Guide to the Human Genome
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Search of human proteins with 17149842

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo
sapiens]
         (142 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo sapi...   289   5e-79
gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens]   289   5e-79
gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens]   289   5e-79
gi|192448443 FK506 binding protein 10 [Homo sapiens]                  100   7e-22
gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]          99   9e-22
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]          99   9e-22
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]          99   9e-22
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]            99   9e-22
gi|206725547 FK506 binding protein 7 isoform b precursor [Homo s...    99   1e-21
gi|33469985 FK506 binding protein 9 [Homo sapiens]                     99   2e-21
gi|8923659 FK506 binding protein 14 [Homo sapiens]                     98   2e-21
gi|7706131 FK506 binding protein 11 isoform 1 precursor [Homo sa...    98   3e-21
gi|31317231 FK506 binding protein 7 isoform a precursor [Homo sa...    97   6e-21
gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]             97   6e-21
gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]              97   6e-21
gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]               93   8e-20
gi|4503729 FK506 binding protein 52 [Homo sapiens]                     92   2e-19
gi|219842220 FK506 binding protein 11 isoform 3 precursor [Homo ...    91   4e-19
gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo sa...    88   3e-18
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           61   4e-10
gi|219842217 FK506 binding protein 11 isoform 2 [Homo sapiens]         54   4e-08
gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens]          54   6e-08
gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens]          54   6e-08
gi|17149839 FK506 binding protein 1B, 12.6 kDa isoform b [Homo s...    53   7e-08
gi|52630440 FK506-binding protein 8 [Homo sapiens]                     40   5e-04
gi|83779010 SECIS binding protein 2 [Homo sapiens]                     29   1.1  
gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like ...    28   2.0  
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               28   2.0  
gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2...    28   2.6  
gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1...    28   2.6  

>gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo
           sapiens]
          Length = 142

 Score =  289 bits (740), Expect = 5e-79
 Identities = 142/142 (100%), Positives = 142/142 (100%)

Query: 1   MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60
           MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL
Sbjct: 1   MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60

Query: 61  EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120
           EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK
Sbjct: 61  EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120

Query: 121 IPGGATLVFEVELLKIERRTEL 142
           IPGGATLVFEVELLKIERRTEL
Sbjct: 121 IPGGATLVFEVELLKIERRTEL 142


>gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
          Length = 142

 Score =  289 bits (740), Expect = 5e-79
 Identities = 142/142 (100%), Positives = 142/142 (100%)

Query: 1   MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60
           MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL
Sbjct: 1   MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60

Query: 61  EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120
           EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK
Sbjct: 61  EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120

Query: 121 IPGGATLVFEVELLKIERRTEL 142
           IPGGATLVFEVELLKIERRTEL
Sbjct: 121 IPGGATLVFEVELLKIERRTEL 142


>gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
          Length = 142

 Score =  289 bits (740), Expect = 5e-79
 Identities = 142/142 (100%), Positives = 142/142 (100%)

Query: 1   MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60
           MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL
Sbjct: 1   MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60

Query: 61  EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120
           EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK
Sbjct: 61  EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120

Query: 121 IPGGATLVFEVELLKIERRTEL 142
           IPGGATLVFEVELLKIERRTEL
Sbjct: 121 IPGGATLVFEVELLKIERRTEL 142


>gi|192448443 FK506 binding protein 10 [Homo sapiens]
          Length = 582

 Score = 99.8 bits (247), Expect = 7e-22
 Identities = 49/106 (46%), Positives = 66/106 (62%)

Query: 31  LQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWD 90
           +Q+    R  HCP   + GD +  HY G L DGT FD+S  +   +   +G+G +IKG D
Sbjct: 156 VQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMD 215

Query: 91  QGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
           QGLLGMC GE+RK++IP  L YGE+G    IP  A+LVF V L+ +
Sbjct: 216 QGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDV 261



 Score = 93.2 bits (230), Expect = 6e-20
 Identities = 43/93 (46%), Positives = 56/93 (60%)

Query: 42  CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
           C  ++  GD +  HY G L DGT FDSS  +N  +   +G G +I G DQGL G C GE+
Sbjct: 279 CVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGER 338

