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Search of human proteins with 16950625
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens]
(154 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens] 313 4e-86
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 313 4e-86
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 313 4e-86
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 313 4e-86
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 313 4e-86
gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens] 306 3e-84
gi|157785645 SPEG complex locus [Homo sapiens] 85 2e-17
gi|153792294 myopalladin [Homo sapiens] 82 2e-16
gi|110349721 titin isoform novex-3 [Homo sapiens] 79 1e-15
gi|110349719 titin isoform N2-A [Homo sapiens] 79 1e-15
gi|110349717 titin isoform novex-2 [Homo sapiens] 79 1e-15
gi|110349713 titin isoform novex-1 [Homo sapiens] 79 1e-15
gi|110349715 titin isoform N2-B [Homo sapiens] 79 1e-15
gi|93102361 palladin [Homo sapiens] 77 6e-15
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 71 3e-13
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 71 3e-13
gi|115511036 alpha-kinase 3 [Homo sapiens] 69 2e-12
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 66 1e-11
gi|156104903 myomesin 2 [Homo sapiens] 64 5e-11
gi|133908641 myosin binding protein C, fast type [Homo sapiens] 61 3e-10
gi|148839296 immunoglobulin-like and fibronectin type III domain... 59 1e-09
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 58 4e-09
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 58 4e-09
gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor [... 57 6e-09
gi|148596957 myosin binding protein C, cardiac [Homo sapiens] 57 8e-09
gi|209693444 myotilin isoform b [Homo sapiens] 57 8e-09
gi|5803106 myotilin isoform a [Homo sapiens] 57 8e-09
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 57 8e-09
gi|11321597 kinase insert domain receptor precursor [Homo sapiens] 55 2e-08
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 55 2e-08
>gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens]
Length = 154
Score = 313 bits (802), Expect = 4e-86
Identities = 154/154 (100%), Positives = 154/154 (100%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60
MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60
Query: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
Query: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 313 bits (802), Expect = 4e-86
Identities = 154/154 (100%), Positives = 154/154 (100%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60
MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1710 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1769
Query: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
Query: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1830 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
Score = 71.6 bits (174), Expect = 2e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I V +D KYTC+A N G T EL VE
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 68.6 bits (166), Expect = 2e-12
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 2/119 (1%)
Query: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
E + +L VA KP P F + + DL+V++GS ++ G P PEV+W +
Sbjct: 602 EKKSSRKSEYLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 145
I+ES F + SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 661 NEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718
Score = 62.0 bits (149), Expect = 2e-10
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 36 FLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 91
F E +P + P F+ + + V EG RF CKI G P P+V W K + ++
Sbjct: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
Query: 92 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 204 SARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 60.5 bits (145), Expect = 6e-10
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 567
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Score = 58.5 bits (140), Expect = 2e-09
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 18 TSPLNAEKLESEEDVSQAFLEAVAEE--KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 75
T P L S++ VS+A + E + P F + EV E +F C++ G
Sbjct: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
Query: 76 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 135
P PEV WF + +R Y++ G+ L + D Y+C A N+ G+ +C+
Sbjct: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
Query: 136 ELIVETM 142
L VE +
Sbjct: 501 TLQVERL 507
Score = 52.4 bits (124), Expect = 2e-07
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1150
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
Score = 45.4 bits (106), Expect = 2e-05
Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 2/124 (1%)
Query: 18 TSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD 77
T E S +V + V E +P+F R + G + C I G P
Sbjct: 690 TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 749
Query: 78 PEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
P V W +D +++ +++ HF++ +ED +L++ V +Y N +GE +C
Sbjct: 750 PTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
Query: 137 LIVE 140
L+++
Sbjct: 809 LMLQ 812
Score = 32.7 bits (73), Expect = 0.13
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
Query: 104 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ I++ + CG YT N LG L V
Sbjct: 1293 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1327
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 313 bits (802), Expect = 4e-86
Identities = 154/154 (100%), Positives = 154/154 (100%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60
MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1761 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1820
Query: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 1821 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1880
Query: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1881 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914
Score = 71.6 bits (174), Expect = 2e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I V +D KYTC+A N G T EL VE
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 68.6 bits (166), Expect = 2e-12
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 2/119 (1%)
Query: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
E + +L VA KP P F + + DL+V++GS ++ G P PEV+W +
Sbjct: 602 EKKSSRKSEYLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 145
I+ES F + SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 661 NEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718
Score = 62.0 bits (149), Expect = 2e-10
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 36 FLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 91
F E +P + P F+ + + V EG RF CKI G P P+V W K + ++
Sbjct: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
Query: 92 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 204 SARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 60.5 bits (145), Expect = 6e-10
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 567
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Score = 58.5 bits (140), Expect = 2e-09
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 18 TSPLNAEKLESEEDVSQAFLEAVAEE--KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 75
T P L S++ VS+A + E + P F + EV E +F C++ G
Sbjct: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
Query: 76 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 135
P PEV WF + +R Y++ G+ L + D Y+C A N+ G+ +C+
Sbjct: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
Query: 136 ELIVETM 142
L VE +
Sbjct: 501 TLQVERL 507
Score = 52.4 bits (124), Expect = 2e-07
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1150
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
Score = 45.4 bits (106), Expect = 2e-05
Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 2/124 (1%)
Query: 18 TSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD 77
T E S +V + V E +P+F R + G + C I G P
Sbjct: 690 TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 749
Query: 78 PEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
P V W +D +++ +++ HF++ +ED +L++ V +Y N +GE +C
Sbjct: 750 PTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
Query: 137 LIVE 140
L+++
Sbjct: 809 LMLQ 812
Score = 32.7 bits (73), Expect = 0.13
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
Query: 104 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ I++ + CG YT N LG L V
Sbjct: 1293 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1327
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 313 bits (802), Expect = 4e-86
Identities = 154/154 (100%), Positives = 154/154 (100%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60
MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1641 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1700
Query: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 1701 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1760
Query: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1761 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
Score = 71.6 bits (174), Expect = 2e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I V +D KYTC+A N G T EL VE
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 68.6 bits (166), Expect = 2e-12
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 2/119 (1%)
Query: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
E + +L VA KP P F + + DL+V++GS ++ G P PEV+W +
Sbjct: 533 EKKSSRKSEYLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 145
I+ES F + SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 592 NEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 649
Score = 62.0 bits (149), Expect = 2e-10
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 36 FLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 91
F E +P + P F+ + + V EG RF CKI G P P+V W K + ++
Sbjct: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
Query: 92 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 204 SARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 60.5 bits (145), Expect = 6e-10
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 498
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 52.4 bits (124), Expect = 2e-07
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1081
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
Score = 45.4 bits (106), Expect = 2e-05
Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 2/124 (1%)
Query: 18 TSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD 77
T E S +V + V E +P+F R + G + C I G P
Sbjct: 621 TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
Query: 78 PEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
P V W +D +++ +++ HF++ +ED +L++ V +Y N +GE +C
Sbjct: 681 PTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
Query: 137 LIVE 140
L+++
Sbjct: 740 LMLQ 743
Score = 32.7 bits (73), Expect = 0.13
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 1164 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1223
Query: 104 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ I++ + CG YT N LG L V
Sbjct: 1224 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1258
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 313 bits (802), Expect = 4e-86
Identities = 154/154 (100%), Positives = 154/154 (100%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60
MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1692 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1751
Query: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 1752 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1811
Query: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1812 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1845
Score = 71.6 bits (174), Expect = 2e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I V +D KYTC+A N G T EL VE
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 68.6 bits (166), Expect = 2e-12
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 2/119 (1%)
Query: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
E + +L VA KP P F + + DL+V++GS ++ G P PEV+W +
Sbjct: 533 EKKSSRKSEYLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 145
I+ES F + SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 592 NEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 649
Score = 62.0 bits (149), Expect = 2e-10
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 36 FLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 91
F E +P + P F+ + + V EG RF CKI G P P+V W K + ++
Sbjct: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
Query: 92 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 204 SARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 60.5 bits (145), Expect = 6e-10
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 498
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 52.4 bits (124), Expect = 2e-07
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1081
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
Score = 45.4 bits (106), Expect = 2e-05
Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 2/124 (1%)
Query: 18 TSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD 77
T E S +V + V E +P+F R + G + C I G P
Sbjct: 621 TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
Query: 78 PEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
P V W +D +++ +++ HF++ +ED +L++ V +Y N +GE +C
Sbjct: 681 PTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
Query: 137 LIVE 140
L+++
Sbjct: 740 LMLQ 743
Score = 32.7 bits (73), Expect = 0.13
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 1164 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1223
Query: 104 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ I++ + CG YT N LG L V
Sbjct: 1224 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1258
>gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens]
Length = 153
Score = 306 bits (785), Expect = 3e-84
Identities = 153/154 (99%), Positives = 153/154 (99%), Gaps = 1/154 (0%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60
MAMISGLSGRKSSTGSPTSPLNAEKLESE DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 59
Query: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 60 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 119
Query: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 120 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 85.1 bits (209), Expect = 2e-17
Identities = 44/108 (40%), Positives = 61/108 (56%), Gaps = 4/108 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F + D+EV G ARF +EG P P+++W+KD+ + ES H Y+E+ CSL+
Sbjct: 1485 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEEN-ECSLV 1543
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 153
+ D YTC A N GE +C AEL V +T E EG GE+E+
Sbjct: 1544 VLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDED 1591
Score = 78.2 bits (191), Expect = 3e-15
Identities = 41/97 (42%), Positives = 59/97 (60%), Gaps = 1/97 (1%)
Query: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
+P + P F++ + D+EV+EG AARFDCKI G P P V W + ES + ++ D G
Sbjct: 1059 RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQD-GG 1117
Query: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
SL I+ V +D+ Y AVN+ G+A C+A+L VE
Sbjct: 1118 LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154
Score = 57.0 bits (136), Expect = 6e-09
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 11 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 70
K PTSP +LES +D + A E+P P F ++++ V G+ C
Sbjct: 693 KGRRARPTSP----ELESSDDSYVS-----AGEEPLEAPVFEIPLQNVVVAPGADVLLKC 743
Query: 71 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 130
I P P+V W KD ++R + + + + +L++ + D Y A N LG+
Sbjct: 744 IITANPPPQVSWHKDGSALRSEGRLLLRAEGERH-TLLLREARAADAGSYMATATNELGQ 802
Query: 131 ATCTAELIV 139
ATC A L V
Sbjct: 803 ATCAASLTV 811
Score = 55.1 bits (131), Expect = 2e-08
Identities = 32/96 (33%), Positives = 42/96 (43%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F ++ D V EG +++G P P V W ++ Q +R + + E G C L
Sbjct: 869 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I D YTCKAVN G C A L V E
Sbjct: 929 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPE 964
Score = 48.5 bits (114), Expect = 2e-06
Identities = 26/85 (30%), Positives = 43/85 (50%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
++D++V G A F+C + G D EV W + ++ + + + C L+++ V
Sbjct: 974 LQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHE 1033
Query: 115 DDDAKYTCKAVNSLGEATCTAELIV 139
DD YTCK + E TC+A L V
Sbjct: 1034 DDSGVYTCKLSTAKDELTCSARLTV 1058
Score = 48.5 bits (114), Expect = 2e-06
Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 10/140 (7%)
Query: 11 KSSTGSPTSPLNAEKLES-EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFD 69
+++ P+S L EK+ S E+ Q LE ++ P F + ++DLEV A +
Sbjct: 1157 RTAASGPSSKL--EKMPSIPEEPEQGELERLSI------PDFLRPLQDLEVGLAKEAMLE 1208
Query: 70 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 129
C++ G P P + WF + I+ S ++ D + L+ V Y N LG
Sbjct: 1209 CQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVH-RLVFPAVGPQHAGVYKSVIANKLG 1267
Query: 130 EATCTAELIVETMEEGEGEG 149
+A C A L V + G +G
Sbjct: 1268 KAACYAHLYVTDVVPGPPDG 1287
Score = 46.6 bits (109), Expect = 8e-06
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F + +++ V GS R + G P P + WF+D Q + + +C +
Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPA-------PEPSCLWL 95
Query: 109 ISDVCGDDDA-KYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 153
CG DA Y+C A N G A+C A L V +E G+ E E++
Sbjct: 96 RR--CGAQDAGVYSCMAQNERGRASCEAVLTV--LEVGDSETAEDD 137
Score = 44.7 bits (104), Expect = 3e-05
Identities = 28/91 (30%), Positives = 38/91 (41%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F ++D ++EG AA C P P + W KD +S+R I +DG L
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
I Y C A N LG T + + V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 32.0 bits (71), Expect = 0.22
Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 13/101 (12%)
Query: 60 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH--FQIDYDEDGNCSLIISDVCGDDD 117
VVEG A + + +VVW ++ E+R +++ +D L I V D
Sbjct: 1401 VVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDM 1459
Query: 118 AKYTCKAVNSLGEATCTA----------ELIVETMEEGEGE 148
TC A N G TC+ E I+E +E G GE
Sbjct: 1460 GALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGE 1500
>gi|153792294 myopalladin [Homo sapiens]
Length = 1320
Score = 81.6 bits (200), Expect = 2e-16
Identities = 38/97 (39%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYDEDGNC 105
+ P F K ++ V EGS F CKI G P P+V WFKD + I + + H ++ + DG C
Sbjct: 943 IAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTC 1002
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
SL I DDD YT A N G +C+ L+V+++
Sbjct: 1003 SLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSL 1039
Score = 64.3 bits (155), Expect = 4e-11
Identities = 32/108 (29%), Positives = 57/108 (52%), Gaps = 7/108 (6%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-------DYDE 101
P F+K +++L EG F+C+++G P P+V W+++ I +S F+I +
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 102 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 149
+ C+L+I++V +D +TC A N G + A+L V E+ G
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNG 542
Score = 63.5 bits (153), Expect = 7e-11
Identities = 35/114 (30%), Positives = 60/114 (52%), Gaps = 3/114 (2%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 101
EE P F++ +R EV EG+ + DC + G P P+V W+ + + + S I +
Sbjct: 262 EEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI--VQ 319
Query: 102 DGNC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
GN SL I++ +D +Y+C A N G + +AE+ +E + + EG+ +E
Sbjct: 320 AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKE 373
Score = 56.6 bits (135), Expect = 8e-09
Identities = 30/96 (31%), Positives = 45/96 (46%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
+P+F + D+ EG R DCK+ G P PE+ W + Q + ++ E G SL
Sbjct: 1072 RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSL 1131
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
+I + D Y C A N G+ + + EL V E
Sbjct: 1132 LIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167
Score = 50.8 bits (120), Expect = 4e-07
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 37 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR-HF 95
L VA+E P + +++ V EG R +C++ G P P W KD+++I +R
Sbjct: 1161 LSVVAKEVKKA-PVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERI 1219
Query: 96 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 137
+ D G L+I D YT A N G +CTA L
Sbjct: 1220 SMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARL 1261
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 79.3 bits (194), Expect = 1e-15
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 29 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 88
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1272 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1330
Query: 89 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1331 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382
Score = 76.3 bits (186), Expect = 1e-14
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 12 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 70
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 905 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964
Query: 71 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 130
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 965 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023
Query: 131 ATCTAELIVETMEEGEGE 148
+ + L V+ EE E E
Sbjct: 1024 VSTSCYLAVQVSEEFEKE 1041
Score = 70.1 bits (170), Expect = 7e-13
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 106
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 67.8 bits (164), Expect = 4e-12
Identities = 41/122 (33%), Positives = 58/122 (47%), Gaps = 5/122 (4%)
Query: 22 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 81
N + E E+ + LE + P F I D ++ E S A F C + G P PEV
Sbjct: 5358 NMDSREGEDKELKIDLEVF-----EMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVK 5412
Query: 82 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 141
W+K+ I + +E G+ +L I +VC D A Y C+AVN +GEA C L +
Sbjct: 5413 WYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGD 5472
Query: 142 ME 143
E
Sbjct: 5473 SE 5474
Score = 67.4 bits (163), Expect = 5e-12
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 28 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 87
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 88 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 63.2 bits (152), Expect = 9e-11
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172
Score = 61.6 bits (148), Expect = 3e-10
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
II D ++T A N G ++ + L VE +E
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1551
Score = 60.8 bits (146), Expect = 4e-10
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 101
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3338 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3396
Query: 102 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 153
D L I++ +D+ YT A N++G+ + TA L +E E E E+E
Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447
Score = 60.5 bits (145), Expect = 6e-10
Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 4/114 (3%)
Query: 24 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWF 83
E+L + + + +F E E P P F K I D G+AA F C + G P P V W+
Sbjct: 5492 EELVLKSNYTDSFFEFQVVEGP---PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWY 5548
Query: 84 KDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 137
KD + + + R F ++ G +L I+ + D+ +Y C A N G A A L
Sbjct: 5549 KDGKLV-QGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 5601
Score = 58.9 bits (141), Expect = 2e-09
Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 1/129 (0%)
Query: 16 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 75
S ++ ++ K E +E+ + F + + P F + I EV EG + F C +GY
Sbjct: 3911 SASTRIDEFKTEQKEENMRFFENSFRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGY 3970
Query: 76 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 135
P P V W+ +D I +++F I + + L +S V ++ TC N G T+
Sbjct: 3971 PQPIVTWYNNDMPIPRNQNF-IIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTS 4029
Query: 136 ELIVETMEE 144
L V+ ++
Sbjct: 4030 MLKVKAKQK 4038
Score = 57.8 bits (138), Expect = 4e-09
