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Search of human proteins with 16950623
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens]
(153 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens] 311 1e-85
gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens] 306 3e-84
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 306 3e-84
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 306 3e-84
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 306 3e-84
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 306 3e-84
gi|157785645 SPEG complex locus [Homo sapiens] 85 2e-17
gi|153792294 myopalladin [Homo sapiens] 83 1e-16
gi|110349721 titin isoform novex-3 [Homo sapiens] 80 7e-16
gi|110349719 titin isoform N2-A [Homo sapiens] 80 7e-16
gi|110349717 titin isoform novex-2 [Homo sapiens] 80 7e-16
gi|110349713 titin isoform novex-1 [Homo sapiens] 80 7e-16
gi|110349715 titin isoform N2-B [Homo sapiens] 80 7e-16
gi|93102361 palladin [Homo sapiens] 77 6e-15
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 71 3e-13
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 71 3e-13
gi|115511036 alpha-kinase 3 [Homo sapiens] 66 1e-11
gi|156104903 myomesin 2 [Homo sapiens] 64 5e-11
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 63 1e-10
gi|133908641 myosin binding protein C, fast type [Homo sapiens] 61 3e-10
gi|209693444 myotilin isoform b [Homo sapiens] 59 1e-09
gi|5803106 myotilin isoform a [Homo sapiens] 59 1e-09
gi|148839296 immunoglobulin-like and fibronectin type III domain... 59 1e-09
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 58 4e-09
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 58 4e-09
gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor [... 57 6e-09
gi|148596957 myosin binding protein C, cardiac [Homo sapiens] 57 8e-09
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 57 8e-09
gi|11321597 kinase insert domain receptor precursor [Homo sapiens] 55 2e-08
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 55 2e-08
>gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens]
Length = 153
Score = 311 bits (797), Expect = 1e-85
Identities = 153/153 (100%), Positives = 153/153 (100%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV 60
MAMISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV
Sbjct: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV 60
Query: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT
Sbjct: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
Query: 121 CKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
CKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 121 CKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
>gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens]
Length = 154
Score = 306 bits (785), Expect = 3e-84
Identities = 153/154 (99%), Positives = 153/154 (99%), Gaps = 1/154 (0%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 59
MAMISGLSGRKSSTGSPTSPLNAEKLESE DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60
Query: 60 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 119
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
Query: 120 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 306 bits (785), Expect = 3e-84
Identities = 153/154 (99%), Positives = 153/154 (99%), Gaps = 1/154 (0%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 59
MAMISGLSGRKSSTGSPTSPLNAEKLESE DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1710 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1769
Query: 60 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 119
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
Query: 120 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1830 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
Score = 71.6 bits (174), Expect = 2e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I V +D KYTC+A N G T EL VE
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 67.8 bits (164), Expect = 3e-12
Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
Query: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
+L VA KP P F + + DL+V++GS ++ G P PEV+W + I+ES F
Sbjct: 611 YLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 144
+ SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 670 HFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718
Score = 63.5 bits (153), Expect = 7e-11
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
Query: 28 SEDVSQAFLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
S+ + F E +P + P F+ + + V EG RF CKI G P P+V W K
Sbjct: 137 SKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
+ ++ S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 197 GNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 60.5 bits (145), Expect = 6e-10
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 567
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Score = 56.6 bits (135), Expect = 8e-09
Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
Query: 18 TSPLNAEKLESEDV-SQAFLEAVAEE--KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 74
T P L S+DV S+A + E + P F + EV E +F C++ G
Sbjct: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
Query: 75 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 134
P PEV WF + +R Y++ G+ L + D Y+C A N+ G+ +C+
Sbjct: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
Query: 135 ELIVETM 141
L VE +
Sbjct: 501 TLQVERL 507
Score = 52.4 bits (124), Expect = 2e-07
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1150
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
Score = 44.3 bits (103), Expect = 4e-05
Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 42 EKPH--VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDY 98
++PH +P+F R + G + C I G P P V W +D +++ +++ HF++
Sbjct: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
Query: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ED +L++ V +Y N +GE +C L+++
Sbjct: 773 NED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
Score = 32.7 bits (73), Expect = 0.12
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
Query: 103 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ I++ + CG YT N LG L V
Sbjct: 1293 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1327
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 306 bits (785), Expect = 3e-84
Identities = 153/154 (99%), Positives = 153/154 (99%), Gaps = 1/154 (0%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 59
MAMISGLSGRKSSTGSPTSPLNAEKLESE DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1761 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1820
Query: 60 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 119
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 1821 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1880
Query: 120 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1881 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914
Score = 71.6 bits (174), Expect = 2e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I V +D KYTC+A N G T EL VE
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 67.8 bits (164), Expect = 3e-12
Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
Query: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
+L VA KP P F + + DL+V++GS ++ G P PEV+W + I+ES F
Sbjct: 611 YLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 144
+ SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 670 HFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718
Score = 63.5 bits (153), Expect = 7e-11
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
Query: 28 SEDVSQAFLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
S+ + F E +P + P F+ + + V EG RF CKI G P P+V W K
Sbjct: 137 SKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
+ ++ S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 197 GNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 60.5 bits (145), Expect = 6e-10
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 567
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Score = 56.6 bits (135), Expect = 8e-09
Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
Query: 18 TSPLNAEKLESEDV-SQAFLEAVAEE--KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 74
T P L S+DV S+A + E + P F + EV E +F C++ G
Sbjct: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
Query: 75 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 134
P PEV WF + +R Y++ G+ L + D Y+C A N+ G+ +C+
Sbjct: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
Query: 135 ELIVETM 141
L VE +
Sbjct: 501 TLQVERL 507
Score = 52.4 bits (124), Expect = 2e-07
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1150
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
Score = 44.3 bits (103), Expect = 4e-05
Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 42 EKPH--VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDY 98
++PH +P+F R + G + C I G P P V W +D +++ +++ HF++
Sbjct: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
Query: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ED +L++ V +Y N +GE +C L+++
Sbjct: 773 NED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
Score = 32.7 bits (73), Expect = 0.12
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
Query: 103 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ I++ + CG YT N LG L V
Sbjct: 1293 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1327
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 306 bits (785), Expect = 3e-84
Identities = 153/154 (99%), Positives = 153/154 (99%), Gaps = 1/154 (0%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 59
MAMISGLSGRKSSTGSPTSPLNAEKLESE DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1641 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1700
Query: 60 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 119
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 1701 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1760
Query: 120 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1761 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
Score = 71.6 bits (174), Expect = 2e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I V +D KYTC+A N G T EL VE
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 67.8 bits (164), Expect = 3e-12
Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
Query: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
+L VA KP P F + + DL+V++GS ++ G P PEV+W + I+ES F
Sbjct: 542 YLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 144
+ SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 601 HFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 649
Score = 63.5 bits (153), Expect = 7e-11
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
Query: 28 SEDVSQAFLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
S+ + F E +P + P F+ + + V EG RF CKI G P P+V W K
Sbjct: 137 SKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
+ ++ S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 197 GNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 60.5 bits (145), Expect = 6e-10
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 498
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 52.4 bits (124), Expect = 2e-07
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1081
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
Score = 44.3 bits (103), Expect = 4e-05
Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 42 EKPH--VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDY 98
++PH +P+F R + G + C I G P P V W +D +++ +++ HF++
Sbjct: 644 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 703
Query: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ED +L++ V +Y N +GE +C L+++
Sbjct: 704 NED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
Score = 32.7 bits (73), Expect = 0.12
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 1164 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1223
Query: 103 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ I++ + CG YT N LG L V
Sbjct: 1224 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1258
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 306 bits (785), Expect = 3e-84
Identities = 153/154 (99%), Positives = 153/154 (99%), Gaps = 1/154 (0%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 59
MAMISGLSGRKSSTGSPTSPLNAEKLESE DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1692 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1751
Query: 60 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 119
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 1752 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1811
Query: 120 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1812 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1845
Score = 71.6 bits (174), Expect = 2e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I V +D KYTC+A N G T EL VE
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 67.8 bits (164), Expect = 3e-12
Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
Query: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
+L VA KP P F + + DL+V++GS ++ G P PEV+W + I+ES F
Sbjct: 542 YLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 144
+ SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 601 HFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 649
Score = 63.5 bits (153), Expect = 7e-11
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
Query: 28 SEDVSQAFLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
S+ + F E +P + P F+ + + V EG RF CKI G P P+V W K
Sbjct: 137 SKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
+ ++ S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 197 GNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 60.5 bits (145), Expect = 6e-10
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 498
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 52.4 bits (124), Expect = 2e-07
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1081
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
Score = 44.3 bits (103), Expect = 4e-05
Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 42 EKPH--VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDY 98
++PH +P+F R + G + C I G P P V W +D +++ +++ HF++
Sbjct: 644 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 703
Query: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ED +L++ V +Y N +GE +C L+++
Sbjct: 704 NED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
Score = 32.7 bits (73), Expect = 0.12
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 1164 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1223
Query: 103 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ I++ + CG YT N LG L V
Sbjct: 1224 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1258
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 85.1 bits (209), Expect = 2e-17
Identities = 44/108 (40%), Positives = 61/108 (56%), Gaps = 4/108 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F + D+EV G ARF +EG P P+++W+KD+ + ES H Y+E+ CSL+
Sbjct: 1485 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEEN-ECSLV 1543
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 152
+ D YTC A N GE +C AEL V +T E EG GE+E+
Sbjct: 1544 VLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDED 1591
Score = 78.2 bits (191), Expect = 3e-15
Identities = 41/97 (42%), Positives = 59/97 (60%), Gaps = 1/97 (1%)
Query: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
+P + P F++ + D+EV+EG AARFDCKI G P P V W + ES + ++ D G
Sbjct: 1059 RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQD-GG 1117
Query: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
SL I+ V +D+ Y AVN+ G+A C+A+L VE
Sbjct: 1118 LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154
Score = 57.8 bits (138), Expect = 4e-09
Identities = 39/128 (30%), Positives = 58/128 (45%), Gaps = 9/128 (7%)
Query: 11 KSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 70
K PTSP +LES D S A E+P P F ++++ V G+ C
Sbjct: 693 KGRRARPTSP----ELESSDDSYVS----AGEEPLEAPVFEIPLQNVVVAPGADVLLKCI 744
Query: 71 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 130
I P P+V W KD ++R + + + + +L++ + D Y A N LG+A
Sbjct: 745 ITANPPPQVSWHKDGSALRSEGRLLLRAEGERH-TLLLREARAADAGSYMATATNELGQA 803
Query: 131 TCTAELIV 138
TC A L V
Sbjct: 804 TCAASLTV 811
Score = 55.1 bits (131), Expect = 2e-08
Identities = 32/96 (33%), Positives = 42/96 (43%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F ++ D V EG +++G P P V W ++ Q +R + + E G C L
Sbjct: 869 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
I D YTCKAVN G C A L V E
Sbjct: 929 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPE 964
Score = 48.9 bits (115), Expect = 2e-06
Identities = 43/153 (28%), Positives = 62/153 (40%), Gaps = 17/153 (11%)
Query: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVV 60
M G G + T +P SP K AVA P F + +++ V
Sbjct: 1 MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGGGAPVAVAGA-----PVFLRPLKNAAVC 55
Query: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KY 119
GS R + G P P + WF+D Q + + +C + CG DA Y
Sbjct: 56 AGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPA-------PEPSCLWLRR--CGAQDAGVY 106
Query: 120 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 152
+C A N G A+C A L V +E G+ E E++
Sbjct: 107 SCMAQNERGRASCEAVLTV--LEVGDSETAEDD 137
Score = 48.9 bits (115), Expect = 2e-06
Identities = 36/138 (26%), Positives = 59/138 (42%), Gaps = 7/138 (5%)
Query: 11 KSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 70
+++ P+S L E+ Q LE ++ P F + ++DLEV A +C+
Sbjct: 1157 RTAASGPSSKLEKMPSIPEEPEQGELERLSI------PDFLRPLQDLEVGLAKEAMLECQ 1210
Query: 71 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 130
+ G P P + WF + I+ S ++ D + L+ V Y N LG+A
Sbjct: 1211 VTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVH-RLVFPAVGPQHAGVYKSVIANKLGKA 1269
Query: 131 TCTAELIVETMEEGEGEG 148
C A L V + G +G
Sbjct: 1270 ACYAHLYVTDVVPGPPDG 1287
Score = 48.5 bits (114), Expect = 2e-06
Identities = 26/85 (30%), Positives = 43/85 (50%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
++D++V G A F+C + G D EV W + ++ + + + C L+++ V
Sbjct: 974 LQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHE 1033
Query: 114 DDDAKYTCKAVNSLGEATCTAELIV 138
DD YTCK + E TC+A L V
Sbjct: 1034 DDSGVYTCKLSTAKDELTCSARLTV 1058
Score = 46.2 bits (108), Expect = 1e-05
Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 4/120 (3%)
Query: 19 SPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE 78
SP N E++ ++ + ++ P F ++D ++EG AA C P P
Sbjct: 2559 SPPNLSASVQEELGHQYVRSESD----FPPVFHIKLKDQVLLEGEAATLLCLPAACPAPH 2614
Query: 79 VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ W KD +S+R I +DG L I Y C A N LG T + + V
Sbjct: 2615 ISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 32.0 bits (71), Expect = 0.21
Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 13/101 (12%)
Query: 59 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH--FQIDYDEDGNCSLIISDVCGDDD 116
VVEG A + + +VVW ++ E+R +++ +D L I V D
Sbjct: 1401 VVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDM 1459
Query: 117 AKYTCKAVNSLGEATCTA----------ELIVETMEEGEGE 147
TC A N G TC+ E I+E +E G GE
Sbjct: 1460 GALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGE 1500
>gi|153792294 myopalladin [Homo sapiens]
Length = 1320
Score = 82.8 bits (203), Expect = 1e-16
Identities = 45/121 (37%), Positives = 64/121 (52%), Gaps = 4/121 (3%)
Query: 25 KLESEDVSQAFLEAVAEEKPHVK---PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVW 81
+LE V ++ E +E P K P F K ++ V EGS F CKI G P P+V W
Sbjct: 919 RLERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYW 978
Query: 82 FKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
FKD + I + + H ++ + DG CSL I DDD YT A N G +C+ L+V++
Sbjct: 979 FKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQS 1038
Query: 141 M 141
+
Sbjct: 1039 L 1039
Score = 64.3 bits (155), Expect = 4e-11
Identities = 32/108 (29%), Positives = 57/108 (52%), Gaps = 7/108 (6%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-------DYDE 100
P F+K +++L EG F+C+++G P P+V W+++ I +S F+I +
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 148
+ C+L+I++V +D +TC A N G + A+L V E+ G
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNG 542
Score = 63.5 bits (153), Expect = 7e-11
Identities = 35/114 (30%), Positives = 60/114 (52%), Gaps = 3/114 (2%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
EE P F++ +R EV EG+ + DC + G P P+V W+ + + + S I +
Sbjct: 262 EEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI--VQ 319
Query: 101 DGNC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
GN SL I++ +D +Y+C A N G + +AE+ +E + + EG+ +E
Sbjct: 320 AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKE 373
Score = 56.6 bits (135), Expect = 8e-09
Identities = 30/96 (31%), Positives = 45/96 (46%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
+P+F + D+ EG R DCK+ G P PE+ W + Q + ++ E G SL
Sbjct: 1072 RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSL 1131
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
+I + D Y C A N G+ + + EL V E
Sbjct: 1132 LIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167
Score = 50.8 bits (120), Expect = 4e-07
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 36 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR-HF 94
L VA+E P + +++ V EG R +C++ G P P W KD+++I +R
Sbjct: 1161 LSVVAKEVKKA-PVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERI 1219
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 136
+ D G L+I D YT A N G +CTA L
Sbjct: 1220 SMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARL 1261
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 80.1 bits (196), Expect = 7e-16
Identities = 40/116 (34%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E+L ED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+K
Sbjct: 1268 EELLEEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK 1326
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
D + I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1327 DGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382
Score = 75.5 bits (184), Expect = 2e-14
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E P P ++++ V+EG + +C I GYP P V W+++D I S FQI + +
Sbjct: 937 EIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QS 995
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
G L+I + +D ++TC AVN G + + L V+ EE E E
Sbjct: 996 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKE 1041
