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Search of human proteins with 170763519
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170763519 transforming, acidic coiled-coil containing
protein 1 isoform 2 [Homo sapiens]
(395 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170763519 transforming, acidic coiled-coil containing protein... 774 0.0
gi|170763517 transforming, acidic coiled-coil containing protein... 664 0.0
gi|226246618 transforming, acidic coiled-coil containing protein... 664 0.0
gi|150418009 transforming, acidic coiled-coil containing protein... 298 7e-81
gi|45827755 transforming, acidic coiled-coil containing protein ... 298 7e-81
gi|45827753 transforming, acidic coiled-coil containing protein ... 298 7e-81
gi|11119414 transforming, acidic coiled-coil containing protein ... 298 7e-81
gi|5454102 transforming, acidic coiled-coil containing protein 3... 209 5e-54
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 56 5e-08
gi|156104908 myosin heavy chain 6 [Homo sapiens] 55 8e-08
gi|71061468 centromere protein E [Homo sapiens] 55 1e-07
gi|31982906 cingulin-like 1 [Homo sapiens] 55 1e-07
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 54 2e-07
gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo sa... 54 2e-07
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 53 4e-07
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 53 5e-07
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 53 5e-07
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 53 5e-07
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 53 5e-07
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 53 5e-07
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 53 5e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 52 7e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 51 2e-06
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 51 2e-06
gi|56550043 sarcolemma associated protein [Homo sapiens] 51 2e-06
gi|58530840 desmoplakin isoform I [Homo sapiens] 51 2e-06
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 50 3e-06
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 50 3e-06
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 50 4e-06
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 50 4e-06
>gi|170763519 transforming, acidic coiled-coil containing protein 1
isoform 2 [Homo sapiens]
Length = 395
Score = 774 bits (1998), Expect = 0.0
Identities = 395/395 (100%), Positives = 395/395 (100%)
Query: 1 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFRSGCKVK 60
MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFRSGCKVK
Sbjct: 1 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFRSGCKVK 60
Query: 61 KHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEED 120
KHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEED
Sbjct: 61 KHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEED 120
Query: 121 LEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGE 180
LEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGE
Sbjct: 121 LEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGE 180
Query: 181 SPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIA 240
SPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIA
Sbjct: 181 SPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIA 240
Query: 241 QMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEE 300
QMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEE
Sbjct: 241 QMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEE 300
Query: 301 ALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQ 360
ALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQ
Sbjct: 301 ALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQ 360
Query: 361 MKVESLERALQQKNQEIEELTKICDELIAKLGKTD 395
MKVESLERALQQKNQEIEELTKICDELIAKLGKTD
Sbjct: 361 MKVESLERALQQKNQEIEELTKICDELIAKLGKTD 395
>gi|170763517 transforming, acidic coiled-coil containing protein 1
isoform 1 [Homo sapiens]
Length = 805
Score = 664 bits (1713), Expect = 0.0
Identities = 347/363 (95%), Positives = 350/363 (96%), Gaps = 2/363 (0%)
Query: 35 PEGDPEEE--DSQAETKSLSFRSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGH 92
P G+ E +S + KS SGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGH
Sbjct: 443 PTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGH 502
Query: 93 ATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQK 152
ATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQK
Sbjct: 503 ATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQK 562
Query: 153 MEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEAN 212
MEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEAN
Sbjct: 563 MEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEAN 622
Query: 213 EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN 272
EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN
Sbjct: 623 EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN 682
Query: 273 SVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD 332
SVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD
Sbjct: 683 SVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD 742
Query: 333 KANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLG 392
KANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLG
Sbjct: 743 KANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLG 802
Query: 393 KTD 395
KTD
Sbjct: 803 KTD 805
Score = 117 bits (293), Expect = 2e-26
Identities = 54/55 (98%), Positives = 54/55 (98%)
Query: 1 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFRS 55
MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSF S
Sbjct: 1 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSS 55
>gi|226246618 transforming, acidic coiled-coil containing protein 1
isoform 3 [Homo sapiens]
Length = 610
Score = 664 bits (1713), Expect = 0.0
Identities = 347/363 (95%), Positives = 350/363 (96%), Gaps = 2/363 (0%)
Query: 35 PEGDPEEE--DSQAETKSLSFRSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGH 92
P G+ E +S + KS SGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGH
Sbjct: 248 PTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGH 307
Query: 93 ATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQK 152
ATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQK
Sbjct: 308 ATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQK 367
Query: 153 MEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEAN 212
MEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEAN
Sbjct: 368 MEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEAN 427
Query: 213 EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN 272
EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN
Sbjct: 428 EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN 487
Query: 273 SVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD 332
SVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD
Sbjct: 488 SVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD 547
Query: 333 KANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLG 392
KANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLG
Sbjct: 548 KANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLG 607
Query: 393 KTD 395
KTD
Sbjct: 608 KTD 610
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 298 bits (762), Expect = 7e-81
Identities = 149/210 (70%), Positives = 179/210 (85%)
Query: 185 GICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIE 244
G+ + D + L + R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIE
Sbjct: 2739 GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE 2798
Query: 245 DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 304
DEQR S ++ QQL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+
Sbjct: 2799 DEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKR 2858
Query: 305 CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVE 364
CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR KA+ E AA A LRKEQ++V+
Sbjct: 2859 CAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD 2918
Query: 365 SLERALQQKNQEIEELTKICDELIAKLGKT 394
+LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 2919 ALERTLEQKNKEIEELTKICDELIAKMGKS 2948
Score = 29.6 bits (65), Expect = 5.0
Identities = 42/161 (26%), Positives = 73/161 (45%), Gaps = 19/161 (11%)
Query: 31 EAGGPEGDPEEEDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEG-AVISQISDISNR 89
EA G +GD + ++ + L + +VKK +S D S+D A + + +
Sbjct: 2406 EANGVDGDGLNKPAKKKKTPLKTDT-FRVKKSPKRSPLSDPPSQDPTPAATPETPPVISA 2464
Query: 90 DGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET 149
HATDEEKLA T+ QK V E ++ +Y + S++ FSS ++
Sbjct: 2465 VVHATDEEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRN 2521
Query: 150 ---CQKMEEDGSTV-----------LGLLESSAEKAPVSVS 176
+ ME+ GS++ L L+ +++++PV S
Sbjct: 2522 SYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 2562
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 298 bits (762), Expect = 7e-81
Identities = 149/210 (70%), Positives = 179/210 (85%)
Query: 185 GICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIE 244
G+ + D + L + R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIE
Sbjct: 885 GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE 944
Query: 245 DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 304
DEQR S ++ QQL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+
Sbjct: 945 DEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKR 1004
Query: 305 CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVE 364
CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR KA+ E AA A LRKEQ++V+
Sbjct: 1005 CAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD 1064
Query: 365 SLERALQQKNQEIEELTKICDELIAKLGKT 394
+LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 1065 ALERTLEQKNKEIEELTKICDELIAKMGKS 1094
Score = 29.6 bits (65), Expect = 5.0
Identities = 42/161 (26%), Positives = 73/161 (45%), Gaps = 19/161 (11%)
Query: 31 EAGGPEGDPEEEDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEG-AVISQISDISNR 89
EA G +GD + ++ + L + +VKK +S D S+D A + + +
Sbjct: 552 EANGVDGDGLNKPAKKKKTPLKTDT-FRVKKSPKRSPLSDPPSQDPTPAATPETPPVISA 610
Query: 90 DGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET 149
HATDEEKLA T+ QK V E ++ +Y + S++ FSS ++
Sbjct: 611 VVHATDEEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRN 667
Query: 150 ---CQKMEEDGSTV-----------LGLLESSAEKAPVSVS 176
+ ME+ GS++ L L+ +++++PV S
Sbjct: 668 SYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 708
>gi|45827753 transforming, acidic coiled-coil containing protein 2
isoform c [Homo sapiens]
Length = 996
Score = 298 bits (762), Expect = 7e-81
Identities = 149/210 (70%), Positives = 179/210 (85%)
Query: 185 GICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIE 244
