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Search of human proteins with 171916095
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|171916095 SMEK homolog 2, suppressor of mek1 isoform 1 [Homo
sapiens]
(849 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|171916095 SMEK homolog 2, suppressor of mek1 isoform 1 [Homo ... 1690 0.0
gi|39930397 SMEK homolog 2, suppressor of mek1 isoform 2 [Homo s... 1456 0.0
gi|31657117 SMEK homolog 1, suppressor of mek1 [Homo sapiens] 1201 0.0
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 40 0.009
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 40 0.009
gi|145580615 KRI1 homolog [Homo sapiens] 39 0.020
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 37 0.059
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 37 0.059
gi|210032580 SET domain containing 1B [Homo sapiens] 37 0.059
gi|145309298 coiled-coil domain containing 16 [Homo sapiens] 37 0.077
gi|60685227 SECIS binding protein 2-like [Homo sapiens] 36 0.17
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 35 0.22
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 35 0.22
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 35 0.22
gi|83415174 hypothetical protein LOC400818 [Homo sapiens] 35 0.29
gi|118600967 shroom family member 4 [Homo sapiens] 35 0.38
gi|158534059 formin binding protein 4 [Homo sapiens] 35 0.38
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 35 0.38
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 35 0.38
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 35 0.38
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 34 0.50
gi|122937247 unc-13 homolog A [Homo sapiens] 34 0.50
gi|55770834 centromere protein F [Homo sapiens] 34 0.50
gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sa... 34 0.65
gi|209915570 amyloid beta A4 protein isoform e precursor [Homo s... 34 0.65
gi|55741677 SET domain containing 1A [Homo sapiens] 34 0.65
gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 K... 34 0.65
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 34 0.65
gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo ... 33 0.85
gi|38788260 bromodomain PHD finger transcription factor isoform ... 33 0.85
>gi|171916095 SMEK homolog 2, suppressor of mek1 isoform 1 [Homo
sapiens]
Length = 849
Score = 1690 bits (4376), Expect = 0.0
Identities = 849/849 (100%), Positives = 849/849 (100%)
Query: 1 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 60
MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT
Sbjct: 1 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 60
Query: 61 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 120
AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE
Sbjct: 61 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 120
Query: 121 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 180
RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ
Sbjct: 121 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 180
Query: 181 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 240
ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE
Sbjct: 181 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 240
Query: 241 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 300
FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV
Sbjct: 241 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 300
Query: 301 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 360
EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA
Sbjct: 301 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 360
Query: 361 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 420
KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI
Sbjct: 361 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 420
Query: 421 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 480
EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT
Sbjct: 421 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 480
