Search of human proteins with 170932516

Search of human proteins with 170932516

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170932516 paxillin isoform 2 [Homo sapiens]
         (557 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|170932516 paxillin isoform 2 [Homo sapiens]                       1176   0.0  
gi|170932514 paxillin isoform 1 [Homo sapiens]                       1159   0.0  
gi|170932518 paxillin isoform 3 [Homo sapiens]                        905   0.0  
gi|221316659 leupaxin isoform 1 [Homo sapiens]                        444   e-124
gi|4758670 leupaxin isoform 2 [Homo sapiens]                          444   e-124
gi|109638745 transforming growth factor beta 1 induced transcrip...   441   e-124
gi|21361591 transforming growth factor beta 1 induced transcript...   433   e-121
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]             163   4e-40
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]            161   1e-39
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ...   149   9e-36
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]            147   2e-35
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]            147   2e-35
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo...   145   1e-34
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo...   145   1e-34
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo...   145   1e-34
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor...   145   1e-34
gi|194272207 actin binding LIM protein family, member 2 isoform ...   139   7e-33
gi|153792514 actin binding LIM protein family, member 2 isoform ...   139   7e-33
gi|194272204 actin binding LIM protein family, member 2 isoform ...   139   7e-33
gi|194272202 actin binding LIM protein family, member 2 isoform ...   139   7e-33
gi|194272200 actin binding LIM protein family, member 2 isoform ...   139   7e-33
gi|194272198 actin binding LIM protein family, member 2 isoform ...   139   7e-33
gi|194272196 actin binding LIM protein family, member 2 isoform ...   139   7e-33
gi|87159836 four and a half LIM domains 2 [Homo sapiens]              137   3e-32
gi|87159834 four and a half LIM domains 2 [Homo sapiens]              137   3e-32
gi|42403575 four and a half LIM domains 2 [Homo sapiens]              137   3e-32
gi|87159832 four and a half LIM domains 2 [Homo sapiens]              137   3e-32
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]             131   1e-30
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]             131   1e-30
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]      124   2e-28

>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score = 1176 bits (3043), Expect = 0.0
 Identities = 557/557 (100%), Positives = 557/557 (100%)

Query: 1   MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNG 60
           MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNG
Sbjct: 1   MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNG 60

Query: 61  TILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSF 120
           TILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSF
Sbjct: 61  TILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSF 120

Query: 121 PNKQKSAEPSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPL 180
           PNKQKSAEPSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPL
Sbjct: 121 PNKQKSAEPSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPL 180

Query: 181 YGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQG 240
           YGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQG
Sbjct: 181 YGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQG 240

Query: 241 EMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQL 300
           EMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQL
Sbjct: 241 EMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQL 300

Query: 301 DSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSR 360
           DSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSR
Sbjct: 301 DSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSR 360

Query: 361 NFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG 420
           NFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG
Sbjct: 361 NFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG 420

Query: 421 FHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF 480
           FHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF
Sbjct: 421 FHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF 480

Query: 481 FEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK 540
           FEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK
Sbjct: 481 FEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK 540

Query: 541 EQNDKPYCQNCFLKLFC 557
           EQNDKPYCQNCFLKLFC
Sbjct: 541 EQNDKPYCQNCFLKLFC 557


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score = 1159 bits (2998), Expect = 0.0
 Identities = 557/591 (94%), Positives = 557/591 (94%), Gaps = 34/591 (5%)

Query: 1   MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNG 60
           MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNG
Sbjct: 1   MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNG 60

Query: 61  TILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSF 120
           TILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSF
Sbjct: 61  TILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSF 120

Query: 121 PNKQKSAEPSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPL 180
           PNKQKSAEPSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPL
Sbjct: 121 PNKQKSAEPSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPL 180

Query: 181 YGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQG 240
           YGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQG
Sbjct: 181 YGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQG 240

Query: 241 EMSSPQRVTSTQQQTRISASSATRELDELMASLSDFK----------------------- 277
           EMSSPQRVTSTQQQTRISASSATRELDELMASLSDFK                       
Sbjct: 241 EMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKIQGLEQRADGERCWAAGWPRDGG 300

Query: 278 -----------FMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGA 326
                      FMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGA
Sbjct: 301 RSSPGGQDEGGFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGA 360

Query: 327 CKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYC 386
           CKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYC
Sbjct: 361 CKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYC 420

Query: 387 NGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCA 446
           NGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCA
Sbjct: 421 NGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCA 480

Query: 447 RAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQK 506
           RAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQK
Sbjct: 481 RAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQK 540

Query: 507 PITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC 557
           PITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC
Sbjct: 541 PITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC 591


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score =  905 bits (2340), Expect = 0.0
 Identities = 424/424 (100%), Positives = 424/424 (100%)

Query: 134 MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 193
           MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK
Sbjct: 1   MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 60

Query: 194 AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 253
           AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ
Sbjct: 61  AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 120

Query: 254 QTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 313
           QTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNK
Sbjct: 121 QTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 180

Query: 314 LGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK 373
           LGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK
Sbjct: 181 LGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK 240

Query: 374 DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 433
           DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD
Sbjct: 241 DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300

Query: 434 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 493
           YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY
Sbjct: 301 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360

Query: 494 HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 553
           HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL
Sbjct: 361 HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 420

Query: 554 KLFC 557
           KLFC
Sbjct: 421 KLFC 424


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score =  444 bits (1141), Expect = e-124
 Identities = 203/335 (60%), Positives = 245/335 (73%), Gaps = 12/335 (3%)

Query: 230 SPVPA---ITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGS 286
           SP+PA    T N  E++        ++    S +SA  +LDELMA L++     Q K   
Sbjct: 59  SPLPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEM----QAKVAV 114

Query: 287 SSPPGGPPKPGSQ-----LDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGK 341
            +  G    P  Q     LDSMLG L+ +L  LG+ATV KG C +C+KPIAG+V+ A+G+
Sbjct: 115 RADAGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQ 174

Query: 342 TWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRT 401
           +WHPEHFVCTHC+EEIGS  FFER G  YC  DYH LFSPRC YC  PILDKV+TA+++T
Sbjct: 175 SWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQT 234

Query: 402 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLW 461
           WHPEHFFC+ CG  FG EGFHEKD K YCRKD+  MF+PKCGGC R +LENY+SA++T+W
Sbjct: 235 WHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVW 294

Query: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521
           HPECFVC +CFT F  GSFFE DG+P+CE+HYH RRG+LC GC +PITGRCI+AM  KFH
Sbjct: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354

