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Search of human proteins with 169658378
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
(2968 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 5944 0.0
gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens] 590 e-168
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 121 9e-27
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 109 4e-23
gi|55741677 SET domain containing 1A [Homo sapiens] 97 3e-19
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 89 5e-17
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 88 1e-16
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 87 2e-16
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 87 2e-16
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 86 5e-16
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 85 9e-16
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 85 9e-16
gi|161016767 mucin 21 [Homo sapiens] 85 1e-15
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 83 5e-15
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 82 1e-14
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 82 1e-14
gi|8923106 zinc finger, CCHC domain containing 10 [Homo sapiens] 81 1e-14
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-14
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens] 80 2e-14
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 80 2e-14
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 80 3e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni... 79 5e-14
gi|40807452 peroxisome proliferator-activated receptor gamma, co... 77 3e-13
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 76 4e-13
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 76 4e-13
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 76 4e-13
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 76 4e-13
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 76 4e-13
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 76 4e-13
gi|239755326 PREDICTED: hypothetical protein [Homo sapiens] 76 6e-13
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 5944 bits (15420), Expect = 0.0
Identities = 2968/2968 (100%), Positives = 2968/2968 (100%)
Query: 1 MDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHP 60
MDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHP
Sbjct: 1 MDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHP 60
Query: 61 HPGEAFLGSFVASGMGPSASSHGSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLP 120
HPGEAFLGSFVASGMGPSASSHGSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLP
Sbjct: 61 HPGEAFLGSFVASGMGPSASSHGSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLP 120
Query: 121 SGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHA 180
SGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHA
Sbjct: 121 SGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHA 180
Query: 181 PSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVD 240
PSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVD
Sbjct: 181 PSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVD 240
Query: 241 LTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEA 300
LTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEA
Sbjct: 241 LTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEA 300
Query: 301 GRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTVF 360
GRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTVF
Sbjct: 301 GRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTVF 360
Query: 361 REQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPL 420
REQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPL
Sbjct: 361 REQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPL 420
Query: 421 DRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPR 480
DRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPR
Sbjct: 421 DRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPR 480
Query: 481 GPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHHSRAEEEAA 540
GPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHHSRAEEEAA
Sbjct: 481 GPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHHSRAEEEAA 540
Query: 541 VVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAV 600
VVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAV
Sbjct: 541 VVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAV 600
Query: 601 AVRPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPES 660
AVRPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPES
Sbjct: 601 AVRPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPES 660
Query: 661 AKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLSLSNVKGHG 720
AKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLSLSNVKGHG
Sbjct: 661 AKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLSLSNVKGHG 720
Query: 721 RADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVT 780
RADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVT
Sbjct: 721 RADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVT 780
Query: 781 GGPALAGSGRWSADPAAHLATHPWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLG 840
GGPALAGSGRWSADPAAHLATHPWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLG
Sbjct: 781 GGPALAGSGRWSADPAAHLATHPWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLG 840
Query: 841 GSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSPLHHAQQLQ 900
GSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSPLHHAQQLQ
Sbjct: 841 GSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSPLHHAQQLQ 900
Query: 901 LFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGK 960
LFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGK
Sbjct: 901 LFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGK 960
Query: 961 AGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPA 1020
AGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPA
Sbjct: 961 AGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPA 1020
Query: 1021 YAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPP 1080
YAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPP
Sbjct: 1021 YAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPP 1080
Query: 1081 RYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKI 1140
RYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKI
Sbjct: 1081 RYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKI 1140
Query: 1141 TEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGL 1200
TEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGL
Sbjct: 1141 TEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGL 1200
Query: 1201 LEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEE 1260
LEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEE
Sbjct: 1201 LEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEE 1260
Query: 1261 PVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGST 1320
PVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGST
Sbjct: 1261 PVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGST 1320
Query: 1321 CFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLE 1380
CFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLE
Sbjct: 1321 CFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLE 1380
Query: 1381 QSFLHGITLLSEIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDP 1440
QSFLHGITLLSEIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDP
Sbjct: 1381 QSFLHGITLLSEIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDP 1440
Query: 1441 LKNLRLPRELKPNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQRE 1500
LKNLRLPRELKPNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQRE
Sbjct: 1441 LKNLRLPRELKPNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQRE 1500
Query: 1501 LVKLQRRRDSEDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLSSKSL 1560
LVKLQRRRDSEDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLSSKSL
Sbjct: 1501 LVKLQRRRDSEDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLSSKSL 1560
Query: 1561 LTSDDYELGAGIRKRHKGSEEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMA 1620
LTSDDYELGAGIRKRHKGSEEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMA
Sbjct: 1561 LTSDDYELGAGIRKRHKGSEEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMA 1620
Query: 1621 SDQEQLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKAL 1680
SDQEQLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKAL
Sbjct: 1621 SDQEQLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKAL 1680
Query: 1681 AKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEE 1740
AKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEE
Sbjct: 1681 AKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEE 1740
Query: 1741 FLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPF 1800
FLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPF
Sbjct: 1741 FLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPF 1800
Query: 1801 CLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGL 1860
CLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGL
Sbjct: 1801 CLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGL 1860
Query: 1861 EESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVK 1920
EESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVK
Sbjct: 1861 EESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVK 1920
Query: 1921 VRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEP 1980
VRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEP
Sbjct: 1921 VRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEP 1980
Query: 1981 GFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGR 2040
GFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGR
Sbjct: 1981 GFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGR 2040
Query: 2041 AKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKE 2100
AKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKE
Sbjct: 2041 AKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKE 2100
Query: 2101 NRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAPRSCIIDKDELK 2160
NRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAPRSCIIDKDELK
Sbjct: 2101 NRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAPRSCIIDKDELK 2160
Query: 2161 DGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPAS 2220
DGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPAS
Sbjct: 2161 DGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPAS 2220
Query: 2221 TRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLL 2280
TRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLL
Sbjct: 2221 TRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLL 2280
Query: 2281 PPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKA 2340
PPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKA
Sbjct: 2281 PPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKA 2340
Query: 2341 KGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAP 2400
KGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAP
Sbjct: 2341 KGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAP 2400
Query: 2401 PAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAEL 2460
PAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAEL
Sbjct: 2401 PAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAEL 2460
Query: 2461 LVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKA 2520
LVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKA
Sbjct: 2461 LVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKA 2520
Query: 2521 TDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSE 2580
TDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSE
Sbjct: 2521 TDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSE 2580
Query: 2581 TEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
TEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS
Sbjct: 2581 TEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 2641 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALP 2700
SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALP
Sbjct: 2641 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALP 2700
Query: 2701 TKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTT 2760
TKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTT
Sbjct: 2701 TKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTT 2760
Query: 2761 KELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIR 2820
KELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIR
Sbjct: 2761 KELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIR 2820
Query: 2821 IGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKQFHQGQHWDQK 2880
IGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKQFHQGQHWDQK
Sbjct: 2821 IGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKQFHQGQHWDQK 2880
Query: 2881 SSRSLPAALRVSSQRKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQD 2940
SSRSLPAALRVSSQRKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQD
Sbjct: 2881 SSRSLPAALRVSSQRKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQD 2940
Query: 2941 SEGLYYLAGTYEPTTGMIFSTDGVPVLC 2968
SEGLYYLAGTYEPTTGMIFSTDGVPVLC
Sbjct: 2941 SEGLYYLAGTYEPTTGMIFSTDGVPVLC 2968
>gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]
Length = 2608
Score = 590 bits (1521), Expect = e-168
Identities = 501/1394 (35%), Positives = 651/1394 (46%), Gaps = 245/1394 (17%)
Query: 1616 KKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTSGG--CGRYLTPYDSLL 1673
+++ Q +LA +L + + + +SP + K K S R P
Sbjct: 1419 QRRYKEKQRELA-RLQRKHDHERDESSRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSD 1477
Query: 1674 GKNRKALAKGLGLSLKSSREGKHKRAAKTR-KMEVGFKARGQPKSAHSPFASEVSSYSYN 1732
GK KA+ LGL R G AK R K+E A Q S + S
Sbjct: 1478 GKKVKAVRTSLGLLCAELRGGSGGEPAKKRSKLERSVYAGLQTASVEKAQCKKSSCQGGL 1537
Query: 1733 TDSEEDEEF-LKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGG--PKLTKRGLA----AP 1785
S LK + ++G P+ L S K + G KL++ A A
Sbjct: 1538 APSVAHRVAQLKPKVKSKG------LPTGLSSFQQKEATPGGRIREKLSRAKSAKVSGAT 1591
Query: 1786 RTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGG 1845
R +PK SR+ P C A+ S + S E +G
Sbjct: 1592 RHPQPKGHGSRETPRC------PAQPSVAASQE------------------------AGN 1621
Query: 1846 GYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPS-LSVVQLEAKQKARKKEERQS 1904
GY E L GLL AS +GPS SVV++EA QKA+KK+ERQ
Sbjct: 1622 GYDSEDCEGLLGTEAPPREAGLLLHTGASVA---VLGPSPSSVVKMEANQKAKKKKERQG 1678
Query: 1905 LLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLA 1964
LLG + ESEVK+++RS ++ K G + PG R P KAK
Sbjct: 1679 LLGA-CRLSSPESEVKIKRRS----VKAKVG------TTLERAPGQRPPGALGKKKAK-- 1725
Query: 1965 VEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTS 2024
G+ LR E G S D L+ R+
Sbjct: 1726 ---GKAKGSLRA------EPGATPSRDALFNPSRA------------------------- 1751
Query: 2025 RCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTA 2084
+ R++ + + R +KG P + + AL +A ++
Sbjct: 1752 -------FACREEGSQLASERLKRATRKGTVLQP---VLRRKNGALSITLATRNAKAILG 1801
Query: 2085 AKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPR------G 2138
R +K K K K+ GKG AVS+L+ES A EEDFE + +SSFSE+E G
Sbjct: 1802 KGRKLSKVKHKAGKQ---GKGRAVSRLLESFAVEEDFEFDDNSSFSEEEEDEEEEEEDSG 1858
Query: 2139 GAVERPLTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGN 2198
RSC I K++L+DGL VLIP +D LLYAG V+T+ PDIY +V+EGERGN
Sbjct: 1859 PLSAEQSAALARSCAIHKEDLRDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGN 1918
Query: 2199 RPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLL-DLEDDG 2257
R IY LEQLLQEA++DVRP S+R+LP GTR+ AYWSQ+ RCLYPG VVRG D ++D
Sbjct: 1919 RQRIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVVRGASGDEDEDL 1978
Query: 2258 DLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDG 2317
D + VEFDDGDTG I +S++RLLPPD+KIQC EPSPALLV S+ RR++K S
Sbjct: 1979 DSVVVEFDDGDTGHIAVSNVRLLPPDFKIQCTEPSPALLVSSSCRRTKKVS--------- 2029
Query: 2318 GTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPP 2377
SE P PS A + ++G P AL+ TPG K
Sbjct: 2030 ----SEAP---------PPSEAATPSLSPKAQDG---------PEALK---TPGKKSISK 2064
Query: 2378 EPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKP 2437
DK KA P+ A F +PL++ A
Sbjct: 2065 ---DKAGKAELLTSGAKSPTGASDHFLGRRG----------------SPLLSWSAVAQTK 2105
Query: 2438 KKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRED---PGAGGWQE 2494
+KA AA G PG + L +L+ S K +A+EAL P G
Sbjct: 2106 RKAVAAASKG------PGV-LQNLFQLNG----SSKKLRAREALFPVHSVATPIFGNGFR 2154
Query: 2495 PKSLLSLGS-YPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDK--AQAEQ 2551
S SL S Y P G + P P + L + + E G ++ + + +
Sbjct: 2155 ADSFSSLASSYAPFVGGTGPGLP--RGAHKLLRAKKAERVEAEKGGRRRAGGEFLVKLDH 2212
Query: 2552 DGAEESESSSSSSSGSSSSSSSSS-----SSGSETEGEEEG-DKNGDGGCGT--GGRNCS 2603
+G ++ + + S S S G DK G G
Sbjct: 2213 EGVTSPKNKTCKALLMGDKDFSPKLGRPLPSPSYVHPALVGKDKKGRAPIPPLPMGLALR 2272
Query: 2604 AASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2663
+ +A P S SS S ++ S + S SSSSS SS+SSSS S
Sbjct: 2273 KYAGQAEFPLPYDSDCHSSFSDEDEDGPGLAAGVPSRFLARLSVSSSSSGSSTSSSSGSV 2332
Query: 2664 SSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPT-----KATKQAGKARPSAHSP- 2717
S+SS SS +EDSS SSDDE PA +PT +A + G P AH+
Sbjct: 2333 STSSLCSSD-NEDSSYSSDDED-PALLLQTCLTHPVPTLLAQPEALRSKGSG-PHAHAQR 2389
Query: 2718 ---GKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVEN 2774
+ T A P + +KS+ K++E + KEL++RQR PSVEN
Sbjct: 2390 CFLSRATVAGTGAGSGPS----------SSSKSKLKRKEALSFSKAKELSRRQRPPSVEN 2439
Query: 2775 RPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIRIGDCAVFLSAGRPN 2834
RPKI+AFLPARQLWKW G PTQRRGMKGKARKLFYKAIVRG+E +R+GDCAVFLSAGRPN
Sbjct: 2440 RPKISAFLPARQLWKWSGNPTQRRGMKGKARKLFYKAIVRGEETLRVGDCAVFLSAGRPN 2499
Query: 2835 LPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKQFHQGQHWDQKSSRSLPAALRVSSQ 2894
LPYIGRI+SMWESWG+NMVV+VKWFYHPEET GK+ G++
Sbjct: 2500 LPYIGRIESMWESWGSNMVVKVKWFYHPEETKLGKRQCDGKN------------------ 2541
Query: 2895 RKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQDSEGLYYLAGTYEPT 2954
ALYQS H DENDVQT+SHKC VV EQYEQM +++K QD + LYYLAGTY+PT
Sbjct: 2542 -------ALYQSCHEDENDVQTISHKCQVVAREQYEQMARSRKCQDRQDLYYLAGTYDPT 2594
Query: 2955 TGMIFSTDGVPVLC 2968
TG + + DGVP+LC
Sbjct: 2595 TGRLVTADGVPILC 2608
Score = 401 bits (1030), Expect = e-111
Identities = 514/1821 (28%), Positives = 740/1821 (40%), Gaps = 373/1821 (20%)
Query: 1 MDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRL----PASGLPGPLPPGKYMAG- 55
MDGRDF P PP LLS HR AA A RL PA+ P PGKY
Sbjct: 1 MDGRDFAP-------PPHLLSERGSLGHR-SAAAAARLAPAGPAAQPPAHFQPGKYFPSP 52
Query: 56 LNLHPH----------PGEAFLGSFVASGMGPSASSHGS-PVPLPSDLSFRSPTPSNLPM 104
L + H P +F+GSF+ S +G +AS+H S P P + ++R P+
Sbjct: 53 LPMASHTASSRLMGSSPASSFMGSFLTSSLGSAASTHPSGPSSSPPEQAYRGSHPTTS-- 110
Query: 105 VQLWAAHAHE--GFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGG 162
Q+W +H+HE G+ L ++L ++HL+ + + L GQ + TQK
Sbjct: 111 -QIWFSHSHEAPGYPRFSGSLASTFLPVSHLDHHGNSNVLY---GQHRFYGTQK------ 160
Query: 163 DGFYLPTAGAPGSL---HSHAPSARTPGGGHSSGAPAK------GSSSRDGP-------- 205
D FYL +L + + PS H G+ ++ S + GP
Sbjct: 161 DNFYLRNLPPQPTLLPANHNFPSVARAAPAHPMGSCSRDRDRGEAGSLQKGPKDFDRFLV 220
Query: 206 ----AKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLA-- 259
+E+AG+ E GK+ P A E+ R + L A R+ PR A
Sbjct: 221 GKELGREKAGKAAE-----GKERPAAE-EDGGKERHKLVLPVPADGHCREGGPAPRGACE 274
Query: 260 ---ERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEG-- 314
+ L+ L +K N + + L C GG +G P AKEAA E
Sbjct: 275 GRPKHLTSCLLNTKVLNGEMGRAALASCAGGM--LGRPGTGVVTSGRCAKEAAGPPEPGP 332
Query: 315 --ARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAP 372
+ L R + L P P A P P G+ + + R+ + P
Sbjct: 333 AFSECLERRQMLHHTASYAGPPPPLSTAAGSFPCLQLHGGPDGLCPLQDKAPRDLKASGP 392
Query: 373 TFVPSVEAFDERPGPIQIASQ---ARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREK 429
TFVPSV ++ P Q A A + + R E AP G + EG E+
Sbjct: 393 TFVPSVGHLADKGRPFQAAEACAVAGEGKDRHLEGTMAPDHAAPYGVSYAHLKAEGKGER 452
Query: 430 NSVIRSLKRPPPADA---PTVRA----TRASPD------PRAYVPAKELLKPEADPRPCE 476
RP +A P ++ + A P+ P++ + + + C
Sbjct: 453 --------RPGGFEAALNPRLKGLDYLSSAGPEASFPGLPKSGLDKSGYFELPTSSQDCA 504
Query: 477 R-APRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHHSRA 535
R + P G A QA G+ P GP A ++A + Q H A
Sbjct: 505 RPGHQDPLGGKAPQACCTLDKTVGKEAPAGPP-----------GAQKVARIRHQQHLMAA 553
Query: 536 EEEAAVVAASSSKKAYL-----DPGAVLPRSAATCGRPVA-----DMHSAAH----GSG- 580
E E + A + +K+ G LP G+ A + + A+ GSG
Sbjct: 554 EVEQGGIGAEAKRKSLELASLGYSGPHLPPWGVQAGQGTAMAISEERKAGAYLDPFGSGL 613
Query: 581 ---------------EASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAP 625
E SAM++L+KYS A+ V G+K+P GLG +K
Sbjct: 614 QQAALLPQELPAPPDEVSAMKNLLKYSSQ----ALVV-----GQKAPLVGLGGLK----- 659
Query: 626 TSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIA 685
A + +A+ S GP ERP+ A++ RE G+ EVR PPVGIA
Sbjct: 660 --ASCIQQEAKFLSSKGPGQS---------ERPDCARS--REHDTTHGDGEVRQPPVGIA 706
Query: 686 VAVARQKDSGGSGRLGPGLVDQERSLSLSNVKGHGRA-DEDCVDDRARHREERLLGARLD 744
VA+ARQKD+ G + + KG G +D A RL RL
Sbjct: 707 VALARQKDTVSRSEAAYGTNTARQGRAAPAFKGGGGPRSTHALDLEAEEERTRLCDDRLG 766
Query: 745 -RDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATHP 803
+E LL++SK+ + AR+HP S P L P+LM+ SG+ DPA H HP
Sbjct: 767 LASRELLLQDSKDRVEFARIHPPSSCPGDLAPHLMMQ-------SGQLGGDPAPHTHPHP 819
Query: 804 -WLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIP 862
WLPR+ + S+W+ GH YGLG P+LHQ + P FP + G +PS + +D + QLV++P
Sbjct: 820 PWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVFPLPQDAPT-QLVILP 878
Query: 863 SDHLPH-----FAELMERATVPPLWPALYPPGRSPLHHAQ---QLQLFSQQHFLRQQEFL 914
S+ PH A++M++A+ LWP +Y GR P H Q QL ++S+ LRQQE
Sbjct: 879 SEPTPHSAPHALADVMDQAS---LWPPMY-GGRGPASHMQHPGQLPVYSRPQLLRQQELY 934
Query: 915 YLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRK 974
LQQQ +A + QR K ++ ++EE A KA +T P L
Sbjct: 935 ALQQQ--RAAQFQR---------KPEDQHLDLEE-------PAQEKAPKSTHKPVALTPT 976
Query: 975 PPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSP 1034
PG PSP A P KL PP P P+S PT P
Sbjct: 977 APG---------------APSPAAGPT---------KLPPCCHPPD---PKPPASSPTPP 1009
Query: 1035 PPASPP----------PTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRY-- 1082
P S P P PG +R A E E + + P D+PP Y
Sbjct: 1010 PRPSAPCTLNVCPASSPGPG-SRVRSAEEKNGEGQQSTADIITSEP------DLPPGYLR 1062
Query: 1083 PFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITE 1142
P L G P + + D + + P P R L E P SP + E
Sbjct: 1063 PMAGL----GFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPP--CSPRSLEE 1116
Query: 1143 P-LREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLL 1201
P L G E A +++ A + GP P PL + + LL
Sbjct: 1117 PGLLSGARE---ATQDLAATPYPTERGPQ--GKAADPSPLEGLQELQC--------AALL 1163
Query: 1202 EAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQL---TPETLVEAK 1258
EA ATGQ+ + E R G P + A ++ +P L +
Sbjct: 1164 EAGGPEATGQAHSTQG------GAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEG 1217
Query: 1259 EEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVP--- 1315
E+P P + + E+ L Q + +S+ DC G + P A+P
Sbjct: 1218 EQP------APEEDELEEDELGQQSMEDSE-----EDCG-----GAPDNSHPPRALPGLD 1261
Query: 1316 -VLGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAA 1374
++ +T L + SD S DP AA+ P PLP
Sbjct: 1262 ALVAATINLGDLPSD----SPPDPQP-----PAASGPPSTVPLP---------------- 1296
Query: 1375 ESLVLEQSFLHGITLLSEIAELELER-RSQEMGGAERALVARPSLESLL----------A 1423
S +HGI LLSE+A+L ++R RS+ E V +L+ L A
Sbjct: 1297 -----HSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVEA 1351
Query: 1424 AGSHMLREVLDGPVVDPLKNLRL-PRELKPNKKYSWMRKKEERMYAMKSSLEDMDALELD 1482
AG P +P RL PR +K +W K + + +K++++ +D E+
Sbjct: 1352 AGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTW-TPKTKPVCPLKAAIDRLDTQEVG 1410
Query: 1483 FRMRLAEVQRQYKEKQRELVKLQRRRDSEDRREEPHRSLARRGPGRPRKRTHAPSALSPP 1542
R+RLAE+QR+YKEKQREL +LQR+ D E R+E RS ARRGPGRPRKR H+ S+L P
Sbjct: 1411 MRVRLAELQRRYKEKQRELARLQRKHDHE--RDESSRSPARRGPGRPRKRKHS-SSLPAP 1467
Query: 1543 RKRGKSGHSSGKLSSKSLLTS-----DDYELGAGIRKRHKGSEEEHDALIGM-----GKA 1592
R G S GK K++ TS + G+G K S+ E G+ KA
Sbjct: 1468 RPTGPLPRSDGK-KVKAVRTSLGLLCAELRGGSGGEPAKKRSKLERSVYAGLQTASVEKA 1526
Query: 1593 RGRNQTWDEHEASS--DFISQLKIKKKK------MASDQEQLAS---KLDKALSLTKQDK 1641
+ + + A S ++QLK K K ++S Q++ A+ ++ + LS K K
Sbjct: 1527 QCKKSSCQGGLAPSVAHRVAQLKPKVKSKGLPTGLSSFQQKEATPGGRIREKLSRAKSAK 1586
Query: 1642 LKSPFKFSDSAGGKSKTSGGC 1662
+ + G S+ + C
Sbjct: 1587 VSGATRHPQPKGHGSRETPRC 1607
Score = 59.3 bits (142), Expect = 5e-08
Identities = 120/508 (23%), Positives = 179/508 (35%), Gaps = 94/508 (18%)
Query: 2334 RKPSAKAKGDRAATLEEGNPTDEVPST--PLALEPSSTPGSKKSPPEPVDKRAKAPKARP 2391
RKP D+ LEE ST P+AL P++ PG+ P P K P P
Sbjct: 946 RKPE-----DQHLDLEEPAQEKAPKSTHKPVALTPTA-PGA----PSPAAGPTKLP---P 992
Query: 2392 APPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKP-KKARAAEESGAKG 2450
P P PPA + P P P A P L PA+ P P + R+AEE +G
Sbjct: 993 CCHPPDPKPPASSPTPPPRPSA----------PCTLNVCPASSPGPGSRVRSAEEKNGEG 1042
Query: 2451 PRRPGE----EAEL----LVKLDHEGVTSPKSKKAKEALLLREDP------GAGGWQEPK 2496
+ + E +L L + G + P + EDP G EP
Sbjct: 1043 QQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNL----EDPETMQTTAPGAQPEPT 1098
Query: 2497 SLLSLGSYPPAAGSS--EP--------------KAPWP--KATDGDLAQEPGP--GL--- 2533
G PP + S EP P+P + G A +P P GL
Sbjct: 1099 RTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGK-AADPSPLEGLQEL 1157
Query: 2534 ---TFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSS-------SSSSGSETEG 2583
++G P++ +A + Q GA E S G SS +SS S E EG
Sbjct: 1158 QCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEG 1217
Query: 2584 EE--------EGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSS 2635
E+ E D+ G +C A + P + + +++ + S S
Sbjct: 1218 EQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDS 1277
Query: 2636 SSSSSSSSSSSSSSS---SSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG 2692
++S S+ SS + S + + + + ++E A
Sbjct: 1278 PPDPQPPAASGPPSTVPLPHSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFNLQ 1337
Query: 2693 PSAQAALPTKATKQAGKARPSAHS-PGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRP-- 2749
A A + AG +A + P P P+ P Q LQ K K++P
Sbjct: 1338 HLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGPRLTPRM--QILQRKDTWTPKTKPVC 1395
Query: 2750 KKREGVHLPTTKELAKRQRLPSVENRPK 2777
+ + T+E+ R RL ++ R K
Sbjct: 1396 PLKAAIDRLDTQEVGMRVRLAELQRRYK 1423
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 121 bits (304), Expect = 9e-27
Identities = 134/434 (30%), Positives = 180/434 (41%), Gaps = 49/434 (11%)
Query: 2370 PGSKKSPPEPVDKRAKAPKAR--PAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPL 2427
P S ++P P P++ AP + + A PA A + APA S A
Sbjct: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARM-APALSGANLTS 2382
Query: 2428 ITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDP 2487
+P + + R + + R A ++ E SP S+ + P
Sbjct: 2383 PRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP 2442
Query: 2488 GAGGWQEP-------KSLLSLGSYPPAAGS---SEPKAPWPKATDGD---LAQEPGPGLT 2534
+ P +S + P AGS S ++ GD + P PG+
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Query: 2535 FEDSGNPKSPDKAQ------AEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGD 2588
D G P + AQ A Q E SSSSSSS SSSSSSSSSSS S + G D
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562
Query: 2589 KNGDGGCGTGGRNCSAASSRAASPASSSSSS-----------SSSSSSSSSSSSSSSSSS 2637
G + A R SP + + + SSSSSSSSSSSS
Sbjct: 2563 SEGS----SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSS 2618
Query: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQA 2697
SSSSSSSSSSSSSSSSSSSSSSSSSSSSSS S + + P P ++
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP---GERRS 2675
Query: 2698 ALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHL 2757
P K +R ++SP ++ + P PQP+ Q + + SR +R
Sbjct: 2676 RSPRKPIDSLRDSRSLSYSPVER------RRPSPQPSPRDQQSSSSERGSRRGQRGDSRS 2729
Query: 2758 PTTKELAKRQRLPS 2771
P+ K +R+ PS
Sbjct: 2730 PSHK---RRRETPS 2740
Score = 82.0 bits (201), Expect = 8e-15
Identities = 107/427 (25%), Positives = 160/427 (37%), Gaps = 86/427 (20%)
Query: 2345 AATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAP---KARPAPPQPSPAPP 2401
AA L + T + L+ ++P S E V R P +AR P +P+
Sbjct: 2358 AAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS 2417
Query: 2402 AFTSCPAPEPFAEL-PAPATSLAPA----PLITMPATRPKPKKARAAEESGAKGPRRPGE 2456
TS AP P + + AP+ SL P P +P+ + A+ + G +
Sbjct: 2418 RMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSS 2477
Query: 2457 EAELLVKL---DHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSL------------ 2501
A DH G+ S + + + E P + G Q+P +L +L
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDV-GEPPASTGAQQPSALAALQPAKERRSSSSS 2536
Query: 2502 -----GSYPPAAGSSEPKAPWPKATDGD-----------LAQEPGPGLTFEDS---GNPK 2542
S ++ SS + ++D + L + P P +++ G P
Sbjct: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPP 2596
Query: 2543 SPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNC 2602
P A+ ++ + S SSSSSSS SSSSSSSSSS
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS-------------------------- 2630
Query: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2662
SSSSSSSSSSSSSSSSSS S + + +S S
Sbjct: 2631 --------------SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR 2676
Query: 2663 SSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATK---QAGKARPSAHSPGK 2719
S S S S + P+P P Q + ++ Q G +R +H +
Sbjct: 2677 SPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
Query: 2720 KTPAPQP 2726
+TP+P+P
Sbjct: 2737 ETPSPRP 2743
Score = 79.0 bits (193), Expect = 7e-14
Identities = 117/509 (22%), Positives = 170/509 (33%), Gaps = 80/509 (15%)
Query: 2298 PSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGR---GRKPSAKAKGDRAATLEEGNPT 2354
P ++R R TS D+ D + S AK GR PS A G R EG+
Sbjct: 255 PKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSP-ASGRRG----EGDAP 309
Query: 2355 DEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAE 2414
P T PSS + K P P + + K K + A +PSP+P ++ P P
Sbjct: 310 FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSA-TRPSPSPERSSTGPEPPAPTP 368
Query: 2415 LPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKS 2474
L A +P PL T P ++ P P EA SP
Sbjct: 369 LLAERHGGSPQPLATTPLSQE---------------PVNPPSEA------------SPTR 401
Query: 2475 KKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLT 2534
++ PKS L P + SSE P P+ T ++
Sbjct: 402 DRS----------------PPKSPEKL----PQSSSSESSPPSPQPTK----------VS 431
Query: 2535 FEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGG 2594
S +P+SP A A G+ SSS +S S + S S T G
Sbjct: 432 RHASSSPESPKPAPA--PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489
Query: 2595 CGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2654
G + R S + S S S+ S S S S S S ++
Sbjct: 490 AKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQ 549
Query: 2655 SSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSA 2714
S S+ S S S S S T ++ T A +++ P+
Sbjct: 550 RRGRSRSARRGRSHSRSPATRGRSRSR--------TPARRGRSRSRTPARRRSRSRTPTR 601
Query: 2715 HSPGKKTPA----PQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLP 2770
+TPA + + P + ++ P + P +R G T R R
Sbjct: 602 RRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSR 661
Query: 2771 SVENRPKIAAFLPARQLWKWFGKPTQRRG 2799
+ R + + PAR+ + + RRG
Sbjct: 662 TPARRGRSRSRTPARRSGRSRSRTPARRG 690
Score = 72.0 bits (175), Expect = 8e-12
Identities = 79/352 (22%), Positives = 131/352 (37%), Gaps = 63/352 (17%)
Query: 2503 SYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPD----KAQAEQDGAEESE 2558
S+ P + E K P P + P P +S + +SP K + ++D SE
Sbjct: 150 SFDPQRRAREAKQPAP--------EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSE 201
Query: 2559 SSSSSSSGSSSSSSSSSSSGSETEGEEEG-----------DKNGDGGCGTGGRNCSAASS 2607
SSS SS S SE++ + DK T S +
Sbjct: 202 SSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAH 261
Query: 2608 RAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---------SSSSSSSSSSS 2658
R+ S S+SSS +S S S S+++ + +++ + S S +S S ++S+
Sbjct: 262 RSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRP 321
Query: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDEAAPAP-----TAGPSAQAALPTKATKQAGKARPS 2713
SS +++ SS D+D P+P + GP A P A + G +P
Sbjct: 322 SSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL 381
Query: 2714 AHSP-------------------GKKTPAPQPQA-------PPPQPTQPLQPKAQAGAKS 2747
A +P K+P PQ+ P PQPT+ + + +
Sbjct: 382 ATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441
Query: 2748 RPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRG 2799
+P G H + + R R K + P+R++ + T +RG
Sbjct: 442 KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRG 493
Score = 66.2 bits (160), Expect = 4e-10
Identities = 108/442 (24%), Positives = 165/442 (37%), Gaps = 66/442 (14%)
Query: 2292 SPAL-LVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEE 2350
SP L VP R R +S + E KDG R PS +++ + L +
Sbjct: 1404 SPVLDAVPRTPSRERSSSASSPEMKDG--------------LPRTPSRRSRSGSSPGLRD 1449
Query: 2351 GNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKA-----PKARPAPPQP---SPAPPA 2402
G+ T S S+PG K P P R++ PKA P P+P SP+ P
Sbjct: 1450 GSGTPSRHSLS-----GSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504
Query: 2403 FTS-CPAPE---PFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEA 2458
+ C P+ +E ++A PL + ++ +++E K P E +
Sbjct: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPL-------GQRSRSGSSQELDVKPSASPQERS 1557
Query: 2459 ELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWP 2518
E +SP SK AK LR+ +G E S L +GSS P
Sbjct: 1558 E--------SDSSPDSK-AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP 1608
Query: 2519 KATDGDLAQEPGPGLTFEDSGNPKSPD-KAQAEQDGAEESESSSSSSS-GSSSSSSSSSS 2576
+A SG+ SP+ KA A + S S SSS G S SSS+
Sbjct: 1609 RAAPR------------AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE 1656
Query: 2577 SGSETEGEEEGDKNGDGGCGTGGRNCSAA----SSRAASPASSSSSSSSSSSSSSSSSSS 2632
S E + + G SSR++ + + S S S+SSS +
Sbjct: 1657 SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPET 1716
Query: 2633 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG 2692
S + S S SS + S SS S+SS + +T+ S S +
Sbjct: 1717 RSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSR 1776
Query: 2693 PSAQAALPTKATKQAGKARPSA 2714
+ T+ ++G ++ ++
Sbjct: 1777 SRREKTRTTRRRDRSGSSQSTS 1798
Score = 58.5 bits (140), Expect = 9e-08
Identities = 75/310 (24%), Positives = 112/310 (36%), Gaps = 54/310 (17%)
Query: 2506 PAAGSSE-PKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPD------KAQAEQDGAEESE 2558
P+ G SE +P PKA L Q P P S +P SP+ Q E+ G+E S
Sbjct: 1473 PSRGRSECDSSPEPKA----LPQTPRPR-----SRSPSSPELNNKCLTPQRERSGSESSV 1523
Query: 2559 SSSS---------SSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT-------GGRNC 2602
+ S SGSS S+ + E + + T G +
Sbjct: 1524 DQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP 1583
Query: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS----------------SSSSSS 2646
S SP S S SS ++ + S S SS S SSS
Sbjct: 1584 EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK 1643
Query: 2647 SSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQ 2706
S SSS+ SS S ++ SS ++ P S + T+ +
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
Query: 2707 AGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSR-PKKREGVHLPTTKELAK 2765
+ ++R ++ SP ++ + PP P + KSR ++R P TK ++
Sbjct: 1704 SRRSRSASSSPETRS-----RTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758
Query: 2766 RQRLPSVENR 2775
R R PS + R
Sbjct: 1759 RGRSPSPKPR 1768
Score = 57.8 bits (138), Expect = 2e-07
Identities = 111/520 (21%), Positives = 167/520 (32%), Gaps = 60/520 (11%)
Query: 2290 EPSPALLVPSAKRR--SRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAAT 2347
+P+PA P + R S TSK+ G+ ++ GR R P AT
Sbjct: 442 KPAPA---PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP---------AT 489
Query: 2348 LEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFT--- 2404
+ G P T S +P ++S R+++P+ R SP P ++
Sbjct: 490 AKRGRSRSRTP-TKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGR--SRSPQRPGWSRSR 546
Query: 2405 -------SCPAPEPFAELPAPAT-----SLAPA----PLITMPATRPKPKKARAAEESGA 2448
S A + +PAT S PA PA R + S +
Sbjct: 547 NTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRS 606
Query: 2449 KGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRED-------PGAGGWQEPKSLLSL 2501
+ P R G SP ++++ R P G ++
Sbjct: 607 RTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARR 666
Query: 2502 G---SYPPAAGSSEPKAPWPKATDGDLAQEPGPG------LTFEDSGNPKSPDKAQAEQD 2552
G S PA S ++ P ++ P G L + ++P +
Sbjct: 667 GRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGS 726
Query: 2553 GAEESESSSSSS--SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAA 2610
+E S +S S S+SS S S R + SS
Sbjct: 727 SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP 786
Query: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670
S + S S SS + S + S SSSS S + S S SSSS S
Sbjct: 787 KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846
Query: 2671 STTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSP-GKKTPAPQPQAP 2729
T S +S + T P ++ + + PS HS G P + P
Sbjct: 847 GTPPRQGSITSPQANEQSVT--PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP 904
Query: 2730 P---PQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKR 2766
P P + QPK +A R + G P+ + R
Sbjct: 905 PRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSR 944
Score = 57.0 bits (136), Expect = 3e-07
Identities = 102/505 (20%), Positives = 180/505 (35%), Gaps = 62/505 (12%)
Query: 2301 KRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPST 2360
+RR+R+ + E + E +++ +K K K DR E +P E +
Sbjct: 154 QRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKK-DRGRRSESSSPRRERKKS 212
Query: 2361 PLALEPSSTPGSKKSP---PEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPA 2417
+ S SKK P P KR K R +PAP + A
Sbjct: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRR--------AHRST 264
Query: 2418 PATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKA 2477
A S + + +R + + A A + A R P SP S +
Sbjct: 265 SADSASSSD-----TSRSRSRSAAAKTHTTALAGRSP----------------SPASGRR 303
Query: 2478 KEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWP---KATDGDLAQEPGPGLT 2534
E +PG Q P S P + +P +P+ K A P P
Sbjct: 304 GEGDAPFSEPGTTSTQRPSS--------PETATKQPSSPYEDKDKDKKEKSATRPSPSPE 355
Query: 2535 FEDSG-NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDG 2593
+G P +P AE+ G +++ S + S +S + + +K
Sbjct: 356 RSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ- 414
Query: 2594 GCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2653
++SS ++ P+ + S +SSS S + + S SSS +S + S
Sbjct: 415 ----------SSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSH 464
Query: 2654 SSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPS 2713
+ S S + S + ++ + PT +++ P ++ +
Sbjct: 465 GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524
Query: 2714 AHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVE 2773
+ SP ++ + PQ P ++ Q + + ++S + R P T+ R R P+
Sbjct: 525 SRSPQRRGRSRSPQRPGWSRSRNTQRRGR--SRSARRGRSHSRSPATRG-RSRSRTPARR 581
Query: 2774 NRPKIAAFLPARQLWKWFGKPTQRR 2798
R + + PAR+ + PT+RR
Sbjct: 582 GRSR--SRTPARRRSR-SRTPTRRR 603
Score = 57.0 bits (136), Expect = 3e-07
Identities = 122/602 (20%), Positives = 205/602 (34%), Gaps = 120/602 (19%)
Query: 2289 AEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATL 2348
+ P A PS S KD + + T S P + G P A A
Sbjct: 322 SSPETATKQPS----SPYEDKDKDKKEKSATRPSPSPERSSTG----PEPPAPTPLLAER 373
Query: 2349 EEGNPTDEVPSTPLALEP-----SSTPGSKKSPPEPVDKRAKAPKARPAPPQPSP----- 2398
G+P + +TPL+ EP ++P +SPP+ +K ++ + +PP P P
Sbjct: 374 HGGSP-QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSR 432
Query: 2399 ----APPAFTSCPAPEPFAELPA-------------------------------PATSLA 2423
+P + PAP E+ + PAT+
Sbjct: 433 HASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKR 492
Query: 2424 PAPLITMPATR-------PKPKKARAAEESG----------AKGPRRPGEEAELLVKLDH 2466
P R P+ +++R+A+ G ++ P+RPG +
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQ--- 549
Query: 2467 EGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLG---SYPPAAGSSEPKAPWPKATDG 2523
+S+ A+ P G ++ G S PA S + P + +
Sbjct: 550 ---RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRS 606
Query: 2524 DLAQEPG------PGLTFEDSGNP---KSPDKAQAEQDGAEESESSSSSSSGSSSSSSSS 2574
G P + +P +S ++ A + G S + + S + +
Sbjct: 607 RTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARR 666
Query: 2575 SSSGSETEGEEEGDKNGDGGCGTG---------GRNCSAA-----SSRAASP-----ASS 2615
S S T G G GR+ S + S + +P + S
Sbjct: 667 GRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGS 726
Query: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
SS + S +S S S+SS S SS S S SS S + S S S S S+
Sbjct: 727 SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP 786
Query: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATKQAG-------KARPSAHSPGKKTPAPQPQA 2728
+ + + ++ P A++ P + ++ + PS S +P P+ ++
Sbjct: 787 KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846
Query: 2729 PPPQPTQPLQPKAQAGAKS-RPKKR---EGVHLPTTKELAKRQRLPSVENRPKIAAFLPA 2784
P P Q QA +S P++R E P K + S + P++ + P
Sbjct: 847 GTP-PRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPP 905
Query: 2785 RQ 2786
RQ
Sbjct: 906 RQ 907
Score = 55.1 bits (131), Expect = 1e-06
Identities = 117/508 (23%), Positives = 182/508 (35%), Gaps = 79/508 (15%)
Query: 2292 SPALLVPSAKRRSRKTSKDTGEGKDG-GTAGSEEPGAKARGRGRKPSAKAKGD-RAATLE 2349
S +L P +K +SR + + + G S+ P ++R +P AK++ R +
Sbjct: 759 SRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSS 818
Query: 2350 EGNPTDEVPSTPLALE-PSSTPGSK-KSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCP 2407
P + TP SS+P K KS P +P+A P F S P
Sbjct: 819 SSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRS-CFESSP 877
Query: 2408 APEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLV---KL 2464
PE + P+ + +P +T P+ +R++ P + + ++ +
Sbjct: 878 DPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS---------PQPKVKAIISPRQR 928
Query: 2465 DHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGD 2524
H G +SP + R +S L L Y + GSS P D
Sbjct: 929 SHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRL-LPRYSHS-GSSSP--------DTK 978
Query: 2525 LAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGE 2584
+ E P + S +P KAQ G S S S S S S GS +
Sbjct: 979 VKPETPPRQSHSGSISPYPKVKAQTPP-GPSLSGSKSPCPQEKSKDSLVQSCPGSLS--- 1034
Query: 2585 EEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
A ++++P S SS S +S S +SS
Sbjct: 1035 ------------------LCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEV 1076
Query: 2645 SSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCS------SDDEAAPAPTAGPSAQ-- 2696
S S S S S S +S S SSS E +S S + A+P +G S +
Sbjct: 1077 RQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQS 1136
Query: 2697 ------AALPT-KATKQAGKAR-PSAHSPGKKTPAPQPQAPPPQPTQ-------PLQPKA 2741
++ PT + G++R +A S K PQ A P Q P+Q +
Sbjct: 1137 RFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRP 1196
Query: 2742 QAG------AKSRPKKREGV-HLPTTKE 2762
++ ++ P++R G P TKE
Sbjct: 1197 ESSLVFKDTLRTPPRERSGAGSSPETKE 1224
Score = 54.3 bits (129), Expect = 2e-06
Identities = 94/446 (21%), Positives = 150/446 (33%), Gaps = 34/446 (7%)
Query: 2325 PGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRA 2384
PG K G++P+ A E+ N E + S GS P + A
Sbjct: 105 PGGKEETPGQRPAVTETHQLAELNEKKN---ERLRAAFGISDSYVDGSSFDPQRRA-REA 160
Query: 2385 KAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATR----PKPKKA 2440
K P P PP+P +S +P P + + P K KK
Sbjct: 161 KQPA--PEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKH 218
Query: 2441 RAAEESGAKGPRRPGEEAELLVK-----LDHEGVTSPKSKKAKEALLLREDPGAGGWQEP 2495
R+ ES + R P +++ K +PKS++A + + +
Sbjct: 219 RSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
Query: 2496 KSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAE 2555
+ ++ A P + +GD A PG T + P SP+ A +
Sbjct: 279 SRSAAAKTHTTALAGRSPSPASGRRGEGD-APFSEPGTT--STQRPSSPETATKQPSSPY 335
Query: 2556 ESESSSSSSSGSS--SSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRA---- 2609
E + ++ S S SS+G E GG +
Sbjct: 336 EDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPS 395
Query: 2610 -ASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668
ASP S S SSSS SS S + S +SSS S + + S SS
Sbjct: 396 EASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISS 455
Query: 2669 SSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQA 2728
S ++ + + D++ + ++ P AT + G++R +TP + +
Sbjct: 456 SPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP--ATAKRGRSR-------SRTPTKRGHS 506
Query: 2729 PPPQPTQPLQPKAQAGAKSRPKKREG 2754
P AQ +SR +R G
Sbjct: 507 RSRSPQWRRSRSAQRWGRSRSPQRRG 532
Score = 52.8 bits (125), Expect = 5e-06
Identities = 94/452 (20%), Positives = 152/452 (33%), Gaps = 81/452 (17%)
Query: 2300 AKRRSR------KTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKG-DRAATLEEGN 2352
A+RRSR + S+ + G + S P + R R R P+ + + R G
Sbjct: 621 ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGR 680
Query: 2353 PTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPF 2412
P+ S TP +S + +R ++ P S +
Sbjct: 681 SRSRTPARR-GRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGS------------- 726
Query: 2413 AELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSP 2472
+ + K+R ++ ++ P + + ++SP
Sbjct: 727 --------------------SSERKNKSRTSQRR-SRSNSSPEMKKSRISSRRSRSLSSP 765
Query: 2473 KSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPA---AGSSEPKAPWPKATDGDLAQEP 2529
+SK L R G+ + KS PP +GSS+PKA
Sbjct: 766 RSKAKSRLSLRRSLSGSSPCPKQKS-----QTPPRRSRSGSSQPKAK------------- 807
Query: 2530 GPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDK 2589
S P ++ + ++S++ S S SSS S +G +
Sbjct: 808 --------SRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQ 859
Query: 2590 NGDGGCGTGGRNCSAAS------SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
+ R+C +S SR S S S SS SS+ S S SSS
Sbjct: 860 ANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKV 919
Query: 2644 SSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKA 2703
+ S S S SSS S S +S ++ S S+ E+ P S ++ TK
Sbjct: 920 KAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKV 979
Query: 2704 TKQAGKARPSAHSPGKKTPAPQPQA-PPPQPT 2734
+ P G +P P+ +A PP P+
Sbjct: 980 KPE---TPPRQSHSGSISPYPKVKAQTPPGPS 1008
Score = 51.6 bits (122), Expect = 1e-05
Identities = 103/504 (20%), Positives = 173/504 (34%), Gaps = 57/504 (11%)
Query: 2298 PSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEV 2357
PSA + R S + + K A + P + G P +K + + EV
Sbjct: 1549 PSASPQERSESDSSPDSK----AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV 1604
Query: 2358 PSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPA 2417
P A P + GS SP EP KAP R P + + P+PE +
Sbjct: 1605 KDKPRAA-PRAQSGSDSSP-EP-----KAPAPRALPRRSRSGSSSKGRGPSPEG-----S 1652
Query: 2418 PATSLAPAPLITMPATRPKPKKARAAEESGAKG---PRRPGEEAELLVKLDHEGVTSPKS 2474
+T +P P +R + +R++ E K PRR + +L + S +S
Sbjct: 1653 SSTESSPEH---PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS--PELTRKARLSRRS 1707
Query: 2475 KKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLT 2534
+ A + P P+ S P+ S EP + A P T
Sbjct: 1708 RSASSS------PETRSRTPPRHRRS-----PSVSSPEPAEKSRSSRRRRSASSPRTKTT 1756
Query: 2535 FEDSGNPK-SPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDG 2593
+P P Q + + ++ ++ S SS S+S + + G
Sbjct: 1757 SRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRG 1816
Query: 2594 GCGTGGRN-CSAASSRAAS----------PASSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
G G R+ SSR +S P S S S +S + S S +S ++ S
Sbjct: 1817 GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRS 1876
Query: 2643 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD------DEAAPAPTAGPSAQ 2696
S + S S S +S S S S +S T S + + P ++
Sbjct: 1877 RSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR 1936
Query: 2697 AALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPL---QPKAQAGAKSRPKKRE 2753
+ PT + + P + P + T P+ + +++ +R + R
Sbjct: 1937 SRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRS 1996
Query: 2754 GVHLPTTKELAKRQRLPSVENRPK 2777
P T+ ++ + P R +
Sbjct: 1997 RTS-PVTRRRSRSRTSPVTRRRSR 2019
Score = 44.3 bits (103), Expect = 0.002
Identities = 156/764 (20%), Positives = 259/764 (33%), Gaps = 110/764 (14%)
Query: 1416 PSLESLLAAGSHMLREVLDGPVVD-----PLKNLRLPRELKPNKKYSWMRKKEERMYAMK 1470
PSL+S R PV + P++ R P K S M ++ R +
Sbjct: 1084 PSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK-SGMSPEQSRFQSDS 1142
Query: 1471 SSLEDMDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDSEDRREEPHRSLARRGP---- 1526
SS +D+ L + RL + + K ED P R + P
Sbjct: 1143 SSYPTVDSNSLLGQSRLETAESKEK---------MALPPQEDATASPPRQKDKFSPFPVQ 1193
Query: 1527 GRPRKRTHAPSAL-SPPRKRGKSGHSSGKLSSKSLL--TSDDYELGAGIRKRHKGSEEEH 1583
RP L +PPR+R +G S S L +S D EL + K SEE
Sbjct: 1194 DRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEK----SEEPA 1249
Query: 1584 DALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLK 1643
++ + + + E+S + ++ ++ LD++ S + ++
Sbjct: 1250 GQILSHLSSELKEMSTSNFESSPE------------VEERPAVSLTLDQSQSQASLEAVE 1297
Query: 1644 SPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTR 1703
P S S G + +P L N G L+ G
Sbjct: 1298 VP----------SMASSWGGPHFSPEHKELS-NSPLRENSFGSPLEFRNSGP-----LGT 1341
Query: 1704 KMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCS 1763
+M GF + + + + PF +++ TD D + + + G SSS+L+P +
Sbjct: 1342 EMNTGFSSEVK-EDLNGPFLNQLE-----TDPSLDMK--EQSTRSSGHSSSELSPDAVEK 1393
Query: 1764 MVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLL-LREAEARSSFSDSSEESFD 1822
++++ P L A PRT + ++S P L +R S S SS D
Sbjct: 1394 AGMSSNQSISSPVLD----AVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRD 1449
Query: 1823 QDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVG 1882
+ SG + R S G E + P P
Sbjct: 1450 GSGTPSRHS----------LSGSSPGMKDIPRTPSRGRSE----------CDSSPEPKAL 1489
Query: 1883 PSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEV--KVRKRSPAGLLRPKKGLGEPG 1940
P + E L + E + SES V K R+P G R + G +
Sbjct: 1490 PQ---TPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQ-RSRSGSSQEL 1545
Query: 1941 PSLAAPTPGARGPDPSSPD-KAKLAVEKGRKAR---------KLR-GPKEPGFEAGPEAS 1989
+ +P R SSPD KAK +++R K R P+ + PE
Sbjct: 1546 DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVK 1605
Query: 1990 DDDLWTRRRSERIFLHDASAA--APAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDP 2047
D R D+S APAP + +++ +KG SP + + P
Sbjct: 1606 DKPRAAPRAQSG---SDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662
Query: 2048 RKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKENRGKGGA 2107
K + + + P ++ P + + LT R +++ E R +
Sbjct: 1663 PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPP 1722
Query: 2108 VSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAV-ERPLTPAPR 2150
+ S+++ E E ++ S PR R +P+P+
Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
Score = 44.3 bits (103), Expect = 0.002
Identities = 46/190 (24%), Positives = 67/190 (35%), Gaps = 22/190 (11%)
Query: 1789 KPKPATSRKQPFCLL-LREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGY 1847
+P +T +QP L L+ A+ R S S SS S SS +SG
Sbjct: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS-------SSGSS- 2559
Query: 1848 RLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLG 1907
S E S L + A +PSPT P +V + + K +R+S
Sbjct: 2560 ---------SSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSS 2610
Query: 1908 TEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPD----PSSPDKAKL 1963
+ + S S S + S ++P+P GP P+SP K
Sbjct: 2611 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670
Query: 1964 AVEKGRKARK 1973
+ R RK
Sbjct: 2671 GERRSRSPRK 2680
Score = 43.1 bits (100), Expect = 0.004
Identities = 55/246 (22%), Positives = 94/246 (38%), Gaps = 36/246 (14%)
Query: 2230 IAAYWSQQYRCLYPGTV-VRGLLDLEDDGDLITVEFDDGDTG---RIP---LSHIRLLPP 2282
+ + +S Q RCL T V G L G + T GD +P + H + P
Sbjct: 2451 VPSAFSDQSRCLIAQTTPVAGSQSLSS-GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP 2509
Query: 2283 DYKIQCAEPSP-ALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAK 2341
+PS A L P+ +RRS +S + ++ S S+ +
Sbjct: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS--------------SSSSS 2555
Query: 2342 GDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKS-----PPEPVDKRAK------APKAR 2390
+++ EG+ P L PS TP K++ PPEP + K + +
Sbjct: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615
Query: 2391 PAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKP--KKARAAEESGA 2448
+ S + + +S + + + ++S +P+P P PKP K E +
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRS 2675
Query: 2449 KGPRRP 2454
+ PR+P
Sbjct: 2676 RSPRKP 2681
Score = 42.0 bits (97), Expect = 0.009
Identities = 65/330 (19%), Positives = 115/330 (34%), Gaps = 50/330 (15%)
Query: 1791 KPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLG 1850
+PA +P+ L+ + +RS ++ +D E E + + +R
Sbjct: 162 QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSE 221
Query: 1851 A-----RERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSL 1905
+ + R+ +P + + + S P+P + ++ + R
Sbjct: 222 SESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRS 281
Query: 1906 LGTEFEYTDSESEVKVRKRSPAGLLRPKKG--LGEPGPSLAA--PTPGARGPDPSSP--D 1959
+ T + R SPA R + EPG + +P PSSP D
Sbjct: 282 AAAKTHTT----ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
Query: 1960 KAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAP 2019
K K +K K+ P GPE + L + +P P++T P
Sbjct: 338 KDK---DKKEKSATRPSPSPERSSTGPEPP---------APTPLLAERHGGSPQPLATTP 385
Query: 2020 ATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPP-----------PRAP 2068
++ P++P +A +DR P+ +K ++ PP +P
Sbjct: 386 LSQE-------PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438
Query: 2069 ALPSEARAPH-----ASSLTAAKRSKAKAK 2093
P A AP +SS T+ RS +AK
Sbjct: 439 ESPKPAPAPGSHREISSSPTSKNRSHGRAK 468
Score = 41.6 bits (96), Expect = 0.012
Identities = 103/499 (20%), Positives = 164/499 (32%), Gaps = 71/499 (14%)
Query: 2282 PDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAK 2341
PD++ + P V + S + GG + S P + R P + +
Sbjct: 1065 PDHRSDTSSPE----VRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRS--PIRQDR 1118
Query: 2342 GDRAAT--LEEG-NPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSP 2398
G+ +A+ L+ G +P + + P+ S +K A P +
Sbjct: 1119 GEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATA 1178
Query: 2399 APPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEA 2458
+PP +P P + P + L+ R P+ E SGA E+
Sbjct: 1179 SPPRQKDKFSPFPVQDRPESS-------LVFKDTLRTPPR-----ERSGAGSSPETKEQN 1226
Query: 2459 ELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWP 2518
L TS + ++ E + E+P S L S S E
Sbjct: 1227 SALP-------TSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPE------ 1273
Query: 2519 KATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGS---------SS 2569
+ + P LT + S + S + A E S +SS G S+
Sbjct: 1274 ------VEERPAVSLTLDQSQSQASLE--------AVEVPSMASSWGGPHFSPEHKELSN 1319
Query: 2570 SSSSSSSSGSETEGEEEGDKNGDGGCGTGGR-----NCSAASSRAASPASSSSSSSSSSS 2624
S +S GS E G + G N + P+ S+ SS
Sbjct: 1320 SPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSS 1379
Query: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD---EDSSCSS 2681
SSS S + + SS+ S SS + + S SSS+SS D S S
Sbjct: 1380 GHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRS 1439
Query: 2682 DDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGK----KTPAPQ--PQAPPPQPTQ 2735
++P G + + K P S G+ +P P+ PQ P P+
Sbjct: 1440 RSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRS 1499
Query: 2736 PLQPKAQAGAKSRPKKREG 2754
P P+ + ++R G
Sbjct: 1500 PSSPELNNKCLTPQRERSG 1518
Score = 40.8 bits (94), Expect = 0.020
Identities = 66/288 (22%), Positives = 103/288 (35%), Gaps = 41/288 (14%)
Query: 197 KGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQ-------EARAEG 249
+ SSSR K++ + KK R R E+S PR + E+ ++
Sbjct: 176 ESSSSRSPTPKQKKKK---------KKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
Query: 250 RQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAA 309
R+ R P ++R S ++++ P + D A ++ R ++ AA
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSAD---SASSSDTSRSRSRSAA 283
Query: 310 RQDEGARLLRRTETLLPGPR-PCPSPLPPP-PAPPKGPPAPPAAT--PAGVYTVFREQGR 365
+ L R+ + G R +P P + P +P AT P+ Y + +
Sbjct: 284 AKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKK 343
Query: 366 EHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEG 425
E P+ PS E P P A ER G P L P S P++ P
Sbjct: 344 EKSATRPS--PSPERSSTGPEP-----PAPTPLLAERHGGSPQPLATTPLSQEPVNPPSE 396
Query: 426 LR-----------EKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPA 462
EK S + PP+ PT + AS P + PA
Sbjct: 397 ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA 444
Score = 40.4 bits (93), Expect = 0.026
Identities = 154/753 (20%), Positives = 250/753 (33%), Gaps = 110/753 (14%)
Query: 1360 PGAAGAQALEKLEAAESLVLEQSFL-HGITLLSEIAELELERRSQEMGGAERALVARPSL 1418
P G + L +LEAA L H E+ LELE +E G E+ +
Sbjct: 34 PDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQ------QI 87
Query: 1419 ESLLAAGSHMLREVLDGPVVDPLKNLRLPRELKPNKKYSWMRKKEERM---YAMKSSLED 1475
+ +A ML E P + P + ++ KK ER+ + + S D
Sbjct: 88 QEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVD 147
Query: 1476 MDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDSEDRREEPHRSLARRGPGRPRKRTHA 1535
+ + R R A+ K LV R S R P + ++ R R+ +
Sbjct: 148 GSSFDPQRRAREAKQPAPEPPKPYSLV----RESSSSRSPTPKQKKKKKKKDRGRRSESS 203
Query: 1536 PSALSPPRKRGKSGHSSGKLSSKSLLTSDDYELGAGIRKRHKGSEEEHDALIGMGKARGR 1595
SP R+R KS +K+H+ E K + R
Sbjct: 204 ----SPRRERKKSSK----------------------KKKHRSESESK-------KRKHR 230
Query: 1596 NQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSAGGK 1655
+ T S D KK+ S A K +A T D S SD++ +
Sbjct: 231 SPTPKSKRKSKD--------KKRKRSRSTTPAPKSRRAHRSTSADSASS----SDTSRSR 278
Query: 1656 SKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQP 1715
S+++ K G S S R G+ E G + +P
Sbjct: 279 SRSAAA-------------KTHTTALAGRSPSPASGRRGEGDAPFS----EPGTTSTQRP 321
Query: 1716 KSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGP 1775
S + S Y D ++D++ P+ P S P + G P
Sbjct: 322 SSPETATKQPSSPYE---DKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSP 378
Query: 1776 K-LTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEE 1834
+ L L+ P A+ + E +SS S+SS S + S
Sbjct: 379 QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438
Query: 1835 ELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAA-SALPSPTVGPSLSVVQLE-A 1892
E + A G RE + SP + G R + S PS +G S S +
Sbjct: 439 ESPKPAPAPGSH-----REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRG 493
Query: 1893 KQKARKKEERQSLLGTEFEYTDSESEVKV-RKRSPAGLLRPK----------KGLGEPGP 1941
+ ++R +R ++ S S + R RSP R + + G
Sbjct: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGR 553
Query: 1942 SLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSE- 2000
S +A + P++ +++ R + R P S TRRRS
Sbjct: 554 SRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR-------RRSRSRTPTRRRSRS 606
Query: 2001 RIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGA 2060
R + + P T++ + SP + +GR++ R R+ +
Sbjct: 607 RTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARR 666
Query: 2061 GLPPPRAPALPSEARAPHASSLTAAKRSKAKAK 2093
G R PA R+ + S T A+R +++++
Sbjct: 667 GRSRSRTPA----RRSGRSRSRTPARRGRSRSR 695
Score = 39.7 bits (91), Expect = 0.045
Identities = 54/268 (20%), Positives = 86/268 (32%), Gaps = 7/268 (2%)
Query: 2515 APWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSS 2574
+P G L E G + E + P Q E D + + + S+ SSG SSS S
Sbjct: 1329 SPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSP 1388
Query: 2575 SSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSS 2634
+ E G R S R++S +S + S S S SS
Sbjct: 1389 DAV--EKAGMSSNQSISSPVLDAVPRTPSR--ERSSSASSPEMKDGLPRTPSRRSRSGSS 1444
Query: 2635 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPS 2694
S + S S S SS + S S ++ E + + P
Sbjct: 1445 PGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504
Query: 2695 AQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREG 2754
T +++G +TP Q ++P A +S
Sbjct: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPD 1564
Query: 2755 VHLPTTKELAKRQR---LPSVENRPKIA 2779
T L +R R P V+++ +++
Sbjct: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLS 1592
Score = 38.5 bits (88), Expect = 0.100
Identities = 31/150 (20%), Positives = 60/150 (40%), Gaps = 6/150 (4%)
Query: 2305 RKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLAL 2364
++ T K+ G A+ + R S+ + +++ + + S+ +
Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636
Query: 2365 EPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAP 2424
SS+ S S P P P+A P P P PP +P + + SL+
Sbjct: 2637 SSSSSSSSSSSSPSPAKP---GPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693
Query: 2425 APL-ITMPATRPKPKKARAAEESGAKGPRR 2453
+P+ P+ +P P+ +++ S +G RR
Sbjct: 2694 SPVERRRPSPQPSPRDQQSS--SSERGSRR 2721
Score = 36.6 bits (83), Expect = 0.38
Identities = 81/448 (18%), Positives = 160/448 (35%), Gaps = 64/448 (14%)
Query: 2328 KARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSK----KSPPEPVDKR 2383
+ R R R P A + R+ T + +P A+ S GS +S P +
Sbjct: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098
Query: 2384 AKAPKARPAP---------PQPSPAPPAFTSCPAP---EPFAELPAPATSLAPAPLITMP 2431
+ P +PS +P C +P EP P + L A
Sbjct: 2099 HSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQA------ 2152
Query: 2432 ATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGG 2491
GPR P DH+ + P++ L G
Sbjct: 2153 ----------GGSMMDGPGPRIP----------DHQRTSVPENHAQSRIALALTAISLGT 2192
Query: 2492 WQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFE-DSGNPKSPDKAQAE 2550
+ P S+ + G AA S+ AP P + L P L + + + + A A
Sbjct: 2193 ARPPPSMSAAGL---AARMSQVPAPVPLMS---LRTAPAANLASRIPAASAAAMNLASAR 2246
Query: 2551 QDGAEESESSSSSSSGSSSSSSSSSS-----SGSETEGEEEGDKNGDGGCGTGGRNCSAA 2605
+ + + S + +++++ + +S + S + G R +A
Sbjct: 2247 TPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAAL 2306
Query: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSS-------SSSSSSSSSSSSSSSSSSSSSSSS 2658
++ + + + + ++++ SSS + + +S S+ +++ + + S ++++ + +S
Sbjct: 2307 AALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASL 2366
Query: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDEAA--PAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
+S+ + + S ++ T S+ + + +P A++ P A Q+ A S
Sbjct: 2367 TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426
Query: 2717 PGKKT-PAPQPQAPPPQPTQPLQPKAQA 2743
P + AP PP QP P A
Sbjct: 2427 PSSRMGQAPSQSLLPPAQDQPRSPVPSA 2454
Score = 35.0 bits (79), Expect = 1.1
Identities = 45/215 (20%), Positives = 71/215 (33%), Gaps = 10/215 (4%)
Query: 927 QRSAQLVQERLKAQEHRAEMEEKGSKRGLEAA-GKAGLATAGPGLLPRKPPGLAAGPAGT 985
+RS + HR+ + S + ++ A L + P A+G G
Sbjct: 246 KRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGE 305