Score = 70.1 bits (170), Expect = 7e-13
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 105
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 68.2 bits (165), Expect = 3e-12
Identities = 42/121 (34%), Positives = 59/121 (48%), Gaps = 4/121 (3%)
Query: 22 NAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVW 81
N + E ED + ++ E P P F I D ++ E S A F C + G P PEV W
Sbjct: 5358 NMDSREGED-KELKIDLEVFEMP---PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKW 5413
Query: 82 FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
+K+ I + +E G+ +L I +VC D A Y C+AVN +GEA C L +
Sbjct: 5414 YKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDS 5473
Query: 142 E 142
E
Sbjct: 5474 E 5474
Score = 67.8 bits (164), Expect = 3e-12
Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 21 LNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 80
L A + S A L AE P P F + ++ + V +GS R ++ G P P V
Sbjct: 80 LKATNGSGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 81 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
+++D I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+
Sbjct: 137 FYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Query: 141 MEE 143
EE
Sbjct: 196 EEE 198
Score = 63.5 bits (153), Expect = 7e-11
Identities = 44/127 (34%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 16 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 75
SP +LE D SQ LE + KP F + +EG ARFD K+ G P
Sbjct: 1433 SPARMSPGRRLEETDESQ--LERL------YKPVFVLKPVSFKCLEGQTARFDLKVVGRP 1484
Query: 76 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 135
PE WF D Q I ++ EDG SLII D ++T A N G ++ +
Sbjct: 1485 MPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVI 1544
Query: 136 LIVETME 142
L VE +E
Sbjct: 1545 LTVEAVE 1551
Score = 63.2 bits (152), Expect = 9e-11
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172
Score = 60.8 bits (146), Expect = 4e-10
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3338 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3396
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 152
D L I++ +D+ YT A N++G+ + TA L +E E E E+E
Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447
Score = 59.7 bits (143), Expect = 9e-10
Identities = 38/118 (32%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 19 SPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE 78
S L E + + + +F E E P P F K I D G+AA F C + G P P
Sbjct: 5488 SSLMEELVLKSNYTDSFFEFQVVEGP---PRFIKGISDCYAPIGTAAYFQCLVRGSPRPT 5544
Query: 79 VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 136
V W+KD + + + R F ++ G +L I+ + D+ +Y C A N G A A L
Sbjct: 5545 VYWYKDGKLV-QGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAAL 5601
Score = 58.9 bits (141), Expect = 2e-09
Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 2/129 (1%)
Query: 16 SPTSPLNAEKLESEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVVEGSAARFDCKIEGY 74
S ++ ++ K E ++ + F E ++P P F + I EV EG + F C +GY
Sbjct: 3911 SASTRIDEFKTEQKEENMRFFENSFRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGY 3970
Query: 75 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 134
P P V W+ +D I +++F I + + L +S V ++ TC N G T+
Sbjct: 3971 PQPIVTWYNNDMPIPRNQNF-IIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTS 4029
Query: 135 ELIVETMEE 143
L V+ ++
Sbjct: 4030 MLKVKAKQK 4038
Score = 58.9 bits (141), Expect = 2e-09
Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 14/130 (10%)
Query: 18 TSPLNAEKLESEDVSQA------FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKI 71
T L + + + V+Q+ FL + E P + K R EG + +C I
Sbjct: 4126 TEELEPKAMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHAR---CREGDSIILECLI 4182
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCGDDDAKYTCKAVNSLGE 129
G P P V WF++ +++++ FQ E+ NCS L I DV D KY C A N+ G
Sbjct: 4183 SGEPQPVVTWFQNGVLLKQNQKFQF---EEVNCSHQLYIKDVNSQDSGKYKCVAENNSGA 4239
Query: 130 ATCTAELIVE 139
++L VE
Sbjct: 4240 VESVSDLTVE 4249
Score = 58.5 bits (140), Expect = 2e-09
Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 26 LESEDV---SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWF 82
+ES DV + E A PYF ++VEG + F C++ G P P V W
Sbjct: 1057 VESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWK 1116
Query: 83 KDDQSIRESRHFQIDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
K + +++ Y+ + G C L+IS DD +YT N GE + +A L+ E
Sbjct: 1117 KSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEE 1174
Score = 57.4 bits (137), Expect = 5e-09
Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E+LE A ++K KP + V+EG ARF C++ GYP P+V W+
Sbjct: 1817 EELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL 1876
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
+ Q IR+S+ F++ Y DG L I D D + A N G +L ++ E+
Sbjct: 1877 NGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1934
Score = 57.4 bits (137), Expect = 5e-09
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 106
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3296
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Score = 54.3 bits (129), Expect = 4e-08
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 36 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 95
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1547 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1603
Query: 96 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 151
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1604 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1659
Score = 53.1 bits (126), Expect = 9e-08
Identities = 32/108 (29%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
EA+ + + P F + + +V E + F ++EG P P V W+++ + +I
Sbjct: 5172 EAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDE--RI 5229
Query: 97 DYDEDGN-CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
+ GN CSL IS++ + +Y C AVN +GEA A + + EE
Sbjct: 5230 KMERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEE 5277
Score = 50.1 bits (118), Expect = 8e-07
Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 45 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED--- 101
+ KP F++ + V+EG F C++ P PE+ WF +++ I I + D
Sbjct: 3501 YFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHH 3560
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
+ SL I V D Y A+NS G A TA L+V +++G+ E
Sbjct: 3561 HSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV--IQKGQDE 3604
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 98
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1754
Query: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+E G CSL D TC+A N G +A LIV+
Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1795
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3054 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ L+I D KYT A G TA+L VE
Sbjct: 3111 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3143
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 49 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 108
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2883 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2940
Query: 109 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 152
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2941 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2984
Score = 33.1 bits (74), Expect = 0.095
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 8/120 (6%)
Query: 21 LNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEV 79
+ A + E S AFL A++ F++ ++D+ E + A F+C+ P +V
Sbjct: 2151 VKAINIAGETSSHAFLLVQAKQLIT----FTQELQDVVAKEKDTMATFECETSE-PFVKV 2205
Query: 80 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
W+KD + E +++ D + L I + D Y+C V T TA+LIVE
Sbjct: 2206 KWYKDGMEVHEGDKYRMHSDRKVH-FLSILTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2263
Score = 32.7 bits (73), Expect = 0.12
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2362 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2419
Query: 114 DDDAKYTCKAVNSLGEAT 131
+D Y+ + +LG +T
Sbjct: 2420 EDAGNYSF-TIPALGLST 2436
Score = 30.8 bits (68), Expect = 0.47
Identities = 12/42 (28%), Positives = 23/42 (54%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 95
++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2492
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 80.1 bits (196), Expect = 7e-16
Identities = 40/116 (34%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E+L ED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+K
Sbjct: 1268 EELLEEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK 1326
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
D + I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1327 DGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382
Score = 75.5 bits (184), Expect = 2e-14
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E P P ++++ V+EG + +C I GYP P V W+++D I S FQI + +
Sbjct: 937 EIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QS 995
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
G L+I + +D ++TC AVN G + + L V+ EE E E
Sbjct: 996 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKE 1041
Score = 70.1 bits (170), Expect = 7e-13
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 105
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 67.8 bits (164), Expect = 3e-12
Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 21 LNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 80
L A + S A L AE P P F + ++ + V +GS R ++ G P P V
Sbjct: 80 LKATNGSGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 81 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
+++D I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+
Sbjct: 137 FYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Query: 141 MEE 143
EE
Sbjct: 196 EEE 198
Score = 65.9 bits (159), Expect = 1e-11
Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 15/113 (13%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P+F + ++ V G +A F+C + G +V W KD + IR +QI Y E+ + L
Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLEN-SAHLT 8211
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAEL--------------IVETMEEGEG 146
+ V D +YTC AVN +G+ +CTA+L + ET+EE EG
Sbjct: 8212 VLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEG 8264
Score = 65.5 bits (158), Expect = 2e-11
Identities = 35/94 (37%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
+ P+F+K +R+++ V R DCKI G V WFKD + I S ++I + E G S
Sbjct: 4111 IAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE-GTAS 4169
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L I V +D +TC+A NS+G + LIV+
Sbjct: 4170 LEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ 4203
Score = 63.5 bits (153), Expect = 7e-11
Identities = 44/127 (34%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 16 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 75
SP +LE D SQ LE + KP F + +EG ARFD K+ G P
Sbjct: 1433 SPARMSPGRRLEETDESQ--LERL------YKPVFVLKPVSFKCLEGQTARFDLKVVGRP 1484
Query: 76 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 135
PE WF D Q I ++ EDG SLII D ++T A N G ++ +
Sbjct: 1485 MPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVI 1544
Query: 136 LIVETME 142
L VE +E
Sbjct: 1545 LTVEAVE 1551
Score = 63.2 bits (152), Expect = 9e-11
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172
Score = 63.2 bits (152), Expect = 9e-11
Identities = 28/92 (30%), Positives = 54/92 (58%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
PYF + + +E V G A CK++G P+ + W+K+ +R + +++ + ++ SL+
Sbjct: 7020 PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQF-KNNVASLV 7078
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I+ V D +Y+CKA NS+G +A L+++
Sbjct: 7079 INKVDHSDVGEYSCKADNSVGAVASSAVLVIK 7110
Score = 62.8 bits (151), Expect = 1e-10
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
+ P F+K ++ ++ ++GS +C + G + WFKDDQ I S ++ + D
Sbjct: 4673 IPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSF-HDNTAF 4731
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L IS + G D YTC A N G C+ L V+
Sbjct: 4732 LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 4765
Score = 61.2 bits (147), Expect = 3e-10
Identities = 27/81 (33%), Positives = 51/81 (62%), Gaps = 1/81 (1%)
Query: 59 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 118
++ G +AR CK++G P +V WFK+++ + ES ++ Y + L I+DV +D
Sbjct: 3749 MLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRM-YFVNSEAILDITDVKVEDSGS 3807
Query: 119 YTCKAVNSLGEATCTAELIVE 139
Y+C+AVN +G +C+ E++++
Sbjct: 3808 YSCEAVNDVGSDSCSTEIVIK 3828
Score = 60.8 bits (146), Expect = 4e-10
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3338 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3396
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 152
D L I++ +D+ YT A N++G+ + TA L +E E E E+E
Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447
Score = 60.8 bits (146), Expect = 4e-10
Identities = 44/143 (30%), Positives = 61/143 (42%), Gaps = 21/143 (14%)
Query: 2 AMISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVE 61
A IS +S G + + +E VS + AV EE HVK
Sbjct: 31541 ARISCGGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVK-------------- 31586
Query: 62 GSAARFDCKIEGYPDP-EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
+ CKIE Y +V W+ + + S ++I Y EDG L + D+ DD Y
Sbjct: 31587 -----YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTYR 31640
Query: 121 CKAVNSLGEATCTAELIVETMEE 143
CK VN GE + AEL V+ + E
Sbjct: 31641 CKVVNDYGEDSSYAELFVKGVRE 31663
Score = 59.3 bits (142), Expect = 1e-09
Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
PYF K + ++V G +A C++ G P+ V W+K D +R + +++ + + +L+
Sbjct: 7961 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHF-RNNVATLV 8019
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ V +D +Y CKA NS+GE + + L V+
Sbjct: 8020 FNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051
Score = 58.5 bits (140), Expect = 2e-09
Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 26 LESEDV---SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWF 82
+ES DV + E A PYF ++VEG + F C++ G P P V W
Sbjct: 1057 VESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWK 1116
Query: 83 KDDQSIRESRHFQIDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
K + +++ Y+ + G C L+IS DD +YT N GE + +A L+ E
Sbjct: 1117 KSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEE 1174
Score = 57.8 bits (138), Expect = 4e-09
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P F++ +++ + GS+ +CK+ G P V WF + I R +Q D C+
Sbjct: 7680 VPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTL-TDNTCA 7738
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L ++ + D YTC A N G C+A L V
Sbjct: 7739 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 7771
Score = 57.8 bits (138), Expect = 4e-09
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 29 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 85
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 31773 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 31832
Query: 86 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 31833 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892
Query: 146 GEGEEEEE 153
E + +EE
Sbjct: 31893 QEFKSKEE 31900
Score = 57.4 bits (137), Expect = 5e-09
Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E+LE A ++K KP + V+EG ARF C++ GYP P+V W+
Sbjct: 1817 EELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL 1876
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
+ Q IR+S+ F++ Y DG L I D D + A N G +L ++ E+
Sbjct: 1877 NGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1934
Score = 57.4 bits (137), Expect = 5e-09
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 106
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3296
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Score = 57.4 bits (137), Expect = 5e-09
Identities = 40/127 (31%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
Query: 12 SSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKI 71
++ G +S N E + +E E + P + I LEV G A+F C+I
Sbjct: 3420 NAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEI 3479
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEAT 131
+ P+ WFK + I ES I + + SL I D +YTCKA N G +
Sbjct: 3480 QSAPNVRFQWFKAGREIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVS 3538
Query: 132 CTAELIV 138
CTA L V
Sbjct: 3539 CTATLTV 3545
Score = 57.4 bits (137), Expect = 5e-09
Identities = 28/93 (30%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Query: 48 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
P F K + +V +G + + +CKI G P+ +V WF++D + ES + + + + L
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF-INSVALL 6422
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I++ +D Y C+A N +G+A+C+ L V+
Sbjct: 6423 TINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455
Score = 57.4 bits (137), Expect = 5e-09
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F K +E ++G+ +C+++G P V W+KD + +R + ++I E+ S+
Sbjct: 7399 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MSENFLTSIH 7457
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I +V D +Y CKA N +G TC + ++
Sbjct: 7458 ILNVDAADIGEYQCKATNDVGSDTCVGSIALK 7489
Score = 57.0 bits (136), Expect = 6e-09
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
PYF + LE G + C++ G P+ V W+K D +R + ++ Y + +L+
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYR-TYFTNNVATLV 6137
Query: 108 ISDVCGDDDAKYTCKAVNSLGEAT 131
+ V +D +YTCKA NS+G A+
Sbjct: 6138 FNKVNINDSGEYTCKAENSIGTAS 6161
Score = 57.0 bits (136), Expect = 6e-09
Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
Query: 48 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
P F K + +V + R++CKI G P+ +V+W+KD+ I+ES F++ + D L
Sbjct: 7305 PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF-VDSVAVL 7363
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ ++ +D YTC+A N+ G A+ + L V+
Sbjct: 7364 EMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396
Score = 56.2 bits (134), Expect = 1e-08
Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F++ + ++GS C+I G P EVVW KD + +R S+ F+I + + SL
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKIT-SKHFDTSLH 6516
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 136
I ++ D +Y CKA N +G TC+ +
Sbjct: 6517 ILNLEASDVGEYHCKATNEVGSDTCSCSV 6545
Score = 56.2 bits (134), Expect = 1e-08
Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Query: 30 DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 89
+VS + V E+K + P FS+ +RD++ G FDC I G V W+KD + ++
Sbjct: 8041 EVSASTFLTVQEQK--LPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLK 8098
Query: 90 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+S + Q + D +L I +Y+C A N +G A+ +A LI+
Sbjct: 8099 DSPNVQTSF-LDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 8146
Score = 55.5 bits (132), Expect = 2e-08
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F + L G AA+F C + G P E +W KD ++ S +++I D + L
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRIS-DAENKHILE 3609
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+S++ D Y+CKA N G C AELI+
Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADICQAELII 3640
Score = 55.5 bits (132), Expect = 2e-08
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
+P P+F ++V+ G +A F+C + G + W KD++ IR ++ I G
Sbjct: 6266 EPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITC--VG 6323
Query: 103 NC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
N L I V D +YTC+A N +G+ C+A+L V+
Sbjct: 6324 NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVK 6361
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 44 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 102
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 30924 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 30983
Query: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
LII+ V DD Y +A N G + TA L VE
Sbjct: 30984 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 31020
Score = 55.5 bits (132), Expect = 2e-08
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 33192
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
I + D KYT KA N G+ + TA L+V + E
Sbjct: 33193 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 33228
Score = 55.1 bits (131), Expect = 2e-08
Identities = 29/95 (30%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 45 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 104
++ P F+K + ++ V GS+ +CK+ G WFKD + I S +++ E +
Sbjct: 5234 NIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHE-RSV 5292
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
SL ++++ +D A YTCK N G+ C+ L V+
Sbjct: 5293 SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327
Score = 55.1 bits (131), Expect = 2e-08
Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 1/85 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P FS +E ++ + +C++ G P EVVW+KD + +R S+ ++I ++ + S+
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKI-ASKNFHTSIH 5575
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATC 132
I +V D +Y CKA N +G TC
Sbjct: 5576 ILNVDTSDIGEYHCKAQNEVGSDTC 5600
Score = 54.3 bits (129), Expect = 4e-08
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 36 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 95
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1547 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1603
Query: 96 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 151
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1604 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1659
Score = 54.3 bits (129), Expect = 4e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 104
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 31748
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 31749 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 53.9 bits (128), Expect = 5e-08
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 32841 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 32900
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 32901 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 32950
Score = 53.5 bits (127), Expect = 7e-08
Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
PYF+K + +EV++ ++ G P E+ WFKD+ +R R ++ + +D SL
Sbjct: 4393 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYK-TFIQDHLVSLQ 4451
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 136
I D +Y C+ N +G + C+A +
Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARV 4480
Score = 53.5 bits (127), Expect = 7e-08