G+ + D + L + R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIE
Sbjct: 787 GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE 846
Query: 245 DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 304
DEQR S ++ QQL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+
Sbjct: 847 DEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKR 906
Query: 305 CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVE 364
CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR KA+ E AA A LRKEQ++V+
Sbjct: 907 CAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD 966
Query: 365 SLERALQQKNQEIEELTKICDELIAKLGKT 394
+LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 967 ALERTLEQKNKEIEELTKICDELIAKMGKS 996
Score = 29.6 bits (65), Expect = 5.0
Identities = 42/161 (26%), Positives = 73/161 (45%), Gaps = 19/161 (11%)
Query: 31 EAGGPEGDPEEEDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEG-AVISQISDISNR 89
EA G +GD + ++ + L + +VKK +S D S+D A + + +
Sbjct: 484 EANGVDGDGLNKPAKKKKTPLKTDT-FRVKKSPKRSPLSDPPSQDPTPAATPETPPVISA 542
Query: 90 DGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET 149
HATDEEKLA T+ QK V E ++ +Y + S++ FSS ++
Sbjct: 543 VVHATDEEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRN 599
Query: 150 ---CQKMEEDGSTV-----------LGLLESSAEKAPVSVS 176
+ ME+ GS++ L L+ +++++PV S
Sbjct: 600 SYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 640
>gi|11119414 transforming, acidic coiled-coil containing protein 2
isoform d [Homo sapiens]
Length = 1026
Score = 298 bits (762), Expect = 7e-81
Identities = 149/210 (70%), Positives = 179/210 (85%)
Query: 185 GICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIE 244
G+ + D + L + R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIE
Sbjct: 817 GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE 876
Query: 245 DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 304
DEQR S ++ QQL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+
Sbjct: 877 DEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKR 936
Query: 305 CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVE 364
CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR KA+ E AA A LRKEQ++V+
Sbjct: 937 CAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD 996
Query: 365 SLERALQQKNQEIEELTKICDELIAKLGKT 394
+LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 997 ALERTLEQKNKEIEELTKICDELIAKMGKS 1026
Score = 29.6 bits (65), Expect = 5.0
Identities = 42/161 (26%), Positives = 73/161 (45%), Gaps = 19/161 (11%)
Query: 31 EAGGPEGDPEEEDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEG-AVISQISDISNR 89
EA G +GD + ++ + L + +VKK +S D S+D A + + +
Sbjct: 484 EANGVDGDGLNKPAKKKKTPLKTDT-FRVKKSPKRSPLSDPPSQDPTPAATPETPPVISA 542
Query: 90 DGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET 149
HATDEEKLA T+ QK V E ++ +Y + S++ FSS ++
Sbjct: 543 VVHATDEEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRN 599
Query: 150 ---CQKMEEDGSTV-----------LGLLESSAEKAPVSVS 176
+ ME+ GS++ L L+ +++++PV S
Sbjct: 600 SYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 640
>gi|5454102 transforming, acidic coiled-coil containing protein 3
[Homo sapiens]
Length = 838
Score = 209 bits (531), Expect = 5e-54
Identities = 123/274 (44%), Positives = 174/274 (63%), Gaps = 20/274 (7%)
Query: 129 VPVSTIN---HAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPL-- 183
VPV+T H + + +G +E + +E D LG L+ P V G PL
Sbjct: 575 VPVATETSSMHGANETPSGRPREA-KLVEFD---FLGALDIPVPGPPPGVPAPGGPPLST 630
Query: 184 ----DGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTI 239
D + S+ D AV+ +EE E + + EE + LE+ KI+ +E+ +
Sbjct: 631 GPIVDLLQYSQKDLDAVVKATQEE-------NRELRSRCEELHGKNLELGKIMDRFEEVV 683
Query: 240 AQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNE 299
Q +E+ Q+ S+ Q++ EK+Q DLNS+E+S SDLF+R+E K V+EG++KNE
Sbjct: 684 YQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNE 743
Query: 300 EALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKE 359
E+LKKC +DYLAR+ QE QRYQALK HAEEKL ANEEIAQVR+KA+AE+ AL A LRKE
Sbjct: 744 ESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKE 803
Query: 360 QMKVESLERALQQKNQEIEELTKICDELIAKLGK 393
QM+++SLE+ ++QK +E EELT+ICD+LI+K+ K
Sbjct: 804 QMRIQSLEKTVEQKTKENEELTRICDDLISKMEK 837
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 56.2 bits (134), Expect = 5e-08
Identities = 49/206 (23%), Positives = 102/206 (49%), Gaps = 23/206 (11%)
Query: 200 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDE--QRTSMTSQKSF 257
+ +E+ +K E + KK+ ++ E+ E +K + + + Q IE E ++ S +QK
Sbjct: 238 LNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMRE-QQQIEKEIKEKDSELNQKRP 296
Query: 258 QQLTMEKEQA--LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQ 315
Q + ++ + + L + ++SL + + Y+ KG ++ +K +++K Q++ R+++
Sbjct: 297 QYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEE 356
Query: 316 EEQ--------------RYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQM 361
E Q +Y LK A ++ +E+ + KA+ L +E+
Sbjct: 357 ESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDL---EERK 413
Query: 362 KVESLERALQQKNQEIEELTKICDEL 387
KVE+ E ++QK +EIEE K ++L
Sbjct: 414 KVET-EAKIKQKLREIEENQKRIEKL 438
Score = 37.7 bits (86), Expect = 0.018
Identities = 45/197 (22%), Positives = 80/197 (40%), Gaps = 43/197 (21%)
Query: 191 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTS 250
S K L ++ + + + K +E +E+L + K E+ E+R
Sbjct: 306 SHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEF----------EERME 355
Query: 251 MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYL 310
SQ + LT+E+ Q ++Y LK EEA K+
Sbjct: 356 EESQSQGRDLTLEENQV---------------KKYHRLK---------EEASKRA----- 386
Query: 311 ARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERAL 370
A + QE +++ + +++LD EE +V T+AK + + + Q ++E LE +
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDL--EERKKVETEAKIKQKLRE--IEENQKRIEKLEEYI 442
Query: 371 QQKNQEIEELTKICDEL 387
Q +EE K+ EL
Sbjct: 443 TTSKQSLEEQKKLEGEL 459
Score = 34.3 bits (77), Expect = 0.20
Identities = 39/196 (19%), Positives = 84/196 (42%), Gaps = 35/196 (17%)
Query: 190 ESDKTAVLTLIREEIITK-EIEANEWKKKYEETR--QEVLEMRKIVAEYEKTIAQMIEDE 246
E +K +L R ++ + +E+ K E T +E+ ++ EY+K +M++ E
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAE 179
Query: 247 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA 306
+ T + + + E+++A + +R Y+ LK
Sbjct: 180 EDTQFNYHRK-KNIAAERKEAKQEKEEADR--------YQRLK----------------- 213
Query: 307 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVR---TKAKAESAALHAGLRKEQMKV 363
D + R + + Q ++ H E +++K N+E+A K K + L++++ ++
Sbjct: 214 -DEVVRAQVQLQLFKLY--HNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKEL 270
Query: 364 ESLERALQQKNQEIEE 379
+ R QQ +EI+E
Sbjct: 271 GKMMREQQQIEKEIKE 286
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 55.5 bits (132), Expect = 8e-08
Identities = 44/198 (22%), Positives = 100/198 (50%), Gaps = 10/198 (5%)
Query: 200 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 259
++++I E+ + +K+ T +V + + +A ++ IA++ ++++ Q++
Sbjct: 952 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDD 1011
Query: 260 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQR 319
L +E+++ +NS+ +S L ++ ++L+G LE KK L++ + +K ++
Sbjct: 1012 LQVEEDK----VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1067
Query: 320 YQAL---KIHAEEKLDKANEEIAQVRTKAKAE---SAALHAGLRKEQMKVESLERALQQK 373
L K+ EEKL K +I Q +K + E + L L++ Q ++E LE L+ +
Sbjct: 1068 IMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAE 1127
Query: 374 NQEIEELTKICDELIAKL 391
++ K+ +L +L
Sbjct: 1128 RTARAKVEKLRSDLSREL 1145
Score = 43.9 bits (102), Expect = 3e-04
Identities = 99/424 (23%), Positives = 178/424 (41%), Gaps = 78/424 (18%)
Query: 36 EGDPEEEDSQAETKSLSFRSGCKVKKHETQSLA-LDACSRDEGAVISQISDISNRDG--- 91
E E E SQ E +SLS K+K +SL L+ R+ + +ISD++ + G
Sbjct: 1464 ESQSELESSQKEARSLSTEL-FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGG 1522
Query: 92 -HATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETC 150
+ + EK+ +K E E LE+ E + F+ +A IE++
Sbjct: 1523 KNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGK---ILRAQLEFNQIKAEIERKLA 1579
Query: 151 QKMEE------DGSTVLGLLESSA--------EKAPVSVSCGGESPLDGICLSESDKTA- 195
+K EE + V+ L++S E V G+ I LS +++ A
Sbjct: 1580 EKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAA 1639
Query: 196 --------VLTLIREEIITKE--IEANEWKKK---YEETRQEVL-----EMRKIVAEYEK 237
+ +L+++ I + + AN+ K+ E R +L E+R +V + E+
Sbjct: 1640 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1699
Query: 238 TIA----QMIEDEQR--------TSMTSQKS-----FQQLTMEKEQALADLNSVE----R 276
+ ++IE +R TS+ +QK QL E E+A+ + + E +
Sbjct: 1700 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKK 1759
Query: 277 SLSDLFRRYENLK------GVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEK 330
+++D E LK LE KKN E K Q L +E ALK +++
Sbjct: 1760 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-----DEAEQIALK-GGKKQ 1813
Query: 331 LDKANEEIAQVRTKAKAE---SAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDEL 387
L K + ++ + +AE +A G+RK + +++ L ++ + + L + D+L
Sbjct: 1814 LQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKL 1873
Query: 388 IAKL 391
K+
Sbjct: 1874 QLKV 1877
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/194 (21%), Positives = 85/194 (43%), Gaps = 33/194 (17%)
Query: 213 EWKKKYEETRQEV-----------LEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLT 261
EWK+KYEE++ E+ E+ K+ YE+++ + +E +R + Q+ LT
Sbjct: 1457 EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL-EHLETFKRENKNLQEEISDLT 1515
Query: 262 MEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQ 321
+ + +++ +E+ L L+ LE EA + + + R + E +
Sbjct: 1516 EQLGEGGKNVHELEKVRKQLEVEKLELQSALE----EAEASLEHEEGKILRAQLE---FN 1568
Query: 322 ALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELT 381
+K E KL + +EE+ Q + R Q V+SL+ +L + + E+
Sbjct: 1569 QIKAEIERKLAEKDEEMEQAK--------------RNHQRVVDSLQTSLDAETRSRNEVL 1614
Query: 382 KICDELIAKLGKTD 395
++ ++ L + +
Sbjct: 1615 RVKKKMEGDLNEME 1628
Score = 40.4 bits (93), Expect = 0.003
Identities = 68/355 (19%), Positives = 135/355 (38%), Gaps = 47/355 (13%)
Query: 38 DPEEEDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEE 97
D EE +++ K C K + L L ++ ++ + + N +
Sbjct: 930 DEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE-NKVKNLTEEMAGLD 988
Query: 98 KLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVST----INHAFSSSEAGIEKETCQKM 153
++ + +K A E + +DL+ E +S + E +E+E +M
Sbjct: 989 EIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRM 1048
Query: 154 EEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANE 213
+ LE + K + ES +D E+DK + E++ KE + N+
Sbjct: 1049 D---------LERAKRKLEGDLKLTQESIMD----LENDKLQ----LEEKLKKKEFDINQ 1091
Query: 214 WKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNS 273
K E+ + L+++K + E + I ++ E+E T++
