVP--------SPPDEHQEAENAVSSGNRD 153
+Q K + T Q E +D +K P SP + + + SS +
Sbjct: 493 RQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASAS 552
Query: 154 SKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEMESIDQYIERKKK----- 208
+ S + S Y+ S +++ ++ ++ + + + F S +
Sbjct: 553 NSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTP 612
Query: 209 --HFEEHNSMNELKQPINKGGVRT-------PVPPRGRLSVASTPI--------SQRRSQ 251
H + E P K G ++ P PP+ + A P RR +
Sbjct: 613 SPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKE 672
Query: 252 GRSCGPASQSTLGLKGSLKRSAISAAKTGVR---------FSAATKDNEHKRSLTKTPAR 302
+ P + TL GS S+ S + + R S+AT + S+
Sbjct: 673 RPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMY 732
Query: 303 KSAHVTVSGGTPKGEAVLGTHKLKTITGNSAAVITPFKLTTEATQTPVSNKKPVFDLKAS 362
VS + + A T K K + V + +TQ P S K P
Sbjct: 733 ADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPA------ 786
Query: 363 LSRPLNYEPHKGKLKPWGQSKENNYLNQHVNRINFYKKTYKQPHLQTKEEQRKKREQERK 422
+ +P + P GQ ++ ++ ++ K + + E K R+
Sbjct: 787 -GGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPP 845
Query: 423 EKK 425
K+
Sbjct: 846 AKR 848
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 37.4 bits (85), Expect = 0.027
Identities = 41/214 (19%), Positives = 85/214 (39%), Gaps = 35/214 (16%)
Query: 120 EKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDE--SSKPGKNKR 177
E++E ++ K +P + +E E G + + EG KS +E S K G +++
Sbjct: 502 EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEK 561
Query: 178 TAITTPNFKKLHEAHFKEMESIDQY-IERKKKHFEEHNSM---------NELKQPINKGG 227
+ EA +E E+ ++ +E K + + + K P+ K
Sbjct: 562 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSP 621
Query: 228 V---------RTPVPPRGRLSVASTPISQR----------RSQGRSCGPASQSTL--GLK 266
V ++PV +G+ V +P+ ++ +G+S P S+S + K
Sbjct: 622 VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS--PVSKSPVEEKAK 679
Query: 267 GSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTP 300
+ +S + AK+ + E ++ + + P
Sbjct: 680 SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP 713
Score = 30.0 bits (66), Expect = 4.4
Identities = 30/137 (21%), Positives = 55/137 (40%), Gaps = 7/137 (5%)
Query: 36 LKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTV 95
+KA +K E +G + ++E Q DE + EE + G K +
Sbjct: 513 VKATAPEVKEE--EGEKEEEEGQEEEEEEDEGA-KSDQAEEGGSEKEGSSEKEEGEQEEG 569
Query: 96 RVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSK 155
+ +++ +E K E ++ E ++L A AKV P ++A++ V + K
Sbjct: 570 ETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP----EKAKSPVPKSPVEEK 625
Query: 156 VPSEGKKSLYTDESSKP 172
S KS ++ P
Sbjct: 626 GKSPVPKSPVEEKGKSP 642
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 37.4 bits (85), Expect = 0.027
Identities = 41/214 (19%), Positives = 85/214 (39%), Gaps = 35/214 (16%)
Query: 120 EKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDE--SSKPGKNKR 177
E++E ++ K +P + +E E G + + EG KS +E S K G +++
Sbjct: 126 EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEK 185
Query: 178 TAITTPNFKKLHEAHFKEMESIDQY-IERKKKHFEEHNSM---------NELKQPINKGG 227
+ EA +E E+ ++ +E K + + + K P+ K
Sbjct: 186 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSP 245
Query: 228 V---------RTPVPPRGRLSVASTPISQR----------RSQGRSCGPASQSTL--GLK 266
V ++PV +G+ V +P+ ++ +G+S P S+S + K
Sbjct: 246 VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS--PVSKSPVEEKAK 303
Query: 267 GSLKRSAISAAKTGVRFSAATKDNEHKRSLTKTP 300
+ +S + AK+ + E ++ + + P
Sbjct: 304 SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP 337
