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Search of human proteins with 170932518
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170932518 paxillin isoform 3 [Homo sapiens]
(424 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170932518 paxillin isoform 3 [Homo sapiens] 905 0.0
gi|170932516 paxillin isoform 2 [Homo sapiens] 905 0.0
gi|170932514 paxillin isoform 1 [Homo sapiens] 888 0.0
gi|221316659 leupaxin isoform 1 [Homo sapiens] 444 e-125
gi|4758670 leupaxin isoform 2 [Homo sapiens] 444 e-125
gi|109638745 transforming growth factor beta 1 induced transcrip... 419 e-117
gi|21361591 transforming growth factor beta 1 induced transcript... 419 e-117
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 161 9e-40
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 161 9e-40
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 149 6e-36
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 147 1e-35
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 147 1e-35
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 145 9e-35
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 145 9e-35
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 145 9e-35
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 145 9e-35
gi|194272207 actin binding LIM protein family, member 2 isoform ... 139 5e-33
gi|153792514 actin binding LIM protein family, member 2 isoform ... 139 5e-33
gi|194272204 actin binding LIM protein family, member 2 isoform ... 139 5e-33
gi|194272202 actin binding LIM protein family, member 2 isoform ... 139 5e-33
gi|194272200 actin binding LIM protein family, member 2 isoform ... 139 5e-33
gi|194272198 actin binding LIM protein family, member 2 isoform ... 139 5e-33
gi|194272196 actin binding LIM protein family, member 2 isoform ... 139 5e-33
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 137 2e-32
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 137 2e-32
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 137 2e-32
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 137 2e-32
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 131 1e-30
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 131 1e-30
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 124 2e-28
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 905 bits (2340), Expect = 0.0
Identities = 424/424 (100%), Positives = 424/424 (100%)
Query: 1 MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 60
MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK
Sbjct: 1 MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 60
Query: 61 AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 120
AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ
Sbjct: 61 AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 120
Query: 121 QTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 180
QTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNK
Sbjct: 121 QTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 180
Query: 181 LGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK 240
LGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK
Sbjct: 181 LGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK 240
Query: 241 DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300
DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD
Sbjct: 241 DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300
Query: 301 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360
YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY
Sbjct: 301 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360
Query: 361 HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 420
HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL
Sbjct: 361 HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 420
Query: 421 KLFC 424
KLFC
Sbjct: 421 KLFC 424
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 905 bits (2340), Expect = 0.0
Identities = 424/424 (100%), Positives = 424/424 (100%)
Query: 1 MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 60
MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK
Sbjct: 134 MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 193
Query: 61 AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 120
AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ
Sbjct: 194 AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 253
Query: 121 QTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 180
QTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNK
Sbjct: 254 QTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 313
Query: 181 LGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK 240
LGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK
Sbjct: 314 LGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK 373
Query: 241 DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300
DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD
Sbjct: 374 DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 433
Query: 301 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360
YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY
Sbjct: 434 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 493
Query: 361 HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 420
HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL
Sbjct: 494 HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 553
Query: 421 KLFC 424
KLFC
Sbjct: 554 KLFC 557
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 888 bits (2295), Expect = 0.0
Identities = 424/458 (92%), Positives = 424/458 (92%), Gaps = 34/458 (7%)
Query: 1 MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 60
MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK
Sbjct: 134 MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 193
Query: 61 AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 120
AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ
Sbjct: 194 AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 253
Query: 121 QTRISASSATRELDELMASLSDFK----------------------------------FM 146
QTRISASSATRELDELMASLSDFK FM
Sbjct: 254 QTRISASSATRELDELMASLSDFKIQGLEQRADGERCWAAGWPRDGGRSSPGGQDEGGFM 313
Query: 147 AQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAM 206
AQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAM
Sbjct: 314 AQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAM 373
Query: 207 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALD 266
GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALD
Sbjct: 374 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALD 433
Query: 267 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNT 326
RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNT
Sbjct: 434 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNT 493
Query: 327 LWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKK 386
LWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKK
Sbjct: 494 LWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKK 553
Query: 387 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC 424
FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC
Sbjct: 554 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC 591
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 444 bits (1141), Expect = e-125
Identities = 203/335 (60%), Positives = 245/335 (73%), Gaps = 12/335 (3%)
Query: 97 SPVPA---ITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGS 153
SP+PA T N E++ ++ S +SA +LDELMA L++ Q K