Sbjct: 1092 QNSKIEDEQVLALQLQKKLKENQARIEEL-EEELEAERTARAK----------------- 1133
Query: 274 VERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDK 333
VE+ SDL R E + ++ EEA + K+ E +Q ++ EE +
Sbjct: 1134 VEKLRSDLSRELEEIS------ERLEEA-GGATSVQIEMNKKREAEFQKMRRDLEEATLQ 1186
Query: 334 ANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELI 388
A +R K A L + Q + LE+ + E++++T +++I
Sbjct: 1187 HEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1241
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/185 (22%), Positives = 81/185 (43%), Gaps = 17/185 (9%)
Query: 206 TKEIEANEWKKKYEETRQEV----LEMRKIVAEYEKTIAQMIEDEQ------RTSMTSQK 255
T E +ANE++ K EE ++ + + K+ E + Q+ E E R ++ +
Sbjct: 1253 TLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQ 1312
Query: 256 SFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQ 315
+ L + E+ N++ +L + L+ E + + L++ + V Q
Sbjct: 1313 QMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQ 1372
Query: 316 EEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQ 375
+Y+ I E+L++A +++AQ A+ A++A K SLE+ +
Sbjct: 1373 WRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNA-------KCSSLEKTKHRLQN 1425
Query: 376 EIEEL 380
EIE+L
Sbjct: 1426 EIEDL 1430
Score = 34.7 bits (78), Expect = 0.15
Identities = 45/185 (24%), Positives = 78/185 (42%), Gaps = 39/185 (21%)
Query: 217 KYEETRQEVLEMR----KIVAEYEKTIAQMIE-DEQRTSMTSQKSFQQLTMEKEQALADL 271
K ET +E+ M+ +I EK+ A+ E +E+ S+ +K+ QL ++ EQ +L
Sbjct: 843 KSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD--NL 900
Query: 272 NSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKL 331
N E L + L+ A+VK+ +R E
Sbjct: 901 NDAEERCDQLIKNKIQLE---------------------AKVKEMNERL--------EDE 931
Query: 332 DKANEEIAQVRTKAKAESAALHAGLRKEQM---KVESLERALQQKNQEIEELTKICDELI 388
++ N E+ + K + E + L + ++ KVE + A + K + + E DE+I
Sbjct: 932 EEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 991
Query: 389 AKLGK 393
AKL K
Sbjct: 992 AKLTK 996
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/212 (21%), Positives = 106/212 (50%), Gaps = 16/212 (7%)
Query: 180 ESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYE----ETRQEVLEMRKIVAEY 235
+ +D + S S+KTA + I T+++E + K + E QE+L K V+E
Sbjct: 1248 QETIDELRRSVSEKTAQI------INTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSET 1301
Query: 236 EKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGF 295
++T+ ++ ++++ + ++ ME+ + + + L + +NLK + E
Sbjct: 1302 QETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEAL 1361
Query: 296 KKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAG 355
+ + LK+ ++ LA++ QE Q Q ++ +EK ++ + ++++ +SA L
Sbjct: 1362 EVKHDQLKEHIRETLAKI-QESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALL--- 1417
Query: 356 LRKEQMKVESLERALQQKNQEIEELTKICDEL 387
+ ++++ L + LQ+ + E++ + K D+L
Sbjct: 1418 --RIEIEMLGLSKRLQESHDEMKSVAKEKDDL 1447
Score = 45.8 bits (107), Expect = 7e-05
Identities = 49/224 (21%), Positives = 105/224 (46%), Gaps = 36/224 (16%)
Query: 179 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT 238
G+ P D +C E + +T +++E+ KE+E NE R+EV+ + ++ K+
Sbjct: 706 GKVPKDLLCNLELE--GKITDLQKEL-NKEVEENE------ALREEVILLSEL-----KS 751
Query: 239 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN 298
+ +E ++ + +T EK++ S++ + ++G+LE K
Sbjct: 752 LPSEVERLRKEIQDKSEELHIITSEKDKLF----------SEVVHKESRVQGLLEEIGKT 801
Query: 299 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKL-------DKANEEIAQVRTKAKAESAA 351
++ L +Y + QE Q ++ L + E+K ++ N+EI + +A+ ++
Sbjct: 802 KDDLATTQSNYKS-TDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSS 860
Query: 352 LHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 395
L G K ++ ++ E LQ+K +E++E ++L +L D
Sbjct: 861 L--GALKTELSYKTQE--LQEKTREVQERLNEMEQLKEQLENRD 900
Score = 38.1 bits (87), Expect = 0.014
Identities = 38/184 (20%), Positives = 85/184 (46%), Gaps = 12/184 (6%)
Query: 208 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA 267
EIE K+ +E+ E+ + K + ++ + ++++ E + K +E E+
Sbjct: 1420 EIEMLGLSKRLQESHDEMKSVAKEKDDLQR-LQEVLQSESDQLKENIKEIVAKHLETEEE 1478
Query: 268 L----ADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQAL 323
L L E ++++L + + +K EA+ Q+ + + ++E+++
Sbjct: 1479 LKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIK 1538
Query: 324 KIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKI 383
+I E +K NE + Q + KA+ +AL + + K+ L LQ+ +EI+ + K
Sbjct: 1539 QI--SEVQEKVNE-LKQFKEHRKAKDSALQS----IESKMLELTNRLQESQEEIQIMIKE 1591
Query: 384 CDEL 387
+E+
Sbjct: 1592 KEEM 1595
Score = 36.6 bits (83), Expect = 0.041
Identities = 61/232 (26%), Positives = 111/232 (47%), Gaps = 44/232 (18%)
Query: 163 LLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETR 222
L ES E V+ L + SESD+ ++E I KEI A K+ ET
Sbjct: 1430 LQESHDEMKSVAKEKDDLQRLQEVLQSESDQ------LKENI--KEIVA-----KHLETE 1476
Query: 223 QEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKE-QALADLNSVERSLSDL 281
+E+ + E E+TI +E R ++ S+K + T++K+ +A+ D ++ + ++
Sbjct: 1477 EELKVAHCCLKEQEETI-----NELRVNL-SEKETEISTIQKQLEAIND--KLQNKIQEI 1528
Query: 282 FRRYE--NLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIA 339
+ + E N+K + E +K E LK+ + A+ Q ++ + +L ++ EEI
Sbjct: 1529 YEKEEQFNIKQISEVQEKVNE-LKQFKEHRKAK-DSALQSIESKMLELTNRLQESQEEI- 1585
Query: 340 QVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKL 391
Q+ K KE+MK ++ ALQ + +++E TK E++AK+
Sbjct: 1586 QIMIK------------EKEEMK--RVQEALQIERDQLKENTK---EIVAKM 1620
Score = 36.2 bits (82), Expect = 0.053
Identities = 46/204 (22%), Positives = 93/204 (45%), Gaps = 16/204 (7%)
Query: 191 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKI--VAEYEKTIAQMIEDE-- 246
++K + ++E+ E EA E K K ++ Q + E+ + + ++ + Q +E+E
Sbjct: 519 TEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELS 578
Query: 247 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA 306
+ + +K Q ++K Q D +E DL E++ E K+ ++ L A
Sbjct: 579 SKVELLREKEDQ---IKKLQEYIDSQKLENIKMDLSYSLESI----EDPKQMKQTLFD-A 630
Query: 307 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESL 366
+ K+E ++ + +EK+ + Q+ + + L A K++M+V+ L
Sbjct: 631 ETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEA---KKKMQVD-L 686
Query: 367 ERALQQKNQEIEELTKICDELIAK 390
E+ LQ EI +LT + D + K
Sbjct: 687 EKELQSAFNEITKLTSLIDGKVPK 710
Score = 34.3 bits (77), Expect = 0.20
Identities = 42/216 (19%), Positives = 89/216 (41%), Gaps = 26/216 (12%)
Query: 189 SESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQM---IED 245
SES+ ++ T +++++ E ++ +++ TR ++ +++ + + I Q+ +
Sbjct: 2247 SESEFPSIKTEF-QQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNN 2305
Query: 246 EQRTSMTSQKSFQQ--LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGF-------- 295
M F++ T+ KE DL S++ LF+ Y+ LK L
Sbjct: 2306 RIIAIMNESTEFEERSATISKEWE-QDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQ 2364
Query: 296 -KKNEEALKKCAQDYLARVKQEEQRYQALK---IHAEEKLDKANEE-------IAQVRTK 344
KN + Q ++++ E K +H E K+ K +E IA+++ K
Sbjct: 2365 DNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAK 2424
Query: 345 AKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 380
+ L Q+ + + + +EIE+L
Sbjct: 2425 VHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDL 2460
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 54.7 bits (130), Expect = 1e-07
Identities = 54/259 (20%), Positives = 119/259 (45%), Gaps = 22/259 (8%)
Query: 141 SEAGIEKETCQKME--EDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLT 198
SE E ++ ++ E E G+ + LL++ + + ++ E D + E + TA+
Sbjct: 708 SEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIA--KEEQEDLLRKRERELTALKG 765
Query: 199 LIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQ 258
++EE+ + + E ++ K++Y+ Q + E + + + +A ++ ++ +
Sbjct: 766 ALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVK 825
Query: 259 QLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQ 318
L E E+ +ER ++ L R+ E+LKG +E K+ + Y ++Q E+
Sbjct: 826 LLQEENEKLQGRSEELERRVAQLQRQIEDLKG-------DEAKAKETLKKYEGEIRQLEE 878
Query: 319 RYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIE 378
+HA K +E R + E A L + + + L L++++++ E
Sbjct: 879 AL----VHAR----KEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKE 930
Query: 379 ELTKICDELIAK---LGKT 394
+L ++ +E+ + LGKT
Sbjct: 931 QLRRLKNEMENERWHLGKT 949
Score = 39.7 bits (91), Expect = 0.005
Identities = 53/255 (20%), Positives = 110/255 (43%), Gaps = 28/255 (10%)
Query: 151 QKMEEDGSTVLGLLESSAEKAP--VSVSCGGESPLDGICLSESDKTAVLTLIREEI---- 204
+K E++ + LE+ E A +S + + L ES++ L ++ E+
Sbjct: 884 RKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENER 943
Query: 205 --ITKEIEA--NEWKKKYEETRQEVLEMRKIVAEYE----KTIAQMIEDEQRTSMTSQKS 256
+ K IE E E +R LE++ + EY+ + +A+M + ++ ++KS
Sbjct: 944 WHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKS 1003
Query: 257 -FQQLTMEKEQALAD--LNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARV 313
+ M+ E L + L +R+ + + + L+ L+ + EA D V
Sbjct: 1004 RLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLV 1063
Query: 314 KQEEQRYQALKIHAE----------EKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKV 363
KQ E + L++ E E++ ++ E++ Q+R + E AA L +++ +
Sbjct: 1064 KQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAA-RQDLECDKISL 1122
Query: 364 ESLERALQQKNQEIE 378
E + L+ + +E
Sbjct: 1123 ERQNKDLKSRIIHLE 1137
Score = 30.8 bits (68), Expect = 2.2
Identities = 37/151 (24%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 253 SQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLAR 312
S + L +K + ++ ++R L + +N+K E + N E L+ + +
Sbjct: 605 STSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEE 664
Query: 313 VKQEEQRYQALKIHAEEKLDKANEEIAQV---RTKAKAESAALHAGLRKEQMKVESLERA 369
+QR + +E +L K EE+ QV R + + E L L + +++S +R+
Sbjct: 665 NSTLQQRLE----ESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRS 720
Query: 370 L-QQKNQEIEELTK----ICDELIAKLGKTD 395
++K IEEL + + D LIAK + D
Sbjct: 721 EDREKGALIEELLQAKQDLQDLLIAKEEQED 751
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 54.3 bits (129), Expect = 2e-07
Identities = 49/196 (25%), Positives = 90/196 (45%), Gaps = 21/196 (10%)
Query: 199 LIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQ 258
L E+++ KE + + + K +++ E E + + D+ + Q++ Q
Sbjct: 443 LSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQL-----DKTKQQHQEQQALQ 497
Query: 259 QLTMEK-EQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEE 317
Q T K +A DL V R + D ++ +NL+ +L+ K+N L+K +D A+++ E
Sbjct: 498 QSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGE 557
Query: 318 QRYQALKIHAEEKLDKANEEIAQVRTKAKAESAA-------LH-------AGLRKEQMKV 363
L +EK E++ Q+ K K +S + LH A LR Q +V
Sbjct: 558 GETAVLN-QLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRV 616
Query: 364 ESLERALQQKNQEIEE 379
SLE ++ + N ++ E
Sbjct: 617 LSLETSVNELNSQLNE 632
Score = 51.2 bits (121), Expect = 2e-06
Identities = 47/212 (22%), Positives = 94/212 (44%), Gaps = 15/212 (7%)