Query: 986 YGKAVSPPPS-----PRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPP 1040
S P + P + A + + +D K A +PS +S P P
Sbjct: 306 GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA 365
Query: 1041 PTPGITRKEEAPENVVEKKDLELEK-EAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLL 1099
PTP + + + L E PS PP+ P + P
Sbjct: 366 PTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425
Query: 1100 QPTAAADADGLAPDVPLPADGP---ERLALSPEDK 1131
QPT + +P+ P PA P ++ SP K
Sbjct: 426 QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSK 460
Score = 34.7 bits (78), Expect = 1.4
Identities = 40/163 (24%), Positives = 58/163 (35%), Gaps = 15/163 (9%)
Query: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---- 2655
R+ A R+AS +SS S S++ ++ + S S + + +SS S S S S +
Sbjct: 2070 RSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDR 2129
Query: 2656 ----------SSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATK 2705
SS + S + S D D + P ++ AL A
Sbjct: 2130 CRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAIS 2189
Query: 2706 QAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSR 2748
G ARP A Q P P P L+ A SR
Sbjct: 2190 -LGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASR 2231
Score = 33.1 bits (74), Expect = 4.2
Identities = 135/630 (21%), Positives = 212/630 (33%), Gaps = 100/630 (15%)
Query: 1523 RRGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLS----------SKSLLTSDDYELGAGI 1572
R+ P R A+ PR+R SG SS S S+S+ + E
Sbjct: 906 RQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLP 965
Query: 1573 RKRHKGSEEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDK 1632
R H GS K + H S IS K + SK
Sbjct: 966 RYSHSGSSSPDT------KVKPETPPRQSHSGS---ISPYPKVKAQTPPGPSLSGSKSPC 1016
Query: 1633 ALSLTKQDKLKS-PFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSS 1691
+K ++S P S AG KS T G + L G+++ + +S
Sbjct: 1017 PQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS------PDHRSD 1070
Query: 1692 REGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDE-EFLKDEWPAQG 1750
R + + + K++ PK S +S V+ + + +D EF G
Sbjct: 1071 TSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSG 1130
Query: 1751 --PSSSKLTPSLLCSMVAKNSKAAGGPKL----TKRGLAAP----RTLKPKPATSRKQPF 1800
P S+ ++ G +L +K +A P T P + PF
Sbjct: 1131 MSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPF 1190
Query: 1801 CL------------LLREAEARSSFSDSSEESFDQDE----SSEEEDEEEELEEEDEASG 1844
+ LR S + SS E+ +Q+ SS++E+ E +E+ +E +G
Sbjct: 1191 PVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAG 1250
Query: 1845 GGY-RLGARERALSPGLEESGLGLLARFAAS-ALPSPTVGPSLSVVQLEAKQKA----RK 1898
L + + +S ES + R A S L SL V++ + +
Sbjct: 1251 QILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHF 1310
Query: 1899 KEERQSLLGTEFEYTDSESEVKVRKRSPAG--------------LLRPKKGLGEPGPSLA 1944
E + L + S ++ R P G L P E PSL
Sbjct: 1311 SPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLD 1370
Query: 1945 APTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFL 2004
R SS + + AVEK + + P +A P +R RS
Sbjct: 1371 MKEQSTRSSGHSSSELSPDAVEKAGMSSN-QSISSPVLDAVPRTP-----SRERS----- 1419
Query: 2005 HDASAAAPAPVSTAPATKTSRCAKG---------GPLSPRKDAGRAKDRKD-PRKKKKGK 2054
+SA++P P T + R G G S +G + KD PR +G+
Sbjct: 1420 --SSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGR 1477
Query: 2055 EAGPGAGLPPPRA-PALP-SEARAPHASSL 2082
+ P P+A P P +R+P + L
Sbjct: 1478 SECDSS--PEPKALPQTPRPRSRSPSSPEL 1505
Score = 33.1 bits (74), Expect = 4.2
Identities = 30/128 (23%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 1189 TPSPAGGCGG-GLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEP--------- 1238
+P+P C G+LE S T S + + ++GP PR+ RT
Sbjct: 2123 SPTPLDRCRSPGMLEPLGSSRTPMSVLQQAG-GSMMDGPGPRIPDHQRTSVPENHAQSRI 2181
Query: 1239 --CTAALDLGVQLTPETL----VEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLE 1292
A+ LG P ++ + A+ V PV + + P LA P+ S +
Sbjct: 2182 ALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMN 2241
Query: 1293 MSDCDVPA 1300
++ PA
Sbjct: 2242 LASARTPA 2249
Score = 32.3 bits (72), Expect = 7.2
Identities = 57/272 (20%), Positives = 98/272 (36%), Gaps = 47/272 (17%)
Query: 1894 QKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLA--------- 1944
++ R + + G T + + R R+PA R + G S +
Sbjct: 654 RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS 713
Query: 1945 -APTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIF 2003
+ TP RG SS ++ + R++R + PE + +RR
Sbjct: 714 HSRTPQRRGRSGSSSERKNKSRTSQRRSRS---------NSSPEMKKSRISSRR------ 758
Query: 2004 LHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLP 2063
S + +P S A SR + LS + K + PR+ + G
Sbjct: 759 ----SRSLSSPRSKAK----SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRT 810
Query: 2064 PPRAPALPSEARAPHASSLTAAKRS-KAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFE 2122
PPR + S + P S T +++S + + +VK + G+++ A E+
Sbjct: 811 PPRR-SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT---SPQANEQSVT 866
Query: 2123 PNQDSSF--SEDEHLPRGGAVERPLTPAPRSC 2152
P + S F S D L + TP+ SC
Sbjct: 867 PQRRSCFESSPDPEL-------KSRTPSRHSC 891
Score = 32.3 bits (72), Expect = 7.2
Identities = 27/118 (22%), Positives = 47/118 (39%), Gaps = 16/118 (13%)
Query: 2290 EPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLE 2349
EP+PA KR+ R +S + ++ S + + S+ + +++
Sbjct: 2597 EPTPA------KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 2350 EGNPTDEVPSTPLALEPSSTPGSKKS--PPEPVD------KRAKAPKARPAP-PQPSP 2398
P + P A PG ++S P +P+D + +P R P PQPSP
Sbjct: 2651 PAKPGPQALPKP-ASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
Score = 32.0 bits (71), Expect = 9.4
Identities = 79/371 (21%), Positives = 119/371 (32%), Gaps = 75/371 (20%)
Query: 7 GPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAF 66
GP RS H P ++G R AA A PAS + P A L P A+
Sbjct: 2340 GP-RSAHATAPVNIAG-----SRTAAALA---PASLTSARMAPALSGANLTSPRVPLSAY 2390
Query: 67 ----------LGSFVASGMGPSASSHG----SPVPLPSDLSFRSPTPSNLPMVQLWAAHA 112
L S PSA S P PS ++P+ S LP Q
Sbjct: 2391 ERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQ------ 2444
Query: 113 HEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQ------------------LGQPSIFDT 154
+ S +PS L P +GS LS + P + +
Sbjct: 2445 DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504
Query: 155 QKGQGPGGDGFYLPTAGA---PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAG 211
G+ P G P+A A P + S+ + SS + + SSS G + +
Sbjct: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
Query: 212 RGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKT 271
P P + P +EA EGR P +R S + S +
Sbjct: 2565 GSSLPV------QPEVALKRVPSP---TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615
Query: 272 KNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPC 331
+++ S + + + + + + ++ A+ PGP+
Sbjct: 2616 SSSSSSSSSSSSSSSSSSS-------SSSSSSSSSSSSSSPSPAK---------PGPQAL 2659
Query: 332 PSPLPPPPAPP 342
P P P PP
Sbjct: 2660 PKPASPKKPPP 2670
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 109 bits (273), Expect = 4e-23
Identities = 79/235 (33%), Positives = 120/235 (51%), Gaps = 23/235 (9%)
Query: 2507 AAGSSEPKAPWPKA----TDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQ-----DGAEES 2557
++ SS+ K+ K+ +D D + + + S N S D + + D ++ S
Sbjct: 616 SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675
Query: 2558 ESSSSSSSGSSSSSSSSSSSGSETEGEEEGDK--------------NGDGGCGTGGRNCS 2603
+SSSSS S +SS SS SS S + +E + D N + + S
Sbjct: 676 DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735
Query: 2604 AASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2663
+S+ + S SS SS+SS SS SS SS+SS SS SS SS SS SS+SS S+ SS+SS SS
Sbjct: 736 DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS 795
Query: 2664 SSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPG 2718
SS+SS S+ DSS SSD + + + S+ ++ + ++ + + S S G
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG 850
Score = 109 bits (273), Expect = 4e-23
Identities = 66/146 (45%), Positives = 84/146 (57%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + + D + S+S SS SS SS SS SS+SS S + N
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + S+ SS ++ ++SS SS+SS SS S+SS SS SS+SS SS SS SS SS SS S
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S+SS SS SS SS S+ DSS SSD
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSD 1026
Score = 108 bits (271), Expect = 6e-23
Identities = 64/180 (35%), Positives = 102/180 (56%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + + + D ++ S+SS+SS S SS+SS SS S + ++ D +
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ S+ SS ++ + SS+SS SS SS SS S S SS+ S SS+SS SS SS SS+S
Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
S SS SS S+ SS+S+ DSS SSD +++ + + S+ ++ + +++ + + S S
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS 936
Score = 108 bits (271), Expect = 6e-23
Identities = 68/163 (41%), Positives = 90/163 (55%), Gaps = 1/163 (0%)
Query: 2520 ATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGS 2579
++D + + DS + + D ++ S+SS+SS S +SS SS+SS S
Sbjct: 976 SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 1035
Query: 2580 ETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSS 2639
++ + D + D + N S +S + S SS SS SS SS SS SS SS SS+SS
Sbjct: 1036 SSDSSDSSDSS-DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094
Query: 2640 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS SS SS SS SS SS SS SS SS+SS S+ DSS SSD
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137
Score = 108 bits (270), Expect = 8e-23
Identities = 66/165 (40%), Positives = 93/165 (56%), Gaps = 2/165 (1%)
Query: 2520 ATDGDLAQEPGPGLTFEDSGNPK--SPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSS 2577
+ D + + DS N S ++ D + S+SS+SS S SS+SS SS S
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844
Query: 2578 GSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSS 2637
++G + N + + S+ SS ++ + SS S+ SS+SS SS SS+SS S
Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904
Query: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS SS+SS SS SS+SS SS SS+SS +S+SS S+ DSS SSD
Sbjct: 905 SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949
Score = 108 bits (270), Expect = 8e-23
Identities = 67/145 (46%), Positives = 83/145 (57%)
Query: 2538 SGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT 2597
S N S D + + S+SS SS SS SS+SS SS S + + + D +
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Query: 2598 GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2657
+ S +S + S SS SS SS SS+SS SS+SS SS+SS SS SS SS SS SS SS
Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049
Query: 2658 SSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS SS+SS SS S+ DSS SSD
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSD 1074
Score = 108 bits (269), Expect = 1e-22
Identities = 68/158 (43%), Positives = 94/158 (59%), Gaps = 1/158 (0%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + S D + + +S+SS SS S SS SS+SS SS S ++ + D +
Sbjct: 565 DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS-SDSSDSSDSSDSSDSK 623
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + SS + S + SS S+SS SS +S SS SS+SS+SS SS SS SS SSSSS S
Sbjct: 624 SDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS 683
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPS 2694
S+SS SS SS SS+S+ DSS SSD +++ + + S
Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Score = 108 bits (269), Expect = 1e-22
Identities = 69/169 (40%), Positives = 94/169 (55%), Gaps = 6/169 (3%)
Query: 2520 ATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGS 2579
++D D + + DS + + + D ++ S+SS SS S S SS S S SS S
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636
Query: 2580 ETEGEE------EGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSS 2633
+++ + + N D + N S +S + S SSSSS SS+SS SS SS SS
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 2634 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
+SS SS SS SS S SS SS SS+S+SS S SS+SS S+ +SS SSD
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Score = 108 bits (269), Expect = 1e-22
Identities = 64/146 (43%), Positives = 86/146 (58%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + + D ++ +ESS+SS S SS+SS S SS S + N
Sbjct: 866 DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE 925
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + ++ SS +++ + SS SS SS+SS SS+SS SS+SS SS S+SS SS SS+SS S
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S SS SS SS SS S+ DSS SSD
Sbjct: 986 SDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Score = 108 bits (269), Expect = 1e-22
Identities = 69/147 (46%), Positives = 84/147 (57%), Gaps = 1/147 (0%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESS-SSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGC 2595
DS N + D +E S SS +S+SS SS+SS SS SS S + +
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 2596 GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2655
+ N S +S + S SS SS SS SS SS SS+SS SS SS SS SS+SS SS+SS
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026
Query: 2656 SSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS+SS SS SS SS S+ DSS SSD
Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSD 1053
Score = 107 bits (268), Expect = 1e-22
Identities = 62/146 (42%), Positives = 83/146 (56%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS N + D ++ S+SS+SS S SS SS+SS S ++ + D +
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ ++ S +S +S+SS SS SS SS S SS+SS SS+SS SS SS+SS SS SS
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS S S SS+ S S+ DSS SSD
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSD 872
Score = 107 bits (268), Expect = 1e-22
Identities = 66/152 (43%), Positives = 88/152 (57%), Gaps = 5/152 (3%)
Query: 2536 EDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGC 2595
E S + S D + + + +S +SS SS S+SS SS SS+ S+ + + D
Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946
Query: 2596 GTGGRNCSAAS-----SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2650
+ N S +S S ++ + S+SS SS SS+SS SS SS SS SS SS SS+SS S
Sbjct: 947 SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006
Query: 2651 SSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S SS SS SS+SS SS+SS S+ DSS SSD
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038
Score = 107 bits (268), Expect = 1e-22
Identities = 66/145 (45%), Positives = 82/145 (56%)
Query: 2538 SGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT 2597
S + S D + + + +S +SS SS S SS SS SS S + + + D +
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Query: 2598 GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2657
N S +S+ + S SS SS SS SS SS SS SS+SS SS SS SS SS SS SS SS
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Query: 2658 SSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS SS SS SS+S+ DSS SSD
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSD 1104
Score = 107 bits (268), Expect = 1e-22
Identities = 68/165 (41%), Positives = 89/165 (53%), Gaps = 2/165 (1%)
Query: 2520 ATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGS 2579
++D + + DS N + D ++ S+SS SS S SS SS+SS S
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 2580 ETEGEEEGDKN--GDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSS 2637
++ + D + D + + S +S+ + S SS SS SS SS SS SS SS SS+
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Query: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS SS SS SS SS SS+SS SS SS SS SS S+ DSS SSD
Sbjct: 1123 SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD 1167
Score = 107 bits (268), Expect = 1e-22
Identities = 68/151 (45%), Positives = 83/151 (54%), Gaps = 5/151 (3%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKN-----G 2591
DS N + D ++ S+SS SS S SS SS SS+S ++ + D +
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112
Query: 2592 DGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2651
D + N S +S + S SS SS+SS SS SS SS SS SS SS SS SS SS SS
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172
Query: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS SS+SS SS SS SS S+ DSS SSD
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203
Score = 107 bits (267), Expect = 2e-22
Identities = 67/185 (36%), Positives = 105/185 (56%), Gaps = 2/185 (1%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + S D + + + +S+SS+SS S SS+SS SS S + + D +
Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN-- 763
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + S+ SS ++ ++SS S+ SS+SS SS SS+SS SS+SS SS SS SS S SS+S
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
S SS+SS SS SS+S+ DSS SSD + + S+ ++ + ++ + + S S
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883
Query: 2717 PGKKT 2721
++
Sbjct: 884 DSNES 888
Score = 107 bits (267), Expect = 2e-22
Identities = 66/170 (38%), Positives = 98/170 (57%), Gaps = 7/170 (4%)
Query: 2520 ATDGDLAQEPGPGLTFEDSGNPKSPDKAQA-------EQDGAEESESSSSSSSGSSSSSS 2572
++D D + + + S + S D + + + D + S+SS+SS S SS SS
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS 874
Query: 2573 SSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSS 2632
+SS S ++ E + + + S+ SS ++ + SS+SS SS SS+SS +S+
Sbjct: 875 NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934
Query: 2633 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS SS+SS SS SS SS+SS SS+SS SS+SS SS S+S+ DSS SSD
Sbjct: 935 SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984
Score = 107 bits (267), Expect = 2e-22
Identities = 65/146 (44%), Positives = 84/146 (57%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + + + D E S SS SS S +SS S SS SS S + +
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + S+ SS ++ + SS SS+SS SS+SS SS+SS SS S+SS SS SS+SS SS S
Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDS 988
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S SS SS SS SS+S+ DSS SSD
Sbjct: 989 SDSSDSSDSSDSSNSSDSSDSSDSSD 1014
Score = 107 bits (267), Expect = 2e-22
Identities = 67/163 (41%), Positives = 89/163 (54%)
Query: 2520 ATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGS 2579
++D + E DS N D + + S+SS SS SS+SS +S+SS S
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 2580 ETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSS 2639
+ + + + S+ SS ++ SS SS SS+SS SS SS SS SS SS
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 2640 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS+SS SS SS SS SS+SS SS+SS SS+S+ DSS SSD
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Score = 107 bits (266), Expect = 2e-22
Identities = 66/192 (34%), Positives = 104/192 (54%)
Query: 2507 AAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSG 2566
++ SS+ ++ D + + + S + +S D + + + +S SS+S+S
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724
Query: 2567 SSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSS 2626
S SS+SS SS S + + + + S+ SS ++ + SS SS SS+SS
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784
Query: 2627 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAA 2686
S+ SS+SS SS SS+SS SS+SS SS SS SS S SS+SS SS+S+ DSS SSD +
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844
Query: 2687 PAPTAGPSAQAA 2698
+ G + ++
Sbjct: 845 SDSSDGSDSDSS 856
Score = 107 bits (266), Expect = 2e-22
Identities = 66/149 (44%), Positives = 91/149 (61%), Gaps = 2/149 (1%)
Query: 2536 EDSGNPKSPDKAQAEQ--DGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDG 2593
+ S + S D + + + + ++ S+SS+SS S SS SS+SS SS S + N
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Query: 2594 GCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2653
+ + S+ SS ++ ++SS SS+SS SS+SS SS S+SS SS SS+SS SS SS S
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991
Query: 2654 SSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S SS SS SS+SS SS S+ DSS SSD
Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Score = 107 bits (266), Expect = 2e-22
Identities = 68/180 (37%), Positives = 99/180 (55%), Gaps = 2/180 (1%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS N ++ D + S+SS+SS S SS SS+SS S + ++ D +
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + S+ SS ++ SS SS SS SS+SS SS SS SS SS+SS SS+SS SS+SS S
Sbjct: 976 SSDSSNSSDSSDSSD--SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
S SS SS SS SS S+ DSS SSD + + + + + + ++ + S++S
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093
Score = 107 bits (266), Expect = 2e-22
Identities = 67/176 (38%), Positives = 91/176 (51%)
Query: 2507 AAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSG 2566
++ SS+ + D + + + S + S + + + + +S SS+SS
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985
Query: 2567 SSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSS 2626
S SS SS SS S++ + + D + + S +S + S SS SS SS SS S
Sbjct: 986 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1045
Query: 2627 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S SS SS SS+SS SS SS SS SS SS SS SS SS SS SS S+ DSS SSD
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101
Score = 107 bits (266), Expect = 2e-22
Identities = 67/146 (45%), Positives = 83/146 (56%), Gaps = 2/146 (1%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + S D + + + +S SS SS S SS SS+SS S++ + + D
Sbjct: 967 DSSDSNSSDSS--DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ N S +S + S SS SS SS SS SS+SS SS SS SS SS SS SS SS SS S
Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSES 1084
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S SS SS+SS SS S+ DSS SSD
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSDSSD 1110
Score = 106 bits (265), Expect = 3e-22
Identities = 62/162 (38%), Positives = 91/162 (56%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DSG KS D + S+SS SS S SS S+SSS S S+++ + D +
Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSN 600
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + S+ SS ++ + SS S S SS S S SS S S S SS S+SS SS +S SS SS
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAA 2698
+SS+SS SS SS SS + S S+ +++ + + S++++
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702
Score = 106 bits (265), Expect = 3e-22
Identities = 68/167 (40%), Positives = 90/167 (53%), Gaps = 4/167 (2%)
Query: 2520 ATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSS----SSGSSSSSSSSS 2575
++D + + D+ N + D ++ S SS SS SS SS SS S+S
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 2576 SSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSS 2635
S S++ + + D + + S +S + S SS SS+SS SS+SS SS+SS S
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 2636 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S SS SS SS SS SS SS SS+SS SS SS SS S+ DSS SSD
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Score = 106 bits (265), Expect = 3e-22
Identities = 67/151 (44%), Positives = 84/151 (55%), Gaps = 5/151 (3%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGD-----KNG 2591
DS N + D ++ S+SS SS S +SS SS SS S ++ + D ++
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Query: 2592 DGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2651
D + + S +S + S SS SS SS SS SS+SS SS SS SS SS SS+SS SS
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS SS SS SS SS SS S+ DSS SSD
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSSDSSDSSD 1176
Score = 106 bits (265), Expect = 3e-22
Identities = 73/212 (34%), Positives = 107/212 (50%), Gaps = 2/212 (0%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + + D +E S+SS SS+S SS SS SS S ++ + D + D
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS-DSSNS 1123
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + S +S + S SS SS SS SS SS SS SS SS SS SS SS SS SS+SS S
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSD-DEAAPAPTAGPSAQAALPTKATKQAGKARPSAH 2715
S SS SS SS SS S+ DSS SSD +++ + + S+ ++ + + + + + S
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243
Query: 2716 SPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKS 2747
S + + T ++ + +KS
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275
Score = 106 bits (264), Expect = 4e-22
Identities = 69/179 (38%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
Query: 2520 ATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGS 2579
++D + + + S + S D ++ D ++ S+S SS SS SS SS SS SS S
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613
Query: 2580 ETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSS----SSSSSSSSSSSSSSSSSS 2635
+ K+ + + + S + S +S SS SS SS+SS+SS SS SS
Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD 673
Query: 2636 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPS 2694
SS SSSSS SS+SS SS SS SS+SS SS SS SS + DSS SS+ ++ + ++ S
Sbjct: 674 SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Score = 106 bits (264), Expect = 4e-22
Identities = 66/180 (36%), Positives = 101/180 (56%), Gaps = 1/180 (0%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + D + D + S+SS SS S +SS SS SS S + + D +
Sbjct: 846 DSSDGSDSDSSN-RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + S+ SS +++ + SS SS+SS +S+SS SS+SS SS SS SS+SS SS+SS SS+
Sbjct: 905 SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
SS SS S+SS SS S+ DSS SSD + + ++ + + + + + S++S
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024
Score = 105 bits (263), Expect = 5e-22
Identities = 67/180 (37%), Positives = 102/180 (56%), Gaps = 1/180 (0%)
Query: 2538 SGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT 2597
S + S D ++ + + +S+SS S SS SS S SS SS+ S++ + + D +
Sbjct: 561 SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS 620
Query: 2598 GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2657
++ S+ S +S + S S SS S+SS SS +S SS SS+SS+SS SS SS SS SSSS
Sbjct: 621 DSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 2658 S-SSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
S SS+SS SS SS S+ +SS SSD + + + S+ + + + + S++S
Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740
Score = 105 bits (263), Expect = 5e-22
Identities = 67/165 (40%), Positives = 95/165 (57%), Gaps = 3/165 (1%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSS--GSSSSSSSSSSSGSETEGEEEGDK-NGDG 2593
DS N + D + S+SS SS S GS S SS+ S S + ++ + D N
Sbjct: 819 DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878
Query: 2594 GCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2653
+ N S+ SS ++ ++SS S SS SS+SS SS SS+SS SS SS+SS +S+SS S
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 2654 SSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAA 2698
S+SS SS SS SS+SS S+ DSS SSD + + + S+ ++
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Score = 105 bits (262), Expect = 7e-22
Identities = 66/147 (44%), Positives = 84/147 (57%), Gaps = 1/147 (0%)
Query: 2537 DSGNPKSPDKAQA-EQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGC 2595
DS + S D + + + + +S SS SS S+SS SS SS S++ + + D
Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029
Query: 2596 GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2655
+ + S +S + S SS SS SS+SS SS SS SS SS SS SS SS SS SS SS
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089
Query: 2656 SSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS+SS SS SS SS S+ DSS SSD
Sbjct: 1090 SSNSSDSSDSSDSSDSSDSSDSSDSSD 1116
Score = 105 bits (262), Expect = 7e-22
Identities = 66/158 (41%), Positives = 84/158 (53%), Gaps = 2/158 (1%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKN--GDGG 2594
DS N + D ++ S SS SS S SS SS SS S ++ + D + D
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 2595 CGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2654
+ + S +S + S SS SS SS SS SS SS SS SS SS SS SS S+ SS SS
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Query: 2655 SSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG 2692
SS SS SS+SS SS S+ DS+ S+DE+ +G
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSG 1276
Score = 105 bits (261), Expect = 9e-22
Identities = 71/191 (37%), Positives = 95/191 (49%), Gaps = 8/191 (4%)
Query: 2500 SLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESES 2559
S S + +S + ++D + + DS N + D + S+S
Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021
Query: 2560 SSSSSSGSSSSSSSSSSSGSETEGEEEGDKN--------GDGGCGTGGRNCSAASSRAAS 2611
S+SS S +SS SS SS S ++ + D + D + + S +S + S
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081
Query: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
SS SS SS+SS SS SS SS SS SS SS SS SS SS+SS SS SS SS SS SS+S
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 1141
Query: 2672 TTDEDSSCSSD 2682
+ DSS SSD
Sbjct: 1142 SDSSDSSESSD 1152
Score = 104 bits (260), Expect = 1e-21
Identities = 67/175 (38%), Positives = 90/175 (51%)
Query: 2508 AGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGS 2567
+ SS+ + D + + + S + S D ++ + S SS SS S
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Query: 2568 SSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSS 2627
SS SS SS+ S++ + + + + + S +S + S SS SS SS SS SS
Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052
Query: 2628 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS+SS SS SS SS SS SS SS SS SS SS SS SS+SS S+ DSS SSD
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107
Score = 104 bits (260), Expect = 1e-21
Identities = 66/146 (45%), Positives = 81/146 (55%), Gaps = 1/146 (0%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + + D ++ S+SS SS S SS SS SS S + + D + D
Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS-DSSDS 1105
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + S +S + S SS SS SS SS SS SS+SS SS SS SS SS SS SS SS S
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S SS SS SS SS+S+ DSS SSD
Sbjct: 1166 SDSSDSSDSSDSSNSSDSSDSSDSSD 1191
Score = 104 bits (259), Expect = 1e-21
Identities = 65/147 (44%), Positives = 87/147 (59%), Gaps = 1/147 (0%)
Query: 2536 EDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGC 2595
+ S + S D + ++ D ++ SES SS S S SS S+SS S+ + + +
Sbjct: 609 DSSDSSDSSDSSDSKSDSSK-SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSD 667
Query: 2596 GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2655
+ + S +SS + S SS SS SS SS+SS SS SS SS S SS SS SS+S+SS S
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727
Query: 2656 SSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS+SS SS SS+SS S+ DSS SSD
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSD 754
Score = 103 bits (258), Expect = 2e-21
Identities = 65/147 (44%), Positives = 86/147 (58%), Gaps = 1/147 (0%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDK-NGDGGC 2595
DS + + + + ++ SESS+SS + +SS SS+SS S ++ D N
Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963
Query: 2596 GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2655
+ + S +S + S SS SS SS SS SS SS SS+SS SS SS SS SS+SS SS+
Sbjct: 964 NSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSN 1023
Query: 2656 SSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS SS+SS SS SS S+ DSS SSD
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSD 1050
Score = 103 bits (258), Expect = 2e-21
Identities = 66/146 (45%), Positives = 80/146 (54%), Gaps = 1/146 (0%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
DS + + D + S+SS SS S SS SS SS S +E + D +
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD-S 1096
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ + S +S + S SS SS SS+SS SS SS SS SS SS+SS SS SS SS SS S
Sbjct: 1097 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDS 1156
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S SS SS SS SS S+ DSS SSD
Sbjct: 1157 SDSSDSSDSSDSSDSSDSSDSSNSSD 1182
Score = 102 bits (253), Expect = 7e-21
Identities = 66/173 (38%), Positives = 94/173 (54%), Gaps = 15/173 (8%)
Query: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSS--SSSSSSSSSGSETEGEEEGDK-------- 2589
+P S D++ D ES+++SSS +S S S + +GS+++G E+ D
Sbjct: 464 DPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Query: 2590 -----NGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
NG+ G ++ S +S + SS SS+SS SS SS S SS S+SSS S SS
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583
Query: 2645 SSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQA 2697
S SS SS S SS SS+SS SS SS S+ DSS SSD ++ + + S+ +
Sbjct: 584 DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636
Score = 94.7 bits (234), Expect = 1e-18
Identities = 58/158 (36%), Positives = 85/158 (53%), Gaps = 12/158 (7%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGS------------SSSSSSSSSSGSETEGE 2584
D N +S + + + D + S+ S + +GS +S +++S S+G+ G
Sbjct: 475 DDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGN 534
Query: 2585 EEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
++ DK+ G + + ++ S +S +S SS S SS S+SSS S SS S SS SS S
Sbjct: 535 DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594
Query: 2645 SSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
SS SS+SS SS SS SS SS SS SS + + S SD
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Score = 92.8 bits (229), Expect = 4e-18
Identities = 65/180 (36%), Positives = 92/180 (51%), Gaps = 18/180 (10%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
++GN + DK+ + + ++ S+S SS SS SS SS SS S S++ + D
Sbjct: 531 NNGNDDN-DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD-------- 581
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
SS + S SS S SS SS+SS SS SS SS SS SS SS S S SS S S
Sbjct: 582 ---------SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
SS S S S SS S+S+ D+S SSD + + + + + ++ + + S+ S
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692
Score = 87.0 bits (214), Expect = 2e-16
Identities = 54/179 (30%), Positives = 92/179 (51%), Gaps = 9/179 (5%)
Query: 2528 EPGPGLTFEDSGNPKSPDKAQA--------EQDGAEESESSSSSSSGSSSSSSSSSSSGS 2579
EPG + ++G+ + D + + D S+ S+ + +S S ++SSS G
Sbjct: 431 EPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGD 490
Query: 2580 ETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSS 2639
+ +E NG+G G + + S + + S S+ + ++ + + S S S S
Sbjct: 491 ASYNSDESKDNGNGSDSKGAED-DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDS 549
Query: 2640 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAA 2698
S S SS SS+SS SS SS S SS S+SSS S ++D DSS SSD +++ + + S+ ++
Sbjct: 550 SDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608
Score = 60.5 bits (145), Expect = 2e-08
Identities = 58/252 (23%), Positives = 107/252 (42%), Gaps = 18/252 (7%)
Query: 2439 KARAAEESGAKGPRRPGEEA-ELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKS 2497
K +EE+ A P G + E KL+H +SK+ + + + A G + K
Sbjct: 321 KTSKSEENSAGIPEDNGSQRIEDTQKLNHR-----ESKRVENRITKESETHAVGKSQDKG 375
Query: 2498 LLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEES 2557
+ G P++G+ K +G ++ G GN K+ + + ++S
Sbjct: 376 IEIKG---PSSGNRNITKEVGKGNEGK--EDKGQHGMILGKGNVKTQGEVVNIEGPGQKS 430
Query: 2558 ESSSS---SSSGSSSSSSSSSSSGSETEGEEEGDKNG----DGGCGTGGRNCSAASSRAA 2610
E + S++GS S+S S + + + D N +G + + +SSR
Sbjct: 431 EPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGD 490
Query: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670
+ +S S + + S S + S S+S +++S S+ + ++ + + S S S SS
Sbjct: 491 ASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSS 550
Query: 2671 STTDEDSSCSSD 2682
+ DSS SSD
Sbjct: 551 DSDSSDSSNSSD 562
Score = 35.8 bits (81), Expect = 0.65
Identities = 43/236 (18%), Positives = 93/236 (39%), Gaps = 16/236 (6%)
Query: 2553 GAEESESSSSSSSGSSSSSSSSSSSGSETEGE-EEGDKNGDGGCGTGGRNCSAASSRAAS 2611
G EE+ +++ S ++ +++ S T G ++ +NGD G G N A +
Sbjct: 126 GKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGD--VGDAGHNEDVAVVQEDG 183
Query: 2612 PASSSSSSSSSS------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665
P + S++S+ + +S + ++S + +S + + + + + + +S
Sbjct: 184 PQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSD 243
Query: 2666 SSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQ 2725
S S + DED S D+ G + + + GK S G+ + + +
Sbjct: 244 GSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKE 303
Query: 2726 ------PQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENR 2775
+ P + K++ + P+ + T++L R+ VENR
Sbjct: 304 YYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRES-KRVENR 358
Score = 35.0 bits (79), Expect = 1.1
Identities = 31/168 (18%), Positives = 53/168 (31%), Gaps = 9/168 (5%)
Query: 2522 DGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSET 2581
D + QE GP + S N + E E +S + +S + + + +
Sbjct: 175 DVAVVQEDGPQVA--GSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPG 232
Query: 2582 EGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641
GE+ G N DG G + S + + SS++S
Sbjct: 233 TGEDAGLDNSDGSPSGNGAD-------EDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDH 285
Query: 2642 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAP 2689
SS +S S + D D + S++ +A P
Sbjct: 286 GKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIP 333
Score = 32.3 bits (72), Expect = 7.2
Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 17/68 (25%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSS-----------------SGS 2579
DS + +++ D ++ S+SS+SS S SS SS S+S +GS
Sbjct: 1224 DSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGS 1283
Query: 2580 ETEGEEEG 2587
+++ + EG
Sbjct: 1284 DSDSDSEG 1291
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 96.7 bits (239), Expect = 3e-19
Identities = 93/319 (29%), Positives = 132/319 (41%), Gaps = 38/319 (11%)
Query: 2510 SSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSS---SSSG 2566
+SE K P P + +P + G P + + E+ G + + S S G
Sbjct: 906 ASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEG 965
Query: 2567 SSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSS 2626
+S SSS E + E+E D++ + T + S S
Sbjct: 966 EEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEV--------------SDGEDEES 1011
Query: 2627 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAA 2686
SSS S + S + S+S S SSSSSSSSSSSSSSSSSSSSSS+++ S S D+E
Sbjct: 1012 DSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSE---SSSEDEEEE 1068
Query: 2687 PAPTAGPSA-----QAALPTKATKQAGKARPSAHSPGKKTP----------APQPQAPPP 2731
P A PSA + +PT A + A SP P P ++PP
Sbjct: 1069 ERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPS 1128
Query: 2732 QPTQPLQPKAQAGAKS-RPKKREGVHLPTTKELAKRQRLPSVENRPKIAA--FLPARQLW 2788
P +P +P A A + RP +R +P KR++ S + A PA
Sbjct: 1129 APLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQ 1188
Query: 2789 KWFGKPTQRRGMKGKARKL 2807
F P R+ +G R +
Sbjct: 1189 AKFPGPASRKAPRGVERTI 1207
Score = 67.0 bits (162), Expect = 3e-10
Identities = 61/237 (25%), Positives = 108/237 (45%), Gaps = 11/237 (4%)
Query: 2508 AGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGS 2567
+G++ A + + D A P GN + + +++ SS +
Sbjct: 207 SGAATETAESRRRSSSDTAAYPAGTTAVGTPGNGTPCSQDTSFSSSRQDTPSSFGQFTPQ 266
Query: 2568 SSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSS 2627
SS + +S GS ++ + R + A S S+SS+S+++S++
Sbjct: 267 SSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTTASTA 326
Query: 2628 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--------SSSSSTTDEDSSC 2679
++++++++SSS+SSSS SSSSSSSSSSSSS SS ++ + T
Sbjct: 327 IAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRR 386
Query: 2680 SSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQP 2736
++ +E AP A +A+ P+ + PS + P P +APPP+P +P
Sbjct: 387 ATREEPPGAPFAENTAERFPPSYTSYL--PPEPSRPTDQDYRP-PASEAPPPEPPEP 440
Score = 59.7 bits (143), Expect = 4e-08
Identities = 76/288 (26%), Positives = 99/288 (34%), Gaps = 54/288 (18%)
Query: 2339 KAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSP 2398
+ G L E + P+ P P S P PP A P RP+ P P
Sbjct: 1099 RVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLL 1158
Query: 2399 APP----------AFTSCPAPE------PFAELPAPATSLAP---------APLITMPAT 2433
PP A PAPE P A+ P PA+ AP PL
Sbjct: 1159 PPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDHASLV 1218
Query: 2434 RPKPKKARAAEESGAKGPRR--------PGEEAELLVKLDHEGVTSPKSKKAKEALLLRE 2485
+ P++ S A G R PG E +L V D + +++ AL E
Sbjct: 1219 KSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAVLAD---LALTPARRGLPALPAVE 1275
Query: 2486 DPGA----GGWQEPKSLLS-----------LGSYPPAAGSSEPK-APWPKATDGDLAQE- 2528
D A + P+ LLS + PPA P+ P P A A E
Sbjct: 1276 DSEATETSDEAERPRPLLSHILLEHNYALAVKPTPPAPALRPPEPVPAPAALFSSPADEV 1335
Query: 2529 -PGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSS 2575
P + ++ PK Q ++G EE E SS SSSSS
Sbjct: 1336 LEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSS 1383
Score = 59.3 bits (142), Expect = 5e-08
Identities = 85/336 (25%), Positives = 114/336 (33%), Gaps = 85/336 (25%)
Query: 2434 RPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQ 2493
R +P + A E P P EE E ++ KEA +PG G +
Sbjct: 897 RKEPSEISEASEEKRPRPSTPAEEDE------------DDPEQEKEA----GEPGRPGTK 940
Query: 2494 EPKSLLSLGSYPP------AAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKA 2547
PK G A S +A +++ D ++ ED K
Sbjct: 941 PPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKD-EEDDEEDEEDEDREEAVDTTKK 999
Query: 2548 QAEQDGAEESESSSSS-----------SSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG 2596
+ E E+ ES SSS + +S S SSSSSS
Sbjct: 1000 ETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSS------------------- 1040
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+SSSSSSSSSSSSSSSSS SSS ++ S+S
Sbjct: 1041 ----------------SSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREV 1084
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
+ + + + EA+PA AG PT+ + + RP
Sbjct: 1085 PVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAG-------PTEESPPSAPLRPPEPP 1137
Query: 2717 PGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKR 2752
G PAP+P P P L P PKKR
Sbjct: 1138 AGPPAPAPRPDERPSSPIPLLPP---------PKKR 1164
Score = 57.4 bits (137), Expect = 2e-07
Identities = 64/243 (26%), Positives = 100/243 (41%), Gaps = 41/243 (16%)
Query: 2548 QAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKN-GDGGCGTG-GRNCSAA 2605
Q G + S ++ ++ S S S+T G G G GT ++ S +
Sbjct: 191 QTVPTGGKALSEKFQGSGAATETAESRRRSSSDTAAYPAGTTAVGTPGNGTPCSQDTSFS 250
Query: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSSSSSS--------------- 2648
SSR +P+S + SS + +S S+ S S+ SSS++S+S
Sbjct: 251 SSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDAFS 310
Query: 2649 ----SSSSSS--------------SSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPT 2690
S+SS+S +SSS+SSSS SSSSSSS++ S S D PA
Sbjct: 311 RRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYY 370
Query: 2691 AG----PSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAK 2746
+ P +AT++ P A + ++ P PP+P++P + A
Sbjct: 371 ESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPAS 430
Query: 2747 SRP 2749
P
Sbjct: 431 EAP 433
Score = 47.0 bits (110), Expect = 3e-04
Identities = 88/381 (23%), Positives = 140/381 (36%), Gaps = 77/381 (20%)
Query: 1767 KNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFS-DSSEESFDQDE 1825
+ K AG P P T PK R + + + R SF+ DS E Q+
Sbjct: 926 EQEKEAGEP-------GRPGTKPPKRDEERGKT------QGKHRKSFALDSEGEEASQES 972
Query: 1826 SSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSL 1885
SSE+++E++E +EEDE +E +S G +E + +L + + G +
Sbjct: 973 SSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEES----DSSSKCSLYADSDGEND 1028
Query: 1886 SVVQLEAKQKARKKEERQSLLGTEFEYTDSE--SEVKVRKRSPAGL---LRPKKGLGEPG 1940
S E+ + S + + SE SE + + PA L P + + P
Sbjct: 1029 STSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPT 1088
Query: 1941 PS-LAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRS 1999
P+ + P P P +P L ++ AR P P E+ P A
Sbjct: 1089 PAPVEVPVPERVAGSPVTP----LPEQEASPAR----PAGPTEESPPSAP---------- 1130
Query: 2000 ERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPG 2059
+ + A PAP +S PL P P+K++K
Sbjct: 1131 --LRPPEPPAGPPAPAPRPDERPSSPI----PLLP-----------PPKKRRKTVSFSAI 1173
Query: 2060 AGLPPPR-APALPSEARAPHASSLTAAK-------------RSKAKAKGKEVKKENRGKG 2105
+P P PA P +A+ P +S A + S K+ +EV + R +
Sbjct: 1174 EVVPAPEPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRA 1233
Query: 2106 GAVSKLMESMAAEEDFEPNQD 2126
G +L E EE+ EP +
Sbjct: 1234 GGRGRLTE----EEEAEPGTE 1250
Score = 46.6 bits (109), Expect = 4e-04
Identities = 53/245 (21%), Positives = 84/245 (34%), Gaps = 30/245 (12%)
Query: 2505 PPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSS 2564
PPA+ + P+ P P G G G + E SP A + G+ E+++ S
Sbjct: 427 PPASEAPPPEPPEPGGGGG------GGGPSPEREEVRTSPRPASPARSGSPAPETTNESV 480
Query: 2565 SGSSSSSSSS-------------SSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAAS 2611
+ SS S S S+TE EEE G TG S + +
Sbjct: 481 PFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCT 540
Query: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
P + ++ + + S ++ S ++ + +S SS S S + +
Sbjct: 541 PPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTP 600
Query: 2672 TTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPP 2731
P P P A+LP +P+ P + P P+ PPP
Sbjct: 601 P-------QQPPPPPPPPPPPPPYLASLPLGYPPH----QPAYLLPPRPDGPPPPEYPPP 649
Query: 2732 QPTQP 2736
P P
Sbjct: 650 PPPPP 654
Score = 45.1 bits (105), Expect = 0.001
Identities = 95/441 (21%), Positives = 140/441 (31%), Gaps = 42/441 (9%)
Query: 2321 GSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPE-P 2379
GSE P G P A A + A G P S + ++P S E
Sbjct: 527 GSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEIS 586
Query: 2380 VDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPF-AELPAPATSLAPAPLITMPATRPKPK 2438
D R +P P PPQ P PP P P P+ A LP PA L+ P P
Sbjct: 587 DDDRGGSPPPAPTPPQQPPPPP--PPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPP- 643
Query: 2439 KARAAEESGAKGPRRPG-----EEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQ 2493
E P P EL+ +L + P S + + +L R +
Sbjct: 644 -----PEYPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTR----LHQLR 694
Query: 2494 EPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDG 2553
+ K L++ + PP E P+P QE GL P + E G
Sbjct: 695 QGKGLIAASAGPPGGAFGEAFLPFPP------PQEAAYGL-------PYALYAQGQEGRG 741
Query: 2554 AEESESSSSSSSGSSSSSSSSSSSGSET-----EGEEEGDKNGDGGCGTGGRNCSAASSR 2608
A E+ ++ SSS SG E E E + GT GR +
Sbjct: 742 AYSREAYHLPMPMAAEPLPSSSVSGEEARLPPREEAELAEGKTLPTAGTVGRVLAMLVQE 801
Query: 2609 AASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668
S + + + + S + +++ + +
Sbjct: 802 MKS--IMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAKQQAKEEDKEKTKLKEPG 859
Query: 2669 SSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQA 2728
S D S + A A +G LP+ K + PS S + P+P
Sbjct: 860 LLSLVDWAKSGGTTGIEAFAFGSGLRGALRLPSFKVK---RKEPSEISEASEEKRPRPST 916
Query: 2729 PPPQPTQPLQPKAQAGAKSRP 2749
P + + + +AG RP
Sbjct: 917 PAEEDEDDPEQEKEAGEPGRP 937
Score = 44.7 bits (104), Expect = 0.001
Identities = 44/178 (24%), Positives = 65/178 (36%), Gaps = 15/178 (8%)
Query: 2575 SSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSS 2634
+S E E G G GG + R S R ASPA S S + +++ S + SS
Sbjct: 429 ASEAPPPEPPEPGGGGGGGG-PSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSS 487
Query: 2635 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPS 2694
S S S +S + +SS + T + S P A +
Sbjct: 488 LDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPAN 547
Query: 2695 AQAALPTKATKQAGKARPSAHSPGKKTPAP-------------QPQAPPPQPTQPLQP 2739
+ PT + + G R S + G+ +P + +PPP PT P QP
Sbjct: 548 FEDVAPT-GSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQP 604
Score = 43.1 bits (100), Expect = 0.004
Identities = 49/185 (26%), Positives = 67/185 (36%), Gaps = 24/185 (12%)
Query: 2579 SETEGEEEGDKNGDGGCG--TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSS 2636
SE E + G GG G + R S R ASPA S S + +++ S + SS
Sbjct: 430 SEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLD 489
Query: 2637 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQ 2696
S S S +S + +SS + T + S P A + +
Sbjct: 490 SRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFE 549
Query: 2697 AALPTK-----ATKQAGKAR-PSAHSP---------------GKKTPAPQP-QAPPPQPT 2734
PT AT+++ KA + SP G PAP P Q PPP P
Sbjct: 550 DVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPP 609
Query: 2735 QPLQP 2739
P P
Sbjct: 610 PPPPP 614
Score = 41.6 bits (96), Expect = 0.012
Identities = 85/385 (22%), Positives = 128/385 (33%), Gaps = 68/385 (17%)
Query: 298 AEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVY 357
+ + + E++ +DE LP P P +P P P P P + V
Sbjct: 1050 SSSSSSSSSESSSEDEEEE---ERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPV- 1105
Query: 358 TVFREQGREHRVVAPTFVPSVEAFDERP-GPIQIASQARDARAREREAGRPGVLQAP--- 413
T +P EA RP GP + + + R E AG P P
Sbjct: 1106 ---------------TPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDER 1150
Query: 414 PGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEAD-P 472
P SP PL P R K +++ P +P+P P P+A P
Sbjct: 1151 PSSPIPLLPPPKKRRKTVSFSAIEVVP------------APEPPPATP------PQAKFP 1192
Query: 473 RPCER-APRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHH 531
P R APRG ++ + L+ + PE E+ ++
Sbjct: 1193 GPASRKAPRG-----VERTIRNLPLDHASLVKSWPE------EVSRGGRSRAG------G 1235
Query: 532 HSRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKY 591
R EE + A L A+ P P + A S EA + L+ +
Sbjct: 1236 RGRLTEEEEAEPGTEVDLAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSH 1295
Query: 592 SGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQL 651
A+AV+P P L +P PAP + +S A L P
Sbjct: 1296 ILLEHNYALAVKP-----TPPAPALRPPEPVPAPAALFSSPADEVLE---APEVVVAEAE 1347
Query: 652 KRDPERPESAKAFGREGSGAQGEAE 676
+ P++ + + G E +GE E
Sbjct: 1348 EPKPQQLQQQREEGEEEGEEEGEEE 1372
Score = 40.0 bits (92), Expect = 0.034
Identities = 47/173 (27%), Positives = 64/173 (36%), Gaps = 19/173 (10%)
Query: 292 GLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAA 351
GLPAL A ++ DE R +L + P PPAP PP P A
Sbjct: 1267 GLPALPAVED---SEATETSDEAERPRPLLSHILLEHNYALAVKPTPPAPALRPPEPVPA 1323
Query: 352 TPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQ 411
PA +++ ++ E V V A E P P Q+ Q + E G +
Sbjct: 1324 -PAALFSSPADEVLEAPEV-------VVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEE 1375
Query: 412 APPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKE 464
+ S D LR ++ + +R PP P P PRAY P E
Sbjct: 1376 SSDSSSSS-DGEGALRRRSLRSHARRRRPPPPPP-------PPPPRAYEPRSE 1420
Score = 36.6 bits (83), Expect = 0.38
Identities = 107/472 (22%), Positives = 150/472 (31%), Gaps = 82/472 (17%)
Query: 948 EKGSKRGLEAAGKAGLATAGPGL----LPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAA 1003
E S+ E A L +A P +P P P G V+P P ASP
Sbjct: 1059 ESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPAR- 1117
Query: 1004 LKAKVIQKLEDVSKPPAYAYPATPSSHPTSPP-PASPPPTPGITRKEEAPENVVEKKDLE 1062
PA +P S P PP P + PP P R +E P + +
Sbjct: 1118 ---------------PAGPTEESPPSAPLRPPEPPAGPPAPA-PRPDERPSSPIPLLPPP 1161
Query: 1063 LEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPE 1122
++ F A+ +P P A PP P P
Sbjct: 1162 KKRRKTVSFSAI-EVVPAPEPPPATPPQAKFPGP------------------------AS 1196
Query: 1123 RLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLP 1182
R A ++ IR P ++ PEE R + E P E L +
Sbjct: 1197 RKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAV- 1255
Query: 1183 AAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAA 1242
A+ TP+ G AL A S E +E D E P P + S E A
Sbjct: 1256 LADLALTPARRG--------LPALPAVEDS--EATETSDEAERPRPLL-SHILLEHNYA- 1303
Query: 1243 LDLGVQLTPETLVEAKEEPVEVPVAV---PVVEAVPEEGLAQVAPSESQPTLEMSDCDVP 1299
L V+ TP EPV P A+ P E + + E +P +
Sbjct: 1304 --LAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEG 1361
Query: 1300 AGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPS 1359
EG+ E EE SSD S D + + + + RP P
Sbjct: 1362 EEEGEEEGEEE-------------EEESSDS--SSSSDGEGALRRRSLRSHARRRRPPPP 1406
Query: 1360 PGAAGAQALEKLEAAESLVLEQSFLHGITLLSEIAELEL--ERRSQEMGGAE 1409
P +A E E + + + +++ L L ER Q+ GA+
Sbjct: 1407 PPPPPPRAYEPRSEFEQMTILYDIWNSGLDSEDMSYLRLTYERLLQQTSGAD 1458
Score = 35.4 bits (80), Expect = 0.85
Identities = 64/310 (20%), Positives = 100/310 (32%), Gaps = 44/310 (14%)
Query: 71 VASGMGPSASSHGSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYL-- 128
+A+ +ASS S L S S S + S+ Q ++ A+ YP+Y
Sbjct: 327 IAATTAATASSSASSSSLSSSSSSSSSSSSS----QFRSSDAN----------YPAYYES 372
Query: 129 ---HLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHAPSART 185
+ H P + G P +T + P + P P P++
Sbjct: 373 WNRYQRHTSYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEA 432
Query: 186 P--------GGGHSSGAPAKGSSSRDGPAKERAGRGGEPPP-LFGKKDPRARGEEASGPR 236
P GGG G + R P R G P P + P A + +S
Sbjct: 433 PPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFA--QHSSLDS 490
Query: 237 GVVDLTQEARA---------EGRQDRGPPRLAERLSPFLAESKTKNAALQP-----SVLT 282
+ L +E R+ E ++ L R + S + + P +
Sbjct: 491 RIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFED 550
Query: 283 MCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPP 342
+ G+G+ G +A + + P P P P PPPP PP
Sbjct: 551 VAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPP 610
Query: 343 KGPPAPPAAT 352
PP P A+
Sbjct: 611 PPPPPPYLAS 620
Score = 35.4 bits (80), Expect = 0.85
Identities = 33/110 (30%), Positives = 39/110 (35%), Gaps = 15/110 (13%)
Query: 945 EMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVA-- 1002
E EE+ S L A +G G P PP A P + R SP A
Sbjct: 511 EEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANG 570
Query: 1003 ALKAKVIQKLEDV---------SKPPAYAYPATPSSHPTSPPPASPPPTP 1043
+A +D+ S PPA TP P PPP PPP P
Sbjct: 571 QNQASPCSSGDDMEISDDDRGGSPPPA----PTPPQQPPPPPPPPPPPPP 616
Score = 34.7 bits (78), Expect = 1.4
Identities = 60/243 (24%), Positives = 77/243 (31%), Gaps = 41/243 (16%)
Query: 2344 RAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAF 2403
R AT EE +T PS T P P D+ + P + PP+P P P
Sbjct: 385 RRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEP-PEPGGG 443
Query: 2404 TSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELL-- 2461
P P E R P+ A A SG+ P E
Sbjct: 444 GGGGGPSPERE-----------------EVRTSPRPASPA-RSGSPAPETTNESVPFAQH 485
Query: 2462 VKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKAT 2521
LD K +++K + L + +E S + LG+ GS P +
Sbjct: 486 SSLDSRIEMLLKEQRSKFSFLASDTEE----EEENSSMVLGARD--TGSEVPSG----SG 535
Query: 2522 DGDLAQEPGPGLTFED-----SGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSS 2576
G P P FED SG P A E A +S SSG S
Sbjct: 536 HGPCTPPPAPA-NFEDVAPTGSGEP----GATRESPKANGQNQASPCSSGDDMEISDDDR 590
Query: 2577 SGS 2579
GS
Sbjct: 591 GGS 593
Score = 33.5 bits (75), Expect = 3.2
Identities = 17/34 (50%), Positives = 19/34 (55%), Gaps = 5/34 (14%)
Query: 327 GPRPCPSPLPP--PPAPPKGPPAPP---AATPAG 355
G P P+P PP PP PP PP PP A+ P G
Sbjct: 591 GGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLG 624
Score = 33.5 bits (75), Expect = 3.2
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 19/145 (13%)
Query: 2265 DDGDTGRIPLSHIRLLPPDYK--IQCAEPSPALL----VPSAKRRSRKTSKDTGEGKDGG 2318
D+ + R LSHI LL +Y ++ P+PAL VP+ + + E +
Sbjct: 1284 DEAERPRPLLSHI-LLEHNYALAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVV 1342
Query: 2319 TAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPE 2378
A +EEP + + R+ + +G+ EEG +E S SS+ +
Sbjct: 1343 VAEAEEPKPQQLQQQRE-EGEEEGE-----EEGEEEEEESSD------SSSSSDGEGALR 1390
Query: 2379 PVDKRAKAPKARPAPPQPSPAPPAF 2403
R+ A + RP PP P P P A+
Sbjct: 1391 RRSLRSHARRRRPPPPPPPPPPRAY 1415
Score = 32.7 bits (73), Expect = 5.5
Identities = 22/64 (34%), Positives = 24/64 (37%), Gaps = 3/64 (4%)
Query: 982 PAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPP 1041
PA T + PPP P P L + L PAY P P P P PPP
Sbjct: 596 PAPTPPQQPPPPPPPPPPPPPYLASL---PLGYPPHQPAYLLPPRPDGPPPPEYPPPPPP 652
Query: 1042 TPGI 1045
P I
Sbjct: 653 PPHI 656
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 89.4 bits (220), Expect = 5e-17
Identities = 244/1129 (21%), Positives = 371/1129 (32%), Gaps = 248/1129 (21%)
Query: 1711 ARGQPKSAHSPF----ASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVA 1766
A+G P +P A V+S + EED E +E S + TP+ + A
Sbjct: 307 AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE----SSDSEEETPAAKALLQA 362
Query: 1767 KNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDES 1826
K A G +AP P+ + P A+A++ + +S S
Sbjct: 363 K----ASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS-----S 413
Query: 1827 SEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLS 1886
SEE D EEE + + SG ++ RA S +ES R A+ P GP+ +
Sbjct: 414 SEESDSEEEAPAQAKPSGKAPQV----RAASAPAKES-----PRKGAAPAPPRKTGPAAA 464
Query: 1887 VVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAP 1946
VQ+ +++ + +S E + ++VK +SP G+G
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG--------- 515
Query: 1947 TPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHD 2006
P +G P P K GP P + G D + + S+
Sbjct: 516 -PLGKGAGPVPPGKV--------------GPATPSAQVGKWEEDSESSSEESSDSSDGEV 560
Query: 2007 ASAAAPAPVST----APATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGL 2062
+A APA + A TS AKG P A + K K + +E+ A
Sbjct: 561 PTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA-- 618
Query: 2063 PPPRAPALPSEARAPHASSLTAAK------RSKAKAKGKEVK---KENRGKGGAVSKLME 2113
APA + A+A A + K + A AK V+ + R G A S
Sbjct: 619 DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGS 678
Query: 2114 SMA-AEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAPRSCIIDKDELKDGLRVLIPMDDK 2172
S A A P +DSS SE+ D +E K GL V +
Sbjct: 679 SPAVAGGTQRPAEDSSSSEES---------------------DSEEEKTGLAVTVGQAKS 717
Query: 2173 LLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAA 2232
+ V+ P V+G G + V P T P T++ A
Sbjct: 718 VGKGLQVKAASVP------VKGSLG-------------QGTAPVLPGKTG--PTVTQVKA 756
Query: 2233 YWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPS 2292
+ ++D + E D + P ++ K Q
Sbjct: 757 -------------------EKQEDSESSEEESDSEEAAASP---AQVKTSVKKTQAKANP 794
Query: 2293 PALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPG----AKARGRGRKPSAKAKGDRAATL 2348
A PSAK GT + PG A A+ + R PS R
Sbjct: 795 AAARAPSAK----------------GTISA--PGKVVTAAAQAKQRSPSKVKPPVR---- 832
Query: 2349 EEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPA 2408
NP + ST LA P+S P K+ + + + + S + +
Sbjct: 833 ---NPQN---STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
Query: 2409 PEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEG 2468
+P + +LAPA + P+K A G GP A K D G
Sbjct: 887 VKPSGKTHQIRAALAPA--------KESPRKGAAPTPPGKTGP-----SAAQAGKQDDSG 933
Query: 2469 VTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQE 2528
+S +S EA PAA +S P
Sbjct: 934 SSSEESDSDGEA-------------------------PAAVTSAQVIKPPLIFVDPNRSP 968
Query: 2529 PGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSS-------------------------- 2562
GP T + +P KA+A + A S S S
Sbjct: 969 AGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAH 1028
Query: 2563 -----SSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSS 2617
+S + +SSS SS S+ + +E D GT ++S A +
Sbjct: 1029 PRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
Query: 2618 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDS 2677
++ + SS S SS SSS S + S+ + + S + T E++
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEET 1148
Query: 2678 SCSSDDEAAPAPTAGPSAQAALP--TKATKQAGKARPSAHS--------PGKKTPAPQPQ 2727
+ S ++ AP+ + P T A QA KA P S K P + +
Sbjct: 1149 AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1208
Query: 2728 APPPQPTQPLQPKA---QAGAKSRPKK----REGVHLPTTKELAKRQRL 2769
A P Q L PK +A + + P+K ++G P LA + +
Sbjct: 1209 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNI 1257
Score = 73.2 bits (178), Expect = 4e-12
Identities = 111/497 (22%), Positives = 175/497 (35%), Gaps = 72/497 (14%)
Query: 2298 PSAKRRSRKTSKDTGEGKDG---GTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPT 2354
P+ + S ++K++ K G G P K AK + + + EEG+ +
Sbjct: 220 PAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSES 279
Query: 2355 DEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKAR--------PAPPQPSPAPPAFTSC 2406
+E P+ T K+ + + RA + A+ PAPP + A + T
Sbjct: 280 EEEA-------PAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA 332
Query: 2407 PAPEPFAELPAPATS-----LAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELL 2461
PE +E + +S A + K + AA + PR+ A
Sbjct: 333 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP-- 390
Query: 2462 VKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKAT 2521
G T P KA+ RE+ +E S PA KAP +A
Sbjct: 391 -----PGKTGPAVAKAQAGK--REEDSQSSSEESDS----EEEAPAQAKPSGKAPQVRAA 439
Query: 2522 DGDLAQEPGPGLTFEDSGNPKSPDKAQAE-QDGAEESESSSSSSSGSSSSSSSSSSSGSE 2580
+ P G P+ A A+ Q G +E +S SSS S + ++ + ++
Sbjct: 440 SAPAKESPRKGAA---PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496
Query: 2581 TE--GEEEGDKNGDG-GCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSS 2637
+ G+ K G G G+ PA+ S+ S SSS SS SS
Sbjct: 497 VKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS 556
Query: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------------SSSTTDEDSSC 2679
++ + + S + + +SS + +S + E+SS
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 616
Query: 2680 SSDDEAAPAPTAGPSAQAALPTKATKQAGK-------ARPSAHSPGKKTPAPQPQAPPPQ 2732
S+D E APA A+ AL TK K A+ + G + P A P
Sbjct: 617 SADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA 676
Query: 2733 PTQPLQPKAQAGAKSRP 2749
+ P A AG RP
Sbjct: 677 GSSP----AVAGGTQRP 689
Score = 67.8 bits (164), Expect = 2e-10
Identities = 258/1243 (20%), Positives = 416/1243 (33%), Gaps = 179/1243 (14%)
Query: 935 ERLKAQEHRAEMEEKGSKRGLEA-AGKAGLATAGPGLLPRKPPGLAAGPA-GTYGKAVSP 992
+R K E +E E+GS+ EA AG A +L + A+ PA GT GK +P
Sbjct: 261 KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRA---ASAPAKGTPGKGATP 317
Query: 993 PPSPRASPVAALKAKVIQKLEDVSK------------PPAYAYPATPSSHPTSPPPASPP 1040
P +A VA+ + K + ED P A A +S TS A+
Sbjct: 318 APPGKAGAVAS-QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASA 376
Query: 1041 PTPGITRKEEAPE-----NVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPY 1095
P RK AP K ++E S + SD P QA P
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436
Query: 1096 PFLLQPTAAADADGLAPDVPL---PADGPERLALSPEDKPIRLSPSKITEPLREGPEEEP 1152
P + G AP P PA ++ ED S S E + E
Sbjct: 437 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED-----SRSSSEE---SDSDREA 488
Query: 1153 LAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQS 1212
LA A+V+ + + P P S + + A P P G G AQ S
Sbjct: 489 LAAMNA-AQVKPLGKSPQVKPA--STMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDS 545
Query: 1213 CAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEEPVEV-PVAVPVV 1271
+ E D +G P +P + + L +P AK P + PVAV V
Sbjct: 546 ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP-----AKGPPQKAGPVAVQVK 600
Query: 1272 EAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQF 1331
P + S E + + A + + P+L+ + T A
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAK-PALKIPQTKACPKKTNTTASAKVAPV 659