Sbjct: 59 SPLPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEM----QAKVAV 114
Query: 154 SSPPGGPPKPGSQ-----LDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGK 208
+ G P Q LDSMLG L+ +L LG+ATV KG C +C+KPIAG+V+ A+G+
Sbjct: 115 RADAGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQ 174
Query: 209 TWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRT 268
+WHPEHFVCTHC+EEIGS FFER G YC DYH LFSPRC YC PILDKV+TA+++T
Sbjct: 175 SWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQT 234
Query: 269 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLW 328
WHPEHFFC+ CG FG EGFHEKD K YCRKD+ MF+PKCGGC R +LENY+SA++T+W
Sbjct: 235 WHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVW 294
Query: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388
HPECFVC +CFT F GSFFE DG+P+CE+HYH RRG+LC GC +PITGRCI+AM KFH
Sbjct: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
Query: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
PEHFVCAFCL QL+KG F+EQNDK YCQ CF KLF
Sbjct: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 444 bits (1141), Expect = e-125
Identities = 203/335 (60%), Positives = 245/335 (73%), Gaps = 12/335 (3%)
Query: 97 SPVPA---ITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGS 153
SP+PA T N E++ ++ S +SA +LDELMA L++ Q K
Sbjct: 54 SPLPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEM----QAKVAV 109
Query: 154 SSPPGGPPKPGSQ-----LDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGK 208
+ G P Q LDSMLG L+ +L LG+ATV KG C +C+KPIAG+V+ A+G+
Sbjct: 110 RADAGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQ 169
Query: 209 TWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRT 268
+WHPEHFVCTHC+EEIGS FFER G YC DYH LFSPRC YC PILDKV+TA+++T
Sbjct: 170 SWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQT 229
Query: 269 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLW 328
WHPEHFFC+ CG FG EGFHEKD K YCRKD+ MF+PKCGGC R +LENY+SA++T+W
Sbjct: 230 WHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVW 289
Query: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388
HPECFVC +CFT F GSFFE DG+P+CE+HYH RRG+LC GC +PITGRCI+AM KFH
Sbjct: 290 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 349
Query: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
PEHFVCAFCL QL+KG F+EQNDK YCQ CF KLF
Sbjct: 350 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 419 bits (1076), Expect = e-117
Identities = 208/428 (48%), Positives = 265/428 (61%), Gaps = 32/428 (7%)
Query: 26 PPGF---PADEANSSPPLPGALSPLYGV---PETNSPLGGKAGPLTKEKPKRNGG----- 74
PP + P + S G LY P + P A P + G
Sbjct: 35 PPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSSSSGVLGTGLCELD 94
Query: 75 RGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQQT-----RISASSA 129
R L+++ + ++ DE+ S PS A + + S ++ S + SA+SA
Sbjct: 95 RLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPSLPSSPSPGLPKASATSA 154
Query: 130 TRELDELMASLSDFKFM----AQGKT----------GSSSPPGGPPKPGSQLDSMLGSLQ 175
T ELD LMASLSDF+ A G T GS SPP P LD+MLG LQ
Sbjct: 155 TLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPP--EPTGKGSLDTMLGLLQ 212
Query: 176 SDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQ 235
SDL++ GV T AKG+CG+C KPIAGQVVTA+G+ WHPEHFVC C +G +FFE+DG
Sbjct: 213 SDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGA 272
Query: 236 PYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKA 295
P+C + Y FSPRC +CN PI K+VTAL WHPEHF C CG FG EGFHE++G+
Sbjct: 273 PFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRP 332
Query: 296 YCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPY 355
YCR+D+ +FAP+C GC IL+NYISAL+ LWHP+CFVCRECF PF GSFFEH+G+P
Sbjct: 333 YCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPL 392
Query: 356 CEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYC 415
CE H+H RRGSLC+ C P+TGRC++A+ ++FHP+HF C FCL+ L KG+F+E+ KPYC
Sbjct: 393 CENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 452
Query: 416 QNCFLKLF 423
Q CFLKLF
Sbjct: 453 QPCFLKLF 460
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 419 bits (1076), Expect = e-117
Identities = 208/428 (48%), Positives = 265/428 (61%), Gaps = 32/428 (7%)
Query: 26 PPGF---PADEANSSPPLPGALSPLYGV---PETNSPLGGKAGPLTKEKPKRNGG----- 74
PP + P + S G LY P + P A P + G
Sbjct: 18 PPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSSSSGVLGTGLCELD 77
Query: 75 RGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQQT-----RISASSA 129
R L+++ + ++ DE+ S PS A + + S ++ S + SA+SA
Sbjct: 78 RLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPSLPSSPSPGLPKASATSA 137
Query: 130 TRELDELMASLSDFKFM----AQGKT----------GSSSPPGGPPKPGSQLDSMLGSLQ 175
T ELD LMASLSDF+ A G T GS SPP P LD+MLG LQ
Sbjct: 138 TLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPP--EPTGKGSLDTMLGLLQ 195
Query: 176 SDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQ 235
SDL++ GV T AKG+CG+C KPIAGQVVTA+G+ WHPEHFVC C +G +FFE+DG
Sbjct: 196 SDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGA 255
Query: 236 PYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKA 295
P+C + Y FSPRC +CN PI K+VTAL WHPEHF C CG FG EGFHE++G+
Sbjct: 256 PFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRP 315
Query: 296 YCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPY 355
YCR+D+ +FAP+C GC IL+NYISAL+ LWHP+CFVCRECF PF GSFFEH+G+P
Sbjct: 316 YCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPL 375
Query: 356 CEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYC 415
CE H+H RRGSLC+ C P+TGRC++A+ ++FHP+HF C FCL+ L KG+F+E+ KPYC
Sbjct: 376 CENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 435
Query: 416 QNCFLKLF 423
Q CFLKLF
Sbjct: 436 QPCFLKLF 443
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 161 bits (408), Expect = 9e-40
Identities = 87/278 (31%), Positives = 125/278 (44%), Gaps = 13/278 (4%)
Query: 96 PSPVPAITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSS 155
PSPVP T + +P + ++ S E ++D F + G S+
Sbjct: 337 PSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKST 396
Query: 156 --------PPGGPP--KPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTA 205
P GGP G Q+ + + A+ +CG C I G + A
Sbjct: 397 TSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAERFP-ASSRTPLCGHCNNVIRGPFLVA 455
Query: 206 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTAL 265
MG++WHPE F C +C+ + F E YCE+ Y F+P C CN I+ +V+ AL
Sbjct: 456 MGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHAL 515
Query: 266 DRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISA 323
+TWH F CA C FG FH +DG+ YC KDY ++F+ KC GC + + +I A
Sbjct: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
Query: 324 LNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 361
L WH CF+C C F+ +P C+ H H
Sbjct: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613
Score = 131 bits (330), Expect = 1e-30
Identities = 62/172 (36%), Positives = 81/172 (47%), Gaps = 2/172 (1%)
Query: 247 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306
+P C +CN I + A+ R+WHPE F CA C F E+ YC + Y FA
Sbjct: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P C C I+ + AL WH CFVC C PF N F DG+PYCE Y +
Sbjct: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557
Query: 367 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416
C GC P+ + I A+ +H F+CA C L F + D+P C+
Sbjct: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
Score = 85.1 bits (209), Expect = 1e-16
Identities = 39/117 (33%), Positives = 55/117 (47%)
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P CG C I ++ A+ WHPE F C C T + F E YCE Y +
Sbjct: 439 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