Query: 180 ESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTI 239
E+ L I + S+K ++EE+ E + K ++++ +Q+ E + + + I
Sbjct: 357 ETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEI 416
Query: 240 AQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNE 299
Q+ T ++ +L +++ + L E+ ++DL + L+ L+ N
Sbjct: 417 NQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNS 476
Query: 300 EALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKE 359
L Q L + KQ+ Q QAL+ KL +A ++ QV + + +
Sbjct: 477 TEL----QHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQ-----------IGDK 521
Query: 360 QMKVESLERALQQKNQEIEELTKICDELIAKL 391
K+++LE LQ+ + I L K ++L AK+
Sbjct: 522 DQKIQNLEALLQKSKENISLLEKEREDLYAKI 553
Score = 49.3 bits (116), Expect = 6e-06
Identities = 53/242 (21%), Positives = 108/242 (44%), Gaps = 41/242 (16%)
Query: 191 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLE-----------MRKIVAEYEKTI 239
+D L+ + E++ K + E + + ++T+Q+ E +R+ + E+ +
Sbjct: 456 ADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVL 515
Query: 240 AQMIEDEQRTS------MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYEN------ 287
Q+ + +Q+ S+++ L E+E A + + E + L + E
Sbjct: 516 RQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQE 575
Query: 288 --------LKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEE---KLDKANE 336
LK E K+ +E L Q+ A ++ + R +L+ E +L+++ E
Sbjct: 576 QVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKE 635
Query: 337 EIAQ--VRTKAKAE-----SAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIA 389
+++Q ++ KAK E AA A Q +++ + ALQ K QE+ ++T D++ A
Sbjct: 636 KVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTA 695
Query: 390 KL 391
KL
Sbjct: 696 KL 697
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/195 (21%), Positives = 86/195 (44%), Gaps = 1/195 (0%)
Query: 193 KTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMT 252
KTA TL ++ KE + E K ++ ++E K + + +A++ E + R
Sbjct: 1081 KTAKATL-EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKE 1139
Query: 253 SQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLAR 312
K ++L K +++ ++ +++ + L ++ L+G + K E K+ Q +
Sbjct: 1140 ITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQ 1199
Query: 313 VKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQ 372
VK+EE+ + I E KL +E K + A L + + ++++ Q
Sbjct: 1200 VKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQS 1259
Query: 373 KNQEIEELTKICDEL 387
+ + EL K D+L
Sbjct: 1260 SQRRVSELEKQTDDL 1274
Score = 43.1 bits (100), Expect = 4e-04
Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 1/171 (0%)
Query: 210 EANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALA 269
+ NE K+K + ++ +++ E D Q T+Q + Q E +
Sbjct: 629 QLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITT 688
Query: 270 DLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEE 329
L+ V L D L+ L+ +K+ +L++ ++ ++K+ E +K E+
Sbjct: 689 QLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQ 748
Query: 330 KLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 380
L ++ Q+ T + + L L E+ V S LQ+K++ +E +
Sbjct: 749 ALQDLQQQ-RQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESI 798
Score = 41.2 bits (95), Expect = 0.002
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 24/193 (12%)
Query: 212 NEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADL 271
NE K+ E+ ++++ ++ E + + Q E E + ++ Q+L EKE+
Sbjct: 962 NELKQSSEQKKKQIEALQ---GELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQ 1018
Query: 272 NSVERS-------LSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA---RVKQEEQRYQ 321
N+ E+S SD + R L + K EE L +D ++ ++ + + Q
Sbjct: 1019 NNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQ 1078
Query: 322 ALK-IHAEEKLDKANEEIAQVRTKAKA------ESAALHAGLRKEQMKVESLERALQQKN 374
LK A + D A +E Q++ + KA E + L E+ K+ +E + K
Sbjct: 1079 ELKTAKATLEQDSAKKE-QQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIE---EIKC 1134
Query: 375 QEIEELTKICDEL 387
++ +E+TK+ +EL
Sbjct: 1135 RQEKEITKLNEEL 1147
Score = 38.9 bits (89), Expect = 0.008
Identities = 60/280 (21%), Positives = 116/280 (41%), Gaps = 43/280 (15%)
Query: 125 ECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLD 184
+ S P++T++ SS G C K + E+ + S GGES L
Sbjct: 21 DSSATPINTVDVNNESSSEGFICPQCMKSLGSADELFKHYEAVHDAGNDS-GHGGESNL- 78
Query: 185 GICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIE 244
L D +TL+R+E+ + E K EE ++E LE + + + E ++
Sbjct: 79 --ALKRDD----VTLLRQEVQDLQASLKEEKWYSEELKKE-LEKYQGLQQQEAKPDGLVT 131
Query: 245 DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 304
D A+L S+E+ L + N+K + + F++ L
Sbjct: 132 DSS---------------------AELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLAT 170
Query: 305 CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAAL--------HAGL 356
+A +K + ++L+ AE+K+ + EE+ + T + L A L
Sbjct: 171 ----EIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVL 226
Query: 357 RKEQMKVESL-ERALQQKNQEIEELTKICDELIAKLGKTD 395
+KE ++V++L + ++ +E E+L C +L ++ ++
Sbjct: 227 KKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSE 266
Score = 37.7 bits (86), Expect = 0.018
Identities = 65/385 (16%), Positives = 146/385 (37%), Gaps = 51/385 (13%)
Query: 37 GDPEEEDSQAETKSLSFRSGCKVKKHETQSL-ALDACSRDEGAVISQISDISNRDGHATD 95
GD +++ E + + + E + L A E AV++Q+ + ++
Sbjct: 519 GDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVT 578
Query: 96 E--EKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFS--SSEAGIEKETCQ 151
+ EKL + S K A + + +E + + V ++ + + +S+ KE
Sbjct: 579 QLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVS 638
Query: 152 KMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDK-------TAVLTLIREEI 204
+++ LL SAE A + ++ LD + DK T L + ++
Sbjct: 639 QLDIQIKAKTELL-LSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKL 697
Query: 205 ITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEK 264
K+ ++ + +E +++ L + + E E I ++ D + +++ Q L ++
Sbjct: 698 QDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQR 757
Query: 265 E--------------QALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDY- 309
+ Q + V + DL ++ E L+ + + K EE + QD+
Sbjct: 758 QLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFE 817
Query: 310 -----------------------LARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAK 346
L +VK E++ ++KL K ++ + +++ +
Sbjct: 818 TLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFE 877
Query: 347 AESAALHAGLRKEQMKVESLERALQ 371
E+ A + + + L+ LQ
Sbjct: 878 KENQKGKAAILDLEKTCKELKHQLQ 902
>gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo
sapiens]
Length = 669
Score = 54.3 bits (129), Expect = 2e-07
Identities = 60/273 (21%), Positives = 109/273 (39%), Gaps = 29/273 (10%)
Query: 139 SSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGI----------CL 188
S S++G + G GLL S +P S SCG SP C+
Sbjct: 269 SHSDSGRSSSSKSTGSLGGRVAGGLLGSGTRASPDSSSCGERSPPPPPPPPSDEALLHCV 328
Query: 189 SES---DKTAVLTLIREEIITKEI--------EANEWKKKYEETRQEVLEMRKIVAEYEK 237
E D+ A L +R+ + E W+++ E R++ + ++
Sbjct: 329 LEGKLRDREAELQQLRDSLDENEATMCQAYEERQRHWQREREALREDCAAQAQRAQRAQQ 388
Query: 238 TIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKK 297
+ + Q+ Q F QL E+EQ ++ER +L R E K +
Sbjct: 389 LLQLQVFQLQQEKRQLQDDFAQLLQEREQLERRCATLEREQRELGPRLEETKWEVCQKSG 448
Query: 298 NEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLR 357
LK+ ++ A + Q+ AL++ E +A +++ R + E+A R
Sbjct: 449 EISLLKQQLKESQAELVQKGSELVALRVALREA--RATLRVSEGRARGLQEAA------R 500
Query: 358 KEQMKVESLERALQQKNQEIEELTKICDELIAK 390
++++E+ + LQ+ QE E+L + +L A+
Sbjct: 501 ARELELEACSQELQRHRQEAEQLREKAGQLDAE 533
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 53.1 bits (126), Expect = 4e-07
Identities = 85/374 (22%), Positives = 147/374 (39%), Gaps = 55/374 (14%)
Query: 20 SAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEGAV 79
S R A E+ GPEG PE ++++ ++ + SL+L + E A
Sbjct: 483 SPPRSLATEEEPPQGPEGQPEWKEAE------------ELGEDSAASLSLQLSLQREQAP 530
Query: 80 ISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFEC--------SNVPV 131
+ ++ H+ EE G E +PEE + S PV
Sbjct: 531 SPPAACEKGKEQHSQAEE---------LGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPV 581
Query: 132 STINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSES 191
+ ++ +E+ Q +E+D LLES EK + + I
Sbjct: 582 APPEQLSEAALKAMEEAVAQVLEQDQR---HLLESKQEKMQQLREKLCQEEEEEILRLHQ 638
Query: 192 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 251
K L+ +RE + K IE E + + EE+ Q + +R V + I EQ S+
Sbjct: 639 QKEQSLSSLRER-LQKAIEEEEARMREEES-QRLSWLRAQVQSSTQADEDQIRAEQEASL 696
Query: 252 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 311
QK ++L +++ A L R + E LK +E +K+E+A A++
Sbjct: 697 --QKLREELESQQKAERASLEQKNRQM------LEQLKEEIEASEKSEQAALNAAKE--- 745
Query: 312 RVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLR-KEQMKVESLERAL 370
+AL+ E+ + E +A + + AE L + L K + V SL++ +
Sbjct: 746 ---------KALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKI 796
Query: 371 QQKNQEIEELTKIC 384
Q+ Q+ E + C
Sbjct: 797 QEAQQKEEAQLQKC 810
Score = 44.3 bits (103), Expect = 2e-04
Identities = 80/389 (20%), Positives = 164/389 (42%), Gaps = 52/389 (13%)
Query: 20 SAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEGAV 79
S V GGA + A P G +++DSQ+ L + +++ + L + ++
Sbjct: 430 SPVLGGACRQ--AQQPLGIEDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRS 487
Query: 80 ISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFS 139
+ AT+EE G E + E +E E E S +S + +
Sbjct: 488 L------------ATEEEP---------PQGPEGQPEWKEAEELGEDSAASLS-LQLSLQ 525
Query: 140 SSEAGIEKETCQKMEEDGSTV--LGLLESSAEKAPVSVSCGGESPL-------DGICLSE 190
+A C+K +E S LG + AE V+ P+ + + E
Sbjct: 526 REQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPE 585
Query: 191 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTS 250
A L + EE + + +E ++ + E ++++ ++R+ + + E+ + ++ S
Sbjct: 586 QLSEAALKAM-EEAVAQVLEQDQ-RHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQS 643
Query: 251 MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDY- 309
++S + Q +E+E+A R + +R L+ ++ + +E + Q+
Sbjct: 644 LSSLRERLQKAIEEEEA--------RMREEESQRLSWLRAQVQSSTQADEDQIRAEQEAS 695
Query: 310 LARVKQE-EQRYQALKIHAEEKLDKANEEIAQ-VRTKAKAESAALHAGLRK------EQM 361
L ++++E E + +A + E+K + E++ + + K+E AAL+A K EQ+
Sbjct: 696 LQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQL 755
Query: 362 KVESLERALQQKNQEIEELTKICDELIAK 390
+ E E + + EL ++C L AK
Sbjct: 756 EGERKEAVATLEKEHSAELERLCSSLEAK 784
Score = 36.2 bits (82), Expect = 0.053
Identities = 72/308 (23%), Positives = 123/308 (39%), Gaps = 51/308 (16%)
Query: 106 QKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLE 165
+K A A ++ E +LE CS++ SS + I+ E QK E LG +E
Sbjct: 759 RKEAVATLEKEHSAELERL-CSSLEAKH-REVVSSLQKKIQ-EAQQKEEAQLQKCLGQVE 815
Query: 166 SSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEV 225
+ V+ G E L +L+RE+ E E K +E Q+V