Query: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           PEHFVCAFCL QL+KG F+EQNDK YCQ CF KLF
Sbjct: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score =  444 bits (1141), Expect = e-124
 Identities = 203/335 (60%), Positives = 245/335 (73%), Gaps = 12/335 (3%)

Query: 230 SPVPA---ITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGS 286
           SP+PA    T N  E++        ++    S +SA  +LDELMA L++     Q K   
Sbjct: 54  SPLPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEM----QAKVAV 109

Query: 287 SSPPGGPPKPGSQ-----LDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGK 341
            +  G    P  Q     LDSMLG L+ +L  LG+ATV KG C +C+KPIAG+V+ A+G+
Sbjct: 110 RADAGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQ 169

Query: 342 TWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRT 401
           +WHPEHFVCTHC+EEIGS  FFER G  YC  DYH LFSPRC YC  PILDKV+TA+++T
Sbjct: 170 SWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQT 229

Query: 402 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLW 461
           WHPEHFFC+ CG  FG EGFHEKD K YCRKD+  MF+PKCGGC R +LENY+SA++T+W
Sbjct: 230 WHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVW 289

Query: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521
           HPECFVC +CFT F  GSFFE DG+P+CE+HYH RRG+LC GC +PITGRCI+AM  KFH
Sbjct: 290 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 349

Query: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           PEHFVCAFCL QL+KG F+EQNDK YCQ CF KLF
Sbjct: 350 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score =  441 bits (1134), Expect = e-124
 Identities = 250/576 (43%), Positives = 312/576 (54%), Gaps = 136/576 (23%)

Query: 1   MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNG 60
           M+DLDALL+DLE+TTSH+ +         P   P             P+ PPPS      
Sbjct: 1   MEDLDALLSDLETTTSHMPR------SGAPKERPA-----------EPLTPPPS------ 37

Query: 61  TILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSF 120
                                      YG          PQ   G      G+++H+YS 
Sbjct: 38  ---------------------------YG--------HQPQTGSGESSGASGDKDHLYST 62

Query: 121 ---PNKQKSAEPSPTVMSTS---LGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLP 174
              P   K A P+    S+S   LG+ L ELDRLL ELNA Q N      DE  S     
Sbjct: 63  VCKPRSPKPAAPAAPPFSSSSGVLGTGLCELDRLLQELNATQFN----ITDEIMSQ---- 114

Query: 175 GALSPLYGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPA 234
                    P +    G +    +++K            RPS+ S          SP P 
Sbjct: 115 --------FPSSKVASGEQKEDQSEDKK-----------RPSLPS----------SPSPG 145

Query: 235 ITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFM----AQGKT------ 284
           +                    + SA+SAT ELD LMASLSDF+      A G T      
Sbjct: 146 L-------------------PKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVS 186

Query: 285 ----GSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMG 340
               GS SPP   P     LD+MLG LQSDL++ GV T AKG+CG+C KPIAGQVVTA+G
Sbjct: 187 STNEGSPSPP--EPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALG 244

Query: 341 KTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDR 400
           + WHPEHFVC  C   +G  +FFE+DG P+C + Y   FSPRC +CN PI  K+VTAL  
Sbjct: 245 RAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGT 304

Query: 401 TWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTL 460
            WHPEHF C  CG  FG EGFHE++G+ YCR+D+  +FAP+C GC   IL+NYISAL+ L
Sbjct: 305 HWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSAL 364

Query: 461 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKF 520
           WHP+CFVCRECF PF  GSFFEH+G+P CE H+H RRGSLC+ C  P+TGRC++A+ ++F
Sbjct: 365 WHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRF 424

Query: 521 HPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           HP+HF C FCL+ L KG+F+E+  KPYCQ CFLKLF
Sbjct: 425 HPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 460


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score =  433 bits (1113), Expect = e-121
 Identities = 231/497 (46%), Positives = 292/497 (58%), Gaps = 86/497 (17%)

Query: 80  QPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSFPNKQKSAEPS----PTVMS 135
           +P +  P YG   +T S        G      G+++H+YS   K +S +P+    P   S
Sbjct: 13  EPLTPPPSYGHQPQTGS--------GESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSS 64

Query: 136 TS--LGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPLYGVPETNSPLGGK 193
           +S  LG+ L ELDRLL ELNA Q N      DE  S              P +    G +
Sbjct: 65  SSGVLGTGLCELDRLLQELNATQFN----ITDEIMSQ------------FPSSKVASGEQ 108

Query: 194 AGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQ 253
               +++K            RPS+ S          SP P +                  
Sbjct: 109 KEDQSEDKK-----------RPSLPS----------SPSPGL------------------ 129

Query: 254 QTRISASSATRELDELMASLSDFKFM----AQGKT----------GSSSPPGGPPKPGSQ 299
             + SA+SAT ELD LMASLSDF+      A G T          GS SPP   P     
Sbjct: 130 -PKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPP--EPTGKGS 186

Query: 300 LDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGS 359
           LD+MLG LQSDL++ GV T AKG+CG+C KPIAGQVVTA+G+ WHPEHFVC  C   +G 
Sbjct: 187 LDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGG 246

Query: 360 RNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPE 419
            +FFE+DG P+C + Y   FSPRC +CN PI  K+VTAL   WHPEHF C  CG  FG E
Sbjct: 247 SSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDE 306

Query: 420 GFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGS 479
           GFHE++G+ YCR+D+  +FAP+C GC   IL+NYISAL+ LWHP+CFVCRECF PF  GS
Sbjct: 307 GFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGS 366

Query: 480 FFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTF 539
           FFEH+G+P CE H+H RRGSLC+ C  P+TGRC++A+ ++FHP+HF C FCL+ L KG+F
Sbjct: 367 FFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSF 426

Query: 540 KEQNDKPYCQNCFLKLF 556
           +E+  KPYCQ CFLKLF
Sbjct: 427 QERAGKPYCQPCFLKLF 443


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score =  163 bits (412), Expect = 4e-40
 Identities = 130/497 (26%), Positives = 189/497 (38%), Gaps = 81/497 (16%)

Query: 11  LESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTILDPLDQWQ 70
           L  +++ I   PV  S+ T    P         A  P    PP + A   T +       
Sbjct: 295 LRRSSTPIEHAPVCTSQATTPLLPAS--AQPPAAASPSAASPPLATAAAHTAIASASTTA 352

Query: 71  PSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSFPNKQKSAEPS 130
           P+SS     +PQ+SS  Y  +   SS         +P +         S+     +  P 
Sbjct: 353 PASSPADSPRPQASS--YSPAVAASS---------APATHT-------SYSEGPAAPAPK 394