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 6/110 (5%)
Query: 36 LEAVAEEKPHVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
LE AE + +P F+K I+++ V E +A F+C++ + D V W+K + ES+ +
Sbjct: 8821 LETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEV-SFDDAIVTWYKGPTELTESQKY 8879
Query: 95 QIDYDEDGNCS-LIISDVCGDDDAKYTCKA-VNSLGEATCTAELIVETME 142
++ DG C + I +V DD+ Y+ A + GEA TAEL + T E
Sbjct: 8880 --NFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKE 8927
Score = 53.1 bits (126), Expect = 9e-08
Identities = 25/93 (26%), Positives = 54/93 (58%), Gaps = 2/93 (2%)
Query: 48 PYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
P F K + ++V+ G ++R +CKI G P+ VVWF+++ + S +++ + D +
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF-IDSVAVI 5481
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
++++ +D + C+A N G +C+ ++IV+
Sbjct: 5482 QMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514
Score = 53.1 bits (126), Expect = 9e-08
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 30592
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+++ +D+ YTC A N +GE +++L+++
Sbjct: 30593 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 30623
Score = 52.8 bits (125), Expect = 1e-07
Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
+G A + CK+ G P ++ WF +D+ I+ES ++ + E L ++DV +D +Y
Sbjct: 4313 KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVE-STAVLRLTDVGIEDSGEYM 4371
Query: 121 CKAVNSLGEATCTAELIVE 139
C+A N G C++ +IV+
Sbjct: 4372 CEAQNEAGSDHCSSIVIVK 4390
Score = 52.4 bits (124), Expect = 2e-07
Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F KT+ ++V G+ A C++ G E+ WFKD + IR S+ +++ + + L
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRL-FSQKSLVCLE 3889
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTA 134
I D +Y C N +G+ C A
Sbjct: 3890 IFSFNSADVGEYECVVANEVGKCGCMA 3916
Score = 52.4 bits (124), Expect = 2e-07
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F K I + V S+A F + G P + W KDDQ + E + I + D +L
Sbjct: 5048 PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISF-VDSVATLQ 5106
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I V +YTC+A N G C A L+V+
Sbjct: 5107 IRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138
Score = 51.6 bits (122), Expect = 3e-07
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
+ ++V E +C + G P+ +V W KD + I SR+F + + E+ S I V
Sbjct: 5148 KSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSF-ENNVASFRIQSVMKQ 5206
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
D +YT K N G ++C A L V
Sbjct: 5207 DSGQYTFKVENDFGSSSCDAYLRV 5230
Score = 51.6 bits (122), Expect = 3e-07
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
+ P F V+ G + D G P P V W KD+ ++++ + E+ N
Sbjct: 22146 IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTEN-NSL 22204
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I D C +D Y K NS GEA T +IV
Sbjct: 22205 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 22237
Score = 51.2 bits (121), Expect = 3e-07
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P F + ++D+ + G++ +C++ G V WF+D I Q + E+ C+
Sbjct: 6739 VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCT 6797
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L +S + D YTC A N G C+A L V+
Sbjct: 6798 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 6831
Score = 51.2 bits (121), Expect = 3e-07
Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 106
P F K + D+ V G + IEG VVWFKD + +RES + I Y E+ +L
Sbjct: 7492 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSEN-IATL 7550
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
S V + KYTC+ N G C A L V
Sbjct: 7551 QFSRVEPANAGKYTCQIKNDAGMQECFATLSV 7582
Score = 50.8 bits (120), Expect = 4e-07
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P F++ +++ V G++ +CK+ G V WF + I +Q + D C+
Sbjct: 5798 VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF-SDNVCT 5856
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L ++ + D YTC A N G C A L V+
Sbjct: 5857 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQ 5890
Score = 50.4 bits (119), Expect = 6e-07
Identities = 31/92 (33%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F K + DL + G + G V W K + IRE ++ + +G LI
Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGVAVLI 3982
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I DV KYTC A N G T ELIV+
Sbjct: 3983 IPDVQISFGGKYTCLAENEAGSQTSVGELIVK 4014
Score = 50.4 bits (119), Expect = 6e-07
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 32 SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 91
S A L A + P P+F++ ++D+ G F+C+I G +V W+KD +++
Sbjct: 7103 SSAVLVIKARKLP---PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDD 7159
Query: 92 RHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
+ Q + + +L I +Y C A N LG A+ +A+LI+ E
Sbjct: 7160 ANLQTSFVHN-VATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 7209
Score = 49.7 bits (117), Expect = 1e-06
Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P+F +++ G + F C + G ++ W KD++ IR ++++ E+ +
Sbjct: 7210 VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVEN-TAT 7268
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L + V D +YTC A N G+ +C+A+L V+
Sbjct: 7269 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 7302
Score = 49.3 bits (116), Expect = 1e-06
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F K I + G A F ++G V W KD I E + ++ + E+ SL
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF-ENNVASLY 4544
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+S + D KY C+A N G C+A L V+
Sbjct: 4545 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK 4576
Score = 49.3 bits (116), Expect = 1e-06
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
E K P F + ++ +EVV+ S +C++ G P EV W K+++ IR S+ + + D
Sbjct: 4948 ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLT-DR 5006
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+L I+ D +Y C N G +C+ + ++
Sbjct: 5007 VSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK 5045
Score = 48.5 bits (114), Expect = 2e-06
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 10/105 (9%)
Query: 19 SPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 77
SP + +E V + A + +K SK I L VVE S R
Sbjct: 32697 SPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK--------- 32747
Query: 78 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCK 122
EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C+
Sbjct: 32748 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCE 32792
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 98
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1754
Query: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+E G CSL D TC+A N G +A LIV+
Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1795
Score = 47.8 bits (112), Expect = 4e-06
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F K LEV+ G F I G P +V WF+ + + + I Y ED L
Sbjct: 5893 PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNI-YFEDTVAELE 5951
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ ++ +YTC N+ G+A+CT L V+
Sbjct: 5952 LFNIDISQSGEYTCVVSNNAGQASCTTRLFVK 5983
Score = 47.4 bits (111), Expect = 5e-06
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
++ + P F++ ++D+E G C++ G +V W++D +R+ + Q + D
Sbjct: 6169 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSF-VD 6227
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 136
+L I +Y+C A N LG A+ +A L
Sbjct: 6228 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 6262
Score = 47.0 bits (110), Expect = 6e-06
Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 1/115 (0%)
Query: 25 KLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD 84
K+ ++ S ++ ++P P F + + + V EG + C ++G + W K
Sbjct: 8323 KVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKA 8382
Query: 85 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ I+ S + G L + DV D Y CKA N G T +++ ++
Sbjct: 8383 GREIKPSDRCSFSF-ASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 8436
Score = 47.0 bits (110), Expect = 6e-06
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
E P + + + L + G + R ++G P P V WFKD I + + +I D
Sbjct: 27952 ENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DV 28010
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 28011 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049
Score = 46.6 bits (109), Expect = 8e-06
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 11/128 (8%)
Query: 21 LNAEKLESEDVSQAFLEAVAEE---------KPHVKPYFSKTIRDLEVVEGSAARFDCKI 71
L+ LE+ DV + +A E K P F K + D + G A +
Sbjct: 6515 LHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIV 6574
Query: 72 EGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 130
EG+ VVW KD + IRES + +I + D +L + + KY C+ N G
Sbjct: 6575 EGFQPISVVWLKDRGEVIRESENTRISF-IDNIATLQLGSPEASNSGKYICQIKNDAGMR 6633
Query: 131 TCTAELIV 138
C+A L V
Sbjct: 6634 ECSAVLTV 6641
Score = 46.2 bits (108), Expect = 1e-05
Identities = 34/114 (29%), Positives = 51/114 (44%), Gaps = 6/114 (5%)
Query: 28 SEDVSQAFLEAV--AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 85
S DV A +A +E P + K L + G + F+C+I G P V W+ D
Sbjct: 4843 SNDVGTATSKATLFVKEPPQ---FIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDG 4899
Query: 86 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I + I + DG + IS ++ Y C+A N G A+C+ EL V+
Sbjct: 4900 NEITAIQKHGISFI-DGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 4952
Score = 46.2 bits (108), Expect = 1e-05
Identities = 23/95 (24%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 46 VKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 104
+ P F+K + + +E EG++ + + ++ G V W+K++ I+ + + +I + ++
Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF-KNNTL 8305
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L + +D YTCK N G A CT+ ++++
Sbjct: 8306 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 8340
Score = 45.8 bits (107), Expect = 1e-05
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 44 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 103
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 12372 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 12427
Query: 104 CSLIISDVCGDDDAKYTCK 122
L+I+ DD+A+Y+C+
Sbjct: 12428 RILVINKCLLDDEAEYSCE 12446
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3054 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ L+I D KYT A G TA+L VE
Sbjct: 3111 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3143
Score = 45.4 bits (106), Expect = 2e-05
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F +T +EV+ G + F I G P +V WFK + + I ED L
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISL-EDFVTELE 6892
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ +V + Y+C N G A+CT L V+
Sbjct: 6893 LFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924
Score = 43.9 bits (102), Expect = 5e-05
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
+ V G +CK+ G P+ V W+KD + + S+ + + + SL I V D
Sbjct: 5713 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLRILSVERQDA 5771
Query: 117 AKYTCKAVNSLGEATCTA 134
YT + N++G+++CTA
Sbjct: 5772 GTYTFQVQNNVGKSSCTA 5789
Score = 43.9 bits (102), Expect = 5e-05
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
++V G +C + G P+ WFKD + + ++I + + L I +V D
Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS-GLKIINVAPSDS 7653
Query: 117 AKYTCKAVNSLGEATCTAELIV 138
Y+ + N +G+ +CTA L V
Sbjct: 7654 GVYSFEVQNPVGKDSCTASLQV 7675
Score = 43.9 bits (102), Expect = 5e-05
Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F + ++V+ G+ F ++G P V WFK + + ED L
Sbjct: 7775 PSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSL-EDSVAELE 7833
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ DV +YTC N G+A+CT L ++
Sbjct: 7834 LFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 7865
Score = 43.9 bits (102), Expect = 5e-05
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R + V EG +ARF C +G P P V W + Q + S Q+ + + IS V
Sbjct: 32568 RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK-YKSTFEISSVQAS 32626
Query: 115 DDAKYTCKAVNSLGEATCTAELIVE 139
D+ Y+ NS G+ L ++
Sbjct: 32627 DEGNYSVVVENSEGKQEAEFTLTIQ 32651
Score = 43.5 bits (101), Expect = 7e-05
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
KP+F K + ++ +C+++ V W KD Q + + ++I + ED +L
Sbjct: 3643 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICF-EDKIATL 3701
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
I D Y C A N G ++C+A + V
Sbjct: 3702 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 3733
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 49 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 108
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2883 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2940
Query: 109 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 152
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2941 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2984
Score = 43.1 bits (100), Expect = 9e-05
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 109
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 16126 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 16184
Query: 110 DVCGDDDAKYTCKAVNSLGEAT 131
D YT AVN+LG A+
Sbjct: 16185 QSRRSDTGLYTITAVNNLGTAS 16206
Score = 43.1 bits (100), Expect = 9e-05
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 18888 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 18947
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 18948 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988
Score = 42.7 bits (99), Expect = 1e-04
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 50 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 103
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 11117 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 11174
Query: 104 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
+I DV D +YTC E T TA+L+VE +
Sbjct: 11175 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210
Score = 42.4 bits (98), Expect = 2e-04
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 23229 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 23283
Query: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 137
+L I + DD +Y N +G+ T + E++
Sbjct: 23284 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 23318
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 12522
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 152
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 12523 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 12570
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/127 (22%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 12 SSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKI 71
S PT + A +++++ + FL+ K + L V G+ +
Sbjct: 13670 SKPSRPTEEIQA--VDTQEAPEIFLDV-------------KLLAGLTVKAGTKIELPATV 13714
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEAT 131
G P+P++ W K D +++ + I+ + ++ I D D Y +AVN G AT
Sbjct: 13715 TGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRAT 13773
Query: 132 CTAELIV 138
E+ V
Sbjct: 13774 AVVEVNV 13780
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 103
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 33385
Query: 104 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
+LII DV D YT N G + T + + ++
Sbjct: 33386 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 33423
Score = 41.2 bits (95), Expect = 3e-04
Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 18 TSPLNAEKLESEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKI 71
T + + L +D SQ +EA+ +E K V PYF+ ++D VE C+I
Sbjct: 11982 THSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEI 12041
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
D V WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 12042 SK-ADAPVKWFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 12089
Score = 41.2 bits (95), Expect = 3e-04
Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 16/131 (12%)
Query: 7 LSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPY--------------FSK 52
L G+K P + K+ + + LE E + K + F+K
Sbjct: 12230 LKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTK 12289
Query: 53 TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
+ D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I D
Sbjct: 12290 PLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIHDCT 12347
Query: 113 GDDDAKYTCKA 123
+D YTC A
Sbjct: 12348 PEDIKTYTCDA 12358
Score = 41.2 bits (95), Expect = 3e-04
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 17515 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 17573
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIV 138
D +Y N+ G T L V
Sbjct: 17574 LRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 40.8 bits (94), Expect = 5e-04
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F K + D V GS + G P V W KD+ I +S I E I+
Sbjct: 6929 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 6988
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
+D A+Y+C N G+ C E +V +E
Sbjct: 6989 STI-EDYAQYSCLIENEAGQDIC--EALVSVLE 7018
Score = 40.8 bits (94), Expect = 5e-04
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G + + D I G P P + W K DQ + + +I D SL + D D Y
Sbjct: 22558 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYIL 22616
Query: 122 KAVNSLGEATCTAELIV 138
KA N GE + T + V
Sbjct: 22617 KAKNVAGERSVTVNVKV 22633
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 24310 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 24368
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I + DD KYT A NS G AT +IV
Sbjct: 24369 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401
Score = 39.7 bits (91), Expect = 0.001
Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 9/124 (7%)
Query: 22 NAEKLESEDVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPE 78
+ K+ + D S + +A+E+ +P F S+ + L V G++ G P P
Sbjct: 26159 SVNKVGASDPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPN 26217
Query: 79 VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
V+W K D +R + D SL I + +D KYT N L A+ T L+V
Sbjct: 26218 VLWSKPDTDLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVV 26272
Query: 139 ETME 142
+ ++
Sbjct: 26273 KVLD 26276
Score = 39.3 bits (90), Expect = 0.001
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 14376 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 14435
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
D + L + D YT N LG AT + + V
Sbjct: 14436 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 14476
Score = 38.9 bits (89), Expect = 0.002
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
++V +G A K G + WFKD Q + ++I + + IIS D
Sbjct: 4588 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTE-KKDS 4646
Query: 117 AKYTCKAVNSLGEATCTAELIV 138
+YT + N +G ++C A + V
Sbjct: 4647 GEYTFEVQNDVGRSSCKARINV 4668
Score = 38.9 bits (89), Expect = 0.002
Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 1/81 (1%)
Query: 58 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 117
+ + S F ++G P ++ WFKDD + I E L + V
Sbjct: 5340 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGL-EGSTSFLNLYSVDASKTG 5398
Query: 118 KYTCKAVNSLGEATCTAELIV 138
+YTC N +G +CT L+V
Sbjct: 5399 QYTCHVTNDVGSDSCTTMLLV 5419
Score = 38.9 bits (89), Expect = 0.002
Identities = 36/141 (25%), Positives = 48/141 (34%), Gaps = 29/141 (20%)
Query: 41 EEKPHVKP-----------YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 89
++KP V P +F + + VVE + A F K+ G P P V W K
Sbjct: 8436 KDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL 8495
Query: 90 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE---- 145
+ + L I D D Y C A N GE L V+ ++ E
Sbjct: 8496 NQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEG 8555
Query: 146 --------------GEGEEEE 152
G GEEEE
Sbjct: 8556 DLRAMLKKTPILKKGAGEEEE 8576
Score = 38.5 bits (88), Expect = 0.002
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 23632 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 23690
Query: 114 DDDAKYTCKAVNSLG 128
D +Y +A N G
Sbjct: 23691 IDGGQYILRASNVAG 23705
Score = 38.1 bits (87), Expect = 0.003
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
PYF + + +V + + + G + WFKD++ + + + +D + SL
Sbjct: 4768 PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSV-WKDDTSTSLE 4826
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ D Y C+ N +G AT A L V+
Sbjct: 4827 LFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858
Score = 37.4 bits (85), Expect = 0.005
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 115
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 15170
Query: 116 DAKYTCKAVNSLGEATCTAELIV 138
+Y A NS G A + V
Sbjct: 15171 HGRYVITATNSCGSKFAAARVEV 15193
Score = 37.0 bits (84), Expect = 0.007
Identities = 27/127 (21%), Positives = 56/127 (44%), Gaps = 9/127 (7%)
Query: 12 SSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKI 71
S +G T ++ E ++ + +++A A+ F K + D + +G +
Sbjct: 7840 SQSGEYTCIVSNEAGKASCTTHLYIKAPAK--------FVKRLNDYSIEKGKPLILEGTF 7891
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEAT 131
G P V W K+ ++ S+ I E + L I +D +Y C N+ G+ +
Sbjct: 7892 TGTPPISVTWKKNGINVTPSQRCNITTTEK-SAILEIPSSTVEDAGQYNCYIENASGKDS 7950
Query: 132 CTAELIV 138
C+A++++
Sbjct: 7951 CSAQILI 7957
Score = 37.0 bits (84), Expect = 0.007
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 109
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 17913 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 17969
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTA 134
+ D KY A NS G A +A
Sbjct: 17970 EAVRADHGKYIISAKNSSGHAQGSA 17994
Score = 37.0 bits (84), Expect = 0.007
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 39 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 92
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 18187 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 18246
Query: 93 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
++ D + S ++ D KY A N+ G A + V
Sbjct: 18247 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 23008
Query: 117 AKYTCKAVNSLG 128
KYT NS G
Sbjct: 23009 GKYTLTLENSSG 23020
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 48 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 104
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 26928
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCT 133
S++I D + Y K N++G A+ T
Sbjct: 26929 SILIKDADRLNSGCYELKLRNAMGSASAT 26957
Score = 36.6 bits (83), Expect = 0.009