Query: 1332 LPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLEQSFLHGITLLS 1391
+ P A + A P G A + + ES E+ +T+
Sbjct: 660 RVGTQAPRKAGTATSPAGSSPAVA-----GGTQRPAEDSSSSEESDSEEEKTGLAVTV-- 712
Query: 1392 EIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDPLKNLRLPRELK 1451
+++ +G + A ++ L G+ + GP V +K
Sbjct: 713 --------GQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK--------- 755
Query: 1452 PNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDS- 1510
E+ +SS E+ D+ E A+V+ K+ Q + R S
Sbjct: 756 -----------AEKQEDSESSEEESDSEEA--AASPAQVKTSVKKTQAKANPAAARAPSA 802
Query: 1511 EDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKS------GHSSGKLSSKSLLTSD 1564
+ P + + + R +PS + PP + ++ G +S K++ T+
Sbjct: 803 KGTISAPGKVVTAAAQAKQR----SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
Query: 1565 DYELG----AGIRKRHKGSEEEHDAL---------------IGMGKARGRNQTWDEHEAS 1605
+ G +G + SEEE + L + K R
Sbjct: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGK 918
Query: 1606 SDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSD---SAGGKSKTSGGC 1662
+ + K+ S E+ S + ++T +K P F D S G + T
Sbjct: 919 TGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQA 978
Query: 1663 GRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSPF 1722
TP RKA A SS T+ + G + P
Sbjct: 979 QAASTP--------RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPR 1030
Query: 1723 ASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGL 1782
+ +S + + S+E + D +GP++ + A + A P+ T
Sbjct: 1031 IAPKASMAGASSSKESSR-ISDGKKQEGPATQVDS--------AVGTLPATSPQST---- 1077
Query: 1783 AAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEA 1842
+++ K ++P +++A SD SE+S D SEE+ E +
Sbjct: 1078 ----SVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQ------G 1127
Query: 1843 SGGGYRLGARERALSPGLEESGL-----GLLARFAASALPSPTVGPSLSVVQLEAKQKAR 1897
+ + LG +EE+ ++A + +L S + P L+ +A +
Sbjct: 1128 AKSAHTLGPTPSRTETLVEETAAESSEDDVVA--PSQSLLSGYMTPGLTPANSQASKATP 1185
Query: 1898 KKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSS 1957
K + S+ T D + + + + + AG+L PK G G+ S P + +
Sbjct: 1186 KLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTG-GKEAASGTTPQKSRKPKKGAG 1244
Query: 1958 PDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTR-RRSERIFLHDASAAAPAPVS 2016
+A + + L G P EA +AS + T ER + D
Sbjct: 1245 NPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVD---------- 1294
Query: 2017 TAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARA 2076
T KG RK +G + PR KKK K+ G G G EA
Sbjct: 1295 ----TTKESSRKGWESRKRKLSGDQPAARTPRSKKK-KKLGAGEG----------GEASV 1339
Query: 2077 PHASSLTAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEE 2119
+ T +K + K KE +GKG S+ + EE
Sbjct: 1340 SPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEE 1382
Score = 66.2 bits (160), Expect = 4e-10
Identities = 328/1617 (20%), Positives = 533/1617 (32%), Gaps = 323/1617 (19%)
Query: 1129 EDKPIRLSPSKITEPLR--EGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAE- 1185
ED ++ +++++P+ E EEE AE E + T L + LP E
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRL--ASTNSSVLGADLPSSMKEK 124
Query: 1186 AMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDL 1245
A A AG G + ATG++ A + + G PR + EP
Sbjct: 125 AKAETEKAGKTGNSMPHP----ATGKTVA------NLLSGKSPRKSA----EPSANT--- 167
Query: 1246 GVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQC 1305
TLV EE +VP A + G+ ++S S D EG+
Sbjct: 168 -------TLVSETEEEG----SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGK- 215
Query: 1306 PSLEP---------------QEAVPVLGSTCFL--------------------EEASSDQ 1330
PS++P ++A P G + E SS++
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 1331 FLPSLEDPLAGMNALAAAAEL---PQARPLPSPGAAGAQALEKLEAAESLVLEQSFLHGI 1387
S E+ AG + A+E +A P+ G G A V Q+
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT----- 330
Query: 1388 TLLSEIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDPLKNLRLP 1447
+ E + E S+E +E A +L A+G P + + P
Sbjct: 331 --KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 388
Query: 1448 RELKPNKKYSWMRKKE--ERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQRELVKLQ 1505
P K + K + +R +SS E+ D+ E E Q K + Q
Sbjct: 389 AP--PGKTGPAVAKAQAGKREEDSQSSSEESDSEE--------EAPAQAKPSGKAP---Q 435
Query: 1506 RRRDSEDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLSS-KSLLTSD 1564
R S +E P + A P PRK A + + ++ S SS + S + L +
Sbjct: 436 VRAASAPAKESPRKGAA---PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAM 492
Query: 1565 DYELGAGIRKRHKGSEEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQE 1624
+ A ++ K + + + +GMG G+ + K A+
Sbjct: 493 N---AAQVKPLGKSPQVKPASTMGMGPL-GKGA------------GPVPPGKVGPATPSA 536
Query: 1625 QLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGL 1684
Q+ ++D S + SDS+ G+ T+ + P A K L
Sbjct: 537 QVGK--------WEEDSESSSEESSDSSDGEVPTA------VAP----------AQEKSL 572
Query: 1685 GLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKD 1744
G L++ + + V + + + +S + E S DS + EE
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS------DSADSEEAPAA 626
Query: 1745 EWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLL 1804
AQ + K+ + C N+ A+ + G APR K ATS
Sbjct: 627 MTAAQAKPALKIPQTKACPKKT-NTTASAKVAPVRVGTQAPR--KAGTATS--------- 674
Query: 1805 REAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESG 1864
A + + + ++ + SSEE D EEE +G +G + +++ GL+
Sbjct: 675 -PAGSSPAVAGGTQRPAEDSSSSEESDSEEE------KTGLAVTVG-QAKSVGKGLQVKA 726
Query: 1865 L-----GLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEV 1919
G L + A LP T GP+++ V KA K+E+ +S ++ ES+
Sbjct: 727 ASVPVKGSLGQGTAPVLPGKT-GPTVTQV------KAEKQEDSES--------SEEESDS 771
Query: 1920 KVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVE--KGRKARKLRGP 1977
+ SPA + K AA P A+G S+P K A K R K++ P
Sbjct: 772 EEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI-SAPGKVVTAAAQAKQRSPSKVKPP 830
Query: 1978 KEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKD 2037
P+ S + A P S K A P +D
Sbjct: 831 VR-----NPQNS------------------TVLARGPASVPSVGKAVATAAQAQTGPEED 867
Query: 2038 AGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEV 2097
+G +++ D ++ + A PS ++L AK S K
Sbjct: 868 SGSSEEESDSEEEAE------------TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915
Query: 2098 KKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAPRSCIIDKD 2157
GK G + + A ++D + D P AV P +D +
Sbjct: 916 P----GKTGPSA----AQAGKQDDSGSSSEESDSDGEAP--AAVTSAQVIKPPLIFVDPN 965
Query: 2158 ELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNR---------PHIYCLEQL 2208
G Q +P R R + P CL
Sbjct: 966 RSPAGPAAT---------PAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPG 1016
Query: 2209 LQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGD 2268
++ ++ + A R P+ + A S++ + G + +G V D
Sbjct: 1017 IRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGK--------KQEGPATQV---DSA 1065
Query: 2269 TGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKT----SKDTGEGKDGGTAGSEE 2324
G +P + P +Q A+ + L P + T S D E ++GSEE
Sbjct: 1066 VGTLPATS----PQSTSVQ-AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEE 1120
Query: 2325 PGAKARGRGRKPSAKAKGDRAATLEEGNPTDE------VPSTPL-------ALEPSSTPG 2371
G +G + R TL E + PS L L P+++
Sbjct: 1121 DGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQA 1180
Query: 2372 SKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMP 2431
SK +P +D A P A P+ A + +P T A T P
Sbjct: 1181 SKATPK--LDSSPSVSSTLAAKDDPDGKQEA-----KPQQAAGMLSPKTGGKEAASGTTP 1233
Query: 2432 ATRPKPKKARAAEESGAK-----------GPRRPGEEAELLVKLDHEGVTSPKSKKAKEA 2480
KPKK ++ G P EA++ + + +T ++ K+
Sbjct: 1234 QKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV-KVLTELLEQERKKV 1292
Query: 2481 LLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGN 2540
+ ++ GW+ K LS G P A + P K A E G + +
Sbjct: 1293 VDTTKESSRKGWESRKRKLS-GDQPAA------RTPRSKKKKKLGAGEGGEASVSPEKTS 1345
Query: 2541 PKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT-GG 2599
S KA+ ++ + E S GS G++ E EEE K G GT G
Sbjct: 1346 TTSKGKAKRDKASGDVKEKKGKGSLGSQ---------GAKDEPEEELQK----GMGTVEG 1392
Query: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ S S+ S + +S+ S S S ++ +
Sbjct: 1393 GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1449
Score = 65.1 bits (157), Expect = 1e-09
Identities = 94/379 (24%), Positives = 148/379 (39%), Gaps = 40/379 (10%)
Query: 2432 ATRPKPKKARAAEESGAKG-PRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAG 2490
+T ++ AE AK PR + +L G P S K K A E G
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVL------GADLPSSMKEK-AKAETEKAGKT 135
Query: 2491 GWQEP-----KSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPD 2545
G P K++ +L S S+EP A ++ +E G F + P
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE---TEEEGSVPAFGAAAKPGMVS 192
Query: 2546 KAQAEQDGAEESESSSSSS-----SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600
QA+ + S SS + S + +SS S E+ + G G T
Sbjct: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
Query: 2601 NCSAA--SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS-------SSSSSSSSSSS 2651
A + RA P S SS S S + + + S +S ++S+ + +
Sbjct: 253 KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312
Query: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKA---TKQAG 2708
++ + + + +S + + E+ S SS +E++ + P+A+A L KA T Q G
Sbjct: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG 372
Query: 2709 KAR-PSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQ 2767
A P+ SP +K AP PP T P KAQAG + + + +E A Q
Sbjct: 373 AASAPAKESP-RKGAAP----APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE-APAQ 426
Query: 2768 RLPSVENRPKIAAFLPARQ 2786
PS + AA PA++
Sbjct: 427 AKPSGKAPQVRAASAPAKE 445
Score = 61.2 bits (147), Expect = 1e-08
Identities = 108/480 (22%), Positives = 182/480 (37%), Gaps = 67/480 (13%)
Query: 1706 EVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMV 1765
E+G K + + +A + VS ++S E+EE + E P + S+L + +
Sbjct: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADL 117
Query: 1766 AKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLR------EAEARSSFSDSSEE 1819
+ K + K G P PAT + L + E A ++ +EE
Sbjct: 118 PSSMKEKAKAETEKAGKTG--NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
Query: 1820 ----------------SFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEES 1863
S Q +SS E+ +E + G A+ +A S +ES
Sbjct: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSS--SDETDVEGKPSVKPAQVKASSVSTKES 233
Query: 1864 GLGLLARFAASALPSP----TVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEV 1919
A A P+P V P + L ++A+K EE +E SESE
Sbjct: 234 P-------ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEE-----SESSEEGSESEE 281
Query: 1920 KVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKE 1979
+ + + + +K L S A +G P+ P KA AV KA K P+E
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG-AVASQTKAGK---PEE 337
Query: 1980 PGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSR-------CAKGGPL 2032
+ E+SD + T + + + ++APA ++ R K GP
Sbjct: 338 DSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPA 397
Query: 2033 SPRKDAG-RAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAK 2091
+ AG R +D + ++ +E P P +AP + RA A + + ++ A
Sbjct: 398 VAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP----QVRAASAPAKESPRKGAAP 453
Query: 2092 AKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVE-RPLTPAPR 2150
A + K G + ++ EED + + S S+ E L A + +PL +P+
Sbjct: 454 APPR--------KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 505
Score = 60.5 bits (145), Expect = 2e-08
Identities = 101/474 (21%), Positives = 167/474 (35%), Gaps = 63/474 (13%)
Query: 2354 TDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFA 2413
T E+ A E ++ K +P+ + + A + + A P S + A
Sbjct: 56 TSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGA 115
Query: 2414 ELPAPATSLAPAPLITMPAT---RPKPKKARA-AEESGAKGPRR---PGEEAELLVKLDH 2466
+LP+ A A T P P + A K PR+ P L+ + +
Sbjct: 116 DLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
Query: 2467 EG-------VTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPA----AGSSEPKA 2515
EG P A +A ED + + + S PA + S ++
Sbjct: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSS--DETDVEGKPSVKPAQVKASSVSTKES 233
Query: 2516 PWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSS 2575
P KA P PG + + K A++ E ES SS GS S + +
Sbjct: 234 PARKAA-------PAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE-GSESEEEAPA 285
Query: 2576 SSGSETEGEEE--------GDKNGDGGCGT-----GGRNCSAASSRAASPASSSSSSSSS 2622
+ S+ + E+ G G G G A+ ++A P S SSS
Sbjct: 286 GTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE 345
Query: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----------SSSSST 2672
SS S + ++ + + +S +S ++S+ + S ++ + + +
Sbjct: 346 SSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK 405
Query: 2673 TDEDSSCSSD--DEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPP 2730
+EDS SS+ D AP AQA KA + + P+ SP +K AP P
Sbjct: 406 REEDSQSSSEESDSEEEAP-----AQAKPSGKAPQVRAASAPAKESP-RKGAAP----AP 455
Query: 2731 PQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPA 2784
P+ T P + Q G + + + +E V+ K PA
Sbjct: 456 PRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 509
Score = 58.5 bits (140), Expect = 9e-08
Identities = 120/569 (21%), Positives = 189/569 (33%), Gaps = 71/569 (12%)
Query: 181 PSARTPGGGHSSGAPAKGSSSRDGPAKERAG------RGGEPPPLFGKKDPRARGEEASG 234
PS + SS + + + + PA + G +GG PP K P EE+
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPE---EESES 272
Query: 235 PRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDV--- 291
+ +EA A R + +E++ A S G AG V
Sbjct: 273 SEEGSESEEEAPAGTRSQ---VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 329
Query: 292 ---GLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGP-PA 347
G P +E+ + ++ + A+ L + + + + P +P KG PA
Sbjct: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 389
Query: 348 PPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRP 407
PP T V + E + S E + P A Q R A A +E+ R
Sbjct: 390 PPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK 449
Query: 408 GVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLK 467
G APP P + ++ RS +D + A A+ K L K
Sbjct: 450 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ-------VKPLGK 502
Query: 468 PEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLA 527
+P GP G A + PG+ P P ++G + +
Sbjct: 503 -SPQVKPASTMGMGPLGKGAGP------VPPGKVGPATPSA-----QVGKWEEDSESSSE 550
Query: 528 AQHHHSRAEEEAAVVAASSSK-------KAYLDPGAVLPRSAATCG------RPVADMHS 574
S E AV A K P P+ A +P+ + S
Sbjct: 551 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES 610
Query: 575 AAHGSGEASAMQSLIKYSGSFARDAVAV-RPGGCGKKSPFGGLGTMKPEPAPTSAGASRA 633
+ S A + ++ + + A+ A+ + + C KK+ + P T A
Sbjct: 611 SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAG 670
Query: 634 QARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKD 693
A P PA GG Q RP E S + E++ G+AV V + K
Sbjct: 671 TATSPAGSSPAVAGGTQ------RP-------AEDSSSSEESDSEEEKTGLAVTVGQAKS 717
Query: 694 SGGSGRLGPGLVDQERSLSLSNVKGHGRA 722
+G GL + S+ + G G A
Sbjct: 718 ------VGKGLQVKAASVPVKGSLGQGTA 740
Score = 57.8 bits (138), Expect = 2e-07
Identities = 114/534 (21%), Positives = 182/534 (34%), Gaps = 84/534 (15%)
Query: 2291 PSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSE---EPGAKARGRGRKPSAKAKGDRAAT 2347
P PA A S K+ + + E T SE E A G KP + G ++
Sbjct: 140 PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSS 199
Query: 2348 LEE-GNPTDEV-----PSTPLALEPSSTPGSKKSP-----PEP-----VDKRAKAPKARP 2391
E+ + +DE PS A +S+ +K+SP P P V + K P
Sbjct: 200 SEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP 259
Query: 2392 APPQPSPAPPAFTSCPAPEPFAELPAPATS------------LAPAPLITMP---ATRPK 2436
A P + +S E E PA S A AP P AT
Sbjct: 260 AKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAP 319
Query: 2437 PKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPK 2496
P KA A G +P E++E E S + A +ALL + G
Sbjct: 320 PGKAGAVASQTKAG--KPEEDSE---SSSEESSDSEEETPAAKALLQAKASGK------T 368
Query: 2497 SLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEE 2556
S + S P + AP P + GP + +G + ++ +E+ +EE
Sbjct: 369 SQVGAASAPAKESPRKGAAPAPPG-------KTGPAVAKAQAGKREEDSQSSSEESDSEE 421
Query: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616
+ + SG + ++S+ E+ + G R A+++
Sbjct: 422 EAPAQAKPSGKAPQVRAASAPAKESPRK--------GAAPAPPRKTGPAAAQVQVGKQEE 473
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------------SS 2658
S SSS S S + ++ +++ S +S+ ++
Sbjct: 474 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
Query: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDE--AAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
S+ S ++ E+SS SSD E A AP S L K T K P
Sbjct: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG 593
Query: 2717 P---GKKTPAPQPQAPPPQPTQPLQPKAQA-GAKSRPKKREGVHLPTTKELAKR 2766
P K P + + + +A A + + + + +P TK K+
Sbjct: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
Score = 51.2 bits (121), Expect = 1e-05
Identities = 87/363 (23%), Positives = 129/363 (35%), Gaps = 57/363 (15%)
Query: 944 AEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAA 1003
+E EE+GS AA K G+ +AG + ++ GK P +AS V+
Sbjct: 171 SETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVST 230
Query: 1004 LKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLEL 1063
++ + P TP + PPA P EE E+ E + E
Sbjct: 231 KESPA----RKAAPAPGKVGDVTPQVKGGALPPAKRAKKP-----EEESESSEEGSESEE 281
Query: 1064 EKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPER 1123
E A + Q S+ L A+A A G PA +
Sbjct: 282 EAPAGTRSQVKASE------------------KILQVRAASAPAKGTPGKGATPAPPGKA 323
Query: 1124 LALSPE---DKPIRLSPSKITEPLREGPEEEPLAER--EVKAEVEDMDEGPTELPPLESP 1178
A++ + KP S S +E + EE P A+ + KA + G P ESP
Sbjct: 324 GAVASQTKAGKPEEDSESS-SEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESP 382
Query: 1179 LPLPAAEAMATPSPAGGCGGGLLEAQA--LSATGQSCAEPSECPDFVEGPEPRVDSPGRT 1236
A P+P G G + +AQA QS +E S+ + ++P +
Sbjct: 383 ------RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE---------EAPAQA 427
Query: 1237 EPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSE--SQPTLEMS 1294
+P A + P AKE P + P + P QV E S+ + E S
Sbjct: 428 KPSGKAPQVRAASAP-----AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 482
Query: 1295 DCD 1297
D D
Sbjct: 483 DSD 485
Score = 49.3 bits (116), Expect = 6e-05
Identities = 250/1286 (19%), Positives = 428/1286 (33%), Gaps = 227/1286 (17%)
Query: 917 QQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPP 976
+ A QA + + S + +E AE E + L + + L P + K
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 977 GLAAGPAGTYGKAVSPPP------------SPRASPVAALKAKVIQKLEDVSKPPAYAYP 1024
AG G ++ P SPR S + ++ + E+ PA+
Sbjct: 127 A-ETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
Query: 1025 ATPSSHPTSPPPASPPPTPGIT-----------RKEEAPENVVEKKDLELEKEAPSPFQA 1073
A P +S T + + + + V K+ K AP+P +
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
Query: 1074 LFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPE---- 1129
D+ P+ ALPP P + + + +G + PA ++ S +
Sbjct: 246 --GDVTPQVKGGALPPAKRAKKP---EEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 1130 ---DKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEA 1186
P + +P K P G ++ + ED + E +S PAA+A
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE--SSDSEEETPAAKA 358
Query: 1187 MATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLG 1246
+ +G S G + A E P P P PG+T P A G
Sbjct: 359 LLQAKASG----------KTSQVGAASAPAKESPRKGAAPAP----PGKTGPAVAKAQAG 404
Query: 1247 VQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGE---- 1302
+ ++ ++E E EE AQ PS P ++ PA E
Sbjct: 405 -KREEDSQSSSEESDSE------------EEAPAQAKPSGKAP--QVRAASAPAKESPRK 449
Query: 1303 GQCPSLEPQEAVPVLGSTCF----LEEASSDQFLPSLEDPLAGMNA--LAAAAELPQARP 1356
G P+ P++ P + SS + S + LA MNA + + PQ +P
Sbjct: 450 GAAPA-PPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
Query: 1357 LPSPG----AAGAQALEKLEAAESLVLEQSFLHGITLLSEIAELELERRSQEMGGAERAL 1412
+ G GA + + + Q + E +E E S G
Sbjct: 509 ASTMGMGPLGKGAGPVPPGKVGPATPSAQ-----VGKWEEDSESSSEESSDSSDGEVPTA 563
Query: 1413 VARPSLESLLAAGSHMLREVLDGPVVDPLKNLRLPRELKPNKKYSWMRKKEERMYAMKSS 1472
VA +SL G+ + + P P P++ P K + + + S
Sbjct: 564 VAPAQEKSL---GNILQAKPTSSPAKGP------PQKAGPVAVQVKAEKPMDNSESSEES 614
Query: 1473 LEDMDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDSEDRREEPHRSLARRGPGRPRKR 1532
+ D+ E M A+ + K Q + ++ + + P R G PRK
Sbjct: 615 SDSADSEEAPAAMTAAQAKPALKIPQTKACP-KKTNTTASAKVAP----VRVGTQAPRKA 669
Query: 1533 THA--PSALSP--------PRKRGKSGHSSGKLSSK---SLLTSDDYELGAGIRKRH--- 1576
A P+ SP P + S S K ++ +G G++ +
Sbjct: 670 GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASV 729
Query: 1577 --KGSEEEHDALIGMGKARGRNQTWDEHEASSDF-ISQLKIKKKKMASDQEQLASKLDKA 1633
KGS + A + GK G T + E D S+ + ++ A+ Q+ + + K
Sbjct: 730 PVKGSLGQGTAPVLPGKT-GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
Query: 1634 LSLTKQDKLKSP-FKFSDSAGGKSKTSGGCGRYLTPY----DSLLGKNRKALAKG----- 1683
+ ++P K + SA GK T+ + +P +N LA+G
Sbjct: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
Query: 1684 -LGLSLKSSREGKH-------------------------KRAAKTRKMEVGF-KARGQPK 1716
+G ++ ++ + + K + KT ++ A+ P+
Sbjct: 849 SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPR 908
Query: 1717 SAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPK 1776
+P + S ++D+ E + S + ++ + V K P
Sbjct: 909 KGAAPTPPGKTGPSAAQAGKQDDSGSSSE---ESDSDGEAPAAVTSAQVIKPPLIFVDPN 965
Query: 1777 LTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEEL 1836
+ G AA P A + P E+ ARSS S+S +E +
Sbjct: 966 RSPAGPAA----TPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 1021
Query: 1837 --------EEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVV 1888
+AS G +S G ++ G A LP+ P + V
Sbjct: 1022 VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPA--TSPQSTSV 1079
Query: 1889 QLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTP 1948
Q + K RK + + T+ + +SE S + + G G G A +
Sbjct: 1080 QAKGTNKLRKPKLPEVQQATKAPESSDDSE----DSSDSSSGSEEDGEGPQG----AKSA 1131
Query: 1949 GARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRS-------ER 2001
GP PS + + VE E E+S+DD+ +S
Sbjct: 1132 HTLGPTPS---RTETLVE----------------ETAAESSEDDVVAPSQSLLSGYMTPG 1172
Query: 2002 IFLHDASAAAPAP-VSTAPATKTSRCAKGGP--------------LSPRKDAGRAKDRKD 2046
+ ++ A+ P + ++P+ ++ AK P LSP+ A
Sbjct: 1173 LTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTT 1232
Query: 2047 PRKKKKGKEAGPGAGLPPPRAPALPS 2072
P+K +K K+ GAG P AL S
Sbjct: 1233 PQKSRKPKK---GAGNPQASTLALQS 1255
Score = 46.2 bits (108), Expect = 5e-04
Identities = 107/495 (21%), Positives = 162/495 (32%), Gaps = 79/495 (15%)
Query: 170 AGAPGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFG---KKDPR 226
AG G+ H + +T S +P K + P FG K
Sbjct: 132 AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 227 ARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPS----VLT 282
+ G+ S + E EG+ P ++ + S ES + AA P V
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEGKPSVKPAQV-KASSVSTKESPARKAAPAPGKVGDVTP 250
Query: 283 MCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTET------LLPGPRPCPSPLP 336
GGA A E ++E + +E A R++ L P+
Sbjct: 251 QVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGT 310
Query: 337 P----PPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIAS 392
P PAPP A + T AG E E + P+ +A + + S
Sbjct: 311 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGK-TS 369
Query: 393 QARDARAREREAGRPGVLQAPPGSPRPL--DRPEGLREKNSVIRSLKRPPPADAPTVRAT 450
Q A A +E+ R G APPG P G RE++S S + +AP
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP----- 424
Query: 451 RASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKW 510
A +P +AP+ A A + + G P P TGP
Sbjct: 425 -------------------AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGP---- 461
Query: 511 KPFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVA 570
AA Q+ V Q SR+ E + + A ++ V P + +P +
Sbjct: 462 --------AAAQVQV-GKQEEDSRSSSEES--DSDREALAAMNAAQVKPLGKSPQVKPAS 510
Query: 571 DMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAPTSAGA 630
M G G A V PG G +P +G + + +S +
Sbjct: 511 TMGMGPLGKG------------------AGPVPPGKVGPATPSAQVGKWEEDSESSSEES 552
Query: 631 S-RAQARLPHSGGPA 644
S + +P + PA
Sbjct: 553 SDSSDGEVPTAVAPA 567
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 87.8 bits (216), Expect = 1e-16
Identities = 241/1130 (21%), Positives = 365/1130 (32%), Gaps = 249/1130 (22%)
Query: 1711 ARGQPKSAHSPF----ASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVA 1766
A+G P +P A V+S + EED E +E S + TP+ + A
Sbjct: 307 AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE----SSDSEEETPAAKALLQA 362
Query: 1767 KNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDES 1826
K A G +AP P+ + P A+A++ + +S S
Sbjct: 363 K----ASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS-----S 413
Query: 1827 SEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLS 1886
SEE D EEE + + SG ++ RA S +ES R A+ P GP+ +
Sbjct: 414 SEESDSEEEAPAQAKPSGKAPQV----RAASAPAKES-----PRKGAAPAPPRKTGPAAA 464
Query: 1887 VVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAP 1946
VQ+ +++ + +S E + ++VK +SP G+G
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG--------- 515
Query: 1947 TPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHD 2006
P +G P P K GP P + G D + + S+
Sbjct: 516 -PLGKGAGPVPPGKV--------------GPATPSAQVGKWEEDSESSSEESSDSSDGEV 560
Query: 2007 ASAAAPAPVST----APATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGL 2062
+A APA + A TS AKG P A + K K + +E+ A
Sbjct: 561 PTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA-- 618
Query: 2063 PPPRAPALPSEARAPHASSLTAAK------RSKAKAKGKEVK---KENRGKGGAVSKLME 2113
APA + A+A A + K + A AK V+ + R G A S
Sbjct: 619 DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGS 678
Query: 2114 SMA-AEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAPRSCIIDKDELKDGLRVLIPMDDK 2172
S A A P +DSS SE+ D +E K GL V +
Sbjct: 679 SPAVAGGTQRPAEDSSSSEES---------------------DSEEEKTGLAVTVGQAKS 717
Query: 2173 LLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAA 2232
+ V+ P V+G G + V P T P T++ A
Sbjct: 718 VGKGLQVKAASVP------VKGSLG-------------QGTAPVLPGKTG--PTVTQVKA 756
Query: 2233 YWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPS 2292
+ ++D + E D + P ++ K Q
Sbjct: 757 -------------------EKQEDSESSEEESDSEEAAASP---AQVKTSVKKTQAKANP 794
Query: 2293 PALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPG----AKARGRGRKPSAKAKGDRAATL 2348
A PSAK GT + PG A A+ + R PS R
Sbjct: 795 AAARAPSAK----------------GTISA--PGKVVTAAAQAKQRSPSKVKPPVR---- 832
Query: 2349 EEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPA 2408
NP + ST LA P+S P K+ + + + + S + +
Sbjct: 833 ---NPQN---STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
Query: 2409 PEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEG 2468
+P + +LAPA + P+K A G GP A K D G
Sbjct: 887 VKPSGKTHQIRAALAPA--------KESPRKGAAPTPPGKTGP-----SAAQAGKQDDSG 933
Query: 2469 VTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQE 2528
+S +S EA PAA +S P
Sbjct: 934 SSSEESDSDGEA-------------------------PAAVTSAQVIKPPLIFVDPNRSP 968
Query: 2529 PGPGLTFEDSGNPKSPDKAQAEQDGAEESESSS--------------------------- 2561
GP T + +P KA+A + A S S S
Sbjct: 969 AGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAH 1028
Query: 2562 -------SSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPAS 2614
S + SSS SS S G + EG + G ++ ++ +
Sbjct: 1029 PRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
Query: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD 2674
++ + SS S SS SSS S + S+ + + S + + +
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE 1148
Query: 2675 EDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHS--------PGKKTPAPQP 2726
+ S DD AP+ + T A QA KA P S K P +
Sbjct: 1149 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1208
Query: 2727 QAPPPQPTQPLQPKA---QAGAKSRPKK----REGVHLPTTKELAKRQRL 2769
+A P Q L PK +A + + P+K ++G P LA + +
Sbjct: 1209 EAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNI 1258
Score = 73.2 bits (178), Expect = 4e-12
Identities = 111/497 (22%), Positives = 175/497 (35%), Gaps = 72/497 (14%)
Query: 2298 PSAKRRSRKTSKDTGEGKDG---GTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPT 2354
P+ + S ++K++ K G G P K AK + + + EEG+ +
Sbjct: 220 PAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSES 279
Query: 2355 DEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKAR--------PAPPQPSPAPPAFTSC 2406
+E P+ T K+ + + RA + A+ PAPP + A + T
Sbjct: 280 EEEA-------PAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA 332
Query: 2407 PAPEPFAELPAPATS-----LAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELL 2461
PE +E + +S A + K + AA + PR+ A
Sbjct: 333 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP-- 390
Query: 2462 VKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKAT 2521
G T P KA+ RE+ +E S PA KAP +A
Sbjct: 391 -----PGKTGPAVAKAQAGK--REEDSQSSSEESDS----EEEAPAQAKPSGKAPQVRAA 439
Query: 2522 DGDLAQEPGPGLTFEDSGNPKSPDKAQAE-QDGAEESESSSSSSSGSSSSSSSSSSSGSE 2580
+ P G P+ A A+ Q G +E +S SSS S + ++ + ++
Sbjct: 440 SAPAKESPRKGAA---PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496
Query: 2581 TE--GEEEGDKNGDG-GCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSS 2637
+ G+ K G G G+ PA+ S+ S SSS SS SS
Sbjct: 497 VKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS 556
Query: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------------SSSTTDEDSSC 2679
++ + + S + + +SS + +S + E+SS
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 616
Query: 2680 SSDDEAAPAPTAGPSAQAALPTKATKQAGK-------ARPSAHSPGKKTPAPQPQAPPPQ 2732
S+D E APA A+ AL TK K A+ + G + P A P
Sbjct: 617 SADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA 676
Query: 2733 PTQPLQPKAQAGAKSRP 2749
+ P A AG RP
Sbjct: 677 GSSP----AVAGGTQRP 689
Score = 68.9 bits (167), Expect = 7e-11
Identities = 257/1238 (20%), Positives = 412/1238 (33%), Gaps = 168/1238 (13%)
Query: 935 ERLKAQEHRAEMEEKGSKRGLEA-AGKAGLATAGPGLLPRKPPGLAAGPA-GTYGKAVSP 992
+R K E +E E+GS+ EA AG A +L + A+ PA GT GK +P
Sbjct: 261 KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRA---ASAPAKGTPGKGATP 317
Query: 993 PPSPRASPVAALKAKVIQKLEDVSK------------PPAYAYPATPSSHPTSPPPASPP 1040
P +A VA+ + K + ED P A A +S TS A+
Sbjct: 318 APPGKAGAVAS-QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASA 376
Query: 1041 PTPGITRKEEAPE-----NVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPY 1095
P RK AP K ++E S + SD P QA P
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436
Query: 1096 PFLLQPTAAADADGLAPDVPL---PADGPERLALSPEDKPIRLSPSKITEPLREGPEEEP 1152
P + G AP P PA ++ ED S S E + E
Sbjct: 437 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED-----SRSSSEE---SDSDREA 488
Query: 1153 LAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQS 1212
LA A+V+ + + P P S + + A P P G G AQ S
Sbjct: 489 LAAMNA-AQVKPLGKSPQVKPA--STMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDS 545
Query: 1213 CAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEEPVEV-PVAVPVV 1271
+ E D +G P +P + + L +P AK P + PVAV V
Sbjct: 546 ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP-----AKGPPQKAGPVAVQVK 600
Query: 1272 EAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQF 1331
P + S E + + A + + P+L+ + T A
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAK-PALKIPQTKACPKKTNTTASAKVAPV 659
Query: 1332 LPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLEQSFLHGITLLS 1391
+ P A + A P G A + + ES E+ +T+
Sbjct: 660 RVGTQAPRKAGTATSPAGSSPAVA-----GGTQRPAEDSSSSEESDSEEEKTGLAVTV-- 712
Query: 1392 EIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDPLKNLRLPRELK 1451
+++ +G + A ++ L G+ + GP V +K
Sbjct: 713 --------GQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK--------- 755
Query: 1452 PNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDS- 1510
E+ +SS E+ D+ E A+V+ K+ Q + R S
Sbjct: 756 -----------AEKQEDSESSEEESDSEEA--AASPAQVKTSVKKTQAKANPAAARAPSA 802
Query: 1511 EDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKS------GHSSGKLSSKSLLTSD 1564
+ P + + + R +PS + PP + ++ G +S K++ T+
Sbjct: 803 KGTISAPGKVVTAAAQAKQR----SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
Query: 1565 DYELG----AGIRKRHKGSEEEHDAL---------------IGMGKARGRNQTWDEHEAS 1605
+ G +G + SEEE + L + K R
Sbjct: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGK 918
Query: 1606 SDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSD---SAGGKSKTSGGC 1662
+ + K+ S E+ S + ++T +K P F D S G + T
Sbjct: 919 TGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQA 978
Query: 1663 GRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSPF 1722
TP RKA A SS T+ + G + P
Sbjct: 979 QAASTP--------RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPR 1030
Query: 1723 ASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGL 1782
+ +S + + S+E + D +GP++ + A + A P+ T
Sbjct: 1031 IAPKASMAGASSSKESSR-ISDGKKQEGPATQVDS--------AVGTLPATSPQST---- 1077
Query: 1783 AAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEA 1842
+++ K ++P +++A SD SE+S D SEE+ E + +
Sbjct: 1078 ----SVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT 1133
Query: 1843 SGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEER 1902
G E S ++A + +L S + P L+ +A + K +
Sbjct: 1134 LVGPTPSRTETLVEETAAESSEDDVVA--PSQSLLSGYMTPGLTPANSQASKATPKLDSS 1191
Query: 1903 QSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAK 1962
S+ T D + + + + + AG+L PK G G+ S P + + +A
Sbjct: 1192 PSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTG-GKEAASGTTPQKSRKPKKGAGNPQAS 1250
Query: 1963 LAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTR-RRSERIFLHDASAAAPAPVSTAPAT 2021
+ + L G P EA +AS + T ER + D T
Sbjct: 1251 TLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVD--------------T 1296
Query: 2022 KTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASS 2081
KG RK +G + PR KKK K+ G G G EA +
Sbjct: 1297 TKESSRKGWESRKRKLSGDQPAARTPRSKKK-KKLGAGEG----------GEASVSPEKT 1345
Query: 2082 LTAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEE 2119
T +K + K KE +GKG S+ + EE
Sbjct: 1346 STTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEE 1383
Score = 65.1 bits (157), Expect = 1e-09
Identities = 94/379 (24%), Positives = 148/379 (39%), Gaps = 40/379 (10%)
Query: 2432 ATRPKPKKARAAEESGAKG-PRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAG 2490
+T ++ AE AK PR + +L G P S K K A E G
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVL------GADLPSSMKEK-AKAETEKAGKT 135
Query: 2491 GWQEP-----KSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPD 2545
G P K++ +L S S+EP A ++ +E G F + P
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE---TEEEGSVPAFGAAAKPGMVS 192
Query: 2546 KAQAEQDGAEESESSSSSS-----SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600
QA+ + S SS + S + +SS S E+ + G G T
Sbjct: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
Query: 2601 NCSAA--SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS-------SSSSSSSSSSS 2651
A + RA P S SS S S + + + S +S ++S+ + +
Sbjct: 253 KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312
Query: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKA---TKQAG 2708
++ + + + +S + + E+ S SS +E++ + P+A+A L KA T Q G
Sbjct: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG 372
Query: 2709 KAR-PSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQ 2767
A P+ SP +K AP PP T P KAQAG + + + +E A Q
Sbjct: 373 AASAPAKESP-RKGAAP----APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE-APAQ 426
Query: 2768 RLPSVENRPKIAAFLPARQ 2786
PS + AA PA++
Sbjct: 427 AKPSGKAPQVRAASAPAKE 445
Score = 64.3 bits (155), Expect = 2e-09
Identities = 328/1618 (20%), Positives = 531/1618 (32%), Gaps = 324/1618 (20%)
Query: 1129 EDKPIRLSPSKITEPLR--EGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAE- 1185
ED ++ +++++P+ E EEE AE E + T L + LP E
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRL--ASTNSSVLGADLPSSMKEK 124
Query: 1186 AMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDL 1245
A A AG G + ATG++ A + + G PR + EP
Sbjct: 125 AKAETEKAGKTGNSMPHP----ATGKTVA------NLLSGKSPRKSA----EPSANT--- 167
Query: 1246 GVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQC 1305
TLV EE +VP A + G+ ++S S D EG+
Sbjct: 168 -------TLVSETEEEG----SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGK- 215
Query: 1306 PSLEP---------------QEAVPVLGSTCFL--------------------EEASSDQ 1330
PS++P ++A P G + E SS++
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 1331 FLPSLEDPLAGMNALAAAAEL---PQARPLPSPGAAGAQALEKLEAAESLVLEQSFLHGI 1387
S E+ AG + A+E +A P+ G G A V Q+
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT----- 330
Query: 1388 TLLSEIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDPLKNLRLP 1447
+ E + E S+E +E A +L A+G P + + P
Sbjct: 331 --KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 388
Query: 1448 RELKPNKKYSWMRKKE--ERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQRELVKLQ 1505
P K + K + +R +SS E+ D+ E E Q K + Q
Sbjct: 389 AP--PGKTGPAVAKAQAGKREEDSQSSSEESDSEE--------EAPAQAKPSGKAP---Q 435
Query: 1506 RRRDSEDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLSS-KSLLTSD 1564
R S +E P + A P PRK A + + ++ S SS + S + L +
Sbjct: 436 VRAASAPAKESPRKGAA---PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAM 492
Query: 1565 DYELGAGIRKRHKGSEEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQE 1624
+ A ++ K + + + +GMG G+ + K A+
Sbjct: 493 N---AAQVKPLGKSPQVKPASTMGMGPL-GKGA------------GPVPPGKVGPATPSA 536
Query: 1625 QLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGL 1684
Q+ ++D S + SDS+ G+ T+ + P A K L
Sbjct: 537 QVGK--------WEEDSESSSEESSDSSDGEVPTA------VAP----------AQEKSL 572
Query: 1685 GLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKD 1744
G L++ + + V + + + +S + E S DS + EE
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS------DSADSEEAPAA 626
Query: 1745 EWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLL 1804
AQ + K+ + C N+ A+ + G APR K ATS
Sbjct: 627 MTAAQAKPALKIPQTKACPKKT-NTTASAKVAPVRVGTQAPR--KAGTATS--------- 674
Query: 1805 REAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESG 1864
A + + + ++ + SSEE D EEE +G +G + +++ GL+
Sbjct: 675 -PAGSSPAVAGGTQRPAEDSSSSEESDSEEE------KTGLAVTVG-QAKSVGKGLQVKA 726
Query: 1865 L-----GLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEV 1919
G L + A LP T GP+++ V KA K+E+ +S ++ ES+
Sbjct: 727 ASVPVKGSLGQGTAPVLPGKT-GPTVTQV------KAEKQEDSES--------SEEESDS 771
Query: 1920 KVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVE--KGRKARKLRGP 1977
+ SPA + K AA P A+G S+P K A K R K++ P
Sbjct: 772 EEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI-SAPGKVVTAAAQAKQRSPSKVKPP 830
Query: 1978 KEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKD 2037
P+ S + A P S K A P +D
Sbjct: 831 VR-----NPQNS------------------TVLARGPASVPSVGKAVATAAQAQTGPEED 867
Query: 2038 AGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEV 2097
+G +++ D ++ + A PS ++L AK S K
Sbjct: 868 SGSSEEESDSEEEAE------------TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915
Query: 2098 KKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAPRSCIIDKD 2157
GK G + + A ++D + D P AV P +D +
Sbjct: 916 P----GKTGPSA----AQAGKQDDSGSSSEESDSDGEAP--AAVTSAQVIKPPLIFVDPN 965
Query: 2158 ELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNR---------PHIYCLEQL 2208
G Q +P R R + P CL
Sbjct: 966 RSPAGPAAT---------PAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPG 1016
Query: 2209 LQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGD 2268
++ ++ + A R P+ + A S++ + G + +G V D
Sbjct: 1017 IRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGK--------KQEGPATQV---DSA 1065
Query: 2269 TGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKT----SKDTGEGKDGGTAGSEE 2324
G +P + P +Q A+ + L P + T S D E ++GSEE
Sbjct: 1066 VGTLPATS----PQSTSVQ-AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEE 1120
Query: 2325 PGAKARGR-------GRKPSAKAKGDRAATLEEGNPTDEVPSTPL-------ALEPSSTP 2370
G +G G PS E PS L L P+++
Sbjct: 1121 DGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQ 1180
Query: 2371 GSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITM 2430
SK +P +D A P A P+ A + +P T A T
Sbjct: 1181 ASKATPK--LDSSPSVSSTLAAKDDPDGKQEA-----KPQQAAGMLSPKTGGKEAASGTT 1233
Query: 2431 PATRPKPKKARAAEESGAK-----------GPRRPGEEAELLVKLDHEGVTSPKSKKAKE 2479
P KPKK ++ G P EA++ + + +T ++ K+
Sbjct: 1234 PQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV-KVLTELLEQERKK 1292
Query: 2480 ALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSG 2539
+ ++ GW+ K LS G P A + P K A E G +
Sbjct: 1293 VVDTTKESSRKGWESRKRKLS-GDQPAA------RTPRSKKKKKLGAGEGGEASVSPEKT 1345
Query: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT-G 2598
+ S KA+ ++ + E S GS G++ E EEE K G GT
Sbjct: 1346 STTSKGKAKRDKASGDVKEKKGKGSLGSQ---------GAKDEPEEELQK----GMGTVE 1392
Query: 2599 GRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
G + S S+ S + +S+ S S S ++ +
Sbjct: 1393 GGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450
Score = 61.2 bits (147), Expect = 1e-08
Identities = 108/480 (22%), Positives = 182/480 (37%), Gaps = 67/480 (13%)
Query: 1706 EVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMV 1765
E+G K + + +A + VS ++S E+EE + E P + S+L + +
Sbjct: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADL 117
Query: 1766 AKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLR------EAEARSSFSDSSEE 1819
+ K + K G P PAT + L + E A ++ +EE
Sbjct: 118 PSSMKEKAKAETEKAGKTG--NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
Query: 1820 ----------------SFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEES 1863
S Q +SS E+ +E + G A+ +A S +ES
Sbjct: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSS--SDETDVEGKPSVKPAQVKASSVSTKES 233
Query: 1864 GLGLLARFAASALPSP----TVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEV 1919
A A P+P V P + L ++A+K EE +E SESE
Sbjct: 234 P-------ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEE-----SESSEEGSESEE 281
Query: 1920 KVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKE 1979
+ + + + +K L S A +G P+ P KA AV KA K P+E
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG-AVASQTKAGK---PEE 337
Query: 1980 PGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSR-------CAKGGPL 2032
+ E+SD + T + + + ++APA ++ R K GP
Sbjct: 338 DSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPA 397
Query: 2033 SPRKDAG-RAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAK 2091
+ AG R +D + ++ +E P P +AP + RA A + + ++ A
Sbjct: 398 VAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP----QVRAASAPAKESPRKGAAP 453
Query: 2092 AKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVE-RPLTPAPR 2150
A + K G + ++ EED + + S S+ E L A + +PL +P+
Sbjct: 454 APPR--------KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 505
Score = 60.5 bits (145), Expect = 2e-08
Identities = 101/474 (21%), Positives = 167/474 (35%), Gaps = 63/474 (13%)
Query: 2354 TDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFA 2413
T E+ A E ++ K +P+ + + A + + A P S + A
Sbjct: 56 TSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGA 115
Query: 2414 ELPAPATSLAPAPLITMPAT---RPKPKKARA-AEESGAKGPRR---PGEEAELLVKLDH 2466
+LP+ A A T P P + A K PR+ P L+ + +
Sbjct: 116 DLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
Query: 2467 EG-------VTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPA----AGSSEPKA 2515
EG P A +A ED + + + S PA + S ++
Sbjct: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSS--DETDVEGKPSVKPAQVKASSVSTKES 233
Query: 2516 PWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSS 2575
P KA P PG + + K A++ E ES SS GS S + +
Sbjct: 234 PARKAA-------PAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE-GSESEEEAPA 285
Query: 2576 SSGSETEGEEE--------GDKNGDGGCGT-----GGRNCSAASSRAASPASSSSSSSSS 2622
+ S+ + E+ G G G G A+ ++A P S SSS
Sbjct: 286 GTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE 345
Query: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----------SSSSST 2672
SS S + ++ + + +S +S ++S+ + S ++ + + +
Sbjct: 346 SSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK 405
Query: 2673 TDEDSSCSSD--DEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPP 2730
+EDS SS+ D AP AQA KA + + P+ SP +K AP P
Sbjct: 406 REEDSQSSSEESDSEEEAP-----AQAKPSGKAPQVRAASAPAKESP-RKGAAP----AP 455
Query: 2731 PQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPA 2784
P+ T P + Q G + + + +E V+ K PA
Sbjct: 456 PRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 509
Score = 58.5 bits (140), Expect = 9e-08
Identities = 120/569 (21%), Positives = 189/569 (33%), Gaps = 71/569 (12%)
Query: 181 PSARTPGGGHSSGAPAKGSSSRDGPAKERAG------RGGEPPPLFGKKDPRARGEEASG 234
PS + SS + + + + PA + G +GG PP K P EE+
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPE---EESES 272
Query: 235 PRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDV--- 291
+ +EA A R + +E++ A S G AG V
Sbjct: 273 SEEGSESEEEAPAGTRSQ---VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 329
Query: 292 ---GLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGP-PA 347
G P +E+ + ++ + A+ L + + + + P +P KG PA
Sbjct: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 389
Query: 348 PPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRP 407
PP T V + E + S E + P A Q R A A +E+ R
Sbjct: 390 PPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK 449
Query: 408 GVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLK 467
G APP P + ++ RS +D + A A+ K L K
Sbjct: 450 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ-------VKPLGK 502
Query: 468 PEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLA 527
+P GP G A + PG+ P P ++G + +
Sbjct: 503 -SPQVKPASTMGMGPLGKGAGP------VPPGKVGPATPSA-----QVGKWEEDSESSSE 550
Query: 528 AQHHHSRAEEEAAVVAASSSK-------KAYLDPGAVLPRSAATCG------RPVADMHS 574
S E AV A K P P+ A +P+ + S
Sbjct: 551 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES 610
Query: 575 AAHGSGEASAMQSLIKYSGSFARDAVAV-RPGGCGKKSPFGGLGTMKPEPAPTSAGASRA 633
+ S A + ++ + + A+ A+ + + C KK+ + P T A
Sbjct: 611 SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAG 670
Query: 634 QARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKD 693
A P PA GG Q RP E S + E++ G+AV V + K
Sbjct: 671 TATSPAGSSPAVAGGTQ------RP-------AEDSSSSEESDSEEEKTGLAVTVGQAKS 717
Query: 694 SGGSGRLGPGLVDQERSLSLSNVKGHGRA 722
+G GL + S+ + G G A
Sbjct: 718 ------VGKGLQVKAASVPVKGSLGQGTA 740
Score = 57.8 bits (138), Expect = 2e-07
Identities = 114/534 (21%), Positives = 182/534 (34%), Gaps = 84/534 (15%)
Query: 2291 PSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSE---EPGAKARGRGRKPSAKAKGDRAAT 2347
P PA A S K+ + + E T SE E A G KP + G ++
Sbjct: 140 PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSS 199
Query: 2348 LEE-GNPTDEV-----PSTPLALEPSSTPGSKKSP-----PEP-----VDKRAKAPKARP 2391
E+ + +DE PS A +S+ +K+SP P P V + K P
Sbjct: 200 SEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP 259
Query: 2392 APPQPSPAPPAFTSCPAPEPFAELPAPATS------------LAPAPLITMP---ATRPK 2436
A P + +S E E PA S A AP P AT
Sbjct: 260 AKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAP 319
Query: 2437 PKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPK 2496
P KA A G +P E++E E S + A +ALL + G
Sbjct: 320 PGKAGAVASQTKAG--KPEEDSE---SSSEESSDSEEETPAAKALLQAKASGK------T 368
Query: 2497 SLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEE 2556
S + S P + AP P + GP + +G + ++ +E+ +EE
Sbjct: 369 SQVGAASAPAKESPRKGAAPAPPG-------KTGPAVAKAQAGKREEDSQSSSEESDSEE 421
Query: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616
+ + SG + ++S+ E+ + G R A+++
Sbjct: 422 EAPAQAKPSGKAPQVRAASAPAKESPRK--------GAAPAPPRKTGPAAAQVQVGKQEE 473
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------------SS 2658
S SSS S S + ++ +++ S +S+ ++
Sbjct: 474 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
Query: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDE--AAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
S+ S ++ E+SS SSD E A AP S L K T K P
Sbjct: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG 593
Query: 2717 P---GKKTPAPQPQAPPPQPTQPLQPKAQA-GAKSRPKKREGVHLPTTKELAKR 2766
P K P + + + +A A + + + + +P TK K+
Sbjct: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
Score = 51.2 bits (121), Expect = 1e-05
Identities = 87/363 (23%), Positives = 129/363 (35%), Gaps = 57/363 (15%)
Query: 944 AEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAA 1003
+E EE+GS AA K G+ +AG + ++ GK P +AS V+
Sbjct: 171 SETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVST 230
Query: 1004 LKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLEL 1063
++ + P TP + PPA P EE E+ E + E
Sbjct: 231 KESPA----RKAAPAPGKVGDVTPQVKGGALPPAKRAKKP-----EEESESSEEGSESEE 281
Query: 1064 EKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPER 1123
E A + Q S+ L A+A A G PA +
Sbjct: 282 EAPAGTRSQVKASE------------------KILQVRAASAPAKGTPGKGATPAPPGKA 323
Query: 1124 LALSPE---DKPIRLSPSKITEPLREGPEEEPLAER--EVKAEVEDMDEGPTELPPLESP 1178
A++ + KP S S +E + EE P A+ + KA + G P ESP
Sbjct: 324 GAVASQTKAGKPEEDSESS-SEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESP 382
Query: 1179 LPLPAAEAMATPSPAGGCGGGLLEAQA--LSATGQSCAEPSECPDFVEGPEPRVDSPGRT 1236
A P+P G G + +AQA QS +E S+ + ++P +
Sbjct: 383 ------RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE---------EAPAQA 427
Query: 1237 EPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSE--SQPTLEMS 1294
+P A + P AKE P + P + P QV E S+ + E S
Sbjct: 428 KPSGKAPQVRAASAP-----AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 482
Query: 1295 DCD 1297
D D
Sbjct: 483 DSD 485
Score = 48.9 bits (115), Expect = 7e-05
Identities = 251/1286 (19%), Positives = 428/1286 (33%), Gaps = 226/1286 (17%)
Query: 917 QQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPP 976
+ A QA + + S + +E AE E + L + + L P + K
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 977 GLAAGPAGTYGKAVSPPP------------SPRASPVAALKAKVIQKLEDVSKPPAYAYP 1024
AG G ++ P SPR S + ++ + E+ PA+
Sbjct: 127 A-ETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
Query: 1025 ATPSSHPTSPPPASPPPTPGIT-----------RKEEAPENVVEKKDLELEKEAPSPFQA 1073
A P +S T + + + + V K+ K AP+P +
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
Query: 1074 LFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPE---- 1129
D+ P+ ALPP P + + + +G + PA ++ S +
Sbjct: 246 --GDVTPQVKGGALPPAKRAKKP---EEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 1130 ---DKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEA 1186
P + +P K P G ++ + ED + E +S PAA+A
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE--SSDSEEETPAAKA 358
Query: 1187 MATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLG 1246
+ +G S G + A E P P P PG+T P A G
Sbjct: 359 LLQAKASG----------KTSQVGAASAPAKESPRKGAAPAP----PGKTGPAVAKAQAG 404
Query: 1247 VQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGE---- 1302
+ ++ ++E E EE AQ PS P ++ PA E
Sbjct: 405 -KREEDSQSSSEESDSE------------EEAPAQAKPSGKAP--QVRAASAPAKESPRK 449
Query: 1303 GQCPSLEPQEAVPVLGSTCF----LEEASSDQFLPSLEDPLAGMNA--LAAAAELPQARP 1356
G P+ P++ P + SS + S + LA MNA + + PQ +P
Sbjct: 450 GAAPA-PPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
Query: 1357 LPSPG----AAGAQALEKLEAAESLVLEQSFLHGITLLSEIAELELERRSQEMGGAERAL 1412
+ G GA + + + Q + E +E E S G
Sbjct: 509 ASTMGMGPLGKGAGPVPPGKVGPATPSAQ-----VGKWEEDSESSSEESSDSSDGEVPTA 563
Query: 1413 VARPSLESLLAAGSHMLREVLDGPVVDPLKNLRLPRELKPNKKYSWMRKKEERMYAMKSS 1472
VA +SL G+ + + P P P++ P K + + + S
Sbjct: 564 VAPAQEKSL---GNILQAKPTSSPAKGP------PQKAGPVAVQVKAEKPMDNSESSEES 614
Query: 1473 LEDMDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDSEDRREEPHRSLARRGPGRPRKR 1532
+ D+ E M A+ + K Q + ++ + + P R G PRK
Sbjct: 615 SDSADSEEAPAAMTAAQAKPALKIPQTKACP-KKTNTTASAKVAP----VRVGTQAPRKA 669
Query: 1533 THA--PSALSP--------PRKRGKSGHSSGKLSSK---SLLTSDDYELGAGIRKRH--- 1576
A P+ SP P + S S K ++ +G G++ +
Sbjct: 670 GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASV 729
Query: 1577 --KGSEEEHDALIGMGKARGRNQTWDEHEASSDF-ISQLKIKKKKMASDQEQLASKLDKA 1633
KGS + A + GK G T + E D S+ + ++ A+ Q+ + + K
Sbjct: 730 PVKGSLGQGTAPVLPGKT-GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
Query: 1634 LSLTKQDKLKSP-FKFSDSAGGKSKTSGGCGRYLTPY----DSLLGKNRKALAKG----- 1683
+ ++P K + SA GK T+ + +P +N LA+G
Sbjct: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
Query: 1684 -LGLSLKSSREGKH-------------------------KRAAKTRKMEVGF-KARGQPK 1716
+G ++ ++ + + K + KT ++ A+ P+
Sbjct: 849 SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPR 908
Query: 1717 SAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPK 1776
+P + S ++D+ E + S + ++ + V K P
Sbjct: 909 KGAAPTPPGKTGPSAAQAGKQDDSGSSSE---ESDSDGEAPAAVTSAQVIKPPLIFVDPN 965
Query: 1777 LTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEEL 1836
+ G AA P A + P E+ ARSS S+S +E +
Sbjct: 966 RSPAGPAA----TPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 1021
Query: 1837 --------EEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVV 1888
+AS G +S G ++ G A LP+ P + V
Sbjct: 1022 VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPA--TSPQSTSV 1079
Query: 1889 QLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTP 1948
Q + K RK + + T+ + +SE S + + GE GP A
Sbjct: 1080 QAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGS------EEDGE-GPQGAKSAH 1132
Query: 1949 GARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRS-------ER 2001
GP PS + + VE E E+S+DD+ +S
Sbjct: 1133 TLVGPTPS---RTETLVE----------------ETAAESSEDDVVAPSQSLLSGYMTPG 1173
Query: 2002 IFLHDASAAAPAP-VSTAPATKTSRCAKGGP--------------LSPRKDAGRAKDRKD 2046
+ ++ A+ P + ++P+ ++ AK P LSP+ A
Sbjct: 1174 LTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTT 1233
Query: 2047 PRKKKKGKEAGPGAGLPPPRAPALPS 2072
P+K +K K+ GAG P AL S
Sbjct: 1234 PQKSRKPKK---GAGNPQASTLALQS 1256
Score = 46.2 bits (108), Expect = 5e-04
Identities = 107/495 (21%), Positives = 162/495 (32%), Gaps = 79/495 (15%)
Query: 170 AGAPGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFG---KKDPR 226
AG G+ H + +T S +P K + P FG K
Sbjct: 132 AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 227 ARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPS----VLT 282
+ G+ S + E EG+ P ++ + S ES + AA P V
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEGKPSVKPAQV-KASSVSTKESPARKAAPAPGKVGDVTP 250
Query: 283 MCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTET------LLPGPRPCPSPLP 336
GGA A E ++E + +E A R++ L P+
Sbjct: 251 QVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGT 310
Query: 337 P----PPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIAS 392
P PAPP A + T AG E E + P+ +A + + S
Sbjct: 311 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGK-TS 369
Query: 393 QARDARAREREAGRPGVLQAPPGSPRPL--DRPEGLREKNSVIRSLKRPPPADAPTVRAT 450
Q A A +E+ R G APPG P G RE++S S + +AP
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP----- 424
Query: 451 RASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKW 510
A +P +AP+ A A + + G P P TGP
Sbjct: 425 -------------------AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGP---- 461
Query: 511 KPFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVA 570
AA Q+ V Q SR+ E + + A ++ V P + +P +
Sbjct: 462 --------AAAQVQV-GKQEEDSRSSSEES--DSDREALAAMNAAQVKPLGKSPQVKPAS 510
Query: 571 DMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAPTSAGA 630
M G G A V PG G +P +G + + +S +
Sbjct: 511 TMGMGPLGKG------------------AGPVPPGKVGPATPSAQVGKWEEDSESSSEES 552
Query: 631 S-RAQARLPHSGGPA 644
S + +P + PA
Sbjct: 553 SDSSDGEVPTAVAPA 567
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 87.0 bits (214), Expect = 2e-16
Identities = 68/163 (41%), Positives = 88/163 (53%), Gaps = 14/163 (8%)
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDED 2676
S +SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS+S S +
Sbjct: 145 SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHK 204
Query: 2677 SSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT--------PAPQPQA 2728
S D + PS K++K++ K +P + P K+ P+P +
Sbjct: 205 EKPSKDSREHKSAFKEPSRD---HNKSSKESSK-KPKENKPLKEEKIVPKMAFKEPKPMS 260
Query: 2729 PPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPS 2771
P+P L K P KR + ++EL+ ++R S
Sbjct: 261 KEPKPDSNLLTITSGQDKKAPSKRPPI--SDSEELSAKKRKKS 301
Score = 45.8 bits (107), Expect = 6e-04
Identities = 70/300 (23%), Positives = 110/300 (36%), Gaps = 45/300 (15%)
Query: 2430 MPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGA 2489
M + KP K +S K P R DH + SKK KE L+E+
Sbjct: 200 MKEHKEKPSKDSREHKSAFKEPSR-----------DHNKSSKESSKKPKENKPLKEE--- 245
Query: 2490 GGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDK--- 2546
K + + P S EPK D +L LT + K+P K
Sbjct: 246 ------KIVPKMAFKEPKPMSKEPKP------DSNL-------LTITSGQDKKAPSKRPP 286
Query: 2547 -AQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAA 2605
+ +E+ A++ + SSS + S SS+ + ++ DK+ + ++
Sbjct: 287 ISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSE 346
Query: 2606 SSRAASPA-------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2658
++ P + S + SS S S S +SSSSSSSSS + S + S
Sbjct: 347 KKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSI 406
Query: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKA-RPSAHSP 2717
S + S ED+ S+ E S + +L + ++ A P H P
Sbjct: 407 MKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEP 466
Score = 42.4 bits (98), Expect = 0.007
Identities = 45/214 (21%), Positives = 76/214 (35%), Gaps = 15/214 (7%)
Query: 2528 EPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEG 2587
+P + S + S + + + S SSSSSSS SSSSSSSSSSS S ++ +
Sbjct: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLM 200
Query: 2588 DKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSS---------------SSSSSS 2632
++ + + SA + SS SS + S
Sbjct: 201 KEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMS 260
Query: 2633 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG 2692
S+ + +S + S S S S+ + ++ S A P
Sbjct: 261 KEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTC 320
Query: 2693 PSAQAALPTKATKQAGKARPSAHSPGKKTPAPQP 2726
+ + + K+ + GK + + + KK P
Sbjct: 321 SADKKQIKDKSHVKMGKVKIESETSEKKKSTLPP 354
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 87.0 bits (214), Expect = 2e-16
Identities = 65/158 (41%), Positives = 82/158 (51%), Gaps = 18/158 (11%)
Query: 2546 KAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEG---EEEGDKNGDGGCGTGGRNC 2602
K ++E E S S S + + S S G + GD+ G C T R
Sbjct: 2046 KVKSENLKEEPQSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMV 2105
Query: 2603 SAASS---------------RAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
+A + R + +S S S S SS SS SSSSSSSSS S S S SSS
Sbjct: 2106 AARTEPLTPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSS 2165
Query: 2648 SSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEA 2685
SSSSS SS+SSSSSSS+SSSSSSS++ + S S ++EA
Sbjct: 2166 SSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEA 2203
Score = 77.8 bits (190), Expect = 1e-13
Identities = 57/148 (38%), Positives = 74/148 (50%), Gaps = 21/148 (14%)
Query: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599
NP S K + + G+E S S S S SS SS SSSSS S +
Sbjct: 2115 NPASK-KPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSS------------------ 2155
Query: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2659
CS + S ++S +SSS SS+SSSSSSS+SSSSSSSSSSS S S + S++
Sbjct: 2156 --CSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMK 2213
Query: 2660 SSSSSSSSSSSSTTDEDSSCSSDDEAAP 2687
+ S +S S+T DE + P
Sbjct: 2214 AYDEESVASLSTTQDETQDSFQMNNGTP 2241
Score = 75.1 bits (183), Expect = 1e-12
Identities = 62/158 (39%), Positives = 81/158 (51%), Gaps = 21/158 (13%)
Query: 2529 PGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGD 2588
P G+ + +G+ KS K E D + + + +S GSE+ + + D
Sbjct: 2080 PKNGVLPQATGDQKSGGKC--ETDRRMVAARTEPLTPNPASKKPRVHKRGSESSSDSDSD 2137
Query: 2589 KNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
S+ SSR++S SSSSSS S S S SSSSSSSS SS+SSSSSSS+SS
Sbjct: 2138 SER-----------SSCSSRSSS--SSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSS 2184
Query: 2649 SSSSSSSSSSSSSSSSSSSSSSSTT------DEDSSCS 2680
SSSSSSSSS S S + +T DE+S S
Sbjct: 2185 SSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEESVAS 2222
Score = 65.5 bits (158), Expect = 8e-10
Identities = 51/164 (31%), Positives = 72/164 (43%), Gaps = 4/164 (2%)
Query: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTG----GRNCSAASSRAAS 2611
+SE+ S S SS + + + E KNG TG G C A+
Sbjct: 2048 KSENLKEEPQSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAA 2107
Query: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
+ + +S S SSS S S S SS SS SSSSSSSSS S S S SSSSS
Sbjct: 2108 RTEPLTPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSS 2167
Query: 2672 TTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAH 2715
++ S+ SS + + ++ S+ + ++A K + H
Sbjct: 2168 SSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTH 2211
Score = 42.7 bits (99), Expect = 0.005
Identities = 39/162 (24%), Positives = 57/162 (35%), Gaps = 15/162 (9%)
Query: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNG----- 2591
+SG E +G E S SS +G +S SSS S+ S N
Sbjct: 2720 ESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPSTSSTAALNTAAAANPLALNP 2779
Query: 2592 --------DGGCGTGGRN--CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641
G T G N S + +S SS S S
Sbjct: 2780 LLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLGSSKSVEVKEEDSRIKDQEDK 2839
Query: 2642 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDD 2683
+ S + +S+ S + +SS S S+S++ EDS S++D
Sbjct: 2840 GGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSNED 2881
Score = 39.3 bits (90), Expect = 0.059
Identities = 25/97 (25%), Positives = 43/97 (44%)
Query: 2538 SGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT 2597
S + S + + + S SS SS+S SSSSS+SSSSS S + EE +
Sbjct: 2148 SSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRE 2207
Query: 2598 GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSS 2634
+ A + + S++ + S ++ + S+
Sbjct: 2208 STTHMKAYDEESVASLSTTQDETQDSFQMNNGTPESA 2244
Score = 32.7 bits (73), Expect = 5.5
Identities = 16/42 (38%), Positives = 25/42 (59%)
Query: 2536 EDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSS 2577
+ G SP + +G+E++++SS S S SSSS S SS+
Sbjct: 2838 DKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2879
Score = 32.0 bits (71), Expect = 9.4
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 5/66 (7%)
Query: 2522 DGDLAQEPGPGLTFEDSGNPKSPDKAQAE-----QDGAEESESSSSSSSGSSSSSSSSSS 2576
+ DL + EDS DK E ++ +E + +SSGS S+SSSS
Sbjct: 2815 NSDLGSSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSED 2874
Query: 2577 SGSETE 2582
S S E
Sbjct: 2875 SDSSNE 2880
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 85.9 bits (211), Expect = 5e-16