Query: 131 PTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGA-LSPLYGVPETNSP 189
           P V++T+                     P  +    A++  P PGA  SP    P T SP
Sbjct: 395 PRVVTTA------------------SIRPSVYQPVPASTYSPSPGANYSP---TPYTPSP 433

Query: 190 LGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVT 249
                 P     P                       +  PSPVP  T +     +P    
Sbjct: 434 -----APAYTPSPA---------------------PAYTPSPVPTYTPSPAPAYTPSPAP 467

Query: 250 STQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSS--------PPGGPP--KPGSQ 299
           +      ++ S    E       ++D  F  +   G S+        P GGP     G Q
Sbjct: 468 NYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQ 527

Query: 300 LDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGS 359
           +  +         +   A+    +CG C   I G  + AMG++WHPE F C +C+  +  
Sbjct: 528 VPPLARGTVQRAERFP-ASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLAD 586

Query: 360 RNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPE 419
             F E     YCE+ Y   F+P C  CN  I+ +V+ AL +TWH   F CA C   FG  
Sbjct: 587 VCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNS 646

Query: 420 GFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLWHPECFVCRECFTPFVN 477
            FH +DG+ YC KDY ++F+ KC GC   +   + +I AL   WH  CF+C  C      
Sbjct: 647 LFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEG 706

Query: 478 GSFFEHDGQPYCEVHYH 494
             F+    +P C+ H H
Sbjct: 707 QPFYSKKDRPLCKKHAH 723



 Score =  131 bits (330), Expect = 1e-30
 Identities = 62/172 (36%), Positives = 81/172 (47%), Gaps = 2/172 (1%)

Query: 380 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439
           +P C +CN  I    + A+ R+WHPE F CA C        F E+    YC + Y   FA
Sbjct: 548 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 607

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P C  C   I+   + AL   WH  CFVC  C  PF N  F   DG+PYCE  Y     +
Sbjct: 608 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 667

Query: 500 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549
            C GC  P+    + I A+   +H   F+CA C   L    F  + D+P C+
Sbjct: 668 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 39/117 (33%), Positives = 55/117 (47%)

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P CG C   I   ++ A+   WHPE F C  C T   +  F E     YCE  Y +    
Sbjct: 549 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 608

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           LC+ C   I G  + A+ + +H   FVCA C K      F  ++ +PYC+  ++ LF
Sbjct: 609 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 665



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 22/60 (36%), Positives = 31/60 (51%)

Query: 497 RGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           R  LC  C   I G  + AM + +HPE F CA+C   L    F E+ +  YC+ C+ + F
Sbjct: 547 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 606



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 2/57 (3%)

Query: 324 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
           C  C  P+    + + A+G TWH   F+C  C   +  + F+ +  +P C+K  H +
Sbjct: 669 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 725


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score =  161 bits (408), Expect = 1e-39
 Identities = 87/278 (31%), Positives = 125/278 (44%), Gaps = 13/278 (4%)

Query: 229 PSPVPAITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSS 288
           PSPVP  T +     +P    +      ++ S    E       ++D  F  +   G S+
Sbjct: 337 PSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKST 396

Query: 289 --------PPGGPP--KPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTA 338
                   P GGP     G Q+  +         +   A+    +CG C   I G  + A
Sbjct: 397 TSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAERFP-ASSRTPLCGHCNNVIRGPFLVA 455

Query: 339 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTAL 398
           MG++WHPE F C +C+  +    F E     YCE+ Y   F+P C  CN  I+ +V+ AL
Sbjct: 456 MGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHAL 515

Query: 399 DRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISA 456
            +TWH   F CA C   FG   FH +DG+ YC KDY ++F+ KC GC   +   + +I A
Sbjct: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575

Query: 457 LNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 494
           L   WH  CF+C  C        F+    +P C+ H H
Sbjct: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613



 Score =  131 bits (330), Expect = 1e-30
 Identities = 62/172 (36%), Positives = 81/172 (47%), Gaps = 2/172 (1%)

Query: 380 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439
           +P C +CN  I    + A+ R+WHPE F CA C        F E+    YC + Y   FA
Sbjct: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P C  C   I+   + AL   WH  CFVC  C  PF N  F   DG+PYCE  Y     +
Sbjct: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557

Query: 500 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549
            C GC  P+    + I A+   +H   F+CA C   L    F  + D+P C+
Sbjct: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 39/117 (33%), Positives = 55/117 (47%)

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P CG C   I   ++ A+   WHPE F C  C T   +  F E     YCE  Y +    
Sbjct: 439 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           LC+ C   I G  + A+ + +H   FVCA C K      F  ++ +PYC+  ++ LF
Sbjct: 499 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 22/60 (36%), Positives = 31/60 (51%)

Query: 497 RGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           R  LC  C   I G  + AM + +HPE F CA+C   L    F E+ +  YC+ C+ + F
Sbjct: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 2/57 (3%)

Query: 324 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
           C  C  P+    + + A+G TWH   F+C  C   +  + F+ +  +P C+K  H +
Sbjct: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 615


>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 325

 Score =  149 bits (375), Expect = 9e-36
 Identities = 80/238 (33%), Positives = 117/238 (49%), Gaps = 9/238 (3%)

Query: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 382
           C  C + I G+V+ AM  +WHPE F C  CQE +    F +  G+  C +  HN    R 
Sbjct: 71  CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARG 129

Query: 383 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 437
                C  C+  I ++ +   +  +HP+HF CA CG     +   E  G+ YC   +  M
Sbjct: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKM 188

Query: 438 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
             P CG C R I    ++A+   WH E FVC +C  PF+    +E  G  YCE HY++  
Sbjct: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248

Query: 498 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 554
           G +C  C + I G  ++A+ K +    F C+ C  +L  K  F E + KP C+ C+ K
Sbjct: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306



 Score =  138 bits (348), Expect = 1e-32
 Identities = 79/246 (32%), Positives = 121/246 (49%), Gaps = 10/246 (4%)

Query: 319 VAKGVCGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 376
           +A   C  CK   A   ++V + G+ +H + FVC  C ++     F+E +G+ YCE D+ 
Sbjct: 5   LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64

Query: 377 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 436
            LF+P C+ C   I+ +V+ A++ +WHPE F C  C       GF +  G+  CR  +  
Sbjct: 65  MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 124

Query: 437 MFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEV 491
             A       C  C   I E  +   N  +HP+ F C  C    +     E  G+ YC +
Sbjct: 125 EKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKE-LTADARELKGELYC-L 182