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 107
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1082 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1141
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+IS DD +YT N GE + +A L+ E
Sbjct: 1142 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1174
Score = 57.4 bits (137), Expect = 5e-09
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 107
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3296
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Score = 57.4 bits (137), Expect = 5e-09
Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 8/107 (7%)
Query: 36 FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 95
FL + E P + K R EG + +C I G P P V WF++ +++++ F
Sbjct: 4149 FLSDITNEPPKMLQEMPKHAR---CREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKF 4205
Query: 96 QIDYDEDGNCS--LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
Q E+ NCS L I DV D KY C A N+ G ++L VE
Sbjct: 4206 QF---EEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVE 4249
Score = 55.8 bits (133), Expect = 1e-08
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 17 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 74
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1807 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1866
Query: 75 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 134
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1867 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1924
Query: 135 AELIVETMEE 144
+L ++ E+
Sbjct: 1925 VKLEIQQRED 1934
Score = 54.3 bits (129), Expect = 4e-08
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 37 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 96
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1547 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1603
Query: 97 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1604 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1659
Score = 53.1 bits (126), Expect = 9e-08
Identities = 32/108 (29%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
EA+ + + P F + + +V E + F ++EG P P V W+++ + +I
Sbjct: 5172 EAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDE--RI 5229
Query: 98 DYDEDGN-CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
+ GN CSL IS++ + +Y C AVN +GEA A + + EE
Sbjct: 5230 KMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEE 5277
Score = 50.1 bits (118), Expect = 8e-07
Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 46 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED--- 102
+ KP F++ + V+EG F C++ P PE+ WF +++ I I + D
Sbjct: 3501 YFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHH 3560
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 148
+ SL I V D Y A+NS G A TA L+V +++G+ E
Sbjct: 3561 HSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV--IQKGQDE 3604
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 99
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1754
Query: 100 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+E G CSL D TC+A N G +A LIV+
Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1795
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3054 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ L+I D KYT A G TA+L VE
Sbjct: 3111 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3143
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 50 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2883 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2940
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 153
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2941 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2984
Score = 32.7 bits (73), Expect = 0.13
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2362 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2419
Query: 115 DDDAKYTCKAVNSLGEAT 132
+D Y+ + +LG +T
Sbjct: 2420 EDAGNYSF-TIPALGLST 2436
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 51 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2233
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ D Y+C V T TA+LIVE
Sbjct: 2234 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2263
Score = 30.8 bits (68), Expect = 0.48
Identities = 12/42 (28%), Positives = 23/42 (54%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 96
++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2492
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 79.3 bits (194), Expect = 1e-15
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 29 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 88
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1272 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1330
Query: 89 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1331 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382
Score = 76.3 bits (186), Expect = 1e-14
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 12 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 70
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 905 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964
Query: 71 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 130
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 965 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023
Query: 131 ATCTAELIVETMEEGEGE 148
+ + L V+ EE E E
Sbjct: 1024 VSTSCYLAVQVSEEFEKE 1041
Score = 70.1 bits (170), Expect = 7e-13
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 106
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 67.4 bits (163), Expect = 5e-12
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 28 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 87
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 88 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 65.9 bits (159), Expect = 1e-11
Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 15/113 (13%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P+F + ++ V G +A F+C + G +V W KD + IR +QI Y E+ + L
Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLEN-SAHLT 8211
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAEL--------------IVETMEEGEG 147
+ V D +YTC AVN +G+ +CTA+L + ET+EE EG
Sbjct: 8212 VLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEG 8264
Score = 65.5 bits (158), Expect = 2e-11
Identities = 35/94 (37%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
+ P+F+K +R+++ V R DCKI G V WFKD + I S ++I + E G S
Sbjct: 4111 IAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE-GTAS 4169
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L I V +D +TC+A NS+G + LIV+
Sbjct: 4170 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ 4203
Score = 64.3 bits (155), Expect = 4e-11
Identities = 31/114 (27%), Positives = 63/114 (55%), Gaps = 7/114 (6%)
Query: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
E+ +D+ +A + + PYF + + +E V G A CK++G P+ + W+K+
Sbjct: 7004 EAGQDICEALVSVLEP------PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEH 7057
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+R + +++ + ++ SL+I+ V D +Y+CKA NS+G +A L+++
Sbjct: 7058 TKLRSAPAYKMQF-KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK 7110
Score = 63.2 bits (152), Expect = 9e-11
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172
Score = 62.8 bits (151), Expect = 1e-10
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
+ P F+K ++ ++ ++GS +C + G + WFKDDQ I S ++ + D
Sbjct: 4673 IPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSF-HDNTAF 4731
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L IS + G D YTC A N G C+ L V+
Sbjct: 4732 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 4765
Score = 61.6 bits (148), Expect = 3e-10
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
II D ++T A N G ++ + L VE +E
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1551
Score = 61.2 bits (147), Expect = 3e-10
Identities = 27/81 (33%), Positives = 51/81 (62%), Gaps = 1/81 (1%)
Query: 60 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 119
++ G +AR CK++G P +V WFK+++ + ES ++ Y + L I+DV +D
Sbjct: 3749 MLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRM-YFVNSEAILDITDVKVEDSGS 3807
Query: 120 YTCKAVNSLGEATCTAELIVE 140
Y+C+AVN +G +C+ E++++
Sbjct: 3808 YSCEAVNDVGSDSCSTEIVIK 3828
Score = 60.8 bits (146), Expect = 4e-10
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 101
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3338 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3396
Query: 102 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 153
D L I++ +D+ YT A N++G+ + TA L +E E E E+E
Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447
Score = 59.3 bits (142), Expect = 1e-09
Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
PYF K + ++V G +A C++ G P+ V W+K D +R + +++ + + +L+
Sbjct: 7961 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHF-RNNVATLV 8019
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ V +D +Y CKA NS+GE + + L V+
Sbjct: 8020 FNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051
Score = 58.9 bits (141), Expect = 2e-09
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 2/128 (1%)
Query: 12 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 71
++ G +S N LE+ E + +E E + P + I LEV G A+F C+
Sbjct: 3420 NAVGQVSSTANLS-LEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCE 3478
Query: 72 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 131
I+ P+ WFK + I ES I + + SL I D +YTCKA N G
Sbjct: 3479 IQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSV 3537
Query: 132 TCTAELIV 139
+CTA L V
Sbjct: 3538 SCTATLTV 3545
Score = 57.8 bits (138), Expect = 4e-09
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 107
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1082 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1141
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+IS DD +YT N GE + +A L+ E
Sbjct: 1142 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1174
Score = 57.8 bits (138), Expect = 4e-09
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
V P F++ +++ + GS+ +CK+ G P V WF + I R +Q D C+
Sbjct: 7680 VPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTL-TDNTCA 7738
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L ++ + D YTC A N G C+A L V
Sbjct: 7739 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 7771
Score = 57.8 bits (138), Expect = 4e-09
Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 62 EGSAARFDCKIEGYPDP-EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
EG ++ CKIE Y +V W+ + + S ++I Y EDG L + D+ DD Y
Sbjct: 31581 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTY 31639
Query: 121 TCKAVNSLGEATCTAELIVETMEE 144
CK VN GE + AEL V+ + E
Sbjct: 31640 RCKVVNDYGEDSSYAELFVKGVRE 31663
Score = 57.8 bits (138), Expect = 4e-09
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 30 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 31773 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 31832
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 31833 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892
Query: 147 GEGEEEEE 154
E + +EE
Sbjct: 31893 QEFKSKEE 31900
Score = 57.4 bits (137), Expect = 5e-09
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 107
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3296
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Score = 57.4 bits (137), Expect = 5e-09
Identities = 28/93 (30%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Query: 49 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
P F K + +V +G + + +CKI G P+ +V WF++D + ES + + + + L
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF-INSVALL 6422
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I++ +D Y C+A N +G+A+C+ L V+
Sbjct: 6423 TINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455
Score = 57.4 bits (137), Expect = 5e-09
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F K +E ++G+ +C+++G P V W+KD + +R + ++I E+ S+
Sbjct: 7399 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MSENFLTSIH 7457
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I +V D +Y CKA N +G TC + ++
Sbjct: 7458 ILNVDAADIGEYQCKATNDVGSDTCVGSIALK 7489
Score = 57.0 bits (136), Expect = 6e-09
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
PYF + LE G + C++ G P+ V W+K D +R + ++ Y + +L+
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYR-TYFTNNVATLV 6137
Query: 109 ISDVCGDDDAKYTCKAVNSLGEAT 132
+ V +D +YTCKA NS+G A+
Sbjct: 6138 FNKVNINDSGEYTCKAENSIGTAS 6161
Score = 57.0 bits (136), Expect = 6e-09
Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
Query: 49 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
P F K + +V + R++CKI G P+ +V+W+KD+ I+ES F++ + D L
Sbjct: 7305 PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF-VDSVAVL 7363
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ ++ +D YTC+A N+ G A+ + L V+
Sbjct: 7364 EMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396
Score = 56.2 bits (134), Expect = 1e-08
Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F++ + ++GS C+I G P EVVW KD + +R S+ F+I + + SL
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKIT-SKHFDTSLH 6516
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 137
I ++ D +Y CKA N +G TC+ +
Sbjct: 6517 ILNLEASDVGEYHCKATNEVGSDTCSCSV 6545
Score = 56.2 bits (134), Expect = 1e-08
Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Query: 31 DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 90
+VS + V E+K + P FS+ +RD++ G FDC I G V W+KD + ++
Sbjct: 8041 EVSASTFLTVQEQK--LPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLK 8098
Query: 91 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+S + Q + D +L I +Y+C A N +G A+ +A LI+
Sbjct: 8099 DSPNVQTSF-LDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 8146
Score = 55.8 bits (133), Expect = 1e-08
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 17 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 74
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1807 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1866
Query: 75 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 134
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1867 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1924
Query: 135 AELIVETMEE 144
+L ++ E+
Sbjct: 1925 VKLEIQQRED 1934
Score = 55.5 bits (132), Expect = 2e-08
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F + L G AA+F C + G P E +W KD ++ S +++I D + L
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRIS-DAENKHILE 3609
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+S++ D Y+CKA N G C AELI+
Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADICQAELII 3640
Score = 55.5 bits (132), Expect = 2e-08
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
+P P+F ++V+ G +A F+C + G + W KD++ IR ++ I G
Sbjct: 6266 EPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITC--VG 6323
Query: 104 NC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
N L I V D +YTC+A N +G+ C+A+L V+
Sbjct: 6324 NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVK 6361
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 45 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 103
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 30924 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 30983
Query: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
LII+ V DD Y +A N G + TA L VE
Sbjct: 30984 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 31020
Score = 55.5 bits (132), Expect = 2e-08
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 33192
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I + D KYT KA N G+ + TA L+V + E
Sbjct: 33193 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 33228
Score = 55.1 bits (131), Expect = 2e-08
Identities = 29/95 (30%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 46 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 105
++ P F+K + ++ V GS+ +CK+ G WFKD + I S +++ E +
Sbjct: 5234 NIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHE-RSV 5292
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
SL ++++ +D A YTCK N G+ C+ L V+
Sbjct: 5293 SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327
Score = 55.1 bits (131), Expect = 2e-08
Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 1/85 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P FS +E ++ + +C++ G P EVVW+KD + +R S+ ++I ++ + S+
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKI-ASKNFHTSIH 5575
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATC 133
I +V D +Y CKA N +G TC
Sbjct: 5576 ILNVDTSDIGEYHCKAQNEVGSDTC 5600
Score = 54.3 bits (129), Expect = 4e-08
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 37 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 96
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1547 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1603
Query: 97 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1604 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1659
Score = 54.3 bits (129), Expect = 4e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 105
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 31748
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 31749 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 53.9 bits (128), Expect = 5e-08
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 32841 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 32900
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 148
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 32901 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 32950
Score = 53.5 bits (127), Expect = 7e-08
Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
PYF+K + +EV++ ++ G P E+ WFKD+ +R R ++ + +D SL
Sbjct: 4393 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYK-TFIQDHLVSLQ 4451
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 137
I D +Y C+ N +G + C+A +
Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARV 4480
Score = 53.5 bits (127), Expect = 7e-08
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 6/110 (5%)
Query: 37 LEAVAEEKPHVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 95
LE AE + +P F+K I+++ V E +A F+C++ + D V W+K + ES+ +
Sbjct: 8821 LETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEV-SFDDAIVTWYKGPTELTESQKY 8879
Query: 96 QIDYDEDGNCS-LIISDVCGDDDAKYTCKA-VNSLGEATCTAELIVETME 143
++ DG C + I +V DD+ Y+ A + GEA TAEL + T E
Sbjct: 8880 --NFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKE 8927
Score = 53.1 bits (126), Expect = 9e-08
Identities = 25/93 (26%), Positives = 54/93 (58%), Gaps = 2/93 (2%)
Query: 49 PYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
P F K + ++V+ G ++R +CKI G P+ VVWF+++ + S +++ + D +
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF-IDSVAVI 5481
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
++++ +D + C+A N G +C+ ++IV+
Sbjct: 5482 QMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514
Score = 53.1 bits (126), Expect = 9e-08
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 30592
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+++ +D+ YTC A N +GE +++L+++
Sbjct: 30593 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 30623
Score = 52.8 bits (125), Expect = 1e-07
Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
+G A + CK+ G P ++ WF +D+ I+ES ++ + E L ++DV +D +Y
Sbjct: 4313 KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVE-STAVLRLTDVGIEDSGEYM 4371
Query: 122 CKAVNSLGEATCTAELIVE 140
C+A N G C++ +IV+
Sbjct: 4372 CEAQNEAGSDHCSSIVIVK 4390
Score = 52.8 bits (125), Expect = 1e-07
Identities = 37/113 (32%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 28 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 87
S E S + VA ++P P F K I + V S+A F + G P + W KDDQ
Sbjct: 5030 SNEGGSCSCSTRVALKEP---PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQ 5086
Query: 88 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ E + I + D +L I V +YTC+A N G C A L+V+
Sbjct: 5087 ILDEDDNVYISF-VDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138
Score = 52.4 bits (124), Expect = 2e-07
Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F KT+ ++V G+ A C++ G E+ WFKD + IR S+ +++ + + L
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRL-FSQKSLVCLE 3889
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTA 135
I D +Y C N +G+ C A
Sbjct: 3890 IFSFNSADVGEYECVVANEVGKCGCMA 3916
Score = 52.4 bits (124), Expect = 2e-07
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 21 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 80
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 22121 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 22179
Query: 81 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 22180 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 22237
Score = 51.6 bits (122), Expect = 3e-07
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
+ ++V E +C + G P+ +V W KD + I SR+F + + E+ S I V
Sbjct: 5148 KSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSF-ENNVASFRIQSVMKQ 5206
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
D +YT K N G ++C A L V
Sbjct: 5207 DSGQYTFKVENDFGSSSCDAYLRV 5230
Score = 51.2 bits (121), Expect = 3e-07
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
V P F + ++D+ + G++ +C++ G V WF+D I Q + E+ C+
Sbjct: 6739 VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCT 6797
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L +S + D YTC A N G C+A L V+
Sbjct: 6798 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 6831
Score = 51.2 bits (121), Expect = 3e-07
Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 107
P F K + D+ V G + IEG VVWFKD + +RES + I Y E+ +L
Sbjct: 7492 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSEN-IATL 7550
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
S V + KYTC+ N G C A L V
Sbjct: 7551 QFSRVEPANAGKYTCQIKNDAGMQECFATLSV 7582
Score = 50.8 bits (120), Expect = 4e-07
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
V P F++ +++ V G++ +CK+ G V WF + I +Q + D C+
Sbjct: 5798 VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF-SDNVCT 5856
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L ++ + D YTC A N G C A L V+
Sbjct: 5857 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQ 5890
Score = 50.4 bits (119), Expect = 6e-07
Identities = 31/92 (33%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F K + DL + G + G V W K + IRE ++ + +G LI
Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGVAVLI 3982
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I DV KYTC A N G T ELIV+
Sbjct: 3983 IPDVQISFGGKYTCLAENEAGSQTSVGELIVK 4014
Score = 50.4 bits (119), Expect = 6e-07
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 33 SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 92
S A L A + P P+F++ ++D+ G F+C+I G +V W+KD +++
Sbjct: 7103 SSAVLVIKARKLP---PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDD 7159
Query: 93 RHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
+ Q + + +L I +Y C A N LG A+ +A+LI+ E
Sbjct: 7160 ANLQTSFVHN-VATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 7209
Score = 49.7 bits (117), Expect = 1e-06
Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
V P+F +++ G + F C + G ++ W KD++ IR ++++ E+ +
Sbjct: 7210 VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVEN-TAT 7268
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L + V D +YTC A N G+ +C+A+L V+
Sbjct: 7269 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 7302
Score = 49.3 bits (116), Expect = 1e-06
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F K I + G A F ++G V W KD I E + ++ + E+ SL
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF-ENNVASLY 4544
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+S + D KY C+A N G C+A L V+
Sbjct: 4545 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK 4576
Score = 49.3 bits (116), Expect = 1e-06
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 101
E K P F + ++ +EVV+ S +C++ G P EV W K+++ IR S+ + + D
Sbjct: 4948 ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLT-DR 5006
Query: 102 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+L I+ D +Y C N G +C+ + ++
Sbjct: 5007 VSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK 5045
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 99
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1754
Query: 100 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+E G CSL D TC+A N G +A LIV+
Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1795
Score = 47.8 bits (112), Expect = 4e-06
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F K LEV+ G F I G P +V WF+ + + + I Y ED L
Sbjct: 5893 PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNI-YFEDTVAELE 5951
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ ++ +YTC N+ G+A+CT L V+
Sbjct: 5952 LFNIDISQSGEYTCVVSNNAGQASCTTRLFVK 5983
Score = 47.4 bits (111), Expect = 5e-06
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
++ + P F++ ++D+E G C++ G +V W++D +R+ + Q + D
Sbjct: 6169 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSF-VD 6227
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 137
+L I +Y+C A N LG A+ +A L
Sbjct: 6228 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 6262
Score = 47.4 bits (111), Expect = 5e-06
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 22 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 81
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 27932 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 27991
Query: 82 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 27992 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049
Score = 46.2 bits (108), Expect = 1e-05
Identities = 23/95 (24%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 47 VKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 105
+ P F+K + + +E EG++ + + ++ G V W+K++ I+ + + +I + ++
Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF-KNNTL 8305
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L + +D YTCK N G A CT+ ++++
Sbjct: 8306 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 8340
Score = 46.2 bits (108), Expect = 1e-05
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 8 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 62
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 32681 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 32740
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 32741 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 32791
Query: 123 K 123
+
Sbjct: 32792 E 32792
Score = 45.8 bits (107), Expect = 1e-05
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 107
P F K + D + G A +EG+ VVW KD + IRES + +I + D +L
Sbjct: 6551 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISF-IDNIATL 6609
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ + KY C+ N G C+A L V
Sbjct: 6610 QLGSPEASNSGKYICQIKNDAGMRECSAVLTV 6641
Score = 45.8 bits (107), Expect = 1e-05
Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
Query: 39 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 98
++ ++P P F + + + V EG + C ++G + W K + I+ S
Sbjct: 8336 SIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFS 8395
Query: 99 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ G L + DV D Y CKA N G T +++ ++
Sbjct: 8396 F-ASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 8436
Score = 45.8 bits (107), Expect = 1e-05
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 45 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 104
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 12372 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 12427
Query: 105 CSLIISDVCGDDDAKYTCK 123
L+I+ DD+A+Y+C+
Sbjct: 12428 RILVINKCLLDDEAEYSCE 12446
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3054 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ L+I D KYT A G TA+L VE
Sbjct: 3111 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3143
Score = 45.4 bits (106), Expect = 2e-05
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F +T +EV+ G + F I G P +V WFK + + I ED L
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISL-EDFVTELE 6892
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ +V + Y+C N G A+CT L V+
Sbjct: 6893 LFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924
Score = 45.1 bits (105), Expect = 2e-05
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
G + F+C+I G P V W+ D I + I + DG + IS ++ Y C
Sbjct: 4876 GQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFI-DGLATFQISGARVENSGTYVC 4934
Query: 123 KAVNSLGEATCTAELIVE 140
+A N G A+C+ EL V+
Sbjct: 4935 EARNDAGTASCSIELKVK 4952
Score = 44.3 bits (103), Expect = 4e-05
Identities = 36/124 (29%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 24 EKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTI----RDLEVVEGSAARFDCKIEGYP 76
E S E S A E EEK +K + I R + V EG +ARF C +G P
Sbjct: 32529 EHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEP 32588
Query: 77 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
P V W + Q + S Q+ + + IS V D+ Y+ NS G+
Sbjct: 32589 VPTVTWLRKGQVLSTSARHQVTTTK-YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFT 32647
Query: 137 LIVE 140
L ++
Sbjct: 32648 LTIQ 32651
Score = 43.9 bits (102), Expect = 5e-05
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
+ V G +CK+ G P+ V W+KD + + S+ + + + SL I V D
Sbjct: 5713 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLRILSVERQDA 5771
Query: 118 AKYTCKAVNSLGEATCTA 135
YT + N++G+++CTA
Sbjct: 5772 GTYTFQVQNNVGKSSCTA 5789
Score = 43.9 bits (102), Expect = 5e-05
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
++V G +C + G P+ WFKD + + ++I + + L I +V D
Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS-GLKIINVAPSDS 7653
Query: 118 AKYTCKAVNSLGEATCTAELIV 139
Y+ + N +G+ +CTA L V
Sbjct: 7654 GVYSFEVQNPVGKDSCTASLQV 7675
Score = 43.9 bits (102), Expect = 5e-05
Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F + ++V+ G+ F ++G P V WFK + + ED L
Sbjct: 7775 PSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSL-EDSVAELE 7833
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ DV +YTC N G+A+CT L ++
Sbjct: 7834 LFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 7865
Score = 43.5 bits (101), Expect = 7e-05
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
KP+F K + ++ +C+++ V W KD Q + + ++I + ED +L
Sbjct: 3643 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICF-EDKIATL 3701
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
I D Y C A N G ++C+A + V
Sbjct: 3702 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 3733
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 50 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2883 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2940
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 153
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2941 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2984
Score = 43.1 bits (100), Expect = 9e-05
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 110
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 16126 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 16184
Query: 111 DVCGDDDAKYTCKAVNSLGEAT 132
D YT AVN+LG A+
Sbjct: 16185 QSRRSDTGLYTITAVNNLGTAS 16206
Score = 43.1 bits (100), Expect = 9e-05
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 18888 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 18947
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 18948 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988
Score = 43.1 bits (100), Expect = 9e-05
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 22 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 78
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 22517 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 22573
Query: 79 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 22574 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 22632
Query: 139 V 139
V
Sbjct: 22633 V 22633
Score = 42.7 bits (99), Expect = 1e-04
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 51 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 104
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 11117 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 11174
Query: 105 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
+I DV D +YTC E T TA+L+VE +
Sbjct: 11175 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210
Score = 42.4 bits (98), Expect = 2e-04
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 23229 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 23283
Query: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
+L I + DD +Y N +G+ T + E++
Sbjct: 23284 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 23318
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 12522
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 153
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 12523 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 12570
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 104
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 33385
Query: 105 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
+LII DV D YT N G + T + + ++
Sbjct: 33386 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 33423
Score = 41.2 bits (95), Expect = 4e-04
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 17515 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 17573
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIV 139
D +Y N+ G T L V
Sbjct: 17574 LRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 40.8 bits (94), Expect = 5e-04
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F K + D V GS + G P V W KD+ I +S I E I+
Sbjct: 6929 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 6988
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
+D A+Y+C N G+ C E +V +E
Sbjct: 6989 STI-EDYAQYSCLIENEAGQDIC--EALVSVLE 7018
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 13695 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 13753
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIV 139
D Y +AVN G AT E+ V
Sbjct: 13754 KRSDTGTYIIEAVNVCGRATAVVEVNV 13780
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 24310 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 24368
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I + DD KYT A NS G AT +IV
Sbjct: 24369 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401
Score = 40.4 bits (93), Expect = 6e-04
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 12287 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 12344
Query: 111 DVCGDDDAKYTCKA 124
D +D YTC A
Sbjct: 12345 DCTPEDIKTYTCDA 12358
Score = 39.7 bits (91), Expect = 0.001
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 28 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 81
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 11991 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 12049
Query: 82 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 12050 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 12089
Score = 39.3 bits (90), Expect = 0.001
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 14376 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 14435
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
D + L + D YT N LG AT + + V
Sbjct: 14436 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 14476
Score = 38.9 bits (89), Expect = 0.002
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
++V +G A K G + WFKD Q + ++I + + IIS D
Sbjct: 4588 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTE-KKDS 4646
Query: 118 AKYTCKAVNSLGEATCTAELIV 139
+YT + N +G ++C A + V
Sbjct: 4647 GEYTFEVQNDVGRSSCKARINV 4668
Score = 38.9 bits (89), Expect = 0.002
Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 1/81 (1%)
Query: 59 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 118
+ + S F ++G P ++ WFKDD + I E L + V
Sbjct: 5340 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGL-EGSTSFLNLYSVDASKTG 5398
Query: 119 KYTCKAVNSLGEATCTAELIV 139
+YTC N +G +CT L+V
Sbjct: 5399 QYTCHVTNDVGSDSCTTMLLV 5419
Score = 38.9 bits (89), Expect = 0.002
Identities = 36/141 (25%), Positives = 48/141 (34%), Gaps = 29/141 (20%)
Query: 42 EEKPHVKP-----------YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 90
++KP V P +F + + VVE + A F K+ G P P V W K
Sbjct: 8436 KDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL 8495
Query: 91 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE---- 146
+ + L I D D Y C A N GE L V+ ++ E
Sbjct: 8496 NQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEG 8555
Query: 147 --------------GEGEEEE 153
G GEEEE
Sbjct: 8556 DLRAMLKKTPILKKGAGEEEE 8576
Score = 38.5 bits (88), Expect = 0.002
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 23632 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 23690
Query: 115 DDDAKYTCKAVNSLG 129
D +Y +A N G
Sbjct: 23691 IDGGQYILRASNVAG 23705
Score = 38.1 bits (87), Expect = 0.003
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
PYF + + +V + + + G + WFKD++ + + + +D + SL
Sbjct: 4768 PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSV-WKDDTSTSLE 4826
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ D Y C+ N +G AT A L V+
Sbjct: 4827 LFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858
Score = 37.4 bits (85), Expect = 0.005
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 116
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 15170
Query: 117 DAKYTCKAVNSLGEATCTAELIV 139
+Y A NS G A + V
Sbjct: 15171 HGRYVITATNSCGSKFAAARVEV 15193
Score = 37.4 bits (85), Expect = 0.005
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 31 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 87
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 26167 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 26225
Query: 88 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 26226 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 26276
Score = 37.0 bits (84), Expect = 0.007
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 110
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 17913 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 17969
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTA 135
+ D KY A NS G A +A
Sbjct: 17970 EAVRADHGKYIISAKNSSGHAQGSA 17994
Score = 37.0 bits (84), Expect = 0.007
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 40 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 93
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 18187 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 18246
Query: 94 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
++ D + S ++ D KY A N+ G A + V
Sbjct: 18247 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 23008
Query: 118 AKYTCKAVNSLG 129
KYT NS G
Sbjct: 23009 GKYTLTLENSSG 23020
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 49 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 105
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 26928
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCT 134
S++I D + Y K N++G A+ T
Sbjct: 26929 SILIKDADRLNSGCYELKLRNAMGSASAT 26957
Score = 36.6 bits (83), Expect = 0.009
Identities = 17/77 (22%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
++P + + ++D+ + EG C+ P+ + WF++ + ++ + + + +
Sbjct: 8743 IEPAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRILKPQGRHKTEVEHKVH-K 8800
Query: 107 LIISDVCGDDDAKYTCK 123
L I+DV +D +YTCK
Sbjct: 8801 LTIADVRAEDQGQYTCK 8817
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 34 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 90
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 28631 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 28689
Query: 91 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 28690 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 28737
Score = 36.2 bits (82), Expect = 0.011
Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F K + D + +G + G P V W K+ ++ S+ I E + L I
Sbjct: 7870 FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK-SAILEIP 7928
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+D +Y C N+ G+ +C+A++++
Sbjct: 7929 SSTVEDAGQYNCYIENASGKDSCSAQILI 7957
Score = 35.8 bits (81), Expect = 0.015
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 107
P F + L VV G A IEG V W K+ ++ IRES + +I + E+ +L
Sbjct: 5610 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN-VATL 5668
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ + KY C+ N G A L+V
Sbjct: 5669 QFAKAEPANAGKYICQIKNDGGMRENMATLMV 5700
Score = 35.8 bits (81), Expect = 0.015
Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDD 116
+ V G+ +C + G P+ WFKD + + +S+H ++ + + +++ D
Sbjct: 6654 MTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEM--SD 6711
Query: 117 DAKYTCKAVNSLGEATCTAELIV 139
Y+ + NS+G++ CT + V
Sbjct: 6712 KGLYSFEVKNSVGKSNCTVSVHV 6734
Score = 35.8 bits (81), Expect = 0.015
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 73 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 130
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 27296 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 27352
Score = 35.4 bits (80), Expect = 0.019
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 107
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 32374 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 32431
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
I D DD Y N GEA+ A L V
Sbjct: 32432 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463
Score = 35.0 bits (79), Expect = 0.025
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 11842 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 11899
Query: 111 DVCGDDDAKYTCKA 124
+D+AKY +A
Sbjct: 11900 SAAFEDEAKYMFEA 11913
Score = 35.0 bits (79), Expect = 0.025
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 19363
Query: 118 AKYTCKAVNSLGEATCTAELIV 139
YT A NS G + T +L V
Sbjct: 19364 GDYTITAENSSGSKSATIKLKV 19385
Score = 34.7 bits (78), Expect = 0.033
Identities = 18/82 (21%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
++V G A + + G P+ + W+KD + + S+ ++I + ++ L D
Sbjct: 4026 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDS 4084
Query: 118 AKYTCKAVNSLGEATCTAELIV 139
+YT + N +G ++C V
Sbjct: 4085 GQYTFEISNEVGSSSCETTFTV 4106
Score = 34.7 bits (78), Expect = 0.033
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 25393 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 25451
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I + +D Y NS G T +IV
Sbjct: 25452 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 25484
Score = 34.3 bits (77), Expect = 0.043
Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Query: 11 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKT-IRDLE---VVEGSAA 66
K S T L E++E E + F E V+ + + T I+D+E V++ + A
Sbjct: 8614 KQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDA 8673
Query: 67 RFDCKIE-GYPDPEVVWFKDDQSIRESRHFQIDYDED 102
F+ I+ YP+ ++ W+K + + S F+I D D
Sbjct: 8674 VFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGD 8710
Score = 34.3 bits (77), Expect = 0.043
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 12646 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 12703
Query: 115 DDDAKYTCKAVNSLGE-ATCTAELIVE 140
DD A Y N GE A LIVE
Sbjct: 12704 DDQANYNVSLTNHRGENVKSAANLIVE 12730
Score = 34.3 bits (77), Expect = 0.043
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 52 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 111
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 24028 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 24083
Query: 112 VCGDDDA-KYTCKAVNSLG 129
C +DA KY K NS G
Sbjct: 24084 NCDRNDAGKYILKLENSSG 24102
Score = 33.9 bits (76), Expect = 0.057
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 1/82 (1%)
Query: 59 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 118
+V+ GSA +G + WFK ++ + I E SL + V D
Sbjct: 4216 DVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYIT-KEALESSLELYLVKTSDSG 4274
Query: 119 KYTCKAVNSLGEATCTAELIVE 140
YTCK N G C+A L V+
Sbjct: 4275 TYTCKVSNVAGGVECSANLFVK 4296
Score = 33.9 bits (76), Expect = 0.057
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 21534
Query: 123 KAVNSLGEA 131
A N G A
Sbjct: 21535 TATNPGGFA 21543
Score = 33.9 bits (76), Expect = 0.057
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 36 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 85
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 29428 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 29482
Query: 86 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 134
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 29483 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 29529
Score = 33.5 bits (75), Expect = 0.074
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 11576 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 11633
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+V DD ++ + + E + TA+L V
Sbjct: 11634 EVTLDDISQIKAQ----VKELSSTAQLKV 11658
Score = 33.5 bits (75), Expect = 0.074
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 11931 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 11988
Query: 111 DVCGDDDAKYTCKAVNSLGEATCT 134
D+ DD ++ +A+ EA T
Sbjct: 11989 DLSIDDTSQIRVEAMGMSSEAKLT 12012
Score = 33.1 bits (74), Expect = 0.097
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 16 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 61
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 11616 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 11675
Query: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 11676 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 11732
Query: 122 CKAVNSLGEATCTAE 136
C +A T E
Sbjct: 11733 CDCGTDKTKANVTVE 11747
Score = 33.1 bits (74), Expect = 0.097
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 17282
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
D Y+ N G T + +++V
Sbjct: 17283 DGGIYSLTVENPAGSKTVSVKVLV 17306
Score = 32.7 bits (73), Expect = 0.13
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2362 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2419
Query: 115 DDDAKYTCKAVNSLGEAT 132
+D Y+ + +LG +T
Sbjct: 2420 EDAGNYSF-TIPALGLST 2436
Score = 32.7 bits (73), Expect = 0.13
Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F K + D V G + + G V W KD +I S I E C L I
Sbjct: 5988 FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEK-TCILEIL 6046
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
+ D +Y+C+ N G C A +V T+E
Sbjct: 6047 NSTKRDAGQYSCEIENEAGRDVCGA--LVSTLE 6077
Score = 32.7 bits (73), Expect = 0.13
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 121
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 29062 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 29119
Query: 122 CKAVNSLG 129
N+ G
Sbjct: 29120 LTVKNASG 29127
Score = 32.3 bits (72), Expect = 0.16
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 56 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 113
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 12559 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 12614
Query: 114 GDDDAKYTCKAVNSLGEATCTAELIV 139
D Y V +G A A L V
Sbjct: 12615 LQDMGTY----VVMVGAARAAAHLTV 12636
Score = 32.3 bits (72), Expect = 0.16
Identities = 27/111 (24%), Positives = 36/111 (32%), Gaps = 30/111 (27%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQ--------------------SIRESRHF-- 95
LEV G D I G P P + W KD+ ++E F
Sbjct: 14689 LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVL 14748
Query: 96 ------QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATCTAELI 138
ID + G L + D D Y K N G +A CT ++
Sbjct: 14749 PLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 14799
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 51 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2233
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ D Y+C V T TA+LIVE
Sbjct: 2234 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2263
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 110
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 18611 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 18666
Query: 111 DVCGDDDAKYTCKAVNSLGE 130
+ DD KY+ VN GE
Sbjct: 18667 NSTRDDSGKYSLTLVNPAGE 18686
Score = 32.0 bits (71), Expect = 0.22
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773
Query: 115 DDDAKYTCKAVN 126
D +Y K N
Sbjct: 24774 TDGGQYILKLSN 24785
Score = 31.6 bits (70), Expect = 0.28
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 19996 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 20054
Query: 122 CKAVNSLG--EATCTAELI 138
N G E T + +++
Sbjct: 20055 ITLKNVAGTKEGTISIKVV 20073
Score = 31.2 bits (69), Expect = 0.37
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 20840
Query: 116 DDAKYTCKAVNSLGE 130
D K+ N G+
Sbjct: 20841 DTGKFVMTIENPAGK 20855
Score = 31.2 bits (69), Expect = 0.37
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 121