Sbjct: 816 HRVHQKSYHVA-GYEHELS-------------SLLREKRQEVEGEHERRLDKMKEEHQQV 861
Query: 226 LEMRKIVAEYE--------KTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN----S 273
M K +YE + + + + +R ++ + + E+ + L DL
Sbjct: 862 --MAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHRE 919
Query: 274 VERSLSDLF----RRYENLKGVLEGFKKNEEALKKCAQDYL-----ARVKQEE------Q 318
ER L DL R +++K L + EE ++ Q L +K EE Q
Sbjct: 920 QERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQ 979
Query: 319 RYQALKIH-----AEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQK 373
+A K H + ++L + +E+ + K +++ L A ++ Q SLE Q+K
Sbjct: 980 LEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKK 1039
Query: 374 NQEIEELT 381
+ E+T
Sbjct: 1040 QHLLREVT 1047
Score = 29.6 bits (65), Expect = 5.0
Identities = 32/171 (18%), Positives = 71/171 (41%), Gaps = 16/171 (9%)
Query: 213 EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALA--- 269
E + K + R +LE+++ A EK Q + D QR Q+ ++ E+A A
Sbjct: 932 ETRAKDVKARLALLEVQEETARREK---QQLLDVQR----------QVALKSEEATATHQ 978
Query: 270 DLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEE 329
L ++ + L + + L+ +L+ + + L+ A+ +Q ++ + +L+ A++
Sbjct: 979 QLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQK 1038
Query: 330 KLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 380
K E + + LH ++ + + +Q E+L
Sbjct: 1039 KQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDL 1089
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 52.8 bits (125), Expect = 5e-07
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 200 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 259
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 757 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 812
Query: 260 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 316
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 813 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 872
Query: 317 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 374
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 873 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 932
Query: 375 QEIEELTKICDELIA 389
++ E K E+I+
Sbjct: 933 NQLAECKKQHQEVIS 947
Score = 43.1 bits (100), Expect = 4e-04
Identities = 56/251 (22%), Positives = 114/251 (45%), Gaps = 33/251 (13%)
Query: 151 QKMEEDGSTVLGLLESS-AEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEI 209
Q+++E + LESS AE+ + V + +CL+ ++ I E
Sbjct: 435 QQLQEILQDLQKRLESSEAERKQLQVELQSRRA-ELVCLNNTE-------ISENSSDLSQ 486
Query: 210 EANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALA 269
+ E + KYEE +EVL ++K + ++ E SM + F +L + +E+
Sbjct: 487 KLKETQSKYEEAMKEVLSVQK------QMKLGLVSPE---SMDNYSHFHELRVTEEEINV 537
Query: 270 DLNSVERSLSDLFRRYENLKGVLEGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL---- 323
++ +L + R E ++ + E + E+ +K ++Y ++ + Y ++
Sbjct: 538 LKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENM 593
Query: 324 ---KIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 380
K EK +A EEI +++ K++ A E MK E++ R + + N+++ EL
Sbjct: 594 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSEL 651
Query: 381 TKICDELIAKL 391
+++ E A+L
Sbjct: 652 SQLYKEAQAEL 662
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 192 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 251
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 837 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 888
Query: 252 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 311
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 889 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 939
Query: 312 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 349
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 940 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 980
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 52.8 bits (125), Expect = 5e-07
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 200 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 259
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 746 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 801
Query: 260 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 316
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 802 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 861
Query: 317 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 374
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 862 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 921
Query: 375 QEIEELTKICDELIA 389
++ E K E+I+
Sbjct: 922 NQLAECKKQHQEVIS 936
Score = 43.1 bits (100), Expect = 4e-04
Identities = 56/251 (22%), Positives = 114/251 (45%), Gaps = 33/251 (13%)
Query: 151 QKMEEDGSTVLGLLESS-AEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEI 209
Q+++E + LESS AE+ + V + +CL+ ++ I E
Sbjct: 424 QQLQEILQDLQKRLESSEAERKQLQVELQSRRA-ELVCLNNTE-------ISENSSDLSQ 475
Query: 210 EANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALA 269
+ E + KYEE +EVL ++K + ++ E SM + F +L + +E+
Sbjct: 476 KLKETQSKYEEAMKEVLSVQK------QMKLGLVSPE---SMDNYSHFHELRVTEEEINV 526
Query: 270 DLNSVERSLSDLFRRYENLKGVLEGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL---- 323
++ +L + R E ++ + E + E+ +K ++Y ++ + Y ++
Sbjct: 527 LKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENM 582
Query: 324 ---KIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 380
K EK +A EEI +++ K++ A E MK E++ R + + N+++ EL
Sbjct: 583 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSEL 640
Query: 381 TKICDELIAKL 391
+++ E A+L
Sbjct: 641 SQLYKEAQAEL 651
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 192 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 251
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 826 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 877
Query: 252 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 311
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 878 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 928
Query: 312 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 349
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 929 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 969
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 52.8 bits (125), Expect = 5e-07
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 200 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 259
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 725 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 780
Query: 260 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 316
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 781 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 840
Query: 317 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 374
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 841 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 900
Query: 375 QEIEELTKICDELIA 389
++ E K E+I+
Sbjct: 901 NQLAECKKQHQEVIS 915
Score = 43.1 bits (100), Expect = 4e-04
Identities = 56/251 (22%), Positives = 114/251 (45%), Gaps = 33/251 (13%)
Query: 151 QKMEEDGSTVLGLLESS-AEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEI 209
Q+++E + LESS AE+ + V + +CL+ ++ I E
Sbjct: 403 QQLQEILQDLQKRLESSEAERKQLQVELQSRRA-ELVCLNNTE-------ISENSSDLSQ 454
Query: 210 EANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALA 269
+ E + KYEE +EVL ++K + ++ E SM + F +L + +E+
Sbjct: 455 KLKETQSKYEEAMKEVLSVQK------QMKLGLVSPE---SMDNYSHFHELRVTEEEINV 505
Query: 270 DLNSVERSLSDLFRRYENLKGVLEGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL---- 323
++ +L + R E ++ + E + E+ +K ++Y ++ + Y ++
Sbjct: 506 LKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENM 561
Query: 324 ---KIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 380
K EK +A EEI +++ K++ A E MK E++ R + + N+++ EL
Sbjct: 562 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSEL 619
Query: 381 TKICDELIAKL 391
+++ E A+L
Sbjct: 620 SQLYKEAQAEL 630
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 192 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 251
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 805 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 856
Query: 252 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 311
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 857 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 907
Query: 312 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 349
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 908 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 948
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 52.8 bits (125), Expect = 5e-07
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 200 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 259
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 754 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 809
Query: 260 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 316
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 810 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 869
Query: 317 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 374
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 870 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 929
Query: 375 QEIEELTKICDELIA 389
++ E K E+I+
Sbjct: 930 NQLAECKKQHQEVIS 944
Score = 43.1 bits (100), Expect = 4e-04
Identities = 56/251 (22%), Positives = 114/251 (45%), Gaps = 33/251 (13%)
Query: 151 QKMEEDGSTVLGLLESS-AEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEI 209
Q+++E + LESS AE+ + V + +CL+ ++ I E
Sbjct: 432 QQLQEILQDLQKRLESSEAERKQLQVELQSRRA-ELVCLNNTE-------ISENSSDLSQ 483
Query: 210 EANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALA 269
+ E + KYEE +EVL ++K + ++ E SM + F +L + +E+
Sbjct: 484 KLKETQSKYEEAMKEVLSVQK------QMKLGLVSPE---SMDNYSHFHELRVTEEEINV 534
Query: 270 DLNSVERSLSDLFRRYENLKGVLEGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL---- 323
++ +L + R E ++ + E + E+ +K ++Y ++ + Y ++
Sbjct: 535 LKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENM 590
Query: 324 ---KIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 380
K EK +A EEI +++ K++ A E MK E++ R + + N+++ EL
Sbjct: 591 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSEL 648
Query: 381 TKICDELIAKL 391
+++ E A+L
Sbjct: 649 SQLYKEAQAEL 659
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 192 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 251
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 834 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 885
Query: 252 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 311
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 886 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 936
Query: 312 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 349