Query: 492 HYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 550
             H++ G  +C  C++PI GR + AM K++H EHFVCA C K        E+    YC+ 
Sbjct: 183 PCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCET 242

Query: 551 CFLKLF 556
            + +LF
Sbjct: 243 HYNQLF 248



 Score =  114 bits (285), Expect = 2e-25
 Identities = 60/178 (33%), Positives = 86/178 (48%), Gaps = 2/178 (1%)

Query: 319 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
           + K +C  C   I  Q +      +HP+HF C +C +E+ + +  E  G+ YC   +  +
Sbjct: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKM 188

Query: 379 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 438
             P C  C  PI  +VV A+ + WH EHF CA+C   F     +E+ G AYC   Y  +F
Sbjct: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248

Query: 439 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 495
              C  C R I  + +SALN  W   CF C  C T   +   F E D +P C+  Y +
Sbjct: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306



 Score =  105 bits (263), Expect = 8e-23
 Identities = 52/124 (41%), Positives = 70/124 (56%), Gaps = 6/124 (4%)

Query: 312 NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 371
           +K+GV      +CGAC++PI G+VV AMGK WH EHFVC  C++       +ER G  YC
Sbjct: 186 DKMGVP-----ICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240

Query: 372 EKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG-FHEKDGKAYC 430
           E  Y+ LF   C++CN  I   VV+AL++ W    F C+ C      +  F E D K  C
Sbjct: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300

Query: 431 RKDY 434
           +K Y
Sbjct: 301 KKCY 304


>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
          Length = 487

 Score =  147 bits (372), Expect = 2e-35
 Identities = 71/172 (41%), Positives = 90/172 (52%), Gaps = 2/172 (1%)

Query: 380 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439
           +P C +CN  I    + AL ++WHPE F CA C       GF E+ G  YC   Y   FA
Sbjct: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P+CG C R IL   ISAL   WH  CFVC  C  P  N  F   DG+PYCE  Y+   G+
Sbjct: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427

Query: 500 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549
           +C GC+ PI      + A+   +H   FVC+ C + L   TF  + DKP C+
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479



 Score =  146 bits (369), Expect = 4e-35
 Identities = 66/174 (37%), Positives = 88/174 (50%), Gaps = 2/174 (1%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           +C  C + I G  + A+GK+WHPE F C HC+  +    F E  G  YCE  Y   F+P 
Sbjct: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 442
           C  C   IL +V++AL +TWH   F C  CG       FH +DG+ YC  DY+ +F   C
Sbjct: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429

Query: 443 GGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 494
            GC   I   + ++ AL   WH  CFVC  C       +FF    +P C+ H H
Sbjct: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAH 483



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 39/117 (33%), Positives = 55/117 (47%)

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P C  C + I   ++ AL   WHPE F C  C        F E  G  YCE+ Y +    
Sbjct: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
            C  CQ+ I G  I+A+ + +H   FVC  C K +    F  ++ +PYC+  +  LF
Sbjct: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 425



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 21/61 (34%), Positives = 32/61 (52%)

Query: 496 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKL 555
           +R  +C+ C + I G  + A+ K +HPE F CA C   +    F E+    YC+ C+ K 
Sbjct: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365

Query: 556 F 556
           F
Sbjct: 366 F 366



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 2/58 (3%)

Query: 323 VCGACKKPI-AGQV-VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
           +C  C+ PI AG + + A+G TWH   FVC+ C E +  + FF +  +P C+K  H++
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 485


>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
          Length = 596

 Score =  147 bits (372), Expect = 2e-35
 Identities = 71/172 (41%), Positives = 90/172 (52%), Gaps = 2/172 (1%)

Query: 380 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439
           +P C +CN  I    + AL ++WHPE F CA C       GF E+ G  YC   Y   FA
Sbjct: 417 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 476

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P+CG C R IL   ISAL   WH  CFVC  C  P  N  F   DG+PYCE  Y+   G+
Sbjct: 477 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 536

Query: 500 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549
           +C GC+ PI      + A+   +H   FVC+ C + L   TF  + DKP C+
Sbjct: 537 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588



 Score =  146 bits (369), Expect = 4e-35
 Identities = 66/174 (37%), Positives = 88/174 (50%), Gaps = 2/174 (1%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           +C  C + I G  + A+GK+WHPE F C HC+  +    F E  G  YCE  Y   F+P 
Sbjct: 419 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 478

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 442
           C  C   IL +V++AL +TWH   F C  CG       FH +DG+ YC  DY+ +F   C
Sbjct: 479 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 538

Query: 443 GGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 494
            GC   I   + ++ AL   WH  CFVC  C       +FF    +P C+ H H
Sbjct: 539 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAH 592



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 39/117 (33%), Positives = 55/117 (47%)

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P C  C + I   ++ AL   WHPE F C  C        F E  G  YCE+ Y +    
Sbjct: 418 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
            C  CQ+ I G  I+A+ + +H   FVC  C K +    F  ++ +PYC+  +  LF
Sbjct: 478 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 534



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 21/61 (34%), Positives = 32/61 (52%)

Query: 496 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKL 555
           +R  +C+ C + I G  + A+ K +HPE F CA C   +    F E+    YC+ C+ K 
Sbjct: 415 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 474

Query: 556 F 556
           F
Sbjct: 475 F 475



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 2/58 (3%)

Query: 323 VCGACKKPI-AGQV-VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
           +C  C+ PI AG + + A+G TWH   FVC+ C E +  + FF +  +P C+K  H++
Sbjct: 537 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 594


>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
           1 [Homo sapiens]
          Length = 363

 Score =  145 bits (365), Expect = 1e-34
 Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)

Query: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 382
           CG+C + I G+V+ AM   WHP  F C  C  E+    F +  G+  C +  HN    + 
Sbjct: 98  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 156

Query: 383 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 437
                C  C+  I ++ +      +HP+HF C  CG     E   E  G+ YC   +  M
Sbjct: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 215

Query: 438 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
             P CG C R I    ++AL   WH E FVC +C  PF+    +E  G  YCE HY++  
Sbjct: 216 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275

Query: 498 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 554
           G +C  C   I G  ++A+ K +    F C+ C  +L  K  F E + KP C+ C+ K
Sbjct: 276 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333



 Score =  130 bits (326), Expect = 4e-30
 Identities = 84/283 (29%), Positives = 128/283 (45%), Gaps = 24/283 (8%)

Query: 282 GKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPI--AGQVVTAM 339
           G+TG+ S  G  P    +  +M  +L            A  VC  C+     A ++V + 
Sbjct: 9   GETGTGS--GAAPAAALRWSNMSDAL------------ANAVCQRCQARFSPAERIVNSN 54