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 21137
Query: 122 CKAVNSLGE 130
A N +GE
Sbjct: 21138 LTARNIVGE 21146
Score = 31.2 bits (69), Expect = 0.37
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 25796 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 25854
Query: 115 DDDAKYTCKAVNSLG 129
D +Y N G
Sbjct: 25855 RDTGQYVLTLKNVAG 25869
Score = 31.2 bits (69), Expect = 0.37
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 121
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 28372 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 28427
Query: 122 CKAVNSLGEATCT 134
N+ G + T
Sbjct: 28428 LTVENNSGSKSIT 28440
Score = 31.2 bits (69), Expect = 0.37
Identities = 26/104 (25%), Positives = 36/104 (34%), Gaps = 3/104 (2%)
Query: 39 AVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 95
A E + K + KT+ + V G G PDP + W K I + H+
Sbjct: 31015 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 31074
Query: 96 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Q+ + + V D Y A N G T EL V
Sbjct: 31075 QVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 31118
Score = 30.8 bits (68), Expect = 0.48
Identities = 12/42 (28%), Positives = 23/42 (54%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 96
++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2492
Score = 30.8 bits (68), Expect = 0.48
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYD 100
E P +K S ++V G + G P P++ W K++ I + + QI +
Sbjct: 15392 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 15451
Query: 101 E----DGNCSLIISDVCGDDDAKYTCKAVNSLG 129
E + L I +D YT A N LG
Sbjct: 15452 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 15484
Score = 30.8 bits (68), Expect = 0.48
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 55 IRDLEVVEGSAA-RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 113
+R + V+ SA R I+G P+PEV W K + + + ++ L+I +V
Sbjct: 25113 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEV---TSSFTMLVIDNVT 25169
Query: 114 GDDDAKYTCKAVNSLGEAT 132
D +Y N+ G T
Sbjct: 25170 RFDSGRYNLTLENNSGSKT 25188
Score = 30.4 bits (67), Expect = 0.63
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG------NCSLIISDVC-GD 115
GS R I+G P P+ W D ++ + + D ED N S+II C
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
KY+ A N G+ T + V
Sbjct: 15885 HTGKYSITAKNKAGQKTANCRVKV 15908
Score = 30.0 bits (66), Expect = 0.82
Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
GS + D I G P P+V +D ++ + F + + N ++ + + D +Y
Sbjct: 26491 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESVTADAGRYEI 26549
Query: 123 KAVNSLGEATCTAELIV 139
A NS G ++V
Sbjct: 26550 TAANSSGTTKAFINIVV 26566
Score = 29.6 bits (65), Expect = 1.1
Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 1/84 (1%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
+ + V G I G P P WF +RES ++ L I +
Sbjct: 29746 KTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVE-THTKVAKLTIRETTIR 29804
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
D +YT + N G + T ++I+
Sbjct: 29805 DTGEYTLELKNVTGTTSETIKVII 29828
Score = 28.1 bits (61), Expect = 3.1
Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 92
+ ++D+ V G A FDC++ Y D V W+ + + S
Sbjct: 12200 RPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPS 12238
Score = 28.1 bits (61), Expect = 3.1
Identities = 20/72 (27%), Positives = 26/72 (36%), Gaps = 1/72 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
L + G A + G P P+V WFKD+ + E I +L D
Sbjct: 16828 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK-TTPATLALEKIKAKRSDS 16886
Query: 118 AKYTCKAVNSLG 129
KY NS G
Sbjct: 16887 GKYCVVVENSTG 16898
Score = 28.1 bits (61), Expect = 3.1
Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
G + +G P P + W KD ++ES + E+ +L I + + KYT
Sbjct: 27578 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTEN-KITLSIKNAKKEHGGKYT 27635
Score = 27.7 bits (60), Expect = 4.1
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
G R ++G P P++ W K + ++R+ I D + L +V D KY
Sbjct: 19708 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVNKYDAGKYIL 19766
Query: 123 KAVNSLGEATCTAELIVETME 143
NS G+ T ++V+ ++
Sbjct: 19767 TLENSCGKKEYT--IVVKVLD 19785
Score = 26.6 bits (57), Expect = 9.1
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
++RD VV G R + G P P V W +++++ + + + S++I +
Sbjct: 16529 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAI---SSSMVIKNC 16585
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIVETME 143
Y+ A N GE T +IV+ ++
Sbjct: 16586 QRSHQGVYSLLAKNEAGERKKT--IIVDVLD 16614
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 79.3 bits (194), Expect = 1e-15
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 29 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 88
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284
Query: 89 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 76.3 bits (186), Expect = 1e-14
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 12 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 70
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918
Query: 71 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 130
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977
Query: 131 ATCTAELIVETMEEGEGE 148
+ + L V+ EE E E
Sbjct: 978 VSTSCYLAVQVSEEFEKE 995
Score = 73.6 bits (179), Expect = 6e-14
Identities = 33/91 (36%), Positives = 56/91 (61%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 70.1 bits (170), Expect = 7e-13
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 106
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 67.4 bits (163), Expect = 5e-12
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 28 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 87
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 88 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 63.2 bits (152), Expect = 9e-11
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 61.6 bits (148), Expect = 3e-10
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
II D ++T A N G ++ + L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505
Score = 59.7 bits (143), Expect = 1e-09
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
EK P F K + + ++ G A + G P P++ WF + + S ++ +D D
Sbjct: 3643 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3702
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
+ SLII +D+ +YTC A N G+ C+A L + + EG + E E
Sbjct: 3703 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3751
Score = 58.9 bits (141), Expect = 2e-09
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 101
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 102 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME-EGEGEGEEEEE 154
D L I++ +D+ YT A N++G+ + TA L +E + + G++ E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRE 3403
Score = 57.8 bits (138), Expect = 4e-09
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 107
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+IS DD +YT N GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 4e-09
Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 62 EGSAARFDCKIEGYPDP-EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
EG ++ CKIE Y +V W+ + + S ++I Y EDG L + D+ DD Y
Sbjct: 25276 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTY 25334
Query: 121 TCKAVNSLGEATCTAELIVETMEE 144
CK VN GE + AEL V+ + E
Sbjct: 25335 RCKVVNDYGEDSSYAELFVKGVRE 25358
Score = 57.8 bits (138), Expect = 4e-09
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 30 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25468 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25527
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25528 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587
Query: 147 GEGEEEEE 154
E + +EE
Sbjct: 25588 QEFKSKEE 25595
Score = 57.4 bits (137), Expect = 5e-09
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 107
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 55.8 bits (133), Expect = 1e-08
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 17 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 74
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 75 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 134
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878
Query: 135 AELIVETMEE 144
+L ++ E+
Sbjct: 1879 VKLEIQQRED 1888
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 45 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 103
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24619 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24678
Query: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
LII+ V DD Y +A N G + TA L VE
Sbjct: 24679 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24715
Score = 55.5 bits (132), Expect = 2e-08
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26887
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26888 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26923
Score = 54.3 bits (129), Expect = 4e-08
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 37 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 96
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 97 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 4e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 105
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25443
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25444 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 53.9 bits (128), Expect = 5e-08
Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
+S + + A L V P +K + I LEV G A+F C+I+ P+ WFK
Sbjct: 4511 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4566
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
+ I ES I + + SL I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4567 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4624
Score = 53.9 bits (128), Expect = 5e-08
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26536 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26595
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 148
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26596 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26645
Score = 53.1 bits (126), Expect = 9e-08
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24287
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24288 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24318
Score = 52.4 bits (124), Expect = 2e-07
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 21 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 80
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 15816 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15874
Query: 81 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 15875 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15932
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 99
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 100 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.4 bits (111), Expect = 5e-06
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 22 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 81
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 21627 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21686
Query: 82 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21687 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744
Score = 46.2 bits (108), Expect = 1e-05
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 8 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 62
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 26376 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26435
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 26436 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26486
Query: 123 K 123
+
Sbjct: 26487 E 26487
Score = 45.8 bits (107), Expect = 1e-05
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 45 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 104
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 6067 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6122
Query: 105 CSLIISDVCGDDDAKYTCK 123
L+I+ DD+A+Y+C+
Sbjct: 6123 RILVINKCLLDDEAEYSCE 6141
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 44.3 bits (103), Expect = 4e-05
Identities = 36/124 (29%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 24 EKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTI----RDLEVVEGSAARFDCKIEGYP 76
E S E S A E EEK +K + I R + V EG +ARF C +G P
Sbjct: 26224 EHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEP 26283
Query: 77 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
P V W + Q + S Q+ + + IS V D+ Y+ NS G+
Sbjct: 26284 VPTVTWLRKGQVLSTSARHQVTTTK-YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFT 26342
Query: 137 LIVE 140
L ++
Sbjct: 26343 LTIQ 26346
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 50 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 153
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 9e-05
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 110
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9821 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9879
Query: 111 DVCGDDDAKYTCKAVNSLGEAT 132
D YT AVN+LG A+
Sbjct: 9880 QSRRSDTGLYTITAVNNLGTAS 9901
Score = 43.1 bits (100), Expect = 9e-05
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12583 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12642
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12643 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683
Score = 43.1 bits (100), Expect = 9e-05
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 22 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 78
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 16212 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16268
Query: 79 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 16269 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16327
Query: 139 V 139
V
Sbjct: 16328 V 16328
Score = 42.7 bits (99), Expect = 1e-04
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 51 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 104
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4812 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4869
Query: 105 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
+I DV D +YTC E T TA+L+VE +
Sbjct: 4870 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905
Score = 42.4 bits (98), Expect = 2e-04
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16924 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16978
Query: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
+L I + DD +Y N +G+ T + E++
Sbjct: 16979 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 17013
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6217
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 153
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6218 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6265
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 104
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 27022 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27080
Query: 105 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
+LII DV D YT N G + T + + ++
Sbjct: 27081 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27118
Score = 41.2 bits (95), Expect = 4e-04
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11210 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11268
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIV 139
D +Y N+ G T L V
Sbjct: 11269 LRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 7390 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7448
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIV 139
D Y +AVN G AT E+ V
Sbjct: 7449 KRSDTGTYIIEAVNVCGRATAVVEVNV 7475
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 18005 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 18063
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I + DD KYT A NS G AT +IV
Sbjct: 18064 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096
Score = 40.4 bits (93), Expect = 6e-04
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 5982 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 6039
Query: 111 DVCGDDDAKYTCKA 124
D +D YTC A
Sbjct: 6040 DCTPEDIKTYTCDA 6053
Score = 39.7 bits (91), Expect = 0.001
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 28 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 81
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 5686 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5744
Query: 82 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5745 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5784
Score = 39.3 bits (90), Expect = 0.001
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 8071 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8130
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
D + L + D YT N LG AT + + V
Sbjct: 8131 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8171
Score = 38.9 bits (89), Expect = 0.002
Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Query: 41 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 100
A+E P ++D+ V G A+F C ++ +V W + I ES ++
Sbjct: 3481 AKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESE--RLKQS 3538
Query: 101 EDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
++GN L I +V D Y+C N GE T +A L VE E
Sbjct: 3539 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPE 3583
Score = 38.5 bits (88), Expect = 0.002
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17327 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17385
Query: 115 DDDAKYTCKAVNSLG 129
D +Y +A N G
Sbjct: 17386 IDGGQYILRASNVAG 17400
Score = 37.4 bits (85), Expect = 0.005
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 116
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8865
Query: 117 DAKYTCKAVNSLGEATCTAELIV 139
+Y A NS G A + V
Sbjct: 8866 HGRYVITATNSCGSKFAAARVEV 8888
Score = 37.4 bits (85), Expect = 0.005
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 31 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 87
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 19862 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19920
Query: 88 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 19921 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19971
Score = 37.0 bits (84), Expect = 0.007
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 110
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11608 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11664
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTA 135
+ D KY A NS G A +A
Sbjct: 11665 EAVRADHGKYIISAKNSSGHAQGSA 11689
Score = 37.0 bits (84), Expect = 0.007
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 40 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 93
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11882 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11941
Query: 94 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
++ D + S ++ D KY A N+ G A + V
Sbjct: 11942 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16703
Query: 118 AKYTCKAVNSLG 129
KYT NS G
Sbjct: 16704 GKYTLTLENSSG 16715
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 49 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 105
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20623
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCT 134
S++I D + Y K N++G A+ T
Sbjct: 20624 SILIKDADRLNSGCYELKLRNAMGSASAT 20652
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 34 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 90
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22326 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22384
Query: 91 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22385 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22432
Score = 35.8 bits (81), Expect = 0.015
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 73 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 130
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20991 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 21047
Score = 35.4 bits (80), Expect = 0.019
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 107
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 26069 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26126
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
I D DD Y N GEA+ A L V
Sbjct: 26127 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158
Score = 35.0 bits (79), Expect = 0.025
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5537 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5594
Query: 111 DVCGDDDAKYTCKA 124
+D+AKY +A
Sbjct: 5595 SAAFEDEAKYMFEA 5608
Score = 35.0 bits (79), Expect = 0.025
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 13058
Query: 118 AKYTCKAVNSLGEATCTAELIV 139
YT A NS G + T +L V
Sbjct: 13059 GDYTITAENSSGSKSATIKLKV 13080
Score = 34.7 bits (78), Expect = 0.033
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 19088 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19146
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I + +D Y NS G T +IV
Sbjct: 19147 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19179
Score = 34.3 bits (77), Expect = 0.043
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6341 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6398
Query: 115 DDDAKYTCKAVNSLGE-ATCTAELIVE 140
DD A Y N GE A LIVE
Sbjct: 6399 DDQANYNVSLTNHRGENVKSAANLIVE 6425
Score = 34.3 bits (77), Expect = 0.043
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 52 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 111
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17723 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17778
Query: 112 VCGDDDA-KYTCKAVNSLG 129
C +DA KY K NS G
Sbjct: 17779 NCDRNDAGKYILKLENSSG 17797
Score = 33.9 bits (76), Expect = 0.057
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15229
Query: 123 KAVNSLGEA 131
A N G A
Sbjct: 15230 TATNPGGFA 15238
Score = 33.9 bits (76), Expect = 0.057
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 36 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 85
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 23123 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23177
Query: 86 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 134
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 23178 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23224
Score = 33.5 bits (75), Expect = 0.074
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5271 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5328
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+V DD ++ + + E + TA+L V
Sbjct: 5329 EVTLDDISQIKAQ----VKELSSTAQLKV 5353
Score = 33.5 bits (75), Expect = 0.074
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5626 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5683
Query: 111 DVCGDDDAKYTCKAVNSLGEATCT 134
D+ DD ++ +A+ EA T
Sbjct: 5684 DLSIDDTSQIRVEAMGMSSEAKLT 5707
Score = 33.1 bits (74), Expect = 0.097
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 16 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 61
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 5311 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5370
Query: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 5371 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5427
Query: 122 CKAVNSLGEATCTAE 136
C +A T E
Sbjct: 5428 CDCGTDKTKANVTVE 5442
Score = 33.1 bits (74), Expect = 0.097
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10977
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
D Y+ N G T + +++V
Sbjct: 10978 DGGIYSLTVENPAGSKTVSVKVLV 11001
Score = 32.7 bits (73), Expect = 0.13
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 115 DDDAKYTCKAVNSLGEAT 132
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 0.13
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 121
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22757 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22814
Query: 122 CKAVNSLG 129
N+ G
Sbjct: 22815 LTVKNASG 22822
Score = 32.3 bits (72), Expect = 0.16
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 56 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 113
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6254 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6309
Query: 114 GDDDAKYTCKAVNSLGEATCTAELIV 139