Query: 481 NTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT 540
NTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT
Sbjct: 481 NTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT 540
Query: 541 AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL 600
AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL
Sbjct: 541 AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL 600
Query: 601 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 660
KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY
Sbjct: 601 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 660
Query: 661 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED 720
KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED
Sbjct: 661 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED 720
Query: 721 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 780
EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA
Sbjct: 721 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 780
Query: 781 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 840
SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS
Sbjct: 781 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 840
Query: 841 PRKRPRLGS 849
PRKRPRLGS
Sbjct: 841 PRKRPRLGS 849
>gi|39930397 SMEK homolog 2, suppressor of mek1 isoform 2 [Homo
sapiens]
Length = 764
Score = 1456 bits (3769), Expect = 0.0
Identities = 757/849 (89%), Positives = 760/849 (89%), Gaps = 85/849 (10%)
Query: 1 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 60
MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT
Sbjct: 1 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 60
Query: 61 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 120
AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE
Sbjct: 61 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 120
Query: 121 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 180
RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ
Sbjct: 121 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 180
Query: 181 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 240
ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE
Sbjct: 181 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 240
Query: 241 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 300
FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV
Sbjct: 241 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 300
Query: 301 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 360
EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA
Sbjct: 301 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 360
Query: 361 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 420
KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI
Sbjct: 361 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 420
Query: 421 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 480
EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT
Sbjct: 421 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 480
Query: 481 NTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT 540
NTSEDKCEK DNIVGSNKNNTICP +
Sbjct: 481 NTSEDKCEK--------------------------------DNIVGSNKNNTICPGALR- 507
Query: 541 AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL 600
+RR+ IGL
Sbjct: 508 ------------------------------FMRRI----------------------IGL 515
Query: 601 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 660
KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY
Sbjct: 516 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 575
Query: 661 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED 720
KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED
Sbjct: 576 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED 635
Query: 721 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 780
EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA
Sbjct: 636 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 695