Identities = 97/366 (26%), Positives = 145/366 (39%), Gaps = 52/366 (14%)
Query: 2405 SCPAPEPFAELPAPATSLAPAPLITMPA--------TRPKPKKARAAEESGAKGPRRPGE 2456
S P+P+ + LP S P T P+ K K + + PR+ E
Sbjct: 152 SRPSPD-YPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSE 210
Query: 2457 EAELLVKLDHEGVTSPK--SKKAKEALLLRED---PGAGGWQEPKSLLS---LGSYPPAA 2508
+L+ E S K S+K E L +E+ P ++EPK L L S P
Sbjct: 211 SKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKG 270
Query: 2509 GSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSS 2568
G P P P+A+ K P A + + A++ + SSS S S+
Sbjct: 271 GPPPPPPPPPRASS-------------------KRPATADSPKPSAKKQKKSSSKGSRSA 311
Query: 2569 SSSSS-SSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSS 2627
+S +SSS S ++ + DK+ T G A S + + S+S +S
Sbjct: 312 PGTSPRTSSSSSFSDKKPAKDKSS-----TRGEKVKAESEPREAKKALEVEESNSEDEAS 366
Query: 2628 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSSTTDEDSSCSSDDEA 2685
S S+ SS S+SSSSS SSS S S + S S S +DED S S ++ A
Sbjct: 367 FKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAA 426
Query: 2686 APAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGA 2745
S + +++ A + PS P PQ PPP P + + +
Sbjct: 427 GKTNPGRDSRLSFSDSESDNSADSSLPSRE-------PPPPQKPPP-PNSKVSGRRSPES 478
Query: 2746 KSRPKK 2751
S+P+K
Sbjct: 479 CSKPEK 484
Score = 55.1 bits (131), Expect = 1e-06
Identities = 95/417 (22%), Positives = 137/417 (32%), Gaps = 97/417 (23%)
Query: 2282 PDYKIQCAEPSPALLVPS----------AKRRSRKTSKDTGEGKDGGTAGSEEPGAKARG 2331
PDY + P A P A + S KTSK K+ ++ +K+
Sbjct: 156 PDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSS 215
Query: 2332 RG-RKPSAKAKGDRAATLEEGN-PTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKA 2389
+ + AK+ D + L EG P +E P A K++ E + P
Sbjct: 216 KELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPP 275
Query: 2390 RPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAK 2449
P PP+ S PA P P A+ ++S +K
Sbjct: 276 PPPPPRASSKRPATADSPKP-----------------------------SAKKQKKSSSK 306
Query: 2450 GPR-RPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAA 2508
G R PG TSP++ + S PA
Sbjct: 307 GSRSAPG--------------TSPRTSSSS---------------------SFSDKKPAK 331
Query: 2509 GSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSS 2568
S + KA +E L E+S S D+A + + A+ S S+SSSSS SS
Sbjct: 332 DKSSTRGEKVKAESE--PREAKKALEVEES---NSEDEASFKSESAQSSPSNSSSSSDSS 386
Query: 2569 SSS----SSSSSSG------SETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSS 2618
S S S + S G + + EE + + G G+ SR S S
Sbjct: 387 SDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRL-----SFSD 441
Query: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
S S +S+ SS S +S S S S S + + TDE
Sbjct: 442 SESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDE 498
Score = 39.7 bits (91), Expect = 0.045
Identities = 32/148 (21%), Positives = 50/148 (33%), Gaps = 2/148 (1%)
Query: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD 2674
S+ S + S S ++ SS +S + S S SSS + +
Sbjct: 167 SAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSS 226
Query: 2675 EDSSCSSDDEAAPAPTAGPSAQAAL--PTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQ 2732
+D+S + P P +AA P A K+ S P P P+A +
Sbjct: 227 KDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKR 286
Query: 2733 PTQPLQPKAQAGAKSRPKKREGVHLPTT 2760
P PK A + + + P T
Sbjct: 287 PATADSPKPSAKKQKKSSSKGSRSAPGT 314
Score = 35.4 bits (80), Expect = 0.85
Identities = 40/187 (21%), Positives = 73/187 (39%), Gaps = 26/187 (13%)
Query: 1959 DKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTA 2018
++AK + + RK + R PKE P+A+ + + ++ P P
Sbjct: 221 EQAKSSKDTSRKLGEGRLPKEEKAPP-PKAAFKEPKMALKETKLESTSPKGGPPPPPPPP 279
Query: 2019 PATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPH 2078
P + R A SP+ A +K + KG + PG P + + S+ +
Sbjct: 280 PRASSKRPATAD--SPKPSA-----KKQKKSSSKGSRSAPGTS-PRTSSSSSFSDKKPAK 331
Query: 2079 ASSLTAAKRSKAKAKGKEVKK-----------------ENRGKGGAVSKLMESMAAEEDF 2121
S T ++ KA+++ +E KK E+ + S +++ DF
Sbjct: 332 DKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDF 391
Query: 2122 EPNQDSS 2128
EP+Q+ S
Sbjct: 392 EPSQNHS 398
Score = 34.7 bits (78), Expect = 1.4
Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 21/133 (15%)
Query: 218 PLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQ 277
P G KD + S P V T+E R R+D +ESK+ + L+
Sbjct: 177 PSHGSKDANKESSKTSKPHKV---TKEHRERPRKD--------------SESKSSSKELE 219
Query: 278 PSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPP 337
+ +G L E K A ++ + A ET L P P PP
Sbjct: 220 REQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMAL----KETKLESTSPKGGPPPP 275
Query: 338 PPAPPKGPPAPPA 350
PP PP+ PA
Sbjct: 276 PPPPPRASSKRPA 288
Score = 33.9 bits (76), Expect = 2.5
Identities = 89/397 (22%), Positives = 141/397 (35%), Gaps = 84/397 (21%)
Query: 1520 SLARRGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLSSKSLLTSDDYELGAGIRKRHKGS 1579
+++R P P T SA S P+K K H S + +S TS +++ R+R +
Sbjct: 150 TVSRPSPDYPMLPTIPLSAFSDPKKT-KPSHGSKDANKESSKTSKPHKVTKEHRERPRKD 208
Query: 1580 EEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDKALSLTKQ 1639
E + K R Q + S + + ++ K++ A + + AL K+
Sbjct: 209 SESKSS----SKELEREQAKSSKDTSRK-LGEGRLPKEEKAPPPKAAFKEPKMAL---KE 260
Query: 1640 DKLKSPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRA 1699
KL+S + GG P R A A K +
Sbjct: 261 TKLES----TSPKGGPPPPP--------PPPPRASSKRPATADS------------PKPS 296
Query: 1700 AKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPS 1759
AK +K +R P + SP S SS+S D+ PA+ SS++
Sbjct: 297 AKKQKKSSSKGSRSAPGT--SPRTSSSSSFS-------------DKKPAKDKSSTR---- 337
Query: 1760 LLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEE 1819
+ KA P+ K+ L + A+ + + + S+ S SS+
Sbjct: 338 ------GEKVKAESEPREAKKALEVEESNSEDEASFKSES------AQSSPSNSSSSSDS 385
Query: 1820 SFDQD------------ESSEEEDEEEELEEEDEASG---GGYRLGARERALSPGLEESG 1864
S D D S E+ + EE +E+D +SG G R+ LS ES
Sbjct: 386 SSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESD 445
Query: 1865 LGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEE 1901
A S+LPS P +K R+ E
Sbjct: 446 -----NSADSSLPSREPPPPQKPPPPNSKVSGRRSPE 477
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 85.1 bits (209), Expect = 9e-16
Identities = 116/473 (24%), Positives = 178/473 (37%), Gaps = 49/473 (10%)
Query: 2339 KAKGDRAATLEEGN----PTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPP 2394
K + LE G +E + LA + SP E ++ K+ +
Sbjct: 325 KTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKS 384
Query: 2395 QPSPAPPAFTSCPAPEPFAELPAPATSL--APAPLITMPATRPKPKKARAAEES--GAKG 2450
+ SP+PP T LP S P PL+T A+ P P +EE +G
Sbjct: 385 K-SPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEG 443
Query: 2451 PRRP-----------GEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLL 2499
P P + ELLV + S + + E P +E S+L
Sbjct: 444 PAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEE--SVL 501
Query: 2500 SLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESES 2559
L A S K P++ D + +P P L E+ K + +Q E+ E
Sbjct: 502 PLVQKSTLADYSAQKDLEPES---DRSAQPLP-LKIEELALAKGITEECLKQPSLEQKEG 557
Query: 2560 --------------SSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAA 2605
S+ SS S SSSSSSSSS S + + + R+ + A
Sbjct: 558 RRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQA 617
Query: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665
+ A S S+S S S S S S S+SS+S S S S SS+S + + SS
Sbjct: 618 RTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSG 677
Query: 2666 SSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQ-AGKARPSAHSPGKKTPAP 2724
++ + C + + + ++ + + + P A K + +P SP K
Sbjct: 678 QEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKK---CE 734
Query: 2725 QPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPK 2777
+A PP TQP + Q S + E +H T E + + + ENRP+
Sbjct: 735 AEEAEPPAATQPQTSETQT---SHLPESERIH--HTVEEKEEVTMDTSENRPE 782
Score = 62.4 bits (150), Expect = 6e-09
Identities = 123/566 (21%), Positives = 196/566 (34%), Gaps = 83/566 (14%)
Query: 2279 LLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSA 2338
LLPPD++ P L S R+S S++ G+ D E+P +G + S+
Sbjct: 182 LLPPDFQSSLERPELELSRHSP-RKSSSISEEKGDSDD------EKPR-----KGERRSS 229
Query: 2339 KAKGDRAATLEEGN-PTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPS 2397
+ + RAA L EG+ P +E + E ++ + + +
Sbjct: 230 RVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGD 289
Query: 2398 PAPPAFTSCPAPEPFAELPAPATSLAPAPLI-TMPATRPKPKK--------ARAAEESGA 2448
P + F E + P ++ P TR + ++ R+ EE+
Sbjct: 290 DEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARK 349
Query: 2449 KGPRRPGEEAELLV--KLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPP 2506
R +E E+ L+ E S+ KE P ++ SL++L P
Sbjct: 350 SHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVAL----P 405
Query: 2507 AAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPD------KAQAEQDGAEESESS 2560
+SE + P P T + P P L E+ P + A+ E
Sbjct: 406 EQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELL 465
Query: 2561 SSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGC-----------GTGGRNCSAASSRA 2609
S + S SS S+T+ E +K + + ++ S R+
Sbjct: 466 VSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRS 525
Query: 2610 ASP--------------ASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2655
A P S +S + S S+ SSSS SSSSS
Sbjct: 526 AQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSS 585
Query: 2656 SSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQA-GKARP-- 2712
SSSS S S S SS S + D A A P + + +++T ++ ++R
Sbjct: 586 SSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRS 645
Query: 2713 -SAHSPGKKTPAP-------------------QPQAPPPQP-TQPLQPKAQAGAKSRPKK 2751
SA S +K+ +P Q A PP P Q +PK + S +
Sbjct: 646 RSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQ 705
Query: 2752 REGVHLPTTKELAKRQRLPSVENRPK 2777
+ P + E QRL PK
Sbjct: 706 ARRLSQPESAEKHVTQRLQPERGSPK 731
Score = 40.4 bits (93), Expect = 0.026
Identities = 38/130 (29%), Positives = 50/130 (38%), Gaps = 28/130 (21%)
Query: 332 PSPLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIA 391
P PL PPP PP PP P A EQ + R V E + ER +
Sbjct: 1114 PRPLHPPPPPPVQPPQHPRA----------EQREQERAVR-------EQWAER----ERE 1152
Query: 392 SQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTV---- 447
+ R+ ERE R V + P R DR R K+ +S K+ + P
Sbjct: 1153 MERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLD 1212
Query: 448 ---RATRASP 454
R T+A+P
Sbjct: 1213 DLFRKTKAAP 1222
Score = 34.7 bits (78), Expect = 1.4
Identities = 45/169 (26%), Positives = 62/169 (36%), Gaps = 20/169 (11%)
Query: 1028 SSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYP---- 1083
SS SP P P +T + V + E+E P P + PP +P
Sbjct: 376 SSQGLKEKSKSPSP-PRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHS 434
Query: 1084 FQALPPHYGRPYPFLLQ---PTAAADADGLAPDVPLPADGPERL--ALSPEDKPIRLSPS 1138
+ + P G P L+Q P AD L L + +L LSP P S +
Sbjct: 435 EEEIEPMEGPAPPVLIQLSPPNTDADTREL-----LVSQHTVQLVGGLSPLSSP---SDT 486
Query: 1139 KITEPLREGPEEE--PLAEREVKAEVEDMDEGPTELPPLESPLPLPAAE 1185
K P + PEE PL ++ A+ + E PLPL E
Sbjct: 487 KAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQPLPLKIEE 535
Score = 34.3 bits (77), Expect = 1.9
Identities = 36/146 (24%), Positives = 59/146 (40%), Gaps = 18/146 (12%)
Query: 1775 PKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEE 1834
P+ +R + R + + QP E E + + S + D++ +EEE+EEE
Sbjct: 221 PRKGERRSSRVRQARAAKLSEGSQP----AEEEEDQETPSRNLRVRADRNLKTEEEEEEE 276
Query: 1835 ELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQ 1894
E EEED+ G G + R +L F P V P ++ +
Sbjct: 277 EEEEEDDEEEEGDDEGQKSREAP---------ILKEFKEEGEEIPRVKPE---EMMDERP 324
Query: 1895 KARKKEERQSLLGTEFEYTDSESEVK 1920
K R +E Q +L +T S+ E +
Sbjct: 325 KTRSQE--QEVLERGGRFTRSQEEAR 348
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 85.1 bits (209), Expect = 9e-16
Identities = 126/543 (23%), Positives = 198/543 (36%), Gaps = 99/543 (18%)
Query: 2298 PSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEV 2357
P AK+ +K S E + P AK K G AA E + ++E
Sbjct: 73 PVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEE- 131
Query: 2358 PSTPLALEPSSTPGSKKSPPEP-VDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELP 2416
+ + KK P + V +AKA KA P + S + +S P P + P
Sbjct: 132 -----SSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEP-PKNQKP 185
Query: 2417 APATSLAPAPLITMPATRPKPKKARAA-------------------------EESGAKGP 2451
P+ T+ PK ARAA EE A P
Sbjct: 186 KIT------PVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239
Query: 2452 RRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSS 2511
++ + +++ K + T+P K + ED + +E K + P +
Sbjct: 240 KKTVPKKQVVAKAPVKAATTPTRKSSSS-----EDSSSDEEEEQKKPMK-NKPGPYSSVP 293
Query: 2512 EPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSS- 2570
P AP PK + L +P P E +S + + E D + E E + + S +
Sbjct: 294 PPSAPPPKKS---LGTQP-PKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT 349
Query: 2571 -----------SSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSS-- 2617
SSS SS +E +E K + + S A PA++
Sbjct: 350 TKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQP 409
Query: 2618 -----------SSSSSSSSSSSSSSSSSS----SSSSSSSSSSSSSSSSSSSSSSSSSSS 2662
+ SSSS SSSS + +++ +++ ++ S + + S S
Sbjct: 410 VGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDS 469
Query: 2663 SSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTK-ATKQAGKARPSAHSPG--- 2718
SS S SSSS +E+ + S + P AG A P+K A+ + GKA S S
Sbjct: 470 SSDSDSSSSEEEEEKTSKSAVKKKPQKVAG----GAAPSKPASAKKGKAESSNSSSSDDS 525
Query: 2719 --------KKTPAPQPQAPPPQPTQPLQPKAQAGAKS-----RPKKREGVHLPTTKELAK 2765
K +P+PQAP T L + AK+ KK+ V + + L K
Sbjct: 526 SEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKK 585
Query: 2766 RQR 2768
R++
Sbjct: 586 RKQ 588
Score = 76.6 bits (187), Expect = 3e-13
Identities = 100/453 (22%), Positives = 161/453 (35%), Gaps = 41/453 (9%)
Query: 2291 PSPALLVPSAKRRSRKTSKDTGEG--KDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATL 2348
P A S S ++S D E K +P AKA K + + D ++
Sbjct: 116 PGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSS 175
Query: 2349 EEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPA 2408
E+ P ++ P + P + K+PP+P K + A S + + +
Sbjct: 176 EDEPPKNQKPK----ITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSE 231
Query: 2409 PEPFAELPAPAT------SLAPAPLITMPATRP---------------KPKKARAAEESG 2447
E A P + AP T P + KP K + S
Sbjct: 232 EEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSS 291
Query: 2448 AKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEP--KSLLSLGSYP 2505
P P + L + + V + ++ E D + ++P K+++S +
Sbjct: 292 VPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTK 351
Query: 2506 P-----AAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESS 2560
P AA SS + + D + +P G T S P K+ A + A +
Sbjct: 352 PPPAKKAAESSSDSSDSDSSEDDEAPSKPA-GTTKNSSNKPAVTTKSPAVKPAAAPKQPV 410
Query: 2561 SSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAAS--SRAASPASSSSS 2618
+ + SSSS + EEE K +A S ++ A S SS
Sbjct: 411 GGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSS 470
Query: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSS 2678
S S SSSS +S S+ + ++ S +S+ + SS+SSSS + E+
Sbjct: 471 SDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEE 530
Query: 2679 CSSDDEAAPAPTA----GPSAQAALPTKATKQA 2707
+ +P P A G SA A KA K +
Sbjct: 531 EKLKGKGSPRPQAPKANGTSALTAQNGKAAKNS 563
Score = 68.9 bits (167), Expect = 7e-11
Identities = 120/493 (24%), Positives = 172/493 (34%), Gaps = 110/493 (22%)
Query: 2338 AKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPS 2397
AKA G AT ++ N + + L+ + P K PV K+AK KA + + S
Sbjct: 35 AKATG---ATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKK-KASSSDSEDS 90
Query: 2398 PAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEE 2457
P P A +PA L P K A A ES + ++
Sbjct: 91 SEEEEEVQGP-PAKKAAVPAKRVGLPPG------------KAAAKASESSSSEESSDDDD 137
Query: 2458 AELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEP-KAP 2516
E K + P++K AK PK S S ++ EP K
Sbjct: 138 EEDQKKQPVQKGVKPQAKAAKAP--------------PKKAKSSDSDSDSSSEDEPPKNQ 183
Query: 2517 WPKATDGDL-AQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSS------ 2569
PK T + AQ P PK A +G S SSSSSSS SS
Sbjct: 184 KPKITPVTVKAQTKAP---------PKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEK 234
Query: 2570 -----------------------------SSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600
SSSS SS E E +++ KN G
Sbjct: 235 AAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYS---- 290
Query: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--SSS 2658
S A P S + + SS SS S SSS + + S +
Sbjct: 291 --SVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKA 348
Query: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPG 2718
++ + ++ S++D S SS+D+ AP +K AG + S++ P
Sbjct: 349 TTKPPPAKKAAESSSDSSDSDSSEDDEAP----------------SKPAGTTKNSSNKPA 392
Query: 2719 --KKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSV---E 2773
K+PA +P A P QP Q A S + E ++ E K +++ + +
Sbjct: 393 VTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEES----SSSEEEKTKKMVATTKPK 448
Query: 2774 NRPKIAAFLPARQ 2786
K A LPA+Q
Sbjct: 449 ATAKAALSLPAKQ 461
Score = 62.0 bits (149), Expect = 8e-09
Identities = 98/472 (20%), Positives = 164/472 (34%), Gaps = 66/472 (13%)
Query: 2278 RLLPPDYKIQC-AEPSPALLVP----------SAKRRSRKTSKDTGEGKDGGTAGSEEPG 2326
++ P K Q A P PA P S+ S +S D+ E K T P
Sbjct: 186 KITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPK 245
Query: 2327 AKARGRG---------RKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPP 2377
+ + RK S+ E+ P P ++ P S P KKS
Sbjct: 246 KQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLG 305
Query: 2378 EPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPE--PFAELPAPATSLAPAPLITMPATRP 2435
K+A K +P + + +S + P + + AT+ P PA +
Sbjct: 306 TQPPKKA-VEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPP------PAKKA 358
Query: 2436 KPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEP 2495
+ +++ ++ P + A ++ + KS K A ++ G G
Sbjct: 359 AESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLT 418
Query: 2496 KSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAE 2555
+ S S ++ S E K AT PK+ KA +
Sbjct: 419 RKADSSSSEEESSSSEEEKTKKMVATT-----------------KPKATAKAALSLPAKQ 461
Query: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615
+ S SSS S SSSS + ++ + GG AA S+ PAS+
Sbjct: 462 APQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG---------AAPSK---PASA 509
Query: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
+ SS+SSSS SS S + ++ +S+ ++ + ++ +S +E
Sbjct: 510 KKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEE 569
Query: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQ 2727
+AA + S + +A K+A P A +TP P+
Sbjct: 570 KK------KAAVVVSKSGSLKKRKQNEAAKEA--ETPQAKKIKLQTPNTFPK 613
Score = 60.5 bits (145), Expect = 2e-08
Identities = 159/729 (21%), Positives = 268/729 (36%), Gaps = 150/729 (20%)
Query: 1468 AMKSSLEDMDALELDFRMRLAEVQRQYKEKQRELVKLQRRR----DSEDRREEPHRSLAR 1523
A SSL D+ F ++ A+V + + + K +++ DSED EE
Sbjct: 45 ANASSLLDI----YSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEV--- 97
Query: 1524 RGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLSSKSLLTSDDYELGAGIRKRHKGSEEEH 1583
+GP + A PP GK+ + + SS + DD E + KG + +
Sbjct: 98 QGPPAKKAAVPAKRVGLPP---GKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQA 154
Query: 1584 DALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLK 1643
A KA + + ++ S +S+ E ++ K +T + + K
Sbjct: 155 KA----AKAPPKKAKSSDSDSDS-------------SSEDEPPKNQKPKITPVTVKAQTK 197
Query: 1644 SPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTR 1703
+P K + +A + + A + S SS + + ++AA T
Sbjct: 198 APPKPARAA------------------PKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239
Query: 1704 KMEVGFK---ARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSL 1760
K V K A+ K+A +P + SS S ++ S+E+EE K GP SS PS
Sbjct: 240 KKTVPKKQVVAKAPVKAATTP--TRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPS- 296
Query: 1761 LCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATS----------RKQPFCLLLREAEAR 1810
A K + G + K+ + + ++ +S +K P ++ +A +
Sbjct: 297 -----APPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTK 351
Query: 1811 ----SSFSDSSEESFDQDESSEEEDEEEELEEEDEAS----------------------G 1844
++SS +S D D S ++E + +S G
Sbjct: 352 PPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVG 411
Query: 1845 GGYRLGARERALSPGLEESGLG---LLARFAASALPSPTVGPSLSVVQLEAKQKAR-KKE 1900
GG +L R+ S EES + A+ P T +LS+ +A Q +R
Sbjct: 412 GGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSS 471
Query: 1901 ERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDK 1960
+ S E E S+S VK + + AG P K P+ A SS D
Sbjct: 472 DSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSK------PASAKKGKAESSNSSSSDDS 525
Query: 1961 AKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPA 2020
++ + KL+G P +A P+A+ T + + AA +
Sbjct: 526 SE------EEEEKLKGKGSPRPQA-PKANGTSALTAQNGK--------AAKNSEEEEEEK 570
Query: 2021 TKTSRC-AKGGPLSPRKDAGRAKDRKDPRKKK----------KGKEAGPGAGLPPPRAPA 2069
K + +K G L RK AK+ + P+ KK K K+ A P R
Sbjct: 571 KKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVRE 630
Query: 2070 LPSEARAPHASSLTAAKR----------------SKAKAKGKEVKKENRG--KGGAVSKL 2111
E + A + AKR +K K+ E K+ RG +GG++S
Sbjct: 631 EEIEVDSRVADNSFDAKRGAAGDWGERANQVLKFTKGKSFRHEKTKKKRGSYRGGSISVQ 690
Query: 2112 MESMAAEED 2120
+ S+ + +
Sbjct: 691 VNSIKFDSE 699
Score = 60.1 bits (144), Expect = 3e-08
Identities = 120/557 (21%), Positives = 198/557 (35%), Gaps = 75/557 (13%)
Query: 1625 QLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGL 1684
++A+K KA T+QD S D K++ R L + K +K +
Sbjct: 29 EVANKFAKATGATQQDANAS--SLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSD 86
Query: 1685 GLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKD 1744
S SS E + + +K V K G P + ASE SS ++D +++E+ K
Sbjct: 87 --SEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQ 144
Query: 1745 EW--------------PAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKP 1790
P + SS + S KN K PK+T + A P
Sbjct: 145 PVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQK----PKITPVTVKAQTKAPP 200
Query: 1791 KPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLG 1850
KPA + + + +A SS S SS SS +D EEE
Sbjct: 201 KPARAAPK-----IANGKAASSSSSSS-------SSSSSDDSEEE--------------- 233
Query: 1851 ARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEF 1910
+ A +P ++A+ A +PT S S E ++E+++ +
Sbjct: 234 --KAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSS----EDSSSDEEEEQKKPMKNKPG 287
Query: 1911 EYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRK 1970
Y+ + G PKK + + P ++ S +K K
Sbjct: 288 PYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSK 347
Query: 1971 ARKLRGPKEPGFEAGPEASDDDLW--TRRRSERIFLHDASAAAPAPVSTAPATKTSRCAK 2028
A P + E+ ++SD D S+ S+ PA + +PA K + K
Sbjct: 348 ATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPK 407
Query: 2029 ----GGP--LSPRKDAGRAKDRKDPRKKKKGKE----------AGPGAGLPPPRAPALPS 2072
GG L+ + D+ +++ +++K K+ A LP +AP
Sbjct: 408 QPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSR 467
Query: 2073 EARAPHASSLTAAKRSKAKAKGKEVKKENRGKGGAVSKLMESM--AAEEDFEPNQDSSFS 2130
++ + SS + + K + K + G A SK + AE + D S
Sbjct: 468 DSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSE 527
Query: 2131 EDEHLPRGGAVERPLTP 2147
E+E +G RP P
Sbjct: 528 EEEEKLKGKGSPRPQAP 544
Score = 45.8 bits (107), Expect = 6e-04
Identities = 62/298 (20%), Positives = 106/298 (35%), Gaps = 48/298 (16%)
Query: 1889 QLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTP 1948
+L+A KK ++++ + ++ E EV+ A + P K +G P AA
Sbjct: 67 KLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAV--PAKRVGLPPGKAAAKAS 124
Query: 1949 GARGPDPSSPD-----KAKLAVEKG----RKARKLRGPKEPGFEAGPEASDDDLWTRRRS 1999
+ + SS D + K V+KG KA K K ++ ++S +D + +
Sbjct: 125 ESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQK 184
Query: 2000 ERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPG 2059
+I A AP PA + A G S + + D ++K
Sbjct: 185 PKITPVTVKAQTKAPPK--PARAAPKIANGKAASSSSSSSSSSSSDDSEEEK-------A 235
Query: 2060 AGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKG-----KEVKKENRGKGGAVSKL--- 2111
A P P A+AP ++ T ++S + +E KK + K G S +
Sbjct: 236 AATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPP 295
Query: 2112 --------------------MESMAAEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAP 2149
+ + + ED DSS E++ P V + T P
Sbjct: 296 SAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPP 353
Score = 39.3 bits (90), Expect = 0.059
Identities = 87/426 (20%), Positives = 143/426 (33%), Gaps = 58/426 (13%)
Query: 2282 PDYKIQCAEPSPALLVPSAKRRSRKTSKDTGE--------GKDGGTAGSEEPGAKA--RG 2331
P ++ P A P+ K S + S E K G + P A +
Sbjct: 244 PKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKS 303
Query: 2332 RGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRA--KAPKA 2389
G +P KA + + +DE SS+ KK P + V +A K P A
Sbjct: 304 LGTQPPKKAVEKQQPVESSEDSSDE--------SDSSSEEEKKPPTKAVVSKATTKPPPA 355
Query: 2390 RPAPPQPS-------------PAPPAFTSCPAP-EPFAELPAPATSLAPAPLITMPATRP 2435
+ A S P+ PA T+ + +P +PA A AP P
Sbjct: 356 KKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAP--KQPVGGG 413
Query: 2436 KPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEP 2495
+ R A+ S ++ EE + + T PK+ AK AL L Q P
Sbjct: 414 QKLLTRKADSSSSEEESSSSEEEKTKKMV---ATTKPKAT-AKAALSLPAK------QAP 463
Query: 2496 KSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAE 2555
+ S ++ S E + K+ Q+ G +P K + + G
Sbjct: 464 QGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGA---------APSKPASAKKG-- 512
Query: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615
++ESS+SSSS SS G + + NG T +A +S
Sbjct: 513 KAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSAL-TAQNGKAAKNSEEEEEEKK 571
Query: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
++ S S S + ++ + + + + ++ +SS +E
Sbjct: 572 KAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREE 631
Query: 2676 DSSCSS 2681
+ S
Sbjct: 632 EIEVDS 637
Score = 33.5 bits (75), Expect = 3.2
Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 9/145 (6%)
Query: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666
S A+ + ++ ++ +++SS S S+ ++ + + +SSS S
Sbjct: 28 SEVANKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDS 87
Query: 2667 SSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQP 2726
SS +E + A PA G P KA +A ++ S S Q
Sbjct: 88 EDSSEEEEEVQGPPAKKAAVPAKRVG-----LPPGKAAAKASESSSSEESSDDDDEEDQK 142
Query: 2727 QAPPPQPTQPLQPKAQAGAKSRPKK 2751
+ P + +P Q KA AK+ PKK
Sbjct: 143 KQPVQKGVKP-QAKA---AKAPPKK 163
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 84.7 bits (208), Expect = 1e-15
Identities = 54/207 (26%), Positives = 108/207 (52%), Gaps = 2/207 (0%)
Query: 2543 SPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNG--DGGCGTGGR 2600
S + + G + SS++SSG+S++++S SS+ S G ++ G GT
Sbjct: 213 SESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATN 272
Query: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2660
+ S+ S S ++S SS+ SS ++++++S SS++SS ++++++S SS++SS +S++++
Sbjct: 273 SESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATN 332
Query: 2661 SSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKK 2720
S SS++SS +ST S ++ A+ A +G S ++ + AT S S
Sbjct: 333 SESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATT 392
Query: 2721 TPAPQPQAPPPQPTQPLQPKAQAGAKS 2747
+ + + T +GA +
Sbjct: 393 SESSTTSSGASTATNSESSTVSSGAST 419
Score = 82.0 bits (201), Expect = 8e-15
Identities = 50/169 (29%), Positives = 93/169 (55%), Gaps = 6/169 (3%)
Query: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615
ES ++SS ++ +++S SS++SSG+ T E G S SS A++ +S
Sbjct: 304 ESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNS 363
Query: 2616 SSSSSSSSSSSSSSSSSSSSSSSSS------SSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2669
SS++SS +S++++S SS+ SS +S SS++SS +S++++S SS+ SS +S++++S
Sbjct: 364 GSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNS 423
Query: 2670 SSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPG 2718
S+T + ++ + + +AG A T + S PG
Sbjct: 424 ESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPG 472
Score = 72.0 bits (175), Expect = 8e-12
Identities = 60/240 (25%), Positives = 114/240 (47%), Gaps = 38/240 (15%)
Query: 2520 ATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGS 2579
AT+ D + T +S + + A + + SS +S++ +S SS++SS + +
Sbjct: 150 ATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGAST 209
Query: 2580 ETEGEEEGDKNGDG------------GCGTGGRNCSAASSRAASPASSSSSSSSSSSSSS 2627
T E NG G G T + S+ S A A++S SS++SS + +
Sbjct: 210 ATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGT 269
Query: 2628 SSSSSSS-------------SSSSSSSSSSSSSSSSSSSS----------SSSSSSSSSS 2664
+++S SS SS+ SS ++++++S SS++S SS++SS +S+
Sbjct: 270 ATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAST 329
Query: 2665 SSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQ---AALPTKATKQAGKARPSAHSPGKKT 2721
+++S SSTT +S +++ E++ + +A ++ + T A + S S G T
Sbjct: 330 ATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGAST 389
Score = 32.7 bits (73), Expect = 5.5
Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 13/120 (10%)
Query: 2508 AGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSS--SS 2565
+GSS + AT+ + + T + + ++ GA + +S SS SS
Sbjct: 363 SGSSTTSSGTSTATNSESS-------TVSSGASTATTSESSTTSSGASTATNSESSTVSS 415
Query: 2566 GSS---SSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSS 2622
G+S +S SS++SSG+ T G G GT +S +AS A S + S
Sbjct: 416 GASTATNSESSTTSSGANT-ATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGGS 474
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 82.8 bits (203), Expect = 5e-15
Identities = 262/1273 (20%), Positives = 425/1273 (33%), Gaps = 220/1273 (17%)
Query: 1577 KGSEEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDK-ALS 1635
+ SEEE +A KA R + + +D S +K K K + + + A
Sbjct: 86 ESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATG 145
Query: 1636 LTKQDKL--KSPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSRE 1693
T + L KSP K ++ + + S P K A S + +
Sbjct: 146 KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSS 205
Query: 1694 GKHKRAAKTRKME-------VGFKARGQPKSAHSPF----ASEVSSYSYNTDSEEDEEFL 1742
+ + + E A+G P +P A V+S + EED E
Sbjct: 206 SSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESS 265
Query: 1743 KDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCL 1802
+E S + TP+ + AK A G +AP P+ + P
Sbjct: 266 SEE----SSDSEEETPAAKALLQAK----ASGKTSQVGAASAPAKESPRKGAAPAPPGKT 317
Query: 1803 LLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEE 1862
A+A++ + +S SSEE D EEE + + SG ++ RA S +E
Sbjct: 318 GPAVAKAQAGKREEDSQS-----SSEESDSEEEAPAQAKPSGKAPQV----RAASAPAKE 368
Query: 1863 SGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVR 1922
S R A+ P GP+ + VQ+ +++ + +S E + ++VK
Sbjct: 369 S-----PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 423
Query: 1923 KRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGF 1982
+SP G+G P +G P P K GP P
Sbjct: 424 GKSPQVKPASTMGMG----------PLGKGAGPVPPGKV--------------GPATPSA 459
Query: 1983 EAGPEASDDDLWTRRRSERIFLHDASAAAPAPVST----APATKTSRCAKGGPLSPRKDA 2038
+ G D + + S+ +A APA + A TS AKG P A
Sbjct: 460 QVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVA 519
Query: 2039 GRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAK------RSKAKA 2092
+ K K + +E+ A APA + A+A A + K + A A
Sbjct: 520 VQVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASA 577
Query: 2093 KGKEVK---KENRGKGGAVSKLMESMA-AEEDFEPNQDSSFSEDEHLPRGGAVERPLTPA 2148
K V+ + R G A S S A A P +DSS SE+
Sbjct: 578 KVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES--------------- 622
Query: 2149 PRSCIIDKDELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQL 2208
D +E K GL V + + V+ P V+G G
Sbjct: 623 ------DSEEEKTGLAVTVGQAKSVGKGLQVKAASVP------VKGSLG----------- 659
Query: 2209 LQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGD 2268
+ V P T P T++ A + ++D + E D +
Sbjct: 660 --QGTAPVLPGKTG--PTVTQVKA-------------------EKQEDSESSEEESDSEE 696
Query: 2269 TGRIPL--------SHIRLLPPDYKIQCAE---PSPALLVPSA---KRRSRKTSKDTGEG 2314
P + + P + A+ +P +V +A K+RS K
Sbjct: 697 AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN 756
Query: 2315 KDGGTAGSEEPGA-KARGRGRKPSAKAK---GDRAATLEEGNPTDEVPSTPLALEPSSTP 2370
T + P + + G+ +A+A+ + + + EE + ++E T ++PS
Sbjct: 757 PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKT 816
Query: 2371 GSKK---SPPEPVDKRAKAP----KARPAPPQPSPAPPAFTSCPAPEPFAELPAPATS-- 2421
+ +P + ++ AP K P+ Q + +S + E PA TS
Sbjct: 817 HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 876
Query: 2422 -LAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEA 2480
+ P + P P A A+ A PR+ + S S+ E
Sbjct: 877 VIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK--------ARASESTARSSSSESEDED 928
Query: 2481 LLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATD-------GDLAQEPGPGL 2533
++ A P ++ + P A PKA A+ D ++ GP
Sbjct: 929 VI-----PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPA- 982
Query: 2534 TFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDG 2593
T NP S QA + S + + SS D
Sbjct: 983 TQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGV-----------------DS 1025
Query: 2594 GCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2653
GT ++S A + ++ + SS S SS SSS S
Sbjct: 1026 AVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEG 1085
Query: 2654 SSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALP--TKATKQAGKAR 2711
+ S+ + + S + T E+++ S ++ AP+ + P T A QA KA
Sbjct: 1086 PQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKAT 1145
Query: 2712 PSAHS--------PGKKTPAPQPQAPPPQPTQPLQPKA---QAGAKSRPKK----REGVH 2756
P S K P + +A P Q L PK +A + + P+K ++G
Sbjct: 1146 PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAG 1205
Query: 2757 LPTTKELAKRQRL 2769
P LA + +
Sbjct: 1206 NPQASTLALQSNI 1218
Score = 70.5 bits (171), Expect = 2e-11
Identities = 267/1274 (20%), Positives = 421/1274 (33%), Gaps = 199/1274 (15%)
Query: 944 AEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPG--------------------LAAGPA 983
+E EE+GS AA K G+ +AG + A+ PA
Sbjct: 171 SETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPA 230
Query: 984 -GTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSK------------PPAYAYPATPSSH 1030
GT GK +P P +A VA+ + K + ED P A A +S
Sbjct: 231 KGTPGKGATPAPPGKAGAVAS-QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASG 289
Query: 1031 PTSPPPASPPPTPGITRKEEAPE-----NVVEKKDLELEKEAPSPFQALFSDIPPRYPFQ 1085
TS A+ P RK AP K ++E S + SD P Q
Sbjct: 290 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ 349
Query: 1086 ALPPHYGRPYPFLLQPTAAADADGLAPDVPL---PADGPERLALSPEDKPIRLSPSKITE 1142
A P P + G AP P PA ++ ED S S E
Sbjct: 350 AKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED-----SRSSSEE 404
Query: 1143 PLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLE 1202
+ E LA A+V+ + + P P S + + A P P G G
Sbjct: 405 ---SDSDREALAAMNA-AQVKPLGKSPQVKPA--STMGMGPLGKGAGPVPPGKVGPATPS 458
Query: 1203 AQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEEPV 1262
AQ S + E D +G P +P + + L +P AK P
Sbjct: 459 AQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP-----AKGPPQ 513
Query: 1263 EV-PVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTC 1321
+ PVAV V P + S E + + A + + P+L+ + T
Sbjct: 514 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK-PALKIPQTKACPKKTN 572
Query: 1322 FLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLEQ 1381
A + P A + A P G A + + ES E+
Sbjct: 573 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVA-----GGTQRPAEDSSSSEESDSEEE 627
Query: 1382 SFLHGITLLSEIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDPL 1441
+T+ +++ +G + A ++ L G+ + GP V +
Sbjct: 628 KTGLAVTV----------GQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 677
Query: 1442 KNLRLPRELKPNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQREL 1501
K E+ +SS E+ D+ E A+V+ K+ Q +
Sbjct: 678 K--------------------AEKQEDSESSEEESDSEEA--AASPAQVKTSVKKTQAKA 715
Query: 1502 VKLQRRRDS-EDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKS------GHSSGK 1554
R S + P + + + R +PS + PP + ++ G +S
Sbjct: 716 NPAAARAPSAKGTISAPGKVVTAAAQAKQR----SPSKVKPPVRNPQNSTVLARGPASVP 771
Query: 1555 LSSKSLLTSDDYELG----AGIRKRHKGSEEEHDAL---------------IGMGKARGR 1595
K++ T+ + G +G + SEEE + L + K R
Sbjct: 772 SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPR 831
Query: 1596 NQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSD---SA 1652
+ + K+ S E+ S + ++T +K P F D S
Sbjct: 832 KGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP 891
Query: 1653 GGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKAR 1712
G + T TP RKA A SS T+ + G +
Sbjct: 892 AGPAATPAQAQAASTP--------RKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
Query: 1713 GQPK-SAHSPFASEVS--SYSYNTDSEEDEEFLKDEWPA-----QGPSSSKLTPSLLCSM 1764
+AH A + S S + +S + K E PA + P+S LT + L +
Sbjct: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
Query: 1765 VAKNSKAAGGPKLTKRGLAAPRTLKPKPATSR-------------KQPFCLLLREAEARS 1811
K S+A T+ + PATS ++P +++A
Sbjct: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1063
Query: 1812 SFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGL-----G 1866
SD SE+S D SEE+ E + + + LG +EE+
Sbjct: 1064 ESSDDSEDSSDSSSGSEEDGEGPQ------GAKSAHTLGPTPSRTETLVEETAAESSEDD 1117
Query: 1867 LLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSP 1926
++A + +L S + P L+ +A + K + S+ T D + + + + +
Sbjct: 1118 VVA--PSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA 1175
Query: 1927 AGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGP 1986
AG+L PK G G+ S P + + +A + + L G P EA
Sbjct: 1176 AGMLSPKTG-GKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQV 1234
Query: 1987 EASDDDLWTR-RRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRK 2045
+AS + T ER + D T KG RK +G +
Sbjct: 1235 QASVVKVLTELLEQERKKVVD--------------TTKESSRKGWESRKRKLSGDQPAAR 1280
Query: 2046 DPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKENRGKG 2105
PR KKK K+ G G G EA + T +K + K KE +GKG
Sbjct: 1281 TPRSKKK-KKLGAGEG----------GEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKG 1329
Query: 2106 GAVSKLMESMAAEE 2119
S+ + EE
Sbjct: 1330 SLGSQGAKDEPEEE 1343
Score = 62.0 bits (149), Expect = 8e-09
Identities = 60/254 (23%), Positives = 113/254 (44%), Gaps = 20/254 (7%)
Query: 2545 DKAQAEQDGAEESESS----------SSSSSGSSSSSSSSSSSGSE--TEGEEEGDKNGD 2592
+KA+AE + A ++ +S ++ SG S S+ S+ + +E EEEG
Sbjct: 123 EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAF 182
Query: 2593 GGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2652
G G ++ +A S + +SSSS + +S ++S+ + + ++
Sbjct: 183 GAAAKPGM---VSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGAT 239
Query: 2653 SSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARP 2712
+ + + +S + + E+ S SS +E++ + P+A+A L KA+ + +
Sbjct: 240 PAPPGKAGAVASQTKAGK---PEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV-G 295
Query: 2713 SAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSV 2772
+A +P K++P PP T P KAQAG + + + +E A Q PS
Sbjct: 296 AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE-APAQAKPSG 354
Query: 2773 ENRPKIAAFLPARQ 2786
+ AA PA++
Sbjct: 355 KAPQVRAASAPAKE 368
Score = 60.1 bits (144), Expect = 3e-08
Identities = 75/330 (22%), Positives = 129/330 (39%), Gaps = 56/330 (16%)
Query: 2501 LGSYPPAAGSSEPKAPWPKA-TDGDLAQEPGPGLTFEDSGNPKSPDKA-----------Q 2548
LG+ P++ + KA KA G+ P G T + + KSP K+ +
Sbjct: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172
Query: 2549 AEQDGAEESESSSS-----SSSGSSSSSSSSSSSGSETEGEEEGDKN------------G 2591
E++G+ + +++ S+ + SSS +SSS ET+ E + + G
Sbjct: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKG 232
Query: 2592 DGGCGT-----GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
G G G A+ ++A P S SSS SS S + ++ + + +S +S
Sbjct: 233 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 292
Query: 2647 SSSSSSSSSSSSSSSSSSSS----------SSSSSTTDEDSSCSSD--DEAAPAPTAGPS 2694
++S+ + S ++ + + + +EDS SS+ D AP
Sbjct: 293 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP----- 347
Query: 2695 AQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREG 2754
AQA KA + + P+ SP +K AP PP+ T P + Q G + +
Sbjct: 348 AQAKPSGKAPQVRAASAPAKESP-RKGAAP----APPRKTGPAAAQVQVGKQEEDSRSSS 402
Query: 2755 VHLPTTKELAKRQRLPSVENRPKIAAFLPA 2784
+ +E V+ K PA
Sbjct: 403 EESDSDREALAAMNAAQVKPLGKSPQVKPA 432
Score = 55.1 bits (131), Expect = 1e-06
Identities = 158/819 (19%), Positives = 259/819 (31%), Gaps = 135/819 (16%)
Query: 292 GLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGP-PAPPA 350
G P +E+ + ++ + A+ L + + + + P +P KG PAPP
Sbjct: 256 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
Query: 351 ATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVL 410
T V + E + S E + P A Q R A A +E+ R G
Sbjct: 316 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA 375
Query: 411 QAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEA 470
APP P + ++ RS +D + A A+ K L K
Sbjct: 376 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ-------VKPLGK-SP 427
Query: 471 DPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQH 530
+P GP G A + PG+ P P ++G + +
Sbjct: 428 QVKPASTMGMGPLGKGAGP------VPPGKVGPATPSA-----QVGKWEEDSESSSEESS 476
Query: 531 HHSRAEEEAAVVAASSSK-------KAYLDPGAVLPRSAATCG------RPVADMHSAAH 577
S E AV A K P P+ A +P+ + S+
Sbjct: 477 DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 536
Query: 578 GSGEASAMQSLIKYSGSFARDAVAV-RPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQAR 636
S A + ++ + + A+ A+ + + C KK+ + P T A A
Sbjct: 537 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 596
Query: 637 LPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGG 696
P PA GG Q RP E S + E++ G+AV V + K G
Sbjct: 597 SPAGSSPAVAGGTQ------RP-------AEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 643
Query: 697 -----------SGRLGPG---LVDQERSLSLSNVKGHGRADEDCVDDRARHREERLLGAR 742
G LG G ++ + +++ VK + D + ++ + E A+
Sbjct: 644 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 703
Query: 743 LDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATH 802
+ +K A+ +P + + G A + P+
Sbjct: 704 VKTSVKK---------TQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS---KVK 751
Query: 803 PWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQ----SGQL 858
P + N+++ G PA P +G ++ +A Q P+ S +
Sbjct: 752 PPVRNPQNSTVLARG---------------PASVPSVGKAVATAAQAQTGPEEDSGSSEE 796
Query: 859 VVIPSDHLPHFAELMERATVPPLWPALYPPGRSPLHHAQQLQLFSQQHFLRQQEFLYLQQ 918
+ A++ + AL P SP +
Sbjct: 797 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP-------------------------R 831
Query: 919 QAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGL 978
+ A ++ + K + + EE S G A P L+ P
Sbjct: 832 KGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD-GEAPAAVTSAQVIKPPLIFVDPNRS 890
Query: 979 AAGPAGT--YGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYP-------ATPSS 1029
AGPA T +A S P RAS A + + EDV P P++
Sbjct: 891 PAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 950
Query: 1030 HPTSPPPASPPPTPGIT--------RKEEAPENVVEKKD 1060
HP P AS +K+E P V KK+
Sbjct: 951 HPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKN 989
Score = 50.1 bits (118), Expect = 3e-05
Identities = 99/454 (21%), Positives = 160/454 (35%), Gaps = 92/454 (20%)
Query: 1706 EVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMV 1765
E+G K + + +A + VS ++S E+EE + E P + S+L + +
Sbjct: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADL 117
Query: 1766 AKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDE 1825
+ K + K G P PAT + L S
Sbjct: 118 PSSMKEKAKAETEKAGKTG--NSMPHPATGKTVANLL-----------------SGKSPR 158
Query: 1826 SSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSL 1885
S E L E E G GA A PG+ +G
Sbjct: 159 KSAEPSANTTLVSETEEEGSVPAFGA---AAKPGMVSAG--------------------- 194
Query: 1886 SVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAA 1945
+ + ++ S T+ E SE ++VR S P KG
Sbjct: 195 -------QADSSSEDTSSSSDETDVEVKASEKILQVRAAS-----APAKG---------- 232
Query: 1946 PTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLH 2005
TPG +G P+ P KA AV KA K P+E + E+SD + T +
Sbjct: 233 -TPG-KGATPAPPGKAG-AVASQTKAGK---PEEDSESSSEESSDSEEETPAAKALLQAK 286
Query: 2006 DASAAAPAPVSTAPATKTSR-------CAKGGPLSPRKDAG-RAKDRKDPRKKKKGKEAG 2057
+ + ++APA ++ R K GP + AG R +D + ++ +E
Sbjct: 287 ASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA 346
Query: 2058 PGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAA 2117
P P +AP + RA A + + ++ A A + K G + ++
Sbjct: 347 PAQAKPSGKAP----QVRAASAPAKESPRKGAAPAPPR--------KTGPAAAQVQVGKQ 394
Query: 2118 EEDFEPNQDSSFSEDEHLPRGGAVE-RPLTPAPR 2150
EED + + S S+ E L A + +PL +P+
Sbjct: 395 EEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 428
Score = 45.1 bits (105), Expect = 0.001
Identities = 79/374 (21%), Positives = 123/374 (32%), Gaps = 53/374 (14%)
Query: 2308 SKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDE------VPSTP 2361
S D E ++GSEE G +G + R TL E + PS
Sbjct: 1065 SSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQS 1124
Query: 2362 L-------ALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAE 2414
L L P+++ SK +P +D A P A P+ A
Sbjct: 1125 LLSGYMTPGLTPANSQASKATPK--LDSSPSVSSTLAAKDDPDGKQEA-----KPQQAAG 1177
Query: 2415 LPAPATSLAPAPLITMPATRPKPKKARAAEESGAK-----------GPRRPGEEAELLVK 2463
+ +P T A T P KPKK ++ G P EA++
Sbjct: 1178 MLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQAS 1237
Query: 2464 LDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDG 2523
+ + +T ++ K+ + ++ GW+ K LS G P A + P K
Sbjct: 1238 VV-KVLTELLEQERKKVVDTTKESSRKGWESRKRKLS-GDQPAA------RTPRSKKKKK 1289
Query: 2524 DLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEG 2583
A E G + + S KA+ ++ + E S GS G++ E
Sbjct: 1290 LGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ---------GAKDEP 1340
Query: 2584 EEEGDKNGDGGCGT-GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
EEE K G GT G + S S+ S + +S+ S S S
Sbjct: 1341 EEELQK----GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1396
Query: 2643 SSSSSSSSSSSSSS 2656
++ +
Sbjct: 1397 QKKKKKKKKTAEQT 1410
Score = 40.8 bits (94), Expect = 0.020
Identities = 70/309 (22%), Positives = 105/309 (33%), Gaps = 61/309 (19%)
Query: 339 PAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDAR 398
PAPP A + T AG E E + P+ +A + + SQ A
Sbjct: 240 PAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGK-TSQVGAAS 298
Query: 399 AREREAGRPGVLQAPPGSPRPL--DRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDP 456
A +E+ R G APPG P G RE++S S + +AP
Sbjct: 299 APAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP----------- 347
Query: 457 RAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELG 516
A +P +AP+ A A + + G P P TGP
Sbjct: 348 -------------AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGP---------- 384
Query: 517 NFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAA 576
AA Q+ V Q SR+ E + + A ++ V P + +P + M
Sbjct: 385 --AAAQVQV-GKQEEDSRSSSEES--DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 439
Query: 577 HGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAPTSAGAS-RAQA 635
G G A V PG G +P +G + + +S +S +
Sbjct: 440 LGKG------------------AGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG 481
Query: 636 RLPHSGGPA 644
+P + PA
Sbjct: 482 EVPTAVAPA 490
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 81.6 bits (200), Expect = 1e-14
Identities = 272/1287 (21%), Positives = 424/1287 (32%), Gaps = 247/1287 (19%)
Query: 1577 KGSEEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDK-ALS 1635
+ SEEE +A KA R + + +D S +K K K + + + A
Sbjct: 86 ESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATG 145
Query: 1636 LTKQDKL--KSPFKFSDSAGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSRE 1693
T + L KSP K ++ + + S P K A S + +
Sbjct: 146 KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSS 205
Query: 1694 GKHKRAAKTRKME-------VGFKARGQPKSAHSPF----ASEVSSYSYNTDSEEDEEFL 1742
+ + + E A+G P +P A V+S + EED E
Sbjct: 206 SSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESS 265
Query: 1743 KDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCL 1802
+E S + TP+ + AK A G +AP P+ + P
Sbjct: 266 SEE----SSDSEEETPAAKALLQAK----ASGKTSQVGAASAPAKESPRKGAAPAPPGKT 317
Query: 1803 LLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEE 1862
A+A++ + +S SSEE D EEE + + SG ++ RA S +E
Sbjct: 318 GPAVAKAQAGKREEDSQS-----SSEESDSEEEAPAQAKPSGKAPQV----RAASAPAKE 368
Query: 1863 SGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVR 1922
S R A+ P GP+ + VQ+ +++ + +S E + ++VK
Sbjct: 369 S-----PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 423
Query: 1923 KRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGF 1982
+SP G+G P +G P P K GP P
Sbjct: 424 GKSPQVKPASTMGMG----------PLGKGAGPVPPGKV--------------GPATPSA 459
Query: 1983 EAGPEASDDDLWTRRRSERIFLHDASAAAPAPVST----APATKTSRCAKGGPLSPRKDA 2038
+ G D + + S+ +A APA + A TS AKG P A
Sbjct: 460 QVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVA 519
Query: 2039 GRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAK------RSKAKA 2092
+ K K + +E+ A APA + A+A A + K + A A
Sbjct: 520 VQVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASA 577
Query: 2093 KGKEVK---KENRGKGGAVSKLMESMA-AEEDFEPNQDSSFSEDEHLPRGGAVERPLTPA 2148
K V+ + R G A S S A A P +DSS SE+
Sbjct: 578 KVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES--------------- 622
Query: 2149 PRSCIIDKDELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQL 2208
D +E K GL V + + V+ P V+G G
Sbjct: 623 ------DSEEEKTGLAVTVGQAKSVGKGLQVKAASVP------VKGSLG----------- 659
Query: 2209 LQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGD 2268
+ V P T P T++ A + ++D + E D +
Sbjct: 660 --QGTAPVLPGKTG--PTVTQVKA-------------------EKQEDSESSEEESDSEE 696
Query: 2269 TGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPG-- 2326
P ++ K Q A PSAK GT + PG
Sbjct: 697 AAASP---AQVKTSVKKTQAKANPAAARAPSAK----------------GTISA--PGKV 735
Query: 2327 --AKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRA 2384
A A+ + R PS R NP + ST LA P+S P K+ +
Sbjct: 736 VTAAAQAKQRSPSKVKPPVR-------NPQN---STVLARGPASVPSVGKAVATAAQAQT 785
Query: 2385 KAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAE 2444
+ + + S + + +P + +LAPA + P+K A
Sbjct: 786 GPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPA--------KESPRKGAAPT 837
Query: 2445 ESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEA------------LLLREDP--GAG 2490
G GP A K D G +S +S EA L+ DP
Sbjct: 838 PPGKTGP-----SAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA 892
Query: 2491 GWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPG-----PGLTFEDSGNPKSPD 2545
G + S P A +SE A + D P PG+ P +
Sbjct: 893 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHP 952
Query: 2546 K--AQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSE--------------TEGEEEGDK 2589
+ +A GA S+ SS S G ++ S + E
Sbjct: 953 RIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQP 1012
Query: 2590 NGDGGCGTGGRNCSAASSRAASPASSSSSSSSSS----------SSSSSSSSSSSSSSSS 2639
+ G + + + A SP S+S + ++ ++ + SS S S
Sbjct: 1013 PVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDS 1072
Query: 2640 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAAL 2699
S SSS S + S+ + + S + T E+++ S ++ AP+ +
Sbjct: 1073 SDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMT 1132
Query: 2700 P--TKATKQAGKARPSAHS--------PGKKTPAPQPQAPPPQPTQPLQPKA---QAGAK 2746
P T A QA KA P S K P + +A P Q L PK +A +
Sbjct: 1133 PGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASG 1192
Query: 2747 SRPKK----REGVHLPTTKELAKRQRL 2769
+ P+K ++G P LA + +
Sbjct: 1193 TTPQKSRKPKKGAGNPQASTLALQSNI 1219
Score = 71.6 bits (174), Expect = 1e-11
Identities = 266/1269 (20%), Positives = 417/1269 (32%), Gaps = 188/1269 (14%)
Query: 944 AEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPG--------------------LAAGPA 983
+E EE+GS AA K G+ +AG + A+ PA
Sbjct: 171 SETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPA 230
Query: 984 -GTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSK------------PPAYAYPATPSSH 1030
GT GK +P P +A VA+ + K + ED P A A +S
Sbjct: 231 KGTPGKGATPAPPGKAGAVAS-QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASG 289
Query: 1031 PTSPPPASPPPTPGITRKEEAPE-----NVVEKKDLELEKEAPSPFQALFSDIPPRYPFQ 1085
TS A+ P RK AP K ++E S + SD P Q
Sbjct: 290 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ 349
Query: 1086 ALPPHYGRPYPFLLQPTAAADADGLAPDVPL---PADGPERLALSPEDKPIRLSPSKITE 1142
A P P + G AP P PA ++ ED S S E
Sbjct: 350 AKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED-----SRSSSEE 404
Query: 1143 PLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLE 1202
+ E LA A+V+ + + P P S + + A P P G G
Sbjct: 405 ---SDSDREALAAMNA-AQVKPLGKSPQVKPA--STMGMGPLGKGAGPVPPGKVGPATPS 458
Query: 1203 AQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEEPV 1262
AQ S + E D +G P +P + + L +P AK P
Sbjct: 459 AQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP-----AKGPPQ 513
Query: 1263 EV-PVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTC 1321
+ PVAV V P + S E + + A + + P+L+ + T
Sbjct: 514 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK-PALKIPQTKACPKKTN 572
Query: 1322 FLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLEQ 1381
A + P A + A P G A + + ES E+
Sbjct: 573 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVA-----GGTQRPAEDSSSSEESDSEEE 627
Query: 1382 SFLHGITLLSEIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDPL 1441
+T+ +++ +G + A ++ L G+ + GP V +
Sbjct: 628 KTGLAVTV----------GQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 677
Query: 1442 KNLRLPRELKPNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQREL 1501
K E+ +SS E+ D+ E A+V+ K+ Q +
Sbjct: 678 K--------------------AEKQEDSESSEEESDSEEA--AASPAQVKTSVKKTQAKA 715
Query: 1502 VKLQRRRDS-EDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKS------GHSSGK 1554
R S + P + + + R +PS + PP + ++ G +S
Sbjct: 716 NPAAARAPSAKGTISAPGKVVTAAAQAKQR----SPSKVKPPVRNPQNSTVLARGPASVP 771
Query: 1555 LSSKSLLTSDDYELG----AGIRKRHKGSEEEHDAL---------------IGMGKARGR 1595
K++ T+ + G +G + SEEE + L + K R
Sbjct: 772 SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPR 831
Query: 1596 NQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSD---SA 1652
+ + K+ S E+ S + ++T +K P F D S
Sbjct: 832 KGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP 891
Query: 1653 GGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKAR 1712
G + T TP RKA A SS T+ + G +
Sbjct: 892 AGPAATPAQAQAASTP--------RKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
Query: 1713 GQPK-SAHSPFASEVS--SYSYNTDSEEDEEFLKDEWPA-----QGPSSSKLTPSLLCSM 1764
+AH A + S S + +S + K E PA + P+S LT + L +
Sbjct: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
Query: 1765 VAKNSKAAGGPKLTKRGLAAPRTLKPKPATSR-------------KQPFCLLLREAEARS 1811
K S+A T+ + PATS ++P +++A
Sbjct: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1063
Query: 1812 SFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARF 1871
SD SE+S D SEE+ E + + G E S ++A
Sbjct: 1064 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVA-- 1121
Query: 1872 AASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLR 1931
+ +L S + P L+ +A + K + S+ T D + + + + + AG+L
Sbjct: 1122 PSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLS 1181
Query: 1932 PKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDD 1991
PK G G+ S P + + +A + + L G P EA +AS
Sbjct: 1182 PKTG-GKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1240
Query: 1992 DLWTR-RRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKK 2050
+ T ER + D T KG RK +G + PR K
Sbjct: 1241 KVLTELLEQERKKVVD--------------TTKESSRKGWESRKRKLSGDQPAARTPRSK 1286
Query: 2051 KKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKENRGKGGAVSK 2110
KK K+ G G G EA + T +K + K KE +GKG S+
Sbjct: 1287 KK-KKLGAGEG----------GEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1335
Query: 2111 LMESMAAEE 2119
+ EE
Sbjct: 1336 GAKDEPEEE 1344
Score = 62.0 bits (149), Expect = 8e-09
Identities = 60/254 (23%), Positives = 113/254 (44%), Gaps = 20/254 (7%)
Query: 2545 DKAQAEQDGAEESESS----------SSSSSGSSSSSSSSSSSGSE--TEGEEEGDKNGD 2592
+KA+AE + A ++ +S ++ SG S S+ S+ + +E EEEG
Sbjct: 123 EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAF 182
Query: 2593 GGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2652
G G ++ +A S + +SSSS + +S ++S+ + + ++
Sbjct: 183 GAAAKPGM---VSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGAT 239
Query: 2653 SSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARP 2712
+ + + +S + + E+ S SS +E++ + P+A+A L KA+ + +
Sbjct: 240 PAPPGKAGAVASQTKAGK---PEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV-G 295
Query: 2713 SAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSV 2772
+A +P K++P PP T P KAQAG + + + +E A Q PS
Sbjct: 296 AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE-APAQAKPSG 354
Query: 2773 ENRPKIAAFLPARQ 2786
+ AA PA++
Sbjct: 355 KAPQVRAASAPAKE 368
Score = 60.1 bits (144), Expect = 3e-08
Identities = 75/330 (22%), Positives = 129/330 (39%), Gaps = 56/330 (16%)
Query: 2501 LGSYPPAAGSSEPKAPWPKA-TDGDLAQEPGPGLTFEDSGNPKSPDKA-----------Q 2548
LG+ P++ + KA KA G+ P G T + + KSP K+ +
Sbjct: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172
Query: 2549 AEQDGAEESESSSS-----SSSGSSSSSSSSSSSGSETEGEEEGDKN------------G 2591
E++G+ + +++ S+ + SSS +SSS ET+ E + + G
Sbjct: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKG 232
Query: 2592 DGGCGT-----GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
G G G A+ ++A P S SSS SS S + ++ + + +S +S
Sbjct: 233 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 292
Query: 2647 SSSSSSSSSSSSSSSSSSSS----------SSSSSTTDEDSSCSSD--DEAAPAPTAGPS 2694
++S+ + S ++ + + + +EDS SS+ D AP
Sbjct: 293 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP----- 347
Query: 2695 AQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREG 2754
AQA KA + + P+ SP +K AP PP+ T P + Q G + +
Sbjct: 348 AQAKPSGKAPQVRAASAPAKESP-RKGAAP----APPRKTGPAAAQVQVGKQEEDSRSSS 402
Query: 2755 VHLPTTKELAKRQRLPSVENRPKIAAFLPA 2784
+ +E V+ K PA
Sbjct: 403 EESDSDREALAAMNAAQVKPLGKSPQVKPA 432
Score = 57.0 bits (136), Expect = 3e-07
Identities = 195/1043 (18%), Positives = 333/1043 (31%), Gaps = 166/1043 (15%)
Query: 292 GLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGP-PAPPA 350
G P +E+ + ++ + A+ L + + + + P +P KG PAPP
Sbjct: 256 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
Query: 351 ATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVL 410
T V + E + S E + P A Q R A A +E+ R G
Sbjct: 316 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA 375
Query: 411 QAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEA 470
APP P + ++ RS +D + A A+ K L K
Sbjct: 376 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ-------VKPLGK-SP 427
Query: 471 DPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQH 530
+P GP G A + PG+ P P ++G + +
Sbjct: 428 QVKPASTMGMGPLGKGAGP------VPPGKVGPATPSA-----QVGKWEEDSESSSEESS 476
Query: 531 HHSRAEEEAAVVAASSSK-------KAYLDPGAVLPRSAATCG------RPVADMHSAAH 577
S E AV A K P P+ A +P+ + S+
Sbjct: 477 DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 536
Query: 578 GSGEASAMQSLIKYSGSFARDAVAV-RPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQAR 636
S A + ++ + + A+ A+ + + C KK+ + P T A A
Sbjct: 537 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 596
Query: 637 LPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGG 696
P PA GG Q RP E S + E++ G+AV V + K G
Sbjct: 597 SPAGSSPAVAGGTQ------RP-------AEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 643
Query: 697 -----------SGRLGPG---LVDQERSLSLSNVKGHGRADEDCVDDRARHREERLLGAR 742
G LG G ++ + +++ VK + D + ++ + E A+
Sbjct: 644 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 703
Query: 743 LDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATH 802
+ +K A+ +P + + G A + P+
Sbjct: 704 VKTSVKK---------TQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS---KVK 751
Query: 803 PWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQ----SGQL 858
P + N+++ G PA P +G ++ +A Q P+ S +
Sbjct: 752 PPVRNPQNSTVLARG---------------PASVPSVGKAVATAAQAQTGPEEDSGSSEE 796
Query: 859 VVIPSDHLPHFAELMERATVPPLWPALYPPGRSPLHHAQQLQLFSQQHFLRQQEFLYLQQ 918
+ A++ + AL P SP +
Sbjct: 797 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP-------------------------R 831
Query: 919 QAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGL 978
+ A ++ + K + + EE S G A P L+ P
Sbjct: 832 KGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD-GEAPAAVTSAQVIKPPLIFVDPNRS 890
Query: 979 AAGPAGT--YGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYP-------ATPSS 1029
AGPA T +A S P RAS A + + EDV P P++
Sbjct: 891 PAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 950
Query: 1030 HPTSPPPASPPPTPGIT--------RKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPR 1081
HP P AS +K+E P V KK+ A P + +
Sbjct: 951 HPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKN-----PASLPLTQAALKVLAQ 1005
Query: 1082 YPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKIT 1141
+A PP QP++ D + LPA P+ ++ + +K+
Sbjct: 1006 KASEAQPP------VARTQPSSGVD----SAVGTLPATSPQSTSVQAK------GTNKLR 1049
Query: 1142 EPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLL 1201
+P ++ A + D E P +A + P+P+ L+
Sbjct: 1050 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSR--TETLV 1107
Query: 1202 EAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEEP 1261
E A ++ PS+ + G +P ++ A L + + + AK++P
Sbjct: 1108 EETAAESSEDDVVAPSQ--SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDP 1165
Query: 1262 VEVPVAVPVVEAVPEEGLAQVAP 1284
EA P++ ++P
Sbjct: 1166 DGKQ------EAKPQQAAGMLSP 1182
Score = 50.1 bits (118), Expect = 3e-05
Identities = 99/454 (21%), Positives = 160/454 (35%), Gaps = 92/454 (20%)
Query: 1706 EVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMV 1765
E+G K + + +A + VS ++S E+EE + E P + S+L + +
Sbjct: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADL 117
Query: 1766 AKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDE 1825
+ K + K G P PAT + L S
Sbjct: 118 PSSMKEKAKAETEKAGKTG--NSMPHPATGKTVANLL-----------------SGKSPR 158
Query: 1826 SSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSL 1885
S E L E E G GA A PG+ +G
Sbjct: 159 KSAEPSANTTLVSETEEEGSVPAFGA---AAKPGMVSAG--------------------- 194
Query: 1886 SVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAA 1945
+ + ++ S T+ E SE ++VR S P KG
Sbjct: 195 -------QADSSSEDTSSSSDETDVEVKASEKILQVRAAS-----APAKG---------- 232
Query: 1946 PTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLH 2005
TPG +G P+ P KA AV KA K P+E + E+SD + T +
Sbjct: 233 -TPG-KGATPAPPGKAG-AVASQTKAGK---PEEDSESSSEESSDSEEETPAAKALLQAK 286