Query: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
           R++ IP  L YGE G   KIPG A L+F V ++
Sbjct: 339 RRITIPPHLAYGENGTGDKIPGSAVLIFNVHVI 371



 Score = 92.4 bits (228), Expect = 1e-19
 Identities = 43/95 (45%), Positives = 59/95 (62%)

Query: 42  CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
           CP + + GD +  HY G  EDG +FDSS  +N      +G G++I G D+GL+GMC  E+
Sbjct: 55  CPREVQMGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNER 114

Query: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
           R+L++P  LGYG  G    IP  ATL F+V LL +
Sbjct: 115 RRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDV 149



 Score = 80.1 bits (196), Expect = 6e-16
 Identities = 42/96 (43%), Positives = 58/96 (60%), Gaps = 1/96 (1%)

Query: 42  CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
           C   ++ GD +  HY   L DGT+  +S     P   +LG  +VI+G D GL GMC GE+
Sbjct: 392 CNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGER 451

Query: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIE 137
           R+L++P  L +GE GA   +PG A L+FEVEL+  E
Sbjct: 452 RQLIVPPHLAHGESGA-RGVPGSAVLLFEVELVSRE 486


>gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]
          Length = 268

 Score = 99.4 bits (246), Expect = 9e-22
 Identities = 51/100 (51%), Positives = 65/100 (65%)

Query: 35  VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
           + KRV +       GD +++HY GKL +G +FDSS  +N+PFVFSLG GQVIK WD G+ 
Sbjct: 36  IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95

Query: 95  GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
            M +GE   L+   E  YG  G+ PKIP  ATL FE+ELL
Sbjct: 96  TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135


>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 99.4 bits (246), Expect = 9e-22
 Identities = 51/100 (51%), Positives = 65/100 (65%)

Query: 35  VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
           + KRV +       GD +++HY GKL +G +FDSS  +N+PFVFSLG GQVIK WD G+ 
Sbjct: 36  IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95

Query: 95  GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
            M +GE   L+   E  YG  G+ PKIP  ATL FE+ELL
Sbjct: 96  TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135



 Score = 30.8 bits (68), Expect = 0.39
 Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 10/98 (10%)

Query: 48  KGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQ---VIKGWDQGLLGMCEGEKRKL 104
           +G  + +H  G+   G  FD      +   F++G G+   +  G D+ L  M   E+  L
Sbjct: 164 EGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCIL 217

Query: 105 VIPSELGYGERGAPP-KIPGGATLVFEVELLKIERRTE 141
            +    G+GE G P   I   A L++EV L   E+  E
Sbjct: 218 YLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255


>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 99.4 bits (246), Expect = 9e-22
 Identities = 51/100 (51%), Positives = 65/100 (65%)

Query: 35  VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
           + KRV +       GD +++HY GKL +G +FDSS  +N+PFVFSLG GQVIK WD G+ 
Sbjct: 36  IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95

Query: 95  GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
            M +GE   L+   E  YG  G+ PKIP  ATL FE+ELL
Sbjct: 96  TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135



 Score = 30.8 bits (68), Expect = 0.39
 Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 10/98 (10%)

Query: 48  KGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQ---VIKGWDQGLLGMCEGEKRKL 104
           +G  + +H  G+   G  FD      +   F++G G+   +  G D+ L  M   E+  L
Sbjct: 164 EGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCIL 217

Query: 105 VIPSELGYGERGAPP-KIPGGATLVFEVELLKIERRTE 141
            +    G+GE G P   I   A L++EV L   E+  E
Sbjct: 218 YLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255


>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 99.4 bits (246), Expect = 9e-22
 Identities = 51/100 (51%), Positives = 65/100 (65%)

Query: 35  VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
           + KRV +       GD +++HY GKL +G +FDSS  +N+PFVFSLG GQVIK WD G+ 
Sbjct: 36  IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95

Query: 95  GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
            M +GE   L+   E  YG  G+ PKIP  ATL FE+ELL
Sbjct: 96  TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135



 Score = 30.8 bits (68), Expect = 0.39
 Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 10/98 (10%)