D Y V +G A A L V
Sbjct: 6310 LQDMGTY----VVMVGAARAAAHLTV 6331
Score = 32.3 bits (72), Expect = 0.16
Identities = 27/111 (24%), Positives = 36/111 (32%), Gaps = 30/111 (27%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQ--------------------SIRESRHF-- 95
LEV G D I G P P + W KD+ ++E F
Sbjct: 8384 LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVL 8443
Query: 96 ------QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATCTAELI 138
ID + G L + D D Y K N G +A CT ++
Sbjct: 8444 PLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8494
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 51 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ D Y+C V T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 110
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12306 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12361
Query: 111 DVCGDDDAKYTCKAVNSLGE 130
+ DD KY+ VN GE
Sbjct: 12362 NSTRDDSGKYSLTLVNPAGE 12381
Score = 32.0 bits (71), Expect = 0.22
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468
Query: 115 DDDAKYTCKAVN 126
D +Y K N
Sbjct: 18469 TDGGQYILKLSN 18480
Score = 31.6 bits (70), Expect = 0.28
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13691 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13749
Query: 122 CKAVNSLG--EATCTAELI 138
N G E T + +++
Sbjct: 13750 ITLKNVAGTKEGTISIKVV 13768
Score = 31.2 bits (69), Expect = 0.37
Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 24 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 70
E L+ E+ ++ E+ EE VK P + D EG
Sbjct: 4397 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4456
Query: 71 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 129
I EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G
Sbjct: 4457 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4513
Query: 130 EATCTAELIV 139
+ +A+L V
Sbjct: 4514 KTATSAKLTV 4523
Score = 31.2 bits (69), Expect = 0.37
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14535
Query: 116 DDAKYTCKAVNSLGE 130
D K+ N G+
Sbjct: 14536 DTGKFVMTIENPAGK 14550
Score = 31.2 bits (69), Expect = 0.37
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 121
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14832
Query: 122 CKAVNSLGE 130
A N +GE
Sbjct: 14833 LTARNIVGE 14841
Score = 31.2 bits (69), Expect = 0.37
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19491 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19549
Query: 115 DDDAKYTCKAVNSLG 129
D +Y N G
Sbjct: 19550 RDTGQYVLTLKNVAG 19564
Score = 31.2 bits (69), Expect = 0.37
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 121
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 22067 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 22122
Query: 122 CKAVNSLGEATCT 134
N+ G + T
Sbjct: 22123 LTVENNSGSKSIT 22135
Score = 31.2 bits (69), Expect = 0.37
Identities = 26/104 (25%), Positives = 36/104 (34%), Gaps = 3/104 (2%)
Query: 39 AVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 95
A E + K + KT+ + V G G PDP + W K I + H+
Sbjct: 24710 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24769
Query: 96 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Q+ + + V D Y A N G T EL V
Sbjct: 24770 QVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24813
Score = 30.8 bits (68), Expect = 0.48
Identities = 12/42 (28%), Positives = 23/42 (54%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 96
++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 30.8 bits (68), Expect = 0.48
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYD 100
E P +K S ++V G + G P P++ W K++ I + + QI +
Sbjct: 9087 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 9146
Query: 101 E----DGNCSLIISDVCGDDDAKYTCKAVNSLG 129
E + L I +D YT A N LG
Sbjct: 9147 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 9179
Score = 30.8 bits (68), Expect = 0.48
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 55 IRDLEVVEGSAA-RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 113
+R + V+ SA R I+G P+PEV W K + + + ++ L+I +V
Sbjct: 18808 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEV---TSSFTMLVIDNVT 18864
Query: 114 GDDDAKYTCKAVNSLGEAT 132
D +Y N+ G T
Sbjct: 18865 RFDSGRYNLTLENNSGSKT 18883
Score = 30.4 bits (67), Expect = 0.63
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG------NCSLIISDVC-GD 115
GS R I+G P P+ W D ++ + + D ED N S+II C
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9579
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
KY+ A N G+ T + V
Sbjct: 9580 HTGKYSITAKNKAGQKTANCRVKV 9603
Score = 30.0 bits (66), Expect = 0.82
Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
GS + D I G P P+V +D ++ + F + + N ++ + + D +Y
Sbjct: 20186 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESVTADAGRYEI 20244
Query: 123 KAVNSLGEATCTAELIV 139
A NS G ++V
Sbjct: 20245 TAANSSGTTKAFINIVV 20261
Score = 29.6 bits (65), Expect = 1.1
Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 1/84 (1%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
+ + V G I G P P WF +RES ++ L I +
Sbjct: 23441 KTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVE-THTKVAKLTIRETTIR 23499
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
D +YT + N G + T ++I+
Sbjct: 23500 DTGEYTLELKNVTGTTSETIKVII 23523
Score = 28.1 bits (61), Expect = 3.1
Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 92
+ ++D+ V G A FDC++ Y D V W+ + + S
Sbjct: 5895 RPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPS 5933
Score = 28.1 bits (61), Expect = 3.1
Identities = 20/72 (27%), Positives = 26/72 (36%), Gaps = 1/72 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
L + G A + G P P+V WFKD+ + E I +L D
Sbjct: 10523 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK-TTPATLALEKIKAKRSDS 10581
Query: 118 AKYTCKAVNSLG 129
KY NS G
Sbjct: 10582 GKYCVVVENSTG 10593
Score = 28.1 bits (61), Expect = 3.1
Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
G + +G P P + W KD ++ES + E+ +L I + + KYT
Sbjct: 21273 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTEN-KITLSIKNAKKEHGGKYT 21330
Score = 27.7 bits (60), Expect = 4.1
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
G R ++G P P++ W K + ++R+ I D + L +V D KY
Sbjct: 13403 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVNKYDAGKYIL 13461
Query: 123 KAVNSLGEATCTAELIVETME 143
NS G+ T ++V+ ++
Sbjct: 13462 TLENSCGKKEYT--IVVKVLD 13480
Score = 26.6 bits (57), Expect = 9.1
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
++RD VV G R + G P P V W +++++ + + + S++I +
Sbjct: 10224 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAI---SSSMVIKNC 10280
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIVETME 143
Y+ A N GE T +IV+ ++
Sbjct: 10281 QRSHQGVYSLLAKNEAGERKKT--IIVDVLD 10309
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 79.3 bits (194), Expect = 1e-15
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 29 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 88
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284
Query: 89 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 76.3 bits (186), Expect = 1e-14
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 12 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 70
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918
Query: 71 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 130
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977
Query: 131 ATCTAELIVETMEEGEGE 148
+ + L V+ EE E E
Sbjct: 978 VSTSCYLAVQVSEEFEKE 995
Score = 73.6 bits (179), Expect = 6e-14
Identities = 33/91 (36%), Positives = 56/91 (61%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Score = 70.1 bits (170), Expect = 7e-13
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 106
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 69.3 bits (168), Expect = 1e-12
Identities = 34/93 (36%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCS 106
KP F + + L V G RF ++ G P PE+ WF + Q I ++ ++E G
Sbjct: 3418 KPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMAL 3477
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
++I D + +Y+CKA NS GEATC A L V
Sbjct: 3478 MLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510
Score = 67.4 bits (163), Expect = 5e-12
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 28 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 87
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 88 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 63.2 bits (152), Expect = 9e-11
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 61.6 bits (148), Expect = 3e-10
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
II D ++T A N G ++ + L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505
Score = 59.7 bits (143), Expect = 1e-09
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
EK P F K + + ++ G A + G P P++ WF + + S ++ +D D
Sbjct: 3576 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3635
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
+ SLII +D+ +YTC A N G+ C+A L + + EG + E E
Sbjct: 3636 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3684
Score = 58.9 bits (141), Expect = 2e-09
Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 101
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 102 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
D L I++ +D+ YT A N++G+ + TA L +E + E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFE 3394
Score = 57.8 bits (138), Expect = 4e-09
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 107
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+IS DD +YT N GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 4e-09
Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 62 EGSAARFDCKIEGYPDP-EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
EG ++ CKIE Y +V W+ + + S ++I Y EDG L + D+ DD Y
Sbjct: 25209 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTY 25267
Query: 121 TCKAVNSLGEATCTAELIVETMEE 144
CK VN GE + AEL V+ + E
Sbjct: 25268 RCKVVNDYGEDSSYAELFVKGVRE 25291
Score = 57.8 bits (138), Expect = 4e-09
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 30 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25401 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25460
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25461 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520
Query: 147 GEGEEEEE 154
E + +EE
Sbjct: 25521 QEFKSKEE 25528
Score = 57.4 bits (137), Expect = 5e-09
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 107
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 55.8 bits (133), Expect = 1e-08
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 17 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 74
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 75 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 134
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878
Query: 135 AELIVETMEE 144
+L ++ E+
Sbjct: 1879 VKLEIQQRED 1888
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 45 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 103
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24552 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24611
Query: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
LII+ V DD Y +A N G + TA L VE
Sbjct: 24612 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24648
Score = 55.5 bits (132), Expect = 2e-08
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26820
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26821 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26856
Score = 54.3 bits (129), Expect = 4e-08
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 37 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 96
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 97 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 4e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 105
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25376
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25377 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 53.9 bits (128), Expect = 5e-08
Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
+S + + A L V P +K + I LEV G A+F C+I+ P+ WFK
Sbjct: 4444 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4499
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
+ I ES I + + SL I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4500 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4557
Score = 53.9 bits (128), Expect = 5e-08
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26469 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26528
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 148
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26529 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26578
Score = 53.1 bits (126), Expect = 9e-08
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24220
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24221 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24251
Score = 52.4 bits (124), Expect = 2e-07
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 21 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 80
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 15749 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15807
Query: 81 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 15808 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15865
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 99
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 100 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.4 bits (111), Expect = 5e-06
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 22 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 81
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 21560 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21619
Query: 82 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21620 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677
Score = 46.2 bits (108), Expect = 1e-05
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 8 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 62
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 26309 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26368
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 26369 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26419
Query: 123 K 123
+
Sbjct: 26420 E 26420
Score = 45.8 bits (107), Expect = 1e-05
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 45 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 104
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 6000 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6055
Query: 105 CSLIISDVCGDDDAKYTCK 123
L+I+ DD+A+Y+C+
Sbjct: 6056 RILVINKCLLDDEAEYSCE 6074
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 44.3 bits (103), Expect = 4e-05
Identities = 36/124 (29%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 24 EKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTI----RDLEVVEGSAARFDCKIEGYP 76
E S E S A E EEK +K + I R + V EG +ARF C +G P
Sbjct: 26157 EHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEP 26216
Query: 77 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
P V W + Q + S Q+ + + IS V D+ Y+ NS G+
Sbjct: 26217 VPTVTWLRKGQVLSTSARHQVTTTK-YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFT 26275
Query: 137 LIVE 140
L ++
Sbjct: 26276 LTIQ 26279
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 50 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 153
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 9e-05
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 110
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9754 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9812
Query: 111 DVCGDDDAKYTCKAVNSLGEAT 132
D YT AVN+LG A+
Sbjct: 9813 QSRRSDTGLYTITAVNNLGTAS 9834
Score = 43.1 bits (100), Expect = 9e-05
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12516 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12575
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12576 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616
Score = 43.1 bits (100), Expect = 9e-05
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 22 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 78
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 16145 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16201
Query: 79 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 16202 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16260
Query: 139 V 139
V
Sbjct: 16261 V 16261
Score = 42.7 bits (99), Expect = 1e-04
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 51 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 104
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4745 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4802
Query: 105 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
+I DV D +YTC E T TA+L+VE +
Sbjct: 4803 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838
Score = 42.4 bits (98), Expect = 2e-04
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16857 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16911
Query: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
+L I + DD +Y N +G+ T + E++
Sbjct: 16912 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16946
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6150
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 153
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6151 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6198
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 104
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 26955 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27013
Query: 105 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
+LII DV D YT N G + T + + ++
Sbjct: 27014 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27051
Score = 41.2 bits (95), Expect = 4e-04
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11143 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11201
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIV 139
D +Y N+ G T L V
Sbjct: 11202 LRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 7323 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7381
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIV 139
D Y +AVN G AT E+ V
Sbjct: 7382 KRSDTGTYIIEAVNVCGRATAVVEVNV 7408
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 17938 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17996
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I + DD KYT A NS G AT +IV
Sbjct: 17997 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029
Score = 40.4 bits (93), Expect = 6e-04
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 5915 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 5972
Query: 111 DVCGDDDAKYTCKA 124
D +D YTC A
Sbjct: 5973 DCTPEDIKTYTCDA 5986
Score = 39.7 bits (91), Expect = 0.001
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 28 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 81
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 5619 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5677
Query: 82 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5678 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5717
Score = 39.3 bits (90), Expect = 0.001
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 8004 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8063
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
D + L + D YT N LG AT + + V
Sbjct: 8064 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8104
Score = 38.5 bits (88), Expect = 0.002
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17260 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17318
Query: 115 DDDAKYTCKAVNSLG 129
D +Y +A N G
Sbjct: 17319 IDGGQYILRASNVAG 17333
Score = 37.4 bits (85), Expect = 0.005
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 116
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8798
Query: 117 DAKYTCKAVNSLGEATCTAELIV 139
+Y A NS G A + V
Sbjct: 8799 HGRYVITATNSCGSKFAAARVEV 8821
Score = 37.4 bits (85), Expect = 0.005
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 31 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 87
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 19795 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19853
Query: 88 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 19854 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19904
Score = 37.0 bits (84), Expect = 0.007
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 110
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11541 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11597
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTA 135
+ D KY A NS G A +A
Sbjct: 11598 EAVRADHGKYIISAKNSSGHAQGSA 11622
Score = 37.0 bits (84), Expect = 0.007
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 40 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 93
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11815 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11874
Query: 94 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
++ D + S ++ D KY A N+ G A + V
Sbjct: 11875 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16636
Query: 118 AKYTCKAVNSLG 129
KYT NS G
Sbjct: 16637 GKYTLTLENSSG 16648
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 49 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 105
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20556
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCT 134
S++I D + Y K N++G A+ T
Sbjct: 20557 SILIKDADRLNSGCYELKLRNAMGSASAT 20585
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 34 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 90
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22259 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22317
Query: 91 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22318 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22365
Score = 35.8 bits (81), Expect = 0.015
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 73 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 130
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20924 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20980
Score = 35.4 bits (80), Expect = 0.019
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 107
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 26002 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26059
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
I D DD Y N GEA+ A L V
Sbjct: 26060 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091
Score = 35.0 bits (79), Expect = 0.025
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5470 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5527
Query: 111 DVCGDDDAKYTCKA 124
+D+AKY +A
Sbjct: 5528 SAAFEDEAKYMFEA 5541
Score = 35.0 bits (79), Expect = 0.025
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12991
Query: 118 AKYTCKAVNSLGEATCTAELIV 139
YT A NS G + T +L V
Sbjct: 12992 GDYTITAENSSGSKSATIKLKV 13013
Score = 34.7 bits (78), Expect = 0.033
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 19021 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19079
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I + +D Y NS G T +IV
Sbjct: 19080 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19112
Score = 34.3 bits (77), Expect = 0.043
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6274 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6331
Query: 115 DDDAKYTCKAVNSLGE-ATCTAELIVE 140
DD A Y N GE A LIVE
Sbjct: 6332 DDQANYNVSLTNHRGENVKSAANLIVE 6358
Score = 34.3 bits (77), Expect = 0.043
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 52 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 111
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17656 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17711
Query: 112 VCGDDDA-KYTCKAVNSLG 129
C +DA KY K NS G
Sbjct: 17712 NCDRNDAGKYILKLENSSG 17730
Score = 33.9 bits (76), Expect = 0.057
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15162
Query: 123 KAVNSLGEA 131
A N G A
Sbjct: 15163 TATNPGGFA 15171
Score = 33.9 bits (76), Expect = 0.057
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 36 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 85
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 23056 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23110