Query: 2006 DASAAAPAPVSTAPATKTSR-------CAKGGPLSPRKDAG-RAKDRKDPRKKKKGKEAG 2057
+ + ++APA ++ R K GP + AG R +D + ++ +E
Sbjct: 287 ASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA 346
Query: 2058 PGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAA 2117
P P +AP + RA A + + ++ A A + K G + ++
Sbjct: 347 PAQAKPSGKAP----QVRAASAPAKESPRKGAAPAPPR--------KTGPAAAQVQVGKQ 394
Query: 2118 EEDFEPNQDSSFSEDEHLPRGGAVE-RPLTPAPR 2150
EED + + S S+ E L A + +PL +P+
Sbjct: 395 EEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 428
Score = 43.1 bits (100), Expect = 0.004
Identities = 79/375 (21%), Positives = 121/375 (32%), Gaps = 54/375 (14%)
Query: 2308 SKDTGEGKDGGTAGSEEPGAKARGR-------GRKPSAKAKGDRAATLEEGNPTDEVPST 2360
S D E ++GSEE G +G G PS E PS
Sbjct: 1065 SSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQ 1124
Query: 2361 PL-------ALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFA 2413
L L P+++ SK +P +D A P A P+ A
Sbjct: 1125 SLLSGYMTPGLTPANSQASKATPK--LDSSPSVSSTLAAKDDPDGKQEA-----KPQQAA 1177
Query: 2414 ELPAPATSLAPAPLITMPATRPKPKKARAAEESGAK-----------GPRRPGEEAELLV 2462
+ +P T A T P KPKK ++ G P EA++
Sbjct: 1178 GMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQA 1237
Query: 2463 KLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATD 2522
+ + +T ++ K+ + ++ GW+ K LS G P A + P K
Sbjct: 1238 SVV-KVLTELLEQERKKVVDTTKESSRKGWESRKRKLS-GDQPAA------RTPRSKKKK 1289
Query: 2523 GDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETE 2582
A E G + + S KA+ ++ + E S GS G++ E
Sbjct: 1290 KLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ---------GAKDE 1340
Query: 2583 GEEEGDKNGDGGCGT-GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641
EEE K G GT G + S S+ S + +S+ S S
Sbjct: 1341 PEEELQK----GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESP 1396
Query: 2642 SSSSSSSSSSSSSSS 2656
S ++ +
Sbjct: 1397 SQKKKKKKKKTAEQT 1411
Score = 40.8 bits (94), Expect = 0.020
Identities = 70/309 (22%), Positives = 105/309 (33%), Gaps = 61/309 (19%)
Query: 339 PAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDAR 398
PAPP A + T AG E E + P+ +A + + SQ A
Sbjct: 240 PAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGK-TSQVGAAS 298
Query: 399 AREREAGRPGVLQAPPGSPRPL--DRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDP 456
A +E+ R G APPG P G RE++S S + +AP
Sbjct: 299 APAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP----------- 347
Query: 457 RAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELG 516
A +P +AP+ A A + + G P P TGP
Sbjct: 348 -------------AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGP---------- 384
Query: 517 NFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAA 576
AA Q+ V Q SR+ E + + A ++ V P + +P + M
Sbjct: 385 --AAAQVQV-GKQEEDSRSSSEES--DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 439
Query: 577 HGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAPTSAGAS-RAQA 635
G G A V PG G +P +G + + +S +S +
Sbjct: 440 LGKG------------------AGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG 481
Query: 636 RLPHSGGPA 644
+P + PA
Sbjct: 482 EVPTAVAPA 490
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 81.6 bits (200), Expect = 1e-14
Identities = 236/1129 (20%), Positives = 380/1129 (33%), Gaps = 210/1129 (18%)
Query: 1711 ARGQPKSAHSPF----ASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVA 1766
A+G P +P A V+S + EED E +E S + TP+ + A
Sbjct: 307 AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE----SSDSEEETPAAKALLQA 362
Query: 1767 KNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDES 1826
K A G +AP P+ + P A+A++ + +S S
Sbjct: 363 K----ASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS-----S 413
Query: 1827 SEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLS 1886
SEE D EEE + + SG ++ RA S +ES R A+ P GP+ +
Sbjct: 414 SEESDSEEEAPAQAKPSGKAPQV----RAASAPAKES-----PRKGAAPAPPRKTGPAAA 464
Query: 1887 VVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAP 1946
VQ+ +++ + +S E + ++VK +SP G+G
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG--------- 515
Query: 1947 TPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHD 2006
P +G P P K GP P + G D + + S+
Sbjct: 516 -PLGKGAGPVPPGKV--------------GPATPSAQVGKWEEDSESSSEESSDSSDGEV 560
Query: 2007 ASAAAPAPVST----APATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGL 2062
+A APA + A TS AKG P A + K K + +E+ A
Sbjct: 561 PTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA-- 618
Query: 2063 PPPRAPALPSEARAPHASSLTAAK------RSKAKAKGKEVK---KENRGKGGAVSKLME 2113
APA + A+A A + K + A AK V+ + R G A S
Sbjct: 619 DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGS 678
Query: 2114 SMA-AEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAPRSCIIDKDELKDGLRVLIPMDDK 2172
S A A P +DSS SE+ D +E K GL V +
Sbjct: 679 SPAVAGGTQRPAEDSSSSEES---------------------DSEEEKTGLAVTVGQAKS 717
Query: 2173 LLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAA 2232
+ V+ P V+G G + V P T P T++ A
Sbjct: 718 VGKGLQVKAASVP------VKGSLG-------------QGTAPVLPGKTG--PTVTQVKA 756
Query: 2233 YWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPL--------SHIRLLPPDY 2284
+ ++D + E D + P + + P
Sbjct: 757 -------------------EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 797
Query: 2285 KIQCAE---PSPALLVPSA---KRRSRKTSKDTGEGKDGGTAGSEEPGA-KARGRGRKPS 2337
+ A+ +P +V +A K+RS K T + P + + G+ +
Sbjct: 798 RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 857
Query: 2338 AKAK---GDRAATLEEGNPTDEVPSTPLALEPSSTPGSKK---SPPEPVDKRAKAP---- 2387
A+A+ + + + EE + ++E T ++PS + +P + ++ AP
Sbjct: 858 AQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG 917
Query: 2388 KARPAPPQPSPAPPAFTSCPAPEPFAELPAPATS---LAPAPLITMPATRPKPKKARAAE 2444
K P+ Q + +S + E PA TS + P + P P A A+
Sbjct: 918 KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
Query: 2445 ESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSY 2504
A PR+ + S S+ E ++ A P ++ +
Sbjct: 978 AQAASTPRK--------ARASESTARSSSSESEDEDVI-----PATQCLTPGIRTNVVTM 1024
Query: 2505 PPAAGSSEPKAPWPKATD-------GDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEES 2557
P A PKA A+ D ++ GP T NP S QA +
Sbjct: 1025 PTAHPRIAPKASMAGASSSKESSRISDGKKQEGPA-TQVSKKNPASLPLTQAALKVLAQK 1083
Query: 2558 ESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSS 2617
S + + SS D GT ++S A +
Sbjct: 1084 ASEAQPPVARTQPSSGV-----------------DSAVGTLPATSPQSTSVQAKGTNKLR 1126
Query: 2618 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDS 2677
++ + SS S SS SSS S + S+ + + S + T E++
Sbjct: 1127 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEET 1186
Query: 2678 SCSSDDEAAPAPTAGPSAQAALP--TKATKQAGKARPSAHS--------PGKKTPAPQPQ 2727
+ S ++ AP+ + P T A QA KA P S K P + +
Sbjct: 1187 AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1246
Query: 2728 APPPQPTQPLQPKA---QAGAKSRPKK----REGVHLPTTKELAKRQRL 2769
A P Q L PK +A + + P+K ++G P LA + +
Sbjct: 1247 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNI 1295
Score = 75.1 bits (183), Expect = 1e-12
Identities = 269/1264 (21%), Positives = 424/1264 (33%), Gaps = 183/1264 (14%)
Query: 935 ERLKAQEHRAEMEEKGSKRGLEA-AGKAGLATAGPGLLPRKPPGLAAGPA-GTYGKAVSP 992
+R K E +E E+GS+ EA AG A +L + A+ PA GT GK +P
Sbjct: 261 KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRA---ASAPAKGTPGKGATP 317
Query: 993 PPSPRASPVAALKAKVIQKLEDVSK------------PPAYAYPATPSSHPTSPPPASPP 1040
P +A VA+ + K + ED P A A +S TS A+
Sbjct: 318 APPGKAGAVAS-QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASA 376
Query: 1041 PTPGITRKEEAPE-----NVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPY 1095
P RK AP K ++E S + SD P QA P
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436
Query: 1096 PFLLQPTAAADADGLAPDVPL---PADGPERLALSPEDKPIRLSPSKITEPLREGPEEEP 1152
P + G AP P PA ++ ED S S E + E
Sbjct: 437 RAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED-----SRSSSEE---SDSDREA 488
Query: 1153 LAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQS 1212
LA A+V+ + + P P S + + A P P G G AQ S
Sbjct: 489 LAAMNA-AQVKPLGKSPQVKPA--STMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDS 545
Query: 1213 CAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEEPVEV-PVAVPVV 1271
+ E D +G P +P + + L +P AK P + PVAV V
Sbjct: 546 ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP-----AKGPPQKAGPVAVQVK 600
Query: 1272 EAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQF 1331
P + S E + + A + + P+L+ + T A
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAK-PALKIPQTKACPKKTNTTASAKVAPV 659
Query: 1332 LPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLEQSFLHGITLLS 1391
+ P A + A P G A + + ES E+ +T+
Sbjct: 660 RVGTQAPRKAGTATSPAGSSPAVA-----GGTQRPAEDSSSSEESDSEEEKTGLAVTV-- 712
Query: 1392 EIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDPLKNLRLPRELK 1451
+++ +G + A ++ L G+ + GP V +K
Sbjct: 713 --------GQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK--------- 755
Query: 1452 PNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDS- 1510
E+ +SS E+ D+ E A+V+ K+ Q + R S
Sbjct: 756 -----------AEKQEDSESSEEESDSEEA--AASPAQVKTSVKKTQAKANPAAARAPSA 802
Query: 1511 EDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKS------GHSSGKLSSKSLLTSD 1564
+ P + + + R +PS + PP + ++ G +S K++ T+
Sbjct: 803 KGTISAPGKVVTAAAQAKQR----SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
Query: 1565 DYELG----AGIRKRHKGSEEEHDAL---------------IGMGKARGRNQTWDEHEAS 1605
+ G +G + SEEE + L + K R
Sbjct: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGK 918
Query: 1606 SDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSD---SAGGKSKTSGGC 1662
+ + K+ S E+ S + ++T +K P F D S G + T
Sbjct: 919 TGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQA 978
Query: 1663 GRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQPK-SAHSP 1721
TP RKA A SS T+ + G + +AH
Sbjct: 979 QAASTP--------RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPR 1030
Query: 1722 FASEVS--SYSYNTDSEEDEEFLKDEWPA-----QGPSSSKLTPSLLCSMVAKNSKAAGG 1774
A + S S + +S + K E PA + P+S LT + L + K S+A
Sbjct: 1031 IAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPP 1090
Query: 1775 PKLTKRGLAAPRTLKPKPATSR-------------KQPFCLLLREAEARSSFSDSSEESF 1821
T+ + PATS ++P +++A SD SE+S
Sbjct: 1091 VARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS 1150
Query: 1822 DQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGL-----GLLARFAASAL 1876
D SEE+ E + + + LG +EE+ ++A + +L
Sbjct: 1151 DSSSGSEEDGEGPQ------GAKSAHTLGPTPSRTETLVEETAAESSEDDVVA--PSQSL 1202
Query: 1877 PSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGL 1936
S + P L+ +A + K + S+ T D + + + + + AG+L PK G
Sbjct: 1203 LSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTG- 1261
Query: 1937 GEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTR 1996
G+ S P + + +A + + L G P EA +AS + T
Sbjct: 1262 GKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTE 1321
Query: 1997 -RRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKE 2055
ER + D T KG RK +G + PR KKK K+
Sbjct: 1322 LLEQERKKVVD--------------TTKESSRKGWESRKRKLSGDQPAARTPRSKKK-KK 1366
Query: 2056 AGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKENRGKGGAVSKLMESM 2115
G G G EA + T +K + K KE +GKG S+ +
Sbjct: 1367 LGAGEG----------GEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDE 1416
Query: 2116 AAEE 2119
EE
Sbjct: 1417 PEEE 1420
Score = 73.2 bits (178), Expect = 4e-12
Identities = 111/497 (22%), Positives = 175/497 (35%), Gaps = 72/497 (14%)
Query: 2298 PSAKRRSRKTSKDTGEGKDG---GTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPT 2354
P+ + S ++K++ K G G P K AK + + + EEG+ +
Sbjct: 220 PAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSES 279
Query: 2355 DEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKAR--------PAPPQPSPAPPAFTSC 2406
+E P+ T K+ + + RA + A+ PAPP + A + T
Sbjct: 280 EEEA-------PAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA 332
Query: 2407 PAPEPFAELPAPATS-----LAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELL 2461
PE +E + +S A + K + AA + PR+ A
Sbjct: 333 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP-- 390
Query: 2462 VKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKAT 2521
G T P KA+ RE+ +E S PA KAP +A
Sbjct: 391 -----PGKTGPAVAKAQAGK--REEDSQSSSEESDS----EEEAPAQAKPSGKAPQVRAA 439
Query: 2522 DGDLAQEPGPGLTFEDSGNPKSPDKAQAE-QDGAEESESSSSSSSGSSSSSSSSSSSGSE 2580
+ P G P+ A A+ Q G +E +S SSS S + ++ + ++
Sbjct: 440 SAPAKESPRKGAA---PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496
Query: 2581 TE--GEEEGDKNGDG-GCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSS 2637
+ G+ K G G G+ PA+ S+ S SSS SS SS
Sbjct: 497 VKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS 556
Query: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------------SSSTTDEDSSC 2679
++ + + S + + +SS + +S + E+SS
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 616
Query: 2680 SSDDEAAPAPTAGPSAQAALPTKATKQAGK-------ARPSAHSPGKKTPAPQPQAPPPQ 2732
S+D E APA A+ AL TK K A+ + G + P A P
Sbjct: 617 SADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA 676
Query: 2733 PTQPLQPKAQAGAKSRP 2749
+ P A AG RP
Sbjct: 677 GSSP----AVAGGTQRP 689
Score = 65.1 bits (157), Expect = 1e-09
Identities = 94/379 (24%), Positives = 148/379 (39%), Gaps = 40/379 (10%)
Query: 2432 ATRPKPKKARAAEESGAKG-PRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAG 2490
+T ++ AE AK PR + +L G P S K K A E G
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVL------GADLPSSMKEK-AKAETEKAGKT 135
Query: 2491 GWQEP-----KSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPD 2545
G P K++ +L S S+EP A ++ +E G F + P
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE---TEEEGSVPAFGAAAKPGMVS 192
Query: 2546 KAQAEQDGAEESESSSSSS-----SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600
QA+ + S SS + S + +SS S E+ + G G T
Sbjct: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
Query: 2601 NCSAA--SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS-------SSSSSSSSSSS 2651
A + RA P S SS S S + + + S +S ++S+ + +
Sbjct: 253 KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312
Query: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKA---TKQAG 2708
++ + + + +S + + E+ S SS +E++ + P+A+A L KA T Q G
Sbjct: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG 372
Query: 2709 KAR-PSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQ 2767
A P+ SP +K AP PP T P KAQAG + + + +E A Q
Sbjct: 373 AASAPAKESP-RKGAAP----APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE-APAQ 426
Query: 2768 RLPSVENRPKIAAFLPARQ 2786
PS + AA PA++
Sbjct: 427 AKPSGKAPQVRAASAPAKE 445
Score = 61.2 bits (147), Expect = 1e-08
Identities = 108/480 (22%), Positives = 182/480 (37%), Gaps = 67/480 (13%)
Query: 1706 EVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMV 1765
E+G K + + +A + VS ++S E+EE + E P + S+L + +
Sbjct: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADL 117
Query: 1766 AKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLR------EAEARSSFSDSSEE 1819
+ K + K G P PAT + L + E A ++ +EE
Sbjct: 118 PSSMKEKAKAETEKAGKTG--NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
Query: 1820 ----------------SFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEES 1863
S Q +SS E+ +E + G A+ +A S +ES
Sbjct: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSS--SDETDVEGKPSVKPAQVKASSVSTKES 233
Query: 1864 GLGLLARFAASALPSP----TVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEV 1919
A A P+P V P + L ++A+K EE +E SESE
Sbjct: 234 P-------ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEE-----SESSEEGSESEE 281
Query: 1920 KVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKE 1979
+ + + + +K L S A +G P+ P KA AV KA K P+E
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG-AVASQTKAGK---PEE 337
Query: 1980 PGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSR-------CAKGGPL 2032
+ E+SD + T + + + ++APA ++ R K GP
Sbjct: 338 DSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPA 397
Query: 2033 SPRKDAG-RAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAK 2091
+ AG R +D + ++ +E P P +AP + RA A + + ++ A
Sbjct: 398 VAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP----QVRAASAPAKESPRKGAAP 453
Query: 2092 AKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVE-RPLTPAPR 2150
A + K G + ++ EED + + S S+ E L A + +PL +P+
Sbjct: 454 APPR--------KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 505
Score = 60.5 bits (145), Expect = 2e-08
Identities = 101/474 (21%), Positives = 167/474 (35%), Gaps = 63/474 (13%)
Query: 2354 TDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFA 2413
T E+ A E ++ K +P+ + + A + + A P S + A
Sbjct: 56 TSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGA 115
Query: 2414 ELPAPATSLAPAPLITMPAT---RPKPKKARA-AEESGAKGPRR---PGEEAELLVKLDH 2466
+LP+ A A T P P + A K PR+ P L+ + +
Sbjct: 116 DLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
Query: 2467 EG-------VTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPA----AGSSEPKA 2515
EG P A +A ED + + + S PA + S ++
Sbjct: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSS--DETDVEGKPSVKPAQVKASSVSTKES 233
Query: 2516 PWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSS 2575
P KA P PG + + K A++ E ES SS GS S + +
Sbjct: 234 PARKAA-------PAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE-GSESEEEAPA 285
Query: 2576 SSGSETEGEEE--------GDKNGDGGCGT-----GGRNCSAASSRAASPASSSSSSSSS 2622
+ S+ + E+ G G G G A+ ++A P S SSS
Sbjct: 286 GTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE 345
Query: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----------SSSSST 2672
SS S + ++ + + +S +S ++S+ + S ++ + + +
Sbjct: 346 SSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK 405
Query: 2673 TDEDSSCSSD--DEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPP 2730
+EDS SS+ D AP AQA KA + + P+ SP +K AP P
Sbjct: 406 REEDSQSSSEESDSEEEAP-----AQAKPSGKAPQVRAASAPAKESP-RKGAAP----AP 455
Query: 2731 PQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPA 2784
P+ T P + Q G + + + +E V+ K PA
Sbjct: 456 PRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 509
Score = 60.1 bits (144), Expect = 3e-08
Identities = 184/942 (19%), Positives = 299/942 (31%), Gaps = 153/942 (16%)
Query: 181 PSARTPGGGHSSGAPAKGSSSRDGPAKERAG------RGGEPPPLFGKKDPRARGEEASG 234
PS + SS + + + + PA + G +GG PP K P EE+
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPE---EESES 272
Query: 235 PRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDV--- 291
+ +EA A R + +E++ A S G AG V
Sbjct: 273 SEEGSESEEEAPAGTRSQ---VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 329
Query: 292 ---GLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGP-PA 347
G P +E+ + ++ + A+ L + + + + P +P KG PA
Sbjct: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 389
Query: 348 PPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRP 407
PP T V + E + S E + P A Q R A A +E+ R
Sbjct: 390 PPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK 449
Query: 408 GVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLK 467
G APP P + ++ RS +D + A A+ K L K
Sbjct: 450 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ-------VKPLGK 502
Query: 468 PEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLA 527
+P GP G A + PG+ P P ++G + +
Sbjct: 503 -SPQVKPASTMGMGPLGKGAGP------VPPGKVGPATPSA-----QVGKWEEDSESSSE 550
Query: 528 AQHHHSRAEEEAAVVAASSSK-------KAYLDPGAVLPRSAATCG------RPVADMHS 574
S E AV A K P P+ A +P+ + S
Sbjct: 551 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES 610
Query: 575 AAHGSGEASAMQSLIKYSGSFARDAVAV-RPGGCGKKSPFGGLGTMKPEPAPTSAGASRA 633
+ S A + ++ + + A+ A+ + + C KK+ + P T A
Sbjct: 611 SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAG 670
Query: 634 QARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKD 693
A P PA GG Q RP E S + E++ G+AV V + K
Sbjct: 671 TATSPAGSSPAVAGGTQ------RP-------AEDSSSSEESDSEEEKTGLAVTVGQAKS 717
Query: 694 SGG-----------SGRLGPG---LVDQERSLSLSNVKGHGRADEDCVDDRARHREERLL 739
G G LG G ++ + +++ VK + D + ++ + E
Sbjct: 718 VGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAAS 777
Query: 740 GARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHL 799
A++ +K A+ +P + + G A + P+
Sbjct: 778 PAQVKTSVKK---------TQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS--- 825
Query: 800 ATHPWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQ----S 855
P + N+++ G PA P +G ++ +A Q P+ S
Sbjct: 826 KVKPPVRNPQNSTVLARG---------------PASVPSVGKAVATAAQAQTGPEEDSGS 870
Query: 856 GQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSPLHHAQQLQLFSQQHFLRQQEFLY 915
+ + A++ + AL P SP
Sbjct: 871 SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP----------------------- 907
Query: 916 LQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKP 975
++ A ++ + K + + EE S G A P L+ P
Sbjct: 908 --RKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD-GEAPAAVTSAQVIKPPLIFVDP 964
Query: 976 PGLAAGPAGT--YGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYP-------AT 1026
AGPA T +A S P RAS A + + EDV P
Sbjct: 965 NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM 1024
Query: 1027 PSSHPTSPPPASPPPTPGIT--------RKEEAPENVVEKKD 1060
P++HP P AS +K+E P V KK+
Sbjct: 1025 PTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKN 1066
Score = 57.8 bits (138), Expect = 2e-07
Identities = 114/534 (21%), Positives = 182/534 (34%), Gaps = 84/534 (15%)
Query: 2291 PSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSE---EPGAKARGRGRKPSAKAKGDRAAT 2347
P PA A S K+ + + E T SE E A G KP + G ++
Sbjct: 140 PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSS 199
Query: 2348 LEE-GNPTDEV-----PSTPLALEPSSTPGSKKSP-----PEP-----VDKRAKAPKARP 2391
E+ + +DE PS A +S+ +K+SP P P V + K P
Sbjct: 200 SEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP 259
Query: 2392 APPQPSPAPPAFTSCPAPEPFAELPAPATS------------LAPAPLITMP---ATRPK 2436
A P + +S E E PA S A AP P AT
Sbjct: 260 AKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAP 319
Query: 2437 PKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPK 2496
P KA A G +P E++E E S + A +ALL + G
Sbjct: 320 PGKAGAVASQTKAG--KPEEDSE---SSSEESSDSEEETPAAKALLQAKASGK------T 368
Query: 2497 SLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEE 2556
S + S P + AP P + GP + +G + ++ +E+ +EE
Sbjct: 369 SQVGAASAPAKESPRKGAAPAPPG-------KTGPAVAKAQAGKREEDSQSSSEESDSEE 421
Query: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616
+ + SG + ++S+ E+ + G R A+++
Sbjct: 422 EAPAQAKPSGKAPQVRAASAPAKESPRK--------GAAPAPPRKTGPAAAQVQVGKQEE 473
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------------SS 2658
S SSS S S + ++ +++ S +S+ ++
Sbjct: 474 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
Query: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDE--AAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
S+ S ++ E+SS SSD E A AP S L K T K P
Sbjct: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG 593
Query: 2717 P---GKKTPAPQPQAPPPQPTQPLQPKAQA-GAKSRPKKREGVHLPTTKELAKR 2766
P K P + + + +A A + + + + +P TK K+
Sbjct: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
Score = 51.2 bits (121), Expect = 1e-05
Identities = 87/363 (23%), Positives = 129/363 (35%), Gaps = 57/363 (15%)
Query: 944 AEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAA 1003
+E EE+GS AA K G+ +AG + ++ GK P +AS V+
Sbjct: 171 SETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVST 230
Query: 1004 LKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLEL 1063
++ + P TP + PPA P EE E+ E + E
Sbjct: 231 KESPA----RKAAPAPGKVGDVTPQVKGGALPPAKRAKKP-----EEESESSEEGSESEE 281
Query: 1064 EKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPER 1123
E A + Q S+ L A+A A G PA +
Sbjct: 282 EAPAGTRSQVKASE------------------KILQVRAASAPAKGTPGKGATPAPPGKA 323
Query: 1124 LALSPE---DKPIRLSPSKITEPLREGPEEEPLAER--EVKAEVEDMDEGPTELPPLESP 1178
A++ + KP S S +E + EE P A+ + KA + G P ESP
Sbjct: 324 GAVASQTKAGKPEEDSESS-SEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESP 382
Query: 1179 LPLPAAEAMATPSPAGGCGGGLLEAQA--LSATGQSCAEPSECPDFVEGPEPRVDSPGRT 1236
A P+P G G + +AQA QS +E S+ + ++P +
Sbjct: 383 ------RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE---------EAPAQA 427
Query: 1237 EPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSE--SQPTLEMS 1294
+P A + P AKE P + P + P QV E S+ + E S
Sbjct: 428 KPSGKAPQVRAASAP-----AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 482
Query: 1295 DCD 1297
D D
Sbjct: 483 DSD 485
Score = 48.9 bits (115), Expect = 7e-05
Identities = 238/1285 (18%), Positives = 416/1285 (32%), Gaps = 190/1285 (14%)
Query: 917 QQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPP 976
+ A QA + + S + +E AE E + L + + L P + K
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 977 GLAAGPAGTYGKAVSPPP------------SPRASPVAALKAKVIQKLEDVSKPPAYAYP 1024
AG G ++ P SPR S + ++ + E+ PA+
Sbjct: 127 A-ETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
Query: 1025 ATPSSHPTSPPPASPPPTPGIT-----------RKEEAPENVVEKKDLELEKEAPSPFQA 1073
A P +S T + + + + V K+ K AP+P +
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
Query: 1074 LFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPE---- 1129
D+ P+ ALPP P + + + +G + PA ++ S +
Sbjct: 246 --GDVTPQVKGGALPPAKRAKKP---EEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 1130 ---DKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEA 1186
P + +P K P G ++ + ED + E +S PAA+A
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE--SSDSEEETPAAKA 358
Query: 1187 MATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLG 1246
+ +G S G + A E P P P PG+T P A G
Sbjct: 359 LLQAKASG----------KTSQVGAASAPAKESPRKGAAPAP----PGKTGPAVAKAQAG 404
Query: 1247 VQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGE---- 1302
+ ++ ++E E EE AQ PS P ++ PA E
Sbjct: 405 -KREEDSQSSSEESDSE------------EEAPAQAKPSGKAP--QVRAASAPAKESPRK 449
Query: 1303 GQCPSLEPQEAVPVLGSTCF----LEEASSDQFLPSLEDPLAGMNA--LAAAAELPQARP 1356
G P+ P++ P + SS + S + LA MNA + + PQ +P
Sbjct: 450 GAAPA-PPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
Query: 1357 LPSPG----AAGAQALEKLEAAESLVLEQSFLHGITLLSEIAELELERRSQEMGGAERAL 1412
+ G GA + + + Q + E +E E S G
Sbjct: 509 ASTMGMGPLGKGAGPVPPGKVGPATPSAQ-----VGKWEEDSESSSEESSDSSDGEVPTA 563
Query: 1413 VARPSLESLLAAGSHMLREVLDGPVVDPLKNLRLPRELKPNKKYSWMRKKEERMYAMKSS 1472
VA +SL G+ + + P P P++ P K + + + S
Sbjct: 564 VAPAQEKSL---GNILQAKPTSSPAKGP------PQKAGPVAVQVKAEKPMDNSESSEES 614
Query: 1473 LEDMDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDSEDRREEPHRSLARRGPGRPRKR 1532
+ D+ E M A+ + K Q + ++ + + P R G PRK
Sbjct: 615 SDSADSEEAPAAMTAAQAKPALKIPQTKACP-KKTNTTASAKVAP----VRVGTQAPRKA 669
Query: 1533 THAPS-ALSPPRKRGKSGHSSGKLSSKSLLTSDDYELGAGIRKRHKGSEEEHDALIGMGK 1591
A S A S P G + + SS S++ + G + +G K
Sbjct: 670 GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAV-------------TVGQAK 716
Query: 1592 ARGRNQTWDEHEASSDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDS 1651
+ G+ + +A+S + +K L K ++ K +K + + S+
Sbjct: 717 SVGKGL---QVKAAS-----VPVKGSLGQGTAPVLPGKTGPTVTQVKAEK-QEDSESSEE 767
Query: 1652 AGGKSKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKA 1711
+ + + T K A A+ S GK AA K
Sbjct: 768 ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQR----- 822
Query: 1712 RGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKA 1771
P P + +S + PA PS K + + +
Sbjct: 823 --SPSKVKPPVRNPQNS------------TVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 1772 AGGPKLTKRGLAAPRTLKPKPATSRKQPFCLL--LREAEARSSFSDSSEESFDQDESSEE 1829
+ + A + KP+ Q L +E+ + + ++ + +
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 928
Query: 1830 EDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQ 1889
+D+ EE ++ G + + P L SP GP+ + Q
Sbjct: 929 QDDSGSSSEESDSDGEAPAAVTSAQVIKPPL----------IFVDPNRSP-AGPAATPAQ 977
Query: 1890 LEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPG 1949
+A RK +S + ++ E + + G+ + P + AP
Sbjct: 978 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRI-APKAS 1036
Query: 1950 ARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASA 2009
G +S K + G+K GP + P + L + + ++ AS
Sbjct: 1037 MAG---ASSSKESSRISDGKKQ---EGPATQVSKKNPAS----LPLTQAALKVLAQKASE 1086
Query: 2010 AAPAPVSTAPATKTSRCAKGGP-LSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAP 2068
A P T P++ P SP+ + +AK RK P+ P
Sbjct: 1087 AQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRK---------------PKLP 1131
Query: 2069 ALPSEARAPHAS-----SLTAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFEP 2123
+ +AP +S S ++ S+ +G + K G S+ E++ E E
Sbjct: 1132 EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSR-TETLVEETAAES 1190
Query: 2124 NQDSSFSEDEHLPRGGAVERPLTPA 2148
++D + + L G + LTPA
Sbjct: 1191 SEDDVVAPSQSL-LSGYMTPGLTPA 1214
Score = 46.2 bits (108), Expect = 5e-04
Identities = 107/495 (21%), Positives = 162/495 (32%), Gaps = 79/495 (15%)
Query: 170 AGAPGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFG---KKDPR 226
AG G+ H + +T S +P K + P FG K
Sbjct: 132 AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 227 ARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPS----VLT 282
+ G+ S + E EG+ P ++ + S ES + AA P V
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEGKPSVKPAQV-KASSVSTKESPARKAAPAPGKVGDVTP 250
Query: 283 MCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTET------LLPGPRPCPSPLP 336
GGA A E ++E + +E A R++ L P+
Sbjct: 251 QVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGT 310
Query: 337 P----PPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIAS 392
P PAPP A + T AG E E + P+ +A + + S
Sbjct: 311 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGK-TS 369
Query: 393 QARDARAREREAGRPGVLQAPPGSPRPL--DRPEGLREKNSVIRSLKRPPPADAPTVRAT 450
Q A A +E+ R G APPG P G RE++S S + +AP
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP----- 424
Query: 451 RASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKW 510
A +P +AP+ A A + + G P P TGP
Sbjct: 425 -------------------AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGP---- 461
Query: 511 KPFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVA 570
AA Q+ V Q SR+ E + + A ++ V P + +P +
Sbjct: 462 --------AAAQVQV-GKQEEDSRSSSEES--DSDREALAAMNAAQVKPLGKSPQVKPAS 510
Query: 571 DMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAPTSAGA 630
M G G A V PG G +P +G + + +S +
Sbjct: 511 TMGMGPLGKG------------------AGPVPPGKVGPATPSAQVGKWEEDSESSSEES 552
Query: 631 S-RAQARLPHSGGPA 644
S + +P + PA
Sbjct: 553 SDSSDGEVPTAVAPA 567
Score = 46.2 bits (108), Expect = 5e-04
Identities = 257/1327 (19%), Positives = 412/1327 (31%), Gaps = 236/1327 (17%)
Query: 1505 QRRRDSEDRREEPHRSLARRGPGRPRKRT-HAPSALSPPRKRGKSGHSSGKLSSKSLLTS 1563
Q + S +E P R A PG+ T PP KR K + S + +
Sbjct: 222 QVKASSVSTKESPARKAAP-APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEG--SE 278
Query: 1564 DDYELGAGIRKRHKGSEEEHDALIGMGKARG---RNQTWDEHEASSDFISQLKIKK---- 1616
+ E AG R + K SE+ A+G + T + SQ K K
Sbjct: 279 SEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEED 338
Query: 1617 ------KKMASDQEQLASKL---DKALSLTKQ-DKLKSPFKFSDSAGGKSKTSGGCGRYL 1666
+ S++E A+K KA T Q +P K S G G G +
Sbjct: 339 SESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV 398
Query: 1667 TPY-------DSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFK-ARGQPKSA 1718
DS + K S + RAA E K A P
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRK 458
Query: 1719 HSPFASEVSSYSYNTDSEED-EEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKL 1777
P A++V DS EE D +++++ P V S GP
Sbjct: 459 TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLG 518
Query: 1778 TKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELE 1837
G P + P +++ + E ++ SS +SS+ S + ++ +E+ L
Sbjct: 519 KGAGPVPPGKVGPATPSAQVGKW-----EEDSESSSEESSDSSDGEVPTAVAPAQEKSLG 573
Query: 1838 E-------EDEASGGGYRLGA------RERAL--SPGLEESGLGLLARFAASALPSPTVG 1882
A G + G E+ + S EES + A +A+ +
Sbjct: 574 NILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK 633
Query: 1883 PSLSVVQLEA-------------------KQKARKKEERQSLLGT------------EFE 1911
P+L + Q +A Q RK S G+ E
Sbjct: 634 PALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDS 693
Query: 1912 YTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPG----ARGPDPSSPDKAKLAVEK 1967
+ ES+ + K A + K +G+ AA P +G P P K
Sbjct: 694 SSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKT------ 747
Query: 1968 GRKARKLRGPKEPGFEAGPEASDDD--------LWTRRRSERIFLHDASAAAPAPVST-- 2017
G +++ K+ E+ E SD + + T + + + A+A AP+ T
Sbjct: 748 GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTIS 807
Query: 2018 APATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPP---------PRAP 2068
AP + A+ SP K ++ ++ +G + P G P
Sbjct: 808 APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEED 867
Query: 2069 ALPSEARAPHASSLTAAKRSKAKAKGKEVK------KENRGKGGAVSKLMESMAAEEDFE 2122
+ SE + + K K +++ KE+ KG A + ++ +
Sbjct: 868 SGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 927
Query: 2123 PNQDSSFSEDEHLPRG---GAVERPLTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHV 2179
DS S +E G AV P +D + G
Sbjct: 928 KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAAT---------PAQA 978
Query: 2180 QTVHSPDIYRVVVEGERGNR---------PHIYCLEQLLQEAIIDVRPASTRFLPQGTRI 2230
Q +P R R + P CL ++ ++ + A R P+ +
Sbjct: 979 QAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMA 1038
Query: 2231 AAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAE 2290
A S++ + G G + + +PL+ L K A+
Sbjct: 1039 GASSSKESSRISDGKKQEGP----------ATQVSKKNPASLPLTQAALKVLAQKASEAQ 1088
Query: 2291 PSPALLVPSA-------------------------KRRSRKT-----------SKDTGEG 2314
P A PS+ K R K S D E
Sbjct: 1089 PPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSED 1148
Query: 2315 KDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDE------VPSTPL------ 2362
++GSEE G +G + R TL E + PS L
Sbjct: 1149 SSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMT 1208
Query: 2363 -ALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATS 2421
L P+++ SK +P +D A P A P+ A + +P T
Sbjct: 1209 PGLTPANSQASKATPK--LDSSPSVSSTLAAKDDPDGKQEA-----KPQQAAGMLSPKTG 1261
Query: 2422 LAPAPLITMPATRPKPKKARAAEESGAK-----------GPRRPGEEAELLVKLDHEGVT 2470
A T P KPKK ++ G P EA++ + + +T
Sbjct: 1262 GKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV-KVLT 1320
Query: 2471 SPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPG 2530
++ K+ + ++ GW+ K LS G P A + P K A E G
Sbjct: 1321 ELLEQERKKVVDTTKESSRKGWESRKRKLS-GDQPAA------RTPRSKKKKKLGAGEGG 1373
Query: 2531 PGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKN 2590
+ + S KA+ ++ + E S GS G++ E EEE K
Sbjct: 1374 EASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ---------GAKDEPEEELQK- 1423
Query: 2591 GDGGCGT-GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2649
G GT G + S S+ S + +S+ S S S
Sbjct: 1424 ---GMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKK 1480
Query: 2650 SSSSSSS 2656
++ +
Sbjct: 1481 KKTAEQT 1487
>gi|8923106 zinc finger, CCHC domain containing 10 [Homo sapiens]
Length = 170
Score = 81.3 bits (199), Expect = 1e-14
Identities = 50/85 (58%), Positives = 62/85 (72%), Gaps = 4/85 (4%)
Query: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2659
R+ S SS ++S SS+S SSS S +S+SSSS S + SSSSSSSS+SS++SSSSS S
Sbjct: 82 RSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDS 141
Query: 2660 SSSSSSSSSSSSTTDEDSSCSSDDE 2684
S SSSSSSSS++TD SSDDE
Sbjct: 142 DSDSSSSSSSSTSTDS----SSDDE 162
Score = 79.0 bits (193), Expect = 7e-14
Identities = 46/86 (53%), Positives = 58/86 (67%)
Query: 2604 AASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2663
A R+ S SSSSSSS SS+S SSS S +S+SSSS S + SSSSSSSS+SS++SSS
Sbjct: 78 AKKKRSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSS 137
Query: 2664 SSSSSSSSTTDEDSSCSSDDEAAPAP 2689
SS S S S++ SS S+D + P
Sbjct: 138 SSDSDSDSSSSSSSSTSTDSSSDDEP 163
Score = 77.8 bits (190), Expect = 1e-13
Identities = 45/82 (54%), Positives = 57/82 (69%)
Query: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665
S S +SSSS SS+S SSS S +S+SSSS S + SSSSSSSS+SS++SSSSS S
Sbjct: 83 SKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDSD 142
Query: 2666 SSSSSSTTDEDSSCSSDDEAAP 2687
S SSSS++ S+ SS D+ P
Sbjct: 143 SDSSSSSSSSTSTDSSSDDEPP 164
Score = 76.6 bits (187), Expect = 3e-13
Identities = 45/79 (56%), Positives = 55/79 (69%)
Query: 2608 RAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2667
R A S S +SSSSSSS SS+S SSS S +S+SSSS S + SSSSSSSS+SS++S
Sbjct: 76 RKAKKKRSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTS 135
Query: 2668 SSSSTTDEDSSCSSDDEAA 2686
SSSS +D DSS SS +
Sbjct: 136 SSSSDSDSDSSSSSSSSTS 154
Score = 72.0 bits (175), Expect = 8e-12
Identities = 51/111 (45%), Positives = 63/111 (56%), Gaps = 29/111 (26%)
Query: 2554 AEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPA 2613
A++ S S +SS SSSS SS+S S SE+E
Sbjct: 78 AKKKRSKSVTSSSSSSSDSSASDSSSESE-----------------------------ET 108
Query: 2614 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2664
S+SSSS S + SSSSSSSS+SS++SSSSS S S SSSSSSSS+S+ SSS
Sbjct: 109 STSSSSEDSDTDESSSSSSSSASSTTSSSSSDSDSDSSSSSSSSTSTDSSS 159
Score = 68.9 bits (167), Expect = 7e-11
Identities = 40/88 (45%), Positives = 56/88 (63%)
Query: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSS 2678
S S +SSSSSSS SS+S SSS S +S+SSSS S + SSSSSSSS+SS++S++ DS
Sbjct: 83 SKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDSD 142
Query: 2679 CSSDDEAAPAPTAGPSAQAALPTKATKQ 2706
S ++ + + S+ P K K+
Sbjct: 143 SDSSSSSSSSTSTDSSSDDEPPKKKKKK 170
Score = 67.4 bits (163), Expect = 2e-10
Identities = 39/87 (44%), Positives = 56/87 (64%)
Query: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
S S +SSSSSSS SS+S SSS S +S+SSSS S + SSSSSSSS+S+T SS SD
Sbjct: 83 SKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDSD 142
Query: 2683 DEAAPAPTAGPSAQAALPTKATKQAGK 2709
+++ + ++ S ++ + K+ K
Sbjct: 143 SDSSSSSSSSTSTDSSSDDEPPKKKKK 169
Score = 60.5 bits (145), Expect = 2e-08
Identities = 48/133 (36%), Positives = 63/133 (47%), Gaps = 30/133 (22%)
Query: 2519 KATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSG 2578
K + L + G T + K K+ + S+S SSS S +S+SSSS
Sbjct: 57 KEKENRLLLQQSIGETNVERKAKKKRSKSVTSSSSSSSDSSASDSSSESEETSTSSSSED 116
Query: 2579 SETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSS 2638
S+T+ SSSSSSSS+SS++SSSSS S S SS
Sbjct: 117 SDTD------------------------------ESSSSSSSSASSTTSSSSSDSDSDSS 146
Query: 2639 SSSSSSSSSSSSS 2651
SSSSSS+S+ SSS
Sbjct: 147 SSSSSSTSTDSSS 159
Score = 55.5 bits (132), Expect = 8e-07
Identities = 34/99 (34%), Positives = 50/99 (50%)
Query: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSS 2681
S ++ + S S +SSSSSSS SS+S SSS S +S+SSSS S TDE SS SS
Sbjct: 68 SIGETNVERKAKKKRSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSS 127
Query: 2682 DDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKK 2720
++ ++ + + + ++ S P KK
Sbjct: 128 SSASSTTSSSSSDSDSDSSSSSSSSTSTDSSSDDEPPKK 166
Score = 45.1 bits (105), Expect = 0.001
Identities = 29/129 (22%), Positives = 53/129 (41%)
Query: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
C+ P+ ++ + + S ++ + S S +SSSSSSS
Sbjct: 36 CTGKRKYLHRPSRTAELKKALKEKENRLLLQQSIGETNVERKAKKKRSKSVTSSSSSSSD 95
Query: 2662 SSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
SS+S SSS S SS S D + + ++ S+ ++ + ++ + S+ S T
Sbjct: 96 SSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDSDSDSSSSSSSSTST 155
Query: 2722 PAPQPQAPP 2730
+ PP
Sbjct: 156 DSSSDDEPP 164
Score = 43.5 bits (101), Expect = 0.003
Identities = 27/98 (27%), Positives = 46/98 (46%)
Query: 2635 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPS 2694
S ++ + S S +SSSSSSS SS+S SSS + + +S SS+D ++ S
Sbjct: 68 SIGETNVERKAKKKRSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSS 127
Query: 2695 AQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQ 2732
+ A+ T ++ + S+ S + PP+
Sbjct: 128 SSASSTTSSSSSDSDSDSSSSSSSSTSTDSSSDDEPPK 165
Score = 40.8 bits (94), Expect = 0.020
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 16/137 (11%)
Query: 2453 RPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSE 2512
RP AEL L K+ + LLL++ G + S ++ SS
Sbjct: 45 RPSRTAELKKAL----------KEKENRLLLQQSIGETNVERKAKKKRSKSVTSSSSSSS 94
Query: 2513 PKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSS 2572
+ +++ ++E + EDS +S + + A + SSSSS S S SSSS
Sbjct: 95 DSSASDSSSE---SEETSTSSSSEDSDTDES---SSSSSSSASSTTSSSSSDSDSDSSSS 148
Query: 2573 SSSSSGSETEGEEEGDK 2589
SSSS+ +++ ++E K
Sbjct: 149 SSSSTSTDSSSDDEPPK 165
Score = 35.8 bits (81), Expect = 0.65
Identities = 20/57 (35%), Positives = 27/57 (47%)
Query: 2536 EDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGD 2592
E S ++ D + S SSS+SS+ SSSSS S S S S + D + D
Sbjct: 104 ESEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDSDSDSSSSSSSSTSTDSSSD 160
>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
Length = 737
Score = 80.5 bits (197), Expect = 2e-14
Identities = 64/196 (32%), Positives = 108/196 (55%), Gaps = 26/196 (13%)
Query: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616
S SS+SSSS +SS+S+SS + S T ++S +S +S+
Sbjct: 112 SNSSTSSSSTTSSTSTSSFITSSFTTSTS-----------------ITSTSSTSSFTTST 154
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDED 2676
+++S+S S +S+SS SSS +S+S+S++S+SS+S++S+ +S+S+S+S+S+S+S+SST
Sbjct: 155 ATTSTSISITSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTST 214
Query: 2677 SSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAH--------SPGKKTPAPQPQA 2728
+S S+ + + + ++ T KQ G A SA S G K
Sbjct: 215 TSTSTTSTSTTSTSTSATSSIRKLTPHQKQCG-ALASAFLFGLSLLVSTGTKGLGRSLVT 273
Query: 2729 PPPQPTQPLQPKAQAG 2744
P P P PL P+A++G
Sbjct: 274 PRPSPPPPLTPQAESG 289
Score = 53.5 bits (127), Expect = 3e-06
Identities = 35/115 (30%), Positives = 67/115 (58%)
Query: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666
S +PA S S + +S+SS+SSSS++SS+S+SS +SS ++S+S +S+SS+SS
Sbjct: 91 SSTITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSF 150
Query: 2667 SSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
++S++TT S +S + + T+ ++ + + +T + ++ S T
Sbjct: 151 TTSTATTSTSISITSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTSTSTST 205
Score = 45.1 bits (105), Expect = 0.001
Identities = 30/78 (38%), Positives = 49/78 (62%)
Query: 2604 AASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2663
A S+ PAS+ S+S SS+ + + S S + +S+SS+SSSS++SS+S+SS
Sbjct: 72 ATSATRPPPASNEVSTSVLSSTITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFI 131
Query: 2664 SSSSSSSSTTDEDSSCSS 2681
+SS ++S++ SS SS
Sbjct: 132 TSSFTTSTSITSTSSTSS 149
Score = 35.0 bits (79), Expect = 1.1
Identities = 70/271 (25%), Positives = 97/271 (35%), Gaps = 32/271 (11%)
Query: 442 ADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRP 501
A P+ RA ++P P A + R R GPAA A +++ R
Sbjct: 464 ARLPSRRARSSAPAPSAQGRCMTPARSPVAAREAARLRGARPGPAASAATRMWQGSGRRR 523
Query: 502 PPTGPEHKWKPFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAVLPRS 561
P GP+ P EL L S+ V +A L G +LPR+
Sbjct: 524 P--GPD----PQELDPHCKLSFPRLPLTPTESQPPSHNLFVEELRGARAALARGWMLPRA 577
Query: 562 --AATC-----GRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFG 614
C RP + +AA GS E+S++ SG AR A+ + C ++
Sbjct: 578 LRRQLCPIDPRARPGSVAPAAASGSIESSSL------SGRAARLALG-KHRACLRRGTEA 630
Query: 615 GLGTMKPEPAPTSAGASR-------AQARLPHSGGPAAGGGRQLKRDPERPESAKAFGRE 667
G + E G +R A + PH G GR R + A F
Sbjct: 631 GRPRLAGERRGAGDGRARDFRRIALAAPQFPHLESNTLGRGR--PRPGDWALQATDFPDA 688
Query: 668 GSGAQGEAEVRHPPVGIA---VAVARQKDSG 695
A G A R P VG A A A ++D G
Sbjct: 689 TKPALGAALRRGPIVGPAAGFAAPAAERDPG 719
Score = 34.7 bits (78), Expect = 1.4
Identities = 56/227 (24%), Positives = 79/227 (34%), Gaps = 43/227 (18%)
Query: 2326 GAKARGRGRKPSA----KAKGDRAATLEEGNPTDEVPSTPLALEPSSTPG---------- 2371
G R R P+ +A R LE G VPS +A + PG
Sbjct: 375 GLGLRSRSESPAGQCVLRASQQRGVRLEGGGRQQLVPSQ-VAWRAARAPGRHQAAVLRRR 433
Query: 2372 ------SKKSPPEPVDKRAKAPKARPAPPQPS-PAPPAFTSCPAPEPFAELPAPATS-LA 2423
+++ V +AP+A A P+ A +S PAP PA S +A
Sbjct: 434 RARVARAQQLARLRVGHAVQAPQALQAQLHARLPSRRARSSAPAPSAQGRCMTPARSPVA 493
Query: 2424 PAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELL-----VKLDHEGVTSPKSKKAK 2478
+ RP P + A G RRPG + + L + +T +S+
Sbjct: 494 AREAARLRGARPGPAASAATRMWQGSGRRRPGPDPQELDPHCKLSFPRLPLTPTESQPPS 553
Query: 2479 EALLLREDPG-----AGGWQEPKSL----------LSLGSYPPAAGS 2510
L + E G A GW P++L GS PAA S
Sbjct: 554 HNLFVEELRGARAALARGWMLPRALRRQLCPIDPRARPGSVAPAAAS 600
>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
Length = 737
Score = 80.5 bits (197), Expect = 2e-14
Identities = 64/196 (32%), Positives = 108/196 (55%), Gaps = 26/196 (13%)
Query: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616
S SS+SSSS +SS+S+SS + S T ++S +S +S+
Sbjct: 112 SNSSTSSSSTTSSTSTSSFITSSFTTSTS-----------------ITSTSSTSSFTTST 154
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDED 2676
+++S+S S +S+SS SSS +S+S+S++S+SS+S++S+ +S+S+S+S+S+S+S+SST
Sbjct: 155 ATTSTSISITSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTST 214
Query: 2677 SSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAH--------SPGKKTPAPQPQA 2728
+S S+ + + + ++ T KQ G A SA S G K
Sbjct: 215 TSTSTTSTSTTSTSTSATSSIRKLTPHQKQCG-ALASAFLFGLSLLVSTGTKGLGRSLVT 273
Query: 2729 PPPQPTQPLQPKAQAG 2744
P P P PL P+A++G
Sbjct: 274 PRPSPPPPLTPQAESG 289
Score = 53.5 bits (127), Expect = 3e-06
Identities = 35/115 (30%), Positives = 67/115 (58%)
Query: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666
S +PA S S + +S+SS+SSSS++SS+S+SS +SS ++S+S +S+SS+SS
Sbjct: 91 SSTITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSF 150
Query: 2667 SSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
++S++TT S +S + + T+ ++ + + +T + ++ S T
Sbjct: 151 TTSTATTSTSISITSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTSTSTST 205
Score = 45.1 bits (105), Expect = 0.001
Identities = 30/78 (38%), Positives = 49/78 (62%)
Query: 2604 AASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2663
A S+ PAS+ S+S SS+ + + S S + +S+SS+SSSS++SS+S+SS
Sbjct: 72 ATSATRPPPASNEVSTSVLSSTITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFI 131
Query: 2664 SSSSSSSSTTDEDSSCSS 2681
+SS ++S++ SS SS
Sbjct: 132 TSSFTTSTSITSTSSTSS 149
Score = 35.0 bits (79), Expect = 1.1
Identities = 70/271 (25%), Positives = 97/271 (35%), Gaps = 32/271 (11%)
Query: 442 ADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRP 501
A P+ RA ++P P A + R R GPAA A +++ R
Sbjct: 464 ARLPSRRARSSAPAPSAQGRCMTPARSPVAAREAARLRGARPGPAASAATRMWQGSGRRR 523
Query: 502 PPTGPEHKWKPFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAVLPRS 561
P GP+ P EL L S+ V +A L G +LPR+
Sbjct: 524 P--GPD----PQELDPHCKLSFPRLPLTPTESQPPSHNLFVEELRGARAALARGWMLPRA 577
Query: 562 --AATC-----GRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFG 614
C RP + +AA GS E+S++ SG AR A+ + C ++
Sbjct: 578 LRRQLCPIDPRARPGSVAPAAASGSIESSSL------SGRAARLALG-KHRACLRRGTEA 630
Query: 615 GLGTMKPEPAPTSAGASR-------AQARLPHSGGPAAGGGRQLKRDPERPESAKAFGRE 667
G + E G +R A + PH G GR R + A F
Sbjct: 631 GRPRLAGERRGAGDGRARDFRRIALAAPQFPHLESNTLGRGR--PRPGDWTLQATDFPDA 688
Query: 668 GSGAQGEAEVRHPPVGIA---VAVARQKDSG 695
A G A R P VG A A A ++D G
Sbjct: 689 TKPALGAALRRGPIVGPAAGFAAPAAERDPG 719
Score = 34.7 bits (78), Expect = 1.4
Identities = 56/227 (24%), Positives = 79/227 (34%), Gaps = 43/227 (18%)
Query: 2326 GAKARGRGRKPSA----KAKGDRAATLEEGNPTDEVPSTPLALEPSSTPG---------- 2371
G R R P+ +A R LE G VPS +A + PG
Sbjct: 375 GLGLRSRSESPAGQCVLRASQQRGVRLEGGGRQQLVPSQ-VAWRAARAPGRHQAAVLRRR 433
Query: 2372 ------SKKSPPEPVDKRAKAPKARPAPPQPS-PAPPAFTSCPAPEPFAELPAPATS-LA 2423
+++ V +AP+A A P+ A +S PAP PA S +A
Sbjct: 434 RARVARAQQLARLRVGHAVQAPQALQAQLHARLPSRRARSSAPAPSAQGRCMTPARSPVA 493
Query: 2424 PAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELL-----VKLDHEGVTSPKSKKAK 2478
+ RP P + A G RRPG + + L + +T +S+
Sbjct: 494 AREAARLRGARPGPAASAATRMWQGSGRRRPGPDPQELDPHCKLSFPRLPLTPTESQPPS 553
Query: 2479 EALLLREDPG-----AGGWQEPKSL----------LSLGSYPPAAGS 2510
L + E G A GW P++L GS PAA S
Sbjct: 554 HNLFVEELRGARAALARGWMLPRALRRQLCPIDPRARPGSVAPAAAS 600
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 80.5 bits (197), Expect = 2e-14
Identities = 50/76 (65%), Positives = 56/76 (73%)
Query: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2662
S + RA + S S S SSSSSSSSSSS+SSSS SSSSS SSSS SSSSSSSS+S SSS
Sbjct: 560 SRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSR 619
Query: 2663 SSSSSSSSSTTDEDSS 2678
SSSS+SSS+ S
Sbjct: 620 DSSSSTSSSSESRSRS 635
Score = 79.3 bits (194), Expect = 5e-14
Identities = 49/74 (66%), Positives = 56/74 (75%)
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
T R+ A ++ + S SSSSSSSSSSS+SSSS SSSSS SSSS SSSSSSSS+S SS
Sbjct: 558 TRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSS 617
Query: 2657 SSSSSSSSSSSSSS 2670
S SSSS+SSSS S
Sbjct: 618 SRDSSSSTSSSSES 631
Score = 79.0 bits (193), Expect = 7e-14
Identities = 49/74 (66%), Positives = 55/74 (74%)
Query: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666
SR+ A + +S S S SSSSSSSSSSS+SSSS SSSSS SSSS SSSSSSSS+S SSS
Sbjct: 560 SRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSR 619
Query: 2667 SSSSSTTDEDSSCS 2680
SSSST+ S S
Sbjct: 620 DSSSSTSSSSESRS 633
Score = 78.6 bits (192), Expect = 9e-14
Identities = 50/76 (65%), Positives = 57/76 (75%)
Query: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
T R+ S +R + S S SSSSSSSSSSS+SSSS SSSSS SSSS SSSSSSSS+S
Sbjct: 556 TKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSG 615
Query: 2657 SSSSSSSSSSSSSSST 2672
SSS SSSS+SSSS +
Sbjct: 616 SSSRDSSSSTSSSSES 631
Score = 78.6 bits (192), Expect = 9e-14
Identities = 49/74 (66%), Positives = 56/74 (75%)
Query: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666
SR + +S S S SSSSSSSSSSS+SSSS SSSSS SSSS SSSSSSSS+S SSS S
Sbjct: 562 SRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDS 621
Query: 2667 SSSSSTTDEDSSCS 2680
SSS+S++ E S S
Sbjct: 622 SSSTSSSSESRSRS 635
Score = 76.6 bits (187), Expect = 3e-13
Identities = 47/72 (65%), Positives = 54/72 (75%)
Query: 2596 GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2655
G S + SR++S +SSSSSS+SSSS SSSSS SSSS SSSSSSSS+S SSS SSS
Sbjct: 564 GRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSS 623
Query: 2656 SSSSSSSSSSSS 2667
S+SSSS S S S
Sbjct: 624 STSSSSESRSRS 635
Score = 76.6 bits (187), Expect = 3e-13
Identities = 48/72 (66%), Positives = 54/72 (75%)
Query: 2599 GRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2658
GR + S + +SSSSSSSSS+SSSS SSSSS SSSS SSSSSSSS+S SSS SSS
Sbjct: 564 GRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSS 623
Query: 2659 SSSSSSSSSSSS 2670
S+SSSS S S S
Sbjct: 624 STSSSSESRSRS 635
Score = 76.6 bits (187), Expect = 3e-13
Identities = 48/77 (62%), Positives = 56/77 (72%)
Query: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2659
RN ++ S +S +SSSSSSS+SSSS SSSSS SSSS SSSSSSSS+S SSS SSSS+S
Sbjct: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
Query: 2660 SSSSSSSSSSSSTTDED 2676
SSS S S S + D
Sbjct: 627 SSSESRSRSRGRGHNRD 643
Score = 76.3 bits (186), Expect = 4e-13
Identities = 56/154 (36%), Positives = 80/154 (51%), Gaps = 3/154 (1%)
Query: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2662
S +R+ S + + +S S S SSSSSSSSSSS+SSSS SSSSS SSSS SSSSSSSS+
Sbjct: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
Query: 2663 SSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPG---K 2719
S SSS SS++ SS S + ++ K +G R S G +
Sbjct: 614 SGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSR 673
Query: 2720 KTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKRE 2753
T + + + + +++G +S +R+
Sbjct: 674 DTKGSKDKNSRSDRKRSISESSRSGKRSSRSERD 707
Score = 69.7 bits (169), Expect = 4e-11
Identities = 60/164 (36%), Positives = 76/164 (46%), Gaps = 37/164 (22%)
Query: 2542 KSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRN 2601
KS K ++ G +++S S S SSSSSSSSSS+ S
Sbjct: 553 KSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSS---------------------- 590
Query: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
SS SSSSS SSSS SSSSSSSS+S SSS SSSS+SSSS S S S
Sbjct: 591 ------------SSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGR 638
Query: 2662 SSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATK 2705
+ + D +S E + + G S++ TK +K
Sbjct: 639 GHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSR---DTKGSK 679
Score = 67.8 bits (164), Expect = 2e-10
Identities = 40/80 (50%), Positives = 53/80 (66%)
Query: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
P S S + + S S + + +S S S SSSSSSSSSSS+SSSS SSSSS SSSS SSSSS
Sbjct: 550 PESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSS 609
Query: 2672 TTDEDSSCSSDDEAAPAPTA 2691
++ S S D ++ + ++
Sbjct: 610 SSSTSGSSSRDSSSSTSSSS 629
Score = 67.0 bits (162), Expect = 3e-10
Identities = 52/123 (42%), Positives = 61/123 (49%), Gaps = 36/123 (29%)
Query: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599
+P+S K + + + +S S SSSSSSSSSS
Sbjct: 549 HPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSS---------------------- 586
Query: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2659
S+SSSS SSSSS SSSS SSSSSSSS+S SSS SSSS+SSSS S
Sbjct: 587 --------------STSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESR 632
Query: 2660 SSS 2662
S S
Sbjct: 633 SRS 635
Score = 63.2 bits (152), Expect = 4e-09
Identities = 41/106 (38%), Positives = 62/106 (58%)
Query: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
S S + + S S + + +S S S SSSSSSSSSSS+SSSS SSSSS SSSS SSS++
Sbjct: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
Query: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
+S SS +++ + ++ +++ + + K R S + T
Sbjct: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDT 657
Score = 60.5 bits (145), Expect = 2e-08
Identities = 43/148 (29%), Positives = 59/148 (39%), Gaps = 3/148 (2%)
Query: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599
N S ++++ + S S+SSSS SSSS SSSS S S + G + D T
Sbjct: 568 NKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSS 627
Query: 2600 RNCSAASSRAAS---PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
+ S + SR S +S S SS SS + S +S S
Sbjct: 628 SSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDR 687
Query: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDE 2684
S S SS S SS ++ D D+
Sbjct: 688 KRSISESSRSGKRSSRSERDRKSDRKDK 715
Score = 60.1 bits (144), Expect = 3e-08
Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 39/323 (12%)
Query: 2358 PSTPLALEP-----SSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPF 2412
P +EP S +PG + ++K ++ + + + PQP P P+P
Sbjct: 427 PEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQ-------PQPQ 479
Query: 2413 AELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSP 2472
++ S + L + P ++P+ + + P+ E+ LL + V S
Sbjct: 480 SQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPT----PQVTQEQGHLLPERKDFPVESV 535
Query: 2473 KSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPG 2532
K + +L P E KS S + G + K ++
Sbjct: 536 KLTEVPVEPVLTVHP------ESKSKTKTRSR--SRGRARNKTSKSRS------------ 575
Query: 2533 LTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGD 2592
S + S + + G+ S SSSS S SSSSSS+S SS ++
Sbjct: 576 ---RSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESR 632
Query: 2593 GGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2652
G N R+ +S S SS SS + S +S S S S
Sbjct: 633 SRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSIS 692
Query: 2653 SSSSSSSSSSSSSSSSSSSTTDE 2675
SS S SS S S D+
Sbjct: 693 ESSRSGKRSSRSERDRKSDRKDK 715
Score = 58.9 bits (141), Expect = 7e-08
Identities = 39/109 (35%), Positives = 60/109 (55%), Gaps = 7/109 (6%)
Query: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
P + S S + + S S + + +S S S SSSSSSSSSSS+SSSS SSSSS SSSS
Sbjct: 544 PVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSS 603
Query: 2672 TTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKK 2720
+ SS S+ ++ ++ S+ +++ ++R H+ +K
Sbjct: 604 RSSSSSSSSTSGSSSRDSSSSTSS-------SSESRSRSRGRGHNRDRK 645
Score = 32.0 bits (71), Expect = 9.4
Identities = 39/159 (24%), Positives = 64/159 (40%), Gaps = 6/159 (3%)
Query: 1697 KRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKL 1756
K KTR G +AR + + S +S SS S +T S ++ SSS
Sbjct: 553 KSKTKTRSRSRG-RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
Query: 1757 TPSLLCSMVAKNSKAAGGPKLTK-RGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSD 1815
+ S S + +S ++ ++ RG R K + + RK+ L E +SS
Sbjct: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL-ERSHKSSKGG 670
Query: 1816 SSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARER 1854
SS ++ + + D + + E+S G R ER
Sbjct: 671 SSRDTKGSKDKNSRSDRKRSI---SESSRSGKRSSRSER 706
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 80.1 bits (196), Expect = 3e-14
Identities = 111/411 (27%), Positives = 149/411 (36%), Gaps = 69/411 (16%)
Query: 990 VSPPPS-------PRASPVAALKAKVIQKLEDVSKPPAYAYPATP--SSHPTSPP----P 1036
+SPPP P +SP + L+ + E+ PA P +P + P SPP P
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP 553
Query: 1037 ASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYP 1096
SPPP EE P + E + +P P ++ S P P PP R +P
Sbjct: 554 LSPPP-------EELPTSPPP----EASRLSPPPEESPMSPPPEESPMSP-PPEASRLFP 601
Query: 1097 FL-------------LQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEP 1143
L P A P+ + PE +SP + RLSP +
Sbjct: 602 PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR 661
Query: 1144 LREGPEEEPLAEREVKAEVEDMDEGPTELPPLE-SPLPLPAAEAMATPSPAGGCGGGLLE 1202
L PEE PL+ ++ E PP E SP P ++ A+P P LE
Sbjct: 662 LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLE 721
Query: 1203 AQALSATGQSCAEPSECPDFVEGP--EPRVD----SPGRTEPCTAALDLGVQLTPE---- 1252
L + EP CP EGP PR + SP EP + L+P+
Sbjct: 722 ESPLLPLPE---EPQLCPR-SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEP 777
Query: 1253 TLVEAKEEPVEVPVAV-PVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQ 1311
L EEP P A P + PEE ++P +P L P E C S +P+
Sbjct: 778 CLCAVPEEPHLSPQAEGPHLSPQPEE--LHLSPQTEEPHLS------PVPEEPCLSPQPE 829
Query: 1312 EA--VPVLGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSP 1360
E+ P C P LE P L+ E P P P
Sbjct: 830 ESHLSPQSEEPCLSPRPEESHLSPELEKP-----PLSPRPEKPPEEPGQCP 875
Score = 76.6 bits (187), Expect = 3e-13
Identities = 104/415 (25%), Positives = 147/415 (35%), Gaps = 60/415 (14%)
Query: 972 PRKPPGLA--AGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSS 1029
P++P L A P G G + P L+A + +++ + P P
Sbjct: 406 PKEPGPLQCEAKPLGKAGVQLEPQ----------LEAPLNEEMPLLPPPEESPLSPPPEE 455
Query: 1030 HPTSPPP----ASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQ 1085
PTSPPP SPPP PE + + LE +P P ++ S P PF
Sbjct: 456 SPTSPPPEASRLSPPPEE--LPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFS 513
Query: 1086 AL------PPHYGRPYPFLLQP-TAAADADGLAP---DVPLPADGPERLALSPEDKPIRL 1135
L PP P P L P + +A L+P + PL + PE L SP + RL
Sbjct: 514 PLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL-SPPPEELPTSPPPEASRL 572
Query: 1136 SPSKITEPLREGPEEEPLA-EREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAG 1194
SP P+ PEE P++ E +E P PP ESPL P + +P P
Sbjct: 573 SPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP-- 630
Query: 1195 GCGGGLLEAQALSATGQSCAEPSECPDFVEGPEP-----RVDSPGRTEPCTAALDLGVQL 1249
E +S + P P V P R+ P P + +
Sbjct: 631 -------EDSPMSPPPEE--SPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS 681
Query: 1250 TPETLVEAKEEPVEVPVAVPVVEA----VPEEGLAQVAPSESQPTLEMSDCDVPAGEGQC 1305
P P + P + P ++ PE+ L + P E P L + + +
Sbjct: 682 PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL-PLEESPLLPLPEEPQLCPRSEG 740
Query: 1306 PSLEPQEAVPVLG----STCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARP 1356
P L P+ P L +A P E+P L A E P P
Sbjct: 741 PHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEP-----CLCAVPEEPHLSP 790
Score = 56.2 bits (134), Expect = 5e-07
Identities = 109/431 (25%), Positives = 143/431 (33%), Gaps = 80/431 (18%)
Query: 990 VSPPPS-PRASPVAALKAKVIQKLEDVSKPPAYAYPATP-----------SSHPTSPPP- 1036
+SPPP R SP+ + E PP P +P PTSPPP
Sbjct: 644 MSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPE 703
Query: 1037 ---ASPPPT----------------------------PGITRKEEAPENVVEKKDLELEK 1065
ASPPP P ++ + E P ++ L
Sbjct: 704 DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSP 763
Query: 1066 EA------PSPFQALFSDIP--PRYPFQALPPHYG-RPYPFLLQPTAAADADGLAPDVPL 1116
+A P P + +P P QA PH +P L P P+ P
Sbjct: 764 QAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPC 823
Query: 1117 PADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAER-EVKAEVEDMDEGPTEL--- 1172
+ PE LSP+ + LSP L E+ PL+ R E E P EL
Sbjct: 824 LSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF 883
Query: 1173 PPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDS 1232
PP P P A P L E LS +G+ P P P P S
Sbjct: 884 PPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP---PDPLPPPLS 940
Query: 1233 PGRTEPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLE 1292
P T AL +L + +P E P+A P++E P P
Sbjct: 941 PIITAAAPPALSPLGELEYPFGAKGDSDP-ESPLAAPILE----------TPISPPPEAN 989
Query: 1293 MSDCD-VPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAEL 1351
+D + VP L P PV ++ L E Q P L+ L N+ +
Sbjct: 990 CTDPEPVPP-----MILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCS- 1043
Query: 1352 PQARPL--PSP 1360
P A PL PSP
Sbjct: 1044 PPALPLSVPSP 1054
Score = 53.5 bits (127), Expect = 3e-06
Identities = 71/288 (24%), Positives = 99/288 (34%), Gaps = 43/288 (14%)
Query: 1024 PATPSSHPTSPPPA----------------SPPPTPGITRKEEAPENVVEKKDLELEKEA 1067
P P PT P A P PG + E P + K ++LE +
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKP---LGKAGVQLEPQL 430
Query: 1068 PSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALS 1127
+P +PP PP P + +A L+P PE L S
Sbjct: 431 EAPLNEEMPLLPPPEESPLSPPPEESP------TSPPPEASRLSPP-------PEELPAS 477
Query: 1128 PEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAM 1187
P + + LS PL PEE PL+ + ++E P PP ESP P PA E
Sbjct: 478 PLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLS-PPEESP-PSPALETP 535
Query: 1188 ATPSPAGGCGGGLLEAQALSATGQS--CAEPSECPDFVEGPE------PRVDSPGRTEPC 1239
+P P E LS + + P E PE P +SP P
Sbjct: 536 LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE 595
Query: 1240 TAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSES 1287
+ L + +P + +E P+ P + PE+ P ES
Sbjct: 596 ASRLFPPFEESPLS-PPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642
Score = 50.4 bits (119), Expect = 3e-05
Identities = 86/390 (22%), Positives = 135/390 (34%), Gaps = 64/390 (16%)
Query: 1028 SSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIP---PRYPF 1084
S P P + P P ++ + E P + ++L L + P + + P P+
Sbjct: 771 SPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEE 830
Query: 1085 QALPPHYGRPY-----------PFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPI 1133
L P P P L +P + + P+ P PE L L P