Query: 781 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 840
SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS
Sbjct: 696 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 755
Query: 841 PRKRPRLGS 849
PRKRPRLGS
Sbjct: 756 PRKRPRLGS 764
>gi|31657117 SMEK homolog 1, suppressor of mek1 [Homo sapiens]
Length = 820
Score = 1201 bits (3107), Expect = 0.0
Identities = 612/860 (71%), Positives = 708/860 (82%), Gaps = 64/860 (7%)
Query: 1 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 60
M+DTRRRVKVYTLNEDRQWDDRGTGHVSS YVE LKGMSLLVRAESDGSLLLESKINPNT
Sbjct: 1 MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESDGSLLLESKINPNT 60
Query: 61 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 120
AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSV++TQDL+DESEEE
Sbjct: 61 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEE 120
Query: 121 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 180
RF++M +S ++LP+CEL++LEEIA+LV S L SP+RREKLALALENEGYIKKLL+LF
Sbjct: 121 RFDDM--SSPGLELPSCELSRLEEIAELVASSLPSPLRREKLALALENEGYIKKLLELFH 178
Query: 181 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 240
CE+LEN EGLHHLYEII+GI LN+ LFEVMFS+ECIMDV+GCLEYDPAL+QP++HRE
Sbjct: 179 VCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPALSQPRKHRE 238
Query: 241 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 300
FLTKTAKFKEVIPI+D EL+QKIHQTYRVQYIQD++LPTPSVFEEN LSTL SFIFFNKV
Sbjct: 239 FLTKTAKFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEENMLSTLHSFIFFNKV 298
Query: 301 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 360
EIV MLQEDEKFL+++FAQLTDEATD++KR+ELVNF KEFCAFSQTLQPQNRDAFFKTL+
Sbjct: 299 EIVGMLQEDEKFLTDLFAQLTDEATDEEKRQELVNFLKEFCAFSQTLQPQNRDAFFKTLS 358
Query: 361 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 420
+GILPALE+++GMDD QVRSAATDIFSYLVE++PSMVREFVMQEAQQ+DDDILLIN++I
Sbjct: 359 NMGILPALEVILGMDDTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDDDILLINLII 418
Query: 421 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 480
E MICDTDPELGGAVQLMGLLRTL+DPENMLAT NKTEK+EFL FFY HCMHVLTAPLL
Sbjct: 419 EHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLA 478
Query: 481 NTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT 540
NT+EDK KD ++QT
Sbjct: 479 NTTEDKPSKD----------------------------------------------DFQT 492
Query: 541 AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL 600
AQLLAL+LELLTFCVEHHTYHIKNYI+NKD+LRRVLVLM SKH FLALCALRF R+IIGL
Sbjct: 493 AQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGL 552
Query: 601 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 660
KDEFYNRYI K LFEPV+ A L+NG+RYNL+NSA+IE+FEFIRVEDIKSLTAH++EN++
Sbjct: 553 KDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYW 612
Query: 661 KALESIEYVQTFKGLKTKYEQEKDRQ-NQKLNSVPSILRSNRFRRDAKALEEDEEMWFNE 719
KALE ++YVQTFKGLK ++EQ+++RQ N KL+S+ SILR++R+RRDA+ LE++EEMWFN
Sbjct: 613 KALEDVDYVQTFKGLKLRFEQQRERQDNPKLDSMRSILRNHRYRRDARTLEDEEEMWFNT 672
Query: 720 DEE--EEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFS 777
DE+ E+G+AVV+P +K K +DD D KFME KK KESE+KE L K G +F
Sbjct: 673 DEDDMEDGEAVVSPSDKTKNDDDIMDPISKFMERKKLKESEEKEVLLKTNLSGRQSPSFK 732
Query: 778 HSASAANGTN--SKSVVAQIPPAT----------SNGSSSKTTNLPTSVTATKGSLVGLV 825
S S+ TN S+S +P + S GS K T+ ++T TKG LVGLV
Sbjct: 733 LSLSSGTKTNLTSQSSTTNLPGSPGSPGSPGSPGSPGSVPKNTSQTAAIT-TKGGLVGLV 791
Query: 826 DYPDDEEEDEEEESSPRKRP 845
DYPDD+E+D+E+E P
Sbjct: 792 DYPDDDEDDDEDEDKEDTLP 811
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 40.0 bits (92), Expect = 0.009
Identities = 42/166 (25%), Positives = 64/166 (38%), Gaps = 8/166 (4%)
Query: 676 KTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKP 735
+TK E EK + L ++ L + +A EE EE E EEEE A +PV+
Sbjct: 459 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEE--PEAEEEEVAAKKSPVKAT 516
Query: 736 KPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQI 795
PE + ++ E ++ +E ED+ + GG + S S A+
Sbjct: 517 APEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS-SEKEEGEQEEGETEAEA 575