Identities = 17/77 (22%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
++P + + ++D+ + EG C+ P+ + WF++ + ++ + + + +
Sbjct: 8743 IEPAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRILKPQGRHKTEVEHKVH-K 8800
Query: 106 LIISDVCGDDDAKYTCK 122
L I+DV +D +YTCK
Sbjct: 8801 LTIADVRAEDQGQYTCK 8817
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 33 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 89
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 28631 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 28689
Query: 90 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 28690 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 28737
Score = 35.8 bits (81), Expect = 0.015
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 106
P F + L VV G A IEG V W K+ ++ IRES + +I + E+ +L
Sbjct: 5610 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN-VATL 5668
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ + KY C+ N G A L+V
Sbjct: 5669 QFAKAEPANAGKYICQIKNDGGMRENMATLMV 5700
Score = 35.8 bits (81), Expect = 0.015
Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDD 115
+ V G+ +C + G P+ WFKD + + +S+H ++ + + +++ D
Sbjct: 6654 MTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEM--SD 6711
Query: 116 DAKYTCKAVNSLGEATCTAELIV 138
Y+ + NS+G++ CT + V
Sbjct: 6712 KGLYSFEVKNSVGKSNCTVSVHV 6734
Score = 35.8 bits (81), Expect = 0.015
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 129
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 27296 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 27352
Score = 35.4 bits (80), Expect = 0.019
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 106
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 32374 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 32431
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
I D DD Y N GEA+ A L V
Sbjct: 32432 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463
Score = 35.0 bits (79), Expect = 0.025
Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 9/129 (6%)
Query: 13 STGSPTSPLNAEKLESEDVSQAF-----LEAVAEEKP-HVKPYFSKTIRDLEVVEGSAAR 66
S+ T L +++ +D+SQ L + A+ K PYF+ + D VE
Sbjct: 11622 SSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEIT 11681
Query: 67 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 126
C++ D V WFKD + I S + I D L I D +Y C
Sbjct: 11682 LKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYVCDCGTD 11738
Query: 127 LGEATCTAE 135
+A T E
Sbjct: 11739 KTKANVTVE 11747
Score = 35.0 bits (79), Expect = 0.025
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 11842 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 11899
Query: 110 DVCGDDDAKYTCKA 123
+D+AKY +A
Sbjct: 11900 SAAFEDEAKYMFEA 11913
Score = 35.0 bits (79), Expect = 0.025
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 19363
Query: 117 AKYTCKAVNSLGEATCTAELIV 138
YT A NS G + T +L V
Sbjct: 19364 GDYTITAENSSGSKSATIKLKV 19385
Score = 34.7 bits (78), Expect = 0.033
Identities = 18/82 (21%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
++V G A + + G P+ + W+KD + + S+ ++I + ++ L D
Sbjct: 4026 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDS 4084
Query: 117 AKYTCKAVNSLGEATCTAELIV 138
+YT + N +G ++C V
Sbjct: 4085 GQYTFEISNEVGSSSCETTFTV 4106
Score = 34.7 bits (78), Expect = 0.033
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 25393 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 25451
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I + +D Y NS G T +IV
Sbjct: 25452 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 25484
Score = 34.3 bits (77), Expect = 0.043
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 12646 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 12703
Query: 114 DDDAKYTCKAVNSLGE-ATCTAELIVE 139
DD A Y N GE A LIVE
Sbjct: 12704 DDQANYNVSLTNHRGENVKSAANLIVE 12730
Score = 34.3 bits (77), Expect = 0.043
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 51 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 110
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 24028 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 24083
Query: 111 VCGDDDA-KYTCKAVNSLG 128
C +DA KY K NS G
Sbjct: 24084 NCDRNDAGKYILKLENSSG 24102
Score = 33.9 bits (76), Expect = 0.056
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 1/82 (1%)
Query: 58 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 117
+V+ GSA +G + WFK ++ + I E SL + V D
Sbjct: 4216 DVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYIT-KEALESSLELYLVKTSDSG 4274
Query: 118 KYTCKAVNSLGEATCTAELIVE 139
YTCK N G C+A L V+
Sbjct: 4275 TYTCKVSNVAGGVECSANLFVK 4296
Score = 33.9 bits (76), Expect = 0.056
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 21534
Query: 122 KAVNSLGEA 130
A N G A
Sbjct: 21535 TATNPGGFA 21543
Score = 33.9 bits (76), Expect = 0.056
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 84
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 29428 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 29482
Query: 85 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 133
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 29483 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 29529
Score = 33.5 bits (75), Expect = 0.073
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 11576 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 11633
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+V DD ++ + + E + TA+L V
Sbjct: 11634 EVTLDDISQIKAQ----VKELSSTAQLKV 11658
Score = 33.5 bits (75), Expect = 0.073
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 11931 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 11988
Query: 110 DVCGDDDAKYTCKAVNSLGEATCT 133
D+ DD ++ +A+ EA T
Sbjct: 11989 DLSIDDTSQIRVEAMGMSSEAKLT 12012
Score = 33.1 bits (74), Expect = 0.095
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 8/120 (6%)
Query: 21 LNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEV 79
+ A + E S AFL A++ F++ ++D+ E + A F+C+ P +V
Sbjct: 2151 VKAINIAGETSSHAFLLVQAKQLIT----FTQELQDVVAKEKDTMATFECETSE-PFVKV 2205
Query: 80 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
W+KD + E +++ D + L I + D Y+C V T TA+LIVE
Sbjct: 2206 KWYKDGMEVHEGDKYRMHSDRKVH-FLSILTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2263
Score = 33.1 bits (74), Expect = 0.095
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 17282
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
D Y+ N G T + +++V
Sbjct: 17283 DGGIYSLTVENPAGSKTVSVKVLV 17306
Score = 32.7 bits (73), Expect = 0.12
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2362 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2419
Query: 114 DDDAKYTCKAVNSLGEAT 131
+D Y+ + +LG +T
Sbjct: 2420 EDAGNYSF-TIPALGLST 2436
Score = 32.7 bits (73), Expect = 0.12
Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F K + D V G + + G V W KD +I S I E C L I
Sbjct: 5988 FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEK-TCILEIL 6046
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
+ D +Y+C+ N G C A +V T+E
Sbjct: 6047 NSTKRDAGQYSCEIENEAGRDVCGA--LVSTLE 6077
Score = 32.7 bits (73), Expect = 0.12
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 120
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 29062 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 29119
Query: 121 CKAVNSLG 128
N+ G
Sbjct: 29120 LTVKNASG 29127
Score = 32.3 bits (72), Expect = 0.16
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 55 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 12559 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 12614
Query: 113 GDDDAKYTCKAVNSLGEATCTAELIV 138
D Y V +G A A L V
Sbjct: 12615 LQDMGTY----VVMVGAARAAAHLTV 12636
Score = 32.3 bits (72), Expect = 0.16
Identities = 27/111 (24%), Positives = 36/111 (32%), Gaps = 30/111 (27%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQ--------------------SIRESRHF-- 94
LEV G D I G P P + W KD+ ++E F
Sbjct: 14689 LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVL 14748
Query: 95 ------QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATCTAELI 137
ID + G L + D D Y K N G +A CT ++
Sbjct: 14749 PLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 14799
Score = 32.0 bits (71), Expect = 0.21
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 109
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 18611 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 18666
Query: 110 DVCGDDDAKYTCKAVNSLGE 129
+ DD KY+ VN GE
Sbjct: 18667 NSTRDDSGKYSLTLVNPAGE 18686
Score = 32.0 bits (71), Expect = 0.21
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773
Query: 114 DDDAKYTCKAVN 125
D +Y K N
Sbjct: 24774 TDGGQYILKLSN 24785
Score = 31.6 bits (70), Expect = 0.28
Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 11 KSSTGSPTSPLNAEKLE-SEDVSQAFLEAVAEEKPHVKPYFSKT-IRDLE---VVEGSAA 65
K S T L E++E SE + F E V+ + + T I+D+E V++ + A
Sbjct: 8614 KQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDA 8673
Query: 66 RFDCKIE-GYPDPEVVWFKDDQSIRESRHFQIDYDED 101
F+ I+ YP+ ++ W+K + + S F+I D D
Sbjct: 8674 VFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGD 8710
Score = 31.6 bits (70), Expect = 0.28
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 19996 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 20054
Query: 121 CKAVNSLG--EATCTAELI 137
N G E T + +++
Sbjct: 20055 ITLKNVAGTKEGTISIKVV 20073
Score = 31.2 bits (69), Expect = 0.36
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 20840
Query: 115 DDAKYTCKAVNSLGE 129
D K+ N G+
Sbjct: 20841 DTGKFVMTIENPAGK 20855
Score = 31.2 bits (69), Expect = 0.36
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 120
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 21137
Query: 121 CKAVNSLGE 129
A N +GE
Sbjct: 21138 LTARNIVGE 21146
Score = 31.2 bits (69), Expect = 0.36
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 25796 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 25854
Query: 114 DDDAKYTCKAVNSLG 128
D +Y N G
Sbjct: 25855 RDTGQYVLTLKNVAG 25869
Score = 31.2 bits (69), Expect = 0.36
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 120
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 28372 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 28427
Query: 121 CKAVNSLGEATCT 133
N+ G + T
Sbjct: 28428 LTVENNSGSKSIT 28440
Score = 31.2 bits (69), Expect = 0.36
Identities = 26/104 (25%), Positives = 36/104 (34%), Gaps = 3/104 (2%)
Query: 38 AVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
A E + K + KT+ + V G G PDP + W K I + H+
Sbjct: 31015 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 31074
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Q+ + + V D Y A N G T EL V
Sbjct: 31075 QVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 31118
Score = 30.8 bits (68), Expect = 0.47
Identities = 12/42 (28%), Positives = 23/42 (54%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 95
++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2492
Score = 30.8 bits (68), Expect = 0.47
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYD 99
E P +K S ++V G + G P P++ W K++ I + + QI +
Sbjct: 15392 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 15451
Query: 100 E----DGNCSLIISDVCGDDDAKYTCKAVNSLG 128
E + L I +D YT A N LG
Sbjct: 15452 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 15484
Score = 30.8 bits (68), Expect = 0.47
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 54 IRDLEVVEGSAA-RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
+R + V+ SA R I+G P+PEV W K + + + ++ L+I +V
Sbjct: 25113 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEV---TSSFTMLVIDNVT 25169
Query: 113 GDDDAKYTCKAVNSLGEAT 131
D +Y N+ G T
Sbjct: 25170 RFDSGRYNLTLENNSGSKT 25188
Score = 30.4 bits (67), Expect = 0.62
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG------NCSLIISDVC-GD 114
GS R I+G P P+ W D ++ + + D ED N S+II C
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
KY+ A N G+ T + V
Sbjct: 15885 HTGKYSITAKNKAGQKTANCRVKV 15908
Score = 30.0 bits (66), Expect = 0.81
Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
GS + D I G P P+V +D ++ + F + + N ++ + + D +Y
Sbjct: 26491 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESVTADAGRYEI 26549
Query: 122 KAVNSLGEATCTAELIV 138
A NS G ++V
Sbjct: 26550 TAANSSGTTKAFINIVV 26566
Score = 29.6 bits (65), Expect = 1.1
Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 1/84 (1%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
+ + V G I G P P WF +RES ++ L I +
Sbjct: 29746 KTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVE-THTKVAKLTIRETTIR 29804
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
D +YT + N G + T ++I+
Sbjct: 29805 DTGEYTLELKNVTGTTSETIKVII 29828
Score = 28.1 bits (61), Expect = 3.1
Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 91
+ ++D+ V G A FDC++ Y D V W+ + + S
Sbjct: 12200 RPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPS 12238
Score = 28.1 bits (61), Expect = 3.1
Identities = 20/72 (27%), Positives = 26/72 (36%), Gaps = 1/72 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
L + G A + G P P+V WFKD+ + E I +L D
Sbjct: 16828 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK-TTPATLALEKIKAKRSDS 16886
Query: 117 AKYTCKAVNSLG 128
KY NS G
Sbjct: 16887 GKYCVVVENSTG 16898
Score = 28.1 bits (61), Expect = 3.1
Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
G + +G P P + W KD ++ES + E+ +L I + + KYT
Sbjct: 27578 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTEN-KITLSIKNAKKEHGGKYT 27635
Score = 27.7 bits (60), Expect = 4.0
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G R ++G P P++ W K + ++R+ I D + L +V D KY
Sbjct: 19708 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVNKYDAGKYIL 19766
Query: 122 KAVNSLGEATCTAELIVETME 142
NS G+ T ++V+ ++
Sbjct: 19767 TLENSCGKKEYT--IVVKVLD 19785
Score = 26.6 bits (57), Expect = 8.9
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
++RD VV G R + G P P V W +++++ + + + S++I +
Sbjct: 16529 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAI---SSSMVIKNC 16585
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIVETME 142
Y+ A N GE T +IV+ ++
Sbjct: 16586 QRSHQGVYSLLAKNEAGERKKT--IIVDVLD 16614
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 80.1 bits (196), Expect = 7e-16
Identities = 40/116 (34%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E+L ED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+K
Sbjct: 1222 EELLEEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK 1280
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
D + I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1281 DGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 75.5 bits (184), Expect = 2e-14
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E P P ++++ V+EG + +C I GYP P V W+++D I S FQI + +
Sbjct: 891 EIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QS 949
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
G L+I + +D ++TC AVN G + + L V+ EE E E
Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKE 995
Score = 73.9 bits (180), Expect = 5e-14
Identities = 38/112 (33%), Positives = 63/112 (56%), Gaps = 3/112 (2%)
Query: 27 ESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 86
E+E LE + P P+F K ++ + +G A F+ + G P P V WFK+++
Sbjct: 3749 ETESAVAKSLEKLGGPCP---PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENK 3805
Query: 87 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ S ++ I ++ +G+ + I++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3806 QLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 70.1 bits (170), Expect = 7e-13
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 105
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 67.8 bits (164), Expect = 3e-12
Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 21 LNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 80
L A + S A L AE P P F + ++ + V +GS R ++ G P P V
Sbjct: 80 LKATNGSGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 81 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
+++D I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+
Sbjct: 137 FYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Query: 141 MEE 143
EE
Sbjct: 196 EEE 198
Score = 63.5 bits (153), Expect = 7e-11
Identities = 44/127 (34%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 16 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 75
SP +LE D SQ LE + KP F + +EG ARFD K+ G P
Sbjct: 1387 SPARMSPGRRLEETDESQ--LERL------YKPVFVLKPVSFKCLEGQTARFDLKVVGRP 1438
Query: 76 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 135
PE WF D Q I ++ EDG SLII D ++T A N G ++ +
Sbjct: 1439 MPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVI 1498
Query: 136 LIVETME 142
L VE +E
Sbjct: 1499 LTVEAVE 1505
Score = 63.2 bits (152), Expect = 9e-11
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 61.2 bits (147), Expect = 3e-10
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E LE S + EK P F K + + ++ G A + G P P++ WF
Sbjct: 3625 ETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFF 3684
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
+ + S ++ +D D + SLII +D+ +YTC A N G+ C+A L + + E
Sbjct: 3685 NGVLLTPSADYKFVFDGDDH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGE 3743
Query: 144 GEGEGEEE 151
G + E E
Sbjct: 3744 GHKDTETE 3751
Score = 60.8 bits (146), Expect = 4e-10
Identities = 44/143 (30%), Positives = 61/143 (42%), Gaps = 21/143 (14%)
Query: 2 AMISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVE 61
A IS +S G + + +E VS + AV EE HVK
Sbjct: 25236 ARISCGGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVK-------------- 25281
Query: 62 GSAARFDCKIEGYPDP-EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
+ CKIE Y +V W+ + + S ++I Y EDG L + D+ DD Y
Sbjct: 25282 -----YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTYR 25335
Query: 121 CKAVNSLGEATCTAELIVETMEE 143
CK VN GE + AEL V+ + E
Sbjct: 25336 CKVVNDYGEDSSYAELFVKGVRE 25358
Score = 58.9 bits (141), Expect = 2e-09
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME-EGEGEGEEEEE 153
D L I++ +D+ YT A N++G+ + TA L +E + + G++ E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRE 3403
Score = 58.5 bits (140), Expect = 2e-09
Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 26 LESEDV---SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWF 82
+ES DV + E A PYF ++VEG + F C++ G P P V W
Sbjct: 1011 VESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWK 1070
Query: 83 KDDQSIRESRHFQIDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
K + +++ Y+ + G C L+IS DD +YT N GE + +A L+ E
Sbjct: 1071 KSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 4e-09
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 29 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 85
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25468 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25527
Query: 86 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25528 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587
Query: 146 GEGEEEEE 153
E + +EE
Sbjct: 25588 QEFKSKEE 25595
Score = 57.4 bits (137), Expect = 5e-09
Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E+LE A ++K KP + V+EG ARF C++ GYP P+V W+
Sbjct: 1771 EELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL 1830
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
+ Q IR+S+ F++ Y DG L I D D + A N G +L ++ E+
Sbjct: 1831 NGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888
Score = 57.4 bits (137), Expect = 5e-09
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 106
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 44 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 102
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24619 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24678
Query: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
LII+ V DD Y +A N G + TA L VE
Sbjct: 24679 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24715
Score = 55.5 bits (132), Expect = 2e-08
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26887
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26888 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26923
Score = 54.3 bits (129), Expect = 4e-08
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 36 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 95
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 96 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 151
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 4e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 104
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25443
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25444 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 53.9 bits (128), Expect = 5e-08
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26536 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26595
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26596 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26645
Score = 53.5 bits (127), Expect = 7e-08
Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P + I LEV G A+F C+I+ P+ WFK + I ES I + + SL
Sbjct: 4529 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS-SLE 4587
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4588 ILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4624
Score = 53.1 bits (126), Expect = 9e-08
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24287
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24288 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24318
Score = 51.6 bits (122), Expect = 3e-07
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
+ P F V+ G + D G P P V W KD+ ++++ + E+ N
Sbjct: 15841 IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTEN-NSL 15899
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I D C +D Y K NS GEA T +IV
Sbjct: 15900 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15932
Score = 48.5 bits (114), Expect = 2e-06
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 10/105 (9%)
Query: 19 SPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 77
SP + +E V + A + +K SK I L VVE S R
Sbjct: 26392 SPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK--------- 26442
Query: 78 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCK 122
EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C+
Sbjct: 26443 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCE 26487
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 98
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.0 bits (110), Expect = 6e-06