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 937 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 977
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 52.8 bits (125), Expect = 5e-07
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 200 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 259
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 754 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 809
Query: 260 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 316
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 810 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 869
Query: 317 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 374
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 870 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 929
Query: 375 QEIEELTKICDELIA 389
++ E K E+I+
Sbjct: 930 NQLAECKKQHQEVIS 944
Score = 43.1 bits (100), Expect = 4e-04
Identities = 56/251 (22%), Positives = 114/251 (45%), Gaps = 33/251 (13%)
Query: 151 QKMEEDGSTVLGLLESS-AEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEI 209
Q+++E + LESS AE+ + V + +CL+ ++ I E
Sbjct: 432 QQLQEILQDLQKRLESSEAERKQLQVELQSRRA-ELVCLNNTE-------ISENSSDLSQ 483
Query: 210 EANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALA 269
+ E + KYEE +EVL ++K + ++ E SM + F +L + +E+
Sbjct: 484 KLKETQSKYEEAMKEVLSVQK------QMKLGLVSPE---SMDNYSHFHELRVTEEEINV 534
Query: 270 DLNSVERSLSDLFRRYENLKGVLEGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL---- 323
++ +L + R E ++ + E + E+ +K ++Y ++ + Y ++
Sbjct: 535 LKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENM 590
Query: 324 ---KIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 380
K EK +A EEI +++ K++ A E MK E++ R + + N+++ EL
Sbjct: 591 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSEL 648
Query: 381 TKICDELIAKL 391
+++ E A+L
Sbjct: 649 SQLYKEAQAEL 659
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 192 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 251
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 834 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 885
Query: 252 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 311
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 886 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 936
Query: 312 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 349
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 937 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 977
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 52.8 bits (125), Expect = 5e-07
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 200 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 259
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 754 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 809
Query: 260 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 316
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 810 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 869
Query: 317 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 374
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 870 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 929
Query: 375 QEIEELTKICDELIA 389
++ E K E+I+
Sbjct: 930 NQLAECKKQHQEVIS 944
Score = 43.1 bits (100), Expect = 4e-04
Identities = 56/251 (22%), Positives = 114/251 (45%), Gaps = 33/251 (13%)
Query: 151 QKMEEDGSTVLGLLESS-AEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEI 209
Q+++E + LESS AE+ + V + +CL+ ++ I E
Sbjct: 432 QQLQEILQDLQKRLESSEAERKQLQVELQSRRA-ELVCLNNTE-------ISENSSDLSQ 483
Query: 210 EANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALA 269
+ E + KYEE +EVL ++K + ++ E SM + F +L + +E+
Sbjct: 484 KLKETQSKYEEAMKEVLSVQK------QMKLGLVSPE---SMDNYSHFHELRVTEEEINV 534
Query: 270 DLNSVERSLSDLFRRYENLKGVLEGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL---- 323
++ +L + R E ++ + E + E+ +K ++Y ++ + Y ++
Sbjct: 535 LKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENM 590
Query: 324 ---KIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 380
K EK +A EEI +++ K++ A E MK E++ R + + N+++ EL
Sbjct: 591 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSEL 648
Query: 381 TKICDELIAKL 391
+++ E A+L
Sbjct: 649 SQLYKEAQAEL 659
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 192 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 251
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 834 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 885
Query: 252 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 311
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 886 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 936
Query: 312 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 349
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 937 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 977
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 52.4 bits (124), Expect = 7e-07
Identities = 89/412 (21%), Positives = 180/412 (43%), Gaps = 76/412 (18%)
Query: 29 EDEAGGPEGDPEEEDSQAETKSLSFRSGCKVKKHETQSLALDAC---------------- 72
++E + E+ + E KSL F+ K E ++ LD C
Sbjct: 1182 DEEFQSLKSSHEKSNKSLEDKSLEFK-----KLSEELAIQLDICCKKTEALLEAKTNELI 1236
Query: 73 ---SRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNV 129
S A++S+IS +R +E L +C A+++ EE
Sbjct: 1237 NISSSKTNAILSRISHCQHRTTKV--KEALLIKTCTVSELEAQLRQLTEEQ--------- 1285
Query: 130 PVSTINHAFSSSEAGIEKETCQ--KMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGIC 187
+T+N +F + +E++ Q M+ D +++ E+ ++ E C
Sbjct: 1286 --NTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKES---C 1340
Query: 188 LSE-----SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQM 242
+++ S+ +TL++EE+ K++E + K+ + + L+ ++E E I+ +
Sbjct: 1341 ITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQ-LQNSISLSEKEAAISSL 1399
Query: 243 IE--DEQRTSMTSQK---SFQQLTMEKEQ--ALADLNSVERSLSDL-------FRRYEN- 287
+ DE++ + Q SF+ T+ KE+ AL ++ S+ F +++N
Sbjct: 1400 RKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNT 1459
Query: 288 ---LKGVLEGFKKNEEALKKCAQDYLAR--VKQEEQRYQALKIHAEEKLDKANEEIAQVR 342
L+ LE K++EA +K Q L + + Q+ +R+ LK E+ K ++ + +
Sbjct: 1460 VKELQIQLE--LKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLE 1517
Query: 343 TKAKAESAA---LHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKL 391
T+ K+++A L + ++ +++ESL L+ NQ+ + K EL+ KL
Sbjct: 1518 TELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHK---ELVQKL 1566
Score = 51.2 bits (121), Expect = 2e-06
Identities = 67/325 (20%), Positives = 147/325 (45%), Gaps = 35/325 (10%)
Query: 69 LDACSRDEGAVISQISDISNRDGHATDEE--KLASTSCGQKSAGAEVKGEPEEDLEYFEC 126
++ +D+G VI++ + +EE +L S + G E++ + E+
Sbjct: 355 IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKS------ 408
Query: 127 SNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSV----SCGGESP 182
+ A S+++ +E +K++ + + +E ++E+ +S+ S +
Sbjct: 409 ERAAFEELEKALSTAQK--TEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEV 466
Query: 183 LDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQM 242
+D + S ++ A L + E+ + ++ + E KK + +E E K+ E K+ ++
Sbjct: 467 VDVMKKSSEEQIAKLQKLHEKELARKEQ--ELTKKLQTREREFQEQMKVALE--KSQSEY 522
Query: 243 IEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKG-VLEGFKKNEEA 301
++ Q + ++L ++K+ A L E L DL + E + +LE E +
Sbjct: 523 LKISQEKEQQESLALEELELQKK---AILTESENKLRDLQQEAETYRTRILE----LESS 575
Query: 302 LKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQM 361
L+K Q+ + + + L +H E + +K N+EI + K K E +L +++ +
Sbjct: 576 LEKSLQE-------NKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKH--QQDAL 626
Query: 362 KVESLERALQQKNQEIEELTKICDE 386
E L+ QQ E+E+L + C++
Sbjct: 627 WTEKLQVLKQQYQTEMEKLREKCEQ 651
Score = 46.6 bits (109), Expect = 4e-05
Identities = 51/208 (24%), Positives = 94/208 (45%), Gaps = 18/208 (8%)
Query: 188 LSESDKTAVLTLIRE-EIITKEIEANEWKKKYEETRQ--EVLEMRKI-VAEYEKTIAQMI 243
L ++KT ++T +R+ + + +++E ++ E RQ E LEM++ +A+ I QM
Sbjct: 336 LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMT 395
Query: 244 EDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALK 303
+ +KS + E E+AL+ E + L + +E K E +
Sbjct: 396 TQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIE---KTSEEER 452
Query: 304 KCAQDYLARVKQE----------EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH 353
Q L+RVKQE EQ + K+H +E K E +++T+ + +
Sbjct: 453 ISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK 512
Query: 354 AGLRKEQMK-VESLERALQQKNQEIEEL 380
L K Q + ++ + QQ++ +EEL
Sbjct: 513 VALEKSQSEYLKISQEKEQQESLALEEL 540
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/129 (29%), Positives = 62/129 (48%), Gaps = 8/129 (6%)
Query: 261 TMEKEQALADLNSVERSLSDLFRRYENL---KGVLEGFKKNEEALKKCAQD----YLARV 313
++ KEQ + L +ERSLS +Y L +L+ KK + + +QD +A +
Sbjct: 133 SLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAEL 192
Query: 314 KQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQK 373
++E Q Q K H +E+ D + EE Q + + + + L LR M V+ L + L Q
Sbjct: 193 REELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVL-KPLPQL 251
Query: 374 NQEIEELTK 382
+ E TK
Sbjct: 252 EPQAEVFTK 260
Score = 43.1 bits (100), Expect = 4e-04
Identities = 43/185 (23%), Positives = 88/185 (47%), Gaps = 23/185 (12%)
Query: 214 WKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNS 273
++ K E+ +E + ++I+ E E I QM E ++ K + LT + ++
Sbjct: 888 YESKLEDGNKEQEQTKQILVEKENMILQMREGQK-------KEIEILTQKLSAKEDSIHI 940
Query: 274 VERSLSDLFRRYEN-LKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD 332
+ F+ E ++ V + K+ +E LKK D A++K+E + AL++ +EK
Sbjct: 941 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELEN-TALELSQKEKQF 999
Query: 333 KA-------------NEEIAQVRTKAKAESAALHAGLRKEQMKVESL-ERALQQKNQEIE 378
A ++ ++++ T K + +L R+E V S+ E+ L Q+ +E++
Sbjct: 1000 NAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQ 1059
Query: 379 ELTKI 383
E+ +I
Sbjct: 1060 EIHEI 1064
Score = 40.0 bits (92), Expect = 0.004
Identities = 79/370 (21%), Positives = 155/370 (41%), Gaps = 40/370 (10%)
Query: 42 EDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEGAVISQISD-ISNRDGHATDEEKLA 100
E SQ+ET + RS V + Q A +G V + IS + T++EKL
Sbjct: 1699 ESSQSETLIVP-RSAKNVAAYTEQEEA-----DSQGCVQKTYEEKISVLQRNLTEKEKLL 1752
Query: 101 STSCGQK----SAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEED 156
+K S+ E++ + +E L E + H S +++E +K ++
Sbjct: 1753 QRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAK----QHEDQSMIGHLQEELEEKNKKY 1808
Query: 157 GSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKK 216
V +E K + E+ D + + +K ++ ++I KE+++ ++
Sbjct: 1809 SLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKI--KELDSCLVRQ 1866
Query: 217 KYEETRQEVLEMRKIVAEYEK--TIAQMIEDEQRTSM----TSQKSFQQLTMEK--EQAL 268
K +EM ++ ++YEK + QM + T + T +KS L K
Sbjct: 1867 KEVHR----VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNME 1922