Score = 30.0 bits (66), Expect = 4.4
Identities = 30/137 (21%), Positives = 55/137 (40%), Gaps = 7/137 (5%)
Query: 36 LKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTV 95
+KA +K E +G + ++E Q DE + EE + G K +
Sbjct: 137 VKATAPEVKEE--EGEKEEEEGQEEEEEEDEGA-KSDQAEEGGSEKEGSSEKEEGEQEEG 193
Query: 96 RVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSK 155
+ +++ +E K E ++ E ++L A AKV P ++A++ V + K
Sbjct: 194 ETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP----EKAKSPVPKSPVEEK 249
Query: 156 VPSEGKKSLYTDESSKP 172
S KS ++ P
Sbjct: 250 GKSPVPKSPVEEKGKSP 266
>gi|223278374 DNA cross-link repair 1A [Homo sapiens]
Length = 1040
Score = 37.4 bits (85), Expect = 0.027
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 17/134 (12%)
Query: 114 TEFQNHEKQESQDLRAT-----AKVPSPPDEHQEAENAVSSGNRDSKV------PSEGKK 162
T+F ++K LR +P P ++ + E + S D P + ++
Sbjct: 262 TDFVENDKLVGVALRLANNSEHINLPLPENDFSDCEISYSPLQSDEDTHDIDEKPDDSQE 321
Query: 163 SLYTDESSKPGKNKRTAITTPNFKKLHEAHFKEME----SIDQYIERKK--KHFEEHNSM 216
L+ ESSK G + + FKK H K+ + ++ ++ R K + NS+
Sbjct: 322 QLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDESCPKVNSFLTRDKYDEGLYRFNSL 381
Query: 217 NELKQPINKGGVRT 230
N+L QPI++ T
Sbjct: 382 NDLSQPISQNNEST 395
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 37.4 bits (85), Expect = 0.027
Identities = 30/146 (20%), Positives = 54/146 (36%), Gaps = 9/146 (6%)
Query: 34 KLLKALKGYIKHEARKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCK 93
+L ++KG IK +A + + + DE + SN + + R++C
Sbjct: 999 RLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDED-----EQRKKCA 1053
Query: 94 TVRVDPDSQQNHSEIKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRD 153
+ D D QN S + +P + + D ++ P Q +V SG
Sbjct: 1054 SSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSH 1113
Query: 154 SKVPSEGKK----SLYTDESSKPGKN 175
S V + S +D S+ G +
Sbjct: 1114 SGVSENDSRPASPSAESDHESERGSD 1139
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 37.4 bits (85), Expect = 0.027
Identities = 62/301 (20%), Positives = 116/301 (38%), Gaps = 52/301 (17%)
Query: 45 HEARKGNENQD--ESQTSASSCD----------ETEIQISNQEEAERQPLGHVTKTRRR- 91
HE + E +D ES A D E E I + E+ER+ + + RR
Sbjct: 413 HEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRR 472
Query: 92 ----CKTVRVDPDSQQNHSEIKISNPTE-------FQNHEKQESQDLRATAKVP------ 134
+++ + + ++ ++K N TE ++ EK+E++ L P
Sbjct: 473 IARDVNSIKKEIEEEKTEDKLK-DNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKK 531
Query: 135 ------SPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKL 188
S D +E E + +SK SEG++ E G + +K+
Sbjct: 532 IKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKI 591
Query: 189 HEAHFKEMESIDQYIERKKKH------FEEHNSMNELKQPINKGGVRTPVPPRGRLSVAS 242
+EA K E D + + ++E + + P++KGG + + + S
Sbjct: 592 YEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDS 651
Query: 243 TPISQR---RSQGRSCGPASQSTL--GLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLT 297
+R R + + P +STL + L ++A S K+ + + D+E + +L
Sbjct: 652 EKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS----DSCSSDSETEDALE 707
Query: 298 K 298
K
Sbjct: 708 K 708
>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
Length = 1203
Score = 37.4 bits (85), Expect = 0.027
Identities = 62/301 (20%), Positives = 116/301 (38%), Gaps = 52/301 (17%)
Query: 45 HEARKGNENQD--ESQTSASSCD----------ETEIQISNQEEAERQPLGHVTKTRRR- 91
HE + E +D ES A D E E I + E+ER+ + + RR
Sbjct: 413 HEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRR 472