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
E P + + + L + G + R ++G P P V WFKD I + + +I D
Sbjct: 21647 ENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DV 21705
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21706 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744
Score = 45.8 bits (107), Expect = 1e-05
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 44 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 103
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 6067 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6122
Query: 104 CSLIISDVCGDDDAKYTCK 122
L+I+ DD+A+Y+C+
Sbjct: 6123 RILVINKCLLDDEAEYSCE 6141
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 43.9 bits (102), Expect = 5e-05
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R + V EG +ARF C +G P P V W + Q + S Q+ + + IS V
Sbjct: 26263 RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK-YKSTFEISSVQAS 26321
Query: 115 DDAKYTCKAVNSLGEATCTAELIVE 139
D+ Y+ NS G+ L ++
Sbjct: 26322 DEGNYSVVVENSEGKQEAEFTLTIQ 26346
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 49 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 108
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 109 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 152
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 9e-05
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 109
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9821 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9879
Query: 110 DVCGDDDAKYTCKAVNSLGEAT 131
D YT AVN+LG A+
Sbjct: 9880 QSRRSDTGLYTITAVNNLGTAS 9901
Score = 43.1 bits (100), Expect = 9e-05
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12583 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12642
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12643 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683
Score = 42.7 bits (99), Expect = 1e-04
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 50 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 103
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4812 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4869
Query: 104 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
+I DV D +YTC E T TA+L+VE +
Sbjct: 4870 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905
Score = 42.4 bits (98), Expect = 2e-04
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16924 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16978
Query: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 137
+L I + DD +Y N +G+ T + E++
Sbjct: 16979 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 17013
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6217
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 152
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6218 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6265
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/127 (22%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 12 SSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKI 71
S PT + A +++++ + FL+ K + L V G+ +
Sbjct: 7365 SKPSRPTEEIQA--VDTQEAPEIFLDV-------------KLLAGLTVKAGTKIELPATV 7409
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEAT 131
G P+P++ W K D +++ + I+ + ++ I D D Y +AVN G AT
Sbjct: 7410 TGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRAT 7468
Query: 132 CTAELIV 138
E+ V
Sbjct: 7469 AVVEVNV 7475
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 103
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 27022 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27080
Query: 104 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
+LII DV D YT N G + T + + ++
Sbjct: 27081 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27118
Score = 41.2 bits (95), Expect = 3e-04
Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 18 TSPLNAEKLESEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKI 71
T + + L +D SQ +EA+ +E K V PYF+ ++D VE C+I
Sbjct: 5677 THSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEI 5736
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
D V WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5737 SK-ADAPVKWFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5784
Score = 41.2 bits (95), Expect = 3e-04
Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 16/131 (12%)
Query: 7 LSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPY--------------FSK 52
L G+K P + K+ + + LE E + K + F+K
Sbjct: 5925 LKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTK 5984
Query: 53 TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
+ D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I D
Sbjct: 5985 PLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIHDCT 6042
Query: 113 GDDDAKYTCKA 123
+D YTC A
Sbjct: 6043 PEDIKTYTCDA 6053
Score = 41.2 bits (95), Expect = 3e-04
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11210 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11268
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIV 138
D +Y N+ G T L V
Sbjct: 11269 LRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 40.8 bits (94), Expect = 5e-04
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G + + D I G P P + W K DQ + + +I D SL + D D Y
Sbjct: 16253 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYIL 16311
Query: 122 KAVNSLGEATCTAELIV 138
KA N GE + T + V
Sbjct: 16312 KAKNVAGERSVTVNVKV 16328
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 18005 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 18063
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I + DD KYT A NS G AT +IV
Sbjct: 18064 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096
Score = 39.7 bits (91), Expect = 0.001
Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 9/124 (7%)
Query: 22 NAEKLESEDVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPE 78
+ K+ + D S + +A+E+ +P F S+ + L V G++ G P P
Sbjct: 19854 SVNKVGASDPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPN 19912
Query: 79 VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
V+W K D +R + D SL I + +D KYT N L A+ T L+V
Sbjct: 19913 VLWSKPDTDLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVV 19967
Query: 139 ETME 142
+ ++
Sbjct: 19968 KVLD 19971
Score = 39.3 bits (90), Expect = 0.001
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 8071 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8130
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
D + L + D YT N LG AT + + V
Sbjct: 8131 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8171
Score = 38.9 bits (89), Expect = 0.002
Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Query: 40 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 99
A+E P ++D+ V G A+F C ++ +V W + I ES ++
Sbjct: 3481 AKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESE--RLKQS 3538
Query: 100 EDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
++GN L I +V D Y+C N GE T +A L VE E
Sbjct: 3539 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPE 3583
Score = 38.5 bits (88), Expect = 0.002
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17327 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17385
Query: 114 DDDAKYTCKAVNSLG 128
D +Y +A N G
Sbjct: 17386 IDGGQYILRASNVAG 17400
Score = 37.4 bits (85), Expect = 0.005
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 115
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8865
Query: 116 DAKYTCKAVNSLGEATCTAELIV 138
+Y A NS G A + V
Sbjct: 8866 HGRYVITATNSCGSKFAAARVEV 8888
Score = 37.0 bits (84), Expect = 0.007
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 109
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11608 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11664
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTA 134
+ D KY A NS G A +A
Sbjct: 11665 EAVRADHGKYIISAKNSSGHAQGSA 11689
Score = 37.0 bits (84), Expect = 0.007
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 39 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 92
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11882 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11941
Query: 93 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
++ D + S ++ D KY A N+ G A + V
Sbjct: 11942 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16703
Query: 117 AKYTCKAVNSLG 128
KYT NS G
Sbjct: 16704 GKYTLTLENSSG 16715
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 48 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 104
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20623
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCT 133
S++I D + Y K N++G A+ T
Sbjct: 20624 SILIKDADRLNSGCYELKLRNAMGSASAT 20652
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 33 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 89
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22326 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22384
Query: 90 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22385 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22432
Score = 35.8 bits (81), Expect = 0.015
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 129
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20991 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 21047
Score = 35.4 bits (80), Expect = 0.019
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 106
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 26069 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26126
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
I D DD Y N GEA+ A L V
Sbjct: 26127 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158
Score = 35.0 bits (79), Expect = 0.025
Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 9/129 (6%)
Query: 13 STGSPTSPLNAEKLESEDVSQAF-----LEAVAEEKP-HVKPYFSKTIRDLEVVEGSAAR 66
S+ T L +++ +D+SQ L + A+ K PYF+ + D VE
Sbjct: 5317 SSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEIT 5376
Query: 67 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 126
C++ D V WFKD + I S + I D L I D +Y C
Sbjct: 5377 LKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYVCDCGTD 5433
Query: 127 LGEATCTAE 135
+A T E
Sbjct: 5434 KTKANVTVE 5442
Score = 35.0 bits (79), Expect = 0.025
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5537 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5594
Query: 110 DVCGDDDAKYTCKA 123
+D+AKY +A
Sbjct: 5595 SAAFEDEAKYMFEA 5608
Score = 35.0 bits (79), Expect = 0.025
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 13058
Query: 117 AKYTCKAVNSLGEATCTAELIV 138
YT A NS G + T +L V
Sbjct: 13059 GDYTITAENSSGSKSATIKLKV 13080
Score = 34.7 bits (78), Expect = 0.033
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 19088 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19146
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I + +D Y NS G T +IV
Sbjct: 19147 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19179
Score = 34.3 bits (77), Expect = 0.043
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6341 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6398
Query: 114 DDDAKYTCKAVNSLGE-ATCTAELIVE 139
DD A Y N GE A LIVE
Sbjct: 6399 DDQANYNVSLTNHRGENVKSAANLIVE 6425
Score = 34.3 bits (77), Expect = 0.043
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 51 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 110
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17723 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17778
Query: 111 VCGDDDA-KYTCKAVNSLG 128
C +DA KY K NS G
Sbjct: 17779 NCDRNDAGKYILKLENSSG 17797
Score = 33.9 bits (76), Expect = 0.056
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15229
Query: 122 KAVNSLGEA 130
A N G A
Sbjct: 15230 TATNPGGFA 15238
Score = 33.9 bits (76), Expect = 0.056
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 84
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 23123 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23177
Query: 85 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 133
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 23178 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23224
Score = 33.5 bits (75), Expect = 0.073
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5271 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5328
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+V DD ++ + + E + TA+L V
Sbjct: 5329 EVTLDDISQIKAQ----VKELSSTAQLKV 5353
Score = 33.5 bits (75), Expect = 0.073
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5626 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5683
Query: 110 DVCGDDDAKYTCKAVNSLGEATCT 133
D+ DD ++ +A+ EA T
Sbjct: 5684 DLSIDDTSQIRVEAMGMSSEAKLT 5707
Score = 33.1 bits (74), Expect = 0.095
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 8/120 (6%)
Query: 21 LNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEV 79
+ A + E S AFL A++ F++ ++D+ E + A F+C+ P +V
Sbjct: 2105 VKAINIAGETSSHAFLLVQAKQLIT----FTQELQDVVAKEKDTMATFECETSE-PFVKV 2159
Query: 80 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
W+KD + E +++ D + L I + D Y+C V T TA+LIVE
Sbjct: 2160 KWYKDGMEVHEGDKYRMHSDRKVH-FLSILTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 33.1 bits (74), Expect = 0.095
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10977
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
D Y+ N G T + +++V
Sbjct: 10978 DGGIYSLTVENPAGSKTVSVKVLV 11001
Score = 32.7 bits (73), Expect = 0.12
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 114 DDDAKYTCKAVNSLGEAT 131
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 0.12
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 120
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22757 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22814
Query: 121 CKAVNSLG 128
N+ G
Sbjct: 22815 LTVKNASG 22822
Score = 32.3 bits (72), Expect = 0.16
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 55 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6254 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6309
Query: 113 GDDDAKYTCKAVNSLGEATCTAELIV 138
D Y V +G A A L V
Sbjct: 6310 LQDMGTY----VVMVGAARAAAHLTV 6331
Score = 32.3 bits (72), Expect = 0.16
Identities = 27/111 (24%), Positives = 36/111 (32%), Gaps = 30/111 (27%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQ--------------------SIRESRHF-- 94
LEV G D I G P P + W KD+ ++E F
Sbjct: 8384 LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVL 8443
Query: 95 ------QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATCTAELI 137
ID + G L + D D Y K N G +A CT ++
Sbjct: 8444 PLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8494
Score = 32.0 bits (71), Expect = 0.21
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 109
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12306 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12361
Query: 110 DVCGDDDAKYTCKAVNSLGE 129
+ DD KY+ VN GE
Sbjct: 12362 NSTRDDSGKYSLTLVNPAGE 12381
Score = 32.0 bits (71), Expect = 0.21
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468
Query: 114 DDDAKYTCKAVN 125
D +Y K N
Sbjct: 18469 TDGGQYILKLSN 18480
Score = 31.6 bits (70), Expect = 0.28
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13691 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13749
Query: 121 CKAVNSLG--EATCTAELI 137
N G E T + +++
Sbjct: 13750 ITLKNVAGTKEGTISIKVV 13768
Score = 31.2 bits (69), Expect = 0.36
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14535
Query: 115 DDAKYTCKAVNSLGE 129
D K+ N G+
Sbjct: 14536 DTGKFVMTIENPAGK 14550
Score = 31.2 bits (69), Expect = 0.36
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 120
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14832
Query: 121 CKAVNSLGE 129
A N +GE
Sbjct: 14833 LTARNIVGE 14841
Score = 31.2 bits (69), Expect = 0.36
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19491 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19549
Query: 114 DDDAKYTCKAVNSLG 128
D +Y N G
Sbjct: 19550 RDTGQYVLTLKNVAG 19564
Score = 31.2 bits (69), Expect = 0.36
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 120
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 22067 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 22122
Query: 121 CKAVNSLGEATCT 133
N+ G + T
Sbjct: 22123 LTVENNSGSKSIT 22135
Score = 31.2 bits (69), Expect = 0.36
Identities = 26/104 (25%), Positives = 36/104 (34%), Gaps = 3/104 (2%)
Query: 38 AVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
A E + K + KT+ + V G G PDP + W K I + H+
Sbjct: 24710 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24769
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Q+ + + V D Y A N G T EL V
Sbjct: 24770 QVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24813
Score = 30.8 bits (68), Expect = 0.47
Identities = 12/42 (28%), Positives = 23/42 (54%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 95
++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 30.8 bits (68), Expect = 0.47
Identities = 26/122 (21%), Positives = 54/122 (44%), Gaps = 8/122 (6%)
Query: 18 TSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 77
+S E++ + + +A + E+ P + T+ + EG I
Sbjct: 4409 SSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSE----EGDIVHLTTSITNAK-- 4462
Query: 78 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLGEATCTAEL 136
EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G+ +A+L
Sbjct: 4463 EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4521
Query: 137 IV 138
V
Sbjct: 4522 TV 4523
Score = 30.8 bits (68), Expect = 0.47
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYD 99
E P +K S ++V G + G P P++ W K++ I + + QI +
Sbjct: 9087 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 9146
Query: 100 E----DGNCSLIISDVCGDDDAKYTCKAVNSLG 128
E + L I +D YT A N LG
Sbjct: 9147 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 9179
Score = 30.8 bits (68), Expect = 0.47
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 54 IRDLEVVEGSAA-RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
+R + V+ SA R I+G P+PEV W K + + + ++ L+I +V
Sbjct: 18808 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEV---TSSFTMLVIDNVT 18864
Query: 113 GDDDAKYTCKAVNSLGEAT 131
D +Y N+ G T
Sbjct: 18865 RFDSGRYNLTLENNSGSKT 18883
Score = 30.4 bits (67), Expect = 0.62
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG------NCSLIISDVC-GD 114
GS R I+G P P+ W D ++ + + D ED N S+II C
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9579
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
KY+ A N G+ T + V
Sbjct: 9580 HTGKYSITAKNKAGQKTANCRVKV 9603
Score = 30.0 bits (66), Expect = 0.81
Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
GS + D I G P P+V +D ++ + F + + N ++ + + D +Y
Sbjct: 20186 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESVTADAGRYEI 20244
Query: 122 KAVNSLGEATCTAELIV 138
A NS G ++V
Sbjct: 20245 TAANSSGTTKAFINIVV 20261
Score = 29.6 bits (65), Expect = 1.1
Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 1/84 (1%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
+ + V G I G P P WF +RES ++ L I +
Sbjct: 23441 KTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVE-THTKVAKLTIRETTIR 23499
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
D +YT + N G + T ++I+
Sbjct: 23500 DTGEYTLELKNVTGTTSETIKVII 23523
Score = 28.1 bits (61), Expect = 3.1
Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 91
+ ++D+ V G A FDC++ Y D V W+ + + S
Sbjct: 5895 RPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPS 5933
Score = 28.1 bits (61), Expect = 3.1
Identities = 20/72 (27%), Positives = 26/72 (36%), Gaps = 1/72 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
L + G A + G P P+V WFKD+ + E I +L D
Sbjct: 10523 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK-TTPATLALEKIKAKRSDS 10581
Query: 117 AKYTCKAVNSLG 128
KY NS G
Sbjct: 10582 GKYCVVVENSTG 10593
Score = 28.1 bits (61), Expect = 3.1
Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
G + +G P P + W KD ++ES + E+ +L I + + KYT
Sbjct: 21273 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTEN-KITLSIKNAKKEHGGKYT 21330
Score = 27.7 bits (60), Expect = 4.0
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G R ++G P P++ W K + ++R+ I D + L +V D KY
Sbjct: 13403 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVNKYDAGKYIL 13461
Query: 122 KAVNSLGEATCTAELIVETME 142
NS G+ T ++V+ ++
Sbjct: 13462 TLENSCGKKEYT--IVVKVLD 13480
Score = 26.6 bits (57), Expect = 8.9
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
++RD VV G R + G P P V W +++++ + + + S++I +
Sbjct: 10224 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAI---SSSMVIKNC 10280
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIVETME 142
Y+ A N GE T +IV+ ++
Sbjct: 10281 QRSHQGVYSLLAKNEAGERKKT--IIVDVLD 10309
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 80.1 bits (196), Expect = 7e-16
Identities = 40/116 (34%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E+L ED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+K
Sbjct: 1222 EELLEEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK 1280
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
D + I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1281 DGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 75.5 bits (184), Expect = 2e-14
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E P P ++++ V+EG + +C I GYP P V W+++D I S FQI + +
Sbjct: 891 EIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QS 949
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
G L+I + +D ++TC AVN G + + L V+ EE E E
Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKE 995
Score = 73.9 bits (180), Expect = 5e-14
Identities = 38/112 (33%), Positives = 63/112 (56%), Gaps = 3/112 (2%)
Query: 27 ESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 86
E+E LE + P P+F K ++ + +G A F+ + G P P V WFK+++
Sbjct: 3682 ETESAVAKSLEKLGGPCP---PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENK 3738
Query: 87 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ S ++ I ++ +G+ + I++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3739 QLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Score = 70.1 bits (170), Expect = 7e-13
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 105
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 69.3 bits (168), Expect = 1e-12
Identities = 34/93 (36%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCS 105
KP F + + L V G RF ++ G P PE+ WF + Q I ++ ++E G
Sbjct: 3418 KPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMAL 3477