Query: 796 PPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESSP 841
+ K + ATK LV D + E E+ SP
Sbjct: 576 EGEEAEAKEEKKVEEKSEEVATKEELVA-----DAKVEKPEKAKSP 616
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 40.0 bits (92), Expect = 0.009
Identities = 42/166 (25%), Positives = 64/166 (38%), Gaps = 8/166 (4%)
Query: 676 KTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKP 735
+TK E EK + L ++ L + +A EE EE E EEEE A +PV+
Sbjct: 83 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEE--PEAEEEEVAAKKSPVKAT 140
Query: 736 KPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQI 795
PE + ++ E ++ +E ED+ + GG + S S A+
Sbjct: 141 APEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS-SEKEEGEQEEGETEAEA 199
Query: 796 PPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESSP 841
+ K + ATK LV D + E E+ SP
Sbjct: 200 EGEEAEAKEEKKVEEKSEEVATKEELVA-----DAKVEKPEKAKSP 240
>gi|145580615 KRI1 homolog [Homo sapiens]
Length = 709
Score = 38.9 bits (89), Expect = 0.020
Identities = 40/141 (28%), Positives = 60/141 (42%), Gaps = 20/141 (14%)
Query: 661 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSV---PSILRSNRFRRDA---KALEEDEE 714
KA E +Y++ KG K + ++ L P + RF RD K EE+EE
Sbjct: 201 KAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEE 260
Query: 715 MWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKF 774
+E+E EE + V P + DD D E F+ KK ++ E K N F
Sbjct: 261 EEEDEEEMEEEEGVHGPPVQ-LAVDDSSDEGELFL--KKQEDFEQKYN-----------F 306
Query: 775 TFSHSASAANGTNSKSVVAQI 795
F SA+ T +S+ + +
Sbjct: 307 RFEEPDSASVKTYPRSIASSV 327
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 37.4 bits (85), Expect = 0.059
Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 34/178 (19%)
Query: 666 IEYVQTFKGLKTKYEQEKDRQNQKLNS-VPSILRSNRFRRDAKALEEDEEMWFNEDEEEE 724
+E+++ + + EK+ +N+ + S + S ++S F+ K L E+E E EEE
Sbjct: 295 VEHLELLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQEMEEEN 354
Query: 725 GKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSASAAN 784
++ + E+ + ED+ A ESE ++ K+ P F +HS N
Sbjct: 355 KESSSSSSEEEEGEDE-------------ASESETEKEADKK--PEAF---VNHS----N 392
Query: 785 GTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESSPR 842
+ S+ QIP N S+ + +S GL + P EE +E SS R
Sbjct: 393 SESKSSITEQIPAPAQNTFSASSARRFSS---------GLFNKP--EEPKDESPSSWR 439
>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform a [Homo sapiens]
Length = 982
Score = 37.4 bits (85), Expect = 0.059
Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 34/178 (19%)
Query: 666 IEYVQTFKGLKTKYEQEKDRQNQKLNS-VPSILRSNRFRRDAKALEEDEEMWFNEDEEEE 724
+E+++ + + EK+ +N+ + S + S ++S F+ K L E+E E EEE
Sbjct: 295 VEHLELLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQEMEEEN 354
Query: 725 GKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSASAAN 784
++ + E+ + ED+ A ESE ++ K+ P F +HS N
Sbjct: 355 KESSSSSSEEEEGEDE-------------ASESETEKEADKK--PEAF---VNHS----N 392
Query: 785 GTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESSPR 842
+ S+ QIP N S+ + +S GL + P EE +E SS R
Sbjct: 393 SESKSSITEQIPAPAQNTFSASSARRFSS---------GLFNKP--EEPKDESPSSWR 439
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 37.4 bits (85), Expect = 0.059
Identities = 34/142 (23%), Positives = 63/142 (44%), Gaps = 19/142 (13%)
Query: 703 RRDAKALE------EDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKE 756
RR A+ LE EDE+ +E++E + A E+ + +DD D+ + + E
Sbjct: 1021 RRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDS-----DDRDESE 1075
Query: 757 SEDKENLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTA 816
++D++ S ++ + S+V ATS+ SS+++ +S +
Sbjct: 1076 NDDEDTALSEAS--------EKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSES 1127
Query: 817 TKGSLVGLVDYPDDEEEDEEEE 838
+ S + EEE+EEEE
Sbjct: 1128 SPSSSEDEEEVVAREEEEEEEE 1149
>gi|145309298 coiled-coil domain containing 16 [Homo sapiens]
Length = 372
Score = 37.0 bits (84), Expect = 0.077
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 13/106 (12%)