Query: 269 ADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQE--EQRYQALKIH 326
A N +E L+ R + L + +K+ L+K Q L +K+E ++R + +K
Sbjct: 1923 AQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQE 1982
Query: 327 AEEKLDKANEEIAQVRTKAKAESAALHAGL---------RKEQMKVESLERALQQKNQEI 377
E+ K N + Q+ + + A L + ++++ E LE ++ NQ +
Sbjct: 1983 QEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLL 2042
Query: 378 EELTKICDEL 387
+++ + D+L
Sbjct: 2043 KKIAEKDDDL 2052
Score = 33.5 bits (75), Expect = 0.34
Identities = 57/297 (19%), Positives = 111/297 (37%), Gaps = 47/297 (15%)
Query: 113 VKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKM-------EEDGSTVLGLLE 165
+K E E + E N+ V + + E +E E+ K+ E+ + + L
Sbjct: 1597 MKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLL 1656
Query: 166 SSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEW-------KKKY 218
S E+ G ES L + ++ + ++ E++ + E +E K
Sbjct: 1657 SQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVA 1716
Query: 219 EETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSL 278
T QE + + V +KT + I QR +K Q++ EKE+ ++ +
Sbjct: 1717 AYTEQEEADSQGCV---QKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQY 1773
Query: 279 SDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEI 338
+ + E+ A KQ E Q++ H +E+L++ N++
Sbjct: 1774 QERLIKLEH-----------------------AEAKQHED--QSMIGHLQEELEEKNKKY 1808
Query: 339 AQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 395
+ + A+ G Q K ++LE + ++E C L K+ + D
Sbjct: 1809 SLI----VAQHVEKEGGKNNIQAK-QNLENVFDDVQKTLQEKELTCQILEQKIKELD 1860
Score = 33.1 bits (74), Expect = 0.45
Identities = 43/190 (22%), Positives = 74/190 (38%), Gaps = 31/190 (16%)
Query: 209 IEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQAL 268
+E N+ ++ T E+ +++ +EK + Q E+ Q+ + EKEQ +
Sbjct: 1021 LETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEE-------LQEIHEIQLQEKEQEV 1073
Query: 269 ADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAE 328
A+L K +L G +K E + +K+E + +
Sbjct: 1074 AELKQ---------------KILLFGCEKEE------MNKEITWLKEEGVKQDTTLNELQ 1112
Query: 329 EKLDKAN---EEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICD 385
E+L + + +AQ TK KA L L K + L+ L + EE +
Sbjct: 1113 EQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVS 1172
Query: 386 ELIAKLGKTD 395
EL +KL TD
Sbjct: 1173 ELTSKLKTTD 1182
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 51.2 bits (121), Expect = 2e-06
Identities = 68/337 (20%), Positives = 127/337 (37%), Gaps = 27/337 (8%)
Query: 29 EDEAGGPEGDPEEEDSQAETKSLSFRSG-CKVKKHETQSLALDACSRD-EGAVISQISDI 86
E + EG E++ Q + R +V++ E Q + R+ EG V Q +
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
Query: 87 SNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIE 146
++G ++E GQ E GE EE ++ E + G +
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE---------------EQMGEQ 225
Query: 147 KETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIIT 206
+E +K EE +G E +K V E + + +EE +
Sbjct: 226 EEQMRKQEEQ----MGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE--QEEQML 279
Query: 207 KEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQ 266
K+ E E +++ E +++ E + + E E+ + + E + K +Q+ +KEQ
Sbjct: 280 KQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ 339
Query: 267 ALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARV----KQEEQRYQA 322
+ + + + E ++ E +K EE ++K + + KQEEQ +
Sbjct: 340 MWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ 399
Query: 323 LKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKE 359
+ E+K +E K + H G +KE
Sbjct: 400 KEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/196 (28%), Positives = 91/196 (46%), Gaps = 24/196 (12%)
Query: 201 REEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT----------IAQMIEDEQRTS 250
R++++ E++ ++ K QE EM +A E + Q IE+ + T+
Sbjct: 293 RQKLLKLEVD---FEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETN 349
Query: 251 MTSQKSFQQLTMEKEQALAD-LNSVERSLSDLFRRYENL-KGVLEGFKKNEEALKKCAQD 308
QK+ ++L Q L D + E S L ENL K VLE K+EE K +Q
Sbjct: 350 KNLQKAEEEL-----QELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQC 404
Query: 309 YLARVKQEEQRYQALKIHAE-EKLDKANEEIAQVR---TKAKAESAALHAGLRKEQMKVE 364
R K +E+ + + ++ E EKL K E+ ++ +K+K+E LH L KE+ +
Sbjct: 405 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 464
Query: 365 SLERALQQKNQEIEEL 380
L L+ ++EL
Sbjct: 465 DLLNELEVVKSRVKEL 480
Score = 42.7 bits (99), Expect = 6e-04
Identities = 64/291 (21%), Positives = 130/291 (44%), Gaps = 55/291 (18%)
Query: 139 SSSEAGIEKETCQKMEED---GSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTA 195
S SE +K+ + E+D TV L++S E C ++ + LS+ D
Sbjct: 31 SLSEDAKKKKKSNRKEDDVMASGTVKRHLKTSGE-------CERKTK-KSLELSKEDLIQ 82
Query: 196 VLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAE--------------------- 234
+L+++ E+ +E + K E+T+ EVLE AE
Sbjct: 83 LLSIMEGELQAREDVIHMLKT--EKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIG 140
Query: 235 ---YEKTIAQMIEDEQRTSMTSQKSFQQLTMEKE---QALADLNSVERSLSDLFRRYENL 288
YEK I+++ E++ T ++ +QL + ++ + + +L + + +D + ++
Sbjct: 141 EDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDF 200
Query: 289 KGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEK-LDKANEEIAQVRTKA-- 345
+LE + E LKK + ++E+ YQA K K L+K +E+ ++++ A
Sbjct: 201 TNLLE---QERERLKK--------LLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALM 249
Query: 346 KAESAALH-AGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 395
+ +H L + KV+ L + L+++ ++++ +T E KL K +
Sbjct: 250 LVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLE 300
Score = 37.7 bits (86), Expect = 0.018
Identities = 53/238 (22%), Positives = 96/238 (40%), Gaps = 48/238 (20%)
Query: 202 EEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQ-QL 260
EEI E + E +KK +E E+R V + +K ++++ + E+ S + + Q L
Sbjct: 395 EEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHL 454
Query: 261 TMEKEQALAD----------------------LNSVERSLSDLFRRYENLKGVL------ 292
+EKE+ L L E SL D + ++ +L
Sbjct: 455 NLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKN 514
Query: 293 ------------EGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQ 340
+G KN + + D ++ +E ++ LK EEK+ E +
Sbjct: 515 MMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDE 574
Query: 341 VRTKAKAE---SAALHAG---LRKEQMKVESLERALQQ-KNQEIEELTKICDELIAKL 391
+ K K+E S+ L L+K +E +ER + + ++++ ELT D I +L
Sbjct: 575 LIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKEL 632
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 51.2 bits (121), Expect = 2e-06
Identities = 58/210 (27%), Positives = 96/210 (45%), Gaps = 26/210 (12%)
Query: 198 TLIREEIITKEIEANEWKKKYEE----TRQEVL-------EMRKIVAEYEKTIAQMIEDE 246
TL R IT+E W+ +E +R EV+ + K + + ED+
Sbjct: 188 TLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDK 247
Query: 247 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA 306
T+++S +++ EK + + L+ VERSLS+ +LK + E + +E L++ A
Sbjct: 248 HNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNE---RTQEELRELA 304
Query: 307 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESL 366
Y V + + LK+ AE K EEI Q K +AE L + + + K + L
Sbjct: 305 NKYNGAVNEIKDLSDKLKV-AEGK----QEEIQQ---KGQAEKKELQHKIDEMEEKEQEL 356
Query: 367 E---RALQQKNQ-EIEELTKICDELIAKLG 392
+ ALQ N E LT + + L++K G
Sbjct: 357 QAKIEALQADNDFTNERLTALQEHLLSKSG 386
Score = 36.2 bits (82), Expect = 0.053
Identities = 40/202 (19%), Positives = 85/202 (42%), Gaps = 20/202 (9%)
Query: 191 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTS 250
S++ + ++EE+ E W+K E +E+ ++ + Q ED+QR
Sbjct: 579 SERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNSF----QLRCQQCEDQQREE 634
Query: 251 MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKK-----NEEALKKC 305
T +L E E+ + N++E L R L L+ +K +++L+
Sbjct: 635 AT------RLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELT 688
Query: 306 AQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVES 365
+ + ++ ++E Q + + D A ++ + +KA+ ++ + K Q +
Sbjct: 689 SDLSILQMSRKELENQVGSLKEQHLRDSA--DLKTLLSKAENQAKDVQKEYEKTQTVLSE 746
Query: 366 LERALQQKNQEIEELTKICDEL 387
L+ + QE + +T DEL
Sbjct: 747 LKLKFEMTEQEKQSIT---DEL 765
Score = 32.7 bits (73), Expect = 0.59
Identities = 31/141 (21%), Positives = 55/141 (39%), Gaps = 7/141 (4%)
Query: 197 LTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKS 256
L +R+E E E + K++ E+ K + +K ++ D M+ ++
Sbjct: 642 LEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKEL 701
Query: 257 FQQLTMEKEQALAD-------LNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDY 309
Q+ KEQ L D L+ E D+ + YE + VL K E ++ Q
Sbjct: 702 ENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSI 761
Query: 310 LARVKQEEQRYQALKIHAEEK 330
+KQ + + L+ K
Sbjct: 762 TDELKQCKNNLKLLREKGNNK 782
Score = 32.3 bits (72), Expect = 0.76
Identities = 38/204 (18%), Positives = 86/204 (42%), Gaps = 26/204 (12%)
Query: 197 LTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKS 256
LT ++E +++K + ++ E +++++ + E+T + E +T
Sbjct: 374 LTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEET---KLSKENQTRAKESDF 430
Query: 257 FQQLTMEKEQALADLNSV---ERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARV 313
L+ KE++ D E+ L++ + LK L+G + EA
Sbjct: 431 SDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEA------------ 478
Query: 314 KQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQ- 372
KQE Q + I A+E + ++ +++ + E A + + +++ L+ LQ+
Sbjct: 479 KQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRL 538
Query: 373 -------KNQEIEELTKICDELIA 389
+ ++ E+T DEL++
Sbjct: 539 HIDTENLREEKDSEITSTRDELLS 562
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 50.8 bits (120), Expect = 2e-06
Identities = 54/226 (23%), Positives = 107/226 (47%), Gaps = 30/226 (13%)
Query: 184 DGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQM- 242
D CL D+ A L ++ ++ A E K + QE+ +R +YE+ +
Sbjct: 1496 DRKCLE--DENARLQRVQYDLQKANSSATETINKLKVQEQELTRLR---IDYERVSQERT 1550
Query: 243 IEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN--EE 300
++D+ T Q S ++L ++K++ +LN ++R+ S+ + + L+ LEG +++ E+
Sbjct: 1551 VKDQDITRF--QNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ 1608
Query: 301 ALK------KCAQDYLARVKQEE---QRYQALKIHAEEKLDKANEEIAQVRTKAKA---- 347
A+K + Q + + + E+ Q+ L H EK + EE+ ++ ++ +A
Sbjct: 1609 AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREK-QRTQEELRRLSSEVEALRRQ 1667
Query: 348 ----ESAALHAGLRKE--QMKVESLERALQQKNQEIEELTKICDEL 387
+ + A LR E Q +E R+L + EIE L + + L
Sbjct: 1668 LLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENL 1713
Score = 46.2 bits (108), Expect = 5e-05
Identities = 40/182 (21%), Positives = 85/182 (46%), Gaps = 16/182 (8%)
Query: 207 KEIEA--NEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEK 264
KEIE E++++ + + E+ K+ Y++ I + + ++ + QLTM+K
Sbjct: 1325 KEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQK 1384