Sbjct: 831 SHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK-PPEEPGQCPAPEELPLFPPPGEP 889
Query: 1134 RLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEG--------PTELPPLESPLPLPAAE 1185
LSP + EP P E PL+ + + E P LPP SP+ AA
Sbjct: 890 SLSPL-LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948
Query: 1186 AMATP--------------SPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVD 1231
+P P +LE +C +P P + P P
Sbjct: 949 PALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSP 1008
Query: 1232 ----SPGRTEPCTAALDLGVQ--LTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPS 1285
SP EP +Q L P+ ++ P +P++VP P + +V
Sbjct: 1009 VGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPS----PLSPIGKVVGV 1064
Query: 1286 ESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLED-------- 1337
+ L + + E +CP+LEP P L S + P+L+D
Sbjct: 1065 SDEAELHEMETE-KVSEPECPALEPSATSP-LPSPMGDLSCPAPSPAPALDDFSGLGEDT 1122
Query: 1338 -PLAGMNALAAAAELPQARPLPSPGAAGAQ 1366
PL G++A + Q P +PG+ ++
Sbjct: 1123 APLDGIDAPGS-----QPEPGQTPGSLASE 1147
Score = 48.1 bits (113), Expect = 1e-04
Identities = 115/473 (24%), Positives = 158/473 (33%), Gaps = 102/473 (21%)
Query: 964 ATAGPGLLPRKP----------PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLE 1013
+T P L PR P PG+ G A +SPPP + +K + +
Sbjct: 2239 STPDPFLKPRCPSLDNLAVPESPGVGGGKASE--PLLSPPPFGESRKALEVKKEELGASS 2296
Query: 1014 DVSKPPAYAYPATPSSHP-------TSPPPASPPPTPGITRKEEAPENVVEKKDLELEKE 1066
PP + +PSS +P P TP ++ E + L L +
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEP------QSPGLGLRPQ 2350
Query: 1067 APSPFQALFSDIPPRYPFQALPPHYGRPY---PFLLQPTAAADADGLA-PDVPLPADGPE 1122
P P QAL + PP +P P Y PY P +P A P LP+D
Sbjct: 2351 EPPPAQAL-APSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFS 2409
Query: 1123 RLALSPEDK--------PIRLS-----PSKITEPLREGPEEEPLAEREVKAEVEDMDEGP 1169
R+ SP+ + P LS PS +T P + P+ P + + + D P
Sbjct: 2410 RVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT-PRFQSPD--PYSRPPSRPQSRD-PFAP 2465
Query: 1170 TELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPS-ECPDFVEGP-- 1226
PP P P A +A + + G GG A A PS + P+FV P
Sbjct: 2466 LHKPPRPQP-PEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGT 2524
Query: 1227 -----------------------EPRVDSPGRTEPCTAALDLGV-------QLTPETLVE 1256
+P V PG P G Q T T+
Sbjct: 2525 GAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVAT 2584
Query: 1257 AKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPV 1316
P P+ GL+ + P P PA +G P L A
Sbjct: 2585 GNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPP--------PAPDGSLPYLS-HGASQR 2635
Query: 1317 LGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALE 1369
G T +E+ EDP GM + A AELP + PG +G E
Sbjct: 2636 SGITSPVEKR---------EDPGTGMGSSLATAELPGTQ---DPGMSGLSQTE 2676
Score = 45.1 bits (105), Expect = 0.001
Identities = 113/479 (23%), Positives = 171/479 (35%), Gaps = 68/479 (14%)
Query: 897 QQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLE 956
QQ Q QQ +QQ+ LQQQ Q +LQ+ Q +Q++ + Q+ + + +++ + GL
Sbjct: 3921 QQQQQLQQQQLQQQQQQQQLQQQQQQ--QLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLL 3978
Query: 957 AAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRA-SPVAALKAKVIQKLEDV 1015
+ L+ ++ +A GP G K + SP A P L K E
Sbjct: 3979 NQSRTLLSPQ-----QQQQQQVALGP-GMPAKPLQHFSSPGALGPTLLLTGK-----EQN 4027
Query: 1016 SKPPAYAYPAT--PSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQA 1073
+ PA + AT PS+H P P T E ++ L L + P P +
Sbjct: 4028 TVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPS 4087
Query: 1074 LFSDIPP-RYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKP 1132
PP R P Q + LL L A L P
Sbjct: 4088 SLQLQPPLRLPGQQ------QQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQP-SVS 4140
Query: 1133 IRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSP 1192
+ P +T+ L GP ++P+ ER ++ + P P L+S LP M T
Sbjct: 4141 LGDQPGSMTQNLL-GP-QQPMLERPMQNNTG--PQPPKPGPVLQSGQGLPGVGIMPTV-- 4194
Query: 1193 AGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPE 1252
G L AQ + P+ R SP + + A L +Q +
Sbjct: 4195 ------GQLRAQLQGV-------------LAKNPQLRHLSPQQQQQLQALL---MQRQLQ 4232
Query: 1253 TLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPS-------ESQPTLEMSDCDVPAGEGQC 1305
++ P P P + P +GL P ++ P E+ P G +
Sbjct: 4233 QSQAVRQTP---PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRL 4289
Query: 1306 PSLEPQEAV---PVLGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARP-LPSP 1360
P+ P A+ PVLG SS Q + + L A+LP P P P
Sbjct: 4290 PA--PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346
Score = 44.3 bits (103), Expect = 0.002
Identities = 74/352 (21%), Positives = 109/352 (30%), Gaps = 62/352 (17%)
Query: 2359 STPLALEPSSTPGSKKSPPEPVDK-------------------RAKAPKARPAPPQPSPA 2399
S P P + P S SP P+ K + P P+ P P+
Sbjct: 1037 SPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPS 1096
Query: 2400 PPAFTSCPAPEPFAELP---APATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGE 2456
P SCPAP P L AP I P ++P+P + + S KG
Sbjct: 1097 PMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSP---- 1152
Query: 2457 EAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAP 2516
V LD E + + P+ + G P EP+AP
Sbjct: 1153 -----VLLDPEELAPVTPMEVY----------------PECKQTAGQGSPCEEQEEPRAP 1191
Query: 2517 W----PKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSS--GSSSS 2570
P D+ E ++ G+ + G+ + E S S G S+
Sbjct: 1192 VAPTPPTLIKSDIVNE----ISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTD 1247
Query: 2571 SSSSSSSGSE---TEGEEEGDKN--GDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSS 2625
S + GS T+ E D + D G G R S + S SSS
Sbjct: 1248 VSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSS 1307
Query: 2626 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDS 2677
+ + S++SS + + SS S D+D+
Sbjct: 1308 FPGRRRPRGGAHGGRGRGRARLKSTASSIETLVVADIDSSPSKEEEEEDDDT 1359
Score = 43.9 bits (102), Expect = 0.002
Identities = 44/153 (28%), Positives = 64/153 (41%), Gaps = 31/153 (20%)
Query: 2322 SEEPGAKARG-RGRKPSA-----------------KAKGDRAATLEEGNPTDEVPST-PL 2362
+E PG K +G G+ P K++ D + L++ +P E P+
Sbjct: 4835 AEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSY 4894
Query: 2363 ALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPA-PPAFTSCPAP-EPFAELPAPAT 2420
S+ + S P P + P P+P PSPA PP P EP AE P P+
Sbjct: 4895 TYNVSNLDVRQLSAPPPEE-----PSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPS- 4948
Query: 2421 SLAPAPLITMP-ATRPKPKKARAAEESGAKGPR 2452
P PL + P + RPKP+ E ++ PR
Sbjct: 4949 ---PLPLASSPESARPKPRARPPEEGEDSRPPR 4978
Score = 43.1 bits (100), Expect = 0.004
Identities = 209/949 (22%), Positives = 303/949 (31%), Gaps = 181/949 (19%)
Query: 173 PGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGR---GGEPPPLFGKKDPRARG 229
PG+L S P+A S PA S+S DG K AG P LF K P+
Sbjct: 2110 PGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPA 2169
Query: 230 EEASGPRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAG 289
+ S + L E R PP SP G
Sbjct: 2170 QVPS--QDPFGLAPAYPLEPRFPTAPPTYPPYPSP-----------------------TG 2204
Query: 290 DVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGP--RP-CPS----PLPPPPAPP 342
P ++ + R GA + R + P P +P CPS +P P
Sbjct: 2205 APAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG 2264
Query: 343 KGPPAPPAATPAGV---YTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARA 399
G + P +P + E +P++ P F + P +
Sbjct: 2265 GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSP--------SSGTHL 2316
Query: 400 REREAGRPGVLQAPPGSPR-----PLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASP 454
E P V +AP +PR P GLR + P P P + +
Sbjct: 2317 GGLELKTPDVFKAPL-TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYT 2375
Query: 455 DPRAYVPAKELLKPEADPRPCERAPRG---------PAGPAAQQAAKL------FGLEPG 499
DP A P +P C PR PA P +Q +++ E
Sbjct: 2376 DPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAF 2435
Query: 500 RPPPTGPEHKWK-PFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAVL 558
P P P + P+ A H R + A S L G
Sbjct: 2436 CPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGF- 2494
Query: 559 PRSAATCGRPVADMHSA-----------AHGSGEASAMQSLIKYSGSFARDAVAVRPG-- 605
AA P ++H+ + G+G S ++++ A +++P
Sbjct: 2495 --PAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP 2552
Query: 606 GCGKKSPFGGLGTMKPEPA---PTSAGASRAQARLPHSG---GPAAGG-GRQLKRDPERP 658
G P G P P P S + A SG GP++G G P RP
Sbjct: 2553 QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP 2612
Query: 659 ESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLSLSNVKG 718
S + GI V +++D G +G L E L +
Sbjct: 2613 PSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTG--MGSSLATAE----LPGTQD 2666
Query: 719 HGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLM 778
G + + + + +RL +E L+R+ + L + T+ A G
Sbjct: 2667 PGMSGLSQTELEKQRQRQRL--------RELLIRQQIQRNTLRQEKETAAAAAG------ 2712
Query: 779 VTGGPALAGSGRWSADPAAHLATHPWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPG 838
A+ G W A+P++ ++ A GL PPS G P
Sbjct: 2713 -----AVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGL-PPSKLSG------PI 2760
Query: 839 LG-GSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSPLHHAQ 897
LG GS PS + R P PS + +L+ + + PG PL Q
Sbjct: 2761 LGPGSFPSDDRLSRPPPPAT----PSSMDVNSRQLVGGSQA--FYQRAPYPGSLPLQQQQ 2814
Query: 898 QLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEA 957
Q QL+ QQ Q AA ++ SA+ G + G +A
Sbjct: 2815 Q-QLWQQQ-----------QATAATSMRFAMSARFPST-------------PGPELGRQA 2849
Query: 958 AGK--AGLATAGPGLLPRKP-PGLAA---------------GPAGTYGKAVSPPPSPRAS 999
G AG++T PG P +P PG A GP GT PP PR
Sbjct: 2850 LGSPLAGISTRLPG--PGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFY 2907
Query: 1000 PVA----ALKAKVIQKLEDVSKPP--AYAYPATPSSHPTSPPPASPPPT 1042
PV+ L + ++ L PP A PA ++ P P + PT
Sbjct: 2908 PVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPT 2956
Score = 41.2 bits (95), Expect = 0.015
Identities = 91/456 (19%), Positives = 149/456 (32%), Gaps = 62/456 (13%)
Query: 2353 PTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPF 2412
P +PS P + P+S P S+ S P+ R + +A PSP P F S P+P+
Sbjct: 2399 PPRSLPSDPFSRVPAS-PQSQSSSQSPLTPRPLSAEAF----CPSPVTPRFQS---PDPY 2450
Query: 2413 AELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEA-ELLVKLDHEGVTS 2471
+ P+ S P + P P+P+ A ++G+ G + G
Sbjct: 2451 SRPPSRPQSRDPFAPLHKP---PRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELH 2507
Query: 2472 PKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPK---ATDGDLAQE 2528
K + +R PG G + S + ++P A G K P P+ +
Sbjct: 2508 AKVPSGQPPNFVR-SPGTGAFVGTPSPMRF-TFPQAVGEPSLKPPVPQPGLPPPHGINSH 2565
Query: 2529 PGPGLT---------------FEDSGNPKSPDK-AQAEQDGAEESESSSSSSSGSSSSSS 2572
GPG T F SG+P P + E G S + S
Sbjct: 2566 FGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSL 2625
Query: 2573 SSSSSGSETEG--EEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSS----- 2625
S G+ +K D G G G +A P S S +
Sbjct: 2626 PYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQR 2685
Query: 2626 ----------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
++ ++++++ + S + SS + S + + T D+
Sbjct: 2686 LRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDK 2745
Query: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKK----------TPAPQ 2725
S P GP + + + ++ A PS+ + AP
Sbjct: 2746 SSLVGLPPSKLSGPILGPGSFPS-DDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPY 2804
Query: 2726 P-QAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTT 2760
P P Q Q L + QA A + + P+T
Sbjct: 2805 PGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPST 2840
Score = 40.8 bits (94), Expect = 0.020
Identities = 54/216 (25%), Positives = 78/216 (36%), Gaps = 26/216 (12%)
Query: 968 PGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATP 1027
P +LP P P G + P P+ SP+ L + PP+ P P
Sbjct: 998 PMILPPSP----GSPVGPASPILMEPLPPQCSPLLQ------HSLVPQNSPPSQCSP--P 1045
Query: 1028 SSHPTSPPPASP-PPTPGITRKEEA----PENVVEKKDLELEKEAPSPFQALFSDI--PP 1080
+ + P P SP G++ + E E V E + LE A SP + D+ P
Sbjct: 1046 ALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPA 1105
Query: 1081 RYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKI 1140
P AL G L + TA D P P P LA + P+ L P ++
Sbjct: 1106 PSPAPALDDFSG-----LGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEEL 1160
Query: 1141 --TEPLREGPEEEPLAEREVKAEVEDMDEGPTELPP 1174
P+ PE + A + E ++ P P
Sbjct: 1161 APVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTP 1196
Score = 40.4 bits (93), Expect = 0.026
Identities = 67/265 (25%), Positives = 92/265 (34%), Gaps = 68/265 (25%)
Query: 917 QQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPP 976
QQQ QAL +QR Q Q + G + + GL P L P
Sbjct: 4218 QQQQLQALLMQRQLQ--------QSQAVRQTPPYQEPGTQTSPLQGLLGCQPQL--GGFP 4267
Query: 977 GLAAGPAGTYGKAVSPPPSPRA-SPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPP 1035
G GP G P PR +P AL P HPT PP
Sbjct: 4268 GPQTGPLQELGAGPRPQGPPRLPAPPGALSTG----------------PVLGPVHPT-PP 4310
Query: 1036 PASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSD--IPPRYPFQALPPHYG- 1092
P+SP ++ + + PSP L ++ +PP +P P G
Sbjct: 4311 PSSP-------------------QEPKRPSQLPSPSSQLPTEAQLPPTHP--GTPKPQGP 4349
Query: 1093 --RPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITE-------- 1142
P P + P AA AD L P D P+ LA + + + L P + +
Sbjct: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPE 4409
Query: 1143 ----PLREGPEEEP--LAEREVKAE 1161
+++ P EEP L + VK E
Sbjct: 4410 ASQLSIKQEPREEPCALGAQSVKRE 4434
Score = 39.3 bits (90), Expect = 0.059
Identities = 99/421 (23%), Positives = 129/421 (30%), Gaps = 57/421 (13%)
Query: 2372 SKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMP 2431
S+ SPPEP D P A Q P TS EP L A L A + P
Sbjct: 370 SRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEP-GPLQCEAKPLGKAGVQLEP 428
Query: 2432 ATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGG 2491
+A EE P P E L E TSP EA L P
Sbjct: 429 QL-----EAPLNEEM----PLLPPPEESPLSPPPEESPTSP----PPEASRLSPPPE--- 472
Query: 2492 WQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQ 2551
+ P S L + P +P P+ + E P E+S P SP +
Sbjct: 473 -ELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES--PLSPPEESPPS 529
Query: 2552 DGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAAS 2611
E S +S S S S E +
Sbjct: 530 PALETPLSPPPEASPLSPPFEESPLSPPPEE----------------------LPTSPPP 567
Query: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
AS S S S S S +S S S S S +S S
Sbjct: 568 EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS 627
Query: 2672 TTDEDSSCSSDDEAAP-APTAGPSAQAALP-----TKATKQAGKARPSAHSPGKKTPAPQ 2725
EDS S E +P +P S + LP + +++ + P SP P
Sbjct: 628 PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS 687
Query: 2726 PQAPPPQ--PT------QPLQPKAQAGAKSRPKKREG-VHLPTTKELAKRQRLPSVENRP 2776
+PPP+ PT P P + S P + + LP +L R P + RP
Sbjct: 688 RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747
Query: 2777 K 2777
+
Sbjct: 748 E 748
Score = 37.7 bits (86), Expect = 0.17
Identities = 51/188 (27%), Positives = 63/188 (33%), Gaps = 23/188 (12%)
Query: 324 LLPGPRPCPSPLPPPPAPPKGPP------APPAATPAGVYTVFREQGREHRVVAPTFVPS 377
LLP P P PP +P PP PP PA R +P P
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLE-ESPLSPPP 498
Query: 378 VEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLK 437
E+ P S ++ E P P SP P P + S +
Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL---- 554
Query: 438 RPPPADAPTVRATRASPDPRAYVPAKELLKPEADPR--PCERAPRGPAGPAAQQAAKLFG 495
PPP + PT SP P A ++ PE P P E +P P P A + F
Sbjct: 555 SPPPEELPT------SPPPEA---SRLSPPPEESPMSPPPEESPMSPP-PEASRLFPPFE 604
Query: 496 LEPGRPPP 503
P PPP
Sbjct: 605 ESPLSPPP 612
Score = 37.7 bits (86), Expect = 0.17
Identities = 124/536 (23%), Positives = 171/536 (31%), Gaps = 84/536 (15%)
Query: 8 PQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAFL 67
P+ S PPP ++ R+ LPAS LP L + + L P P E+ L
Sbjct: 453 PEESPTSPPP--------EASRLSPPPE-ELPASPLPEALHLSRPLEESPLSPPPEESPL 503
Query: 68 GSFVASGMGPSASSHGSPV---PL-PSDLSFRSP---TPSNLPMVQLWAAHAHEGFSHLP 120
P SS SP+ PL P + S SP TP + P A+ F P
Sbjct: 504 SP-------PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPE---ASPLSPPFEESP 553
Query: 121 SGLYPSYL------HLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPG 174
P L + L PP SP+ P ++ P + P +P
Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPEESPM-----SPPPEESPMSPPPEASRLFPPFEESPL 608
Query: 175 SLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASG 234
S P P + S P + PPP + P S
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS----PPPEVSRLSPLPVVSRLSP 664
Query: 235 PRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTK-----NAALQPSVLTMCNGGAG 289
P L+ PP A RLSP +S T + A P ++ +
Sbjct: 665 PPEESPLSPPPE---ESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLE 721
Query: 290 DVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAP- 348
+ L L E + + EG L R E PRP L P P P P
Sbjct: 722 ESPLLPLPEEP------QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE 775
Query: 349 ----------PAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERP--------GPIQI 390
P +P Q E + T P + E P +
Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835
Query: 391 ASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRAT 450
S+ R E+ L+ PP SPRP PE + + PPP + P++
Sbjct: 836 QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGE-PSLSPL 894
Query: 451 RASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGP 506
P E +P P P E P P+G + + +L +P PPP P
Sbjct: 895 LGEP------ALSEPGEPPLSPLP-EELPLSPSGEPS-LSPQLMPPDP-LPPPLSP 941
Score = 37.0 bits (84), Expect = 0.29
Identities = 95/442 (21%), Positives = 148/442 (33%), Gaps = 53/442 (11%)
Query: 2351 GNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKAR-----PAPPQPSPAPPAFTS 2405
G+ T P P L+ + P K ++ + +AP P P + +PP S
Sbjct: 399 GHVTSMQPKEPGPLQCEAKPLGKAGVQ--LEPQLEAPLNEEMPLLPPPEESPLSPPPEES 456
Query: 2406 CPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLD 2465
+P P A +P PA + +P + + P P E+ L+
Sbjct: 457 PTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLE 516
Query: 2466 HEGVTSPKSKKAKEAL--LLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDG 2523
++ P+ AL L P A P L S PP P +P P+A+
Sbjct: 517 ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL-SPPP---EELPTSPPPEAS-- 570
Query: 2524 DLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEG 2583
P P E+S P SP ++ E+ S S S S
Sbjct: 571 --RLSPPP----EES--PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP--- 619
Query: 2584 EEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS--S 2641
+SR + P S S S S S S S
Sbjct: 620 -------------------PPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660
Query: 2642 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPT 2701
S S S S +S +S S EDS S E +PA + +LP
Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720
Query: 2702 KATKQAGKARPSAHSPGKKTP--APQPQAP--PPQPTQP-LQPKAQAGAKS-RPKKREGV 2755
+ + P + P +P+P+ P P+P +P L P+A+ S +P++
Sbjct: 721 EESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLC 780
Query: 2756 HLPTTKELAKRQRLPSVENRPK 2777
+P L+ + P + +P+
Sbjct: 781 AVPEEPHLSPQAEGPHLSPQPE 802
Score = 36.2 bits (82), Expect = 0.50
Identities = 88/416 (21%), Positives = 129/416 (31%), Gaps = 78/416 (18%)
Query: 2312 GEGKDGGTAGSEEPGAKARGRGRKP----SAKAKGDRAATLEEGNP-TDEVPSTPLA--L 2364
GE + EE GA + G + + G LE P + P TP A +
Sbjct: 2279 GESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQV 2338
Query: 2365 EPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELP-------- 2416
EP S PG P EP P A+ P P P F +P+A+ P
Sbjct: 2339 EPQS-PGLGLRPQEP-------PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP 2390
Query: 2417 -------APATSLAPAPLITMPAT-----------RPKPKKARA-----------AEESG 2447
P SL P +PA+ P+P A A + +
Sbjct: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450
Query: 2448 AKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPA 2507
++ P RP + + L P K L GAGG+ P +L PA
Sbjct: 2451 SRPPSRP-QSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGF--PAAL-------PA 2500
Query: 2508 AGSSEPKAPWPKATDGDLAQEPGPG----------LTF-----EDSGNPKSPDKAQAEQD 2552
+ E A P + + PG G TF E S P P
Sbjct: 2501 GPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPH 2560
Query: 2553 GAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASP 2612
G + S++ + ++ G G +G G + G + S P
Sbjct: 2561 GINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG-ESYGLSPLRPPSVLPPP 2619
Query: 2613 ASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668
A S S +S S +S + SS +++ + S S +
Sbjct: 2620 APDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQT 2675
Score = 35.8 bits (81), Expect = 0.65
Identities = 60/247 (24%), Positives = 91/247 (36%), Gaps = 33/247 (13%)
Query: 2348 LEEGNPTDEVPSTPLALEPSSTPGS---KKSPPEPVDKRAKAP--KARPAPPQPSPAPPA 2402
L P +E P +P P +P S + SP P+++ +P ++ P+P +P P
Sbjct: 483 LHLSRPLEESPLSP---PPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPP 539
Query: 2403 FTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAA---EES-----GAKGPRRP 2454
+ P PF E P L+P P +P T P P+ +R + EES + P P
Sbjct: 540 PEASPLSPPFEESP-----LSPPP-EELP-TSPPPEASRLSPPPEESPMSPPPEESPMSP 592
Query: 2455 GEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPK 2514
EA L E SP +++ L P A P + P + S P
Sbjct: 593 PPEASRLFPPFEESPLSPPPEESP----LSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648
Query: 2515 -----APWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSS 2569
+P P + E P L+ +P SP + E +S S +
Sbjct: 649 EVSRLSPLPVVSRLSPPPEESP-LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA 707
Query: 2570 SSSSSSS 2576
S S
Sbjct: 708 SPPPEDS 714
Score = 35.8 bits (81), Expect = 0.65
Identities = 50/203 (24%), Positives = 73/203 (35%), Gaps = 29/203 (14%)
Query: 1774 GPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEE 1833
G LT+ G+A R L P R+Q L EA S+ S+ D+ + D +
Sbjct: 1589 GVWLTETGMALLRNLTMSPLHKRRQRRGRLGLPGEAGLEGSEPSDALGPDDKKDGDLDTD 1648
Query: 1834 EELEEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAK 1893
E L+ E GG + + P SP V P + E
Sbjct: 1649 ELLKGE----GGVEHMECEIKLEGP------------------VSPDVEPGKE--ETEES 1684
Query: 1894 QKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAA--PTPGAR 1951
+K ++K R + G S + K+ PA G G+P + A P GA
Sbjct: 1685 KKRKRKPYRPGIGGFMVRQRKSHTRT---KKGPAAQAEVLSGDGQPDEVIPADLPAEGAV 1741
Query: 1952 GPDPSSPDKAKLAVEKGRKARKL 1974
+ D+ K +GRK KL
Sbjct: 1742 EQSLAEGDEKKKQQRRGRKKSKL 1764
Score = 35.8 bits (81), Expect = 0.65
Identities = 30/82 (36%), Positives = 34/82 (41%), Gaps = 26/82 (31%)
Query: 1111 APDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPT 1170
AP P+ P LA SP P TEPL E P E PLAE
Sbjct: 4908 APPPEEPSPPPSPLAPSPASPP--------TEPLVELPTE-PLAE--------------- 4943
Query: 1171 ELPPLESPLPLPAAEAMATPSP 1192
PP+ SPLPL ++ A P P
Sbjct: 4944 --PPVPSPLPLASSPESARPKP 4963
Score = 34.7 bits (78), Expect = 1.4
Identities = 89/439 (20%), Positives = 133/439 (30%), Gaps = 51/439 (11%)
Query: 2355 DEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAE 2414
+E +P + EP +P ++S P + P P P +P P CPAPE
Sbjct: 829 EESHLSPQSEEPCLSPRPEESHLSP---ELEKPPLSPRPEKPPEEPG---QCPAPEELPL 882
Query: 2415 LPAPATSLAPAPLITMPATRP--KPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSP 2472
P P + +PL+ PA +P + EE P +L+ SP
Sbjct: 883 FPPPGEP-SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP 941
Query: 2473 KSKKAKEALL-----LREDPGAGGWQEPKSLLSLG------SYPPAAGSSEPKAPWPKAT 2521
A L L GA G +P+S L+ S PP A ++P+ P
Sbjct: 942 IITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMIL 1001
Query: 2522 DGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSS---SSSSSSSSSG 2578
GP P P + Q S S S + S S S G
Sbjct: 1002 PPSPGSPVGPASPI--LMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIG 1059
Query: 2579 SETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSS 2638
+E + + C A A SP S S + S + + S
Sbjct: 1060 KVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLG 1119
Query: 2639 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----------------------STTDED 2676
++ + S + S +S S T +
Sbjct: 1120 EDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQG 1179
Query: 2677 SSCSSDDE-AAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQ 2735
S C +E AP P+ + + SA PG + P +P P+
Sbjct: 1180 SPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSE---PLLGSPDPEGGG 1236
Query: 2736 PLQPKAQAGAKSRPKKREG 2754
L + P + EG
Sbjct: 1237 SLSMELGVSTDVSPARDEG 1255
Score = 34.7 bits (78), Expect = 1.4
Identities = 52/203 (25%), Positives = 68/203 (33%), Gaps = 44/203 (21%)
Query: 326 PGPRPCPSPLPPPPAPPKGP-------PAPPAATPAGVYTVFREQGREHRVVAPTFVPSV 378
P P P P LPP P P GP P PP +P +++ + + P SV
Sbjct: 993 PEPVP-PMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSV 1051
Query: 379 EAFDERPGPIQIASQARDARARERE-------------AGRP-----GVLQAPPGSPRP- 419
+ G + S + E E A P G L P SP P
Sbjct: 1052 PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPA 1111
Query: 420 LDRPEGLREKNSVIRSL----KRPPPADAPTVRAT--RASP---DPRAYVPA------KE 464
LD GL E + + + +P P P A+ + SP DP P E
Sbjct: 1112 LDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPE 1171
Query: 465 LLKPEADPRPCE--RAPRGPAGP 485
+ PCE PR P P
Sbjct: 1172 CKQTAGQGSPCEEQEEPRAPVAP 1194
Score = 34.3 bits (77), Expect = 1.9
Identities = 59/260 (22%), Positives = 86/260 (33%), Gaps = 33/260 (12%)
Query: 1045 ITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAA 1104
I + ++ E+ + K+ + + AL IPP+ PP P F+ PT
Sbjct: 2073 INKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTP 2132
Query: 1105 A----DADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKA 1160
A ADG GP+ SP + ++L P + + P ++P
Sbjct: 2133 AGLSTSADGFLKPPAGSVPGPD----SPGELFLKLPP----QVPAQVPSQDPFGLAPAYP 2184
Query: 1161 EVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECP 1220
P PP SP PA M S G G G+ P P
Sbjct: 2185 LEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAG----------QPGEFHTTPPGTP 2234
Query: 1221 DFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEA-----VP 1275
+P P C + +L V +P EP+ P P E+ V
Sbjct: 2235 RH----QPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSP--PPFGESRKALEVK 2288
Query: 1276 EEGLAQVAPSESQPTLEMSD 1295
+E L +PS P L D
Sbjct: 2289 KEELGASSPSYGPPNLGFVD 2308
Score = 34.3 bits (77), Expect = 1.9
Identities = 48/207 (23%), Positives = 79/207 (38%), Gaps = 23/207 (11%)
Query: 320 RTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGV------------YTVFREQGREH 367
R T LPG L PP PP G TP G+ + ++Q ++H
Sbjct: 3626 RLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQH 3685
Query: 368 RVVAPTFV-PSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGL 426
A + PS F PG + + S D+R + + + + +
Sbjct: 3686 SGGAGSLAGPSGGFF---PGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQ 3742
Query: 427 REKNSVIRSLKRPPPADAPTVRATRA-SPDPRAYVPAKE---LLKPEADPRPCERAPRGP 482
++++ + + + P V+ +A P P+ +P LL + P+P + P+G
Sbjct: 3743 QQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP-PQGPQGM 3801
Query: 483 AGPAAQQAAKLFGLEPGRPPPTGPEHK 509
GPA Q A L PG P GP +
Sbjct: 3802 LGPA--QVAVLQQQHPGALGPQGPHRQ 3826
Score = 34.3 bits (77), Expect = 1.9
Identities = 40/164 (24%), Positives = 60/164 (36%), Gaps = 25/164 (15%)
Query: 2358 PSTPLALEPSSTPGSKKSP--PEPVDKRAKAPKARPAPPQPSPAPPAFTSCPA--PEPFA 2413
P T E + P + P P P + P P P P P+ P P+ P P +
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328
Query: 2414 ELPA--------PATSLAPAPLITMPATRPKPKKARAAEESGAKG------------PRR 2453
+LP P T P + P R P A+ A+ +KG ++
Sbjct: 4329 QLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQK 4388
Query: 2454 PGEEAELLVKLDH-EGVTSPKSKKAKEALLLREDPGAGGWQEPK 2496
P + + + LD G P++ + RE+P A G Q K
Sbjct: 4389 PEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVK 4432
Score = 33.9 bits (76), Expect = 2.5
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 9/86 (10%)
Query: 332 PSPLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIA 391
P PLPPP +P APPA +P G + +P P +E PI
Sbjct: 932 PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILET------PI--- 982
Query: 392 SQARDARAREREAGRPGVLQAPPGSP 417
S +A + E P +L PGSP
Sbjct: 983 SPPPEANCTDPEPVPPMILPPSPGSP 1008
Score = 33.5 bits (75), Expect = 3.2
Identities = 81/317 (25%), Positives = 112/317 (35%), Gaps = 77/317 (24%)
Query: 962 GLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAY 1021
GLA A P L PR P A P TY SP +P P+ ++ +P +
Sbjct: 2178 GLAPAYP-LEPRFP---TAPP--TYPPYPSPTGAPAQPPMLGASSR-----PGAGQPGEF 2226
Query: 1022 --AYPATPSSHPTSPPP-----------ASPPPTPGITRKEEA------PENVVEKKDLE 1062
P TP P++P P + P +PG+ + + P +K LE
Sbjct: 2227 HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALE 2286
Query: 1063 LEKE---APSPFQALFSDIPPRYPFQALP---PHYG-----RPYPFL--LQPTAA----- 1104
++KE A SP S PP F P H G P F L P A+
Sbjct: 2287 VKKEELGASSP-----SYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341
Query: 1105 ADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGP----EEEPLAEREVKA 1160
+ GL P P PA + LA SP P P T+P + P + P E
Sbjct: 2342 SPGLGLRPQEPPPA---QALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL 2398
Query: 1161 EVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECP 1220
+ P P SP ++++ TP P L A+A PS
Sbjct: 2399 PPRSLPSDPFSRVP-ASPQSQSSSQSPLTPRP--------LSAEAFC--------PSPVT 2441
Query: 1221 DFVEGPEPRVDSPGRTE 1237
+ P+P P R +
Sbjct: 2442 PRFQSPDPYSRPPSRPQ 2458
Score = 33.5 bits (75), Expect = 3.2
Identities = 64/297 (21%), Positives = 92/297 (30%), Gaps = 53/297 (17%)
Query: 2469 VTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQE 2528
V S K +EALL +PG G +E PPAA +SEP+ + E
Sbjct: 3073 VESANEKAEREALLRGVEPGPLGPEERP--------PPAADASEPRL-------ASVLPE 3117
Query: 2529 PGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGD 2588
P + E+ G SP + E + +++S G S S +
Sbjct: 3118 VKPKV--EEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDT--------- 3166
Query: 2589 KNGDGGCGTGGRNCSAASSRAA----------SPASSSSSSSSSSSSSSSSSSSSSSSSS 2638
+ G G + G AS A SP S SS S + +
Sbjct: 3167 RMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGP 3226
Query: 2639 SSSSSSSSSSSSSSSSSS------------SSSSSSSSSSSSSSSTTDEDSSCSSDDEAA 2686
++S SS +S S+ +
Sbjct: 3227 AASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLL 3286
Query: 2687 PAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQA 2743
AP GP+ +LP + + + S G A Q PQP P QP A A
Sbjct: 3287 SAP--GPAQAMSLPHEGSSPSLAGSQQQLSLGL---AGARQPGLPQPLMPTQPPAHA 3338
Score = 33.1 bits (74), Expect = 4.2
Identities = 30/99 (30%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 413 PPGSPRPLDRPEGLREKNSVIRSLK-RPPPADAPTVRATRASPDPRAYVPAKELLKP--E 469
P G PR L P G V+ + PPP+ + P P + +P + L P
Sbjct: 4283 PQGPPR-LPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHP 4341
Query: 470 ADPR---PCERAPRGPAGPAAQQAAKLF---GLEPGRPP 502
P+ P P G PAA Q A GL P PP
Sbjct: 4342 GTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
Score = 32.7 bits (73), Expect = 5.5
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 14/105 (13%)
Query: 1024 PATPSSHPTSPPPA-SPPPTPGITRKEEA---PENVVEKKDLELEKEAPSPFQALFSDIP 1079
P PSS P +PPP+ G+T EE P++ +D E S ++L D+
Sbjct: 4620 PTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSL--DLL 4677
Query: 1080 PRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERL 1124
P PPH +D D +PD +PA PE +
Sbjct: 4678 AALP---TPPHNQTE-----DVRMESDEDSDSPDSIVPASSPESI 4714
Score = 32.3 bits (72), Expect = 7.2
Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 19/109 (17%)
Query: 1850 GARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTE 1909
G +E+ L ++G L +F A LP T+ L ++ L KQ++ E T+
Sbjct: 4839 GGKEKGLEGKSPDTGPDWLKQFDA-VLPGYTLKSQLDILSL-LKQESPAPEPP-----TQ 4891
Query: 1910 FEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSP 1958
YT + S + VR+ L P P +P P P P+SP
Sbjct: 4892 HSYTYNVSNLDVRQ------------LSAPPPEEPSPPPSPLAPSPASP 4928
Score = 32.3 bits (72), Expect = 7.2
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 13/94 (13%)
Query: 1145 REGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQ 1204
+E P EP + V ++D PP E P P P+ A PSPA L+E
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLA---PSPASPPTEPLVELP 4937
Query: 1205 ALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEP 1238
+ AEP V P P SP P
Sbjct: 4938 T-----EPLAEPP-----VPSPLPLASSPESARP 4961
Score = 32.0 bits (71), Expect = 9.4
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 470 ADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFEL 515
A PRP + PR PA P A + G PPP+ P+ +P +L
Sbjct: 4279 AGPRP-QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQL 4323
Score = 32.0 bits (71), Expect = 9.4
Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 13/93 (13%)
Query: 337 PPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARD 396
PPP P PP+P A +PA T E V PT P E P P+ +AS
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPT-------EPLVELPT-EPLAE--PPVPSPLPLASSPES 4958
Query: 397 ARAREREAGRPGVLQAPPGSPRPLDRPEGLREK 429
AR + R RP + P L + +G+R K
Sbjct: 4959 ARPKPR--ARPPE-EGEDSRPPRLKKWKGVRWK 4988
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 79.3 bits (194), Expect = 5e-14
Identities = 131/531 (24%), Positives = 186/531 (35%), Gaps = 101/531 (19%)
Query: 2289 AEPSPALLVPSAKRR--------SRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKA 2340
A PA+ PS K S K T K+G T + P K G P +
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG-GPAMTPPSPK 1390
Query: 2341 KGDRAATLEEGNPTD---------EVPSTPLALEPSSTPGSKKSPPEPVD----KRA--- 2384
+G A +G+PT + P+TP+ E ++TP P V K+A
Sbjct: 1391 RGP-AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449
Query: 2385 KAPKARPAPPQ-------PSPAPPAFTSCPAPEPFAELPAPATSLA-PAPL--ITMPATR 2434
APK PA P P+ PP+ PAP+ A +P + A PAP+ T+PA
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509
Query: 2435 PKPKKARAAEESGAKGPRRPGEEAELLVK-----------LDHEGVTSPKSKKAKEALLL 2483
P K A S + P P A LL K L +T P KK
Sbjct: 1510 PSSPKEVPATPSSRRDPIAP--TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
Query: 2484 REDPGAGGWQE-----------------PKSLLSLGSYPPAAGSSEPK-APWPKATDGDL 2525
+E P +E PK LL PPA S PK AP P A
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELL----IPPAVTSPSPKEAPTPPAVTPP- 1622
Query: 2526 AQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEE 2585
+ E GP T G P SP + + S +S + G++ +S
Sbjct: 1623 SPEKGPA-TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK------ 1675
Query: 2586 EGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645
+ +A +PA S+ ++ + + SS++S S
Sbjct: 1676 --------------KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721
Query: 2646 SSSSSSSSSSSSSSSSSSSSSSSSSSTTD-EDSSCSSDDEAAP------APTAGPSAQAA 2698
+ + S S+ + + SS T +D+S S AP P + +
Sbjct: 1722 AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKV 1781
Query: 2699 LPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRP 2749
LP K + A PS P+P P PP Q P P + S+P
Sbjct: 1782 LP-KPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKP 1831
Score = 79.0 bits (193), Expect = 7e-14
Identities = 119/487 (24%), Positives = 160/487 (32%), Gaps = 83/487 (17%)
Query: 2281 PPDYKIQCAEPSP--ALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSA 2338
PP K A PSP A + P+A S K GG A GA PS
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPK----------GGLATPPHKGAPTTPAATPPSP 1136
Query: 2339 KAKGDRAATLEEGNPTDEVPSTPLALEPS-----STPGSKKSPPEPVDKRAKAPKARPAP 2393
K G A +G PT TP A PS +TP K +P P +PK A
Sbjct: 1137 K--GGLATPPPKGAPT-----TPAATPPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLAT 1188
Query: 2394 PQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRR 2453
P P AP + P P P L P+ AP T PA P K A S P
Sbjct: 1189 PSPKGAPTTPAATP-PSPKGGLATPSPKGAP----TTPAATPPSPKGGLATPSPKGAPTT 1243
Query: 2454 PGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEP 2513
P +P S K A PP G+ P
Sbjct: 1244 P--------------AATPPSPKGGPAT-----------------------PPPKGAPTP 1266
Query: 2514 KAPWPKATDGDLAQEPGPGLTFEDSGNPKSP--DKAQAEQDGAEESESSSSSSSGSSSSS 2571
A P + G LA P G P SP A + GA +++ S S +
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326
Query: 2572 SSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSS 2631
+ + K GT + SS+ P + SS + +++ S
Sbjct: 1327 PPPKGAPTPPAVTPPSPK------GTPTLPATTPSSK-GGPTTPSSKEGPTPPAATPSHK 1379
Query: 2632 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTA 2691
+ + S + S +S + S + ++ T E ++ S + P P
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP-PAV 1438
Query: 2692 GPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKK 2751
P + P + + G A PS+ K P PP P +P PK Q S PKK
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSS-----KGDPTLPAVTPPSPKEPPAPK-QVATSSSPKK 1492
Query: 2752 REGVHLP 2758
P
Sbjct: 1493 APATPAP 1499
Score = 78.6 bits (192), Expect = 9e-14
Identities = 108/479 (22%), Positives = 167/479 (34%), Gaps = 34/479 (7%)
Query: 2292 SPAL-LVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEE 2350
+PAL + S+ +++R T G G+ P A PS K G A +
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT-----PPSPK--GGPATPSPK 960
Query: 2351 GNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQP-------SPAPPAF 2403
PT + P +TP S K P P +PK PA P P + PP+
Sbjct: 961 WAPTPPAATPPSPKGGPATP-SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 2404 TSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVK 2463
PA PF + + + P PA P PK A + P+ L
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 2464 LDHEGVT--SPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKAT 2521
T SPK A + P A PK L+ PP G+ A P +
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT---PPHKGAPTTPAATPPSP 1136
Query: 2522 DGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSET 2581
G LA P G + P SP A + +++ ++ S G+ T
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196
Query: 2582 EGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641
+ GG T A ++ AA+P S ++ S + ++ +++
Sbjct: 1197 T-PAATPPSPKGGLATPSPK-GAPTTPAATP-----PSPKGGLATPSPKGAPTTPAATPP 1249
Query: 2642 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQ----A 2697
S ++ + + +++ S +T + + P+P GP+ A
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309
Query: 2698 ALPTKATKQAGKARPSAHSP-GKKT-PAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREG 2754
P AT + K P P G T PA P +P PT P + G + P +EG
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368
Score = 72.4 bits (176), Expect = 6e-12
Identities = 116/500 (23%), Positives = 167/500 (33%), Gaps = 40/500 (8%)
Query: 2289 AEPSPALLVPSAK--------RRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKA 2340
A +PA PS K + + T T GG A GA PS K
Sbjct: 1148 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK- 1206
Query: 2341 KGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPA--PPQPSP 2398
G A +G PT + P +TP K +P P +PK PA PP+ +P
Sbjct: 1207 -GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGPATPPPKGAP 1264
Query: 2399 APPAFTSCP-----APEPFAELPAPATSLAPAP----LITMPATRPKPKKARAAEESGAK 2449
PPA T A P P PA P+P + P P P A G+
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324
Query: 2450 GPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAG 2509
G P +P S K L GG P S G PPAA
Sbjct: 1325 GTPPPKGAPT-------PPAVTPPSPKGTPTLPATTPSSKGGPTTPSS--KEGPTPPAAT 1375
Query: 2510 SSEPKAPW---PKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSG 2566
S P P G P G + P SP KA A E + + S
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSP-KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434
Query: 2567 SSSSSSSSSSSGSETEGEEEGDKNGDG-GCGTGGRNCSAASSRAASPASSSSSSSSSSSS 2625
+ + S T + G G T + +P ++SSS +
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP 1494
Query: 2626 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEA 2685
++ + + + + SS ++ SS + +++ S + +T +
Sbjct: 1495 ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT 1554
Query: 2686 APAPT---AGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQ 2742
P+P A P+ + A T ++K+A S K P+P+ PP T P +A
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP 1614
Query: 2743 A-GAKSRPKKREGVHLPTTK 2761
A + P +G P K
Sbjct: 1615 TPPAVTPPSPEKGPATPAPK 1634
Score = 69.3 bits (168), Expect = 5e-11
Identities = 99/446 (22%), Positives = 153/446 (34%), Gaps = 41/446 (9%)
Query: 2340 AKGDRAATLEEGNPTDEVPSTPLALEPSSTPG---SKKSPPEPVDKRAKAPKARPAPPQP 2396
+K A T P+ + TP A+ P S G K P P PK PA P P
Sbjct: 846 SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905
Query: 2397 SPAPPAFTSCPAPEPFAELPAP---ATSLAPAPLITMPATRPKPKKARAAEESGAKGPRR 2453
AP + +P+ PAP S +P T PA P K A S P
Sbjct: 906 KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965
Query: 2454 PGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEP 2513
P A SPK A G PK + + P + P
Sbjct: 966 PA--ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 2514 KA-PWPKATDGDLAQEP-----GPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGS 2567
A P+PK A P P T G P +P G + S + +
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP--T 1081
Query: 2568 SSSSSSSSSSGSETEGEEEG--------DKNGDGGCGTGGRNCSAASSRAASPASSSSSS 2619
+++ S G +G + GG T A ++ AA+P S
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHK-GAPTTPAATPPSPKGGL 1140
Query: 2620 SS----SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
++ + ++ +++ S ++ + ++ +++ S ++ S + +T
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1200
Query: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAH----SPGKKTPAPQ--PQAP 2729
A P+P P+ AA P + + G A PS +P P+P+ P P
Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGPATP 1258
Query: 2730 PPQ--PTQP--LQPKAQAGAKSRPKK 2751
PP+ PT P P + G + P K
Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHK 1284
Score = 60.8 bits (146), Expect = 2e-08
Identities = 83/346 (23%), Positives = 111/346 (32%), Gaps = 25/346 (7%)
Query: 326 PGPRPCPSPLPPPPAPPKGPPAPP--AATPAGVYTVFREQGREHRVVAPTFVPSVEAFDE 383
P P+ P+P P PKG PP TP+ V F ++G P+ A +
Sbjct: 859 PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG-----------PATPAPKQ 907
Query: 384 RPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLK---RPP 440
P +S + ARA G P +P G+P P + S K PP
Sbjct: 908 APALSMTSSSPKKARATPAPKGIP-ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 441 PADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGR 500
A P+ + A+P P+ P P +P+G P A G
Sbjct: 967 AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
Query: 501 PPPTG---PEHKWKPFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAV 557
P P G P P G+ AAT + A + A S K A P A
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
Query: 558 LPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLG 617
P P + S L A A P SP GGL
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP-----PSPKGGLA 1141
Query: 618 TMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKA 663
T P+ APT+ A+ + + P G P P+ A
Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Score = 60.1 bits (144), Expect = 3e-08
Identities = 98/455 (21%), Positives = 152/455 (33%), Gaps = 49/455 (10%)
Query: 2345 AATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPA----P 2400
A LE +P P+T +T S P + APK P P
Sbjct: 647 AFPLESADPAGVAPTTAKGTSTYTTTAS----PFLEGTVSLAPKNHPVKEGTLTTLPLVP 702
Query: 2401 PAFTSCP-APEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAE 2459
A +CP AP P AP +L AP I P + P P A G K
Sbjct: 703 TASENCPVAPSP-QNTCAPLATLVLAPEI--PKSVPSPSLPPAGTPPGTKK--------- 750
Query: 2460 LLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSL--GSYPPAAGSSEPKAPW 2517
+ + H +P + KE ED GA K L+ S P S P+
Sbjct: 751 -VDGISHTSALAPVASSPKECPT--EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR 807
Query: 2518 PKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSS 2577
P G GP + +P SP E+ +S S S +++
Sbjct: 808 PPTKKGSA----GPDTPIGNLSSPVSP----------VEASFLPENSLSFQGSKDSPATT 853
Query: 2578 GSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSS 2637
S T +G + + +P+ + ++ + + + S
Sbjct: 854 HSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM 913
Query: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG-PSAQ 2696
+SSS + ++ + +S S + + +++ + + + + AP P A P +
Sbjct: 914 TSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP 973
Query: 2697 AALPTKATKQAGKARPSAHSP----GKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKR 2752
P + + P+A P G TP+P+ PP T P PK A PK
Sbjct: 974 KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP-SPKGSPAATPFPK-- 1030
Query: 2753 EGVHLPTTKELAKRQRLPSVENRPKIAAFLPARQL 2787
G P + P+ PK A PA L
Sbjct: 1031 -GASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064
Score = 56.2 bits (134), Expect = 5e-07
Identities = 92/379 (24%), Positives = 115/379 (30%), Gaps = 54/379 (14%)
Query: 951 SKRGLEAAGKAGLATAGPGLLPRKPPGLAAG---PAGTYGKAVSPPPSPRASPVAALKAK 1007
S +G A A P + P P G A P G + PPSP+ SP A K
Sbjct: 995 SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK 1054
Query: 1008 VIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEA 1067
+ P PATPS PPA+ PP+P +P+ +
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA----PMPPAATP 1110
Query: 1068 PSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALS 1127
PSP L A PPH G P P + GLA P P P A +
Sbjct: 1111 PSPKGGL-----------ATPPHKGAPTTPAATP--PSPKGGLA--TPPPKGAPTTPAAT 1155
Query: 1128 PEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAM 1187
P L+ T P + P K + P P + P +
Sbjct: 1156 PPSPKGGLA----TPPPKGAPTTPAATPPSPKGGL--ATPSPKGAPTTPAATPPSPKGGL 1209
Query: 1188 ATPSPAG----------GCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTE 1237
ATPSP G GGL A A P P GP T
Sbjct: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP---PSPKGGPATPPPKGAPTP 1266
Query: 1238 PCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPE-EGLAQVAPSESQPTLEMSDC 1296
P TP +L P P V P +G +P + PT +
Sbjct: 1267 PAA---------TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317
Query: 1297 DVPAGEGQCPSLEPQEAVP 1315
P G P P + P
Sbjct: 1318 PSPKGS---PGTPPPKGAP 1333
Score = 54.7 bits (130), Expect = 1e-06
Identities = 110/450 (24%), Positives = 148/450 (32%), Gaps = 69/450 (15%)
Query: 946 MEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAALK 1005
M KRG G T+ P ++P P A P G A PS A+
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTS-PAVIPLSPKKAPATPVTREGAAT---PSKGDLTPPAVT 1439
Query: 1006 AKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEK 1065
++K S P PATPSS PA PP+P K
Sbjct: 1440 PVSLKKAPATSAPKGG--PATPSSKGDPTLPAVTPPSP---------------------K 1476
Query: 1066 EAPSPFQALFSDIPPRYPFQALPPHYGRP--------YPFLLQPTAAADADGLAPDVPL- 1116
E P+P Q S P + P A P G P P + T ++ D +AP L
Sbjct: 1477 EPPAPKQVATSSSPKKAP--ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLL 1534
Query: 1117 ----PADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDM------- 1165
PA + AL P P PS P P+E P +A
Sbjct: 1535 SKKTPATLAPKEALIP---PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591
Query: 1166 -DEGPTEL---PPLESPLP--LPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSEC 1219
P EL P + SP P P A+ PSP G + S PS
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP----VTPSSL 1647
Query: 1220 PDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGL 1279
D P G T P A+ L + P L E P P + P++ A +G
Sbjct: 1648 KDSPTSPASVTCKMGATVP-QASKGLPAKKGPTALKEVLVAP--APESTPIITAPTRKGP 1704
Query: 1280 AQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPL 1339
S + P + +G ++ P +PV + + A S + PL
Sbjct: 1705 QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS--KTAKGKDASHSPKGPL 1762
Query: 1340 AGMNALAAAAELPQA--RPLPSPGAAGAQA 1367
A + A+ A + LP P +A A
Sbjct: 1763 APPESKASTPLTAAAFEKVLPKPESASVSA 1792
Score = 50.4 bits (119), Expect = 3e-05
Identities = 114/463 (24%), Positives = 166/463 (35%), Gaps = 98/463 (21%)
Query: 960 KAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKL------E 1013
K AT P P P + + P K V PS R P+A + +K +
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSP-----KEVPATPSSRRDPIAPTATLLSKKTPATLAPK 1545
Query: 1014 DVSKPPAYAYP---------------ATPSSHPTSPPPASPPPT-PGITRKEE--APENV 1055
+ PPA P ATPSS S PPA P T G +E P V
Sbjct: 1546 EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAV 1605
Query: 1056 VEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADAD------- 1108
KEAP+P A+ P + P A P G P + P++ D+
Sbjct: 1606 TSPS----PKEAPTP-PAVTPPSPEKGP--ATPAPKGTPTSPPVTPSSLKDSPTSPASVT 1658
Query: 1109 -GLAPDVP-----LPA-DGPERL-----ALSPEDKPIRLSPSKITEPLREGPE------- 1149
+ VP LPA GP L A +PE PI IT P R+GP+
Sbjct: 1659 CKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI------ITAPTRKGPQTKKSSAT 1712
Query: 1150 -----EEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQ 1204
+P A+ K + + P L P++ A A+ SP G +A
Sbjct: 1713 SPPICPDPSAKNGSKGPLSTV--APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAS 1770
Query: 1205 A--LSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPET---LVEAKE 1259
+A + E P P V P P L Q P + ++E+
Sbjct: 1771 TPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP-VPTLPPKQQFLPSSPGLVLESPS 1829
Query: 1260 EPVEVPVAVPVVEAVPEEGLAQVAPSES----QPTLEMSDCDVPAGEGQCPSLEPQEAVP 1315
+P+ ++ +P E ++ P +S PT + + VP + P + +
Sbjct: 1830 KPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNK--- 1886
Query: 1316 VLGSTCFLEEASSDQFLPSLED-----PLAGMNALAAAAELPQ 1353
GS E+ SD+ +P LE+ LAAAAE+ +
Sbjct: 1887 --GSG---TESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE 1924
Score = 48.1 bits (113), Expect = 1e-04
Identities = 109/432 (25%), Positives = 147/432 (34%), Gaps = 78/432 (18%)
Query: 960 KAGLATAGPGLLPRKPP--------GLAAGP-AGTYGKAVSPPPSPRASPVAALKAKVIQ 1010
K G AT P P P GLA P G AV PPSP+ P +
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP----- 1306
Query: 1011 KLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENV-VEKKDLELEKEAPS 1069
+ PPA P+ S T PP +P P P +T +P+ K P+
Sbjct: 1307 --KGAPTPPAATPPSPKGSPGTPPPKGAPTP-PAVT--PPSPKGTPTLPATTPSSKGGPT 1361
Query: 1070 PFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPE 1129
+ PP A P H G P + P +P P P A+ P
Sbjct: 1362 TPSSKEGPTPP----AATPSHKG-------GPAMTPPSPKRGPAIPSPKGDPTSPAVIP- 1409
Query: 1130 DKPIRLSPSK--ITEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAM 1187
LSP K T REG A K ++ PP +P+ L +A
Sbjct: 1410 -----LSPKKAPATPVTREG------AATPSKGDL---------TPPAVTPVSL--KKAP 1447
Query: 1188 ATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPR---VDSPGRTEPCTAALD 1244
AT +P GG S+ G P E P P+ S + P T A
Sbjct: 1448 ATSAPKGG-------PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA-P 1499
Query: 1245 LGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQ 1304
+G P + P EVP A P P A + ++ TL + +P
Sbjct: 1500 MGAPTLPAVI---PSSPKEVP-ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM-T 1554
Query: 1305 CPSLEPQEAVPV---LGSTCFLEEASSDQFL-PSLED--PLAGMNALAAAAELPQARPLP 1358
PS + A+P +T +EASS + PS P + A P + P
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP 1614
Query: 1359 SPGAAGAQALEK 1370
+P A + EK
Sbjct: 1615 TPPAVTPPSPEK 1626
Score = 47.8 bits (112), Expect = 2e-04
Identities = 165/744 (22%), Positives = 229/744 (30%), Gaps = 130/744 (17%)
Query: 15 PPPPLLSGLAMDSHRVGAATAGRLPAS--GLPG--PLPPGKYMAGLNLHPHPGEAFLGSF 70
PP P S A + + P S G P PLP G P P
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS 1075
Query: 71 VASGMGPSASSHGSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHL 130
+ P A++ SP P+ +P+P PM P P
Sbjct: 1076 LKGAPTPPAATPPSPKGGPA-----TPSPKGAPM---------------PPAATPPSPKG 1115
Query: 131 NHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHAPSARTPGGGH 190
PP G+P PS P G P GAP + + PS P GG
Sbjct: 1116 GLATPPHKGAPTTPAATPPS---------PKGGLATPPPKGAPTTPAATPPS---PKGGL 1163
Query: 191 SSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGR 250
++ P ++ G P P K P P+G + A
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSP---KGAPTTPAATPPSPKGGLATPSPKGAPTT 1220
Query: 251 QDRGPPRLAERLS-PFLAESKTKNAALQPSVLTMCNGGA------GDVGLPALVAEAGRG 303
PP L+ P + T AA PS GG G PA + +G
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSP----KGGPATPPPKGAPTPPAATPPSLKG 1276
Query: 304 GAKEAARQDEGARLLRRTETLLPGPRPCPSPLP---PPPAPPKGPPAPPAAT---PAGVY 357
G A +GA P P P P P +PPKG P PPAAT P G
Sbjct: 1277 GL--ATPPHKGA----------PNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324
Query: 358 TVFREQGREHRVV----APTFVPSVEAF--DERPGPIQIASQARDARAREREAGRPGVLQ 411
+G +P P++ A + GP +S+ + + G
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384
Query: 412 APPGSPR--PLDRPEGLREKNSVIR--------------------------------SLK 437
PP R + P+G +VI SLK
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK 1444
Query: 438 RPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERA-----PRGPAGPAAQQAAK 492
+ P AP S +PA P+ P P + A + PA PA A
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT 1504
Query: 493 LFGLEPGRPP--PTGPEHKWKPFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKA 550
L + P P P P + P A +L+ + + A +EA + A +
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRDPI------APTATLLSKKTPATLAPKEALIPPAMTVPSP 1558
Query: 551 YLDPGAVLPRSA-ATCGRPVADMHSAAHGS---GEASAMQSLIKYSGSFARDAVAVRPGG 606
P P+ A AT A A S G S + LI + + A P
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA 1618
Query: 607 CGKKSPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAF-G 665
SP G T P+ PTS + + + P + K P+++K
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSPPVTPSSLK----DSPTSPASVTCKMGATVPQASKGLPA 1674
Query: 666 REGSGAQGEAEVRHPPVGIAVAVA 689
++G A E V P + A
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITA 1698
Score = 47.4 bits (111), Expect = 2e-04
Identities = 93/423 (21%), Positives = 143/423 (33%), Gaps = 45/423 (10%)
Query: 2366 PSSTPGSKKSPPEPVDKRAKAPKARP---APPQPSPAPPAFTSCPAPEPFAELPAPATSL 2422
P+S G+ SP + K P P A P+ SP+ + +S P E SL
Sbjct: 536 PASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSL 595
Query: 2423 A-PAPLITMPATRPKP----KKARAAEESGAKGPRRPGE-----------EAELLVKLDH 2466
P P+ ++ P A + GP G A L D
Sbjct: 596 GEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADP 655
Query: 2467 EGVTSPKSKKAKEALLLREDPGAGGW------QEPKSLLSLGSYP--PAAGSSEPKAPWP 2518
GV +P + K P G P +L + P P A + P AP P
Sbjct: 656 AGV-APTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSP 714
Query: 2519 KATDGDLAQ--------EPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSS 2570
+ T LA + P + +G P K DG S +S+ + SS
Sbjct: 715 QNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKV----DGI--SHTSALAPVASSPK 768
Query: 2571 SSSSSSSGSETEGEEEGDKNGDGGCGTG-GRNCSAASSRAASPASSSSSSSSSSSSSSSS 2629
+ SG+ +G + G + S + R + S+ + + SS
Sbjct: 769 ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPV 828
Query: 2630 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAP 2689
S +S +S S S S +++ S + S + + S+ T + + P P
Sbjct: 829 SPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTP 888
Query: 2690 TAG--PSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKS 2747
+ P + T A KQA ++ SP K P P+ P P+ P A
Sbjct: 889 SVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP 948
Query: 2748 RPK 2750
PK
Sbjct: 949 SPK 951
Score = 45.4 bits (106), Expect = 8e-04
Identities = 85/362 (23%), Positives = 113/362 (31%), Gaps = 53/362 (14%)
Query: 972 PRKPPGLAAGPAGT---------YGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYA 1022
P P G+ P T + K P+P+ +P ++ + +K + P
Sbjct: 872 PLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR--ATPAPKG 929
Query: 1023 YPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRY 1082
PA+PS PPA+ PP+P +P K AP+P A P
Sbjct: 930 IPASPSPKGAPTPPAATPPSPKGGPATPSP------------KWAPTP-PAATPPSPKGG 976
Query: 1083 PFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITE 1142
P A P G P P P A + P P P P A++P S
Sbjct: 977 P--ATPSPKGAPTP----PAATPPSPKGGPATPSPKGAPTPPAVTPPSP----KGSPAAT 1026
Query: 1143 PLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLE 1202
P +G P A +G PL P P A PSP GG L+
Sbjct: 1027 PFPKGASTPP-------AATPPSPKGSPAATPL--PKGAPTTPAATLPSPKGGPATPSLK 1077
Query: 1203 AQAL--SATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAA-LDLGVQLTPETLVE--- 1256
+AT S P P P +P + A G TP
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137
Query: 1257 ---AKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEA 1313
A P P P+ GLA P + PT + P G PS +
Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLA-TPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196
Query: 1314 VP 1315
P
Sbjct: 1197 TP 1198
Score = 41.2 bits (95), Expect = 0.015
Identities = 41/157 (26%), Positives = 49/157 (31%), Gaps = 5/157 (3%)
Query: 1932 PKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDD 1991
PK GL P P A TP A P P K LA + A P + GP
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSP----KGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260
Query: 1992 D-LWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKK 2050
T + L A P + PA T KGGP + P
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320
Query: 2051 KKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKR 2087
K P G P P A PS P + T + +
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Score = 40.4 bits (93), Expect = 0.026
Identities = 39/158 (24%), Positives = 51/158 (32%), Gaps = 7/158 (4%)
Query: 1925 SPAGLLRPKKGLGEPGP-SLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFE 1983
SP G+ P K P +L P G P P + +KAR PK
Sbjct: 874 SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS 933
Query: 1984 AGPEASDDDLWTRRRSERIFLHDASAAAPAPV-STAPATKTSRCAKGGPLSPRKDAGRAK 2042
P+ + S + A P+P + P T KGGP +P
Sbjct: 934 PSPKGAPTPPAATPPSPK-----GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP 988
Query: 2043 DRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHAS 2080
P K G G P P A PS +P A+
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
Score = 38.9 bits (89), Expect = 0.077
Identities = 39/149 (26%), Positives = 44/149 (29%), Gaps = 26/149 (17%)
Query: 1932 PKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDD 1991
PK GL P P A TP A P P K LA + A P + G
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSP----KGGLATPSPKGAPTTPAATPPSPKGG------ 1231
Query: 1992 DLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKK 2051
+ +P T PA T KGGP +P P K
Sbjct: 1232 ---------------LATPSPKGAPTTPAA-TPPSPKGGPATPPPKGAPTPPAATPPSLK 1275
Query: 2052 KGKEAGPGAGLPPPRAPALPSEARAPHAS 2080
G P G P P PS P S
Sbjct: 1276 GGLATPPHKGAPNPAVVTPPSPKGGPATS 1304
Score = 38.9 bits (89), Expect = 0.077
Identities = 37/157 (23%), Positives = 51/157 (32%), Gaps = 25/157 (15%)
Query: 1937 GEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTR 1996
G P P++ P P +G +SP K P P + P
Sbjct: 1285 GAPNPAVVTP-PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP------- 1336
Query: 1997 RRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEA 2056
+ P+P T T+ +KGGP +P G P K
Sbjct: 1337 -----------AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK-----G 1380
Query: 2057 GPGAGLP-PPRAPALPSEARAPHASSLTAAKRSKAKA 2092
GP P P R PA+PS P + ++ KA A
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417
Score = 38.5 bits (88), Expect = 0.100
Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 29/176 (16%)
Query: 1932 PKKGLGEPGPS---LAAP-TPGARGPDPSSPDKAKLAV-------EKGRKARKLRGP--- 1977
P+KG P P + P TP + P+SP + KG A+K GP
Sbjct: 1624 PEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK--GPTAL 1681
Query: 1978 KEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKD 2037
KE PE++ R+ + S+A P+ P+ K GPLS
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQT---KKSSATSPPICPDPSAKNG---SKGPLSTVAP 1735
Query: 2038 AGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAK 2093
A +KD K KGK+A P+ P P E++A ++ LTAA K K
Sbjct: 1736 APLLPVQKDSSKTAKGKDASHS-----PKGPLAPPESKA--STPLTAAAFEKVLPK 1784
Score = 37.4 bits (85), Expect = 0.22
Identities = 85/346 (24%), Positives = 110/346 (31%), Gaps = 58/346 (16%)
Query: 326 PGPRPCPSPL------PPPPAPPKGPPAPPAATPAGVYTVFREQGREH-RVVAPTFVPSV 378
P P+ +PL P P P PPA TP G V G H +AP
Sbjct: 712 PSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKV---DGISHTSALAPVASSPK 768
Query: 379 EAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKR 438
E E G AS G L SP PL SV KR
Sbjct: 769 ECPTEDSGASATASS-------------KGTLTYLADSPSPLG--------VSVSPQTKR 807
Query: 439 PPP------ADAPTVR-ATRASPDPRAYVPAKELL------KPEADPRPCERAPRGPAGP 485
PP D P ++ SP +++P L P P +P+G P
Sbjct: 808 PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTP 867
Query: 486 AAQQAAKLFGLE-PGRPPPTG-----PEHKWKPFELGNFAATQMAVLAAQHHHSRAEEEA 539
+A G+ P + PT P K P A +++ ++ +RA
Sbjct: 868 SAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP 927
Query: 540 AVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDA 599
+ AS S K P A P S G P S +A K +
Sbjct: 928 KGIPASPSPKGAPTPPAATPPSPK--GGPATP--SPKWAPTPPAATPPSPKGGPATPSPK 983
Query: 600 VAVRPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAA 645
A P SP GG T P+ APT + + G PAA
Sbjct: 984 GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK----GSPAA 1025
Score = 37.4 bits (85), Expect = 0.22
Identities = 46/178 (25%), Positives = 54/178 (30%), Gaps = 11/178 (6%)
Query: 1932 PKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAV--EKGRKARKLRGPKEPGFEAGPEAS 1989
PK GL P P A TP A P P K LA KG P P +
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSP----KGGLATPPPKGAPTTPAATPPSPKGGLATPSP 1191
Query: 1990 DDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRK 2049
T + + +P T PA T KGG +P P
Sbjct: 1192 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAA-TPPSPKGGLATPSPKGAPTTPAATPPS 1250
Query: 2050 KKKGKEAGPGAGLPPPRAPALPS----EARAPHASSLTAAKRSKAKAKGKEVKKENRG 2103
K G P G P P A PS A PH + A + KG +G
Sbjct: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308
Score = 32.3 bits (72), Expect = 7.2
Identities = 34/141 (24%), Positives = 37/141 (26%), Gaps = 1/141 (0%)
Query: 1932 PKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDD 1991
PK G P P APTP A P A KG P P
Sbjct: 996 PKGGPATPSPK-GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK 1054
Query: 1992 DLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKK 2051
T + A + P T KGGP +P P K
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK 1114
Query: 2052 KGKEAGPGAGLPPPRAPALPS 2072
G P G P A PS
Sbjct: 1115 GGLATPPHKGAPTTPAATPPS 1135
Score = 32.0 bits (71), Expect = 9.4
Identities = 79/363 (21%), Positives = 129/363 (35%), Gaps = 76/363 (20%)
Query: 2290 EPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRG-------------RKP 2336
E +P + P+ K K S T +P AK +G +K
Sbjct: 1691 ESTPIITAPTRKGPQTKKSSATSPPI------CPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744
Query: 2337 SAK-AKGDRAATLEEGN--PTDEVPSTPLALE------PSSTPGSKKSPPEPVDKRAKAP 2387
S+K AKG A+ +G P + STPL P S + P P P
Sbjct: 1745 SSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP-------P 1797
Query: 2388 KARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPA------------------PLIT 2429
+ P P P P P P L +P+ LAPA P +
Sbjct: 1798 VSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQS 1857
Query: 2430 MPATRPKPKKA------RAAEESGAKGPRRPGEEA---ELLVKLDHEGVTSPKSKKAK-- 2478
+ P PK A +A++ K + G E+ E + +L+ + T +++A+
Sbjct: 1858 VLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLA 1917