LC+ C I G + A+ + +H FVCA C K F ++ +PYC+ ++ LF
Sbjct: 499 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555
Score = 53.9 bits (128), Expect = 3e-07
Identities = 22/60 (36%), Positives = 31/60 (51%)
Query: 364 RGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
R LC C I G + AM + +HPE F CA+C L F E+ + YC+ C+ + F
Sbjct: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496
Score = 42.7 bits (99), Expect = 6e-04
Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 191 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
C C P+ + + A+G TWH F+C C + + F+ + +P C+K H +
Sbjct: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 615
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 161 bits (408), Expect = 9e-40
Identities = 87/278 (31%), Positives = 125/278 (44%), Gaps = 13/278 (4%)
Query: 96 PSPVPAITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSS 155
PSPVP T + +P + ++ S E ++D F + G S+
Sbjct: 447 PSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKST 506
Query: 156 --------PPGGPP--KPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTA 205
P GGP G Q+ + + A+ +CG C I G + A
Sbjct: 507 TSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAERFP-ASSRTPLCGHCNNVIRGPFLVA 565
Query: 206 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTAL 265
MG++WHPE F C +C+ + F E YCE+ Y F+P C CN I+ +V+ AL
Sbjct: 566 MGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHAL 625
Query: 266 DRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISA 323
+TWH F CA C FG FH +DG+ YC KDY ++F+ KC GC + + +I A
Sbjct: 626 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 685
Query: 324 LNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 361
L WH CF+C C F+ +P C+ H H
Sbjct: 686 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 723
Score = 131 bits (330), Expect = 1e-30
Identities = 62/172 (36%), Positives = 81/172 (47%), Gaps = 2/172 (1%)
Query: 247 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306
+P C +CN I + A+ R+WHPE F CA C F E+ YC + Y FA
Sbjct: 548 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 607
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P C C I+ + AL WH CFVC C PF N F DG+PYCE Y +
Sbjct: 608 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 667
Query: 367 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416
C GC P+ + I A+ +H F+CA C L F + D+P C+
Sbjct: 668 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719
Score = 85.1 bits (209), Expect = 1e-16
Identities = 39/117 (33%), Positives = 55/117 (47%)
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P CG C I ++ A+ WHPE F C C T + F E YCE Y +
Sbjct: 549 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 608
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
LC+ C I G + A+ + +H FVCA C K F ++ +PYC+ ++ LF
Sbjct: 609 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 665
Score = 53.9 bits (128), Expect = 3e-07
Identities = 22/60 (36%), Positives = 31/60 (51%)
Query: 364 RGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
R LC C I G + AM + +HPE F CA+C L F E+ + YC+ C+ + F
Sbjct: 547 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 606
Score = 42.7 bits (99), Expect = 6e-04
Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 191 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
C C P+ + + A+G TWH F+C C + + F+ + +P C+K H +
Sbjct: 669 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 725
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 149 bits (375), Expect = 6e-36
Identities = 80/238 (33%), Positives = 117/238 (49%), Gaps = 9/238 (3%)
Query: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 249
C C + I G+V+ AM +WHPE F C CQE + F + G+ C + HN R
Sbjct: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARG 129
Query: 250 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 304
C C+ I ++ + + +HP+HF CA CG + E G+ YC + M
Sbjct: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKM 188
Query: 305 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
P CG C R I ++A+ WH E FVC +C PF+ +E G YCE HY++
Sbjct: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
Query: 365 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 421
G +C C + I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
Score = 138 bits (348), Expect = 8e-33
Identities = 79/246 (32%), Positives = 121/246 (49%), Gaps = 10/246 (4%)
Query: 186 VAKGVCGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 243
+A C CK A ++V + G+ +H + FVC C ++ F+E +G+ YCE D+
Sbjct: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
Query: 244 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 303
LF+P C+ C I+ +V+ A++ +WHPE F C C GF + G+ CR +
Sbjct: 65 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 124
Query: 304 MFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEV 358
A C C I E + N +HP+ F C C + E G+ YC +
Sbjct: 125 EKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKE-LTADARELKGELYC-L 182
Query: 359 HYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 417
H++ G +C C++PI GR + AM K++H EHFVCA C K E+ YC+
Sbjct: 183 PCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCET 242
Query: 418 CFLKLF 423
+ +LF
Sbjct: 243 HYNQLF 248
Score = 114 bits (285), Expect = 2e-25
Identities = 60/178 (33%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 186 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
+ K +C C I Q + +HP+HF C +C +E+ + + E G+ YC + +
Sbjct: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKM 188
Query: 246 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 305
P C C PI +VV A+ + WH EHF CA+C F +E+ G AYC Y +F
Sbjct: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
Query: 306 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 362
C C R I + +SALN W CF C C T + F E D +P C+ Y +
Sbjct: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
Score = 105 bits (263), Expect = 6e-23
Identities = 52/124 (41%), Positives = 70/124 (56%), Gaps = 6/124 (4%)
Query: 179 NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 238
+K+GV +CGAC++PI G+VV AMGK WH EHFVC C++ +ER G YC
Sbjct: 186 DKMGVP-----ICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
Query: 239 EKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG-FHEKDGKAYC 297
E Y+ LF C++CN I VV+AL++ W F C+ C + F E D K C
Sbjct: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
Query: 298 RKDY 301
+K Y
Sbjct: 301 KKCY 304
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 147 bits (372), Expect = 1e-35
Identities = 71/172 (41%), Positives = 90/172 (52%), Gaps = 2/172 (1%)
Query: 247 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306
+P C +CN I + AL ++WHPE F CA C GF E+ G YC Y FA
Sbjct: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P+CG C R IL ISAL WH CFVC C P N F DG+PYCE Y+ G+
Sbjct: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
Query: 367 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416
+C GC+ PI + A+ +H FVC+ C + L TF + DKP C+
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
Score = 146 bits (369), Expect = 3e-35
Identities = 66/174 (37%), Positives = 88/174 (50%), Gaps = 2/174 (1%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
+C C + I G + A+GK+WHPE F C HC+ + F E G YCE Y F+P
Sbjct: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 309
C C IL +V++AL +TWH F C CG FH +DG+ YC DY+ +F C
Sbjct: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
Query: 310 GGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 361
GC I + ++ AL WH CFVC C +FF +P C+ H H
Sbjct: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAH 483