Query: 340 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALD 399
           G+ +H   FVC  C        F+E +G+ YCE D+  LF+P C  C   I+ +V+ A++
Sbjct: 55  GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 114

Query: 400 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK-----CGGCARAILENYI 454
             WHP  F C  C       GF +  G+  CR  +    A       C  C   I E  +
Sbjct: 115 NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 174

Query: 455 SALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG-SLCSGCQKPITGRCI 513
              +  +HP+ F C  C    +     E  G+ YC +  H++ G  +C  C++PI GR +
Sbjct: 175 MFRSDAYHPDHFNCTHCGKE-LTAEARELKGELYC-LPCHDKMGVPICGACRRPIEGRVV 232

Query: 514 TAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
            A+ K++H EHFVCA C K        E+    YC+  + +LF
Sbjct: 233 NALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275



 Score =  118 bits (295), Expect = 2e-26
 Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)

Query: 319 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
           + K +C  C   I  Q +      +HP+HF CTHC +E+ +    E  G+ YC   +  +
Sbjct: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 215

Query: 379 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 438
             P C  C  PI  +VV AL + WH EHF CA+C   F     +EK G AYC   Y  +F
Sbjct: 216 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275

Query: 439 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 495
              C  C+  I  + +SALN  W   CF C  C +   +   F E D +P C+  Y +
Sbjct: 276 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333



 Score =  101 bits (251), Expect = 2e-21
 Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)

Query: 297 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 350
           G +L +    L+ +L      +K+GV      +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 192 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 246

Query: 351 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 410
             C++       +E+ G  YCE  Y+ LF   CY C+  I   VV+AL++ W    F C+
Sbjct: 247 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 306

Query: 411 QCGAFFGPEG-FHEKDGKAYCRKDY 434
            C +    +  F E D K  C++ Y
Sbjct: 307 TCNSKLTLKNKFVEFDMKPVCKRCY 331


>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
           5 [Homo sapiens]
          Length = 336

 Score =  145 bits (365), Expect = 1e-34
 Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)

Query: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 382
           CG+C + I G+V+ AM   WHP  F C  C  E+    F +  G+  C +  HN    + 
Sbjct: 71  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 129

Query: 383 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 437
                C  C+  I ++ +      +HP+HF C  CG     E   E  G+ YC   +  M
Sbjct: 130 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 188

Query: 438 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
             P CG C R I    ++AL   WH E FVC +C  PF+    +E  G  YCE HY++  
Sbjct: 189 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 248

Query: 498 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 554
           G +C  C   I G  ++A+ K +    F C+ C  +L  K  F E + KP C+ C+ K
Sbjct: 249 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306



 Score =  129 bits (325), Expect = 5e-30
 Identities = 76/246 (30%), Positives = 116/246 (47%), Gaps = 10/246 (4%)

Query: 319 VAKGVCGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 376
           +A  VC  C+     A ++V + G+ +H   FVC  C        F+E +G+ YCE D+ 
Sbjct: 5   LANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ 64

Query: 377 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 436
            LF+P C  C   I+ +V+ A++  WHP  F C  C       GF +  G+  CR  +  
Sbjct: 65  MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNR 124

Query: 437 MFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEV 491
             A       C  C   I E  +   +  +HP+ F C  C    +     E  G+ YC +
Sbjct: 125 EKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE-LTAEARELKGELYC-L 182

Query: 492 HYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 550
             H++ G  +C  C++PI GR + A+ K++H EHFVCA C K        E+    YC+ 
Sbjct: 183 PCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCET 242

Query: 551 CFLKLF 556
            + +LF
Sbjct: 243 HYNQLF 248



 Score =  118 bits (295), Expect = 2e-26
 Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)

Query: 319 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
           + K +C  C   I  Q +      +HP+HF CTHC +E+ +    E  G+ YC   +  +
Sbjct: 130 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 188

Query: 379 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 438
             P C  C  PI  +VV AL + WH EHF CA+C   F     +EK G AYC   Y  +F
Sbjct: 189 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 248

Query: 439 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 495
              C  C+  I  + +SALN  W   CF C  C +   +   F E D +P C+  Y +
Sbjct: 249 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306



 Score =  101 bits (251), Expect = 2e-21
 Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)

Query: 297 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 350
           G +L +    L+ +L      +K+GV      +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 165 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 219

Query: 351 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 410
             C++       +E+ G  YCE  Y+ LF   CY C+  I   VV+AL++ W    F C+
Sbjct: 220 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 279

Query: 411 QCGAFFGPEG-FHEKDGKAYCRKDY 434
            C +    +  F E D K  C++ Y
Sbjct: 280 TCNSKLTLKNKFVEFDMKPVCKRCY 304


>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
           3 [Homo sapiens]
          Length = 341

 Score =  145 bits (365), Expect = 1e-34
 Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)

Query: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 382
           CG+C + I G+V+ AM   WHP  F C  C  E+    F +  G+  C +  HN    + 
Sbjct: 76  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 134

Query: 383 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 437
                C  C+  I ++ +      +HP+HF C  CG     E   E  G+ YC   +  M
Sbjct: 135 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 193

Query: 438 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
             P CG C R I    ++AL   WH E FVC +C  PF+    +E  G  YCE HY++  
Sbjct: 194 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 253

Query: 498 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 554
           G +C  C   I G  ++A+ K +    F C+ C  +L  K  F E + KP C+ C+ K
Sbjct: 254 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311



 Score =  130 bits (328), Expect = 2e-30
 Identities = 81/262 (30%), Positives = 121/262 (46%), Gaps = 17/262 (6%)

Query: 303 MLGSLQSDLNKLGVATVAKGVCGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSR 360
           M GS  SD        +A  VC  C+     A ++V + G+ +H   FVC  C       
Sbjct: 1   MTGSNMSD-------ALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEG 53

Query: 361 NFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG 420
            F+E +G+ YCE D+  LF+P C  C   I+ +V+ A++  WHP  F C  C       G
Sbjct: 54  LFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLG 113

Query: 421 FHEKDGKAYCRKDYFDMFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPF 475
           F +  G+  CR  +    A       C  C   I E  +   +  +HP+ F C  C    
Sbjct: 114 FVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE- 172

Query: 476 VNGSFFEHDGQPYCEVHYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQL 534
           +     E  G+ YC +  H++ G  +C  C++PI GR + A+ K++H EHFVCA C K  
Sbjct: 173 LTAEARELKGELYC-LPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF 231