Query: 86 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 134
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 23111 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23157
Score = 33.5 bits (75), Expect = 0.074
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5204 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5261
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+V DD ++ + + E + TA+L V
Sbjct: 5262 EVTLDDISQIKAQ----VKELSSTAQLKV 5286
Score = 33.5 bits (75), Expect = 0.074
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5559 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5616
Query: 111 DVCGDDDAKYTCKAVNSLGEATCT 134
D+ DD ++ +A+ EA T
Sbjct: 5617 DLSIDDTSQIRVEAMGMSSEAKLT 5640
Score = 33.1 bits (74), Expect = 0.097
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 16 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 61
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 5244 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5303
Query: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 5304 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5360
Query: 122 CKAVNSLGEATCTAE 136
C +A T E
Sbjct: 5361 CDCGTDKTKANVTVE 5375
Score = 33.1 bits (74), Expect = 0.097
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10910
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
D Y+ N G T + +++V
Sbjct: 10911 DGGIYSLTVENPAGSKTVSVKVLV 10934
Score = 32.7 bits (73), Expect = 0.13
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 115 DDDAKYTCKAVNSLGEAT 132
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 0.13
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 121
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22690 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22747
Query: 122 CKAVNSLG 129
N+ G
Sbjct: 22748 LTVKNASG 22755
Score = 32.3 bits (72), Expect = 0.16
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 56 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 113
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6187 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6242
Query: 114 GDDDAKYTCKAVNSLGEATCTAELIV 139
D Y V +G A A L V
Sbjct: 6243 LQDMGTY----VVMVGAARAAAHLTV 6264
Score = 32.3 bits (72), Expect = 0.16
Identities = 27/111 (24%), Positives = 36/111 (32%), Gaps = 30/111 (27%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQ--------------------SIRESRHF-- 95
LEV G D I G P P + W KD+ ++E F
Sbjct: 8317 LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVL 8376
Query: 96 ------QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATCTAELI 138
ID + G L + D D Y K N G +A CT ++
Sbjct: 8377 PLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8427
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 51 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ D Y+C V T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 110
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12239 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12294
Query: 111 DVCGDDDAKYTCKAVNSLGE 130
+ DD KY+ VN GE
Sbjct: 12295 NSTRDDSGKYSLTLVNPAGE 12314
Score = 32.0 bits (71), Expect = 0.22
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401
Query: 115 DDDAKYTCKAVN 126
D +Y K N
Sbjct: 18402 TDGGQYILKLSN 18413
Score = 31.6 bits (70), Expect = 0.28
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13624 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13682
Query: 122 CKAVNSLG--EATCTAELI 138
N G E T + +++
Sbjct: 13683 ITLKNVAGTKEGTISIKVV 13701
Score = 31.2 bits (69), Expect = 0.37
Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 24 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 70
E L+ E+ ++ E+ EE VK P + D EG
Sbjct: 4330 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4389
Query: 71 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 129
I EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G
Sbjct: 4390 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4446
Query: 130 EATCTAELIV 139
+ +A+L V
Sbjct: 4447 KTATSAKLTV 4456
Score = 31.2 bits (69), Expect = 0.37
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14468
Query: 116 DDAKYTCKAVNSLGE 130
D K+ N G+
Sbjct: 14469 DTGKFVMTIENPAGK 14483
Score = 31.2 bits (69), Expect = 0.37
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 121
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14765
Query: 122 CKAVNSLGE 130
A N +GE
Sbjct: 14766 LTARNIVGE 14774
Score = 31.2 bits (69), Expect = 0.37
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19424 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19482
Query: 115 DDDAKYTCKAVNSLG 129
D +Y N G
Sbjct: 19483 RDTGQYVLTLKNVAG 19497
Score = 31.2 bits (69), Expect = 0.37
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 121
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 22000 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 22055
Query: 122 CKAVNSLGEATCT 134
N+ G + T
Sbjct: 22056 LTVENNSGSKSIT 22068
Score = 31.2 bits (69), Expect = 0.37
Identities = 26/104 (25%), Positives = 36/104 (34%), Gaps = 3/104 (2%)
Query: 39 AVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 95
A E + K + KT+ + V G G PDP + W K I + H+
Sbjct: 24643 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24702
Query: 96 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Q+ + + V D Y A N G T EL V
Sbjct: 24703 QVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24746
Score = 30.8 bits (68), Expect = 0.48
Identities = 12/42 (28%), Positives = 23/42 (54%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 96
++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 30.8 bits (68), Expect = 0.48
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYD 100
E P +K S ++V G + G P P++ W K++ I + + QI +
Sbjct: 9020 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 9079
Query: 101 E----DGNCSLIISDVCGDDDAKYTCKAVNSLG 129
E + L I +D YT A N LG
Sbjct: 9080 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 9112
Score = 30.8 bits (68), Expect = 0.48
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 55 IRDLEVVEGSAA-RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 113
+R + V+ SA R I+G P+PEV W K + + + ++ L+I +V
Sbjct: 18741 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEV---TSSFTMLVIDNVT 18797
Query: 114 GDDDAKYTCKAVNSLGEAT 132
D +Y N+ G T
Sbjct: 18798 RFDSGRYNLTLENNSGSKT 18816
Score = 30.4 bits (67), Expect = 0.63
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG------NCSLIISDVC-GD 115
GS R I+G P P+ W D ++ + + D ED N S+II C
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9512
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
KY+ A N G+ T + V
Sbjct: 9513 HTGKYSITAKNKAGQKTANCRVKV 9536
Score = 30.0 bits (66), Expect = 0.82
Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
GS + D I G P P+V +D ++ + F + + N ++ + + D +Y
Sbjct: 20119 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESVTADAGRYEI 20177
Query: 123 KAVNSLGEATCTAELIV 139
A NS G ++V
Sbjct: 20178 TAANSSGTTKAFINIVV 20194
Score = 29.6 bits (65), Expect = 1.1
Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 1/84 (1%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
+ + V G I G P P WF +RES ++ L I +
Sbjct: 23374 KTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVE-THTKVAKLTIRETTIR 23432
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
D +YT + N G + T ++I+
Sbjct: 23433 DTGEYTLELKNVTGTTSETIKVII 23456
Score = 28.1 bits (61), Expect = 3.1
Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 92
+ ++D+ V G A FDC++ Y D V W+ + + S
Sbjct: 5828 RPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPS 5866
Score = 28.1 bits (61), Expect = 3.1
Identities = 20/72 (27%), Positives = 26/72 (36%), Gaps = 1/72 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
L + G A + G P P+V WFKD+ + E I +L D
Sbjct: 10456 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK-TTPATLALEKIKAKRSDS 10514
Query: 118 AKYTCKAVNSLG 129
KY NS G
Sbjct: 10515 GKYCVVVENSTG 10526
Score = 28.1 bits (61), Expect = 3.1
Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
G + +G P P + W KD ++ES + E+ +L I + + KYT
Sbjct: 21206 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTEN-KITLSIKNAKKEHGGKYT 21263
Score = 27.7 bits (60), Expect = 4.1
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
G R ++G P P++ W K + ++R+ I D + L +V D KY
Sbjct: 13336 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVNKYDAGKYIL 13394
Query: 123 KAVNSLGEATCTAELIVETME 143
NS G+ T ++V+ ++
Sbjct: 13395 TLENSCGKKEYT--IVVKVLD 13413
Score = 26.6 bits (57), Expect = 9.1
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
++RD VV G R + G P P V W +++++ + + + S++I +
Sbjct: 10157 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAI---SSSMVIKNC 10213
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIVETME 143
Y+ A N GE T +IV+ ++
Sbjct: 10214 QRSHQGVYSLLAKNEAGERKKT--IIVDVLD 10242
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 79.3 bits (194), Expect = 1e-15
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 29 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 88
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284
Query: 89 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 76.3 bits (186), Expect = 1e-14
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 12 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 70
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918
Query: 71 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 130
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977
Query: 131 ATCTAELIVETMEEGEGE 148
+ + L V+ EE E E
Sbjct: 978 VSTSCYLAVQVSEEFEKE 995
Score = 73.6 bits (179), Expect = 6e-14
Identities = 33/91 (36%), Positives = 56/91 (61%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 70.1 bits (170), Expect = 7e-13
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 106
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 67.4 bits (163), Expect = 5e-12
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 28 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 87
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 88 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 63.2 bits (152), Expect = 9e-11
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 61.6 bits (148), Expect = 3e-10
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
II D ++T A N G ++ + L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505
Score = 60.8 bits (146), Expect = 4e-10
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 101
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 102 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 153
D L I++ +D+ YT A N++G+ + TA L +E E E E+E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3401
Score = 59.7 bits (143), Expect = 1e-09
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
EK P F K + + ++ G A + G P P++ WF + + S ++ +D D
Sbjct: 3451 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3510
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
+ SLII +D+ +YTC A N G+ C+A L + + EG + E E
Sbjct: 3511 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3559
Score = 57.8 bits (138), Expect = 4e-09
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 107
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+IS DD +YT N GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 4e-09
Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 62 EGSAARFDCKIEGYPDP-EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
EG ++ CKIE Y +V W+ + + S ++I Y EDG L + D+ DD Y
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTY 25142
Query: 121 TCKAVNSLGEATCTAELIVETMEE 144
CK VN GE + AEL V+ + E
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVRE 25166
Score = 57.8 bits (138), Expect = 4e-09
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 30 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25276 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25335
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25336 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395
Query: 147 GEGEEEEE 154
E + +EE
Sbjct: 25396 QEFKSKEE 25403
Score = 57.4 bits (137), Expect = 5e-09
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 107
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 55.8 bits (133), Expect = 1e-08
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 17 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 74
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 75 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 134
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878
Query: 135 AELIVETMEE 144
+L ++ E+
Sbjct: 1879 VKLEIQQRED 1888
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 45 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 103
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24427 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24486
Query: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
LII+ V DD Y +A N G + TA L VE
Sbjct: 24487 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523
Score = 55.5 bits (132), Expect = 2e-08
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26695
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26696 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26731
Score = 54.3 bits (129), Expect = 4e-08
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 37 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 96
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 97 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 4e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 105
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25251
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 53.9 bits (128), Expect = 5e-08
Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
+S + + A L V P +K + I LEV G A+F C+I+ P+ WFK
Sbjct: 4319 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4374
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
+ I ES I + + SL I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4375 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4432
Score = 53.9 bits (128), Expect = 5e-08
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26344 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26403
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 148
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26404 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26453
Score = 53.1 bits (126), Expect = 9e-08
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24096 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24126
Score = 52.4 bits (124), Expect = 2e-07
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 21 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 80
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 15624 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15682
Query: 81 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 15683 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15740
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 99
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 100 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.4 bits (111), Expect = 5e-06
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 22 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 81
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 21435 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21494
Query: 82 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21495 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552
Score = 46.2 bits (108), Expect = 1e-05
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 8 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 62
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 26184 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26243
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 26244 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26294
Query: 123 K 123
+
Sbjct: 26295 E 26295
Score = 45.8 bits (107), Expect = 1e-05
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 45 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 104
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 5875 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 5930
Query: 105 CSLIISDVCGDDDAKYTCK 123
L+I+ DD+A+Y+C+
Sbjct: 5931 RILVINKCLLDDEAEYSCE 5949
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 44.3 bits (103), Expect = 4e-05
Identities = 36/124 (29%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 24 EKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTI----RDLEVVEGSAARFDCKIEGYP 76
E S E S A E EEK +K + I R + V EG +ARF C +G P
Sbjct: 26032 EHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEP 26091
Query: 77 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
P V W + Q + S Q+ + + IS V D+ Y+ NS G+
Sbjct: 26092 VPTVTWLRKGQVLSTSARHQVTTTK-YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFT 26150
Query: 137 LIVE 140
L ++
Sbjct: 26151 LTIQ 26154
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 50 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 153
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 9e-05
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 110
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9629 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9687
Query: 111 DVCGDDDAKYTCKAVNSLGEAT 132
D YT AVN+LG A+
Sbjct: 9688 QSRRSDTGLYTITAVNNLGTAS 9709
Score = 43.1 bits (100), Expect = 9e-05
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12391 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12450
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12451 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491
Score = 43.1 bits (100), Expect = 9e-05
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 22 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 78
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 16020 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16076
Query: 79 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 16077 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16135
Query: 139 V 139
V
Sbjct: 16136 V 16136
Score = 42.7 bits (99), Expect = 1e-04
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 51 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 104
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4620 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4677
Query: 105 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
+I DV D +YTC E T TA+L+VE +
Sbjct: 4678 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713
Score = 42.4 bits (98), Expect = 2e-04
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16732 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16786
Query: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
+L I + DD +Y N +G+ T + E++
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16821
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6025
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 153
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6026 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6073
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 104
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 26888
Query: 105 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
+LII DV D YT N G + T + + ++
Sbjct: 26889 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 26926
Score = 41.2 bits (95), Expect = 4e-04
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11018 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11076
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIV 139
D +Y N+ G T L V
Sbjct: 11077 LRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 7198 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7256
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIV 139
D Y +AVN G AT E+ V
Sbjct: 7257 KRSDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17871
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I + DD KYT A NS G AT +IV
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 40.4 bits (93), Expect = 6e-04
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 5847
Query: 111 DVCGDDDAKYTCKA 124
D +D YTC A
Sbjct: 5848 DCTPEDIKTYTCDA 5861
Score = 39.7 bits (91), Expect = 0.001
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 28 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 81
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 5494 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5552
Query: 82 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5553 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5592
Score = 39.3 bits (90), Expect = 0.001
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 38 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 97
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 7879 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 7938
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
D + L + D YT N LG AT + + V
Sbjct: 7939 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 38.5 bits (88), Expect = 0.002
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17135 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17193
Query: 115 DDDAKYTCKAVNSLG 129
D +Y +A N G
Sbjct: 17194 IDGGQYILRASNVAG 17208
Score = 37.4 bits (85), Expect = 0.005
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 116
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8673
Query: 117 DAKYTCKAVNSLGEATCTAELIV 139
+Y A NS G A + V
Sbjct: 8674 HGRYVITATNSCGSKFAAARVEV 8696
Score = 37.4 bits (85), Expect = 0.005
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 31 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 87
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 19670 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19728
Query: 88 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 19729 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19779
Score = 37.0 bits (84), Expect = 0.007
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 110
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11416 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11472
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTA 135
+ D KY A NS G A +A
Sbjct: 11473 EAVRADHGKYIISAKNSSGHAQGSA 11497
Score = 37.0 bits (84), Expect = 0.007
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 40 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 93
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11690 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11749
Query: 94 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
++ D + S ++ D KY A N+ G A + V
Sbjct: 11750 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16511
Query: 118 AKYTCKAVNSLG 129
KYT NS G
Sbjct: 16512 GKYTLTLENSSG 16523
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 49 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 105
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20431
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCT 134
S++I D + Y K N++G A+ T
Sbjct: 20432 SILIKDADRLNSGCYELKLRNAMGSASAT 20460
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 34 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 90
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22134 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22192
Query: 91 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22193 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22240
Score = 35.8 bits (81), Expect = 0.015
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 73 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 130
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20855
Score = 35.4 bits (80), Expect = 0.019
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 107
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 25934
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
I D DD Y N GEA+ A L V
Sbjct: 25935 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 35.0 bits (79), Expect = 0.025
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5345 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5402
Query: 111 DVCGDDDAKYTCKA 124
+D+AKY +A
Sbjct: 5403 SAAFEDEAKYMFEA 5416
Score = 35.0 bits (79), Expect = 0.025
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12866
Query: 118 AKYTCKAVNSLGEATCTAELIV 139
YT A NS G + T +L V
Sbjct: 12867 GDYTITAENSSGSKSATIKLKV 12888
Score = 34.7 bits (78), Expect = 0.033