Score = 82.4 bits (202), Expect = 7e-16
Identities = 39/117 (33%), Positives = 55/117 (47%)
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P C C + I ++ AL WHPE F C C F E G YCE+ Y +
Sbjct: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
C CQ+ I G I+A+ + +H FVC C K + F ++ +PYC+ + LF
Sbjct: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 425
Score = 48.9 bits (115), Expect = 9e-06
Identities = 21/61 (34%), Positives = 32/61 (52%)
Query: 363 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKL 422
+R +C+ C + I G + A+ K +HPE F CA C + F E+ YC+ C+ K
Sbjct: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
Query: 423 F 423
F
Sbjct: 366 F 366
Score = 48.5 bits (114), Expect = 1e-05
Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 190 VCGACKKPI-AGQV-VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
+C C+ PI AG + + A+G TWH FVC+ C E + + FF + +P C+K H++
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 485
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 147 bits (372), Expect = 1e-35
Identities = 71/172 (41%), Positives = 90/172 (52%), Gaps = 2/172 (1%)
Query: 247 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306
+P C +CN I + AL ++WHPE F CA C GF E+ G YC Y FA
Sbjct: 417 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 476
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P+CG C R IL ISAL WH CFVC C P N F DG+PYCE Y+ G+
Sbjct: 477 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 536
Query: 367 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416
+C GC+ PI + A+ +H FVC+ C + L TF + DKP C+
Sbjct: 537 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588
Score = 146 bits (369), Expect = 3e-35
Identities = 66/174 (37%), Positives = 88/174 (50%), Gaps = 2/174 (1%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
+C C + I G + A+GK+WHPE F C HC+ + F E G YCE Y F+P
Sbjct: 419 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 478
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 309
C C IL +V++AL +TWH F C CG FH +DG+ YC DY+ +F C
Sbjct: 479 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 538
Query: 310 GGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 361
GC I + ++ AL WH CFVC C +FF +P C+ H H
Sbjct: 539 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAH 592
Score = 82.4 bits (202), Expect = 7e-16
Identities = 39/117 (33%), Positives = 55/117 (47%)
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P C C + I ++ AL WHPE F C C F E G YCE+ Y +
Sbjct: 418 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
C CQ+ I G I+A+ + +H FVC C K + F ++ +PYC+ + LF
Sbjct: 478 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 534
Score = 48.9 bits (115), Expect = 9e-06
Identities = 21/61 (34%), Positives = 32/61 (52%)
Query: 363 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKL 422
+R +C+ C + I G + A+ K +HPE F CA C + F E+ YC+ C+ K
Sbjct: 415 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 474
Query: 423 F 423
F
Sbjct: 475 F 475
Score = 48.5 bits (114), Expect = 1e-05
Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 190 VCGACKKPI-AGQV-VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
+C C+ PI AG + + A+G TWH FVC+ C E + + FF + +P C+K H++
Sbjct: 537 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 594
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 145 bits (365), Expect = 9e-35
Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)
Query: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 249
CG+C + I G+V+ AM WHP F C C E+ F + G+ C + HN +
Sbjct: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 156
Query: 250 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 304
C C+ I ++ + +HP+HF C CG E E G+ YC + M
Sbjct: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 215
Query: 305 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
P CG C R I ++AL WH E FVC +C PF+ +E G YCE HY++
Sbjct: 216 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
Query: 365 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 421
G +C C I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 276 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
Score = 130 bits (326), Expect = 3e-30
Identities = 84/283 (29%), Positives = 128/283 (45%), Gaps = 24/283 (8%)
Query: 149 GKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPI--AGQVVTAM 206
G+TG+ S G P + +M +L A VC C+ A ++V +
Sbjct: 9 GETGTGS--GAAPAAALRWSNMSDAL------------ANAVCQRCQARFSPAERIVNSN 54
Query: 207 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALD 266
G+ +H FVC C F+E +G+ YCE D+ LF+P C C I+ +V+ A++
Sbjct: 55 GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 114
Query: 267 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK-----CGGCARAILENYI 321
WHP F C C GF + G+ CR + A C C I E +
Sbjct: 115 NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 174
Query: 322 SALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG-SLCSGCQKPITGRCI 380
+ +HP+ F C C + E G+ YC + H++ G +C C++PI GR +
Sbjct: 175 MFRSDAYHPDHFNCTHCGKE-LTAEARELKGELYC-LPCHDKMGVPICGACRRPIEGRVV 232
Query: 381 TAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
A+ K++H EHFVCA C K E+ YC+ + +LF
Sbjct: 233 NALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
Score = 118 bits (295), Expect = 1e-26
Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 186 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
+ K +C C I Q + +HP+HF CTHC +E+ + E G+ YC + +
Sbjct: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 215
Query: 246 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 305
P C C PI +VV AL + WH EHF CA+C F +EK G AYC Y +F
Sbjct: 216 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
Query: 306 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 362
C C+ I + +SALN W CF C C + + F E D +P C+ Y +
Sbjct: 276 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
Score = 101 bits (251), Expect = 1e-21
Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)
Query: 164 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 217
G +L + L+ +L +K+GV +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 192 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 246
Query: 218 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 277
C++ +E+ G YCE Y+ LF CY C+ I VV+AL++ W F C+
Sbjct: 247 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 306
Query: 278 QCGAFFGPEG-FHEKDGKAYCRKDY 301
C + + F E D K C++ Y
Sbjct: 307 TCNSKLTLKNKFVEFDMKPVCKRCY 331
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 145 bits (365), Expect = 9e-35
Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)
Query: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 249
CG+C + I G+V+ AM WHP F C C E+ F + G+ C + HN +
Sbjct: 71 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 129
Query: 250 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 304
C C+ I ++ + +HP+HF C CG E E G+ YC + M
Sbjct: 130 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 188
Query: 305 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
P CG C R I ++AL WH E FVC +C PF+ +E G YCE HY++
Sbjct: 189 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 248
Query: 365 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 421
G +C C I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 249 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306
Score = 129 bits (325), Expect = 4e-30
Identities = 76/246 (30%), Positives = 116/246 (47%), Gaps = 10/246 (4%)
Query: 186 VAKGVCGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 243