Query: 265 EQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALK 324
E+ D + + +L R +L E K+ + L + ++ L RV+++ Q+ +A
Sbjct: 1385 EE---DTSGYRAQIDNLTRENRSLS---EEIKRLKNTLTQTTEN-LRRVEEDIQQQKATG 1437
Query: 325 IHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKIC 384
++ + E+ QV ES + + ++ + +Q KN+EIE L ++
Sbjct: 1438 SEVSQRKQQLEVELRQVTQMRTEESV-------RYKQSLDDAAKTIQDKNKEIERLKQLI 1490
Query: 385 DE 386
D+
Sbjct: 1491 DK 1492
Score = 35.8 bits (81), Expect = 0.069
Identities = 34/166 (20%), Positives = 73/166 (43%), Gaps = 20/166 (12%)
Query: 215 KKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSV 274
K++YE E+ K+ Y + ++ + + ++ + ++++M+KE D ++
Sbjct: 1185 KREYEN------ELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKED---DSKNL 1235
Query: 275 ERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKA 334
L L R +LK E + N+ L+ A + R ++ + +A +K
Sbjct: 1236 RNQLDRLSRENRDLKD--EIVRLNDSILQ--ATEQRRRAEENALQQKACGSEIMQKKQHL 1291
Query: 335 NEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 380
E+ QV + ++A + + +E + +Q KN+EIE L
Sbjct: 1292 EIELKQVMQQRSEDNA-------RHKQSLEEAAKTIQDKNKEIERL 1330
Score = 33.5 bits (75), Expect = 0.34
Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 21/191 (10%)
Query: 200 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 259
+ EE+ + A+E K ++ +E+ MR+ + E I + + ++ S+ ++S
Sbjct: 1573 VEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDD 1632
Query: 260 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQR 319
L +++ L +R+ +L R EAL++ VKQ R
Sbjct: 1633 LRQQRDVLDGHLREKQRTQEELRR-----------LSSEVEALRRQLLQEQESVKQAHLR 1681
Query: 320 YQALKIHAEEKLDKANE---EIAQVRTKAK---AESAALHAGLRKEQMKVESLER----A 369
+ + E+K NE EI ++++ + E L LR +++ + L R A
Sbjct: 1682 NEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEA 1741
Query: 370 LQQKNQEIEEL 380
KN I EL
Sbjct: 1742 DSDKNATILEL 1752
Score = 33.5 bits (75), Expect = 0.34
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 22/170 (12%)
Query: 227 EMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYE 286
E+R + EY+ E + + T + QL + + L ++ ++DL R E
Sbjct: 1723 ELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTL----ELQGLINDLQRERE 1778
Query: 287 NLKGVLEGFKKN--------EEALKKCAQ------DYLARVKQEEQRYQALKIHAEEKLD 332
NL+ +E F+K +E+ +C Q L ++K EQ L+ E++L+
Sbjct: 1779 NLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQ-RLEDELN 1837
Query: 333 KAN---EEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEE 379
+A E +V+ + + E + L + + + E A+++ E E+
Sbjct: 1838 RAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREK 1887
Score = 33.5 bits (75), Expect = 0.34
Identities = 42/194 (21%), Positives = 86/194 (44%), Gaps = 44/194 (22%)
Query: 200 IREEIITKEIEANEWKKKYEETR---------QEVLEMRKIVAEYEKTIAQMIEDE---- 246
+R+EI + +A E + +E++ +E L ++ V E +K Q +EDE
Sbjct: 1780 LRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRA 1839
Query: 247 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA 306
+ T + Q+L EK+Q DLN + + + EEA++K
Sbjct: 1840 KSTLEAETRVKQRLECEKQQIQNDLNQWKTQ-----------------YSRKEEAIRK-- 1880
Query: 307 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESL 366
++ E ++ + K ++++ EI ++ + + + L R+ Q ++E+
Sbjct: 1881 ------IESEREKSEREKNSLRSEIERLQAEIKRIEERCRRK---LEDSTRETQSQLET- 1930
Query: 367 ERALQQKNQEIEEL 380
ER+ Q+ EI++L
Sbjct: 1931 ERSRYQR--EIDKL 1942
Score = 30.4 bits (67), Expect = 2.9
Identities = 34/166 (20%), Positives = 75/166 (45%), Gaps = 8/166 (4%)
Query: 216 KKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADL-NSV 274
+K + +E L +K+ E EK I + + +R + Q+ + E E LA + N
Sbjct: 1143 QKARQCEKENLGWQKL--ESEKAIKEKEYEIERLRVLLQEEGTR-KREYENELAKVRNHY 1199
Query: 275 ERSLSDLFRRYEN----LKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEK 330
+S+L +YE K ++ +E K ++ L R+ +E + + + +
Sbjct: 1200 NEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDS 1259
Query: 331 LDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQE 376
+ +A E+ + A + A ++K+Q L++ +QQ++++
Sbjct: 1260 ILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSED 1305
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 50.4 bits (119), Expect = 3e-06
Identities = 74/375 (19%), Positives = 147/375 (39%), Gaps = 39/375 (10%)
Query: 38 DPEEEDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEE 97
+ +E ++E K + G K E L+ + C A G T +
Sbjct: 370 EEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAA----------GRLTQQR 419
Query: 98 KLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIE-KETCQKMEED 156
K+ T Q K + E D + N + +N + + +E KE K E +
Sbjct: 420 KIGKTYPQQFPK----KLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVE 475
Query: 157 GSTVLGLLESSAEKAPVSVSCGG---------ESPLDGICLSESDKTAVLTLIREEIITK 207
+ ++S K+ + + + +D C+ ++D + ++R+EI T
Sbjct: 476 AKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKAD----IAILRQEICTM 531
Query: 208 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA 267
+ + E + KY + + V E + +Y K +MI + T+ Q+ L E +
Sbjct: 532 KNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE---TAFRYQQELNDLKAENTRL 588
Query: 268 LADLNSVERSLSDLFRRYENLKGVL-EGFKKNEEALKKCAQDYLARVKQEEQRYQALKIH 326
A+L + S L E+ + L K+ E++K LA + + Q
Sbjct: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSS 648
Query: 327 AEEKLDKANEEIAQVRTKAKAESAAL-------HAGLRKEQMKVESLERALQQKNQEIEE 379
A K+ NE + + ++ + + AL LRK+ + +E+++ L Q Q+ +E
Sbjct: 649 AISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQE 708
Query: 380 LTKICDELIAKLGKT 394
+ ++ AK+ +
Sbjct: 709 MKEMYQNAEAKVNNS 723
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 50.4 bits (119), Expect = 3e-06
Identities = 74/375 (19%), Positives = 147/375 (39%), Gaps = 39/375 (10%)
Query: 38 DPEEEDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEE 97
+ +E ++E K + G K E L+ + C A G T +
Sbjct: 370 EEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAA----------GRLTQQR 419
Query: 98 KLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIE-KETCQKMEED 156
K+ T Q K + E D + N + +N + + +E KE K E +
Sbjct: 420 KIGKTYPQQFPK----KLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVE 475
Query: 157 GSTVLGLLESSAEKAPVSVSCGG---------ESPLDGICLSESDKTAVLTLIREEIITK 207
+ ++S K+ + + + +D C+ ++D + ++R+EI T
Sbjct: 476 AKQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKAD----IAILRQEICTM 531
Query: 208 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA 267
+ + E + KY + + V E + +Y K +MI + T+ Q+ L E +
Sbjct: 532 KNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE---TAFRYQQELNDLKAENTRL 588
Query: 268 LADLNSVERSLSDLFRRYENLKGVL-EGFKKNEEALKKCAQDYLARVKQEEQRYQALKIH 326
A+L + S L E+ + L K+ E++K LA + + Q
Sbjct: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSS 648
Query: 327 AEEKLDKANEEIAQVRTKAKAESAAL-------HAGLRKEQMKVESLERALQQKNQEIEE 379
A K+ NE + + ++ + + AL LRK+ + +E+++ L Q Q+ +E
Sbjct: 649 AISKVKAENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQE 708
Query: 380 LTKICDELIAKLGKT 394
+ ++ AK+ +
Sbjct: 709 MKEMYQNAEAKVNNS 723
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/187 (27%), Positives = 87/187 (46%), Gaps = 15/187 (8%)
Query: 205 ITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEK 264
+ + ++ E K Y E + + E+ I + YE+ Q I+D ++ + +E+
Sbjct: 684 LQERLKNQEKKIDYFERAKRLEEIPLIKSAYEE---QRIKDMDLWEQQEEERITTMQLER 740
Query: 265 EQALADLNSVERSLSDLFRRYENLKGVL-----EGFKKNEEALKKCAQDYLA---RVKQE 316
E+AL N + R L D LK E K+ EE L + + L R ++E
Sbjct: 741 EKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKE 800
Query: 317 EQRYQALKIHAEEKLDKANEEIAQVRT-KAKAESAALHAGLRKEQMKV---ESLERALQQ 372
E+R + EE+ +A E++ + R + +AE A LR+ Q +V E +ER +Q
Sbjct: 801 ERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQ 860
Query: 373 KNQEIEE 379
+ EIEE
Sbjct: 861 RELEIEE 867
Score = 39.3 bits (90), Expect = 0.006
Identities = 50/219 (22%), Positives = 96/219 (43%), Gaps = 41/219 (18%)
Query: 201 REEIITKEIEANEWKKKYEET-RQEVLEMRK--IVAEYE----KTIAQMIEDEQRTSMTS 253
+EE+ +E E + +K EE RQE E K I+ E+E KT+ + +E ++T + +
Sbjct: 591 KEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGA 650
Query: 254 Q--------------------KSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGV-L 292
+ K +QL EK++ L + E+ + D F R + L+ + L
Sbjct: 651 KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKI-DYFERAKRLEEIPL 709
Query: 293 EGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKAN--------EEIAQVRTK 344
E+ +K D +QEE+R +++ E+ L+ N ++ +R K
Sbjct: 710 IKSAYEEQRIK----DMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLK 765
Query: 345 AKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKI 383
A +S + E+ E L+++ ++ +E +I
Sbjct: 766 AARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRI 804
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 50.1 bits (118), Expect = 4e-06
Identities = 74/375 (19%), Positives = 147/375 (39%), Gaps = 39/375 (10%)
Query: 38 DPEEEDSQAETKSLSFRSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEE 97
+ +E ++E K + G K E L+ + C A G T +
Sbjct: 370 EEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAA----------GRLTQQR 419
Query: 98 KLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIE-KETCQKMEED 156
K+ T Q K + E D + N + +N + + +E KE K E +
Sbjct: 420 KIGKTYPQQFPK----KLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVE 475
Query: 157 GSTVLGLLESSAEKAPVSVSCGG---------ESPLDGICLSESDKTAVLTLIREEIITK 207
+ ++S K+ + + + +D C+ ++D + ++R+EI T
Sbjct: 476 AKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKAD----IAILRQEICTM 531
Query: 208 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA 267
+ + E + KY + + V E + +Y K +MI + T+ Q+ L E +
Sbjct: 532 KNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE---TAFRYQQELNYLKAENTRL 588
Query: 268 LADLNSVERSLSDLFRRYENLKGVL-EGFKKNEEALKKCAQDYLARVKQEEQRYQALKIH 326
A+L + S L E+ + L K+ E++K LA + + Q
Sbjct: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSS 648
Query: 327 AEEKLDKANEEIAQVRTKAKAESAAL-------HAGLRKEQMKVESLERALQQKNQEIEE 379
A K+ NE + + ++ + + AL LRK+ + +E+++ L Q Q+ +E
Sbjct: 649 AISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQE 708
Query: 380 LTKICDELIAKLGKT 394
+ ++ AK+ +
Sbjct: 709 MKEMYQNAEAKVNNS 723
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.336
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,292,052
Number of Sequences: 37866
Number of extensions: 641863
Number of successful extensions: 6138
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 143
Number of HSP's successfully gapped in prelim test: 707
Number of HSP's that attempted gapping in prelim test: 4139
Number of HSP's gapped (non-prelim): 2178
length of query: 395
length of database: 18,247,518
effective HSP length: 104
effective length of query: 291
effective length of database: 14,309,454
effective search space: 4164051114
effective search space used: 4164051114
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.