Query: 746 EKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSS 805
EK E K AKE+ + +S + A A+ + K A + P +S+
Sbjct: 77 EKVAELKGAKEAS------QGSSASSAPHSVKRKAPDADDQDVKRAKATLVPQVQPSTSA 130
Query: 806 KTTNLPT------SVTATKGSLVGLV-DYPDDEEEDEEEESSPRKR 844
TTN T +K S + L+ DY D+EEE+EEEE ++
Sbjct: 131 WTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERK 176
>gi|60685227 SECIS binding protein 2-like [Homo sapiens]
Length = 1056
Score = 35.8 bits (81), Expect = 0.17
Identities = 49/239 (20%), Positives = 97/239 (40%), Gaps = 54/239 (22%)
Query: 631 LLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQK- 689
L+ +V+ +F + E + + + E KA +K + EQE+ + K
Sbjct: 741 LVPVSVVGIFNYFGAESLFNKLVELTEEARKA---------YKDMVAAMEQEQAEEALKN 791
Query: 690 LNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFM 749
+ VP + +R A A+ + P+ + E ++ N+ +
Sbjct: 792 VKKVPHHMGHSRNPSAASAISFCS-------------VISEPISEVN-EKEYETNWRNMV 837
Query: 750 ETKKAKESEDKEN--------------LPKRTSPGGFK----FTFSHSASAANGTNSKSV 791
ET E+ + E LP T P G + T S +++ + G ++ S
Sbjct: 838 ETSDGLEASENEKEVSCKHSTSEKPSKLPFDTPPIGKQPSLVATGSTTSATSAGKSTASD 897
Query: 792 VAQIPPATSNGSSSKTTN-----------LPTSVTATKGSLV-GLVDYPDDEEEDEEEE 838
++ P +S ++T L +S+T+T +LV G+++ +DE+E+EEE+
Sbjct: 898 KEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEDEEEEED 956
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 35.4 bits (80), Expect = 0.22
Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 6/69 (8%)
Query: 698 RSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKES 757
+ + +++ + EE EE E+EE+EGK EK K + + +K ET+K KE
Sbjct: 2 KKKKKKKETEETEETEET--EEEEEKEGKR----KEKRKEKRKEKEKKKKTKETEKRKEK 55
Query: 758 EDKENLPKR 766
E++E KR
Sbjct: 56 EEEEKKRKR 64
Score = 32.3 bits (72), Expect = 1.9
Identities = 22/91 (24%), Positives = 44/91 (48%), Gaps = 12/91 (13%)
Query: 676 KTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKP 735
K K +++K ++ +K + + +R K EE+ E E+EEEE E+
Sbjct: 38 KEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEERE----EEEEEE--------EEE 85
Query: 736 KPEDDFPDNYEKFMETKKAKESEDKENLPKR 766
K E++ + + + K+ ++ E++E KR
Sbjct: 86 KEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116
Score = 30.0 bits (66), Expect = 9.4
Identities = 19/78 (24%), Positives = 39/78 (50%), Gaps = 8/78 (10%)
Query: 676 KTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKP 735
K K E+EK R+ ++ + + + + EE+EE E+E+EEG+ ++
Sbjct: 53 KEKEEEEKKRKRKR--------KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104
Query: 736 KPEDDFPDNYEKFMETKK 753
+ E++ ++ +TKK
Sbjct: 105 RKEEEEEKKKKRRRKTKK 122
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 35.4 bits (80), Expect = 0.22
Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 28/170 (16%)
Query: 660 YKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNE 719
YK+L Y + K + + +Q++ +Q Q+ +P RS++ +D K E+ E
Sbjct: 479 YKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMP---RSSQEEKDEKEKEK-------E 528
Query: 720 DEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLP---KRTSPGGFKFTF 776
E+EE EKP+ E+D D ++ + +++++KE + ++T+ +
Sbjct: 529 AEKEE--------EKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKG 580
Query: 777 SHSASAANGTNSKSVV-----AQIPPATSNGSSSKTTNLPTSVTATKGSL 821
+ S AN NS+ + A++ N SS T TA KG L
Sbjct: 581 RITRSMANEANSEEAITPQQSAELASMELNESSRWTEE--EMETAKKGLL 628
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 35.4 bits (80), Expect = 0.22
Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 28/170 (16%)
Query: 660 YKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNE 719
YK+L Y + K + + +Q++ +Q Q+ +P RS++ +D K E+ E
Sbjct: 479 YKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMP---RSSQEEKDEKEKEK-------E 528
Query: 720 DEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLP---KRTSPGGFKFTF 776
E+EE EKP+ E+D D ++ + +++++KE + ++T+ +
Sbjct: 529 AEKEE--------EKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKG 580
Query: 777 SHSASAANGTNSKSVV-----AQIPPATSNGSSSKTTNLPTSVTATKGSL 821
+ S AN NS+ + A++ N SS T TA KG L