+A VC C+ A ++V + G+ +H FVC C F+E +G+ YCE D+
Sbjct: 5 LANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ 64
Query: 244 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 303
LF+P C C I+ +V+ A++ WHP F C C GF + G+ CR +
Sbjct: 65 MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNR 124
Query: 304 MFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEV 358
A C C I E + + +HP+ F C C + E G+ YC +
Sbjct: 125 EKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE-LTAEARELKGELYC-L 182
Query: 359 HYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 417
H++ G +C C++PI GR + A+ K++H EHFVCA C K E+ YC+
Sbjct: 183 PCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCET 242
Query: 418 CFLKLF 423
+ +LF
Sbjct: 243 HYNQLF 248
Score = 118 bits (295), Expect = 1e-26
Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 186 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
+ K +C C I Q + +HP+HF CTHC +E+ + E G+ YC + +
Sbjct: 130 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 188
Query: 246 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 305
P C C PI +VV AL + WH EHF CA+C F +EK G AYC Y +F
Sbjct: 189 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 248
Query: 306 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 362
C C+ I + +SALN W CF C C + + F E D +P C+ Y +
Sbjct: 249 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306
Score = 101 bits (251), Expect = 1e-21
Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)
Query: 164 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 217
G +L + L+ +L +K+GV +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 165 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 219
Query: 218 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 277
C++ +E+ G YCE Y+ LF CY C+ I VV+AL++ W F C+
Sbjct: 220 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 279
Query: 278 QCGAFFGPEG-FHEKDGKAYCRKDY 301
C + + F E D K C++ Y
Sbjct: 280 TCNSKLTLKNKFVEFDMKPVCKRCY 304
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 145 bits (365), Expect = 9e-35
Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)
Query: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 249
CG+C + I G+V+ AM WHP F C C E+ F + G+ C + HN +
Sbjct: 76 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 134
Query: 250 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 304
C C+ I ++ + +HP+HF C CG E E G+ YC + M
Sbjct: 135 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 193
Query: 305 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
P CG C R I ++AL WH E FVC +C PF+ +E G YCE HY++
Sbjct: 194 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 253
Query: 365 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 421
G +C C I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 254 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311
Score = 130 bits (328), Expect = 2e-30
Identities = 81/262 (30%), Positives = 121/262 (46%), Gaps = 17/262 (6%)
Query: 170 MLGSLQSDLNKLGVATVAKGVCGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSR 227
M GS SD +A VC C+ A ++V + G+ +H FVC C
Sbjct: 1 MTGSNMSD-------ALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEG 53
Query: 228 NFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG 287
F+E +G+ YCE D+ LF+P C C I+ +V+ A++ WHP F C C G
Sbjct: 54 LFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLG 113
Query: 288 FHEKDGKAYCRKDYFDMFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPF 342
F + G+ CR + A C C I E + + +HP+ F C C
Sbjct: 114 FVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE- 172
Query: 343 VNGSFFEHDGQPYCEVHYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQL 401
+ E G+ YC + H++ G +C C++PI GR + A+ K++H EHFVCA C K
Sbjct: 173 LTAEARELKGELYC-LPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF 231
Query: 402 NKGTFKEQNDKPYCQNCFLKLF 423
E+ YC+ + +LF
Sbjct: 232 LGHRHYEKKGLAYCETHYNQLF 253
Score = 118 bits (295), Expect = 1e-26
Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 186 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
+ K +C C I Q + +HP+HF CTHC +E+ + E G+ YC + +
Sbjct: 135 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 193
Query: 246 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 305
P C C PI +VV AL + WH EHF CA+C F +EK G AYC Y +F
Sbjct: 194 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 253
Query: 306 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 362
C C+ I + +SALN W CF C C + + F E D +P C+ Y +
Sbjct: 254 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311
Score = 101 bits (251), Expect = 1e-21
Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)
Query: 164 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 217
G +L + L+ +L +K+GV +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 170 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 224
Query: 218 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 277
C++ +E+ G YCE Y+ LF CY C+ I VV+AL++ W F C+
Sbjct: 225 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 284
Query: 278 QCGAFFGPEG-FHEKDGKAYCRKDY 301
C + + F E D K C++ Y
Sbjct: 285 TCNSKLTLKNKFVEFDMKPVCKRCY 309
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 145 bits (365), Expect = 9e-35
Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)
Query: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 249
CG+C + I G+V+ AM WHP F C C E+ F + G+ C + HN +
Sbjct: 100 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 158
Query: 250 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 304
C C+ I ++ + +HP+HF C CG E E G+ YC + M
Sbjct: 159 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 217
Query: 305 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
P CG C R I ++AL WH E FVC +C PF+ +E G YCE HY++
Sbjct: 218 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 277
Query: 365 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 421
G +C C I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 278 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335
Score = 129 bits (325), Expect = 4e-30
Identities = 76/246 (30%), Positives = 116/246 (47%), Gaps = 10/246 (4%)
Query: 186 VAKGVCGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 243
+A VC C+ A ++V + G+ +H FVC C F+E +G+ YCE D+
Sbjct: 34 LANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ 93
Query: 244 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 303
LF+P C C I+ +V+ A++ WHP F C C GF + G+ CR +
Sbjct: 94 MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNR 153
Query: 304 MFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEV 358
A C C I E + + +HP+ F C C + E G+ YC +
Sbjct: 154 EKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE-LTAEARELKGELYC-L 211
Query: 359 HYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 417
H++ G +C C++PI GR + A+ K++H EHFVCA C K E+ YC+
Sbjct: 212 PCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCET 271
Query: 418 CFLKLF 423
+ +LF
Sbjct: 272 HYNQLF 277
Score = 118 bits (295), Expect = 1e-26
Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 186 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
+ K +C C I Q + +HP+HF CTHC +E+ + E G+ YC + +
Sbjct: 159 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 217
Query: 246 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 305
P C C PI +VV AL + WH EHF CA+C F +EK G AYC Y +F
Sbjct: 218 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 277
Query: 306 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 362