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 18896 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 18954
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
L I + +D Y NS G T +IV
Sbjct: 18955 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 18987
Score = 34.3 bits (77), Expect = 0.043
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6149 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6206
Query: 115 DDDAKYTCKAVNSLGE-ATCTAELIVE 140
DD A Y N GE A LIVE
Sbjct: 6207 DDQANYNVSLTNHRGENVKSAANLIVE 6233
Score = 34.3 bits (77), Expect = 0.043
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 52 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 111
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17531 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17586
Query: 112 VCGDDDA-KYTCKAVNSLG 129
C +DA KY K NS G
Sbjct: 17587 NCDRNDAGKYILKLENSSG 17605
Score = 33.9 bits (76), Expect = 0.057
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15037
Query: 123 KAVNSLGEA 131
A N G A
Sbjct: 15038 TATNPGGFA 15046
Score = 33.9 bits (76), Expect = 0.057
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 36 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 85
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 22931 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 22985
Query: 86 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 134
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 22986 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23032
Score = 33.5 bits (75), Expect = 0.074
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5079 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5136
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+V DD ++ + + E + TA+L V
Sbjct: 5137 EVTLDDISQIKAQ----VKELSSTAQLKV 5161
Score = 33.5 bits (75), Expect = 0.074
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5434 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5491
Query: 111 DVCGDDDAKYTCKAVNSLGEATCT 134
D+ DD ++ +A+ EA T
Sbjct: 5492 DLSIDDTSQIRVEAMGMSSEAKLT 5515
Score = 33.1 bits (74), Expect = 0.097
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 16 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 61
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 5119 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5178
Query: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 5179 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5235
Query: 122 CKAVNSLGEATCTAE 136
C +A T E
Sbjct: 5236 CDCGTDKTKANVTVE 5250
Score = 33.1 bits (74), Expect = 0.097
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10785
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
D Y+ N G T + +++V
Sbjct: 10786 DGGIYSLTVENPAGSKTVSVKVLV 10809
Score = 32.7 bits (73), Expect = 0.13
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 115 DDDAKYTCKAVNSLGEAT 132
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 0.13
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 121
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22622
Query: 122 CKAVNSLG 129
N+ G
Sbjct: 22623 LTVKNASG 22630
Score = 32.3 bits (72), Expect = 0.16
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 56 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 113
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6062 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6117
Query: 114 GDDDAKYTCKAVNSLGEATCTAELIV 139
D Y V +G A A L V
Sbjct: 6118 LQDMGTY----VVMVGAARAAAHLTV 6139
Score = 32.3 bits (72), Expect = 0.16
Identities = 27/111 (24%), Positives = 36/111 (32%), Gaps = 30/111 (27%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQ--------------------SIRESRHF-- 95
LEV G D I G P P + W KD+ ++E F
Sbjct: 8192 LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVL 8251
Query: 96 ------QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATCTAELI 138
ID + G L + D D Y K N G +A CT ++
Sbjct: 8252 PLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8302
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 51 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ D Y+C V T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 110
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12114 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12169
Query: 111 DVCGDDDAKYTCKAVNSLGE 130
+ DD KY+ VN GE
Sbjct: 12170 NSTRDDSGKYSLTLVNPAGE 12189
Score = 32.0 bits (71), Expect = 0.22
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276
Query: 115 DDDAKYTCKAVN 126
D +Y K N
Sbjct: 18277 TDGGQYILKLSN 18288
Score = 31.6 bits (70), Expect = 0.28
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13557
Query: 122 CKAVNSLG--EATCTAELI 138
N G E T + +++
Sbjct: 13558 ITLKNVAGTKEGTISIKVV 13576
Score = 31.2 bits (69), Expect = 0.37
Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 24 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 70
E L+ E+ ++ E+ EE VK P + D EG
Sbjct: 4205 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4264
Query: 71 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 129
I EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G
Sbjct: 4265 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4321
Query: 130 EATCTAELIV 139
+ +A+L V
Sbjct: 4322 KTATSAKLTV 4331
Score = 31.2 bits (69), Expect = 0.37
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14343
Query: 116 DDAKYTCKAVNSLGE 130
D K+ N G+
Sbjct: 14344 DTGKFVMTIENPAGK 14358
Score = 31.2 bits (69), Expect = 0.37
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 121
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14640
Query: 122 CKAVNSLGE 130
A N +GE
Sbjct: 14641 LTARNIVGE 14649
Score = 31.2 bits (69), Expect = 0.37
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 56 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19299 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19357
Query: 115 DDDAKYTCKAVNSLG 129
D +Y N G
Sbjct: 19358 RDTGQYVLTLKNVAG 19372
Score = 31.2 bits (69), Expect = 0.37
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 121
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 21875 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 21930
Query: 122 CKAVNSLGEATCT 134
N+ G + T
Sbjct: 21931 LTVENNSGSKSIT 21943
Score = 31.2 bits (69), Expect = 0.37
Identities = 26/104 (25%), Positives = 36/104 (34%), Gaps = 3/104 (2%)
Query: 39 AVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 95
A E + K + KT+ + V G G PDP + W K I + H+
Sbjct: 24518 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24577
Query: 96 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Q+ + + V D Y A N G T EL V
Sbjct: 24578 QVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24621
Score = 30.8 bits (68), Expect = 0.48
Identities = 12/42 (28%), Positives = 23/42 (54%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 96
++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 30.8 bits (68), Expect = 0.48
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYD 100
E P +K S ++V G + G P P++ W K++ I + + QI +
Sbjct: 8895 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 8954
Query: 101 E----DGNCSLIISDVCGDDDAKYTCKAVNSLG 129
E + L I +D YT A N LG
Sbjct: 8955 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 8987
Score = 30.8 bits (68), Expect = 0.48
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 55 IRDLEVVEGSAA-RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 113
+R + V+ SA R I+G P+PEV W K + + + ++ L+I +V
Sbjct: 18616 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEV---TSSFTMLVIDNVT 18672
Query: 114 GDDDAKYTCKAVNSLGEAT 132
D +Y N+ G T
Sbjct: 18673 RFDSGRYNLTLENNSGSKT 18691
Score = 30.4 bits (67), Expect = 0.63
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG------NCSLIISDVC-GD 115
GS R I+G P P+ W D ++ + + D ED N S+II C
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9387
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
KY+ A N G+ T + V
Sbjct: 9388 HTGKYSITAKNKAGQKTANCRVKV 9411
Score = 30.0 bits (66), Expect = 0.82
Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
GS + D I G P P+V +D ++ + F + + N ++ + + D +Y
Sbjct: 19994 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESVTADAGRYEI 20052
Query: 123 KAVNSLGEATCTAELIV 139
A NS G ++V
Sbjct: 20053 TAANSSGTTKAFINIVV 20069
Score = 29.6 bits (65), Expect = 1.1
Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 1/84 (1%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 115
+ + V G I G P P WF +RES ++ L I +
Sbjct: 23249 KTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVE-THTKVAKLTIRETTIR 23307
Query: 116 DDAKYTCKAVNSLGEATCTAELIV 139
D +YT + N G + T ++I+
Sbjct: 23308 DTGEYTLELKNVTGTTSETIKVII 23331
Score = 28.1 bits (61), Expect = 3.1
Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 92
+ ++D+ V G A FDC++ Y D V W+ + + S
Sbjct: 5703 RPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPS 5741
Score = 28.1 bits (61), Expect = 3.1
Identities = 20/72 (27%), Positives = 26/72 (36%), Gaps = 1/72 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
L + G A + G P P+V WFKD+ + E I +L D
Sbjct: 10331 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK-TTPATLALEKIKAKRSDS 10389
Query: 118 AKYTCKAVNSLG 129
KY NS G
Sbjct: 10390 GKYCVVVENSTG 10401
Score = 28.1 bits (61), Expect = 3.1
Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
G + +G P P + W KD ++ES + E+ +L I + + KYT
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTEN-KITLSIKNAKKEHGGKYT 21138
Score = 27.7 bits (60), Expect = 4.1
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
G R ++G P P++ W K + ++R+ I D + L +V D KY
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVNKYDAGKYIL 13269
Query: 123 KAVNSLGEATCTAELIVETME 143
NS G+ T ++V+ ++
Sbjct: 13270 TLENSCGKKEYT--IVVKVLD 13288
Score = 26.6 bits (57), Expect = 9.1
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 54 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
++RD VV G R + G P P V W +++++ + + + S++I +
Sbjct: 10032 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAI---SSSMVIKNC 10088
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIVETME 143
Y+ A N GE T +IV+ ++
Sbjct: 10089 QRSHQGVYSLLAKNEAGERKKT--IIVDVLD 10117
>gi|93102361 palladin [Homo sapiens]
Length = 1106
Score = 77.0 bits (188), Expect = 6e-15
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHFQIDYDEDGNCSL 107
P+F ++ ++ EG F C++ G P P++ WFKD + I +S H+ I D DG CSL
Sbjct: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
+ DDD YT A N G +CT L+V+ + +
Sbjct: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQ 873
Score = 69.3 bits (168), Expect = 1e-12
Identities = 44/141 (31%), Positives = 66/141 (46%), Gaps = 2/141 (1%)
Query: 3 MISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVE 62
M+ ++ R S SP+ + + S S E + E +P+F + DL V E
Sbjct: 867 MVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER--FFRPHFLQAPGDLTVQE 924
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 122
G R DCK+ G P P++ W D + +R ++ E+G SLII V D YTC
Sbjct: 925 GKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTC 984
Query: 123 KAVNSLGEATCTAELIVETME 143
A N G+ + + EL+V E
Sbjct: 985 IATNRAGQNSFSLELVVAAKE 1005
Score = 67.8 bits (164), Expect = 4e-12
Identities = 33/102 (32%), Positives = 52/102 (50%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F + +R EV EGS +C++ G P P V WF + + + + QI + +LI
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 150
I++ DD +YTC A N G T +AE+ +E + + E
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372
Score = 63.9 bits (154), Expect = 5e-11
Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 7/98 (7%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-------DYDE 101
P F+K +++ V EG +C++ G P +V WF+ I++S F+I +
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
Query: 102 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ C+L+I++ +D +TC A N G AT TA+L+V
Sbjct: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Score = 60.8 bits (146), Expect = 4e-10
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 40 VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR-HFQID 98
VA ++ H P F + +++ V +G R +C++ G P P++ W K+++S+ S +
Sbjct: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
Query: 99 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
D G L+I +D YT A N G +CTA L V
Sbjct: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 71.2 bits (173), Expect = 3e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F +++ EV +G FDC + G P P V WFKD + + E H+ I+ D+ G LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I+ V D Y C A NS+G ++ AEL V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217
Score = 68.6 bits (166), Expect = 2e-12
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 101
E K P FS T D E G A R +C + D W KD + + RH ID
Sbjct: 4891 EMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG 4950
Query: 102 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 153
DG CSL+I+ + D YTC+ N G+ T +A ++V E+ E GE ++
Sbjct: 4951 DGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDD 5005
Score = 63.5 bits (153), Expect = 7e-11
Identities = 25/92 (27%), Positives = 49/92 (53%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F + + D G + C++ G P P + W+KD ++++ H + D DG+C+LI
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ + G D +Y C A ++ G + +++V+
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ 6105
Score = 62.0 bits (149), Expect = 2e-10
Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ-IDYDEDGNC 105
V P F +R VEG A+F C IEG P P++ W+KD + FQ + G
Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 141
L+I +D Y C+ VN LG A +AEL +++
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 59.7 bits (143), Expect = 1e-09
Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Query: 49 PYFSKTIRDLEVVEGSA-ARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
P + +RDL+V G+ A+F K++GYP P + WFKD Q + S H ++ D+ +L
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTL 5318
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
I V +D +Y N++G A +A L+V +E E
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE 5357
Score = 53.9 bits (128), Expect = 5e-08
Identities = 35/99 (35%), Positives = 43/99 (43%), Gaps = 2/99 (2%)
Query: 41 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 100
AE P P S R V EG AR C + G P PE VW KD Q + E R + D
Sbjct: 232 AEGAPASPP--STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYED 289
Query: 101 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
N L I D YTC A N +G+ + ++V
Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 52.4 bits (124), Expect = 2e-07
Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
Query: 39 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 98
A AE+ PH F + V EGS A F C++ G P P V W KD + + E ++
Sbjct: 104 ACAEQAPH----FLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVR 159
Query: 99 YDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 141
+E G S L I D Y +A N LG A+ A L+V++
Sbjct: 160 VEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203
Score = 52.0 bits (123), Expect = 2e-07
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F + V G A C+I G P P+V W KD Q + F++ D D L
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLT 68
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I D+ D +Y C+A N++GEA L V+
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100
Score = 48.1 bits (113), Expect = 3e-06
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F K ++DLEV E +A F C++ P E WFK++ + S + I+ +E L +
Sbjct: 335 FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIE-EEGTERRLTVR 392
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+V DDDA Y C+ + AEL V+
Sbjct: 393 NVSADDDAVYICETPEG---SRTVAELAVQ 419
Score = 47.8 bits (112), Expect = 4e-06
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 42 EEKPH-------VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH 94
EEKP V P + +V +GS+ F K+EG P P V W +++ E
Sbjct: 5357 EEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---ERGV 5413
Query: 95 FQIDYDEDGNC--------SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
I D G SL++ DV YTC A N+ G+A C+A L V + + E
Sbjct: 5414 LWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473
Query: 147 GEGEEEE 153
+ + +E
Sbjct: 5474 EQEKVKE 5480
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 46 HVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 104
H +P F + ++DLEV+EG AA C + P V W + +R + + E
Sbjct: 3181 HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSL-RQEGAM 3238
Query: 105 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
L++ ++ D +Y+C S G+ T +A L V +
Sbjct: 3239 LELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTAL 3272
Score = 37.0 bits (84), Expect = 0.007
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
+P F + ++ L+ EGS A C++ P VVW K ++ + + + L
Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRL-QGCTAEL 3946
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCT 134
++ D+ +D +YTC + AT T
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLT 3973
Score = 36.6 bits (83), Expect = 0.009
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
+ +RD +E +C++ +V WFK Q ++ +++ D LIISDV
Sbjct: 2294 RPLRDKIAMEKHRGVLECQVSR-ASAQVRWFKGSQELQPGPKYELVSDGLYR-KLIISDV 2351
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIVE 140
+D+ YTC A G+ +A+ VE
Sbjct: 2352 HAEDEDTYTCDA----GDVKTSAQFFVE 2375
Score = 35.0 bits (79), Expect = 0.025
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
ES +D + A L P V + S + + EG A F C + D VVWF+D
Sbjct: 1881 ESRDDHTSAQLTVSV---PRVVKFMSG-LSTVVAEEGGEATFQCVVSP-SDVAVVWFRDG 1935
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 131
++ S F I + SL ISD+ +D + T +A + A
Sbjct: 1936 ALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQITVEAEGASSSA 1979
Score = 34.3 bits (77), Expect = 0.043
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 7/105 (6%)
Query: 50 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
+F +R E +EG+ A C++ E W K +S+R+ + D C L I
Sbjct: 3363 HFIGRLRHQESIEGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQD-GAVCELQI 3419
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
+ D +Y+C GE +A L V+ + EG EE
Sbjct: 3420 CGLAVADAGEYSCVC----GEERTSATLTVKALPAKFTEGLRNEE 3460
Score = 34.3 bits (77), Expect = 0.043
Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 41 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV---VWFKDDQSIRESRHFQI 97
A+ K K + + ++E +EG A F+C++ PEV W DD+ + S + ++
Sbjct: 4332 AQLKVTAKNTVVRGLENVEALEGGEALFECQLS---QPEVAAHTWLLDDEPVHTSENAEV 4388
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ E+G L++ D +C+ G+ +A L V
Sbjct: 4389 VFFENGLRHLLLLKNLRPQD---SCRVTFLAGDMVTSAFLTV 4427
Score = 32.7 bits (73), Expect = 0.13
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 57 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCG 114
+++ G+ A C++ P EV W+KD + + S ++ E C+ L++ V
Sbjct: 1175 EVQAEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRM---EVKGCTRRLVVQQVGK 1230
Query: 115 DDDAKYTCKA 124
D +Y+C+A
Sbjct: 1231 ADAGEYSCEA 1240
Score = 32.3 bits (72), Expect = 0.16
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
K + D V G C++ P V W KD ++IR+S+ + + E L+I
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDV-VCEGTMAMLVIRGA 2888
Query: 113 CGDDDAKYTCKAVNSLGEATCTAE 136
D +YTC+ S A+ E
Sbjct: 2889 SLKDAGEYTCEVEASKSTASLHVE 2912
Score = 32.3 bits (72), Expect = 0.16
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F++ +R+ E VEG+ A C++ E W K +++R+ + I E C L I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCELQIC 3508
Query: 111 DVCGDDDAKYTCKAVNSLGEATCT 134
+ D +Y C AT T
Sbjct: 3509 GLAMADAGEYLCVCGQERTSATLT 3532
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+ D++V EGS+A F C+I V WF D + + +ID G L + +
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070
Query: 115 DDDAKYTCKAVNSLGEATC---------TAELIVETMEEGE 146
D +A + A + EL T+ EGE
Sbjct: 3071 KDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE 3111
Score = 31.2 bits (69), Expect = 0.37
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC--SLIISDVCGDDDAKY 120
G++A C++ EV W+KD + + S +I E C L++ D +Y
Sbjct: 1273 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRI---EAAGCMRQLVVQQAGQADAGEY 1328
Query: 121 TCKA 124
TC+A
Sbjct: 1329 TCEA 1332
Score = 31.2 bits (69), Expect = 0.37
Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVC 113
R+++ G++A C++ EV W+KD + + S ++ E C+ L++
Sbjct: 1634 REVQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRV---EAVGCTRRLVVQQAG 1689
Query: 114 GDDDAKYTCKA 124
D +Y+C+A
Sbjct: 1690 QADAGEYSCEA 1700
Score = 30.0 bits (66), Expect = 0.82
Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
++ V G A+F+C+ V W+KD + S + D L+ + V D+
Sbjct: 807 VDAVAGGPAQFECETSE-AHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDE 865
Query: 118 AKYTCK 123
Y+C+
Sbjct: 866 GTYSCR 871
Score = 29.3 bits (64), Expect = 1.4
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 13/97 (13%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV-WFKDDQSIRESRHFQIDYDEDGNCS 106
+P KT R+L+ V S + P P+ V W+KDD + S F++ E
Sbjct: 2473 RPLEPKTGRELQSVVLSC-------DFRPAPKAVQWYKDDTPLSPSEKFKMSL-EGQMAE 2524
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
L I + D Y C+A G A + E+ VE E
Sbjct: 2525 LRILRLMPADAGVYRCQA----GSAHSSTEVTVEARE 2557
Score = 28.9 bits (63), Expect = 1.8
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 8/90 (8%)
Query: 52 SKTIRDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
+K ++ +EV+EG + F+C + E DP +W +++ S FQ G +++
Sbjct: 2739 TKRLKTMEVLEGESCSFECVLSHESASDP-AMWTVGGKTVGSSSRFQA--TRQGRKYILV 2795
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
DA +V L T A LIV
Sbjct: 2796 VREAAPSDAGEVVFSVRGL---TSKASLIV 2822
Score = 27.7 bits (60), Expect = 4.1
Identities = 17/76 (22%), Positives = 31/76 (40%), Gaps = 2/76 (2%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV-WFKDDQSIRESRHFQIDYDEDGNCS 106
+P F ++ LE G AR C++ VV W K+ + +++ +
Sbjct: 4067 RPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEM-RSQGATRE 4125
Query: 107 LIISDVCGDDDAKYTC 122
L+I + D +Y C
Sbjct: 4126 LLIHQLEAKDTGEYAC 4141
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 71.2 bits (173), Expect = 3e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F +++ EV +G FDC + G P P V WFKD + + E H+ I+ D+ G LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I+ V D Y C A NS+G ++ AEL V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217
Score = 68.6 bits (166), Expect = 2e-12
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 101
E K P FS T D E G A R +C + D W KD + + RH ID
Sbjct: 4891 EMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG 4950
Query: 102 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 153
DG CSL+I+ + D YTC+ N G+ T +A ++V E+ E GE ++
Sbjct: 4951 DGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDD 5005
Score = 63.9 bits (154), Expect = 5e-11
Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P TI D++ G A+F+ IEG P P V W+KD + +S E SL+
Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLS-QQQEGTTYSLV 6415
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
+ V D YTC A N+ G+ C AEL+V G+ E + E++
Sbjct: 6416 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV---LGGDNEPDSEKQ 6458
Score = 63.5 bits (153), Expect = 7e-11
Identities = 25/92 (27%), Positives = 49/92 (53%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F + + D G + C++ G P P + W+KD ++++ H + D DG+C+LI
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ + G D +Y C A ++ G + +++V+
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ 6105
Score = 62.0 bits (149), Expect = 2e-10
Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ-IDYDEDGNC 105
V P F +R VEG A+F C IEG P P++ W+KD + FQ + G
Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165
Query: 106 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 141
L+I +D Y C+ VN LG A +AEL +++
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 59.7 bits (143), Expect = 1e-09
Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Query: 49 PYFSKTIRDLEVVEGSA-ARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
P + +RDL+V G+ A+F K++GYP P + WFKD Q + S H ++ D+ +L
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTL 5318
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
I V +D +Y N++G A +A L+V +E E
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE 5357
Score = 53.9 bits (128), Expect = 5e-08
Identities = 35/99 (35%), Positives = 43/99 (43%), Gaps = 2/99 (2%)
Query: 41 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 100