Sbjct: 581 RITRSMANEANSEEAITPQQSAELASMELNESSRWTEE--EMETAKKGLL 628
>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
Length = 942
Score = 35.0 bits (79), Expect = 0.29
Identities = 44/204 (21%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 657 ENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMW 716
E + L+ E ++ +K L E+E + +KL RS A ++ +
Sbjct: 351 EKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKS 410
Query: 717 FNEDEEE---EGKAVVAP-VEKPKPEDDFPDNYEKFMET----------KKAKESEDKEN 762
+D +E EG + V+K PE+D DN + +E ++ +++E+KE
Sbjct: 411 QGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEV 470
Query: 763 LPKRTSPGGFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLV 822
++ SH +N + K+ + T +T + +S + V
Sbjct: 471 PEDSLEECAITYSNSHGPYDSNQPHRKTKI------TFEEDKVDSTLIGSSSHVEREDAV 524
Query: 823 GLVDYPDDEEEDEEEESSPRKRPR 846
++ P++E +DEEEE PR
Sbjct: 525 HII--PENESDDEEEEEKGPVSPR 546
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 34.7 bits (78), Expect = 0.38
Identities = 43/211 (20%), Positives = 79/211 (37%), Gaps = 21/211 (9%)
Query: 660 YKALESIEYVQTFK-GLKTKYEQEKDRQNQKLNSVPSILRSNRFR--------RDAKALE 710
Y+A+ S++ + FK LK E + L S+P LRS F + +A
Sbjct: 1015 YRAISSLDLLGDFKHALKKSEETSVYEEGSSLASMPHPLRSRAFSESHISLAPQSTRAWG 1074
Query: 711 EDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPG 770
+ F++ +E + + A + P P N+EK+ + A++ + ++ K+
Sbjct: 1075 QHRRELFSKGDETQSDLLGARKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEE 1134
Query: 771 GFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSSKTTNL----------PTSVTATKGS 820
+ ++ ++PP + +S + L P S +GS
Sbjct: 1135 EEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLSFGHLEGS 1194
Query: 821 LVGLVDYPDDEEEDEEEESS--PRKRPRLGS 849
G P ++E S P R LGS
Sbjct: 1195 RQGSQSVPAEQESFALHSSDFLPPIRGHLGS 1225
>gi|158534059 formin binding protein 4 [Homo sapiens]
Length = 1017
Score = 34.7 bits (78), Expect = 0.38
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 725 GKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSASAAN 784
G+ + + P P P + E + E + +P + +P T + +AA
Sbjct: 10 GRRPILQLSPPGPRGSTPG---RDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAA 66
Query: 785 GTNSKS-----VVAQIPPATSNGSSSKTTNLPTSVTATKG-SLVGLVDYPDDEEEDEEEE 838
+S S V ++P N T PT+V AT G L+G DD++ D E+
Sbjct: 67 SDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEK 126
Query: 839 SSPRK 843
+ K
Sbjct: 127 LAQSK 131
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 34.7 bits (78), Expect = 0.38
Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 12/130 (9%)
Query: 721 EEEEGKAVVAPVEKPKPEDDFP---DNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFS 777
+EE G + +P P ++ D EK KK K+ E+KEN K+ S S
Sbjct: 1356 KEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMS--------S 1407
Query: 778 HSASAANGTNSKSVVAQIPPATSNG-SSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEE 836
+ KS + P + + SSSK+ V T GS + +D++ D+E
Sbjct: 1408 RKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQE 1467
Query: 837 EESSPRKRPR 846
S ++R R
Sbjct: 1468 TFSICKERMR 1477
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 34.7 bits (78), Expect = 0.38
Identities = 39/174 (22%), Positives = 71/174 (40%), Gaps = 18/174 (10%)
Query: 673 KGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPV 732
K + + E+EK+R+ +K R + K E+D E ++ E++
Sbjct: 393 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK----- 447
Query: 733 EKPKPEDDFPDNYEKFMETKKAKESEDK--ENLPKRTSPGGFKFTFSHSASAANGTNSKS 790
EK K +D EK E ++KE ++K ++ RT P + + +S+ +S
Sbjct: 448 EKEKEQDK-----EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRS 502
Query: 791 VVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESSPRKR 844
+ P TS K++ P+ + K D ++E D E R+R
Sbjct: 503 RSSSRSPRTSKTIKRKSSRSPSPRSRNK------KDKKREKERDHISERRERER 550
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 34.7 bits (78), Expect = 0.38
Identities = 39/174 (22%), Positives = 71/174 (40%), Gaps = 18/174 (10%)