C C+ I + +SALN W CF C C + + F E D +P C+ Y +
Sbjct: 278 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335
Score = 101 bits (251), Expect = 1e-21
Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)
Query: 164 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 217
G +L + L+ +L +K+GV +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 194 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 248
Query: 218 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 277
C++ +E+ G YCE Y+ LF CY C+ I VV+AL++ W F C+
Sbjct: 249 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 308
Query: 278 QCGAFFGPEG-FHEKDGKAYCRKDY 301
C + + F E D K C++ Y
Sbjct: 309 TCNSKLTLKNKFVEFDMKPVCKRCY 333
>gi|194272207 actin binding LIM protein family, member 2 isoform 7
[Homo sapiens]
Length = 470
Score = 139 bits (350), Expect = 5e-33
Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
+C C G+V+ K +H + FVC C ++ FF R G+ C DY L+ R
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 299
C+ C+ I +VV+AL +T+HP+ F CA C F P +GK C+K
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 300 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357
+ CGGC I + AL+ WH CF C+ C +N + DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
Query: 358 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404
YH + G C C+K ITGR + A K +HP +C C + +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
Score = 30.0 bits (66), Expect = 4.1
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
LC+ C G + K FH + FVC C L +G F + + C + +L+
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 139 bits (350), Expect = 5e-33
Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
+C C G+V+ K +H + FVC C ++ FF R G+ C DY L+ R
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 299
C+ C+ I +VV+AL +T+HP+ F CA C F P +GK C+K
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 300 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357
+ CGGC I + AL+ WH CF C+ C +N + DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
Query: 358 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404
YH + G C C+K ITGR + A K +HP +C C + +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
Score = 30.0 bits (66), Expect = 4.1
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
LC+ C G + K FH + FVC C L +G F + + C + +L+
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
>gi|194272204 actin binding LIM protein family, member 2 isoform 5
[Homo sapiens]
Length = 531
Score = 139 bits (350), Expect = 5e-33
Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
+C C G+V+ K +H + FVC C ++ FF R G+ C DY L+ R
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 299
C+ C+ I +VV+AL +T+HP+ F CA C F P +GK C+K
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 300 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357
+ CGGC I + AL+ WH CF C+ C +N + DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
Query: 358 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404
YH + G C C+K ITGR + A K +HP +C C + +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
Score = 30.0 bits (66), Expect = 4.1
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
LC+ C G + K FH + FVC C L +G F + + C + +L+
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
>gi|194272202 actin binding LIM protein family, member 2 isoform 4
[Homo sapiens]
Length = 559
Score = 139 bits (350), Expect = 5e-33
Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
+C C G+V+ K +H + FVC C ++ FF R G+ C DY L+ R
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 299
C+ C+ I +VV+AL +T+HP+ F CA C F P +GK C+K
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 300 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357
+ CGGC I + AL+ WH CF C+ C +N + DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
Query: 358 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404
YH + G C C+K ITGR + A K +HP +C C + +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
Score = 30.0 bits (66), Expect = 4.1
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
LC+ C G + K FH + FVC C L +G F + + C + +L+
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
>gi|194272200 actin binding LIM protein family, member 2 isoform 3
[Homo sapiens]
Length = 572
Score = 139 bits (350), Expect = 5e-33
Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
+C C G+V+ K +H + FVC C ++ FF R G+ C DY L+ R
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 299
C+ C+ I +VV+AL +T+HP+ F CA C F P +GK C+K
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 300 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357
+ CGGC I + AL+ WH CF C+ C +N + DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
Query: 358 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404
YH + G C C+K ITGR + A K +HP +C C + +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
Score = 30.0 bits (66), Expect = 4.1
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
LC+ C G + K FH + FVC C L +G F + + C + +L+
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
>gi|194272198 actin binding LIM protein family, member 2 isoform 2
[Homo sapiens]
Length = 611
Score = 139 bits (350), Expect = 5e-33
Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
+C C G+V+ K +H + FVC C ++ FF R G+ C DY L+ R
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 299
C+ C+ I +VV+AL +T+HP+ F CA C F P +GK C+K
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 300 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357
+ CGGC I + AL+ WH CF C+ C +N + DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
Query: 358 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404
YH + G C C+K ITGR + A K +HP +C C + +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
Score = 30.0 bits (66), Expect = 4.1
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
LC+ C G + K FH + FVC C L +G F + + C + +L+
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
>gi|194272196 actin binding LIM protein family, member 2 isoform 1
[Homo sapiens]
Length = 645
Score = 139 bits (350), Expect = 5e-33
Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
+C C G+V+ K +H + FVC C ++ FF R G+ C DY L+ R
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 299
C+ C+ I +VV+AL +T+HP+ F CA C F P +GK C+K
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 300 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357
+ CGGC I + AL+ WH CF C+ C +N + DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
Query: 358 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404
YH + G C C+K ITGR + A K +HP +C C + +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
Score = 30.0 bits (66), Expect = 4.1
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
LC+ C G + K FH + FVC C L +G F + + C + +L+
Sbjct: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 137 bits (344), Expect = 2e-32
Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)
Query: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 270
E F C HC E + + + R+ PYC + LF+ C C PI D K ++ DR WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 328
F C+QC + F K+ + C Y + ++ KC C + I+ + + W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388
H CF+C C P SF D Q +C Y ++ C C+KPIT +T + +H
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
Query: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
E FVC C KQL+ F ++D YC NCF L+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
Score = 112 bits (281), Expect = 5e-25
Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)