Query: 535 NKGTFKEQNDKPYCQNCFLKLF 556
                 E+    YC+  + +LF
Sbjct: 232 LGHRHYEKKGLAYCETHYNQLF 253



 Score =  118 bits (295), Expect = 2e-26
 Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)

Query: 319 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
           + K +C  C   I  Q +      +HP+HF CTHC +E+ +    E  G+ YC   +  +
Sbjct: 135 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 193

Query: 379 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 438
             P C  C  PI  +VV AL + WH EHF CA+C   F     +EK G AYC   Y  +F
Sbjct: 194 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 253

Query: 439 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 495
              C  C+  I  + +SALN  W   CF C  C +   +   F E D +P C+  Y +
Sbjct: 254 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311



 Score =  101 bits (251), Expect = 2e-21
 Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)

Query: 297 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 350
           G +L +    L+ +L      +K+GV      +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 170 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 224

Query: 351 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 410
             C++       +E+ G  YCE  Y+ LF   CY C+  I   VV+AL++ W    F C+
Sbjct: 225 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 284

Query: 411 QCGAFFGPEG-FHEKDGKAYCRKDY 434
            C +    +  F E D K  C++ Y
Sbjct: 285 TCNSKLTLKNKFVEFDMKPVCKRCY 309


>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
           [Homo sapiens]
          Length = 365

 Score =  145 bits (365), Expect = 1e-34
 Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)

Query: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 382
           CG+C + I G+V+ AM   WHP  F C  C  E+    F +  G+  C +  HN    + 
Sbjct: 100 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 158

Query: 383 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 437
                C  C+  I ++ +      +HP+HF C  CG     E   E  G+ YC   +  M
Sbjct: 159 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 217

Query: 438 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
             P CG C R I    ++AL   WH E FVC +C  PF+    +E  G  YCE HY++  
Sbjct: 218 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 277

Query: 498 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 554
           G +C  C   I G  ++A+ K +    F C+ C  +L  K  F E + KP C+ C+ K
Sbjct: 278 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335



 Score =  129 bits (325), Expect = 5e-30
 Identities = 76/246 (30%), Positives = 116/246 (47%), Gaps = 10/246 (4%)

Query: 319 VAKGVCGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 376
           +A  VC  C+     A ++V + G+ +H   FVC  C        F+E +G+ YCE D+ 
Sbjct: 34  LANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ 93

Query: 377 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 436
            LF+P C  C   I+ +V+ A++  WHP  F C  C       GF +  G+  CR  +  
Sbjct: 94  MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNR 153

Query: 437 MFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEV 491
             A       C  C   I E  +   +  +HP+ F C  C    +     E  G+ YC +
Sbjct: 154 EKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE-LTAEARELKGELYC-L 211

Query: 492 HYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 550
             H++ G  +C  C++PI GR + A+ K++H EHFVCA C K        E+    YC+ 
Sbjct: 212 PCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCET 271

Query: 551 CFLKLF 556
            + +LF
Sbjct: 272 HYNQLF 277



 Score =  118 bits (295), Expect = 2e-26
 Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)

Query: 319 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
           + K +C  C   I  Q +      +HP+HF CTHC +E+ +    E  G+ YC   +  +
Sbjct: 159 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 217

Query: 379 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 438
             P C  C  PI  +VV AL + WH EHF CA+C   F     +EK G AYC   Y  +F
Sbjct: 218 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 277

Query: 439 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 495
              C  C+  I  + +SALN  W   CF C  C +   +   F E D +P C+  Y +
Sbjct: 278 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335



 Score =  101 bits (251), Expect = 2e-21
 Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)

Query: 297 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 350
           G +L +    L+ +L      +K+GV      +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 194 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 248

Query: 351 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 410
             C++       +E+ G  YCE  Y+ LF   CY C+  I   VV+AL++ W    F C+
Sbjct: 249 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 308

Query: 411 QCGAFFGPEG-FHEKDGKAYCRKDY 434
            C +    +  F E D K  C++ Y
Sbjct: 309 TCNSKLTLKNKFVEFDMKPVCKRCY 333


>gi|194272207 actin binding LIM protein family, member 2 isoform 7
           [Homo sapiens]
          Length = 470

 Score =  139 bits (350), Expect = 7e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 432
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142

Query: 433 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201

Query: 491 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79


>gi|153792514 actin binding LIM protein family, member 2 isoform 6
           [Homo sapiens]
          Length = 521

 Score =  139 bits (350), Expect = 7e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 432
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142

Query: 433 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201

Query: 491 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79


>gi|194272204 actin binding LIM protein family, member 2 isoform 5
           [Homo sapiens]
          Length = 531

 Score =  139 bits (350), Expect = 7e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 432
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142

Query: 433 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201

Query: 491 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79


>gi|194272202 actin binding LIM protein family, member 2 isoform 4
           [Homo sapiens]
          Length = 559

 Score =  139 bits (350), Expect = 7e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 432
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142

Query: 433 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201

Query: 491 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79


>gi|194272200 actin binding LIM protein family, member 2 isoform 3
           [Homo sapiens]
          Length = 572

 Score =  139 bits (350), Expect = 7e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 432
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142

Query: 433 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201

Query: 491 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79


>gi|194272198 actin binding LIM protein family, member 2 isoform 2
           [Homo sapiens]
          Length = 611

 Score =  139 bits (350), Expect = 7e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 432
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142

Query: 433 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201

Query: 491 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79


>gi|194272196 actin binding LIM protein family, member 2 isoform 1
           [Homo sapiens]
          Length = 645

 Score =  139 bits (350), Expect = 7e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 432
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142

Query: 433 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201

Query: 491 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79


>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  137 bits (344), Expect = 3e-32
 Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)

Query: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 403
           E F C HC E +  + +  R+  PYC   +  LF+  C  C  PI  D K ++  DR WH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 461
              F C+QC      + F  K+ +  C   Y + ++ KC  C + I+     +    + W
Sbjct: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122

Query: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521
           H  CF+C  C  P    SF   D Q +C   Y ++    C  C+KPIT   +T   + +H
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182

Query: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
            E FVC  C KQL+   F  ++D  YC NCF  L+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217



 Score =  112 bits (281), Expect = 7e-25
 Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)

Query: 324 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381
           C  CKK I    + +   G +WH   F+C  CQ+ IG+++F  +D Q +C   Y    + 
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160

Query: 382 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 441
           +C  C  PI    VT  ++ WH E F C  C      + F  +D  AYC   + D++A K
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220

Query: 442 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
           C GC   I       YIS     WH +CF C++C    V   F              ER 
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268