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
++I D + +Y+CKA NS GEATC A L V
Sbjct: 3478 MLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510
Score = 67.8 bits (164), Expect = 3e-12
Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 21 LNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 80
L A + S A L AE P P F + ++ + V +GS R ++ G P P V
Sbjct: 80 LKATNGSGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 81 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
+++D I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+
Sbjct: 137 FYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Query: 141 MEE 143
EE
Sbjct: 196 EEE 198
Score = 63.5 bits (153), Expect = 7e-11
Identities = 44/127 (34%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 16 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 75
SP +LE D SQ LE + KP F + +EG ARFD K+ G P
Sbjct: 1387 SPARMSPGRRLEETDESQ--LERL------YKPVFVLKPVSFKCLEGQTARFDLKVVGRP 1438
Query: 76 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 135
PE WF D Q I ++ EDG SLII D ++T A N G ++ +
Sbjct: 1439 MPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVI 1498
Query: 136 LIVETME 142
L VE +E
Sbjct: 1499 LTVEAVE 1505
Score = 63.2 bits (152), Expect = 9e-11
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 61.2 bits (147), Expect = 3e-10
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E LE S + EK P F K + + ++ G A + G P P++ WF
Sbjct: 3558 ETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFF 3617
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
+ + S ++ +D D + SLII +D+ +YTC A N G+ C+A L + + E
Sbjct: 3618 NGVLLTPSADYKFVFDGDDH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGE 3676
Query: 144 GEGEGEEE 151
G + E E
Sbjct: 3677 GHKDTETE 3684
Score = 60.8 bits (146), Expect = 4e-10
Identities = 44/143 (30%), Positives = 61/143 (42%), Gaps = 21/143 (14%)
Query: 2 AMISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVE 61
A IS +S G + + +E VS + AV EE HVK
Sbjct: 25169 ARISCGGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVK-------------- 25214
Query: 62 GSAARFDCKIEGYPDP-EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
+ CKIE Y +V W+ + + S ++I Y EDG L + D+ DD Y
Sbjct: 25215 -----YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTYR 25268
Query: 121 CKAVNSLGEATCTAELIVETMEE 143
CK VN GE + AEL V+ + E
Sbjct: 25269 CKVVNDYGEDSSYAELFVKGVRE 25291
Score = 58.9 bits (141), Expect = 2e-09
Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
D L I++ +D+ YT A N++G+ + TA L +E + E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFE 3394
Score = 58.5 bits (140), Expect = 2e-09
Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 26 LESEDV---SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWF 82
+ES DV + E A PYF ++VEG + F C++ G P P V W
Sbjct: 1011 VESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWK 1070
Query: 83 KDDQSIRESRHFQIDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
K + +++ Y+ + G C L+IS DD +YT N GE + +A L+ E
Sbjct: 1071 KSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 4e-09
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 29 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 85
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25401 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25460
Query: 86 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25461 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520
Query: 146 GEGEEEEE 153
E + +EE
Sbjct: 25521 QEFKSKEE 25528
Score = 57.4 bits (137), Expect = 5e-09
Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E+LE A ++K KP + V+EG ARF C++ GYP P+V W+
Sbjct: 1771 EELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL 1830
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
+ Q IR+S+ F++ Y DG L I D D + A N G +L ++ E+
Sbjct: 1831 NGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888
Score = 57.4 bits (137), Expect = 5e-09
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 106
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 44 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 102
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24552 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24611
Query: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
LII+ V DD Y +A N G + TA L VE
Sbjct: 24612 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24648
Score = 55.5 bits (132), Expect = 2e-08
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26820
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26821 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26856
Score = 54.3 bits (129), Expect = 4e-08
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 36 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 95
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 96 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 151
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 4e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 104
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25376
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25377 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 53.9 bits (128), Expect = 5e-08
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26469 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26528
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26529 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26578
Score = 53.5 bits (127), Expect = 7e-08
Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P + I LEV G A+F C+I+ P+ WFK + I ES I + + SL
Sbjct: 4462 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS-SLE 4520
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4521 ILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4557
Score = 53.1 bits (126), Expect = 9e-08
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24220
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24221 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24251
Score = 51.6 bits (122), Expect = 3e-07
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
+ P F V+ G + D G P P V W KD+ ++++ + E+ N
Sbjct: 15774 IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTEN-NSL 15832
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I D C +D Y K NS GEA T +IV
Sbjct: 15833 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15865
Score = 48.5 bits (114), Expect = 2e-06
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 10/105 (9%)
Query: 19 SPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 77
SP + +E V + A + +K SK I L VVE S R
Sbjct: 26325 SPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK--------- 26375
Query: 78 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCK 122
EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C+
Sbjct: 26376 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCE 26420
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 98
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.0 bits (110), Expect = 6e-06
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
E P + + + L + G + R ++G P P V WFKD I + + +I D
Sbjct: 21580 ENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DV 21638
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21639 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677
Score = 45.8 bits (107), Expect = 1e-05
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 44 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 103
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 6000 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6055
Query: 104 CSLIISDVCGDDDAKYTCK 122
L+I+ DD+A+Y+C+
Sbjct: 6056 RILVINKCLLDDEAEYSCE 6074
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 43.9 bits (102), Expect = 5e-05
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R + V EG +ARF C +G P P V W + Q + S Q+ + + IS V
Sbjct: 26196 RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK-YKSTFEISSVQAS 26254
Query: 115 DDAKYTCKAVNSLGEATCTAELIVE 139
D+ Y+ NS G+ L ++
Sbjct: 26255 DEGNYSVVVENSEGKQEAEFTLTIQ 26279
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 49 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 108
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 109 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 152
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 9e-05
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 109
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9754 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9812
Query: 110 DVCGDDDAKYTCKAVNSLGEAT 131
D YT AVN+LG A+
Sbjct: 9813 QSRRSDTGLYTITAVNNLGTAS 9834
Score = 43.1 bits (100), Expect = 9e-05
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12516 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12575
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12576 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616
Score = 42.7 bits (99), Expect = 1e-04
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 50 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 103
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4745 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4802
Query: 104 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
+I DV D +YTC E T TA+L+VE +
Sbjct: 4803 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838
Score = 42.4 bits (98), Expect = 2e-04
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16857 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16911
Query: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 137
+L I + DD +Y N +G+ T + E++
Sbjct: 16912 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16946
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6150
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 152
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6151 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6198
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/127 (22%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 12 SSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKI 71
S PT + A +++++ + FL+ K + L V G+ +
Sbjct: 7298 SKPSRPTEEIQA--VDTQEAPEIFLDV-------------KLLAGLTVKAGTKIELPATV 7342
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEAT 131
G P+P++ W K D +++ + I+ + ++ I D D Y +AVN G AT
Sbjct: 7343 TGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRAT 7401
Query: 132 CTAELIV 138
E+ V
Sbjct: 7402 AVVEVNV 7408
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 103
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 26955 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27013
Query: 104 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
+LII DV D YT N G + T + + ++
Sbjct: 27014 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27051
Score = 41.2 bits (95), Expect = 3e-04
Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 18 TSPLNAEKLESEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKI 71
T + + L +D SQ +EA+ +E K V PYF+ ++D VE C+I
Sbjct: 5610 THSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEI 5669
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
D V WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5670 SK-ADAPVKWFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5717
Score = 41.2 bits (95), Expect = 3e-04
Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 16/131 (12%)
Query: 7 LSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPY--------------FSK 52
L G+K P + K+ + + LE E + K + F+K
Sbjct: 5858 LKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTK 5917
Query: 53 TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
+ D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I D
Sbjct: 5918 PLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIHDCT 5975
Query: 113 GDDDAKYTCKA 123
+D YTC A
Sbjct: 5976 PEDIKTYTCDA 5986
Score = 41.2 bits (95), Expect = 3e-04
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11143 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11201
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIV 138
D +Y N+ G T L V
Sbjct: 11202 LRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 40.8 bits (94), Expect = 5e-04
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G + + D I G P P + W K DQ + + +I D SL + D D Y
Sbjct: 16186 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYIL 16244
Query: 122 KAVNSLGEATCTAELIV 138
KA N GE + T + V
Sbjct: 16245 KAKNVAGERSVTVNVKV 16261
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 17938 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17996
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I + DD KYT A NS G AT +IV
Sbjct: 17997 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029
Score = 39.7 bits (91), Expect = 0.001
Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 9/124 (7%)
Query: 22 NAEKLESEDVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPE 78
+ K+ + D S + +A+E+ +P F S+ + L V G++ G P P
Sbjct: 19787 SVNKVGASDPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPN 19845
Query: 79 VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
V+W K D +R + D SL I + +D KYT N L A+ T L+V
Sbjct: 19846 VLWSKPDTDLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVV 19900
Query: 139 ETME 142
+ ++
Sbjct: 19901 KVLD 19904
Score = 39.3 bits (90), Expect = 0.001
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 8004 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8063
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
D + L + D YT N LG AT + + V
Sbjct: 8064 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8104
Score = 38.5 bits (88), Expect = 0.002
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17260 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17318
Query: 114 DDDAKYTCKAVNSLG 128
D +Y +A N G
Sbjct: 17319 IDGGQYILRASNVAG 17333
Score = 37.4 bits (85), Expect = 0.005
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 115
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8798
Query: 116 DAKYTCKAVNSLGEATCTAELIV 138
+Y A NS G A + V
Sbjct: 8799 HGRYVITATNSCGSKFAAARVEV 8821
Score = 37.0 bits (84), Expect = 0.007
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 109
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11541 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11597
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTA 134
+ D KY A NS G A +A
Sbjct: 11598 EAVRADHGKYIISAKNSSGHAQGSA 11622
Score = 37.0 bits (84), Expect = 0.007
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 39 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 92
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11815 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11874
Query: 93 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
++ D + S ++ D KY A N+ G A + V
Sbjct: 11875 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16636
Query: 117 AKYTCKAVNSLG 128
KYT NS G
Sbjct: 16637 GKYTLTLENSSG 16648
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 48 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 104
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20556
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCT 133
S++I D + Y K N++G A+ T
Sbjct: 20557 SILIKDADRLNSGCYELKLRNAMGSASAT 20585
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 33 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 89
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22259 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22317
Query: 90 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22318 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22365
Score = 35.8 bits (81), Expect = 0.015
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 129
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20924 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20980
Score = 35.4 bits (80), Expect = 0.019
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 106
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 26002 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26059
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
I D DD Y N GEA+ A L V
Sbjct: 26060 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091
Score = 35.0 bits (79), Expect = 0.025
Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 9/129 (6%)
Query: 13 STGSPTSPLNAEKLESEDVSQAF-----LEAVAEEKP-HVKPYFSKTIRDLEVVEGSAAR 66
S+ T L +++ +D+SQ L + A+ K PYF+ + D VE
Sbjct: 5250 SSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEIT 5309
Query: 67 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 126
C++ D V WFKD + I S + I D L I D +Y C
Sbjct: 5310 LKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYVCDCGTD 5366
Query: 127 LGEATCTAE 135
+A T E
Sbjct: 5367 KTKANVTVE 5375
Score = 35.0 bits (79), Expect = 0.025
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5470 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5527
Query: 110 DVCGDDDAKYTCKA 123
+D+AKY +A
Sbjct: 5528 SAAFEDEAKYMFEA 5541
Score = 35.0 bits (79), Expect = 0.025
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12991
Query: 117 AKYTCKAVNSLGEATCTAELIV 138
YT A NS G + T +L V
Sbjct: 12992 GDYTITAENSSGSKSATIKLKV 13013
Score = 34.7 bits (78), Expect = 0.033
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 19021 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19079
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I + +D Y NS G T +IV
Sbjct: 19080 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19112
Score = 34.3 bits (77), Expect = 0.043
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6274 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6331
Query: 114 DDDAKYTCKAVNSLGE-ATCTAELIVE 139
DD A Y N GE A LIVE
Sbjct: 6332 DDQANYNVSLTNHRGENVKSAANLIVE 6358
Score = 34.3 bits (77), Expect = 0.043
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 51 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 110
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17656 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17711
Query: 111 VCGDDDA-KYTCKAVNSLG 128
C +DA KY K NS G
Sbjct: 17712 NCDRNDAGKYILKLENSSG 17730
Score = 33.9 bits (76), Expect = 0.056
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15162
Query: 122 KAVNSLGEA 130
A N G A
Sbjct: 15163 TATNPGGFA 15171
Score = 33.9 bits (76), Expect = 0.056
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 84
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 23056 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23110
Query: 85 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 133
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 23111 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23157
Score = 33.5 bits (75), Expect = 0.073
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5204 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5261
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+V DD ++ + + E + TA+L V
Sbjct: 5262 EVTLDDISQIKAQ----VKELSSTAQLKV 5286
Score = 33.5 bits (75), Expect = 0.073
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5559 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5616
Query: 110 DVCGDDDAKYTCKAVNSLGEATCT 133
D+ DD ++ +A+ EA T
Sbjct: 5617 DLSIDDTSQIRVEAMGMSSEAKLT 5640
Score = 33.1 bits (74), Expect = 0.095
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 8/120 (6%)
Query: 21 LNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEV 79
+ A + E S AFL A++ F++ ++D+ E + A F+C+ P +V
Sbjct: 2105 VKAINIAGETSSHAFLLVQAKQLIT----FTQELQDVVAKEKDTMATFECETSE-PFVKV 2159
Query: 80 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
W+KD + E +++ D + L I + D Y+C V T TA+LIVE
Sbjct: 2160 KWYKDGMEVHEGDKYRMHSDRKVH-FLSILTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 33.1 bits (74), Expect = 0.095
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10910
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
D Y+ N G T + +++V
Sbjct: 10911 DGGIYSLTVENPAGSKTVSVKVLV 10934
Score = 32.7 bits (73), Expect = 0.12
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 114 DDDAKYTCKAVNSLGEAT 131
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 0.12
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 120
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22690 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22747
Query: 121 CKAVNSLG 128
N+ G
Sbjct: 22748 LTVKNASG 22755
Score = 32.3 bits (72), Expect = 0.16
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 55 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6187 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6242
Query: 113 GDDDAKYTCKAVNSLGEATCTAELIV 138
D Y V +G A A L V
Sbjct: 6243 LQDMGTY----VVMVGAARAAAHLTV 6264
Score = 32.3 bits (72), Expect = 0.16
Identities = 27/111 (24%), Positives = 36/111 (32%), Gaps = 30/111 (27%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQ--------------------SIRESRHF-- 94
LEV G D I G P P + W KD+ ++E F
Sbjct: 8317 LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVL 8376
Query: 95 ------QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATCTAELI 137
ID + G L + D D Y K N G +A CT ++
Sbjct: 8377 PLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8427
Score = 32.0 bits (71), Expect = 0.21
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 109
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12239 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12294
Query: 110 DVCGDDDAKYTCKAVNSLGE 129
+ DD KY+ VN GE
Sbjct: 12295 NSTRDDSGKYSLTLVNPAGE 12314
Score = 32.0 bits (71), Expect = 0.21
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401
Query: 114 DDDAKYTCKAVN 125
D +Y K N
Sbjct: 18402 TDGGQYILKLSN 18413
Score = 31.6 bits (70), Expect = 0.28
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13624 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13682
Query: 121 CKAVNSLG--EATCTAELI 137
N G E T + +++
Sbjct: 13683 ITLKNVAGTKEGTISIKVV 13701
Score = 31.2 bits (69), Expect = 0.36
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14468
Query: 115 DDAKYTCKAVNSLGE 129
D K+ N G+
Sbjct: 14469 DTGKFVMTIENPAGK 14483
Score = 31.2 bits (69), Expect = 0.36
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 120
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14765
Query: 121 CKAVNSLGE 129
A N +GE
Sbjct: 14766 LTARNIVGE 14774
Score = 31.2 bits (69), Expect = 0.36
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19424 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19482
Query: 114 DDDAKYTCKAVNSLG 128