Query: 92 ----CKTVRVDPDSQQNHSEIKISNPTE-------FQNHEKQESQDLRATAKVP------ 134
+++ + + ++ ++K N TE ++ EK+E++ L P
Sbjct: 473 IARDVNSIKKEIEEEKTEDKLK-DNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKK 531
Query: 135 ------SPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKL 188
S D +E E + +SK SEG++ E G + +K+
Sbjct: 532 IKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKI 591
Query: 189 HEAHFKEMESIDQYIERKKKH------FEEHNSMNELKQPINKGGVRTPVPPRGRLSVAS 242
+EA K E D + + ++E + + P++KGG + + + S
Sbjct: 592 YEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDS 651
Query: 243 TPISQR---RSQGRSCGPASQSTL--GLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLT 297
+R R + + P +STL + L ++A S K+ + + D+E + +L
Sbjct: 652 EKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS----DSCSSDSETEDALE 707
Query: 298 K 298
K
Sbjct: 708 K 708
>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
sapiens]
Length = 1257
Score = 37.4 bits (85), Expect = 0.027
Identities = 62/301 (20%), Positives = 116/301 (38%), Gaps = 52/301 (17%)
Query: 45 HEARKGNENQD--ESQTSASSCD----------ETEIQISNQEEAERQPLGHVTKTRRR- 91
HE + E +D ES A D E E I + E+ER+ + + RR
Sbjct: 413 HEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRR 472
Query: 92 ----CKTVRVDPDSQQNHSEIKISNPTE-------FQNHEKQESQDLRATAKVP------ 134
+++ + + ++ ++K N TE ++ EK+E++ L P
Sbjct: 473 IARDVNSIKKEIEEEKTEDKLK-DNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKK 531
Query: 135 ------SPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTDESSKPGKNKRTAITTPNFKKL 188
S D +E E + +SK SEG++ E G + +K+
Sbjct: 532 IKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKI 591
Query: 189 HEAHFKEMESIDQYIERKKKH------FEEHNSMNELKQPINKGGVRTPVPPRGRLSVAS 242
+EA K E D + + ++E + + P++KGG + + + S
Sbjct: 592 YEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDS 651
Query: 243 TPISQR---RSQGRSCGPASQSTL--GLKGSLKRSAISAAKTGVRFSAATKDNEHKRSLT 297
+R R + + P +STL + L ++A S K+ + + D+E + +L
Sbjct: 652 EKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS----DSCSSDSETEDALE 707
Query: 298 K 298
K
Sbjct: 708 K 708
>gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]
Length = 292
Score = 37.4 bits (85), Expect = 0.027
Identities = 40/181 (22%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 48 RKGNENQDESQTSASSCDETEIQISNQEEAERQPLGHVTKTRRRCKTVRVDPDSQQNHSE 107
R G+ E D + I+N ++ Q ++R+ K+ + Q+ S
Sbjct: 107 RWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSH 166
Query: 108 IKISNPTEFQNHEKQESQDLRATAKVPSPPDEHQEAENAVSSGNRDSKVPSEGKKSLYTD 167
K Q K+E+ D+ A + + +E +SG R K P + KK
Sbjct: 167 KK-------QKKSKKEATDITADSS-------SEFSEETGASGTRKGKQPHKRKKKSRKK 212
Query: 168 ESSKPGKNKRTAITTPNFKKLHEAHFKEMESID-QYIERKKKHFEEHNSM--NELKQPIN 224
KP T + + +E E D + +RKK+ + H S+ NE+++ N
Sbjct: 213 SLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTN 272
Query: 225 K 225
K
Sbjct: 273 K 273
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,005,364
Number of Sequences: 37866
Number of extensions: 802691
Number of successful extensions: 5507
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 256
Number of HSP's that attempted gapping in prelim test: 4870
Number of HSP's gapped (non-prelim): 865
length of query: 440
length of database: 18,247,518
effective HSP length: 105
effective length of query: 335
effective length of database: 14,271,588
effective search space: 4780981980
effective search space used: 4780981980
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.