Query: 2479 EALLLREDPGAGGWQ---EPKSLLSLGSYPPAAGSSEPKAPWPKA-------TDGDLAQE 2528
A + E+P + Q E K+ ++ + + K+ T D+ +
Sbjct: 1918 AAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKS 1977
Query: 2529 PGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGD 2588
P T+ G K D +Q Q A E + + ++ + + E+E EEE D
Sbjct: 1978 PASD-TYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESE-EEEVD 2035
Query: 2589 KNG 2591
+ G
Sbjct: 2036 ETG 2038
>gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
Length = 1664
Score = 77.0 bits (188), Expect = 3e-13
Identities = 90/303 (29%), Positives = 124/303 (40%), Gaps = 26/303 (8%)
Query: 2379 PVDKRAKAPKARPAPPQPSPAPP--AFTSCPAPEPFAELPAPATSLAPAPLITMPATRPK 2436
P+D+ A A P PP + A A+ +P ++ L T K
Sbjct: 1213 PLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAK 1272
Query: 2437 PKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEP- 2495
A +E G GP R + DH+ ++ K L+ + G+ W
Sbjct: 1273 HPAAVRLQE-GVHGPSRVHVGSG-----DHDYCVRSRTPPKKMPALVIPEVGSR-WNVKR 1325
Query: 2496 ------KSLLSLG-SYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQ 2548
K +LSLG + PP + + P T + A P L + SP+ +
Sbjct: 1326 HQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLA---PSSLLSPEASP 1382
Query: 2549 AEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSR 2608
D + S+ S + S S + +G + G R+ S+ S+R
Sbjct: 1383 CRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRR------GRNSRSVSSGSNR 1436
Query: 2609 AASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668
+ +SSSSSSSSSS S S S S SS SSS S SSSSSSSSSSSSSSSSS
Sbjct: 1437 TSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSS 1496
Query: 2669 SSS 2671
SSS
Sbjct: 1497 SSS 1499
Score = 68.9 bits (167), Expect = 7e-11
Identities = 98/337 (29%), Positives = 136/337 (40%), Gaps = 37/337 (10%)
Query: 2382 KRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAP---ATSLAPAPLITMPATRP--- 2435
++++A K P PP P+ + S P + P A LA +T PAT P
Sbjct: 1180 EKSEAKKECP-PPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQL 1238
Query: 2436 -KPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTS---PKSKKAKEALL--LREDPGA 2489
KP A + + AK P+ +E L EGVT P + + +E + R G+
Sbjct: 1239 WKPLAA-VSLLAKAKSPKSTAQEGTL----KPEGVTEAKHPAAVRLQEGVHGPSRVHVGS 1293
Query: 2490 GGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQA 2549
G + PA E + W D+ +P L+ + P A
Sbjct: 1294 GDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITIKPV--LSLGPAAPPPPCIAASR 1351
Query: 2550 EQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRA 2609
E S + S+ + SS S S + + C + R+
Sbjct: 1352 EPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPPEPSAKQRSMRCYRKACRS 1411
Query: 2610 ASPASS-----------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------SSSSSS 2652
ASP+S S SS S+ +S +SSSSSSSSSSS S S S S SS S
Sbjct: 1412 ASPSSQGWQGRRGRNSRSVSSGSNRTSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCS 1471
Query: 2653 SSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAP 2689
SS S SSSSSSSSSSS++ SS S +P+P
Sbjct: 1472 SSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRSPSP 1508
Score = 49.3 bits (116), Expect = 6e-05
Identities = 102/460 (22%), Positives = 161/460 (35%), Gaps = 70/460 (15%)
Query: 2322 SEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVD 2381
S P K + P KA A EG +E S L E T +K PP P
Sbjct: 1063 SPHPKHKVSALVQSPQMKAL---ACVSAEGVTVEEPASERLKPETQETRPREK-PPLPAT 1118
Query: 2382 KRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPA-----TRPK 2436
K P+ P P+ P + LP P T + + +
Sbjct: 1119 KAVPTPRQSTVPKLPAVHPARLRK------LSFLPTPRTQGSEDVVQAFISEIGIEASDL 1172
Query: 2437 PKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPK 2496
E+S AK P A+ L + GV P+ K+ + L E G P
Sbjct: 1173 SSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPA 1232
Query: 2497 SLLSLGSYPPAAGSSEPKAPWPKAT--DGDL-------AQEP----------GPGLTFED 2537
+ P AA S KA PK+T +G L A+ P GP
Sbjct: 1233 TPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVG 1292
Query: 2538 SGN------PKSPDK---------------AQAEQDGAEESESSSSSSSGSSSSSSSSSS 2576
SG+ ++P K + QD + S ++ ++S
Sbjct: 1293 SGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITIKPVLSLGPAAPPPPCIAASRE 1352
Query: 2577 SGSETEGEEEGDKNGDGGCGTGGRNCSAA------SSRAASPASSSSSSSSSSSSSSSSS 2630
E+ D + + + A+ ++R S+ S + S+
Sbjct: 1353 PLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPPEPSAKQRSMRCYRKACRSA 1412
Query: 2631 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD---------EDSSCSS 2681
S SS +S S SS S+ +S +SSSSSSSSSSS S + SSCSS
Sbjct: 1413 SPSSQGWQGRRGRNSRSVSSGSNRTSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSS 1472
Query: 2682 DDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
+ ++ S+ ++ + ++ + ++R + SP +++
Sbjct: 1473 SGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRSPSPRRRS 1512
Score = 44.7 bits (104), Expect = 0.001
Identities = 109/441 (24%), Positives = 162/441 (36%), Gaps = 82/441 (18%)
Query: 916 LQQQAAQALELQRSAQLVQERLK----AQEHRAEMEEKGSKRGLEAAGKAGLATAGP-GL 970
LQ+Q + ELQ+ + +Q + K A+ A +E K +AG++ A GP L
Sbjct: 500 LQKQPQE--ELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKEGPLDL 557
Query: 971 LPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSH 1030
P+ + P T+ V S +ASP+ P + A P++
Sbjct: 558 YPKLADTIQTNPIPTHLSLVD---SAQASPM-----------------PVDSVEADPTA- 596
Query: 1031 PTSPPPASPPPT-PGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPP 1089
P A P P PG+ +VE L E +P A + + P A+ P
Sbjct: 597 -VGPVLAGPVPVDPGLVDLASTSSELVEP--LPAEPVLINPVLADSAAVDP-----AVVP 648
Query: 1090 HYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPE 1149
P P+ A D LA P+P D L+P D P+ L S+ T+P R G
Sbjct: 649 ISDNLPPVDAVPSGPAPVD-LALVDPVPND------LTPVD-PV-LVKSRPTDP-RRGAV 698
Query: 1150 EEPL--AEREVKAEVEDMDEGPTELPPLESPLPLPAAEA-------MATPSPAGGCGGGL 1200
L + ++ E E +D T +P ++ + E+ A P P
Sbjct: 699 SSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRR 758
Query: 1201 LEAQALSATGQSCAEP--SECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVE-- 1256
Q + T + +P + P E P D P P A +Q +PET +E
Sbjct: 759 RRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEIC 818
Query: 1257 -----------AKEEPVEVPVAVPVVEAVPEEGL----------AQVAPSESQPTLEMSD 1295
+ E PV PVA E VP + + V+P+ P +
Sbjct: 819 LVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAA 878
Query: 1296 CDVPAGE-GQCPSLEPQEAVP 1315
PAG G PSL P P
Sbjct: 879 LPFPAGGLGMPPSLPPPPLQP 899
Score = 38.9 bits (89), Expect = 0.077
Identities = 68/265 (25%), Positives = 92/265 (34%), Gaps = 61/265 (23%)
Query: 975 PPGLAAG---PAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPA----TP 1027
PP ++A PAG G S PP P P L + P ++P +P
Sbjct: 872 PPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSP 931
Query: 1028 SSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDI-----PPRY 1082
S +P PPP + P G P +P + + P
Sbjct: 932 SGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHA 991
Query: 1083 PFQA------LPP-HYGRPYPFLLQP------TAAADADGLAP-------DVPLPADG-P 1121
PF + LPP GR P QP T A + + P + LP G P
Sbjct: 992 PFWSTVPPPPLPPASIGRAVP---QPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAP 1048
Query: 1122 ERLALSPEDKPIRLS--PSKITEPLREGPE--------------EEPLAEREVKAEVEDM 1165
+ E KP+ S P L + P+ EEP +ER +K E +
Sbjct: 1049 QTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASER-LKPETQ-- 1105
Query: 1166 DEGPTELPPLESPLPLPAAEAMATP 1190
E P E P PLPA +A+ TP
Sbjct: 1106 -----ETRPREKP-PLPATKAVPTP 1124
Score = 38.5 bits (88), Expect = 0.100
Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 2353 PTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPF 2412
P P++P P S P + SP E V + ARP+PP S +P T P
Sbjct: 821 PVGPSPASPSPEPPVSKPVAS-SPTEQVPSQEMPLLARPSPPVQSVSPAVPT---PPSMS 876
Query: 2413 AELPAPATSLAPAPLITMPATRP 2435
A LP PA L P + P +P
Sbjct: 877 AALPFPAGGLGMPPSLPPPPLQP 899
Score = 35.0 bits (79), Expect = 1.1
Identities = 85/333 (25%), Positives = 119/333 (35%), Gaps = 52/333 (15%)
Query: 326 PGPRPCPSPLPPPPAPPKGPPAPPAAT----PAGVYTVFREQGREHRVVAPTFVPSVEAF 381
PG P P APP P +P ++T P G G +H AP F +V
Sbjct: 950 PGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLG-----WGPGPQH---AP-FWSTVPPP 1000
Query: 382 DERPGPIQIASQARDARAREREAGRP-GVLQAPPGSPRPLDRP-EGLREKNSVIRSLKRP 439
P I A +R AG P VL P L P G + +K
Sbjct: 1001 PLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPV 1060
Query: 440 PPADAP--TVRATRASPDPRAYV-----------PAKELLKPEA-DPRPCERAP----RG 481
P + P V A SP +A PA E LKPE + RP E+ P +
Sbjct: 1061 PASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKA 1120
Query: 482 PAGPAAQQAAKLFGLEPGR---------PPPTGPEHKWKPF--ELGNFAATQMAVLAAQH 530
P KL + P R P G E + F E+G A+ ++ L Q
Sbjct: 1121 VPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIG-IEASDLSSLLEQF 1179
Query: 531 HHSRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVA-DMHSAAHGSGEASAMQSLI 589
S A++E A + S G +P+ R A ++ + A + A+ L
Sbjct: 1180 EKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLW 1239
Query: 590 KYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPE 622
K + + A A P ++ GT+KPE
Sbjct: 1240 KPLAAVSLLAKAKSPKSTAQE------GTLKPE 1266
Score = 33.5 bits (75), Expect = 3.2
Identities = 34/123 (27%), Positives = 47/123 (38%), Gaps = 21/123 (17%)
Query: 2333 GRKPSAKAKGDRAATLEEGNPTDEVPST--PLALEPSSTPGSKKSPPEPVDKRAKA---- 2386
G P++ + + +PT++VPS PL PS P SP P A
Sbjct: 823 GPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSP-PVQSVSPAVPTPPSMSAALPF 881
Query: 2387 -------PKARPAPPQPSPAPPAFTSCPAPEPF---AELPA----PATSLAPAPLITMPA 2432
P + P PP P+ P P+PF A LP+ P S + P + P
Sbjct: 882 PAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPP 941
Query: 2433 TRP 2435
T P
Sbjct: 942 TVP 944
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 76.3 bits (186), Expect = 4e-13
Identities = 94/453 (20%), Positives = 162/453 (35%), Gaps = 46/453 (10%)
Query: 2353 PTDEVPSTPLALEPSSTPGSKKSPPE---PVDKRAKAPKA--RPAPPQPSPAPPAFTSCP 2407
P P+TP L P++ + PE P +A AP PAP P P P
Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 562
Query: 2408 APEPFAEL---------------PAPATSLAPAPLITMPATRPKPKKAR----AAEESGA 2448
AP E PAP T PAP P T +P A
Sbjct: 563 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 622
Query: 2449 KGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRED-PGAGGWQEPKSLLSLGSYPPA 2507
P P E A K +P + K L+E P PK L + P
Sbjct: 623 TAPTTPKEPAPTTPK-----EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 677
Query: 2508 AGSSEPKAP-WPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSG 2566
+ +S+ AP PK T +EP P PK P E SE S+ +++
Sbjct: 678 STTSDKPAPTTPKETAPTTPKEPAP-------TTPKKPAPTTPETPPPTTSEVSTPTTTK 730
Query: 2567 SSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSS 2626
++ S + E K + G + AA+ ++++ ++
Sbjct: 731 EPTTIHKSPDESTPELSAEPTPKALENSPKEPG--VPTTKTPAATKPEMTTTAKDKTTER 788
Query: 2627 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAA 2686
++ +++++ + +++++ ++ S +++++ +S+++ TT + A
Sbjct: 789 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 848
Query: 2687 PAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAK 2746
P T K A+P + K P+PQ P P +P K K
Sbjct: 849 PKVTTTKKTITTTEI-MNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK---PK 904
Query: 2747 SRPKKREGVHLPTTKELAKRQRLPSVENRPKIA 2779
+ P+ R+ PT +++ +P + +IA
Sbjct: 905 TMPRVRKPKTTPTPRKMT--STMPELNPTSRIA 935
Score = 69.7 bits (169), Expect = 4e-11
Identities = 99/444 (22%), Positives = 157/444 (35%), Gaps = 53/444 (11%)
Query: 2335 KPSAKA----KGDRAATLEEGNPT------DEVPSTPLALEPSSTPGSKKSPPEPVDKRA 2384
KP+ KA KG T +E PT P P S P + K P K
Sbjct: 196 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK-- 253
Query: 2385 KAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAE 2444
AP P P T PAP E PAP T+ PAP T A P K A
Sbjct: 254 ------SAPTTPKEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSA--PTTPKEPAPT 304
Query: 2445 ESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSY 2504
P P E A K P KE ++P +EP +
Sbjct: 305 TPKKPAPTTPKEPAPTTPK-------EPTPTTPKEPAPTTKEPAPTTPKEPAP-----TA 352
Query: 2505 PPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSS 2564
P + PK P P +EP P T E S P +P K A ++ +
Sbjct: 353 PKKPAPTTPKEPAPTT-----PKEPAPTTTKEPS--PTTP-KEPAPTTTKSAPTTTKEPA 404
Query: 2565 SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSS 2624
++ S+ ++ S T +E T + + + + +P ++ + +
Sbjct: 405 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP---TTPKEPAPT 461
Query: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDE 2684
++ + ++ + ++ ++ ++ + ++ + ++ + TT E+ + ++ +E
Sbjct: 462 TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 521
Query: 2685 AAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAP----QPQAPPPQPTQPLQPK 2740
P PT P A KA P+ +P K PAP +P P+ T P PK
Sbjct: 522 --PTPTT-PEEPAPTTPKAAAPNTPKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPK 576
Query: 2741 AQAGAKSRPKKREGVHLPTTKELA 2764
A + P KELA
Sbjct: 577 GTAPTTLKEPAPTTPKKPAPKELA 600
Score = 54.3 bits (129), Expect = 2e-06
Identities = 87/367 (23%), Positives = 122/367 (33%), Gaps = 40/367 (10%)
Query: 972 PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSH 1030
P+KP P PA T K +P + SP K PA P T S
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP-------------KEPA---PTTTKSA 396
Query: 1031 PTSPPPASPPPTPG--ITRKEEAPENVVEKKDLELEKEAPS----PFQALFSDIPPRYPF 1084
PT+ +P T T KE +P E ++ AP+ P + P P
Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 456
Query: 1085 QALPPHYGRPYPFLLQPTAAADADGLAPDVP--LPADGPERLALSPEDKPI-----RLSP 1137
+ P +P P + A AP P L PE+LA + +KP L+P
Sbjct: 457 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 516
Query: 1138 SKITEPLREGPEEEPLAEREVKAEVEDMDEGPT---ELPPLESPLPLPAAEAMATPSPAG 1194
+ EP PEE + A + PT E P P P P+
Sbjct: 517 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 576
Query: 1195 GCGGGLLEAQALSATGQSCAEPSECPDFVEGP-EPRVDSPGRTEPCTAALDLGVQLTPET 1253
G L+ A T + A P + P D P T P A + P T
Sbjct: 577 GTAPTTLKEPA-PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 635
Query: 1254 LVEAKEEPVEVPVAVPVVEAVP----EEGLAQVAPSESQ-PTLEMSDCDVPAGEGQCPSL 1308
E + + E P + ++AP+ ++ PT SD P +
Sbjct: 636 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 695
Query: 1309 EPQEAVP 1315
P+E P
Sbjct: 696 TPKEPAP 702
Score = 49.3 bits (116), Expect = 6e-05
Identities = 75/411 (18%), Positives = 148/411 (36%), Gaps = 30/411 (7%)
Query: 2368 STPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPF-AELPAPATSLAPAP 2426
+TP + + V K A+P P+PS P + TS E
Sbjct: 100 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 159
Query: 2427 LITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRED 2486
T + K A+ + + +++L K + T+ K AL ++
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG----PALTTPKE 215
Query: 2487 PGAGGWQEPKSLLSLGSYPPAAGS--SEPKAPWPKATDG--DLAQEPGPGLTFEDS-GNP 2541
P +EP S P S + PK P P T +EP P T E + P
Sbjct: 216 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 275
Query: 2542 KSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRN 2601
K P ++ ++S+ ++ + ++ + T +E T +
Sbjct: 276 KEPAPTTTKEPAPTTTKSAPTT---PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 332
Query: 2602 CSAASSRAA----------SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2651
+ + A +P + ++ + ++ + +++ S ++ + ++
Sbjct: 333 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 392
Query: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKAR 2711
+ S+ +++ + +++ S+ TT ++ S ++ E PAPT P K K
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE--PAPTTPKEPAPTTPKKPAPTTPK-E 449
Query: 2712 PSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKE 2762
P+ +P + P + P P +P + A + PKK PTT E
Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL----TPTTPE 496
Score = 48.9 bits (115), Expect = 7e-05
Identities = 78/339 (23%), Positives = 108/339 (31%), Gaps = 28/339 (8%)
Query: 972 PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSH 1030
P++P P PA T K +P + +P A K E P P TP
Sbjct: 259 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPTTPKKPAPTTPKEP 317
Query: 1031 -PTSPPPASP--PPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQAL 1087
PT+P +P P P T KE AP E +K AP+ + + P P +
Sbjct: 318 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK----EPAPTTPKEPA 373
Query: 1088 PPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREG 1147
P P P + A PA + A + +P SP+ EP
Sbjct: 374 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP---SPTTTKEPAPTT 430
Query: 1148 PEEEPLAEREVKAEVEDMDEGP-TELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQAL 1206
P+E + A + P T P + PA P+P + L
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 490
Query: 1207 SATGQSCAEPSE------------CPDFVEGPEPRV-DSPGRTEPCTAALDLGVQLTPET 1253
+ T P+ P E P P + P T P AA + + P T
Sbjct: 491 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 550
Query: 1254 LVEAKEEPVEVPVAVPVVEAVP--EEGLAQVAPSESQPT 1290
E + P E P +G A E PT
Sbjct: 551 PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 589
Score = 48.1 bits (113), Expect = 1e-04
Identities = 70/328 (21%), Positives = 102/328 (31%), Gaps = 39/328 (11%)
Query: 973 RKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPS--- 1028
+KP P PA T K +P + +P K + P P TP
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523
Query: 1029 -SHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIP----PRYP 1083
+ P P P +P T KE AP E ++ AP+ + P P
Sbjct: 524 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 583
Query: 1084 FQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPED------------K 1131
+ P +P P L PT + D P P +P++
Sbjct: 584 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 643
Query: 1132 PIRLSPSKITEPLREGPEE---EPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMA 1188
P +P+ + EP P++ + LA K + P P E+ P A
Sbjct: 644 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 703
Query: 1189 TPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQ 1248
TP A T P + P SP + P +L +
Sbjct: 704 TPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP-----ELSAE 749
Query: 1249 LTPETLVEAKEEPVEVPVAVPVVEAVPE 1276
TP+ L + +EP VP PE
Sbjct: 750 PTPKALENSPKEP-GVPTTKTPAATKPE 776
Score = 46.6 bits (109), Expect = 4e-04
Identities = 84/358 (23%), Positives = 114/358 (31%), Gaps = 59/358 (16%)
Query: 960 KAGLATAGPGLL-PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSK 1017
KA T GP L P++P P PA T K +P I+ K
Sbjct: 200 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPT--------------TIKSAPTTPK 245
Query: 1018 PPAYAYPATPSSHPTSP--------------PPASPPPT----PGITRKEEAPENVVEKK 1059
PA P T S PT+P P P PT P T + AP E
Sbjct: 246 EPA---PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 302
Query: 1060 DLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQ--PTAAADADGLAPDVPLP 1117
+K AP+ + + P P + P P P + PT + AP P P
Sbjct: 303 PTTPKKPAPTTPK----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 1118 ADGPERLALSPEDKPIRL----SPSKITEPLREGPEEEPLAERE-VKAEVEDMDEGPTEL 1172
E +P++ SP+ EP + P +E + P E
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418
Query: 1173 PPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDS 1232
P + P P P+ + A + + ++ P EP +
Sbjct: 419 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 478
Query: 1233 PGRTEPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPT 1290
P T P T +LTP T + E P PEE LA P E PT
Sbjct: 479 PKETAPTTPK-----KLTPTTPEKLAPTTPEKP-----APTTPEE-LAPTTPEEPTPT 525
Score = 46.6 bits (109), Expect = 4e-04
Identities = 42/174 (24%), Positives = 65/174 (37%), Gaps = 11/174 (6%)
Query: 2290 EPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKA-KGDRAATL 2348
+P+P L P+ + T+ D P A ++P+ KG TL
Sbjct: 593 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 652
Query: 2349 EEGNPTDEVPSTPLALEPSSTPG---SKKSPPEPVDKRAKAPKARPAPPQPSPA---PPA 2402
+E PT P L P++T G + P P + AP P +P+P PA
Sbjct: 653 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT---PKEPAPTTPKKPA 709
Query: 2403 FTSCPAPEP-FAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPG 2455
T+ P P +E+ P T+ P + P A ++ P+ PG
Sbjct: 710 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 763
Score = 45.4 bits (106), Expect = 8e-04
Identities = 73/312 (23%), Positives = 99/312 (31%), Gaps = 34/312 (10%)
Query: 999 SPVAALKAKVIQKLEDVSKPPAYAYPATPS----SHPTSPPPASPPPTP----GITRKEE 1050
+P + + AK K E +K PA P P+ P S P P PT T KE
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 1051 APENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQ--PTAAADAD 1108
AP K + P+P + P P + P P P + PT +
Sbjct: 248 APTTT---KSAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 302
Query: 1109 GLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAERE-----VKAEVE 1163
P P P E +P++ +P+ EP E P +E K
Sbjct: 303 PTTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 1164 DMDEGPTELPPLESPLPLPAAEAMAT----PSPAGGCGGGLLEAQALSATGQSCAEPSEC 1219
+ P P E P P E T P+P + T +S +
Sbjct: 359 TTPKEPAPTTPKE-PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417
Query: 1220 PDFVEGPEPRVDSPGRTEPCTAALDLGVQLTP-ETLVEAKEEPVEVPVAVPVVEAVPEEG 1278
P EP +P EP TP E +EP P P+E
Sbjct: 418 PSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP-APTTPKEP 474
Query: 1279 LAQVAPSESQPT 1290
A P E+ PT
Sbjct: 475 -APTTPKETAPT 485
Score = 42.0 bits (97), Expect = 0.009
Identities = 39/217 (17%), Positives = 89/217 (41%), Gaps = 27/217 (12%)
Query: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615
E++ +++++ +S+ ++S ET+ E+ T ++ + S A P
Sbjct: 151 ETKETTTTNKQTSTDGKEKTTSAKETQSIEK----------TSAKDLAPTSKVLAKPTPK 200
Query: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
+ +++ + ++ + ++ +S++ + ++ S+ ++ + +++ S+ TT +
Sbjct: 201 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 260
Query: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPP-PQPT 2734
+ + ++ E PAPT P A TK P T P P P PT
Sbjct: 261 EPAPTTTKE--PAPTT-PKEPAPTTTK-------------EPAPTTTKSAPTTPKEPAPT 304
Query: 2735 QPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPS 2771
P +P + P + T KE A + P+
Sbjct: 305 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 341
Score = 40.4 bits (93), Expect = 0.026
Identities = 42/185 (22%), Positives = 77/185 (41%), Gaps = 11/185 (5%)
Query: 2587 GDKNGDGGCGTGGRNCSAASSRAASPASSSSS------SSSSSSSSSSSSSSSSSSSSSS 2640
G NGD T + + + + SP +++ S +S +S +S + + ++
Sbjct: 91 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV 150
Query: 2641 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALP 2700
+ +++++ +S+ ++S+ + S T+ +D + +S A P P A + +
Sbjct: 151 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 210
Query: 2701 TKATKQAGKARPSAHSPGKKTP-APQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPT 2759
T K+ P P TP P P PT P +P A KS P + T
Sbjct: 211 T-TPKEPTPTTPK--EPASTTPKEPTPTTIKSAPTTPKEP-APTTTKSAPTTPKEPAPTT 266
Query: 2760 TKELA 2764
TKE A
Sbjct: 267 TKEPA 271
Score = 40.4 bits (93), Expect = 0.026
Identities = 46/189 (24%), Positives = 60/189 (31%), Gaps = 19/189 (10%)
Query: 330 PCPS-PLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPI 388
P P+ P P P PK PAP T + APT S + P P
Sbjct: 348 PAPTAPKKPAPTTPK-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP- 405
Query: 389 QIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPAD----A 444
+ + A +E + P +P+ P K + K P P A
Sbjct: 406 ---TTTKSAPTTPKEPSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPKEPAPTTPKEPA 459
Query: 445 PTVRATRASPDPRAYVPAKELLKPEADPR------PCERAPRGPAGPAAQQAAKLFGLEP 498
PT A P+ P P+ P + AP P PA +L P
Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 519
Query: 499 GRPPPTGPE 507
P PT PE
Sbjct: 520 EEPTPTTPE 528
Score = 38.1 bits (87), Expect = 0.13
Identities = 35/157 (22%), Positives = 61/157 (38%), Gaps = 20/157 (12%)
Query: 2344 RAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAF 2403
+ TL+ +V +T + + + +P D+ + P P +P+ AP
Sbjct: 838 KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKP 897
Query: 2404 TSCPAPEPFAELPAPATSLAPAPLI-TMPATRPKPKKARAAEESGAKGPRRPGEEAELLV 2462
TS P+ + P T+ P + TMP P + A A ++ + + P + LV
Sbjct: 898 TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK---LV 954
Query: 2463 KLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLL 2499
++ +PKS ED G + P LL
Sbjct: 955 EV------NPKS----------EDAGGAEGETPHMLL 975
Score = 36.6 bits (83), Expect = 0.38
Identities = 52/215 (24%), Positives = 76/215 (35%), Gaps = 36/215 (16%)
Query: 2288 CAEPSPALLVPSA----KRRSRKTSKDTGEGKDGGTAGS--EEPGAKARGRGRKPSAK-- 2339
C +P+P +A K + T K+ GTA + +EP A +KP+ K
Sbjct: 612 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP---APTTPKKPAPKEL 668
Query: 2340 ----AKGDRAATLEEGNPT---DEVPSTPLALEPSSTPGSKKSP-----PEPVDKRAKAP 2387
KG + T ++ PT + P+TP EP+ T K +P P P P
Sbjct: 669 APTTTKGPTSTTSDKPAPTTPKETAPTTPK--EPAPTTPKKPAPTTPETPPPTTSEVSTP 726
Query: 2388 KARPAP----PQPSPAPPAFTSCPAPEPFAELP-APATSLAPAPLITMP--ATRPKPKKA 2440
P P + P ++ P P+ P P P T P T K K
Sbjct: 727 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT 786
Query: 2441 ----RAAEESGAKGPRRPGEEAELLVKLDHEGVTS 2471
R E+ P+ E A K +T+
Sbjct: 787 ERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 821
Score = 35.0 bits (79), Expect = 1.1
Identities = 46/194 (23%), Positives = 61/194 (31%), Gaps = 19/194 (9%)
Query: 332 PSPLPPPPAPPKGPPAPPAATP-AGVYTVFREQG----REHRVVAP------TFVPSVEA 380
P+P P A P P P TP T +E +E P T
Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 589
Query: 381 FDERPGPIQIA-SQARDARAREREAGRP----GVLQAPPGSPRPL--DRPEGLREKNSVI 433
++P P ++A + ++ + + P G P P P P K +
Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 649
Query: 434 RSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKL 493
+LK P P P A + P A P E AP P PA K
Sbjct: 650 TTLKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 708
Query: 494 FGLEPGRPPPTGPE 507
P PPPT E
Sbjct: 709 APTTPETPPPTTSE 722
Score = 34.7 bits (78), Expect = 1.4
Identities = 102/532 (19%), Positives = 148/532 (27%), Gaps = 46/532 (8%)
Query: 4 RDFGPQRSVHGPPPP----LLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLH 59
+D P V P P G A+ + + T + PAS P P +
Sbjct: 185 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 244
Query: 60 PHPGEAFLGSFVASGMGPSASSHGSPVPL----PSDLSFRSPTPSNLPMVQLWAAHAHEG 115
P S + P+ ++ P P P+ + + P P+
Sbjct: 245 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304
Query: 116 FSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGS 175
P+ P P + P + +P+ T K P P AP +
Sbjct: 305 TPKKPAPTTPK-----EPAPTTPKEPTPTTPKEPA--PTTKEPAPT-----TPKEPAPTA 352
Query: 176 LHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGP 235
AP+ + PA ++ P + EP P K P E A
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK-----EPAPTTTKSAPTTTKEPAPTT 407
Query: 236 RGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPA 295
T + + P + +P + +P+ T PA
Sbjct: 408 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 467
Query: 296 LVA--EAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATP 353
E KE A E L P P+P P P P P TP
Sbjct: 468 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 527
Query: 354 AGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAP 413
+ + P E P + ++ + P L+ P
Sbjct: 528 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTTLKEP 586
Query: 414 ----PGSPRPLD-RPEGLREKNSVIRSLKRP--PPADAPTVRATRASPDPRAYVP----- 461
P P P + P +E S P P APT A P+ P
Sbjct: 587 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 646
Query: 462 -AKELLKPEA-----DPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPE 507
A LK A P P E AP GP + + K P PT P+
Sbjct: 647 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 698
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 76.3 bits (186), Expect = 4e-13
Identities = 94/453 (20%), Positives = 162/453 (35%), Gaps = 46/453 (10%)
Query: 2353 PTDEVPSTPLALEPSSTPGSKKSPPE---PVDKRAKAPKA--RPAPPQPSPAPPAFTSCP 2407
P P+TP L P++ + PE P +A AP PAP P P P
Sbjct: 544 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 603
Query: 2408 APEPFAEL---------------PAPATSLAPAPLITMPATRPKPKKAR----AAEESGA 2448
AP E PAP T PAP P T +P A
Sbjct: 604 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 663
Query: 2449 KGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRED-PGAGGWQEPKSLLSLGSYPPA 2507
P P E A K +P + K L+E P PK L + P
Sbjct: 664 TAPTTPKEPAPTTPK-----EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 718
Query: 2508 AGSSEPKAP-WPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSG 2566
+ +S+ AP PK T +EP P PK P E SE S+ +++
Sbjct: 719 STTSDKPAPTTPKETAPTTPKEPAP-------TTPKKPAPTTPETPPPTTSEVSTPTTTK 771
Query: 2567 SSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSS 2626
++ S + E K + G + AA+ ++++ ++
Sbjct: 772 EPTTIHKSPDESTPELSAEPTPKALENSPKEPG--VPTTKTPAATKPEMTTTAKDKTTER 829
Query: 2627 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAA 2686
++ +++++ + +++++ ++ S +++++ +S+++ TT + A
Sbjct: 830 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 889
Query: 2687 PAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAK 2746
P T K A+P + K P+PQ P P +P K K
Sbjct: 890 PKVTTTKKTITTTEI-MNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK---PK 945
Query: 2747 SRPKKREGVHLPTTKELAKRQRLPSVENRPKIA 2779
+ P+ R+ PT +++ +P + +IA
Sbjct: 946 TMPRVRKPKTTPTPRKMT--STMPELNPTSRIA 976
Score = 69.7 bits (169), Expect = 4e-11
Identities = 99/444 (22%), Positives = 157/444 (35%), Gaps = 53/444 (11%)
Query: 2335 KPSAKA----KGDRAATLEEGNPT------DEVPSTPLALEPSSTPGSKKSPPEPVDKRA 2384
KP+ KA KG T +E PT P P S P + K P K
Sbjct: 237 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK-- 294
Query: 2385 KAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAE 2444
AP P P T PAP E PAP T+ PAP T A P K A
Sbjct: 295 ------SAPTTPKEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSA--PTTPKEPAPT 345
Query: 2445 ESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSY 2504
P P E A K P KE ++P +EP +
Sbjct: 346 TPKKPAPTTPKEPAPTTPK-------EPTPTTPKEPAPTTKEPAPTTPKEPAP-----TA 393
Query: 2505 PPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSS 2564
P + PK P P +EP P T E S P +P K A ++ +
Sbjct: 394 PKKPAPTTPKEPAPTT-----PKEPAPTTTKEPS--PTTP-KEPAPTTTKSAPTTTKEPA 445
Query: 2565 SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSS 2624
++ S+ ++ S T +E T + + + + +P ++ + +
Sbjct: 446 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP---TTPKEPAPT 502
Query: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDE 2684
++ + ++ + ++ ++ ++ + ++ + ++ + TT E+ + ++ +E
Sbjct: 503 TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 562
Query: 2685 AAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAP----QPQAPPPQPTQPLQPK 2740
P PT P A KA P+ +P K PAP +P P+ T P PK
Sbjct: 563 --PTPTT-PEEPAPTTPKAAAPNTPKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPK 617
Query: 2741 AQAGAKSRPKKREGVHLPTTKELA 2764
A + P KELA
Sbjct: 618 GTAPTTLKEPAPTTPKKPAPKELA 641
Score = 54.3 bits (129), Expect = 2e-06
Identities = 87/367 (23%), Positives = 122/367 (33%), Gaps = 40/367 (10%)
Query: 972 PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSH 1030
P+KP P PA T K +P + SP K PA P T S
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP-------------KEPA---PTTTKSA 437
Query: 1031 PTSPPPASPPPTPG--ITRKEEAPENVVEKKDLELEKEAPS----PFQALFSDIPPRYPF 1084
PT+ +P T T KE +P E ++ AP+ P + P P
Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 497
Query: 1085 QALPPHYGRPYPFLLQPTAAADADGLAPDVP--LPADGPERLALSPEDKPI-----RLSP 1137
+ P +P P + A AP P L PE+LA + +KP L+P
Sbjct: 498 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 557
Query: 1138 SKITEPLREGPEEEPLAEREVKAEVEDMDEGPT---ELPPLESPLPLPAAEAMATPSPAG 1194
+ EP PEE + A + PT E P P P P+
Sbjct: 558 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 617
Query: 1195 GCGGGLLEAQALSATGQSCAEPSECPDFVEGP-EPRVDSPGRTEPCTAALDLGVQLTPET 1253
G L+ A T + A P + P D P T P A + P T
Sbjct: 618 GTAPTTLKEPA-PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 676
Query: 1254 LVEAKEEPVEVPVAVPVVEAVP----EEGLAQVAPSESQ-PTLEMSDCDVPAGEGQCPSL 1308
E + + E P + ++AP+ ++ PT SD P +
Sbjct: 677 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 736
Query: 1309 EPQEAVP 1315
P+E P
Sbjct: 737 TPKEPAP 743
Score = 49.3 bits (116), Expect = 6e-05
Identities = 75/411 (18%), Positives = 148/411 (36%), Gaps = 30/411 (7%)
Query: 2368 STPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPF-AELPAPATSLAPAP 2426
+TP + + V K A+P P+PS P + TS E
Sbjct: 141 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 200
Query: 2427 LITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRED 2486
T + K A+ + + +++L K + T+ K AL ++
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG----PALTTPKE 256
Query: 2487 PGAGGWQEPKSLLSLGSYPPAAGS--SEPKAPWPKATDG--DLAQEPGPGLTFEDS-GNP 2541
P +EP S P S + PK P P T +EP P T E + P
Sbjct: 257 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 316
Query: 2542 KSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRN 2601
K P ++ ++S+ ++ + ++ + T +E T +
Sbjct: 317 KEPAPTTTKEPAPTTTKSAPTT---PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 373
Query: 2602 CSAASSRAA----------SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2651
+ + A +P + ++ + ++ + +++ S ++ + ++
Sbjct: 374 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 433
Query: 2652 SSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKAR 2711
+ S+ +++ + +++ S+ TT ++ S ++ E PAPT P K K
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE--PAPTTPKEPAPTTPKKPAPTTPK-E 490
Query: 2712 PSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKE 2762
P+ +P + P + P P +P + A + PKK PTT E
Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL----TPTTPE 537
Score = 48.9 bits (115), Expect = 7e-05
Identities = 78/339 (23%), Positives = 108/339 (31%), Gaps = 28/339 (8%)
Query: 972 PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSH 1030
P++P P PA T K +P + +P A K E P P TP
Sbjct: 300 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPTTPKKPAPTTPKEP 358
Query: 1031 -PTSPPPASP--PPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQAL 1087
PT+P +P P P T KE AP E +K AP+ + + P P +
Sbjct: 359 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK----EPAPTTPKEPA 414
Query: 1088 PPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREG 1147
P P P + A PA + A + +P SP+ EP
Sbjct: 415 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP---SPTTTKEPAPTT 471
Query: 1148 PEEEPLAEREVKAEVEDMDEGP-TELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQAL 1206
P+E + A + P T P + PA P+P + L
Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 531
Query: 1207 SATGQSCAEPSE------------CPDFVEGPEPRV-DSPGRTEPCTAALDLGVQLTPET 1253
+ T P+ P E P P + P T P AA + + P T
Sbjct: 532 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 591
Query: 1254 LVEAKEEPVEVPVAVPVVEAVP--EEGLAQVAPSESQPT 1290
E + P E P +G A E PT
Sbjct: 592 PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 630
Score = 48.1 bits (113), Expect = 1e-04
Identities = 70/328 (21%), Positives = 102/328 (31%), Gaps = 39/328 (11%)
Query: 973 RKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPS--- 1028
+KP P PA T K +P + +P K + P P TP
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564
Query: 1029 -SHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIP----PRYP 1083
+ P P P +P T KE AP E ++ AP+ + P P
Sbjct: 565 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 624
Query: 1084 FQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPED------------K 1131
+ P +P P L PT + D P P +P++
Sbjct: 625 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 684
Query: 1132 PIRLSPSKITEPLREGPEE---EPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMA 1188
P +P+ + EP P++ + LA K + P P E+ P A
Sbjct: 685 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 744
Query: 1189 TPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQ 1248
TP A T P + P SP + P +L +
Sbjct: 745 TPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP-----ELSAE 790
Query: 1249 LTPETLVEAKEEPVEVPVAVPVVEAVPE 1276
TP+ L + +EP VP PE
Sbjct: 791 PTPKALENSPKEP-GVPTTKTPAATKPE 817
Score = 46.6 bits (109), Expect = 4e-04
Identities = 84/358 (23%), Positives = 114/358 (31%), Gaps = 59/358 (16%)
Query: 960 KAGLATAGPGLL-PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSK 1017
KA T GP L P++P P PA T K +P I+ K
Sbjct: 241 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPT--------------TIKSAPTTPK 286
Query: 1018 PPAYAYPATPSSHPTSP--------------PPASPPPT----PGITRKEEAPENVVEKK 1059
PA P T S PT+P P P PT P T + AP E
Sbjct: 287 EPA---PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 343
Query: 1060 DLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQ--PTAAADADGLAPDVPLP 1117
+K AP+ + + P P + P P P + PT + AP P P
Sbjct: 344 PTTPKKPAPTTPK----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 1118 ADGPERLALSPEDKPIRL----SPSKITEPLREGPEEEPLAERE-VKAEVEDMDEGPTEL 1172
E +P++ SP+ EP + P +E + P E
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459
Query: 1173 PPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDS 1232
P + P P P+ + A + + ++ P EP +
Sbjct: 460 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 519
Query: 1233 PGRTEPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPT 1290
P T P T +LTP T + E P PEE LA P E PT
Sbjct: 520 PKETAPTTPK-----KLTPTTPEKLAPTTPEKP-----APTTPEE-LAPTTPEEPTPT 566
Score = 46.6 bits (109), Expect = 4e-04
Identities = 42/174 (24%), Positives = 65/174 (37%), Gaps = 11/174 (6%)
Query: 2290 EPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKA-KGDRAATL 2348
+P+P L P+ + T+ D P A ++P+ KG TL
Sbjct: 634 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 693
Query: 2349 EEGNPTDEVPSTPLALEPSSTPG---SKKSPPEPVDKRAKAPKARPAPPQPSPA---PPA 2402
+E PT P L P++T G + P P + AP P +P+P PA
Sbjct: 694 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT---PKEPAPTTPKKPA 750
Query: 2403 FTSCPAPEP-FAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPG 2455
T+ P P +E+ P T+ P + P A ++ P+ PG
Sbjct: 751 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 804
Score = 45.4 bits (106), Expect = 8e-04
Identities = 73/312 (23%), Positives = 99/312 (31%), Gaps = 34/312 (10%)
Query: 999 SPVAALKAKVIQKLEDVSKPPAYAYPATPS----SHPTSPPPASPPPTP----GITRKEE 1050
+P + + AK K E +K PA P P+ P S P P PT T KE
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 1051 APENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQ--PTAAADAD 1108
AP K + P+P + P P + P P P + PT +
Sbjct: 289 APTTT---KSAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 343
Query: 1109 GLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAERE-----VKAEVE 1163
P P P E +P++ +P+ EP E P +E K
Sbjct: 344 PTTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 1164 DMDEGPTELPPLESPLPLPAAEAMAT----PSPAGGCGGGLLEAQALSATGQSCAEPSEC 1219
+ P P E P P E T P+P + T +S +
Sbjct: 400 TTPKEPAPTTPKE-PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458
Query: 1220 PDFVEGPEPRVDSPGRTEPCTAALDLGVQLTP-ETLVEAKEEPVEVPVAVPVVEAVPEEG 1278
P EP +P EP TP E +EP P P+E
Sbjct: 459 PSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP-APTTPKEP 515
Query: 1279 LAQVAPSESQPT 1290
A P E+ PT
Sbjct: 516 -APTTPKETAPT 526
Score = 42.0 bits (97), Expect = 0.009
Identities = 39/217 (17%), Positives = 89/217 (41%), Gaps = 27/217 (12%)
Query: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615
E++ +++++ +S+ ++S ET+ E+ T ++ + S A P
Sbjct: 192 ETKETTTTNKQTSTDGKEKTTSAKETQSIEK----------TSAKDLAPTSKVLAKPTPK 241
Query: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
+ +++ + ++ + ++ +S++ + ++ S+ ++ + +++ S+ TT +
Sbjct: 242 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 301
Query: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPP-PQPT 2734
+ + ++ E PAPT P A TK P T P P P PT
Sbjct: 302 EPAPTTTKE--PAPTT-PKEPAPTTTK-------------EPAPTTTKSAPTTPKEPAPT 345
Query: 2735 QPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPS 2771
P +P + P + T KE A + P+
Sbjct: 346 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 382
Score = 40.4 bits (93), Expect = 0.026
Identities = 42/185 (22%), Positives = 77/185 (41%), Gaps = 11/185 (5%)
Query: 2587 GDKNGDGGCGTGGRNCSAASSRAASPASSSSS------SSSSSSSSSSSSSSSSSSSSSS 2640
G NGD T + + + + SP +++ S +S +S +S + + ++
Sbjct: 132 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV 191
Query: 2641 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALP 2700
+ +++++ +S+ ++S+ + S T+ +D + +S A P P A + +
Sbjct: 192 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 251
Query: 2701 TKATKQAGKARPSAHSPGKKTP-APQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPT 2759
T K+ P P TP P P PT P +P A KS P + T
Sbjct: 252 T-TPKEPTPTTPK--EPASTTPKEPTPTTIKSAPTTPKEP-APTTTKSAPTTPKEPAPTT 307
Query: 2760 TKELA 2764
TKE A
Sbjct: 308 TKEPA 312
Score = 40.4 bits (93), Expect = 0.026
Identities = 46/189 (24%), Positives = 60/189 (31%), Gaps = 19/189 (10%)
Query: 330 PCPS-PLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPI 388
P P+ P P P PK PAP T + APT S + P P
Sbjct: 389 PAPTAPKKPAPTTPK-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP- 446
Query: 389 QIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPAD----A 444
+ + A +E + P +P+ P K + K P P A
Sbjct: 447 ---TTTKSAPTTPKEPSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPKEPAPTTPKEPA 500
Query: 445 PTVRATRASPDPRAYVPAKELLKPEADPR------PCERAPRGPAGPAAQQAAKLFGLEP 498
PT A P+ P P+ P + AP P PA +L P
Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 560
Query: 499 GRPPPTGPE 507
P PT PE
Sbjct: 561 EEPTPTTPE 569
Score = 38.1 bits (87), Expect = 0.13
Identities = 35/157 (22%), Positives = 61/157 (38%), Gaps = 20/157 (12%)
Query: 2344 RAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAF 2403
+ TL+ +V +T + + + +P D+ + P P +P+ AP
Sbjct: 879 KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKP 938
Query: 2404 TSCPAPEPFAELPAPATSLAPAPLI-TMPATRPKPKKARAAEESGAKGPRRPGEEAELLV 2462
TS P+ + P T+ P + TMP P + A A ++ + + P + LV
Sbjct: 939 TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK---LV 995
Query: 2463 KLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLL 2499
++ +PKS ED G + P LL
Sbjct: 996 EV------NPKS----------EDAGGAEGETPHMLL 1016
Score = 36.6 bits (83), Expect = 0.38
Identities = 52/215 (24%), Positives = 76/215 (35%), Gaps = 36/215 (16%)
Query: 2288 CAEPSPALLVPSA----KRRSRKTSKDTGEGKDGGTAGS--EEPGAKARGRGRKPSAK-- 2339
C +P+P +A K + T K+ GTA + +EP A +KP+ K
Sbjct: 653 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP---APTTPKKPAPKEL 709
Query: 2340 ----AKGDRAATLEEGNPT---DEVPSTPLALEPSSTPGSKKSP-----PEPVDKRAKAP 2387
KG + T ++ PT + P+TP EP+ T K +P P P P
Sbjct: 710 APTTTKGPTSTTSDKPAPTTPKETAPTTPK--EPAPTTPKKPAPTTPETPPPTTSEVSTP 767
Query: 2388 KARPAP----PQPSPAPPAFTSCPAPEPFAELP-APATSLAPAPLITMP--ATRPKPKKA 2440
P P + P ++ P P+ P P P T P T K K
Sbjct: 768 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT 827
Query: 2441 ----RAAEESGAKGPRRPGEEAELLVKLDHEGVTS 2471
R E+ P+ E A K +T+
Sbjct: 828 ERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 862
Score = 35.0 bits (79), Expect = 1.1
Identities = 46/194 (23%), Positives = 61/194 (31%), Gaps = 19/194 (9%)
Query: 332 PSPLPPPPAPPKGPPAPPAATP-AGVYTVFREQG----REHRVVAP------TFVPSVEA 380
P+P P A P P P TP T +E +E P T
Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 630
Query: 381 FDERPGPIQIA-SQARDARAREREAGRP----GVLQAPPGSPRPL--DRPEGLREKNSVI 433
++P P ++A + ++ + + P G P P P P K +
Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 690
Query: 434 RSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKL 493
+LK P P P A + P A P E AP P PA K
Sbjct: 691 TTLKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 749
Query: 494 FGLEPGRPPPTGPE 507
P PPPT E
Sbjct: 750 APTTPETPPPTTSE 763
Score = 34.7 bits (78), Expect = 1.4
Identities = 102/532 (19%), Positives = 148/532 (27%), Gaps = 46/532 (8%)
Query: 4 RDFGPQRSVHGPPPP----LLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLH 59
+D P V P P G A+ + + T + PAS P P +
Sbjct: 226 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 285
Query: 60 PHPGEAFLGSFVASGMGPSASSHGSPVPL----PSDLSFRSPTPSNLPMVQLWAAHAHEG 115
P S + P+ ++ P P P+ + + P P+
Sbjct: 286 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345
Query: 116 FSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGS 175
P+ P P + P + +P+ T K P P AP +
Sbjct: 346 TPKKPAPTTPK-----EPAPTTPKEPTPTTPKEPA--PTTKEPAPT-----TPKEPAPTA 393
Query: 176 LHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGP 235
AP+ + PA ++ P + EP P K P E A
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK-----EPAPTTTKSAPTTTKEPAPTT 448
Query: 236 RGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPA 295
T + + P + +P + +P+ T PA
Sbjct: 449 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 508
Query: 296 LVA--EAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATP 353
E KE A E L P P+P P P P P TP
Sbjct: 509 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 568
Query: 354 AGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAP 413
+ + P E P + ++ + P L+ P
Sbjct: 569 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTTLKEP 627
Query: 414 ----PGSPRPLD-RPEGLREKNSVIRSLKRP--PPADAPTVRATRASPDPRAYVP----- 461
P P P + P +E S P P APT A P+ P
Sbjct: 628 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 687
Query: 462 -AKELLKPEA-----DPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPE 507
A LK A P P E AP GP + + K P PT P+
Sbjct: 688 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 739
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 76.3 bits (186), Expect = 4e-13
Identities = 94/453 (20%), Positives = 162/453 (35%), Gaps = 46/453 (10%)
Query: 2353 PTDEVPSTPLALEPSSTPGSKKSPPE---PVDKRAKAPKA--RPAPPQPSPAPPAFTSCP 2407
P P+TP L P++ + PE P +A AP PAP P P P
Sbjct: 596 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 655
Query: 2408 APEPFAEL---------------PAPATSLAPAPLITMPATRPKPKKAR----AAEESGA 2448
AP E PAP T PAP P T +P A
Sbjct: 656 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 715
Query: 2449 KGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRED-PGAGGWQEPKSLLSLGSYPPA 2507
P P E A K +P + K L+E P PK L + P
Sbjct: 716 TAPTTPKEPAPTTPK-----EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 770
Query: 2508 AGSSEPKAP-WPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSG 2566
+ +S+ AP PK T +EP P PK P E SE S+ +++
Sbjct: 771 STTSDKPAPTTPKETAPTTPKEPAP-------TTPKKPAPTTPETPPPTTSEVSTPTTTK 823
Query: 2567 SSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSS 2626
++ S + E K + G + AA+ ++++ ++
Sbjct: 824 EPTTIHKSPDESTPELSAEPTPKALENSPKEPG--VPTTKTPAATKPEMTTTAKDKTTER 881
Query: 2627 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAA 2686
++ +++++ + +++++ ++ S +++++ +S+++ TT + A
Sbjct: 882 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 941
Query: 2687 PAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAK 2746
P T K A+P + K P+PQ P P +P K K
Sbjct: 942 PKVTTTKKTITTTEI-MNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK---PK 997
Query: 2747 SRPKKREGVHLPTTKELAKRQRLPSVENRPKIA 2779
+ P+ R+ PT +++ +P + +IA
Sbjct: 998 TMPRVRKPKTTPTPRKMT--STMPELNPTSRIA 1028
Score = 69.7 bits (169), Expect = 4e-11
Identities = 99/444 (22%), Positives = 157/444 (35%), Gaps = 53/444 (11%)
Query: 2335 KPSAKA----KGDRAATLEEGNPT------DEVPSTPLALEPSSTPGSKKSPPEPVDKRA 2384
KP+ KA KG T +E PT P P S P + K P K
Sbjct: 289 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK-- 346
Query: 2385 KAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAE 2444
AP P P T PAP E PAP T+ PAP T A P K A
Sbjct: 347 ------SAPTTPKEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSA--PTTPKEPAPT 397
Query: 2445 ESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSY 2504
P P E A K P KE ++P +EP +
Sbjct: 398 TPKKPAPTTPKEPAPTTPK-------EPTPTTPKEPAPTTKEPAPTTPKEPAP-----TA 445
Query: 2505 PPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSS 2564
P + PK P P +EP P T E S P +P K A ++ +
Sbjct: 446 PKKPAPTTPKEPAPTT-----PKEPAPTTTKEPS--PTTP-KEPAPTTTKSAPTTTKEPA 497
Query: 2565 SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSS 2624
++ S+ ++ S T +E T + + + + +P ++ + +
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP---TTPKEPAPT 554
Query: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDE 2684
++ + ++ + ++ ++ ++ + ++ + ++ + TT E+ + ++ +E
Sbjct: 555 TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 614
Query: 2685 AAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAP----QPQAPPPQPTQPLQPK 2740
P PT P A KA P+ +P K PAP +P P+ T P PK
Sbjct: 615 --PTPTT-PEEPAPTTPKAAAPNTPKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPK 669
Query: 2741 AQAGAKSRPKKREGVHLPTTKELA 2764
A + P KELA
Sbjct: 670 GTAPTTLKEPAPTTPKKPAPKELA 693
Score = 54.3 bits (129), Expect = 2e-06
Identities = 87/367 (23%), Positives = 122/367 (33%), Gaps = 40/367 (10%)
Query: 972 PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSH 1030
P+KP P PA T K +P + SP K PA P T S
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP-------------KEPA---PTTTKSA 489
Query: 1031 PTSPPPASPPPTPG--ITRKEEAPENVVEKKDLELEKEAPS----PFQALFSDIPPRYPF 1084
PT+ +P T T KE +P E ++ AP+ P + P P
Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 549
Query: 1085 QALPPHYGRPYPFLLQPTAAADADGLAPDVP--LPADGPERLALSPEDKPI-----RLSP 1137
+ P +P P + A AP P L PE+LA + +KP L+P
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 609
Query: 1138 SKITEPLREGPEEEPLAEREVKAEVEDMDEGPT---ELPPLESPLPLPAAEAMATPSPAG 1194
+ EP PEE + A + PT E P P P P+
Sbjct: 610 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 669
Query: 1195 GCGGGLLEAQALSATGQSCAEPSECPDFVEGP-EPRVDSPGRTEPCTAALDLGVQLTPET 1253
G L+ A T + A P + P D P T P A + P T
Sbjct: 670 GTAPTTLKEPA-PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 728
Query: 1254 LVEAKEEPVEVPVAVPVVEAVP----EEGLAQVAPSESQ-PTLEMSDCDVPAGEGQCPSL 1308
E + + E P + ++AP+ ++ PT SD P +
Sbjct: 729 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788
Query: 1309 EPQEAVP 1315
P+E P
Sbjct: 789 TPKEPAP 795
Score = 51.6 bits (122), Expect = 1e-05
Identities = 69/308 (22%), Positives = 118/308 (38%), Gaps = 61/308 (19%)
Query: 2506 PAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQA----------EQDGAE 2555
P + S KAP P + +PK P+K + E+
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTT--------KRSPKPPNKKKTKKVIESEEITEEHSVS 120
Query: 2556 ESESSSSSSSGSSSSSS-----SSSSSGSETEGEEE------------------------ 2586
E++ SSSSSS SSSSS+ SS +S + E +++
Sbjct: 121 ENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDE 180
Query: 2587 ---GDKNGDGGCGTGGRNCSAASSRAASPASSSSS------SSSSSSSSSSSSSSSSSSS 2637
G NGD T + + + + SP +++ S +S +S +S + +
Sbjct: 181 AGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKE 240
Query: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQA 2697
++ + +++++ +S+ ++S+ + S T+ +D + +S A P P A + +
Sbjct: 241 TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 300
Query: 2698 ALPTKATKQAGKARPSAHSPGKKTP-APQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVH 2756
T K+ P P TP P P PT P +P A KS P +
Sbjct: 301 PALT-TPKEPTPTTPK--EPASTTPKEPTPTTIKSAPTTPKEP-APTTTKSAPTTPKEPA 356
Query: 2757 LPTTKELA 2764
TTKE A
Sbjct: 357 PTTTKEPA 364
Score = 48.9 bits (115), Expect = 7e-05
Identities = 78/339 (23%), Positives = 108/339 (31%), Gaps = 28/339 (8%)
Query: 972 PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSH 1030
P++P P PA T K +P + +P A K E P P TP
Sbjct: 352 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPTTPKKPAPTTPKEP 410
Query: 1031 -PTSPPPASP--PPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQAL 1087
PT+P +P P P T KE AP E +K AP+ + + P P +
Sbjct: 411 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK----EPAPTTPKEPA 466
Query: 1088 PPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREG 1147
P P P + A PA + A + +P SP+ EP
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP---SPTTTKEPAPTT 523
Query: 1148 PEEEPLAEREVKAEVEDMDEGP-TELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQAL 1206
P+E + A + P T P + PA P+P + L
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 583
Query: 1207 SATGQSCAEPSE------------CPDFVEGPEPRV-DSPGRTEPCTAALDLGVQLTPET 1253
+ T P+ P E P P + P T P AA + + P T
Sbjct: 584 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 643
Query: 1254 LVEAKEEPVEVPVAVPVVEAVP--EEGLAQVAPSESQPT 1290
E + P E P +G A E PT
Sbjct: 644 PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682
Score = 48.1 bits (113), Expect = 1e-04
Identities = 70/328 (21%), Positives = 102/328 (31%), Gaps = 39/328 (11%)
Query: 973 RKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPS--- 1028
+KP P PA T K +P + +P K + P P TP
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616
Query: 1029 -SHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIP----PRYP 1083
+ P P P +P T KE AP E ++ AP+ + P P
Sbjct: 617 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 676
Query: 1084 FQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPED------------K 1131
+ P +P P L PT + D P P +P++
Sbjct: 677 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 736
Query: 1132 PIRLSPSKITEPLREGPEE---EPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMA 1188
P +P+ + EP P++ + LA K + P P E+ P A
Sbjct: 737 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 796
Query: 1189 TPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQ 1248
TP A T P + P SP + P +L +
Sbjct: 797 TPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP-----ELSAE 842
Query: 1249 LTPETLVEAKEEPVEVPVAVPVVEAVPE 1276
TP+ L + +EP VP PE
Sbjct: 843 PTPKALENSPKEP-GVPTTKTPAATKPE 869
Score = 46.6 bits (109), Expect = 4e-04
Identities = 84/358 (23%), Positives = 114/358 (31%), Gaps = 59/358 (16%)
Query: 960 KAGLATAGPGLL-PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSK 1017
KA T GP L P++P P PA T K +P I+ K
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPT--------------TIKSAPTTPK 338
Query: 1018 PPAYAYPATPSSHPTSP--------------PPASPPPT----PGITRKEEAPENVVEKK 1059
PA P T S PT+P P P PT P T + AP E
Sbjct: 339 EPA---PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 395
Query: 1060 DLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQ--PTAAADADGLAPDVPLP 1117
+K AP+ + + P P + P P P + PT + AP P P
Sbjct: 396 PTTPKKPAPTTPK----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 1118 ADGPERLALSPEDKPIRL----SPSKITEPLREGPEEEPLAERE-VKAEVEDMDEGPTEL 1172
E +P++ SP+ EP + P +E + P E
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 1173 PPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDS 1232
P + P P P+ + A + + ++ P EP +
Sbjct: 512 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 571
Query: 1233 PGRTEPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPT 1290
P T P T +LTP T + E P PEE LA P E PT
Sbjct: 572 PKETAPTTPK-----KLTPTTPEKLAPTTPEKP-----APTTPEE-LAPTTPEEPTPT 618
Score = 46.6 bits (109), Expect = 4e-04
Identities = 42/174 (24%), Positives = 65/174 (37%), Gaps = 11/174 (6%)
Query: 2290 EPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKA-KGDRAATL 2348
+P+P L P+ + T+ D P A ++P+ KG TL
Sbjct: 686 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 745
Query: 2349 EEGNPTDEVPSTPLALEPSSTPG---SKKSPPEPVDKRAKAPKARPAPPQPSPA---PPA 2402
+E PT P L P++T G + P P + AP P +P+P PA
Sbjct: 746 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT---PKEPAPTTPKKPA 802
Query: 2403 FTSCPAPEP-FAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPG 2455
T+ P P +E+ P T+ P + P A ++ P+ PG
Sbjct: 803 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 856
Score = 45.4 bits (106), Expect = 8e-04
Identities = 73/312 (23%), Positives = 99/312 (31%), Gaps = 34/312 (10%)
Query: 999 SPVAALKAKVIQKLEDVSKPPAYAYPATPS----SHPTSPPPASPPPTP----GITRKEE 1050
+P + + AK K E +K PA P P+ P S P P PT T KE
Sbjct: 281 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340
Query: 1051 APENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQ--PTAAADAD 1108
AP K + P+P + P P + P P P + PT +
Sbjct: 341 APTTT---KSAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 395
Query: 1109 GLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAERE-----VKAEVE 1163
P P P E +P++ +P+ EP E P +E K
Sbjct: 396 PTTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 1164 DMDEGPTELPPLESPLPLPAAEAMAT----PSPAGGCGGGLLEAQALSATGQSCAEPSEC 1219
+ P P E P P E T P+P + T +S +
Sbjct: 452 TTPKEPAPTTPKE-PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 510
Query: 1220 PDFVEGPEPRVDSPGRTEPCTAALDLGVQLTP-ETLVEAKEEPVEVPVAVPVVEAVPEEG 1278
P EP +P EP TP E +EP P P+E
Sbjct: 511 PSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP-APTTPKEP 567
Query: 1279 LAQVAPSESQPT 1290
A P E+ PT
Sbjct: 568 -APTTPKETAPT 578
Score = 45.1 bits (105), Expect = 0.001
Identities = 74/420 (17%), Positives = 140/420 (33%), Gaps = 43/420 (10%)
Query: 2368 STPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPL 2427
+TP + + V K A+P P+PS P + TS TSL
Sbjct: 193 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS------------KETSLTVNKE 240
Query: 2428 ITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDP 2487
T+ + + + K +E + + K TS K +L + P
Sbjct: 241 TTVETKETTTTNKQTSTDGKEK--TTSAKETQSIEK------TSAKDLAPTSKVLAKPTP 292
Query: 2488 GAGGWQEPKSLLS----LGSYPPAAGSSEPKAPWPKATDG--DLAQEPGPGLTFEDSGNP 2541
A + +L + + P S+ PK P P +EP P T P
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 352
Query: 2542 KSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRN 2601
K P ++ + + +++ + +++ S+ + E K
Sbjct: 353 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK----------- 401
Query: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
A + PA ++ + ++ + ++ + ++ + ++ + ++ +
Sbjct: 402 --PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 459
Query: 2662 SSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
++ + TT ++ S ++ E AP T P T ++ P SP T
Sbjct: 460 TTPKEPAP--TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP-TTT 516
Query: 2722 PAPQPQAPP-PQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAA 2780
P P P P PT P +P + P + TTK+ A PK A
Sbjct: 517 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576
Score = 40.4 bits (93), Expect = 0.026
Identities = 46/189 (24%), Positives = 60/189 (31%), Gaps = 19/189 (10%)
Query: 330 PCPS-PLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPI 388
P P+ P P P PK PAP T + APT S + P P
Sbjct: 441 PAPTAPKKPAPTTPK-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP- 498
Query: 389 QIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPAD----A 444
+ + A +E + P +P+ P K + K P P A
Sbjct: 499 ---TTTKSAPTTPKEPSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPKEPAPTTPKEPA 552
Query: 445 PTVRATRASPDPRAYVPAKELLKPEADPR------PCERAPRGPAGPAAQQAAKLFGLEP 498
PT A P+ P P+ P + AP P PA +L P
Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 612
Query: 499 GRPPPTGPE 507
P PT PE
Sbjct: 613 EEPTPTTPE 621
Score = 38.1 bits (87), Expect = 0.13
Identities = 35/157 (22%), Positives = 61/157 (38%), Gaps = 20/157 (12%)
Query: 2344 RAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAF 2403
+ TL+ +V +T + + + +P D+ + P P +P+ AP
Sbjct: 931 KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKP 990
Query: 2404 TSCPAPEPFAELPAPATSLAPAPLI-TMPATRPKPKKARAAEESGAKGPRRPGEEAELLV 2462
TS P+ + P T+ P + TMP P + A A ++ + + P + LV
Sbjct: 991 TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK---LV 1047
Query: 2463 KLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLL 2499
++ +PKS ED G + P LL
Sbjct: 1048 EV------NPKS----------EDAGGAEGETPHMLL 1068
Score = 36.6 bits (83), Expect = 0.38
Identities = 52/215 (24%), Positives = 76/215 (35%), Gaps = 36/215 (16%)
Query: 2288 CAEPSPALLVPSA----KRRSRKTSKDTGEGKDGGTAGS--EEPGAKARGRGRKPSAK-- 2339
C +P+P +A K + T K+ GTA + +EP A +KP+ K
Sbjct: 705 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP---APTTPKKPAPKEL 761
Query: 2340 ----AKGDRAATLEEGNPT---DEVPSTPLALEPSSTPGSKKSP-----PEPVDKRAKAP 2387
KG + T ++ PT + P+TP EP+ T K +P P P P
Sbjct: 762 APTTTKGPTSTTSDKPAPTTPKETAPTTPK--EPAPTTPKKPAPTTPETPPPTTSEVSTP 819
Query: 2388 KARPAP----PQPSPAPPAFTSCPAPEPFAELP-APATSLAPAPLITMP--ATRPKPKKA 2440
P P + P ++ P P+ P P P T P T K K
Sbjct: 820 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT 879
Query: 2441 ----RAAEESGAKGPRRPGEEAELLVKLDHEGVTS 2471
R E+ P+ E A K +T+
Sbjct: 880 ERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 914
Score = 35.8 bits (81), Expect = 0.65
Identities = 30/125 (24%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
Query: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
C+ + + P+S + S +S + S++ S + + S + S S +
Sbjct: 63 CAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSEN 122
Query: 2662 SSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
SSSSSSSS++ SS +++ A Q L K K+ + KK
Sbjct: 123 QESSSSSSSSSS---SSTIRKIKSSKNSAANRELQKKLKVKDNKK---------NRTKKK 170
Query: 2722 PAPQP 2726
P P+P
Sbjct: 171 PTPKP 175
Score = 35.0 bits (79), Expect = 1.1
Identities = 46/194 (23%), Positives = 61/194 (31%), Gaps = 19/194 (9%)
Query: 332 PSPLPPPPAPPKGPPAPPAATP-AGVYTVFREQG----REHRVVAP------TFVPSVEA 380
P+P P A P P P TP T +E +E P T
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682
Query: 381 FDERPGPIQIA-SQARDARAREREAGRP----GVLQAPPGSPRPL--DRPEGLREKNSVI 433
++P P ++A + ++ + + P G P P P P K +
Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 742
Query: 434 RSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKL 493
+LK P P P A + P A P E AP P PA K
Sbjct: 743 TTLKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 801
Query: 494 FGLEPGRPPPTGPE 507
P PPPT E
Sbjct: 802 APTTPETPPPTTSE 815
Score = 34.7 bits (78), Expect = 1.4
Identities = 102/532 (19%), Positives = 148/532 (27%), Gaps = 46/532 (8%)
Query: 4 RDFGPQRSVHGPPPP----LLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLH 59
+D P V P P G A+ + + T + PAS P P +
Sbjct: 278 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 337
Query: 60 PHPGEAFLGSFVASGMGPSASSHGSPVPL----PSDLSFRSPTPSNLPMVQLWAAHAHEG 115
P S + P+ ++ P P P+ + + P P+
Sbjct: 338 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397
Query: 116 FSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGS 175
P+ P P + P + +P+ T K P P AP +
Sbjct: 398 TPKKPAPTTPK-----EPAPTTPKEPTPTTPKEPA--PTTKEPAPT-----TPKEPAPTA 445
Query: 176 LHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGP 235
AP+ + PA ++ P + EP P K P E A
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK-----EPAPTTTKSAPTTTKEPAPTT 500
Query: 236 RGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPA 295
T + + P + +P + +P+ T PA
Sbjct: 501 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 560
Query: 296 LVA--EAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATP 353
E KE A E L P P+P P P P P TP
Sbjct: 561 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 620
Query: 354 AGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAP 413
+ + P E P + ++ + P L+ P
Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTTLKEP 679
Query: 414 ----PGSPRPLD-RPEGLREKNSVIRSLKRP--PPADAPTVRATRASPDPRAYVP----- 461
P P P + P +E S P P APT A P+ P