AE P P S R V EG AR C + G P PE VW KD Q + E R + D
Sbjct: 232 AEGAPASPP--STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYED 289
Query: 101 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
N L I D YTC A N +G+ + ++V
Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 52.4 bits (124), Expect = 2e-07
Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
Query: 39 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 98
A AE+ PH F + V EGS A F C++ G P P V W KD + + E ++
Sbjct: 104 ACAEQAPH----FLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVR 159
Query: 99 YDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 141
+E G S L I D Y +A N LG A+ A L+V++
Sbjct: 160 VEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203
Score = 52.0 bits (123), Expect = 2e-07
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F + V G A C+I G P P+V W KD Q + F++ D D L
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLT 68
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I D+ D +Y C+A N++GEA L V+
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100
Score = 48.1 bits (113), Expect = 3e-06
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F K ++DLEV E +A F C++ P E WFK++ + S + I+ +E L +
Sbjct: 335 FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIE-EEGTERRLTVR 392
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+V DDDA Y C+ + AEL V+
Sbjct: 393 NVSADDDAVYICETPEG---SRTVAELAVQ 419
Score = 47.8 bits (112), Expect = 4e-06
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 42 EEKPH-------VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH 94
EEKP V P + +V +GS+ F K+EG P P V W +++ E
Sbjct: 5357 EEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---ERGV 5413
Query: 95 FQIDYDEDGNC--------SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
I D G SL++ DV YTC A N+ G+A C+A L V + + E
Sbjct: 5414 LWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473
Query: 147 GEGEEEE 153
+ + +E
Sbjct: 5474 EQEKVKE 5480
Score = 43.5 bits (101), Expect = 7e-05
Identities = 26/89 (29%), Positives = 35/89 (39%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F + + D VV G + C++ P + W KD + S I L
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 137
I V +D YTC N+LG T T L
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 46 HVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 104
H +P F + ++DLEV+EG AA C + P V W + +R + + E
Sbjct: 3181 HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSL-RQEGAM 3238
Query: 105 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 142
L++ ++ D +Y+C S G+ T +A L V +
Sbjct: 3239 LELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTAL 3272
Score = 37.0 bits (84), Expect = 0.007
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
+P F + ++ L+ EGS A C++ P VVW K ++ + + + L
Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRL-QGCTAEL 3946
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCT 134
++ D+ +D +YTC + AT T
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLT 3973
Score = 36.6 bits (83), Expect = 0.009
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
+ +RD +E +C++ +V WFK Q ++ +++ D LIISDV
Sbjct: 2294 RPLRDKIAMEKHRGVLECQVSR-ASAQVRWFKGSQELQPGPKYELVSDGLYR-KLIISDV 2351
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIVE 140
+D+ YTC A G+ +A+ VE
Sbjct: 2352 HAEDEDTYTCDA----GDVKTSAQFFVE 2375
Score = 35.0 bits (79), Expect = 0.025
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
ES +D + A L P V + S + + EG A F C + D VVWF+D
Sbjct: 1881 ESRDDHTSAQLTVSV---PRVVKFMSG-LSTVVAEEGGEATFQCVVSP-SDVAVVWFRDG 1935
Query: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 131
++ S F I + SL ISD+ +D + T +A + A
Sbjct: 1936 ALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQITVEAEGASSSA 1979
Score = 34.3 bits (77), Expect = 0.043
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 7/105 (6%)
Query: 50 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
+F +R E +EG+ A C++ E W K +S+R+ + D C L I
Sbjct: 3363 HFIGRLRHQESIEGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQD-GAVCELQI 3419
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
+ D +Y+C GE +A L V+ + EG EE
Sbjct: 3420 CGLAVADAGEYSCVC----GEERTSATLTVKALPAKFTEGLRNEE 3460
Score = 34.3 bits (77), Expect = 0.043
Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 41 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV---VWFKDDQSIRESRHFQI 97
A+ K K + + ++E +EG A F+C++ PEV W DD+ + S + ++
Sbjct: 4332 AQLKVTAKNTVVRGLENVEALEGGEALFECQLS---QPEVAAHTWLLDDEPVHTSENAEV 4388
Query: 98 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ E+G L++ D +C+ G+ +A L V
Sbjct: 4389 VFFENGLRHLLLLKNLRPQD---SCRVTFLAGDMVTSAFLTV 4427
Score = 32.7 bits (73), Expect = 0.13
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 57 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCG 114
+++ G+ A C++ P EV W+KD + + S ++ E C+ L++ V
Sbjct: 1175 EVQAEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRM---EVKGCTRRLVVQQVGK 1230
Query: 115 DDDAKYTCKA 124
D +Y+C+A
Sbjct: 1231 ADAGEYSCEA 1240
Score = 32.3 bits (72), Expect = 0.16
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 53 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 112
K + D V G C++ P V W KD ++IR+S+ + + E L+I
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDV-VCEGTMAMLVIRGA 2888
Query: 113 CGDDDAKYTCKAVNSLGEATCTAE 136
D +YTC+ S A+ E
Sbjct: 2889 SLKDAGEYTCEVEASKSTASLHVE 2912
Score = 32.3 bits (72), Expect = 0.16
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 51 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 110
F++ +R+ E VEG+ A C++ E W K +++R+ + I E C L I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCELQIC 3508
Query: 111 DVCGDDDAKYTCKAVNSLGEATCT 134
+ D +Y C AT T
Sbjct: 3509 GLAMADAGEYLCVCGQERTSATLT 3532
Score = 32.0 bits (71), Expect = 0.22
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 114
+ D++V EGS+A F C+I V WF D + + +ID G L + +
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070
Query: 115 DDDAKYTCKAVNSLGEATC---------TAELIVETMEEGE 146
D +A + A + EL T+ EGE
Sbjct: 3071 KDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE 3111
Score = 31.2 bits (69), Expect = 0.37
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
Query: 63 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC--SLIISDVCGDDDAKY 120
G++A C++ EV W+KD + + S +I E C L++ D +Y
Sbjct: 1273 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRI---EAAGCMRQLVVQQAGQADAGEY 1328
Query: 121 TCKA 124
TC+A
Sbjct: 1329 TCEA 1332
Score = 31.2 bits (69), Expect = 0.37
Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 56 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVC 113
R+++ G++A C++ EV W+KD + + S ++ E C+ L++
Sbjct: 1634 REVQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRV---EAVGCTRRLVVQQAG 1689
Query: 114 GDDDAKYTCKA 124
D +Y+C+A
Sbjct: 1690 QADAGEYSCEA 1700
Score = 30.0 bits (66), Expect = 0.82
Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
++ V G A+F+C+ V W+KD + S + D L+ + V D+
Sbjct: 807 VDAVAGGPAQFECETSE-AHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDE 865
Query: 118 AKYTCK 123
Y+C+
Sbjct: 866 GTYSCR 871
Score = 29.3 bits (64), Expect = 1.4
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 13/97 (13%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV-WFKDDQSIRESRHFQIDYDEDGNCS 106
+P KT R+L+ V S + P P+ V W+KDD + S F++ E
Sbjct: 2473 RPLEPKTGRELQSVVLSC-------DFRPAPKAVQWYKDDTPLSPSEKFKMSL-EGQMAE 2524
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
L I + D Y C+A G A + E+ VE E
Sbjct: 2525 LRILRLMPADAGVYRCQA----GSAHSSTEVTVEARE 2557
Score = 28.9 bits (63), Expect = 1.8
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 8/90 (8%)
Query: 52 SKTIRDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 109
+K ++ +EV+EG + F+C + E DP +W +++ S FQ G +++
Sbjct: 2739 TKRLKTMEVLEGESCSFECVLSHESASDP-AMWTVGGKTVGSSSRFQA--TRQGRKYILV 2795
Query: 110 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
DA +V L T A LIV
Sbjct: 2796 VREAAPSDAGEVVFSVRGL---TSKASLIV 2822
Score = 27.7 bits (60), Expect = 4.1
Identities = 17/76 (22%), Positives = 31/76 (40%), Gaps = 2/76 (2%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV-WFKDDQSIRESRHFQIDYDEDGNCS 106
+P F ++ LE G AR C++ VV W K+ + +++ +
Sbjct: 4067 RPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEM-RSQGATRE 4125
Query: 107 LIISDVCGDDDAKYTC 122
L+I + D +Y C
Sbjct: 4126 LLIHQLEAKDTGEYAC 4141
>gi|115511036 alpha-kinase 3 [Homo sapiens]
Length = 1907
Score = 68.9 bits (167), Expect = 2e-12
Identities = 41/130 (31%), Positives = 61/130 (46%), Gaps = 2/130 (1%)
Query: 17 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 76
P + L++ +L F +A+ +P F T++ V E S RF C + GYP
Sbjct: 247 PETSLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRSVSEDSDVRFTCIVTGYP 306
Query: 77 DPEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAK-YTCKAVNSLGEATCT 134
+PEV W+KDD + R + + GN + C ++DA Y A NS G +C+
Sbjct: 307 EPEVTWYKDDTELDRYCGLPKYEITHQGNRHTLQLYRCREEDAAIYQASAQNSKGIVSCS 366
Query: 135 AELIVETMEE 144
L V TM E
Sbjct: 367 GVLEVGTMTE 376
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 65.9 bits (159), Expect = 1e-11
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 6/125 (4%)
Query: 21 LNAEKLESEEDVSQAFLEAVAEEKPHVK---PYFSKTIRDLEVVEGSAARFDCKIEGYPD 77
L ++ E EE+ + AE++ + P+F K +++ VV+ RF K+ G P
Sbjct: 551 LQKKREEEEEEEGSIMNGSTAEDEEQTRSGAPWFKKPLKNTSVVDSEPVRFTVKVTGEPK 610
Query: 78 PEVVWFKDDQSIRESRHFQIDYDEDGNC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
PE+ W+ + + +++ +Q Y E G L + + +D +Y CKAVN+ G A T
Sbjct: 611 PEITWWFEGEILQDGEDYQ--YIERGETYCLYLPETFPEDGGEYMCKAVNNKGSAASTCI 668
Query: 137 LIVET 141
L +E+
Sbjct: 669 LTIES 673
>gi|156104903 myomesin 2 [Homo sapiens]
Length = 1465
Score = 63.9 bits (154), Expect = 5e-11
Identities = 35/105 (33%), Positives = 51/105 (48%), Gaps = 9/105 (8%)
Query: 34 QAFLEAVAEEKPHVKPYFSKTIRD---------LEVVEGSAARFDCKIEGYPDPEVVWFK 84
QAF EA AE + F++ R + ++EG C + G PDPEV+WFK
Sbjct: 1321 QAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFK 1380
Query: 85 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 129
+DQ I+ S HF + ++ S+ I V +D KY+ N G
Sbjct: 1381 NDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425
Score = 38.5 bits (88), Expect = 0.002
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 4/108 (3%)
Query: 42 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI---RESRHFQID 98
EE+ P +R V E + + ++G+P P V W+KD I E ++I+
Sbjct: 147 EERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206
Query: 99 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
G +L I+ DD A Y+ A N+ G+ + A ++V E
Sbjct: 207 -SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDE 253
Score = 38.1 bits (87), Expect = 0.003
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 62 EGSAARFDCKIEGYPD-----PEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 116
EG C + PD P W++DD ++ES+ ++ + E G SL S + DD
Sbjct: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGE-GQASLSFSHLHKDD 349
Query: 117 DAKYTCKAVNSLGEATCTAELIV 139
+ YT + V+ G + +A L V
Sbjct: 350 EGLYTLRIVSRGGVSDHSAFLFV 372
>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
Length = 1141
Score = 61.2 bits (147), Expect = 3e-10
Identities = 39/101 (38%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 42 EEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 98
E K H + P F + D VV G +A +C + G+P P+VVW K+ IRE F I
Sbjct: 1038 EYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT 1097
Query: 99 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ G +L I D YTC+AVN LGEA +L V
Sbjct: 1098 -NYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
Score = 40.0 bits (92), Expect = 8e-04
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)
Query: 36 FLEAVAEEKPHVKP------YFSKTIRD-LEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 88
FLE E P +P KT + + VV G+ R D I G P P W K D+
Sbjct: 525 FLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDE- 583
Query: 89 IRESRHFQIDYDEDGNC-SLIISDVCGDDDAKYTCKAVNSLGE 130
+ + + ++ +C S +I +D+ +YT K N +GE
Sbjct: 584 VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE 626
>gi|148839296 immunoglobulin-like and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 868
Score = 59.3 bits (142), Expect = 1e-09
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
KP F +R + +G C ++G P P V WFK+D+S+ E D G CSL
Sbjct: 773 KPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSL-EGNPAVYSTDLLGVCSL 831
Query: 108 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
I V D +Y A N+LG+A TA LIV
Sbjct: 832 TIPSVSPKDSGEYKAVAENTLGQAVSTATLIV 863
Score = 40.0 bits (92), Expect = 8e-04
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 50 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC-SLI 108
+FS+ + D+EV G AA C + P WFKD ++ + + + +DG SL
Sbjct: 74 HFSQGLADMEVQPGEAATLSCTLTSDLGPG-TWFKD--GVKLTTQDGVIFKQDGLVHSLF 130
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAE 136
I+ V G +YT A + EAT T +
Sbjct: 131 ITHVQGTQAGRYTFVAGDQQSEATLTVQ 158
Score = 28.9 bits (63), Expect = 1.8
Identities = 19/64 (29%), Positives = 24/64 (37%), Gaps = 3/64 (4%)
Query: 58 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 117
L V G R E P PEV W KD + + + +DG L+I D
Sbjct: 575 LTVKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKR---SVTVTKDGLTQLLIPVAGLSDS 631
Query: 118 AKYT 121
YT
Sbjct: 632 GLYT 635
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform
1 precursor [Homo sapiens]
Length = 1907
Score = 57.8 bits (138), Expect = 4e-09
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
KP F K D + G A F C+ G P P + W K + + R I++D+ L
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 108 IISDV-CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I + D+A Y C A NSLGE +A+L V E+
Sbjct: 92 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQ 129
Score = 42.0 bits (97), Expect = 2e-04
Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 22/135 (16%)
Query: 23 AEKLESEEDVSQAFLEAVAEEKP---------------HVKPYFSKTIRDLEVVEGSAAR 67
A ++ES E+ Q E VA V P FS EV+ G +
Sbjct: 191 ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVN 250
Query: 68 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 127
C G P P V W + + + + G L +S+V A YTC A++S
Sbjct: 251 LTCVAVGAPMPYVKWMMGAEELTKEDEMPV-----GRNVLELSNVVRS--ANYTCVAISS 303
Query: 128 LGEATCTAELIVETM 142
LG TA++ V+ +
Sbjct: 304 LGMIEATAQVTVKAL 318
Score = 36.6 bits (83), Expect = 0.009
Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 10/77 (12%)
Query: 58 LEVVEGS-AARFDCKIEGYPDPEVVWFKD----DQSIRESRHFQIDYDEDGNCSLIISDV 112
L+VVE + A C G PDPE+ WFKD D + R Q+ + +L I
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-----RSGALQIESS 197
Query: 113 CGDDDAKYTCKAVNSLG 129
D KY C A NS G
Sbjct: 198 EESDQGKYECVATNSAG 214
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform
2 precursor [Homo sapiens]
Length = 1898
Score = 57.8 bits (138), Expect = 4e-09
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 48 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 107
KP F K D + G A F C+ G P P + W K + + R I++D+ L
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 108 IISDV-CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
I + D+A Y C A NSLGE +A+L V E+
Sbjct: 92 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQ 129
Score = 42.0 bits (97), Expect = 2e-04
Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 22/135 (16%)
Query: 23 AEKLESEEDVSQAFLEAVAEEKP---------------HVKPYFSKTIRDLEVVEGSAAR 67
A ++ES E+ Q E VA V P FS EV+ G +
Sbjct: 191 ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVN 250
Query: 68 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 127
C G P P V W + + + + G L +S+V A YTC A++S
Sbjct: 251 LTCVAVGAPMPYVKWMMGAEELTKEDEMPV-----GRNVLELSNVVRS--ANYTCVAISS 303
Query: 128 LGEATCTAELIVETM 142
LG TA++ V+ +
Sbjct: 304 LGMIEATAQVTVKAL 318
Score = 36.6 bits (83), Expect = 0.009
Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 10/77 (12%)
Query: 58 LEVVEGS-AARFDCKIEGYPDPEVVWFKD----DQSIRESRHFQIDYDEDGNCSLIISDV 112
L+VVE + A C G PDPE+ WFKD D + R Q+ + +L I
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-----RSGALQIESS 197
Query: 113 CGDDDAKYTCKAVNSLG 129
D KY C A NS G
Sbjct: 198 EESDQGKYECVATNSAG 214
>gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor
[Homo sapiens]
Length = 1338
Score = 57.0 bits (136), Expect = 6e-09
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
PY + + D V S+ DC G P+P++ WFK++ I++ + G+ +L
Sbjct: 661 PYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILG---PGSSTLF 717
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
I V +D+ Y CKA N G +A L V+
Sbjct: 718 IERVTEEDEGVYHCKATNQKGSVESSAYLTVQ 749
Score = 39.7 bits (91), Expect = 0.001
Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 9/67 (13%)
Query: 58 LEVVEGSAA-RFDCKIEGYPDPEVVWFKDDQSIRE--SRHFQIDYDEDGNCSLIISDVCG 114
LE V G + R K++ +P PEVVW KD E +R+ Y SLII DV
Sbjct: 344 LETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGY------SLIIKDVTE 397
Query: 115 DDDAKYT 121
+D YT
Sbjct: 398 EDAGNYT 404
>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
Length = 1274
Score = 56.6 bits (135), Expect = 8e-09
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
P F++ + + V+ G A C + G P P++ WFK+ + E F++ + + G +L
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLE 1239
Query: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
I C D Y C+A N GEA C L V
Sbjct: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 32.0 bits (71), Expect = 0.22
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 59 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 118
+V +G R ++ + D EV W K+ Q I+ S I +L IS DDA
Sbjct: 374 QVSKGHKIRLTVELADH-DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDA 432
Query: 119 KYTCKAVNSLGEATCTAELIVE 140
Y C +G C+ EL V+
Sbjct: 433 AYQC----VVGGEKCSTELFVK 450
Score = 31.6 bits (70), Expect = 0.28
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
Query: 52 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSLIIS 110
++ + D V+ G F+C++ +V W KD + F+ + +DG LII+
Sbjct: 457 TRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIIN 515
Query: 111 DVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
+ +D Y S G+A AELIV+
Sbjct: 516 EAMLEDAGHYA--LCTSGGQA--LAELIVQ 541
Score = 27.3 bits (59), Expect = 5.3
Identities = 12/25 (48%), Positives = 14/25 (56%)
Query: 60 VVEGSAARFDCKIEGYPDPEVVWFK 84
VV G+ R D I G P P V+W K
Sbjct: 661 VVAGNKLRLDVPISGDPAPTVIWQK 685
>gi|209693444 myotilin isoform b [Homo sapiens]
Length = 314
Score = 56.6 bits (135), Expect = 8e-09
Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 5/127 (3%)
Query: 17 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 76
PTS + + S DV+ +A+ E+ P F + ++ + EG R D K+ G P
Sbjct: 39 PTSQVRSRST-SRGDVNDQ--DAIQEK--FYPPRFIQVPENMSIDEGRFCRMDFKVSGLP 93
Query: 77 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
P+V W+ + ++++ ++ E G SLI V D Y C A N GEAT T +
Sbjct: 94 APDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
Query: 137 LIVETME 143
L V E
Sbjct: 154 LDVLAKE 160
Score = 54.7 bits (130), Expect = 3e-08
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 37 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHF 95
L+ +A+E P F + +V+EG + + +C+I P P++ W ++++ ++ +
Sbjct: 154 LDVLAKEHKRA-PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
Query: 96 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ D G +L+I DV D YT AVN G TC L V
Sbjct: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
>gi|5803106 myotilin isoform a [Homo sapiens]
Length = 498
Score = 56.6 bits (135), Expect = 8e-09
Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 5/127 (3%)
Query: 17 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 76
PTS + + S DV+ +A+ E+ P F + ++ + EG R D K+ G P
Sbjct: 223 PTSQVRSRST-SRGDVNDQ--DAIQEK--FYPPRFIQVPENMSIDEGRFCRMDFKVSGLP 277
Query: 77 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
P+V W+ + ++++ ++ E G SLI V D Y C A N GEAT T +
Sbjct: 278 APDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 337
Query: 137 LIVETME 143
L V E
Sbjct: 338 LDVLAKE 344
Score = 54.7 bits (130), Expect = 3e-08
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 37 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHF 95
L+ +A+E P F + +V+EG + + +C+I P P++ W ++++ ++ +
Sbjct: 338 LDVLAKEHKRA-PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 396
Query: 96 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
+ D G +L+I DV D YT AVN G TC L V
Sbjct: 397 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 440
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 56.6 bits (135), Expect = 8e-09
Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 46 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD---DQSIRESRHFQIDYDED 102
+V P F+KT D+ + + AR +C G+P+P++ W KD D R + D+D
Sbjct: 596 NVLPSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDD 655
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
I+DV DD Y+C A NS G + A L V
Sbjct: 656 ---VFFITDVKIDDAGVYSCTAQNSAGSISANATLTV 689
Score = 51.6 bits (122), Expect = 3e-07
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 55 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ--SIRESRHFQIDYDEDGNCSLIISDV 112
+ D V G CK G P P + WFK D+ S+ E H D N L++ +V
Sbjct: 699 LEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD-----NQLLVVQNV 753
Query: 113 CGDDDAKYTCKAVNSLGEATCTAELIV 139
+D +YTC+ N+LG ++L V
Sbjct: 754 VAEDAGRYTCEMSNTLGTERAHSQLSV 780
>gi|11321597 kinase insert domain receptor precursor [Homo sapiens]
Length = 1356
Score = 55.5 bits (132), Expect = 2e-08
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 3/98 (3%)
Query: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
V P + + + G + C G P P+++WFKD++++ E + +DGN +
Sbjct: 665 VAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVL---KDGNRN 721
Query: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 144
L I V +D+ YTC+A + LG A A I+E +E
Sbjct: 722 LTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQE 759
Score = 33.5 bits (75), Expect = 0.074
Identities = 23/88 (26%), Positives = 35/88 (39%), Gaps = 9/88 (10%)
Query: 46 HVKPY--FSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
H KP+ F + L E G R K GYP PE+ W+K+ + + + +
Sbjct: 325 HEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPLESNHTIKAGH--- 381
Query: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGE 130
L I +V D YT N + +
Sbjct: 382 ---VLTIMEVSERDTGNYTVILTNPISK 406
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 55.1 bits (131), Expect = 2e-08
Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 4/100 (4%)
Query: 41 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 100
A E+P P F K +D V G A F C+ G P P V W K + + R I++D
Sbjct: 28 AAEEP---PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFD 84
Query: 101 EDGNCSLIISDV-CGDDDAKYTCKAVNSLGEATCTAELIV 139
E L I + D+ Y C A NS+GE T A+L V
Sbjct: 85 ESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTV 124
Score = 43.9 bits (102), Expect = 5e-05
Identities = 37/144 (25%), Positives = 56/144 (38%), Gaps = 26/144 (18%)
Query: 23 AEKLESEEDVSQAFLEAVA-------------------EEKPHVKPYFSKTIRDLEVVEG 63
A ++ES E+ Q E VA E V P FS E++ G
Sbjct: 191 ALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPG 250
Query: 64 SAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCK 123
C G P P V W + + + + G L ++DV D A YTC
Sbjct: 251 GNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV-----GRNVLELTDV--KDSANYTCV 303
Query: 124 AVNSLGEATCTAELIVETMEEGEG 147
A++SLG A++ V+++ + G
Sbjct: 304 AMSSLGVIEAVAQITVKSLPKAPG 327
Score = 39.7 bits (91), Expect = 0.001
Identities = 33/93 (35%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
Query: 58 LEVVEGS-AARFDCKIEGYPDPEVVWFKD----DQSIRESRHFQIDYDEDGNCSLIISDV 112
L+VVE + A C G PDPE+ WFKD D S R Q+ + +L I
Sbjct: 143 LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQL-----RSGALQIESS 197
Query: 113 CGDDDAKYTCKAVNSLG-EATCTAELIVETMEE 144
D KY C A NS G + A L V + E
Sbjct: 198 EETDQGKYECVATNSAGVRYSSPANLYVRELRE 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,475,974
Number of Sequences: 37866
Number of extensions: 277127
Number of successful extensions: 2992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 1102
Number of HSP's gapped (non-prelim): 1505
length of query: 154
length of database: 18,247,518
effective HSP length: 93
effective length of query: 61
effective length of database: 14,725,980
effective search space: 898284780
effective search space used: 898284780
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.