Query: 498 GSLCSGCQKPI 508
             LC  C K I
Sbjct: 269 DILCPDCGKDI 279



 Score =  106 bits (265), Expect = 5e-23
 Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)

Query: 318 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 375
           T+    C  C KPI      ++   + WH   F C+ C+  +  + F  ++ Q  C   Y
Sbjct: 34  TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93

Query: 376 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 433
            N +S +C  C   I+   + +     +WH   F C +C    G + F  KD + +C   
Sbjct: 94  SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153

Query: 434 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 493
           Y    A +C  C + I    ++     WH ECFVC  C        F   D   YC   +
Sbjct: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213

Query: 494 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549
            +     C+GC  PI+G    + I+   +++H + F C  C   L    F  + D   C 
Sbjct: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273

Query: 550 NC 551
           +C
Sbjct: 274 DC 275


>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  137 bits (344), Expect = 3e-32
 Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)

Query: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 403
           E F C HC E +  + +  R+  PYC   +  LF+  C  C  PI  D K ++  DR WH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 461
              F C+QC      + F  K+ +  C   Y + ++ KC  C + I+     +    + W
Sbjct: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122

Query: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521
           H  CF+C  C  P    SF   D Q +C   Y ++    C  C+KPIT   +T   + +H
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182

Query: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
            E FVC  C KQL+   F  ++D  YC NCF  L+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217



 Score =  112 bits (281), Expect = 7e-25
 Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)

Query: 324 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381
           C  CKK I    + +   G +WH   F+C  CQ+ IG+++F  +D Q +C   Y    + 
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160

Query: 382 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 441
           +C  C  PI    VT  ++ WH E F C  C      + F  +D  AYC   + D++A K
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220

Query: 442 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
           C GC   I       YIS     WH +CF C++C    V   F              ER 
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268

Query: 498 GSLCSGCQKPI 508
             LC  C K I
Sbjct: 269 DILCPDCGKDI 279



 Score =  106 bits (265), Expect = 5e-23
 Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)

Query: 318 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 375
           T+    C  C KPI      ++   + WH   F C+ C+  +  + F  ++ Q  C   Y
Sbjct: 34  TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93

Query: 376 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 433
            N +S +C  C   I+   + +     +WH   F C +C    G + F  KD + +C   
Sbjct: 94  SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153

Query: 434 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 493
           Y    A +C  C + I    ++     WH ECFVC  C        F   D   YC   +
Sbjct: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213

Query: 494 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549
            +     C+GC  PI+G    + I+   +++H + F C  C   L    F  + D   C 
Sbjct: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273

Query: 550 NC 551
           +C
Sbjct: 274 DC 275


>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  137 bits (344), Expect = 3e-32
 Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)

Query: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 403
           E F C HC E +  + +  R+  PYC   +  LF+  C  C  PI  D K ++  DR WH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 461
              F C+QC      + F  K+ +  C   Y + ++ KC  C + I+     +    + W
Sbjct: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122

Query: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521
           H  CF+C  C  P    SF   D Q +C   Y ++    C  C+KPIT   +T   + +H
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182

Query: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
            E FVC  C KQL+   F  ++D  YC NCF  L+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217



 Score =  112 bits (281), Expect = 7e-25
 Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)

Query: 324 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381
           C  CKK I    + +   G +WH   F+C  CQ+ IG+++F  +D Q +C   Y    + 
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160

Query: 382 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 441
           +C  C  PI    VT  ++ WH E F C  C      + F  +D  AYC   + D++A K
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220

Query: 442 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
           C GC   I       YIS     WH +CF C++C    V   F              ER 
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268

Query: 498 GSLCSGCQKPI 508
             LC  C K I
Sbjct: 269 DILCPDCGKDI 279



 Score =  106 bits (265), Expect = 5e-23
 Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)

Query: 318 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 375
           T+    C  C KPI      ++   + WH   F C+ C+  +  + F  ++ Q  C   Y
Sbjct: 34  TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93

Query: 376 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 433
            N +S +C  C   I+   + +     +WH   F C +C    G + F  KD + +C   
Sbjct: 94  SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153

Query: 434 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 493
           Y    A +C  C + I    ++     WH ECFVC  C        F   D   YC   +
Sbjct: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213

Query: 494 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549
            +     C+GC  PI+G    + I+   +++H + F C  C   L    F  + D   C 
Sbjct: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273

Query: 550 NC 551
           +C
Sbjct: 274 DC 275


>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  137 bits (344), Expect = 3e-32
 Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)

Query: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 403
           E F C HC E +  + +  R+  PYC   +  LF+  C  C  PI  D K ++  DR WH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 461
              F C+QC      + F  K+ +  C   Y + ++ KC  C + I+     +    + W
Sbjct: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122

Query: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521
           H  CF+C  C  P    SF   D Q +C   Y ++    C  C+KPIT   +T   + +H
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182

Query: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
            E FVC  C KQL+   F  ++D  YC NCF  L+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217



 Score =  112 bits (281), Expect = 7e-25
 Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)

Query: 324 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381
           C  CKK I    + +   G +WH   F+C  CQ+ IG+++F  +D Q +C   Y    + 
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160

Query: 382 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 441
           +C  C  PI    VT  ++ WH E F C  C      + F  +D  AYC   + D++A K
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220

Query: 442 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
           C GC   I       YIS     WH +CF C++C    V   F              ER 
Sbjct: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268

Query: 498 GSLCSGCQKPI 508
             LC  C K I
Sbjct: 269 DILCPDCGKDI 279



 Score =  106 bits (265), Expect = 5e-23
 Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)

Query: 318 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 375
           T+    C  C KPI      ++   + WH   F C+ C+  +  + F  ++ Q  C   Y
Sbjct: 34  TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93

Query: 376 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 433
            N +S +C  C   I+   + +     +WH   F C +C    G + F  KD + +C   
Sbjct: 94  SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153

Query: 434 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 493
           Y    A +C  C + I    ++     WH ECFVC  C        F   D   YC   +
Sbjct: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213

Query: 494 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549
            +     C+GC  PI+G    + I+   +++H + F C  C   L    F  + D   C 
Sbjct: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273

Query: 550 NC 551
           +C
Sbjct: 274 DC 275


>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
          Length = 423

 Score =  131 bits (330), Expect = 1e-30
 Identities = 62/173 (35%), Positives = 86/173 (49%), Gaps = 2/173 (1%)

Query: 380 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439
           +P C+ C+  I  + + AL   +HPE F C+QCG      GF E+ G  +C   Y   +A
Sbjct: 245 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 304

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P C  C + I    + AL   WH  CF C  C TP  N +F+  +G PYCE  Y +  G+
Sbjct: 305 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 364