D +Y N G
Sbjct: 19483 RDTGQYVLTLKNVAG 19497
Score = 31.2 bits (69), Expect = 0.36
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 120
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 22000 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 22055
Query: 121 CKAVNSLGEATCT 133
N+ G + T
Sbjct: 22056 LTVENNSGSKSIT 22068
Score = 31.2 bits (69), Expect = 0.36
Identities = 26/104 (25%), Positives = 36/104 (34%), Gaps = 3/104 (2%)
Query: 38 AVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
A E + K + KT+ + V G G PDP + W K I + H+
Sbjct: 24643 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24702
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Q+ + + V D Y A N G T EL V
Sbjct: 24703 QVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24746
Score = 30.8 bits (68), Expect = 0.47
Identities = 12/42 (28%), Positives = 23/42 (54%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 95
++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 30.8 bits (68), Expect = 0.47
Identities = 26/122 (21%), Positives = 54/122 (44%), Gaps = 8/122 (6%)
Query: 18 TSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 77
+S E++ + + +A + E+ P + T+ + EG I
Sbjct: 4342 SSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSE----EGDIVHLTTSITNAK-- 4395
Query: 78 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLGEATCTAEL 136
EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G+ +A+L
Sbjct: 4396 EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4454
Query: 137 IV 138
V
Sbjct: 4455 TV 4456
Score = 30.8 bits (68), Expect = 0.47
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYD 99
E P +K S ++V G + G P P++ W K++ I + + QI +
Sbjct: 9020 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 9079
Query: 100 E----DGNCSLIISDVCGDDDAKYTCKAVNSLG 128
E + L I +D YT A N LG
Sbjct: 9080 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 9112
Score = 30.8 bits (68), Expect = 0.47
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 54 IRDLEVVEGSAA-RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
+R + V+ SA R I+G P+PEV W K + + + ++ L+I +V
Sbjct: 18741 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEV---TSSFTMLVIDNVT 18797
Query: 113 GDDDAKYTCKAVNSLGEAT 131
D +Y N+ G T
Sbjct: 18798 RFDSGRYNLTLENNSGSKT 18816
Score = 30.4 bits (67), Expect = 0.62
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG------NCSLIISDVC-GD 114
GS R I+G P P+ W D ++ + + D ED N S+II C
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9512
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
KY+ A N G+ T + V
Sbjct: 9513 HTGKYSITAKNKAGQKTANCRVKV 9536
Score = 30.0 bits (66), Expect = 0.81
Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
GS + D I G P P+V +D ++ + F + + N ++ + + D +Y
Sbjct: 20119 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESVTADAGRYEI 20177
Query: 122 KAVNSLGEATCTAELIV 138
A NS G ++V
Sbjct: 20178 TAANSSGTTKAFINIVV 20194
Score = 29.6 bits (65), Expect = 1.1
Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 1/84 (1%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
+ + V G I G P P WF +RES ++ L I +
Sbjct: 23374 KTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVE-THTKVAKLTIRETTIR 23432
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
D +YT + N G + T ++I+
Sbjct: 23433 DTGEYTLELKNVTGTTSETIKVII 23456
Score = 28.1 bits (61), Expect = 3.1
Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 91
+ ++D+ V G A FDC++ Y D V W+ + + S
Sbjct: 5828 RPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPS 5866
Score = 28.1 bits (61), Expect = 3.1
Identities = 20/72 (27%), Positives = 26/72 (36%), Gaps = 1/72 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
L + G A + G P P+V WFKD+ + E I +L D
Sbjct: 10456 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK-TTPATLALEKIKAKRSDS 10514
Query: 117 AKYTCKAVNSLG 128
KY NS G
Sbjct: 10515 GKYCVVVENSTG 10526
Score = 28.1 bits (61), Expect = 3.1
Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
G + +G P P + W KD ++ES + E+ +L I + + KYT
Sbjct: 21206 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTEN-KITLSIKNAKKEHGGKYT 21263
Score = 27.7 bits (60), Expect = 4.0
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G R ++G P P++ W K + ++R+ I D + L +V D KY
Sbjct: 13336 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVNKYDAGKYIL 13394
Query: 122 KAVNSLGEATCTAELIVETME 142
NS G+ T ++V+ ++
Sbjct: 13395 TLENSCGKKEYT--IVVKVLD 13413
Score = 26.6 bits (57), Expect = 8.9
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
++RD VV G R + G P P V W +++++ + + + S++I +
Sbjct: 10157 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAI---SSSMVIKNC 10213
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIVETME 142
Y+ A N GE T +IV+ ++
Sbjct: 10214 QRSHQGVYSLLAKNEAGERKKT--IIVDVLD 10242
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 80.1 bits (196), Expect = 7e-16
Identities = 40/116 (34%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E+L ED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+K
Sbjct: 1222 EELLEEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK 1280
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
D + I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1281 DGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 75.5 bits (184), Expect = 2e-14
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E P P ++++ V+EG + +C I GYP P V W+++D I S FQI + +
Sbjct: 891 EIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QS 949
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
G L+I + +D ++TC AVN G + + L V+ EE E E
Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKE 995
Score = 73.9 bits (180), Expect = 5e-14
Identities = 38/112 (33%), Positives = 63/112 (56%), Gaps = 3/112 (2%)
Query: 27 ESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 86
E+E LE + P P+F K ++ + +G A F+ + G P P V WFK+++
Sbjct: 3557 ETESAVAKSLEKLGGPCP---PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENK 3613
Query: 87 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ S ++ I ++ +G+ + I++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3614 QLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 70.1 bits (170), Expect = 7e-13
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 105
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 67.8 bits (164), Expect = 3e-12
Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 21 LNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 80
L A + S A L AE P P F + ++ + V +GS R ++ G P P V
Sbjct: 80 LKATNGSGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVK 136
Query: 81 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
+++D I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+
Sbjct: 137 FYRDGAEIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Query: 141 MEE 143
EE
Sbjct: 196 EEE 198
Score = 63.5 bits (153), Expect = 7e-11
Identities = 44/127 (34%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 16 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 75
SP +LE D SQ LE + KP F + +EG ARFD K+ G P
Sbjct: 1387 SPARMSPGRRLEETDESQ--LERL------YKPVFVLKPVSFKCLEGQTARFDLKVVGRP 1438
Query: 76 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 135
PE WF D Q I ++ EDG SLII D ++T A N G ++ +
Sbjct: 1439 MPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVI 1498
Query: 136 LIVETME 142
L VE +E
Sbjct: 1499 LTVEAVE 1505
Score = 63.2 bits (152), Expect = 9e-11
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 61.2 bits (147), Expect = 3e-10
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E LE S + EK P F K + + ++ G A + G P P++ WF
Sbjct: 3433 ETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFF 3492
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
+ + S ++ +D D + SLII +D+ +YTC A N G+ C+A L + + E
Sbjct: 3493 NGVLLTPSADYKFVFDGDDH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGE 3551
Query: 144 GEGEGEEE 151
G + E E
Sbjct: 3552 GHKDTETE 3559
Score = 60.8 bits (146), Expect = 4e-10
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 152
D L I++ +D+ YT A N++G+ + TA L +E E E E+E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3401
Score = 60.8 bits (146), Expect = 4e-10
Identities = 44/143 (30%), Positives = 61/143 (42%), Gaps = 21/143 (14%)
Query: 2 AMISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVE 61
A IS +S G + + +E VS + AV EE HVK
Sbjct: 25044 ARISCGGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVK-------------- 25089
Query: 62 GSAARFDCKIEGYPDP-EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
+ CKIE Y +V W+ + + S ++I Y EDG L + D+ DD Y
Sbjct: 25090 -----YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDITKLDDGTYR 25143
Query: 121 CKAVNSLGEATCTAELIVETMEE 143
CK VN GE + AEL V+ + E
Sbjct: 25144 CKVVNDYGEDSSYAELFVKGVRE 25166
Score = 58.5 bits (140), Expect = 2e-09
Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 26 LESEDV---SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWF 82
+ES DV + E A PYF ++VEG + F C++ G P P V W
Sbjct: 1011 VESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWK 1070
Query: 83 KDDQSIRESRHFQIDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
K + +++ Y+ + G C L+IS DD +YT N GE + +A L+ E
Sbjct: 1071 KSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 4e-09
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 29 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 85
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25276 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25335
Query: 86 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25336 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395
Query: 146 GEGEEEEE 153
E + +EE
Sbjct: 25396 QEFKSKEE 25403
Score = 57.4 bits (137), Expect = 5e-09
Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 24 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E+LE A ++K KP + V+EG ARF C++ GYP P+V W+
Sbjct: 1771 EELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL 1830
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
+ Q IR+S+ F++ Y DG L I D D + A N G +L ++ E+
Sbjct: 1831 NGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888
Score = 57.4 bits (137), Expect = 5e-09
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 106
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 44 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 102
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24427 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24486
Query: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
LII+ V DD Y +A N G + TA L VE
Sbjct: 24487 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523
Score = 55.5 bits (132), Expect = 2e-08
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26695
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26696 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26731
Score = 54.3 bits (129), Expect = 4e-08
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 36 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 95
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 96 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 151
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 4e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 104
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25251
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 53.9 bits (128), Expect = 5e-08
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26344 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26403
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 147
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26404 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26453
Score = 53.5 bits (127), Expect = 7e-08
Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P + I LEV G A+F C+I+ P+ WFK + I ES I + + SL
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS-SLE 4395
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4396 ILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4432
Score = 53.1 bits (126), Expect = 9e-08
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24096 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24126
Score = 51.6 bits (122), Expect = 3e-07
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
+ P F V+ G + D G P P V W KD+ ++++ + E+ N
Sbjct: 15649 IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTEN-NSL 15707
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I D C +D Y K NS GEA T +IV
Sbjct: 15708 LTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15740
Score = 48.5 bits (114), Expect = 2e-06
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 10/105 (9%)
Query: 19 SPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVEGSAARFDCKIEGYPDP 77
SP + +E V + A + +K SK I L VVE S R
Sbjct: 26200 SPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAK--------- 26250
Query: 78 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCK 122
EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C+
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCE 26295
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 98
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.0 bits (110), Expect = 6e-06
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
E P + + + L + G + R ++G P P V WFKD I + + +I D
Sbjct: 21455 ENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DV 21513
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21514 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552
Score = 45.8 bits (107), Expect = 1e-05
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 44 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 103
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 5875 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 5930
Query: 104 CSLIISDVCGDDDAKYTCK 122
L+I+ DD+A+Y+C+
Sbjct: 5931 RILVINKCLLDDEAEYSCE 5949
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 43.9 bits (102), Expect = 5e-05
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R + V EG +ARF C +G P P V W + Q + S Q+ + + IS V
Sbjct: 26071 RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK-YKSTFEISSVQAS 26129
Query: 115 DDAKYTCKAVNSLGEATCTAELIVE 139
D+ Y+ NS G+ L ++
Sbjct: 26130 DEGNYSVVVENSEGKQEAEFTLTIQ 26154
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 49 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 108
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 109 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 152
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 9e-05
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 109
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9629 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9687
Query: 110 DVCGDDDAKYTCKAVNSLGEAT 131
D YT AVN+LG A+
Sbjct: 9688 QSRRSDTGLYTITAVNNLGTAS 9709
Score = 43.1 bits (100), Expect = 9e-05
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12391 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12450
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12451 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491
Score = 42.7 bits (99), Expect = 1e-04
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 50 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 103
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4620 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4677
Query: 104 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
+I DV D +YTC E T TA+L+VE +
Sbjct: 4678 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713
Score = 42.4 bits (98), Expect = 2e-04
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16732 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16786
Query: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 137
+L I + DD +Y N +G+ T + E++
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16821
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6025
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 152
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6026 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6073
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/127 (22%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 12 SSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKI 71
S PT + A +++++ + FL+ K + L V G+ +
Sbjct: 7173 SKPSRPTEEIQA--VDTQEAPEIFLDV-------------KLLAGLTVKAGTKIELPATV 7217
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEAT 131
G P+P++ W K D +++ + I+ + ++ I D D Y +AVN G AT
Sbjct: 7218 TGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRAT 7276
Query: 132 CTAELIV 138
E+ V
Sbjct: 7277 AVVEVNV 7283
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 103
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 26888
Query: 104 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
+LII DV D YT N G + T + + ++
Sbjct: 26889 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 26926
Score = 41.2 bits (95), Expect = 3e-04
Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 18 TSPLNAEKLESEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKI 71
T + + L +D SQ +EA+ +E K V PYF+ ++D VE C+I
Sbjct: 5485 THSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEI 5544
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
D V WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5545 SK-ADAPVKWFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5592
Score = 41.2 bits (95), Expect = 3e-04
Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 16/131 (12%)
Query: 7 LSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPY--------------FSK 52
L G+K P + K+ + + LE E + K + F+K
Sbjct: 5733 LKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTK 5792
Query: 53 TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
+ D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I D
Sbjct: 5793 PLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIHDCT 5850
Query: 113 GDDDAKYTCKA 123
+D YTC A
Sbjct: 5851 PEDIKTYTCDA 5861
Score = 41.2 bits (95), Expect = 3e-04
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11018 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11076
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIV 138
D +Y N+ G T L V
Sbjct: 11077 LRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 40.8 bits (94), Expect = 5e-04
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G + + D I G P P + W K DQ + + +I D SL + D D Y
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYIL 16119
Query: 122 KAVNSLGEATCTAELIV 138
KA N GE + T + V
Sbjct: 16120 KAKNVAGERSVTVNVKV 16136
Score = 40.8 bits (94), Expect = 5e-04
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17871
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I + DD KYT A NS G AT +IV
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 39.7 bits (91), Expect = 0.001
Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 9/124 (7%)
Query: 22 NAEKLESEDVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPE 78
+ K+ + D S + +A+E+ +P F S+ + L V G++ G P P
Sbjct: 19662 SVNKVGASDPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPN 19720
Query: 79 VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
V+W K D +R + D SL I + +D KYT N L A+ T L+V
Sbjct: 19721 VLWSKPDTDLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVV 19775
Query: 139 ETME 142
+ ++
Sbjct: 19776 KVLD 19779
Score = 39.3 bits (90), Expect = 0.001
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 37 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 7879 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 7938
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
D + L + D YT N LG AT + + V
Sbjct: 7939 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 38.5 bits (88), Expect = 0.002
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17135 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17193
Query: 114 DDDAKYTCKAVNSLG 128
D +Y +A N G
Sbjct: 17194 IDGGQYILRASNVAG 17208
Score = 37.4 bits (85), Expect = 0.005
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 115
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8673
Query: 116 DAKYTCKAVNSLGEATCTAELIV 138
+Y A NS G A + V
Sbjct: 8674 HGRYVITATNSCGSKFAAARVEV 8696
Score = 37.0 bits (84), Expect = 0.007
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 109
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11416 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11472
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTA 134
+ D KY A NS G A +A
Sbjct: 11473 EAVRADHGKYIISAKNSSGHAQGSA 11497
Score = 37.0 bits (84), Expect = 0.007
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 39 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 92
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11690 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11749
Query: 93 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
++ D + S ++ D KY A N+ G A + V
Sbjct: 11750 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16511
Query: 117 AKYTCKAVNSLG 128
KYT NS G
Sbjct: 16512 GKYTLTLENSSG 16523
Score = 37.0 bits (84), Expect = 0.007
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 48 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 104
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20431
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCT 133
S++I D + Y K N++G A+ T
Sbjct: 20432 SILIKDADRLNSGCYELKLRNAMGSASAT 20460
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 33 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 89
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22134 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22192
Query: 90 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22193 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22240
Score = 35.8 bits (81), Expect = 0.015
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 72 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 129
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20855
Score = 35.4 bits (80), Expect = 0.019
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 106
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 25934
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
I D DD Y N GEA+ A L V
Sbjct: 25935 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 35.0 bits (79), Expect = 0.025
Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 9/129 (6%)
Query: 13 STGSPTSPLNAEKLESEDVSQAF-----LEAVAEEKP-HVKPYFSKTIRDLEVVEGSAAR 66
S+ T L +++ +D+SQ L + A+ K PYF+ + D VE