Query: 673 KGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPV 732
K + + E+EK+R+ +K R + K E+D E ++ E++
Sbjct: 277 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK----- 331
Query: 733 EKPKPEDDFPDNYEKFMETKKAKESEDK--ENLPKRTSPGGFKFTFSHSASAANGTNSKS 790
EK K +D EK E ++KE ++K ++ RT P + + +S+ +S
Sbjct: 332 EKEKEQDK-----EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRS 386
Query: 791 VVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESSPRKR 844
+ P TS K++ P+ + K D ++E D E R+R
Sbjct: 387 RSSSRSPRTSKTIKRKSSRSPSPRSRNK------KDKKREKERDHISERRERER 434
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 34.3 bits (77), Expect = 0.50
Identities = 53/197 (26%), Positives = 84/197 (42%), Gaps = 36/197 (18%)
Query: 680 EQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEG-----KAVVAPVEK 734
E+E+D++ N R+ + + + EE+EE +DEEEEG K+ AP+ K
Sbjct: 247 EEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEE----DDEEEEGDDEGQKSREAPILK 302
Query: 735 PKPE--DDFPD-NYEKFMETKKAKESEDKENLPKRTSPGGFKFTFS----HSASAANGTN 787
E ++ P E+ M+ + S+++E L + G +FT S + A
Sbjct: 303 EFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLER-----GGRFTRSQEEARKSHLARQQQ 357
Query: 788 SKSVVAQIP-------PATSNGSSSKTTN-LPTSVT--ATKGSLVGLVDYPDDEEED--- 834
K + P +S G K+ + P +T K SLV L + EEE
Sbjct: 358 EKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPP 417
Query: 835 --EEEESSPRKRPRLGS 849
+E SSP P+L S
Sbjct: 418 LLTKEASSPPPHPQLHS 434
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 34.3 bits (77), Expect = 0.50
Identities = 40/173 (23%), Positives = 69/173 (39%), Gaps = 25/173 (14%)
Query: 671 TFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVA 730
+ +G + E+++D + +SV S R+ +D + LEED E + E+E E +
Sbjct: 374 SLQGSDMEDERDRDSYHSCHSSVSYHKDSPRWDQDEEELEEDLEDFLEEEELPEDEE--- 430
Query: 731 PVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSASAANGTNSKS 790
E + E++ PD+ + + + +E K+ F AA G K+
Sbjct: 431 --ELEEEEEEVPDDLGSYAQREDVAVAEPKD------------FKRISLPPAAPGKEDKA 476
Query: 791 VVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESSPRK 843
VA T +K P AT + P+ E +EE PR+
Sbjct: 477 PVA----PTEAPDMAKVAPKP----ATPDKVPAAEQIPEAEPPKDEESFRPRE 521
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 34.3 bits (77), Expect = 0.50
Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 18/169 (10%)
Query: 32 VEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCD 91
+E K M+ ++ + + + ++ +I N +Q V AE QE
Sbjct: 839 LESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFV---AETSQRISKLQEDTSAH 895
Query: 92 E--IWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELNKLEEIADLV 149
+ + E + ++ K+ +++ D + E+E+ +E+ +++HL++ EL L E L
Sbjct: 896 QNVVAETLSALENKEKELQLLNDKV-ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLE 954
Query: 150 TSVLSSPI---RREKLALALENEGYIKKL--------LQLFQACENLEN 187
+SS I +RE L EN G +K++ + L Q E+ N
Sbjct: 955 KKEMSSIISLNKREIEELTQEN-GTLKEINASLNQEKMNLIQKSESFAN 1002
>gi|41406057 amyloid beta A4 protein isoform c precursor [Homo
sapiens]
Length = 695
Score = 33.9 bits (76), Expect = 0.65
Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 8/140 (5%)
Query: 51 LLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGK---DPSV 107
L E N ++A ++ D+ + W A+ D A ++K E++ +V+ + D
Sbjct: 189 LAEESDNVDSADAEEDDSDVWWGGADT-DYADGSEDKVVEVAEEEEVAEVEEEEADDDED 247
Query: 108 EVTQDLIDESEEERFEEMPE-TSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALAL 166
+ D ++E EE +EE E T+ + T +EE+ + T+ S+P +K L
Sbjct: 248 DEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKY---L 304
Query: 167 ENEGYIKKLLQLFQACENLE 186
E G + +A E LE
Sbjct: 305 ETPGDENEHAHFQKAKERLE 324
>gi|209915570 amyloid beta A4 protein isoform e precursor [Homo
sapiens]
Length = 639
Score = 33.9 bits (76), Expect = 0.65
Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 8/140 (5%)
Query: 51 LLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGK---DPSV 107
L E N ++A ++ D+ + W A+ D A ++K E++ +V+ + D
Sbjct: 133 LAEESDNVDSADAEEDDSDVWWGGADT-DYADGSEDKVVEVAEEEEVAEVEEEEADDDED 191