Query: 48  KGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQ---VIKGWDQGLLGMCEGEKRKL 104
           +G  + +H  G+   G  FD      +   F++G G+   +  G D+ L  M   E+  L
Sbjct: 164 EGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCIL 217

Query: 105 VIPSELGYGERGAPP-KIPGGATLVFEVELLKIERRTE 141
            +    G+GE G P   I   A L++EV L   E+  E
Sbjct: 218 YLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255


>gi|206725547 FK506 binding protein 7 isoform b precursor [Homo
           sapiens]
          Length = 221

 Score = 99.0 bits (245), Expect = 1e-21
 Identities = 54/116 (46%), Positives = 73/116 (62%), Gaps = 3/116 (2%)

Query: 26  EGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL-EDGTEFDSSLPQNQ--PFVFSLGT 82
           E   +++I V  R ++C   S+KGD+L+ HY G L +DG++F  S  QN+  P  F LG 
Sbjct: 30  ESTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGV 89

Query: 83  GQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIER 138
           GQVIKG D  +  MC GEKRK+VIP    YG+ G   KIP  ATL+FE+EL  + +
Sbjct: 90  GQVIKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYEGKIPPDATLIFEIELYAVTK 145


>gi|33469985 FK506 binding protein 9 [Homo sapiens]
          Length = 570

 Score = 98.6 bits (244), Expect = 2e-21
 Identities = 51/107 (47%), Positives = 69/107 (64%), Gaps = 3/107 (2%)

Query: 30  KLQIGVKKRV--DHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIK 87
           K  I ++ +V  ++C   S+ GD L  HY G L DGT FDSS  +N+ F   +G G VI 
Sbjct: 257 KDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIP 316

Query: 88  GWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
           G D+GLLG+C GEKR++V+P  LGYGE G    IPG A LVF++ ++
Sbjct: 317 GMDEGLLGVCIGEKRRIVVPPHLGYGEEGR-GNIPGSAVLVFDIHVI 362



 Score = 97.8 bits (242), Expect = 3e-21
 Identities = 46/95 (48%), Positives = 61/95 (64%)

Query: 42  CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
           C + S+KGD L  HY   L DGT  DS+    + +   LG+GQV+ G D GL  MC GEK
Sbjct: 382 CSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEK 441

Query: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
           R ++IP  LGYGE G   ++PG A LVF++ELL++
Sbjct: 442 RTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLEL 476



 Score = 87.8 bits (216), Expect = 3e-18
 Identities = 49/129 (37%), Positives = 66/129 (51%)

Query: 8   VLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFD 67
           +L +L       A   G     +LQI  +   D CP   R GD +  HY G   DG +FD
Sbjct: 13  LLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFD 72

Query: 68  SSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATL 127
           SS  ++  F   +G GQ+I G DQ L+GMC  E+R + IP +L YG  G    IP  + L
Sbjct: 73  SSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSGVIPPNSVL 132

Query: 128 VFEVELLKI 136
            F+V L+ I
Sbjct: 133 HFDVLLMDI 141



 Score = 85.5 bits (210), Expect = 1e-17
 Identities = 47/107 (43%), Positives = 62/107 (57%)

Query: 30  KLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGW 89
           ++QI    +   CP   +  D +  HY G   DGT FDSS  + + +   +G G +I G 
Sbjct: 147 QVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGM 206

Query: 90  DQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
           D+GLLGMC GEKR + IP  L YGE G    IPG A+LVF+V LL +
Sbjct: 207 DKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDL 253


>gi|8923659 FK506 binding protein 14 [Homo sapiens]
          Length = 211

 Score = 98.2 bits (243), Expect = 2e-21
 Identities = 57/129 (44%), Positives = 85/129 (65%), Gaps = 6/129 (4%)

Query: 11  VLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLE-DGTEFDSS 69
           VL++ ++++  A   E + K+++  K  +  C  K++ GD++ +HY G LE DG+ F S+
Sbjct: 9   VLTLFVTSLIGALIPEPEVKIEVLQKPFI--CHRKTKGGDLMLVHYEGYLEKDGSLFHST 66

Query: 70  LPQN--QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATL 127
              N  QP  F+LG  + +KGWDQGL GMC GEKRKL+IP  LGYG+ G   KIP  +TL
Sbjct: 67  HKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEG-KGKIPPESTL 125