Sbjct: 680 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 739
Query: 462 -AKELLKPEA-----DPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPE 507
A LK A P P E AP GP + + K P PT P+
Sbjct: 740 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 791
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 76.3 bits (186), Expect = 4e-13
Identities = 94/453 (20%), Positives = 162/453 (35%), Gaps = 46/453 (10%)
Query: 2353 PTDEVPSTPLALEPSSTPGSKKSPPE---PVDKRAKAPKA--RPAPPQPSPAPPAFTSCP 2407
P P+TP L P++ + PE P +A AP PAP P P P
Sbjct: 637 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 696
Query: 2408 APEPFAEL---------------PAPATSLAPAPLITMPATRPKPKKAR----AAEESGA 2448
AP E PAP T PAP P T +P A
Sbjct: 697 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 756
Query: 2449 KGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRED-PGAGGWQEPKSLLSLGSYPPA 2507
P P E A K +P + K L+E P PK L + P
Sbjct: 757 TAPTTPKEPAPTTPK-----EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 811
Query: 2508 AGSSEPKAP-WPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSG 2566
+ +S+ AP PK T +EP P PK P E SE S+ +++
Sbjct: 812 STTSDKPAPTTPKETAPTTPKEPAP-------TTPKKPAPTTPETPPPTTSEVSTPTTTK 864
Query: 2567 SSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSS 2626
++ S + E K + G + AA+ ++++ ++
Sbjct: 865 EPTTIHKSPDESTPELSAEPTPKALENSPKEPG--VPTTKTPAATKPEMTTTAKDKTTER 922
Query: 2627 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAA 2686
++ +++++ + +++++ ++ S +++++ +S+++ TT + A
Sbjct: 923 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 982
Query: 2687 PAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAK 2746
P T K A+P + K P+PQ P P +P K K
Sbjct: 983 PKVTTTKKTITTTEI-MNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK---PK 1038
Query: 2747 SRPKKREGVHLPTTKELAKRQRLPSVENRPKIA 2779
+ P+ R+ PT +++ +P + +IA
Sbjct: 1039 TMPRVRKPKTTPTPRKMT--STMPELNPTSRIA 1069
Score = 69.7 bits (169), Expect = 4e-11
Identities = 99/444 (22%), Positives = 157/444 (35%), Gaps = 53/444 (11%)
Query: 2335 KPSAKA----KGDRAATLEEGNPT------DEVPSTPLALEPSSTPGSKKSPPEPVDKRA 2384
KP+ KA KG T +E PT P P S P + K P K
Sbjct: 330 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK-- 387
Query: 2385 KAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAE 2444
AP P P T PAP E PAP T+ PAP T A P K A
Sbjct: 388 ------SAPTTPKEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSA--PTTPKEPAPT 438
Query: 2445 ESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSY 2504
P P E A K P KE ++P +EP +
Sbjct: 439 TPKKPAPTTPKEPAPTTPK-------EPTPTTPKEPAPTTKEPAPTTPKEPAP-----TA 486
Query: 2505 PPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSS 2564
P + PK P P +EP P T E S P +P K A ++ +
Sbjct: 487 PKKPAPTTPKEPAPTT-----PKEPAPTTTKEPS--PTTP-KEPAPTTTKSAPTTTKEPA 538
Query: 2565 SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSS 2624
++ S+ ++ S T +E T + + + + +P ++ + +
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP---TTPKEPAPT 595
Query: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDE 2684
++ + ++ + ++ ++ ++ + ++ + ++ + TT E+ + ++ +E
Sbjct: 596 TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 655
Query: 2685 AAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAP----QPQAPPPQPTQPLQPK 2740
P PT P A KA P+ +P K PAP +P P+ T P PK
Sbjct: 656 --PTPTT-PEEPAPTTPKAAAPNTPKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPK 710
Query: 2741 AQAGAKSRPKKREGVHLPTTKELA 2764
A + P KELA
Sbjct: 711 GTAPTTLKEPAPTTPKKPAPKELA 734
Score = 54.3 bits (129), Expect = 2e-06
Identities = 87/367 (23%), Positives = 122/367 (33%), Gaps = 40/367 (10%)
Query: 972 PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSH 1030
P+KP P PA T K +P + SP K PA P T S
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP-------------KEPA---PTTTKSA 530
Query: 1031 PTSPPPASPPPTPG--ITRKEEAPENVVEKKDLELEKEAPS----PFQALFSDIPPRYPF 1084
PT+ +P T T KE +P E ++ AP+ P + P P
Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 590
Query: 1085 QALPPHYGRPYPFLLQPTAAADADGLAPDVP--LPADGPERLALSPEDKPI-----RLSP 1137
+ P +P P + A AP P L PE+LA + +KP L+P
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 650
Query: 1138 SKITEPLREGPEEEPLAEREVKAEVEDMDEGPT---ELPPLESPLPLPAAEAMATPSPAG 1194
+ EP PEE + A + PT E P P P P+
Sbjct: 651 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 710
Query: 1195 GCGGGLLEAQALSATGQSCAEPSECPDFVEGP-EPRVDSPGRTEPCTAALDLGVQLTPET 1253
G L+ A T + A P + P D P T P A + P T
Sbjct: 711 GTAPTTLKEPA-PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 769
Query: 1254 LVEAKEEPVEVPVAVPVVEAVP----EEGLAQVAPSESQ-PTLEMSDCDVPAGEGQCPSL 1308
E + + E P + ++AP+ ++ PT SD P +
Sbjct: 770 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829
Query: 1309 EPQEAVP 1315
P+E P
Sbjct: 830 TPKEPAP 836
Score = 51.6 bits (122), Expect = 1e-05
Identities = 69/308 (22%), Positives = 118/308 (38%), Gaps = 61/308 (19%)
Query: 2506 PAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQA----------EQDGAE 2555
P + S KAP P + +PK P+K + E+
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTT--------KRSPKPPNKKKTKKVIESEEITEEHSVS 161
Query: 2556 ESESSSSSSSGSSSSSS-----SSSSSGSETEGEEE------------------------ 2586
E++ SSSSSS SSSSS+ SS +S + E +++
Sbjct: 162 ENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDE 221
Query: 2587 ---GDKNGDGGCGTGGRNCSAASSRAASPASSSSS------SSSSSSSSSSSSSSSSSSS 2637
G NGD T + + + + SP +++ S +S +S +S + +
Sbjct: 222 AGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKE 281
Query: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQA 2697
++ + +++++ +S+ ++S+ + S T+ +D + +S A P P A + +
Sbjct: 282 TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 341
Query: 2698 ALPTKATKQAGKARPSAHSPGKKTP-APQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVH 2756
T K+ P P TP P P PT P +P A KS P +
Sbjct: 342 PALT-TPKEPTPTTPK--EPASTTPKEPTPTTIKSAPTTPKEP-APTTTKSAPTTPKEPA 397
Query: 2757 LPTTKELA 2764
TTKE A
Sbjct: 398 PTTTKEPA 405
Score = 48.9 bits (115), Expect = 7e-05
Identities = 78/339 (23%), Positives = 108/339 (31%), Gaps = 28/339 (8%)
Query: 972 PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSH 1030
P++P P PA T K +P + +P A K E P P TP
Sbjct: 393 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPTTPKKPAPTTPKEP 451
Query: 1031 -PTSPPPASP--PPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQAL 1087
PT+P +P P P T KE AP E +K AP+ + + P P +
Sbjct: 452 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK----EPAPTTPKEPA 507
Query: 1088 PPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREG 1147
P P P + A PA + A + +P SP+ EP
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP---SPTTTKEPAPTT 564
Query: 1148 PEEEPLAEREVKAEVEDMDEGP-TELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQAL 1206
P+E + A + P T P + PA P+P + L
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 624
Query: 1207 SATGQSCAEPSE------------CPDFVEGPEPRV-DSPGRTEPCTAALDLGVQLTPET 1253
+ T P+ P E P P + P T P AA + + P T
Sbjct: 625 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 684
Query: 1254 LVEAKEEPVEVPVAVPVVEAVP--EEGLAQVAPSESQPT 1290
E + P E P +G A E PT
Sbjct: 685 PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723
Score = 48.1 bits (113), Expect = 1e-04
Identities = 70/328 (21%), Positives = 102/328 (31%), Gaps = 39/328 (11%)
Query: 973 RKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPS--- 1028
+KP P PA T K +P + +P K + P P TP
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657
Query: 1029 -SHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIP----PRYP 1083
+ P P P +P T KE AP E ++ AP+ + P P
Sbjct: 658 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 717
Query: 1084 FQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPED------------K 1131
+ P +P P L PT + D P P +P++
Sbjct: 718 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 777
Query: 1132 PIRLSPSKITEPLREGPEE---EPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMA 1188
P +P+ + EP P++ + LA K + P P E+ P A
Sbjct: 778 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 837
Query: 1189 TPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQ 1248
TP A T P + P SP + P +L +
Sbjct: 838 TPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP-----ELSAE 883
Query: 1249 LTPETLVEAKEEPVEVPVAVPVVEAVPE 1276
TP+ L + +EP VP PE
Sbjct: 884 PTPKALENSPKEP-GVPTTKTPAATKPE 910
Score = 46.6 bits (109), Expect = 4e-04
Identities = 84/358 (23%), Positives = 114/358 (31%), Gaps = 59/358 (16%)
Query: 960 KAGLATAGPGLL-PRKP-PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSK 1017
KA T GP L P++P P PA T K +P I+ K
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPT--------------TIKSAPTTPK 379
Query: 1018 PPAYAYPATPSSHPTSP--------------PPASPPPT----PGITRKEEAPENVVEKK 1059
PA P T S PT+P P P PT P T + AP E
Sbjct: 380 EPA---PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 436
Query: 1060 DLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQ--PTAAADADGLAPDVPLP 1117
+K AP+ + + P P + P P P + PT + AP P P
Sbjct: 437 PTTPKKPAPTTPK----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 1118 ADGPERLALSPEDKPIRL----SPSKITEPLREGPEEEPLAERE-VKAEVEDMDEGPTEL 1172
E +P++ SP+ EP + P +E + P E
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 1173 PPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDS 1232
P + P P P+ + A + + ++ P EP +
Sbjct: 553 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 612
Query: 1233 PGRTEPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPT 1290
P T P T +LTP T + E P PEE LA P E PT
Sbjct: 613 PKETAPTTPK-----KLTPTTPEKLAPTTPEKP-----APTTPEE-LAPTTPEEPTPT 659
Score = 46.6 bits (109), Expect = 4e-04
Identities = 42/174 (24%), Positives = 65/174 (37%), Gaps = 11/174 (6%)
Query: 2290 EPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKA-KGDRAATL 2348
+P+P L P+ + T+ D P A ++P+ KG TL
Sbjct: 727 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 786
Query: 2349 EEGNPTDEVPSTPLALEPSSTPG---SKKSPPEPVDKRAKAPKARPAPPQPSPA---PPA 2402
+E PT P L P++T G + P P + AP P +P+P PA
Sbjct: 787 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT---PKEPAPTTPKKPA 843
Query: 2403 FTSCPAPEP-FAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPG 2455
T+ P P +E+ P T+ P + P A ++ P+ PG
Sbjct: 844 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 897
Score = 45.4 bits (106), Expect = 8e-04
Identities = 73/312 (23%), Positives = 99/312 (31%), Gaps = 34/312 (10%)
Query: 999 SPVAALKAKVIQKLEDVSKPPAYAYPATPS----SHPTSPPPASPPPTP----GITRKEE 1050
+P + + AK K E +K PA P P+ P S P P PT T KE
Sbjct: 322 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381
Query: 1051 APENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQ--PTAAADAD 1108
AP K + P+P + P P + P P P + PT +
Sbjct: 382 APTTT---KSAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 436
Query: 1109 GLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAERE-----VKAEVE 1163
P P P E +P++ +P+ EP E P +E K
Sbjct: 437 PTTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 1164 DMDEGPTELPPLESPLPLPAAEAMAT----PSPAGGCGGGLLEAQALSATGQSCAEPSEC 1219
+ P P E P P E T P+P + T +S +
Sbjct: 493 TTPKEPAPTTPKE-PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 551
Query: 1220 PDFVEGPEPRVDSPGRTEPCTAALDLGVQLTP-ETLVEAKEEPVEVPVAVPVVEAVPEEG 1278
P EP +P EP TP E +EP P P+E
Sbjct: 552 PSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP-APTTPKEP 608
Query: 1279 LAQVAPSESQPT 1290
A P E+ PT
Sbjct: 609 -APTTPKETAPT 619
Score = 45.1 bits (105), Expect = 0.001
Identities = 74/420 (17%), Positives = 140/420 (33%), Gaps = 43/420 (10%)
Query: 2368 STPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPL 2427
+TP + + V K A+P P+PS P + TS TSL
Sbjct: 234 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS------------KETSLTVNKE 281
Query: 2428 ITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDP 2487
T+ + + + K +E + + K TS K +L + P
Sbjct: 282 TTVETKETTTTNKQTSTDGKEK--TTSAKETQSIEK------TSAKDLAPTSKVLAKPTP 333
Query: 2488 GAGGWQEPKSLLS----LGSYPPAAGSSEPKAPWPKATDG--DLAQEPGPGLTFEDSGNP 2541
A + +L + + P S+ PK P P +EP P T P
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 393
Query: 2542 KSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRN 2601
K P ++ + + +++ + +++ S+ + E K
Sbjct: 394 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK----------- 442
Query: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
A + PA ++ + ++ + ++ + ++ + ++ + ++ +
Sbjct: 443 --PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 500
Query: 2662 SSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
++ + TT ++ S ++ E AP T P T ++ P SP T
Sbjct: 501 TTPKEPAP--TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP-TTT 557
Query: 2722 PAPQPQAPP-PQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAA 2780
P P P P PT P +P + P + TTK+ A PK A
Sbjct: 558 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617
Score = 40.4 bits (93), Expect = 0.026
Identities = 46/189 (24%), Positives = 60/189 (31%), Gaps = 19/189 (10%)
Query: 330 PCPS-PLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPI 388
P P+ P P P PK PAP T + APT S + P P
Sbjct: 482 PAPTAPKKPAPTTPK-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP- 539
Query: 389 QIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPAD----A 444
+ + A +E + P +P+ P K + K P P A
Sbjct: 540 ---TTTKSAPTTPKEPSPTTTKEPAPTTPK---EPAPTTPKKPAPTTPKEPAPTTPKEPA 593
Query: 445 PTVRATRASPDPRAYVPAKELLKPEADPR------PCERAPRGPAGPAAQQAAKLFGLEP 498
PT A P+ P P+ P + AP P PA +L P
Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 653
Query: 499 GRPPPTGPE 507
P PT PE
Sbjct: 654 EEPTPTTPE 662
Score = 38.1 bits (87), Expect = 0.13
Identities = 35/157 (22%), Positives = 61/157 (38%), Gaps = 20/157 (12%)
Query: 2344 RAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAF 2403
+ TL+ +V +T + + + +P D+ + P P +P+ AP
Sbjct: 972 KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKP 1031
Query: 2404 TSCPAPEPFAELPAPATSLAPAPLI-TMPATRPKPKKARAAEESGAKGPRRPGEEAELLV 2462
TS P+ + P T+ P + TMP P + A A ++ + + P + LV
Sbjct: 1032 TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK---LV 1088
Query: 2463 KLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLL 2499
++ +PKS ED G + P LL
Sbjct: 1089 EV------NPKS----------EDAGGAEGETPHMLL 1109
Score = 36.6 bits (83), Expect = 0.38
Identities = 52/215 (24%), Positives = 76/215 (35%), Gaps = 36/215 (16%)
Query: 2288 CAEPSPALLVPSA----KRRSRKTSKDTGEGKDGGTAGS--EEPGAKARGRGRKPSAK-- 2339
C +P+P +A K + T K+ GTA + +EP A +KP+ K
Sbjct: 746 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP---APTTPKKPAPKEL 802
Query: 2340 ----AKGDRAATLEEGNPT---DEVPSTPLALEPSSTPGSKKSP-----PEPVDKRAKAP 2387
KG + T ++ PT + P+TP EP+ T K +P P P P
Sbjct: 803 APTTTKGPTSTTSDKPAPTTPKETAPTTPK--EPAPTTPKKPAPTTPETPPPTTSEVSTP 860
Query: 2388 KARPAP----PQPSPAPPAFTSCPAPEPFAELP-APATSLAPAPLITMP--ATRPKPKKA 2440
P P + P ++ P P+ P P P T P T K K
Sbjct: 861 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT 920
Query: 2441 ----RAAEESGAKGPRRPGEEAELLVKLDHEGVTS 2471
R E+ P+ E A K +T+
Sbjct: 921 ERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 955
Score = 35.8 bits (81), Expect = 0.65
Identities = 30/125 (24%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
Query: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
C+ + + P+S + S +S + S++ S + + S + S S +
Sbjct: 104 CAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSEN 163
Query: 2662 SSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
SSSSSSSS++ SS +++ A Q L K K+ + KK
Sbjct: 164 QESSSSSSSSSS---SSTIRKIKSSKNSAANRELQKKLKVKDNKK---------NRTKKK 211
Query: 2722 PAPQP 2726
P P+P
Sbjct: 212 PTPKP 216
Score = 35.0 bits (79), Expect = 1.1
Identities = 46/194 (23%), Positives = 61/194 (31%), Gaps = 19/194 (9%)
Query: 332 PSPLPPPPAPPKGPPAPPAATP-AGVYTVFREQG----REHRVVAP------TFVPSVEA 380
P+P P A P P P TP T +E +E P T
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723
Query: 381 FDERPGPIQIA-SQARDARAREREAGRP----GVLQAPPGSPRPL--DRPEGLREKNSVI 433
++P P ++A + ++ + + P G P P P P K +
Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 783
Query: 434 RSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKL 493
+LK P P P A + P A P E AP P PA K
Sbjct: 784 TTLKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 842
Query: 494 FGLEPGRPPPTGPE 507
P PPPT E
Sbjct: 843 APTTPETPPPTTSE 856
Score = 34.7 bits (78), Expect = 1.4
Identities = 102/532 (19%), Positives = 148/532 (27%), Gaps = 46/532 (8%)
Query: 4 RDFGPQRSVHGPPPP----LLSGLAMDSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLH 59
+D P V P P G A+ + + T + PAS P P +
Sbjct: 319 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 378
Query: 60 PHPGEAFLGSFVASGMGPSASSHGSPVPL----PSDLSFRSPTPSNLPMVQLWAAHAHEG 115
P S + P+ ++ P P P+ + + P P+
Sbjct: 379 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438
Query: 116 FSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGS 175
P+ P P + P + +P+ T K P P AP +
Sbjct: 439 TPKKPAPTTPK-----EPAPTTPKEPTPTTPKEPA--PTTKEPAPT-----TPKEPAPTA 486
Query: 176 LHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGP 235
AP+ + PA ++ P + EP P K P E A
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK-----EPAPTTTKSAPTTTKEPAPTT 541
Query: 236 RGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPA 295
T + + P + +P + +P+ T PA
Sbjct: 542 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 601
Query: 296 LVA--EAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATP 353
E KE A E L P P+P P P P P TP
Sbjct: 602 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 661
Query: 354 AGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAP 413
+ + P E P + ++ + P L+ P
Sbjct: 662 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTTLKEP 720
Query: 414 ----PGSPRPLD-RPEGLREKNSVIRSLKRP--PPADAPTVRATRASPDPRAYVP----- 461
P P P + P +E S P P APT A P+ P
Sbjct: 721 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 780
Query: 462 -AKELLKPEA-----DPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPE 507
A LK A P P E AP GP + + K P PT P+
Sbjct: 781 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 832
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 76.3 bits (186), Expect = 4e-13
Identities = 121/506 (23%), Positives = 164/506 (32%), Gaps = 99/506 (19%)
Query: 2313 EGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGS 2372
+G+ GGT G P A RGR S T EG+ +E+P + +
Sbjct: 1064 DGRGGGTGGPNHPPAP---RGRTASE--------TRSEGSEYEEIPKRRRQRGSETGSET 1112
Query: 2373 KKSPPEPVDKRAKAPKA--------RPAPP--QPSPAPPAFTSC---------------- 2406
+S P DK A PK P PP PSPAP FT+
Sbjct: 1113 HESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGR 1172
Query: 2407 ----PAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRP-------- 2454
P P+ PA SLAP P T P P +E GP P
Sbjct: 1173 GGGRPPPQVCPGWSPPAKSLAPKK----PPTGPLPPSKEPLKEKLIPGPLSPVARGGSNG 1228
Query: 2455 ----GEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGS 2510
G E + G + K + L +E A E K L+L PA+
Sbjct: 1229 GSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTL----PAS-- 1282
Query: 2511 SEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSS 2570
AP P+ + P P KSPD + D A E ++S SS +S
Sbjct: 1283 ----APGPEEALTTVTVAPAPR-----RAAAKSPDLSNQNSDQANEEWETASESSDFTSE 1333
Query: 2571 SSSSSSSGSET--EGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSS 2628
+ + G G GG G +A SR + S S SS
Sbjct: 1334 RRGDKEAPPPVLLTPKAVGTPGGGGGGAVPG---ISAMSRGDLSQRAKDLSKRSFSSQRP 1390
Query: 2629 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDE--AA 2686
+ + SS SSS + S + ++ S ++
Sbjct: 1391 GMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGL 1450
Query: 2687 PAPTAGPSAQA-----------------ALPTKATKQAGKARPSAHSPGKKTPAPQ-PQA 2728
P P PS+ A AL +++Q P H P K PQ PQ
Sbjct: 1451 PLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGH-PRHKPGLPQAPQG 1509
Query: 2729 PPPQPTQPLQP-KAQAGAKSRPKKRE 2753
P P+P +P + +G S P E
Sbjct: 1510 PSPRPPTRYEPQRVNSGLSSDPHFEE 1535
Score = 59.3 bits (142), Expect = 5e-08
Identities = 192/886 (21%), Positives = 282/886 (31%), Gaps = 116/886 (13%)
Query: 1932 PKKGLGEPGPSLAAPTP-----GARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGP 1986
P+ G P P P P G GP PD+ GP P P
Sbjct: 399 PETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRG--------------GP--PCKPPAP 442
Query: 1987 EASDDDLWTRRR---SERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKD 2043
E +D+ W +RR S I L A + R A L + A D
Sbjct: 443 E-DEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPD 501
Query: 2044 RKDPRKKKKGKEAGPGAGLPPPRAPA-LPSEARAPHASSLTAAKRSKAKAKGKEVKKENR 2102
++ + + A P PPP P LP+ P AS+ T + A+ +
Sbjct: 502 KR-LKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPT 560
Query: 2103 GKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVERPL-TPAPRSCIIDKDELK- 2160
A L+ + + + LP E P P P + + K E K
Sbjct: 561 PGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKG 620
Query: 2161 DGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGE-RGNRPHIYCLEQLLQEAIIDVRPA 2219
DG+ + L Q P R E + + H + Q V P+
Sbjct: 621 DGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPS 680
Query: 2220 STRFLPQGTRIAAYWSQQY-----RCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPL 2274
PQ + A + Q + LYPG + R + + FD P
Sbjct: 681 P----PQPVTLGAVPAPQAPPPPPKALYPGALGR-------PPPMPPMNFDPRWMMIPPY 729
Query: 2275 SHIRLLPPDYKIQCAEPS--PALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGR 2332
RLL + P P+ LVP E D G + SE A
Sbjct: 730 VDPRLLQGRPPLDFYPPGVHPSGLVPR-------------ERSDSGGSSSEPFDRHAPAM 776
Query: 2333 GRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPA 2392
R+ + A + D +TP P ++P + + + R++ P P
Sbjct: 777 LRERGTPPVDPKLAWVG-----DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPP 831
Query: 2393 PPQPSPAP---------PAFTSCPAPEPFAE-LPAPATSLAPAPLITMPATRPKPKKARA 2442
PP + P P + P EP LP P S A + T P + +P K
Sbjct: 832 PPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQT-PPPKKEPPKEET 890
Query: 2443 AEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLG 2502
A+ +G + R+P V +G P+ + E R P G + G
Sbjct: 891 AQLTGPEAGRKPARG----VGSGGQGPPPPRRESRTET---RWGPRPGSSRRGIPPEEPG 943
Query: 2503 SYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDK---AQAEQDGAEESES 2559
+ P AG + P K + P P +++ P PD + + G +E+
Sbjct: 944 APPRRAGPIKKPPPPTKVEE----LPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPP 999
Query: 2560 SSSSSSGSSSSSSSSSSSGSET----EGEEEGDKNGDGGCGT-GGRNCSAASSRAASPAS 2614
+ + S S T G E G G GT GGR A S S
Sbjct: 1000 NGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYRE 1059
Query: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD 2674
+ + + ++S + S S S + S +
Sbjct: 1060 FRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSET------- 1112
Query: 2675 EDSSCSSDDEAAPAPTAGPSAQAAL---PTKATKQAGKARPSAHSPGKKTPAPQPQ---- 2727
+S + D+ AP P G Q L P A AR +A TP P
Sbjct: 1113 HESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGR 1172
Query: 2728 ---APPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLP 2770
PPPQ P A++ A PKK LP +KE K + +P
Sbjct: 1173 GGGRPPPQVCPGWSPPAKSLA---PKKPPTGPLPPSKEPLKEKLIP 1215
Score = 59.3 bits (142), Expect = 5e-08
Identities = 238/1037 (22%), Positives = 340/1037 (32%), Gaps = 221/1037 (21%)
Query: 147 GQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPA 206
G+PS+ GP + A AP + +P ++ S S D +
Sbjct: 1273 GKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTS 1332
Query: 207 KERAGRGGEPPPLFGKKDPRARGEEASGPRGVV---------DLTQEA-----RAEGRQD 252
+ R + PP L P+A G G G V DL+Q A R+ Q
Sbjct: 1333 ERRGDKEAPPPVLL---TPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQR 1389
Query: 253 RGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQD 312
G R R P G AG G + G GG R D
Sbjct: 1390 PGMERQNRRPGP--------------------GGKAGSSGSSSGGGGGGPGGRTGPGRGD 1429
Query: 313 EGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPA---------ATPAGVYTVFRE- 362
+ + + + P RP PLPPP PP+ A + PAG+ +
Sbjct: 1430 KRSWPSPKNRSRPPEERPPGLPLPPP------PPSSSAVFRLDQVIHSNPAGIQQALAQL 1483
Query: 363 QGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPG-SPRPLD 421
R+ V AP P +PG+ QAP G SPRP
Sbjct: 1484 SSRQGSVTAPGGHP---------------------------RHKPGLPQAPQGPSPRPPT 1516
Query: 422 RPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRG 481
R E R + + P P VR +P A V P P +R R
Sbjct: 1517 RYEPQRVNSGLSSDPHFEEP--GPMVRGVGGTPRDSAGV----------SPFPPKRRERP 1564
Query: 482 PAGPAAQQAAKL-----FGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHHSRAE 536
P P Q L G +P GP+ + + + G A T H +R
Sbjct: 1565 PRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESR--DTGTEALT-------PHIWNR-- 1613
Query: 537 EEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFA 596
+ ++S+K+Y P S P++ A E S S + SG
Sbjct: 1614 -----LHTATSRKSY------RPSSMEPWMEPLSPFEDVA--GTEMSQSDSGVDLSGD-- 1658
Query: 597 RDAVAVRPGGCGKK-SPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQLKRDP 655
V G C ++ SP GGL P G+S A +P G P G +R P
Sbjct: 1659 ---SQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNA-VPCEGPP---GSEPPRRPP 1711
Query: 656 ERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSG-------GSGRLGP----GL 704
P +G + E PP I +++ D G S R GP G
Sbjct: 1712 PAP-------HDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGT 1764
Query: 705 VDQERSLSL---SNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLA 761
D++ L L ++K + R+ LL + + +SK L
Sbjct: 1765 SDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEP----QSKNLDSGH 1820
Query: 762 RLHPTSCAPNGLNPNLMV-TGGPALAGSGRWSADPAAHLATHPWLPRSGNASMWLAGHPY 820
+ S + L P + + GP+ + + D H + + P G S+ HPY
Sbjct: 1821 CVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRP--GTPSL----HPY 1874
Query: 821 GLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPP 880
P L G AP G +L + Q+ +L +P+ + + PP
Sbjct: 1875 RSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLY---------PPP 1925
Query: 881 LWPALYPPG--RSPLHHAQQLQLFSQQHFLRQQEFLYLQ-QQAAQALELQRSAQLVQERL 937
+ LY P SPL LQ+ +Q +F Q Q+ L A Q L
Sbjct: 1926 SF--LYSPAFCPSPLPDTSLLQV--RQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLL 1981
Query: 938 KAQEHRAEMEEKGS--KRGLEAAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPS 995
+ + + GS A L GP L +PP LA P V P P+
Sbjct: 1982 PMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPAL---QPPSLAVRPPPAPATRVLPSPA 2038
Query: 996 PRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPT----PGITRKEEA 1051
R P + +A +L V P Y SS+ P + PPT G+ + +A
Sbjct: 2039 -RPFPASLGRA----ELHPVELKPFQDYQKL-SSNLGGPGSSRTPPTGRSFSGLNSRLKA 2092
Query: 1052 PENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLA 1111
PS + +F QA PP R P + T
Sbjct: 2093 ---------------TPSTYSGVFRTQRVDLYQQASPPDALRWIPKPWERTG-------- 2129
Query: 1112 PDVPLPADGPERLALSP 1128
P P +GP R A P
Sbjct: 2130 ---PPPREGPSRRAEEP 2143
Score = 53.9 bits (128), Expect = 2e-06
Identities = 72/285 (25%), Positives = 102/285 (35%), Gaps = 49/285 (17%)
Query: 2310 DTGEGKDGGTAGSE--EPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPS 2367
D +G+D G+E A G R P A K +GN + P TP
Sbjct: 343 DEEDGRDSDEEGAEGHRDSQSASGEERPPEADGK--------KGNSPNSEPPTP------ 388
Query: 2368 STPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPA-----PEPFAELPAPATSL 2422
T ++ S P P+ P PP P P P PA P + + P
Sbjct: 389 KTAWAETSRP---------PETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCK- 438
Query: 2423 APAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEAL- 2481
PAP A R + K++ + + RR EE E ++ + + K K+ E
Sbjct: 439 PPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFG 498
Query: 2482 ----LLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFED 2537
L+ +P A P + S + PPA P P P A P P E+
Sbjct: 499 APDKRLKAEPAA-----PPAAPSTPAPPPAVPKELPAPPAPPP-----ASAPTPETEPEE 548
Query: 2538 SGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETE 2582
P AQ+ + + S GS+SS+SS S S E
Sbjct: 549 ---PAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE 590
Score = 50.4 bits (119), Expect = 3e-05
Identities = 111/543 (20%), Positives = 172/543 (31%), Gaps = 82/543 (15%)
Query: 2289 AEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATL 2348
A P LVPS + + S G DGG A S R P+ +A GD+
Sbjct: 127 AAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSL---LSRFSREEFPTLQAAGDQDKAA 183
Query: 2349 EEGNPTDEVPSTPLALEPSST----------------PGSK-------------KSPPEP 2379
+E ++ +L P ++ P SK PP+
Sbjct: 184 KERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQF 243
Query: 2380 VDKRAKAPKAR-----PAPPQPSPAPPAFTSCP-APEPFAELPAPATSLAPAPLITMPAT 2433
R P P PP P P P P F + P S P L+ P
Sbjct: 244 PPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVE-PVG 302
Query: 2434 RPKP------KKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDP 2487
RP K+ ++ G EE + KL + + A R+
Sbjct: 303 RPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQ 362
Query: 2488 GAGGWQEP------------------KSLLSLGSYPPAA--GSSEPKAPWPKATDGDLAQ 2527
A G + P K+ + S PP G PK P P G A
Sbjct: 363 SASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGP-AG 421
Query: 2528 EPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEG 2587
GP + D G P A ++D A SSS S + + E +E
Sbjct: 422 NWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEE 481
Query: 2588 D--------KNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSS------SSSSSSSSSS 2633
K D G + A AA PA+ S+ + + + + +S+
Sbjct: 482 RRAACAEKLKRLDEKFGAPDKRLKA--EPAAPPAAPSTPAPPPAVPKELPAPPAPPPASA 539
Query: 2634 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGP 2693
+ + + + + S+ + +++ + S S+S+T S +S E GP
Sbjct: 540 PTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGP 599
Query: 2694 SAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKRE 2753
+P T K P G P P+ + L P+ Q + + K++
Sbjct: 600 EPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQ 659
Query: 2754 GVH 2756
H
Sbjct: 660 QQH 662
Score = 49.3 bits (116), Expect = 6e-05
Identities = 99/408 (24%), Positives = 140/408 (34%), Gaps = 61/408 (14%)
Query: 134 EPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHAPSARTPGGGHSSG 193
E P+ +P + P + Q P P A +L S S + G
Sbjct: 527 ELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEA 586
Query: 194 APAKGS-SSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGR-- 250
+P + S++GP PP+ K +P+ G GP T++ ++G
Sbjct: 587 SPVEPQLPSKEGPEPPEEVPPPTTPPV-PKVEPKGDG---IGP------TRQPPSQGLGY 636
Query: 251 ---QDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKE 307
Q PPR + L + + ++ Q G A +P + GA
Sbjct: 637 PKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQ-----QGSAPPTPVPPSPPQPVTLGAVP 691
Query: 308 AARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTVFREQGREH 367
A + + L PG P P+PP P+ PP P + QGR
Sbjct: 692 APQAPPPP-----PKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLL------QGRPP 740
Query: 368 RVVAPTFV-PSVEAFDERPGPIQIASQA--RDARAREREAGRP----------GVLQAPP 414
P V PS ER +S+ R A A RE G P V A P
Sbjct: 741 LDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATP 800
Query: 415 GSPRPLDRP--EGLREKNSVIRSLKRPPPADAPTVRATRASPDPRA-YVPAKELLKPEAD 471
PRPL P + E + +RS P P P + + P+ A P E
Sbjct: 801 AEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPG 860
Query: 472 PRPCERAPRGPAGPAAQQAAKLFGLEPGRPPP-------TGPEHKWKP 512
PRP P P + + AK+ P + PP TGPE KP
Sbjct: 861 PRPL------PWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKP 902
Score = 44.3 bits (103), Expect = 0.002
Identities = 63/275 (22%), Positives = 90/275 (32%), Gaps = 44/275 (16%)
Query: 923 ALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGP 982
A+E R + +ER +E RA EK + + A P P P A P
Sbjct: 463 AVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPP 522
Query: 983 AGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYA-YPATPSSHPTSPPPASPPP 1041
A K + PP+P PPA A P T P PPA P
Sbjct: 523 A--VPKELPAPPAP---------------------PPASAPTPETEPEEPAQAPPAQSTP 559
Query: 1042 TPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQP 1101
TPG+ SP + P + +PP P P
Sbjct: 560 TPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPV-----P 614
Query: 1102 TAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAE 1161
DG+ P P+ G L K + P + ++E L +++ + +
Sbjct: 615 KVEPKGDGIGPTRQPPSQG---LGYPKYQKSL--------PPRFQRQQQEQLLKQQQQHQ 663
Query: 1162 VEDMDEG---PTELPPL-ESPLPLPAAEAMATPSP 1192
+ +G PT +PP P+ L A A P P
Sbjct: 664 WQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPP 698
Score = 43.5 bits (101), Expect = 0.003
Identities = 101/426 (23%), Positives = 141/426 (33%), Gaps = 43/426 (10%)
Query: 178 SHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKD----PRARGEEAS 233
S A +A+ P S PA + + + P + A P G K G
Sbjct: 98 SDASTAQPP---ESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGD 154
Query: 234 GPRGVVDLTQEARAE-------GRQDRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNG 286
G R L++ +R E G QD+ ER S + + Q S G
Sbjct: 155 GGRASSLLSRFSREEFPTLQAAGDQDKAAK---ERESAEQSSGPGPSLRPQNSTTWRDGG 211
Query: 287 GAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLP-PPPAPPKGP 345
G G L ++ G Q G ++P P P LP PPP P+GP
Sbjct: 212 GRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMP-PFMYPPYLPFPPPYGPQGP 270
Query: 346 ---PAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDARARER 402
P P + R G R+V P PS+ D Q+ + D A
Sbjct: 271 YRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAH 330
Query: 403 E----AGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRA 458
E + G + EG R+ S +RPP AD + + P
Sbjct: 331 EEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGE-ERPPEADGKKGNSPNSEPPTPK 389
Query: 459 YVPAKELLKPEADPRPCERAP------RGPA---GPAAQQAAKLFGLEPGRPP-PTGPEH 508
A+ PE +P P P RGPA GP + G P +PP P +
Sbjct: 390 TAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDR--GGPPCKPPAPEDEDE 447
Query: 509 KWKPFELGNFAATQMAVLAA----QHHHSRAEEEAAVVAASSSKKAYLDPGAVLPRSAAT 564
W+ + + +AV A + R +EE A K+ GA R A
Sbjct: 448 AWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAE 507
Query: 565 CGRPVA 570
P A
Sbjct: 508 PAAPPA 513
Score = 42.7 bits (99), Expect = 0.005
Identities = 227/994 (22%), Positives = 314/994 (31%), Gaps = 162/994 (16%)
Query: 245 ARAEGRQDRGPPRLAERLSP--FLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGR 302
A G Q G +A R+ P L K +N P+V +LV + G
Sbjct: 39 APRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNV--------------SLVPKDGT 84
Query: 303 GGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAAT---PAGVYTV 359
G A + + D + + P +P P+ P PK PPA P T P+GV +
Sbjct: 85 GWASKQEQSDPKSSDASTAQP--PESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKS- 141
Query: 360 FREQGREHRVVAPTFVPS--VEAFDERPGPIQIASQARDARAREREAGR----PGVLQAP 413
+ + H S + F P A+ +D A+ERE+ PG P
Sbjct: 142 WAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRP 201
Query: 414 PGSPRPLD----RPEGLREKNSVIRSLKRP----PPADAPTVRATRASPDPRAYVPAKEL 465
S D P+ L +S + P P+ P R P Y P
Sbjct: 202 QNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLP- 260
Query: 466 LKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAV 525
P P+ R P P GP+ + ++ G PP E +P L +
Sbjct: 261 FPPPYGPQGPYRYPT-PDGPS--RFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQ 317
Query: 526 LAAQHHHSRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAM 585
L ++ A V K + + G A R D SA SGE
Sbjct: 318 LDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHR---DSQSA---SGEERP- 370
Query: 586 QSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAA 645
P GKK G P P +A A ++ G PA
Sbjct: 371 ------------------PEADGKK----GNSPNSEPPTPKTAWAETSRPPETEPGPPA- 407
Query: 646 GGGRQLKRDPERPESAKAFGREGS-GAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGL 704
P+ P G G+ G G+ R P A + ++ R
Sbjct: 408 ---------PKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRR----- 453
Query: 705 VDQERSLSLSNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLR-ESKELADLARL 763
+SL+ + R +E+ E R+ R EKL R + K A RL
Sbjct: 454 KQSSSEISLAVERARRRREEE---------ERRMQEERRAACAEKLKRLDEKFGAPDKRL 504
Query: 764 HPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATHPWLPRSGNASMWLAGHPYGLG 823
AP P T P A A PA A+ P A P
Sbjct: 505 KAEPAAP----PAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEP---AQAPPAQS 557
Query: 824 PPSLHQGMAPAFPPGLGG-SLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPP-- 880
P+ AP G G S S+ F P QL PS P E + T PP
Sbjct: 558 TPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQL---PSKEGPEPPEEVPPPTTPPVP 614
Query: 881 --------LWPALYPPGRSPLHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQL 932
+ P PP + + Q L F RQQ+ L+QQ
Sbjct: 615 KVEPKGDGIGPTRQPPSQGLGYPKYQKSL--PPRFQRQQQEQLLKQQ------------- 659
Query: 933 VQERLKAQEHRAEMEEKGSKRGLEA-AGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVS 991
Q+H+ + ++GS T G P+ PP P Y A+
Sbjct: 660 -------QQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPP---PPPKALYPGALG 709
Query: 992 -PPPSP--RASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRK 1048
PPP P P + + +PP YP P HP+ P + G + +
Sbjct: 710 RPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYP--PGVHPSGLVPRERSDSGGSSSE 767
Query: 1049 ---EEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAA 1105
AP + E+ ++ P A D+ F A P RP L+ A
Sbjct: 768 PFDRHAPAMLRERGTPPVD-----PKLAWVGDV-----FTATPAE-PRPLTSPLRQAADE 816
Query: 1106 DADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDM 1165
D G+ + P P LA P I+ E P PL EV +
Sbjct: 817 DDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKI 876
Query: 1166 DEGPTEL-PPLESPLPLPAAEAMATPSPAGGCGG 1198
P + PP E L EA P+ G GG
Sbjct: 877 QTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGG 910
Score = 41.2 bits (95), Expect = 0.015
Identities = 39/164 (23%), Positives = 61/164 (37%), Gaps = 26/164 (15%)
Query: 2658 SSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTA--GPSAQAALPTKATKQAGKARPSAH 2715
S S + DS +S +E P G S + PT T A +RP
Sbjct: 342 SDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPET 401
Query: 2716 SPGKKTPAPQPQAPPPQ-------------------PTQPLQPKAQAGAKSRPKKREGVH 2756
PG PAP+P PPP P +P P+ + A + +K+
Sbjct: 402 EPG--PPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSE 459
Query: 2757 LPTTKELAKRQRLPS---VENRPKIAAFLPARQLWKWFGKPTQR 2797
+ E A+R+R ++ + A ++L + FG P +R
Sbjct: 460 ISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKR 503
Score = 40.0 bits (92), Expect = 0.034
Identities = 56/232 (24%), Positives = 84/232 (36%), Gaps = 42/232 (18%)
Query: 1837 EEEDEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKA 1896
E E+ A G + A +PG EE A + P+P + S L +
Sbjct: 1263 ERENAARGSEGKPSLTLPASAPGPEE------ALTTVTVAPAPRRAAAKSP-DLSNQNSD 1315
Query: 1897 RKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPS 1956
+ EE + T E +D SE + K +P +L K +G PG PG S
Sbjct: 1316 QANEEWE----TASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGI-----S 1366
Query: 1957 SPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVS 2016
+ + L+ +++ + PG E R++ R P P
Sbjct: 1367 AMSRGDLSQRAKDLSKRSFSSQRPGME-------------RQNRR----------PGPGG 1403
Query: 2017 TAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGK---EAGPGAGLPPP 2065
A ++ +S GG R GR R P K + + E PG LPPP
Sbjct: 1404 KAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPP 1455
Score = 36.6 bits (83), Expect = 0.38
Identities = 25/109 (22%), Positives = 47/109 (43%), Gaps = 10/109 (9%)
Query: 405 GRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKE 464
G+ +Q P +PR GL+ V + + PPPA+ P+++A DP + K+
Sbjct: 28 GKSLEIQKPAVAPR-----HGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKD 82
Query: 465 -----LLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEH 508
+ ++DP+ + + P A++ + PP PE+
Sbjct: 83 GTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPEN 131
Score = 36.6 bits (83), Expect = 0.38
Identities = 43/154 (27%), Positives = 56/154 (36%), Gaps = 32/154 (20%)
Query: 14 GPPPP--LLSGLAM-----DSHRVGAATAGRLPASGLPGPLPPGKYMAGLNLHPHPGEAF 66
GP PP LLSGLA+ D + A G+LPA G+ P P Y P P +
Sbjct: 1884 GPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSL 1943
Query: 67 L---------GSFVASGMGPSASSHGSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFS 117
L F ++ + P S P P+ S LP+V F
Sbjct: 1944 LQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVV---------NFG 1994
Query: 118 HLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSI 151
LP P+ PP S P+ L PS+
Sbjct: 1995 SLPPAPPPA-------PPPLSLLPVGPALQPPSL 2021
Score = 35.4 bits (80), Expect = 0.85
Identities = 28/91 (30%), Positives = 35/91 (38%), Gaps = 7/91 (7%)
Query: 2366 PSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPA 2425
PS P + P VD + PP P PAPP + P L P+ ++ P
Sbjct: 1971 PSGAPAQQMLLPM-VDSQLPVVNFGSLPPAPPPAPPPLSLLPVG---PALQPPSLAVRPP 2026
Query: 2426 PLITMPATRPKPKKARAAEESGAKGPRRPGE 2456
P PATR P AR S + P E
Sbjct: 2027 P---APATRVLPSPARPFPASLGRAELHPVE 2054
Score = 34.3 bits (77), Expect = 1.9
Identities = 49/190 (25%), Positives = 65/190 (34%), Gaps = 27/190 (14%)
Query: 971 LPRKPPGLAAGPAGTYGKAVSPP--------PSPRASPVAALKAKVIQKLEDVSKPPAYA 1022
+P PP LA+ P A PP P PR P +V + + PP
Sbjct: 828 VPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAK----IQTPPPKK 883
Query: 1023 YPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRY 1082
P + + P A P G+ + P + E + P P + IPP
Sbjct: 884 EPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTET-RWGPRPGSSR-RGIPPEE 941
Query: 1083 PFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITE 1142
P PP P PT + P PL G E KP + P KIT+
Sbjct: 942 P--GAPPRRAGPIKKPPPPTKVEEL----PPKPLE-QGDET------PKPPKPDPLKITK 988
Query: 1143 PLREGPEEEP 1152
GP+E P
Sbjct: 989 GKLGGPKETP 998
Score = 34.3 bits (77), Expect = 1.9
Identities = 165/756 (21%), Positives = 233/756 (30%), Gaps = 176/756 (23%)
Query: 324 LLPGPRPCPSP----LPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVE 379
L P + P+P L P P P APP+ PA R R RV P VPS
Sbjct: 1117 LAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPA------RFTARGGRVFTPRGVPS-- 1168
Query: 380 AFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSL--K 437
R R GRP P SP +SL K
Sbjct: 1169 -------------------RRGRGGGRPPPQVCPGWSP--------------PAKSLAPK 1195
Query: 438 RPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLE 497
+PP P P+KE LK + P P RG + + G+E
Sbjct: 1196 KPPTGPLP---------------PSKEPLKEKLIPGPLSPVARGGSNGGSN-----VGME 1235
Query: 498 PGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAV 557
G P Q + + E E A + L A
Sbjct: 1236 DGERP-----------RRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAP 1284
Query: 558 LPRSAATCGRPVADMHSAAHGSGEASAMQSLIK----YSGSFARDAVAVRPGGCGKKSPF 613
P A T AA S + S S + S + D + R G K++P
Sbjct: 1285 GPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRG--DKEAPP 1342
Query: 614 GGLGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQG 673
L T K P G S G + + L S ++F + G
Sbjct: 1343 PVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDL--------SKRSFSSQRPGM-- 1392
Query: 674 EAEVRHPPVGIAVAVARQKDSGG----SGRLGPGLVDQERSLSLSNVKGHGRADEDCVDD 729
E + R P G + GG GR GPG D+ S N
Sbjct: 1393 ERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKN-------------- 1438
Query: 730 RARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSG 789
R+R EER G L S + L ++ ++ P G+ L A S
Sbjct: 1439 RSRPPEERPPGLPLPPPPP----SSSAVFRLDQVIHSN--PAGIQQAL------AQLSSR 1486
Query: 790 RWSAD-PAAHLATHPWLPRSGNASMWLAGHPYGLGPPSLHQGMA--PAFPP------GLG 840
+ S P H P LP++ P P ++ G++ P F G+G
Sbjct: 1487 QGSVTAPGGHPRHKPGLPQAPQGPS--PRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVG 1544
Query: 841 GSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALY----PPGRSPLHHA 896
G+ + P + + P EL++ ++PP + + P G P +
Sbjct: 1545 GTPRDSAGVSPFPPKRR------ERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAES 1598
Query: 897 QQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLE 956
+ + L + L ++ S + E L E A E S G++
Sbjct: 1599 RD----TGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVD 1654
Query: 957 AAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVS 1016
+G + + ++GP P G G G A PP P S
Sbjct: 1655 LSGDSQV-SSGPCSQRSSPDG------GLKGAAEGPPKRPGGS----------------- 1690
Query: 1017 KPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAP 1052
P A P P S PP PPP P ++E P
Sbjct: 1691 -SPLNAVPC--EGPPGSEPPRRPPPAPHDGDRKELP 1723
Score = 33.1 bits (74), Expect = 4.2
Identities = 72/292 (24%), Positives = 103/292 (35%), Gaps = 71/292 (24%)
Query: 1891 EAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGA 1950
E ++ +++ +R S G+E +D K +P PK+G P LA P PGA
Sbjct: 1093 EYEEIPKRRRQRGSETGSETHESDLAPS---DKEAPT----PKEGTLTQVP-LAPPPPGA 1144
Query: 1951 RGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAG-PEASDDDLWTRRRSERIFLHDASA 2009
P SP A+ GR P G G P W+ A +
Sbjct: 1145 ----PPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSP---------PAKS 1191
Query: 2010 AAPAPVSTAPATKTSRCAKG----GPLSP---------------------RKDAGRAKDR 2044
AP T P + K GPLSP R+ GRA+ +
Sbjct: 1192 LAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQ 1251
Query: 2045 KDPRKKKKGKEAGPGAGLPPPRAPA--LPSEARAPHASSLT---AAKRSKAKAKGKEVKK 2099
P + ++ K+ A P+ LP+ A P + T A +A AK ++
Sbjct: 1252 DKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSN 1311
Query: 2100 ENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVERP----LTP 2147
+N S A E++E +SS E R G E P LTP
Sbjct: 1312 QN------------SDQANEEWETASESSDFTSE---RRGDKEAPPPVLLTP 1348
Score = 32.0 bits (71), Expect = 9.4
Identities = 55/257 (21%), Positives = 87/257 (33%), Gaps = 20/257 (7%)
Query: 938 KAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPR 997
+++E R+ E +G G+ G T GP P P G A + G P R
Sbjct: 1050 RSREFRSYREFRGDD------GRGG-GTGGPNH-PPAPRGRTASETRSEGSEYEEIPKRR 1101
Query: 998 ASPVAALKAKVIQK-LEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVV 1056
+ ++ + L K T + P +PPP PP+P R V
Sbjct: 1102 RQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVF 1161
Query: 1057 EKKDLELEK---EAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADG-LAP 1112
+ + + P Q PP P G P P +P G L+P
Sbjct: 1162 TPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTG-PLPPSKEPLKEKLIPGPLSP 1220
Query: 1113 DVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPTEL 1172
++G + + ++P R + + +++P R +K E E+ G
Sbjct: 1221 VARGGSNGGSNVGMEDGERPRRRRHGRAQQ------QDKPPRFRRLKQERENAARGSEGK 1274
Query: 1173 PPLESPLPLPAAEAMAT 1189
P L P P E T
Sbjct: 1275 PSLTLPASAPGPEEALT 1291
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 76.3 bits (186), Expect = 4e-13
Identities = 60/146 (41%), Positives = 74/146 (50%), Gaps = 13/146 (8%)
Query: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665
+S +++ AS+SS SSS SSS S S SS S S SSS SS SS SS SS S S S S S S
Sbjct: 544 TSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFS 603
Query: 2666 SSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQ 2725
SS S S T S + PAP G + + K K P P A +
Sbjct: 604 SSPSPSPTPSPHRPSIRTKGEPAPPPGKAGE--------KSVKKPAP----PPAPPQATK 651
Query: 2726 PQAPPPQPTQPLQPKAQAGAKSRPKK 2751
AP P+PT+P P+ +A K RP +
Sbjct: 652 TTAPVPEPTKPGDPR-EARRKERPAR 676
Score = 68.6 bits (166), Expect = 9e-11
Identities = 87/346 (25%), Positives = 132/346 (38%), Gaps = 50/346 (14%)
Query: 2434 RPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTS-PKSKKAKEALLLREDPGAGGW 2492
R + ++ +E G PR P + E T+ P+ K+A E +DP
Sbjct: 468 RDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEW----KDPWRRS- 522
Query: 2493 QEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQD 2552
+ PK L + S P+ K A+ + ++ ++ SG+ +S ++ +
Sbjct: 523 KSPKKKLGV-SVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSS 581
Query: 2553 -GAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGD--KNGDGGCGTGGRNCSAASSRA 2609
+ S SS S S S S S SSS S S T G+ G + A
Sbjct: 582 YSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPA 641
Query: 2610 ASPASSSSSSSSSSSSSSSS-----------------------SSSSSSSSSSSSSSSSS 2646
PA ++ +++ + S S S S SS S SSS
Sbjct: 642 PPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSR 701
Query: 2647 SSSSSSSSSSSSSSSSSSSSSSSSSTTDE-----DSSCSSDDEAAPAPTA---------- 2691
S S S SS SS SS++SSSSS+ S +++ S SS +PAP
Sbjct: 702 SRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKK 761
Query: 2692 --GPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQ 2735
G + +T+ A+P A + P+ QAPP QP Q
Sbjct: 762 EDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQ 807
Score = 57.4 bits (137), Expect = 2e-07
Identities = 93/450 (20%), Positives = 143/450 (31%), Gaps = 60/450 (13%)
Query: 2298 PSAKRRSRKTSKDTGEGKDGGTAGSEEPG----AKARGRGRKPSAKAKGDRAATLEE-GN 2352
PS RR RKTS + + + S +R R R S + R++
Sbjct: 535 PSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSG 594
Query: 2353 PTDEVPSTPLALEPSSTPG-------SKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTS 2405
S + PS TP +K P P K + +PAPP PAPP T
Sbjct: 595 SRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPP---PAPPQATK 651
Query: 2406 CPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLD 2465
AP P P P++AR E PRR L
Sbjct: 652 TTAPVP------------------EPTKPGDPREARRKERPARTPPRRR--------TLS 685
Query: 2466 HEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDL 2525
G S S + S S S + S + A
Sbjct: 686 GSGSGSGSSYSGSSS--RSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSAS 743
Query: 2526 AQEPGPGLTFEDSGNPKSPDKAQAE---QDGAEESESSSSSSSGSSSSSSSSSSSGSETE 2582
++ P P T ++ G K D + E +D + + S+ +G SS S+ +
Sbjct: 744 SRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPG 803
Query: 2583 GEEEGD-----------KNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSS 2631
++G N G+ R + R + P + ++S S S
Sbjct: 804 QPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSG 863
Query: 2632 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSS--CSSDDEAAPAP 2689
S +S + ++ + S S SSS ++ +S ++ ++ A
Sbjct: 864 GRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKAS 923
Query: 2690 TAGPSAQAALPTKATKQAGKARPSAHSPGK 2719
T + KA + A AR A PGK
Sbjct: 924 TLSRREELLKQLKAVEDA-IARKRAKIPGK 952
Score = 55.1 bits (131), Expect = 1e-06
Identities = 136/647 (21%), Positives = 218/647 (33%), Gaps = 101/647 (15%)
Query: 1482 DFRMRLAEVQ--RQYKEKQRELVKLQRRRDSEDRREEPHRSLARRGPGRPRKRTHAPSAL 1539
+FR++ E + Y+E++RE + R+R+ E R E R RR R R+R H
Sbjct: 387 NFRVQYTETEPYHNYRERERERERENRQRERE-RERERDRERERRQREREREREH----- 440
Query: 1540 SPPRKRGKSGHSSGKLSSKSLLTSDDYELGAGIRKRHKGSEEEHDALIGMGKARGRNQTW 1599
+R K + + D+ + R R K E+E GK + R+
Sbjct: 441 ----ERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKE------KGKPKPRSPQP 490
Query: 1600 DEHEASSDFISQLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTS 1659
+A KK+ A+ Q + + D+ K P++ S S K S
Sbjct: 491 PSRQAEP--------PKKEAATTGPQ----------VKRADEWKDPWRRSKSPKKKLGVS 532
Query: 1660 GGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAH 1719
R K + A S SSR + + +R ++R S++
Sbjct: 533 VSPSR-----ARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRS-----RSRSSSYSSY 582
Query: 1720 SPFASEVSSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTK 1779
S +S SS+S + P+ P+ S PS+ G K K
Sbjct: 583 SSRSSRHSSFSGSRSRSRS----FSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVK 638
Query: 1780 RGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEE 1839
+ P P AT P + + R E+ ++ + L
Sbjct: 639 KPAPPP---APPQATKTTAPVPEPTKPGDPR--------EARRKERPARTPPRRRTLSGS 687
Query: 1840 DEASGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAK-QKARK 1898
SG Y G+ R+ S L S + ++ +S+ + +V L + A
Sbjct: 688 GSGSGSSYS-GSSSRSRS--LSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASS 744
Query: 1899 KEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEP--GPSLAAPTPGARGPDPS 1956
+ + E + E VK KR +P K P G S P+ + P P
Sbjct: 745 RSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAP-PG 803
Query: 1957 SPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVS 2016
P + K K L + G E SD D R+S P +
Sbjct: 804 QPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKD----RQS-------------PPPA 846
Query: 2017 TAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARA 2076
P T R ++ RK GR K R++ + +A P APA +
Sbjct: 847 KRPNTSPDRGSR-----DRKSGGRLGSPKPERQRGQNSKA--------PAAPADRKRQLS 893
Query: 2077 PHASSLTAAKRSKAKAKGKEVKKENRGKGGAVSK---LMESMAAEED 2120
P + S + KA GK +S+ L++ + A ED
Sbjct: 894 PQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVED 940
Score = 41.2 bits (95), Expect = 0.015
Identities = 81/364 (22%), Positives = 116/364 (31%), Gaps = 62/364 (17%)
Query: 207 KERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLT--QEARAEG-----RQDRGPPR-L 258
KER G+P P + P+ +A P+ T Q RA+ R+ + P + L
Sbjct: 474 KEREKEKGKPKP----RSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKL 529
Query: 259 AERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDE----- 313
+SP A + K +A S + +G G ++ +R
Sbjct: 530 GVSVSPSRARRRRKTSASSASASNSSRSSSRSSSY------SGSGSSRSRSRSSSYSSYS 583
Query: 314 ----------GARLLRRTETLLPGPRPCPSPLPP------PPAPPKG--------PPAPP 349
G+R R+ + P P P PSP P PAPP G PAPP
Sbjct: 584 SRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPP 643
Query: 350 AATPAGVYTVF-----------REQGREHRVV-APTFVPSVEAFDERPGPIQIASQARDA 397
A P T RE R+ R P ++ G S +R
Sbjct: 644 PAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSR 703
Query: 398 RAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPR 457
+ S +D + + S + S PA A T + S
Sbjct: 704 SLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKED 763
Query: 458 AYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPP-TGPEHKWKPFELG 516
K P + P G G ++QQ + PG+P T HK L
Sbjct: 764 GVKEEKRKRDSSTQPPKSAKPPAG--GKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLL 821
Query: 517 NFAA 520
N AA
Sbjct: 822 NKAA 825
Score = 38.5 bits (88), Expect = 0.100
Identities = 61/312 (19%), Positives = 99/312 (31%), Gaps = 40/312 (12%)
Query: 1893 KQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLR----PKKGLGEPGPSLAAPT- 1947
+++A++ E+ + + E + + K + RSP R PKK GP +
Sbjct: 455 RERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADE 514
Query: 1948 ---PGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFL 2004
P R P ++ + R+ RK + +S ++ S R
Sbjct: 515 WKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRS 574
Query: 2005 HDAS------------------------AAAPAPVSTAPATKTSRCAKGGPLSPRKDAGR 2040
+S +++P+P T + S KG P P AG
Sbjct: 575 RSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGE 634
Query: 2041 AKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKE 2100
+K + A +P P P P EAR + T +R G
Sbjct: 635 KSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSS 694
Query: 2101 NRGKGGAVSKLMESMAAEEDFEPNQDSSF----SEDEHL----PRGGAVERPLTPAPRSC 2152
G L S + + SS SED + P A R PA
Sbjct: 695 YSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRK 754
Query: 2153 IIDKDELKDGLR 2164
K + +DG++
Sbjct: 755 EKGKSKKEDGVK 766
Score = 38.1 bits (87), Expect = 0.13
Identities = 39/184 (21%), Positives = 69/184 (37%), Gaps = 8/184 (4%)
Query: 1966 EKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSR 2025
E+ + K R ++ +E D+ R +R + P P S P ++ +
Sbjct: 437 EREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAE 496
Query: 2026 CAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAA 2085
K + RA + KDP ++ K + G + P RA R ASS +A+
Sbjct: 497 PPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRA----RRRRKTSASSASAS 552
Query: 2086 KRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVERPL 2145
S++ ++ G G + S+ S + ++ SSFS R +
Sbjct: 553 NSSRSSSRSSSYS----GSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSP 608
Query: 2146 TPAP 2149
+P P
Sbjct: 609 SPTP 612
Score = 33.5 bits (75), Expect = 3.2
Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 20/130 (15%)
Query: 2252 DLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDT 2311
DL D+ +T E D+ + L + +P EP+PA+ A++ + ++
Sbjct: 111 DLRDEASSVTRELDEHE-----LDYDEEVPE-------EPAPAVQEDEAEKAGAEDDEEK 158
Query: 2312 GEG--KDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSST 2369
GEG ++ G AG + G K K K K D +++G E+ L
Sbjct: 159 GEGTPREEGKAGVQSVGEKESLEAAK--EKKKEDDDGEIDDG----EIDDDDLEEGEVKD 212
Query: 2370 PGSKKSPPEP 2379
P +K P P
Sbjct: 213 PSDRKVRPRP 222
Score = 32.0 bits (71), Expect = 9.4
Identities = 68/281 (24%), Positives = 102/281 (36%), Gaps = 71/281 (25%)
Query: 463 KELLKPEADPRPCERAPRGP---AGPAAQQAAKLFGLEPGRPPPTGPEHK----WK-PFE 514
KE K + P+P R+P+ P A P ++AA TGP+ K WK P+
Sbjct: 474 KEREKEKGKPKP--RSPQPPSRQAEPPKKEAAT-----------TGPQVKRADEWKDPWR 520
Query: 515 LGNFAATQMAVLAAQHHHSRAEEEAAVVAA-------SSSKKAYLDPGAVLPRSAATCGR 567
++ V + R + +A A+ SS +Y G+ RS ++
Sbjct: 521 RSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYS 580
Query: 568 PVADM---HSAAHGSGEAS-AMQSLIKYSGSFARDAVAVR--------PGGCGKKSPFGG 615
+ HS+ GS S + S S + + ++R PG G+KS
Sbjct: 581 SYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKS---- 636
Query: 616 LGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEA 675
KP P P A++ A +P P G + R ERP R SG+
Sbjct: 637 --VKKPAPPPAPPQATKTTAPVPE---PTKPGDPREARRKERPARTPPRRRTLSGS---- 687
Query: 676 EVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLSLSNV 716
GSG G + RSLS+S+V
Sbjct: 688 ------------------GSGSGSSYSGSSSRSRSLSVSSV 710
>gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]
Length = 375
Score = 75.9 bits (185), Expect = 6e-13
Identities = 56/140 (40%), Positives = 72/140 (51%), Gaps = 9/140 (6%)
Query: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGSETEGE-EEGDKNGDGGC---GTGGRNCSAAS 2606
Q S S S SSG+SS+ S SS S T + + C GT +CS S
Sbjct: 193 QSSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQS 252
Query: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-----SSS 2661
SR +S S SS +SS+S S SS +SS+ S SS +SS+S S SS +SS+ S +
Sbjct: 253 SRTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSCQSSRTSSTCSCQFSRT 312
Query: 2662 SSSSSSSSSSTTDEDSSCSS 2681
SS+S S SS T SC S
Sbjct: 313 SSTSCSCQSSRTSSTCSCQS 332
Score = 74.3 bits (181), Expect = 2e-12
Identities = 54/178 (30%), Positives = 83/178 (46%), Gaps = 7/178 (3%)
Query: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDG----GCGTGGRNCSAAS 2606
Q S S S SS +SS+ S +S S T + + GT +C+ S
Sbjct: 124 QSSRTSSTSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQS 183
Query: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666
SR +S S SS +SS+S S SS +SS+ S SS +SS+S S SS +SS+ S SS +
Sbjct: 184 SRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGT 243
Query: 2667 SSSS---STTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
SS+S ++ S+CS + + + T + + +G + S +T
Sbjct: 244 SSTSCSWQSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSCQSSRT 301
Score = 72.8 bits (177), Expect = 5e-12
Identities = 52/128 (40%), Positives = 69/128 (53%), Gaps = 12/128 (9%)
Query: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616
S + S SSG+SS+S S SSG+ + + GT +CS SS +S S
Sbjct: 187 SSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSS-------GTSSTSCSCQSSGTSSTCSCQ 239
Query: 2617 SSSSSSSSSSSSSSSSSS-----SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
SS +SS+S S SS +SS SS +SS+S S SS +SS+ S SS +SS+S S SS
Sbjct: 240 SSGTSSTSCSWQSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSCQSS 299
Query: 2672 TTDEDSSC 2679
T SC
Sbjct: 300 RTSSTCSC 307
Score = 72.4 bits (176), Expect = 6e-12
Identities = 52/138 (37%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Query: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDG----GCGTGGRNCSAAS 2606
Q S S S SSG+SS+ S SS S T + + GT +CS S
Sbjct: 216 QSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSGTSSTSCSCQS 275
Query: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666
S +S S SS +SS+S S SS +SS+ S S +SS+S S SS +SS+ S SS +
Sbjct: 276 SGTSSTCSCQSSGTSSTSCSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCSCQSSGT 335
Query: 2667 SSSS----STTDEDSSCS 2680
SS+S S+ +SCS
Sbjct: 336 SSTSCICWSSGTSSTSCS 353
Score = 72.0 bits (175), Expect = 8e-12
Identities = 57/191 (29%), Positives = 86/191 (45%), Gaps = 24/191 (12%)
Query: 2546 KAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAA 2605
KA +Q A S S SS SS+ S SS + S + G T +C+
Sbjct: 5 KAACKQHRASSSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSG---------TSSTSCNWQ 55
Query: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---------------SSS 2650
SSR +S S SS +SS+S S SS +SS+ S SS +SS+S SS
Sbjct: 56 SSRTSSTCSCQSSGTSSTSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCCCQSSR 115
Query: 2651 SSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKA 2710
+SS+S S SS +SS+S S ++ S+CS + + + T + + +G +
Sbjct: 116 TSSTSCSCQSSRTSSTSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTS 175
Query: 2711 RPSAHSPGKKT 2721
S + +T
Sbjct: 176 STSCNWQSSRT 186
Score = 71.6 bits (174), Expect = 1e-11
Identities = 50/159 (31%), Positives = 78/159 (49%), Gaps = 3/159 (1%)
Query: 2558 ESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSS 2617
+SS +SS+ S SS +SS+ + T +CS SSR +S S S
Sbjct: 112 QSSRTSSTSCSCQSSRTSSTSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQS 171
Query: 2618 SSSSSSS---SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTD 2674
S +SS+S SS +SS+ S SS +SS+S S SS +SS+ S SS +SS+S S ++
Sbjct: 172 SGTSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSG 231
Query: 2675 EDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPS 2713
S+CS + + + T + + +G + S
Sbjct: 232 TSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSGTSSTS 270
Score = 70.1 bits (170), Expect = 3e-11
Identities = 49/125 (39%), Positives = 67/125 (53%), Gaps = 7/125 (5%)
Query: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616
S + S SSG+SS+S S SSG+ + + GT +CS SSR +S S
Sbjct: 256 SSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSS-------GTSSTSCSCQSSRTSSTCSCQ 308
Query: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDED 2676
S +SS+S S SS +SS+ S SS +SS+S SS +SS+S S S +SS+S
Sbjct: 309 FSRTSSTSCSCQSSRTSSTCSCQSSGTSSTSCICWSSGTSSTSCSGRFSGTSSTSCNCRS 368
Query: 2677 SSCSS 2681
S SS
Sbjct: 369 SGTSS 373
Score = 59.3 bits (142), Expect = 5e-08
Identities = 43/115 (37%), Positives = 58/115 (50%), Gaps = 6/115 (5%)
Query: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG-----TGGRNCSAA 2605
Q S S S SSG+SS+ S SS S T + + C T +CS
Sbjct: 262 QSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSCQSSRTSST-CSCQFSRTSSTSCSCQ 320
Query: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2660
SSR +S S SS +SS+S SS +SS+S S S +SS+S + SS +SS+S
Sbjct: 321 SSRTSSTCSCQSSGTSSTSCICWSSGTSSTSCSGRFSGTSSTSCNCRSSGTSSTS 375
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 150,102,331
Number of Sequences: 37866
Number of extensions: 9886099
Number of successful extensions: 228149
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1926
Number of HSP's successfully gapped in prelim test: 2620
Number of HSP's that attempted gapping in prelim test: 65531
Number of HSP's gapped (non-prelim): 84815
length of query: 2968
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2848
effective length of database: 13,703,598
effective search space: 39027847104
effective search space used: 39027847104
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.