Query: 191 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248
C CKK I + + G +WH F+C CQ+ IG+++F +D Q +C Y +
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
Query: 249 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 308
+C C PI VT ++ WH E F C C + F +D AYC + D++A K
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
Query: 309 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
C GC I YIS WH +CF C++C V F ER
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268
Query: 365 GSLCSGCQKPI 375
LC C K I
Sbjct: 269 DILCPDCGKDI 279
Score = 106 bits (265), Expect = 3e-23
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)
Query: 185 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 242
T+ C C KPI ++ + WH F C+ C+ + + F ++ Q C Y
Sbjct: 34 TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93
Query: 243 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300
N +S +C C I+ + + +WH F C +C G + F KD + +C
Sbjct: 94 SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
Query: 301 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360
Y A +C C + I ++ WH ECFVC C F D YC +
Sbjct: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
Query: 361 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416
+ C+GC PI+G + I+ +++H + F C C L F + D C
Sbjct: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273
Query: 417 NC 418
+C
Sbjct: 274 DC 275
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 137 bits (344), Expect = 2e-32
Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)
Query: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 270
E F C HC E + + + R+ PYC + LF+ C C PI D K ++ DR WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 328
F C+QC + F K+ + C Y + ++ KC C + I+ + + W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388
H CF+C C P SF D Q +C Y ++ C C+KPIT +T + +H
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
Query: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
E FVC C KQL+ F ++D YC NCF L+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
Score = 112 bits (281), Expect = 5e-25
Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)
Query: 191 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248
C CKK I + + G +WH F+C CQ+ IG+++F +D Q +C Y +
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
Query: 249 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 308
+C C PI VT ++ WH E F C C + F +D AYC + D++A K
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
Query: 309 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
C GC I YIS WH +CF C++C V F ER
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268
Query: 365 GSLCSGCQKPI 375
LC C K I
Sbjct: 269 DILCPDCGKDI 279
Score = 106 bits (265), Expect = 3e-23
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)
Query: 185 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 242
T+ C C KPI ++ + WH F C+ C+ + + F ++ Q C Y
Sbjct: 34 TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93
Query: 243 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300
N +S +C C I+ + + +WH F C +C G + F KD + +C
Sbjct: 94 SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
Query: 301 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360
Y A +C C + I ++ WH ECFVC C F D YC +
Sbjct: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
Query: 361 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416
+ C+GC PI+G + I+ +++H + F C C L F + D C
Sbjct: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273
Query: 417 NC 418
+C
Sbjct: 274 DC 275
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 137 bits (344), Expect = 2e-32
Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)
Query: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 270
E F C HC E + + + R+ PYC + LF+ C C PI D K ++ DR WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 328
F C+QC + F K+ + C Y + ++ KC C + I+ + + W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388
H CF+C C P SF D Q +C Y ++ C C+KPIT +T + +H
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
Query: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
E FVC C KQL+ F ++D YC NCF L+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
Score = 112 bits (281), Expect = 5e-25
Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)
Query: 191 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248
C CKK I + + G +WH F+C CQ+ IG+++F +D Q +C Y +
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
Query: 249 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 308
+C C PI VT ++ WH E F C C + F +D AYC + D++A K
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
Query: 309 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
C GC I YIS WH +CF C++C V F ER
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268
Query: 365 GSLCSGCQKPI 375
LC C K I
Sbjct: 269 DILCPDCGKDI 279
Score = 106 bits (265), Expect = 3e-23
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)
Query: 185 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 242
T+ C C KPI ++ + WH F C+ C+ + + F ++ Q C Y
Sbjct: 34 TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93
Query: 243 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300
N +S +C C I+ + + +WH F C +C G + F KD + +C
Sbjct: 94 SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
Query: 301 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360
Y A +C C + I ++ WH ECFVC C F D YC +
Sbjct: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
Query: 361 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416
+ C+GC PI+G + I+ +++H + F C C L F + D C
Sbjct: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273
Query: 417 NC 418
+C
Sbjct: 274 DC 275
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 137 bits (344), Expect = 2e-32
Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)
Query: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 270
E F C HC E + + + R+ PYC + LF+ C C PI D K ++ DR WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 328
F C+QC + F K+ + C Y + ++ KC C + I+ + + W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388
H CF+C C P SF D Q +C Y ++ C C+KPIT +T + +H
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
Query: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
E FVC C KQL+ F ++D YC NCF L+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
Score = 112 bits (281), Expect = 5e-25
Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)
Query: 191 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248
C CKK I + + G +WH F+C CQ+ IG+++F +D Q +C Y +
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
Query: 249 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 308
+C C PI VT ++ WH E F C C + F +D AYC + D++A K
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
Query: 309 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
C GC I YIS WH +CF C++C V F ER
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268
Query: 365 GSLCSGCQKPI 375
LC C K I
Sbjct: 269 DILCPDCGKDI 279
Score = 106 bits (265), Expect = 3e-23
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)
Query: 185 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 242
T+ C C KPI ++ + WH F C+ C+ + + F ++ Q C Y
Sbjct: 34 TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93
Query: 243 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300
N +S +C C I+ + + +WH F C +C G + F KD + +C
Sbjct: 94 SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
Query: 301 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360