Query: 128 VFEVELLKI 136
           +F ++LL+I
Sbjct: 126 IFNIDLLEI 134


>gi|7706131 FK506 binding protein 11 isoform 1 precursor [Homo
           sapiens]
          Length = 201

 Score = 97.8 bits (242), Expect = 3e-21
 Identities = 48/97 (49%), Positives = 63/97 (64%), Gaps = 1/97 (1%)

Query: 42  CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
           C   +  GD LH+HYTG L DG   D+SL ++ P V  LG  QVI G +Q LL MC GEK
Sbjct: 50  CAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRD-PLVIELGQKQVIPGLEQSLLDMCVGEK 108

Query: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIER 138
           R+ +IPS L YG+RG PP +P  A + ++VEL+ + R
Sbjct: 109 RRAIIPSHLAYGKRGFPPSVPADAVVQYDVELIALIR 145


>gi|31317231 FK506 binding protein 7 isoform a precursor [Homo
           sapiens]
          Length = 222

 Score = 96.7 bits (239), Expect = 6e-21
 Identities = 55/117 (47%), Positives = 74/117 (63%), Gaps = 4/117 (3%)

Query: 26  EGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL-EDGTEFDSSLPQNQ--PFVFSLGT 82
           E   +++I V  R ++C   S+KGD+L+ HY G L +DG++F  S  QN+  P  F LG 
Sbjct: 30  ESTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGV 89

Query: 83  GQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERG-APPKIPGGATLVFEVELLKIER 138
           GQVIKG D  +  MC GEKRK+VIP    YG+ G A  KIP  ATL+FE+EL  + +
Sbjct: 90  GQVIKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTK 146


>gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]
          Length = 108

 Score = 96.7 bits (239), Expect = 6e-21
 Identities = 46/91 (50%), Positives = 62/91 (68%)

Query: 47  RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVI 106
           ++G    +HYTG LEDG +FDSS  +N+PF F LG  +VI+GW++G+  M  G++ KL I
Sbjct: 18  KRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTI 77

Query: 107 PSELGYGERGAPPKIPGGATLVFEVELLKIE 137
             +  YG  G P  IP  ATLVF+VELLK+E
Sbjct: 78  SPDYAYGATGHPGIIPPHATLVFDVELLKLE 108


>gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]
          Length = 108

 Score = 96.7 bits (239), Expect = 6e-21
 Identities = 46/91 (50%), Positives = 62/91 (68%)

Query: 47  RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVI 106
           ++G    +HYTG LEDG +FDSS  +N+PF F LG  +VI+GW++G+  M  G++ KL I
Sbjct: 18  KRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTI 77

Query: 107 PSELGYGERGAPPKIPGGATLVFEVELLKIE 137
             +  YG  G P  IP  ATLVF+VELLK+E
Sbjct: 78  SPDYAYGATGHPGIIPPHATLVFDVELLKLE 108


>gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]
          Length = 224

 Score = 92.8 bits (229), Expect = 8e-20
 Identities = 53/120 (44%), Positives = 72/120 (60%), Gaps = 9/120 (7%)

Query: 26  EGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQN-------QPFVF 78
           EG  K    V K+ D      +KGDV+H  YTG L+DGT FD+++  +       +P  F
Sbjct: 106 EGPPKYTKSVLKKGDKTNFP-KKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSF 164

Query: 79  SLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAP-PKIPGGATLVFEVELLKIE 137
            +G G+VI+GWD+ LL M +GEK +L I  E  YG++G P  KIP  A L FEVEL+ I+
Sbjct: 165 KVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224


>gi|4503729 FK506 binding protein 52 [Homo sapiens]
          Length = 459

 Score = 91.7 bits (226), Expect = 2e-19
 Identities = 46/89 (51%), Positives = 56/89 (62%)

Query: 49  GDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS 108
           GD + +HYTG L DGT+FDSSL +   F F LG G+VIK WD  +  M  GE   +    
Sbjct: 50  GDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKP 109