Query: 108 EVTQDLIDESEEERFEEMPE-TSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALAL 166
+ D ++E EE +EE E T+ + T +EE+ + T+ S+P +K L
Sbjct: 192 DEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKY---L 248
Query: 167 ENEGYIKKLLQLFQACENLE 186
E G + +A E LE
Sbjct: 249 ETPGDENEHAHFQKAKERLE 268
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 33.9 bits (76), Expect = 0.65
Identities = 32/144 (22%), Positives = 59/144 (40%), Gaps = 23/144 (15%)
Query: 702 FRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKE 761
F D++ E +E +DEE++ + +++ D E TKK E D E
Sbjct: 959 FALDSEGEEASQESSSEKDEEDD-----------EEDEEDEDREEAVDTTKKETEVSDGE 1007
Query: 762 NLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSL 821
+ S K + + N + S S + ++S+ SSS +++ +S + +
Sbjct: 1008 D---EESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSS-- 1062
Query: 822 VGLVDYPDDEEEDEEEESSPRKRP 845
+DEEE+E + P P
Sbjct: 1063 -------EDEEEEERPAALPSASP 1079
>gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 2 [Homo sapiens]
Length = 686
Score = 33.9 bits (76), Expect = 0.65
Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 82 LSFQEKAGCDEIWEKICQVQGKDPS--VEVTQDLIDESE-EERFEEMPETSHLIDLPTCE 138
+S ++K G +E +E CQ + + P+ TQDL++E ER +M +T + ID T
Sbjct: 1 MSLRDKGGEEECFEYDCQDEERKPTHRQHDTQDLLEEVLCAERVGQMTKTYNDIDAVTRL 60
Query: 139 LNKLEEIADLVTSVLSSPIRREK 161
L + E +L + S +++ K
Sbjct: 61 LEEKERDLELAARIGQSLLKKNK 83
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 33.9 bits (76), Expect = 0.65
Identities = 33/135 (24%), Positives = 58/135 (42%), Gaps = 13/135 (9%)
Query: 680 EQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKPKPED 739
E E+D++ Q+ R+ R +D + + D E E E+E+GK + P +
Sbjct: 439 EHERDKERQRRKEEWERERAKRDEKDRQHRDRDRE---KEREKEKGKPKPRSPQPPSRQA 495
Query: 740 DFPDNYEKFM--ETKKAKESED--------KENLPKRTSPGGFKFTFSHSASAANGTNSK 789
+ P + K+A E +D K+ L SP + SAS+A+ +NS
Sbjct: 496 EPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSS 555
Query: 790 SVVAQIPPATSNGSS 804
++ + +GSS
Sbjct: 556 RSSSRSSSYSGSGSS 570
>gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo
sapiens]
Length = 3258
Score = 33.5 bits (75), Expect = 0.85
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 8/84 (9%)
Query: 39 SLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKA--GCDEIWEK 96
SL+ S+ +L E+ ++ +AYQ + V + Y L+L+ ++ G +WE
Sbjct: 2893 SLIAEFNSELKILKEA-VHSGSAYQGKTSISTVGTSTSAYRLSLATMSRSNTGTGTVWE- 2950
Query: 97 ICQVQGKDPSVEVTQDLIDESEEE 120
Q +PS + +QD + ++EE
Sbjct: 2951 ----QDSEPSQQASQDTLSRTDEE 2970
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 33.5 bits (75), Expect = 0.85
Identities = 42/202 (20%), Positives = 77/202 (38%), Gaps = 40/202 (19%)
Query: 664 ESIEYVQTFKG----LKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNE 719
E +E ++ KG +K+ E EKD+ + +S + NR + ++LE+D + +
Sbjct: 555 EILESIRAKKGDIDNVKSPEETEKDKNETENDSKDA--EKNREEFEDQSLEKDSDDKTPD 612
Query: 720 DEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHS 779
D+ E+GK+ E+P D ++ + + ++ + + SP G S
Sbjct: 613 DDPEQGKS-----EEPTEVGDKGNSVSANLGDNTTNATSEETSPSEGRSPVGCLSETPDS 667
Query: 780 ASAA--------------------NGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKG 819
++ A +N+ + I P N +SS N S +A
Sbjct: 668 SNMAEKKVASELPQDVPEEPNKTCESSNTSATTTSIQPNLENSNSSSELNSSQSESAKAA 727
Query: 820 SLVGLVDYPDDEEEDEEEESSP 841
DD E E E +P
Sbjct: 728 ---------DDPENGERESHTP 740
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,631,109
Number of Sequences: 37866
Number of extensions: 1462372
Number of successful extensions: 9937
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 151
Number of HSP's that attempted gapping in prelim test: 9084
Number of HSP's gapped (non-prelim): 845
length of query: 849
length of database: 18,247,518
effective HSP length: 111
effective length of query: 738
effective length of database: 14,044,392
effective search space: 10364761296
effective search space used: 10364761296
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.