Query: 500 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 550
            C GC   I    R + A+   +H   FVCA C   L   TF  + D+P C++
Sbjct: 365 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKS 417



 Score =  127 bits (318), Expect = 3e-29
 Identities = 60/172 (34%), Positives = 84/172 (48%), Gaps = 2/172 (1%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           VC  C K I G+ + A+G  +HPE FVC+ C + +    FFE  G  +C   Y   ++P 
Sbjct: 247 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 306

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 442
           C  C   I  +++ AL  TWH   F CA C        F+ ++G  YC +DY  MF  KC
Sbjct: 307 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 366

Query: 443 GGCARAI--LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVH 492
            GC   I   + ++ AL   WH  CFVC  C       +F+    +P C+ H
Sbjct: 367 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 418



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 40/114 (35%), Positives = 60/114 (52%), Gaps = 2/114 (1%)

Query: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 383
           C  CKK I G+++ A+  TWH   F C  C+  I +R F+  +G PYCE+DY  +F  +C
Sbjct: 307 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 366

Query: 384 YYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 435
           + C+  I   D+ + AL  +WH   F CA C      + F+ K  +  C+   F
Sbjct: 367 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAF 420



 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 40/117 (34%), Positives = 55/117 (47%)

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P C  C + I   Y+ AL   +HPE FVC +C      G FFE  G  +C   Y  R   
Sbjct: 246 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
            C+ C+K ITG  + A+   +H   F CA C   +    F  +   PYC+  + K+F
Sbjct: 306 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 362


>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
          Length = 457

 Score =  131 bits (330), Expect = 1e-30
 Identities = 62/173 (35%), Positives = 86/173 (49%), Gaps = 2/173 (1%)

Query: 380 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439
           +P C+ C+  I  + + AL   +HPE F C+QCG      GF E+ G  +C   Y   +A
Sbjct: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P C  C + I    + AL   WH  CF C  C TP  N +F+  +G PYCE  Y +  G+
Sbjct: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398

Query: 500 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 550
            C GC   I    R + A+   +H   FVCA C   L   TF  + D+P C++
Sbjct: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKS 451



 Score =  127 bits (318), Expect = 3e-29
 Identities = 60/172 (34%), Positives = 84/172 (48%), Gaps = 2/172 (1%)

Query: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
           VC  C K I G+ + A+G  +HPE FVC+ C + +    FFE  G  +C   Y   ++P 
Sbjct: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 442
           C  C   I  +++ AL  TWH   F CA C        F+ ++G  YC +DY  MF  KC
Sbjct: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400

Query: 443 GGCARAI--LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVH 492
            GC   I   + ++ AL   WH  CFVC  C       +F+    +P C+ H
Sbjct: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 40/114 (35%), Positives = 60/114 (52%), Gaps = 2/114 (1%)

Query: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 383
           C  CKK I G+++ A+  TWH   F C  C+  I +R F+  +G PYCE+DY  +F  +C
Sbjct: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400

Query: 384 YYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 435
           + C+  I   D+ + AL  +WH   F CA C      + F+ K  +  C+   F
Sbjct: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAF 454



 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 40/117 (34%), Positives = 55/117 (47%)

Query: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
           P C  C + I   Y+ AL   +HPE FVC +C      G FFE  G  +C   Y  R   
Sbjct: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339

Query: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
            C+ C+K ITG  + A+   +H   F CA C   +    F  +   PYC+  + K+F
Sbjct: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396


>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
          Length = 746

 Score =  124 bits (311), Expect = 2e-28
 Identities = 69/224 (30%), Positives = 102/224 (45%), Gaps = 11/224 (4%)

Query: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 383
           C  C +P  G+V+    K +H + F C  C  ++    FF ++G+  C  DY  ++  RC
Sbjct: 39  CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRC 98

Query: 384 YYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG---FHEKD------GKAYCRKDY 434
           + C   +  +VVTAL +T+HP  F C  C   F P     F+ +D       +       
Sbjct: 99  HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK 158

Query: 435 FDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 493
              F+  C GC R I     + AL+  WH  CF C+ C    + G +   DG PYCE  Y
Sbjct: 159 ETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC-GKVLTGEYISKDGAPYCEKDY 217

Query: 494 HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537
               G  C  C + ITG+ + A  K +HP    C+ C +   +G
Sbjct: 218 QGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEG 261



 Score = 93.6 bits (231), Expect = 4e-19
 Identities = 54/184 (29%), Positives = 81/184 (44%), Gaps = 11/184 (5%)

Query: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 442
           C+ C  P   +V+    + +H + F C  CG      GF  K+G+  C  DY  M+  +C
Sbjct: 39  CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRC 98

Query: 443 GGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDG---------QPYCEVHY 493
            GC   +    ++AL   +HP CF C  C  PF  G     +G         QP      
Sbjct: 99  HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK 158

Query: 494 HERRGSLCSGCQKPI-TGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 552
                S C+GC + I  G+ + A+ K++H   F C  C K L  G +  ++  PYC+  +
Sbjct: 159 ETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDY 217

Query: 553 LKLF 556
             LF
Sbjct: 218 QGLF 221



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 57/180 (31%), Positives = 74/180 (41%), Gaps = 39/180 (21%)

Query: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEI--GSRNFFE-RD------GQPYCEKD 374
           C  C + + G+VVTA+GKT+HP  F CT C+     G R  F  RD       QP     
Sbjct: 98  CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 157

Query: 375 YHNLFSPRCYYCNGPILD-KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 433
               FS  C  C   I + + + ALD+ WH   F C  CG     E +  KDG  YC KD
Sbjct: 158 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKD 216

Query: 434 YFDMFAPKCGGCARAILENYISALN----------------------------TLWHPEC 465
           Y  +F  KC  C + I    + A +                            T+WHP+C
Sbjct: 217 YQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDC 276



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 17/65 (26%), Positives = 28/65 (43%)

Query: 492 HYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 551
           H  E+    C  C +P  G  +    K FH + F C  C   L +G F  +N +  C   
Sbjct: 30  HPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLD 89

Query: 552 FLKLF 556
           + +++
Sbjct: 90  YQRMY 94


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,253,317
Number of Sequences: 37866
Number of extensions: 1563155
Number of successful extensions: 12185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 451
Number of HSP's that attempted gapping in prelim test: 9978
Number of HSP's gapped (non-prelim): 2039
length of query: 557
length of database: 18,247,518
effective HSP length: 107
effective length of query: 450
effective length of database: 14,195,856
effective search space: 6388135200
effective search space used: 6388135200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.