Query: 109 ELGYGERGAPPKIPGGATLVFEVELLKIE 137
           E  YG  G+PPKIP  ATLVFEVEL + +
Sbjct: 110 EYAYGSAGSPPKIPPNATLVFEVELFEFK 138


>gi|219842220 FK506 binding protein 11 isoform 3 precursor [Homo
           sapiens]
          Length = 146

 Score = 90.5 bits (223), Expect = 4e-19
 Identities = 44/82 (53%), Positives = 54/82 (65%), Gaps = 1/82 (1%)

Query: 42  CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
           C   +  GD LH+HYTG L DG   D+SL ++ P V  LG  QVI G +Q LL MC GEK
Sbjct: 50  CAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRD-PLVIELGQKQVIPGLEQSLLDMCVGEK 108

Query: 102 RKLVIPSELGYGERGAPPKIPG 123
           R+ +IPS L YG+RG PP +PG
Sbjct: 109 RRAIIPSHLAYGKRGFPPSVPG 130


>gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo
           sapiens]
          Length = 108

 Score = 87.8 bits (216), Expect = 3e-18
 Identities = 41/91 (45%), Positives = 60/91 (65%)

Query: 47  RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVI 106
           +KG    +HYTG L++G +FDSS  +N+PF F +G  +VIKG+++G   M  G++ KL  
Sbjct: 18  KKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTC 77

Query: 107 PSELGYGERGAPPKIPGGATLVFEVELLKIE 137
             ++ YG  G P  IP  ATL+F+VELL +E
Sbjct: 78  TPDVAYGATGHPGVIPPNATLIFDVELLNLE 108


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 60.8 bits (146), Expect = 4e-10
 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 5/94 (5%)

Query: 49  GDVLHMHYTGKLED----GTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKL 104
           GD L + YTG L      G  FDS+  +++     LG+G+VIKGW+ G+LGM +G KR L
Sbjct: 197 GDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGKRLL 256

Query: 105 VIPSELGYGERGAPPKIPG-GATLVFEVELLKIE 137
           ++P     G  G         + LVFEVE+ +++
Sbjct: 257 IVPPACAVGSEGVIGWTQATDSILVFEVEVRRVK 290


>gi|219842217 FK506 binding protein 11 isoform 2 [Homo sapiens]
          Length = 99

 Score = 53.9 bits (128), Expect = 4e-08
 Identities = 22/43 (51%), Positives = 31/43 (72%)

Query: 96  MCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIER 138
           MC GEKR+ +IPS L YG+RG PP +P  A + ++VEL+ + R
Sbjct: 1   MCVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVELIALIR 43


>gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens]
          Length = 322

 Score = 53.5 bits (127), Expect = 6e-08
 Identities = 37/114 (32%), Positives = 54/114 (47%), Gaps = 7/114 (6%)

Query: 28  KRKLQIGVKKRVDHCPIKSRKGDVLH------MHYTGKLED-GTEFDSSLPQNQPFVFSL 80
           +R L I   + V    I+   GD++       + Y+G LE     FDS+  +  P +  L
Sbjct: 22  QRMLDISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKL 81

Query: 81  GTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
           G    + G + GLL M  GE  + +      YG  G PP IP   T++FE+ELL
Sbjct: 82  GEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELL 135


>gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens]
          Length = 327

 Score = 53.5 bits (127), Expect = 6e-08
 Identities = 37/114 (32%), Positives = 54/114 (47%), Gaps = 7/114 (6%)

Query: 28  KRKLQIGVKKRVDHCPIKSRKGDVLH------MHYTGKLED-GTEFDSSLPQNQPFVFSL 80
           +R L I   + V    I+   GD++       + Y+G LE     FDS+  +  P +  L
Sbjct: 27  QRMLDISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKL 86

Query: 81  GTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
           G    + G + GLL M  GE  + +      YG  G PP IP   T++FE+ELL
Sbjct: 87  GEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELL 140


>gi|17149839 FK506 binding protein 1B, 12.6 kDa isoform b [Homo
          sapiens]
          Length = 80

 Score = 53.1 bits (126), Expect = 7e-08
 Identities = 22/46 (47%), Positives = 34/46 (73%)