Y A +C C + I ++ WH ECFVC C F D YC +
Sbjct: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
Query: 361 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416
+ C+GC PI+G + I+ +++H + F C C L F + D C
Sbjct: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273
Query: 417 NC 418
+C
Sbjct: 274 DC 275
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 131 bits (330), Expect = 1e-30
Identities = 62/173 (35%), Positives = 86/173 (49%), Gaps = 2/173 (1%)
Query: 247 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306
+P C+ C+ I + + AL +HPE F C+QCG GF E+ G +C Y +A
Sbjct: 245 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 304
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P C C + I + AL WH CF C C TP N +F+ +G PYCE Y + G+
Sbjct: 305 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 364
Query: 367 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 417
C GC I R + A+ +H FVCA C L TF + D+P C++
Sbjct: 365 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKS 417
Score = 127 bits (318), Expect = 2e-29
Identities = 60/172 (34%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
VC C K I G+ + A+G +HPE FVC+ C + + FFE G +C Y ++P
Sbjct: 247 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 306
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 309
C C I +++ AL TWH F CA C F+ ++G YC +DY MF KC
Sbjct: 307 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 366
Query: 310 GGCARAI--LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVH 359
GC I + ++ AL WH CFVC C +F+ +P C+ H
Sbjct: 367 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 418
Score = 89.0 bits (219), Expect = 8e-18
Identities = 40/114 (35%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
Query: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 250
C CKK I G+++ A+ TWH F C C+ I +R F+ +G PYCE+DY +F +C
Sbjct: 307 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 366
Query: 251 YYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 302
+ C+ I D+ + AL +WH F CA C + F+ K + C+ F
Sbjct: 367 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAF 420
Score = 83.2 bits (204), Expect = 4e-16
Identities = 40/117 (34%), Positives = 55/117 (47%)
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P C C + I Y+ AL +HPE FVC +C G FFE G +C Y R
Sbjct: 246 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
C+ C+K ITG + A+ +H F CA C + F + PYC+ + K+F
Sbjct: 306 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 362
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 131 bits (330), Expect = 1e-30
Identities = 62/173 (35%), Positives = 86/173 (49%), Gaps = 2/173 (1%)
Query: 247 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306
+P C+ C+ I + + AL +HPE F C+QCG GF E+ G +C Y +A
Sbjct: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P C C + I + AL WH CF C C TP N +F+ +G PYCE Y + G+
Sbjct: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398
Query: 367 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 417
C GC I R + A+ +H FVCA C L TF + D+P C++
Sbjct: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKS 451
Score = 127 bits (318), Expect = 2e-29
Identities = 60/172 (34%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
Query: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
VC C K I G+ + A+G +HPE FVC+ C + + FFE G +C Y ++P
Sbjct: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 309
C C I +++ AL TWH F CA C F+ ++G YC +DY MF KC
Sbjct: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
Query: 310 GGCARAI--LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVH 359
GC I + ++ AL WH CFVC C +F+ +P C+ H
Sbjct: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
Score = 89.0 bits (219), Expect = 8e-18
Identities = 40/114 (35%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
Query: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 250
C CKK I G+++ A+ TWH F C C+ I +R F+ +G PYCE+DY +F +C
Sbjct: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
Query: 251 YYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 302
+ C+ I D+ + AL +WH F CA C + F+ K + C+ F
Sbjct: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAF 454
Score = 83.2 bits (204), Expect = 4e-16
Identities = 40/117 (34%), Positives = 55/117 (47%)
Query: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
P C C + I Y+ AL +HPE FVC +C G FFE G +C Y R
Sbjct: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
C+ C+K ITG + A+ +H F CA C + F + PYC+ + K+F
Sbjct: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 124 bits (311), Expect = 2e-28
Identities = 69/224 (30%), Positives = 102/224 (45%), Gaps = 11/224 (4%)
Query: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 250
C C +P G+V+ K +H + F C C ++ FF ++G+ C DY ++ RC
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRC 98
Query: 251 YYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG---FHEKD------GKAYCRKDY 301
+ C + +VVTAL +T+HP F C C F P F+ +D +
Sbjct: 99 HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK 158
Query: 302 FDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360
F+ C GC R I + AL+ WH CF C+ C + G + DG PYCE Y
Sbjct: 159 ETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC-GKVLTGEYISKDGAPYCEKDY 217
Query: 361 HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404
G C C + ITG+ + A K +HP C+ C + +G
Sbjct: 218 QGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEG 261
Score = 93.6 bits (231), Expect = 3e-19
Identities = 54/184 (29%), Positives = 81/184 (44%), Gaps = 11/184 (5%)
Query: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 309
C+ C P +V+ + +H + F C CG GF K+G+ C DY M+ +C
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRC 98
Query: 310 GGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDG---------QPYCEVHY 360
GC + ++AL +HP CF C C PF G +G QP
Sbjct: 99 HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK 158
Query: 361 HERRGSLCSGCQKPI-TGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 419
S C+GC + I G+ + A+ K++H F C C K L G + ++ PYC+ +
Sbjct: 159 ETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDY 217
Query: 420 LKLF 423
LF
Sbjct: 218 QGLF 221
Score = 85.1 bits (209), Expect = 1e-16
Identities = 57/180 (31%), Positives = 74/180 (41%), Gaps = 39/180 (21%)
Query: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEI--GSRNFFE-RD------GQPYCEKD 241
C C + + G+VVTA+GKT+HP F CT C+ G R F RD QP
Sbjct: 98 CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 157
Query: 242 YHNLFSPRCYYCNGPILD-KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300
FS C C I + + + ALD+ WH F C CG E + KDG YC KD
Sbjct: 158 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKD 216
Query: 301 YFDMFAPKCGGCARAILENYISALN----------------------------TLWHPEC 332
Y +F KC C + I + A + T+WHP+C
Sbjct: 217 YQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDC 276
Score = 33.1 bits (74), Expect = 0.49
Identities = 17/65 (26%), Positives = 28/65 (43%)
Query: 359 HYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 418
H E+ C C +P G + K FH + F C C L +G F +N + C
Sbjct: 30 HPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLD 89
Query: 419 FLKLF 423
+ +++
Sbjct: 90 YQRMY 94
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,271,339
Number of Sequences: 37866
Number of extensions: 1110856
Number of successful extensions: 6903
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 219
Number of HSP's that attempted gapping in prelim test: 5579
Number of HSP's gapped (non-prelim): 929
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.