Query: 47 RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQG 92
          +KG    +HYTG L++G +FDSS  +N+PF F +G  +VIKG+++G
Sbjct: 18 KKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEG 63


>gi|52630440 FK506-binding protein 8 [Homo sapiens]
          Length = 413

 Score = 40.4 bits (93), Expect = 5e-04
 Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 7/88 (7%)

Query: 48  KGDVLHMHYTGKLEDGTEFDSSLPQNQP-FVFSLGTGQVIKGWDQGLLGMCEGEKRKLVI 106
           KG V+ +H    LE+GT       Q +P  VF+LG   VI+  D  +  M  GE   +  
Sbjct: 119 KGQVVTVHLQTSLENGTRV-----QEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTA 173

Query: 107 PSELGYGERGA-PPKIPGGATLVFEVEL 133
            S+  YG +G+  P IP  A L  EV L
Sbjct: 174 DSKYCYGPQGSRSPYIPPHAALCLEVTL 201


>gi|83779010 SECIS binding protein 2 [Homo sapiens]
          Length = 854

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 7/63 (11%)

Query: 25  AEGKRKLQIGVKKRVDHCPIKSRKGDVLH-----MHYTGKLEDG--TEFDSSLPQNQPFV 77
           A+ KR+L +G+++ + H  +K  K  ++      +   G L+D   T  D +  QN PFV
Sbjct: 667 AKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFV 726

Query: 78  FSL 80
           F+L
Sbjct: 727 FAL 729


>gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like
           [Homo sapiens]
          Length = 484

 Score = 28.5 bits (62), Expect = 2.0
 Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 20/129 (15%)

Query: 24  GAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTG 83
           G E KR+LQ+  + R D    KS+         TGK ED    +  +P          +G
Sbjct: 323 GEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPV---------SG 373

Query: 84  QVIK---GWDQGLLGMC--------EGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVE 132
           Q  K    WD G LG          E E     +P+ +   +       PG + LV ++ 
Sbjct: 374 QEAKEPESWDGGRLGAVGRARSREEENEHHGPSMPALIAPEDSPHCDLFPGASYLVTQIP 433

Query: 133 LLKIERRTE 141
             + E R E
Sbjct: 434 GTQTESRAE 442


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 28.5 bits (62), Expect = 2.0
 Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 6/69 (8%)

Query: 45  KSRKGDVLHMHYT-----GKLEDGTEFDSSLPQNQPFVFSLGTGQVIK-GWDQGLLGMCE 98
           ++R GD +   Y      G  EDG E+D   P +   +  +G  + +K   +Q  +G  E
Sbjct: 404 RNRPGDKMRDRYNLNLLPGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDE 463

Query: 99  GEKRKLVIP 107
             + ++ IP
Sbjct: 464 SNEIEMTIP 472


>gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2
           [Homo sapiens]
          Length = 2083

 Score = 28.1 bits (61), Expect = 2.6
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 5/71 (7%)

Query: 20  ATATGAEGKRKLQIGVKKR---VDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPF 76
           AT TG+ G  K +  V+++   +D   I  R   V   H++   E G E   +L + QP 
Sbjct: 735 ATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRV--RHFSQSEETGNEVFGALNEEQPL 792

Query: 77  VFSLGTGQVIK 87
             S  T  +++
Sbjct: 793 PRSSSTSDILE 803


>gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1
           [Homo sapiens]
          Length = 2036

 Score = 28.1 bits (61), Expect = 2.6
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 5/71 (7%)

Query: 20  ATATGAEGKRKLQIGVKKR---VDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPF 76
           AT TG+ G  K +  V+++   +D   I  R   V   H++   E G E   +L + QP 
Sbjct: 735 ATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRV--RHFSQSEETGNEVFGALNEEQPL 792

Query: 77  VFSLGTGQVIK 87
             S  T  +++
Sbjct: 793 PRSSSTSDILE 803


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.139    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,685,849
Number of Sequences: 37866
Number of extensions: 255093
Number of successful extensions: 503
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 450
Number of HSP's gapped (non-prelim): 53
length of query: 142
length of database: 18,247,518
effective HSP length: 92
effective length of query: 50
effective length of database: 14,763,846
effective search space: 738192300
effective search space used: 738192300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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