Sbjct: 5125 SSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEIT 5184
Query: 67 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 126
C++ D V WFKD + I S + I D L I D +Y C
Sbjct: 5185 LKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYVCDCGTD 5241
Query: 127 LGEATCTAE 135
+A T E
Sbjct: 5242 KTKANVTVE 5250
Score = 35.0 bits (79), Expect = 0.025
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5345 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5402
Query: 110 DVCGDDDAKYTCKA 123
+D+AKY +A
Sbjct: 5403 SAAFEDEAKYMFEA 5416
Score = 35.0 bits (79), Expect = 0.025
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12866
Query: 117 AKYTCKAVNSLGEATCTAELIV 138
YT A NS G + T +L V
Sbjct: 12867 GDYTITAENSSGSKSATIKLKV 12888
Score = 34.7 bits (78), Expect = 0.033
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 18896 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 18954
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
L I + +D Y NS G T +IV
Sbjct: 18955 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 18987
Score = 34.3 bits (77), Expect = 0.043
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6149 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6206
Query: 114 DDDAKYTCKAVNSLGE-ATCTAELIVE 139
DD A Y N GE A LIVE
Sbjct: 6207 DDQANYNVSLTNHRGENVKSAANLIVE 6233
Score = 34.3 bits (77), Expect = 0.043
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 51 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 110
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17531 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17586
Query: 111 VCGDDDA-KYTCKAVNSLG 128
C +DA KY K NS G
Sbjct: 17587 NCDRNDAGKYILKLENSSG 17605
Score = 33.9 bits (76), Expect = 0.056
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15037
Query: 122 KAVNSLGEA 130
A N G A
Sbjct: 15038 TATNPGGFA 15046
Score = 33.9 bits (76), Expect = 0.056
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 84
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 22931 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 22985
Query: 85 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 133
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 22986 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23032
Score = 33.5 bits (75), Expect = 0.073
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5079 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5136
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+V DD ++ + + E + TA+L V
Sbjct: 5137 EVTLDDISQIKAQ----VKELSSTAQLKV 5161
Score = 33.5 bits (75), Expect = 0.073
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5434 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5491
Query: 110 DVCGDDDAKYTCKAVNSLGEATCT 133
D+ DD ++ +A+ EA T
Sbjct: 5492 DLSIDDTSQIRVEAMGMSSEAKLT 5515
Score = 33.1 bits (74), Expect = 0.095
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 8/120 (6%)
Query: 21 LNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEV 79
+ A + E S AFL A++ F++ ++D+ E + A F+C+ P +V
Sbjct: 2105 VKAINIAGETSSHAFLLVQAKQLIT----FTQELQDVVAKEKDTMATFECETSE-PFVKV 2159
Query: 80 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
W+KD + E +++ D + L I + D Y+C V T TA+LIVE
Sbjct: 2160 KWYKDGMEVHEGDKYRMHSDRKVH-FLSILTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 33.1 bits (74), Expect = 0.095
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10785
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
D Y+ N G T + +++V
Sbjct: 10786 DGGIYSLTVENPAGSKTVSVKVLV 10809
Score = 32.7 bits (73), Expect = 0.12
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 114 DDDAKYTCKAVNSLGEAT 131
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 0.12
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 120
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22622
Query: 121 CKAVNSLG 128
N+ G
Sbjct: 22623 LTVKNASG 22630
Score = 32.3 bits (72), Expect = 0.16
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 55 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6062 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6117
Query: 113 GDDDAKYTCKAVNSLGEATCTAELIV 138
D Y V +G A A L V
Sbjct: 6118 LQDMGTY----VVMVGAARAAAHLTV 6139
Score = 32.3 bits (72), Expect = 0.16
Identities = 27/111 (24%), Positives = 36/111 (32%), Gaps = 30/111 (27%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQ--------------------SIRESRHF-- 94
LEV G D I G P P + W KD+ ++E F
Sbjct: 8192 LEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVL 8251
Query: 95 ------QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG--EATCTAELI 137
ID + G L + D D Y K N G +A CT ++
Sbjct: 8252 PLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8302
Score = 32.0 bits (71), Expect = 0.21
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 109
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12114 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12169
Query: 110 DVCGDDDAKYTCKAVNSLGE 129
+ DD KY+ VN GE
Sbjct: 12170 NSTRDDSGKYSLTLVNPAGE 12189
Score = 32.0 bits (71), Expect = 0.21
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276
Query: 114 DDDAKYTCKAVN 125
D +Y K N
Sbjct: 18277 TDGGQYILKLSN 18288
Score = 31.6 bits (70), Expect = 0.28
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13557
Query: 121 CKAVNSLG--EATCTAELI 137
N G E T + +++
Sbjct: 13558 ITLKNVAGTKEGTISIKVV 13576
Score = 31.2 bits (69), Expect = 0.36
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14343
Query: 115 DDAKYTCKAVNSLGE 129
D K+ N G+
Sbjct: 14344 DTGKFVMTIENPAGK 14358
Score = 31.2 bits (69), Expect = 0.36
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 120
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14640
Query: 121 CKAVNSLGE 129
A N +GE
Sbjct: 14641 LTARNIVGE 14649
Score = 31.2 bits (69), Expect = 0.36
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 55 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19299 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19357
Query: 114 DDDAKYTCKAVNSLG 128
D +Y N G
Sbjct: 19358 RDTGQYVLTLKNVAG 19372
Score = 31.2 bits (69), Expect = 0.36
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 120
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 21875 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 21930
Query: 121 CKAVNSLGEATCT 133
N+ G + T
Sbjct: 21931 LTVENNSGSKSIT 21943
Score = 31.2 bits (69), Expect = 0.36
Identities = 26/104 (25%), Positives = 36/104 (34%), Gaps = 3/104 (2%)
Query: 38 AVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
A E + K + KT+ + V G G PDP + W K I + H+
Sbjct: 24518 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24577
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Q+ + + V D Y A N G T EL V
Sbjct: 24578 QVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24621
Score = 30.8 bits (68), Expect = 0.47
Identities = 12/42 (28%), Positives = 23/42 (54%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 95
++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 30.8 bits (68), Expect = 0.47
Identities = 26/122 (21%), Positives = 54/122 (44%), Gaps = 8/122 (6%)
Query: 18 TSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 77
+S E++ + + +A + E+ P + T+ + EG I
Sbjct: 4217 SSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSE----EGDIVHLTTSITNAK-- 4270
Query: 78 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLGEATCTAEL 136
EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G+ +A+L
Sbjct: 4271 EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4329
Query: 137 IV 138
V
Sbjct: 4330 TV 4331
Score = 30.8 bits (68), Expect = 0.47
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYD 99
E P +K S ++V G + G P P++ W K++ I + + QI +
Sbjct: 8895 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 8954
Query: 100 E----DGNCSLIISDVCGDDDAKYTCKAVNSLG 128
E + L I +D YT A N LG
Sbjct: 8955 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 8987
Score = 30.8 bits (68), Expect = 0.47
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 54 IRDLEVVEGSAA-RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 112
+R + V+ SA R I+G P+PEV W K + + + ++ L+I +V
Sbjct: 18616 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEV---TSSFTMLVIDNVT 18672
Query: 113 GDDDAKYTCKAVNSLGEAT 131
D +Y N+ G T
Sbjct: 18673 RFDSGRYNLTLENNSGSKT 18691
Score = 30.4 bits (67), Expect = 0.62
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 7/84 (8%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG------NCSLIISDVC-GD 114
GS R I+G P P+ W D ++ + + D ED N S+II C
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9387
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
KY+ A N G+ T + V
Sbjct: 9388 HTGKYSITAKNKAGQKTANCRVKV 9411
Score = 30.0 bits (66), Expect = 0.81
Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
GS + D I G P P+V +D ++ + F + + N ++ + + D +Y
Sbjct: 19994 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESVTADAGRYEI 20052
Query: 122 KAVNSLGEATCTAELIV 138
A NS G ++V
Sbjct: 20053 TAANSSGTTKAFINIVV 20069
Score = 29.6 bits (65), Expect = 1.1
Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 1/84 (1%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 114
+ + V G I G P P WF +RES ++ L I +
Sbjct: 23249 KTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVE-THTKVAKLTIRETTIR 23307
Query: 115 DDAKYTCKAVNSLGEATCTAELIV 138
D +YT + N G + T ++I+
Sbjct: 23308 DTGEYTLELKNVTGTTSETIKVII 23331
Score = 28.1 bits (61), Expect = 3.1
Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 91
+ ++D+ V G A FDC++ Y D V W+ + + S
Sbjct: 5703 RPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPS 5741
Score = 28.1 bits (61), Expect = 3.1
Identities = 20/72 (27%), Positives = 26/72 (36%), Gaps = 1/72 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
L + G A + G P P+V WFKD+ + E I +L D
Sbjct: 10331 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK-TTPATLALEKIKAKRSDS 10389
Query: 117 AKYTCKAVNSLG 128
KY NS G
Sbjct: 10390 GKYCVVVENSTG 10401
Score = 28.1 bits (61), Expect = 3.1
Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
G + +G P P + W KD ++ES + E+ +L I + + KYT
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTEN-KITLSIKNAKKEHGGKYT 21138
Score = 27.7 bits (60), Expect = 4.0
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 121
G R ++G P P++ W K + ++R+ I D + L +V D KY
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVNKYDAGKYIL 13269
Query: 122 KAVNSLGEATCTAELIVETME 142
NS G+ T ++V+ ++
Sbjct: 13270 TLENSCGKKEYT--IVVKVLD 13288
Score = 26.6 bits (57), Expect = 8.9
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 53 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
++RD VV G R + G P P V W +++++ + + + S++I +
Sbjct: 10032 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAI---SSSMVIKNC 10088
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIVETME 142
Y+ A N GE T +IV+ ++
Sbjct: 10089 QRSHQGVYSLLAKNEAGERKKT--IIVDVLD 10117
>gi|93102361 palladin [Homo sapiens]
Length = 1106
Score = 77.0 bits (188), Expect = 6e-15
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHFQIDYDEDGNCSL 106
P+F ++ ++ EG F C++ G P P++ WFKD + I +S H+ I D DG CSL
Sbjct: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
+ DDD YT A N G +CT L+V+ + +
Sbjct: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQ 873
Score = 68.2 bits (165), Expect = 3e-12
Identities = 42/140 (30%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 3 MISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEG 62
M+ ++ R S SP+ + + S +E+ +P+F + DL V EG
Sbjct: 867 MVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER-FFRPHFLQAPGDLTVQEG 925
Query: 63 SAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCK 122
R DCK+ G P P++ W D + +R ++ E+G SLII V D YTC
Sbjct: 926 KLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCI 985
Query: 123 AVNSLGEATCTAELIVETME 142
A N G+ + + EL+V E
Sbjct: 986 ATNRAGQNSFSLELVVAAKE 1005
Score = 67.8 bits (164), Expect = 3e-12
Identities = 33/102 (32%), Positives = 52/102 (50%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F + +R EV EGS +C++ G P P V WF + + + + QI + +LI
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 149
I++ DD +YTC A N G T +AE+ +E + + E
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372
Score = 63.9 bits (154), Expect = 5e-11
Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 7/98 (7%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-------DYDE 100
P F+K +++ V EG +C++ G P +V WF+ I++S F+I +
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ C+L+I++ +D +TC A N G AT TA+L+V
Sbjct: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Score = 60.8 bits (146), Expect = 4e-10
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 39 VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR-HFQID 97
VA ++ H P F + +++ V +G R +C++ G P P++ W K+++S+ S +
Sbjct: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
Query: 98 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
D G L+I +D YT A N G +CTA L V
Sbjct: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 71.2 bits (173), Expect = 3e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F +++ EV +G FDC + G P P V WFKD + + E H+ I+ D+ G LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I+ V D Y C A NS+G ++ AEL V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217
Score = 68.6 bits (166), Expect = 2e-12
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
E K P FS T D E G A R +C + D W KD + + RH ID
Sbjct: 4891 EMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG 4950
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 152
DG CSL+I+ + D YTC+ N G+ T +A ++V E+ E GE ++
Sbjct: 4951 DGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDD 5005
Score = 63.5 bits (153), Expect = 7e-11
Identities = 25/92 (27%), Positives = 49/92 (53%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F + + D G + C++ G P P + W+KD ++++ H + D DG+C+LI
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ + G D +Y C A ++ G + +++V+
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ 6105
Score = 62.0 bits (149), Expect = 2e-10
Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ-IDYDEDGNC 104
V P F +R VEG A+F C IEG P P++ W+KD + FQ + G
Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
L+I +D Y C+ VN LG A +AEL +++
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 59.7 bits (143), Expect = 9e-10
Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Query: 48 PYFSKTIRDLEVVEGSA-ARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
P + +RDL+V G+ A+F K++GYP P + WFKD Q + S H ++ D+ +L
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTL 5318
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
I V +D +Y N++G A +A L+V +E E
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE 5357
Score = 53.9 bits (128), Expect = 5e-08
Identities = 35/99 (35%), Positives = 43/99 (43%), Gaps = 2/99 (2%)
Query: 40 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 99
AE P P S R V EG AR C + G P PE VW KD Q + E R + D
Sbjct: 232 AEGAPASPP--STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYED 289
Query: 100 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
N L I D YTC A N +G+ + ++V
Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 52.4 bits (124), Expect = 2e-07
Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
Query: 38 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 97
A AE+ PH F + V EGS A F C++ G P P V W KD + + E ++
Sbjct: 104 ACAEQAPH----FLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVR 159
Query: 98 YDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
+E G S L I D Y +A N LG A+ A L+V++
Sbjct: 160 VEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203
Score = 52.0 bits (123), Expect = 2e-07
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F + V G A C+I G P P+V W KD Q + F++ D D L
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLT 68
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I D+ D +Y C+A N++GEA L V+
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100
Score = 48.1 bits (113), Expect = 3e-06
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F K ++DLEV E +A F C++ P E WFK++ + S + I+ +E L +
Sbjct: 335 FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIE-EEGTERRLTVR 392
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+V DDDA Y C+ + AEL V+
Sbjct: 393 NVSADDDAVYICETPEG---SRTVAELAVQ 419
Score = 47.8 bits (112), Expect = 4e-06
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 41 EEKPH-------VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH 93
EEKP V P + +V +GS+ F K+EG P P V W +++ E
Sbjct: 5357 EEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---ERGV 5413
Query: 94 FQIDYDEDGNC--------SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
I D G SL++ DV YTC A N+ G+A C+A L V + + E
Sbjct: 5414 LWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473
Query: 146 GEGEEEE 152
+ + +E
Sbjct: 5474 EQEKVKE 5480
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 45 HVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 103
H +P F + ++DLEV+EG AA C + P V W + +R + + E
Sbjct: 3181 HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSL-RQEGAM 3238
Query: 104 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
L++ ++ D +Y+C S G+ T +A L V +
Sbjct: 3239 LELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTAL 3272
Score = 37.0 bits (84), Expect = 0.007
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
+P F + ++ L+ EGS A C++ P VVW K ++ + + + L
Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRL-QGCTAEL 3946
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCT 133
++ D+ +D +YTC + AT T
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLT 3973
Score = 36.6 bits (83), Expect = 0.009
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
+ +RD +E +C++ +V WFK Q ++ +++ D LIISDV
Sbjct: 2294 RPLRDKIAMEKHRGVLECQVSR-ASAQVRWFKGSQELQPGPKYELVSDGLYR-KLIISDV 2351
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIVE 139
+D+ YTC A G+ +A+ VE
Sbjct: 2352 HAEDEDTYTCDA----GDVKTSAQFFVE 2375
Score = 34.7 bits (78), Expect = 0.033
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
EG A F C + D VVWF+D ++ S F I + SL ISD+ +D + T
Sbjct: 1912 EGGEATFQCVVSP-SDVAVVWFRDGALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQIT 1969
Query: 121 CKAVNSLGEA 130
+A + A
Sbjct: 1970 VEAEGASSSA 1979
Score = 34.3 bits (77), Expect = 0.043
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 7/105 (6%)
Query: 49 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 108
+F +R E +EG+ A C++ E W K +S+R+ + D C L I
Sbjct: 3363 HFIGRLRHQESIEGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQD-GAVCELQI 3419
Query: 109 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
+ D +Y+C GE +A L V+ + EG EE
Sbjct: 3420 CGLAVADAGEYSCVC----GEERTSATLTVKALPAKFTEGLRNEE 3460
Score = 34.3 bits (77), Expect = 0.043
Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 40 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV---VWFKDDQSIRESRHFQI 96
A+ K K + + ++E +EG A F+C++ PEV W DD+ + S + ++
Sbjct: 4332 AQLKVTAKNTVVRGLENVEALEGGEALFECQLS---QPEVAAHTWLLDDEPVHTSENAEV 4388
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ E+G L++ D +C+ G+ +A L V
Sbjct: 4389 VFFENGLRHLLLLKNLRPQD---SCRVTFLAGDMVTSAFLTV 4427
Score = 32.7 bits (73), Expect = 0.12
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 56 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCG 113
+++ G+ A C++ P EV W+KD + + S ++ E C+ L++ V
Sbjct: 1175 EVQAEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRM---EVKGCTRRLVVQQVGK 1230
Query: 114 DDDAKYTCKA 123
D +Y+C+A
Sbjct: 1231 ADAGEYSCEA 1240
Score = 32.3 bits (72), Expect = 0.16
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
K + D V G C++ P V W KD ++IR+S+ + + E L+I
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDV-VCEGTMAMLVIRGA 2888
Query: 112 CGDDDAKYTCKAVNSLGEATCTAE 135
D +YTC+ S A+ E
Sbjct: 2889 SLKDAGEYTCEVEASKSTASLHVE 2912
Score = 32.3 bits (72), Expect = 0.16
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F++ +R+ E VEG+ A C++ E W K +++R+ + I E C L I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCELQIC 3508
Query: 110 DVCGDDDAKYTCKAVNSLGEATCT 133
+ D +Y C AT T
Sbjct: 3509 GLAMADAGEYLCVCGQERTSATLT 3532
Score = 32.0 bits (71), Expect = 0.21
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+ D++V EGS+A F C+I V WF D + + +ID G L + +
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070
Query: 114 DDDAKYTCKAVNSLGEATC---------TAELIVETMEEGE 145
D +A + A + EL T+ EGE
Sbjct: 3071 KDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE 3111
Score = 31.2 bits (69), Expect = 0.36
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC--SLIISDVCGDDDAKY 119
G++A C++ EV W+KD + + S +I E C L++ D +Y
Sbjct: 1273 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRI---EAAGCMRQLVVQQAGQADAGEY 1328
Query: 120 TCKA 123
TC+A
Sbjct: 1329 TCEA 1332
Score = 31.2 bits (69), Expect = 0.36
Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVC 112
R+++ G++A C++ EV W+KD + + S ++ E C+ L++
Sbjct: 1634 REVQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRV---EAVGCTRRLVVQQAG 1689
Query: 113 GDDDAKYTCKA 123
D +Y+C+A
Sbjct: 1690 QADAGEYSCEA 1700
Score = 30.0 bits (66), Expect = 0.81
Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
++ V G A+F+C+ V W+KD + S + D L+ + V D+
Sbjct: 807 VDAVAGGPAQFECETSE-AHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDE 865
Query: 117 AKYTCK 122
Y+C+
Sbjct: 866 GTYSCR 871
Score = 29.3 bits (64), Expect = 1.4
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 13/97 (13%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV-WFKDDQSIRESRHFQIDYDEDGNCS 105
+P KT R+L+ V S + P P+ V W+KDD + S F++ E
Sbjct: 2473 RPLEPKTGRELQSVVLSC-------DFRPAPKAVQWYKDDTPLSPSEKFKMSL-EGQMAE 2524
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
L I + D Y C+A G A + E+ VE E
Sbjct: 2525 LRILRLMPADAGVYRCQA----GSAHSSTEVTVEARE 2557
Score = 28.9 bits (63), Expect = 1.8
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 8/90 (8%)
Query: 51 SKTIRDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 108
+K ++ +EV+EG + F+C + E DP +W +++ S FQ G +++
Sbjct: 2739 TKRLKTMEVLEGESCSFECVLSHESASDP-AMWTVGGKTVGSSSRFQA--TRQGRKYILV 2795
Query: 109 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
DA +V L T A LIV
Sbjct: 2796 VREAAPSDAGEVVFSVRGL---TSKASLIV 2822
Score = 27.7 bits (60), Expect = 4.0
Identities = 17/76 (22%), Positives = 31/76 (40%), Gaps = 2/76 (2%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV-WFKDDQSIRESRHFQIDYDEDGNCS 105
+P F ++ LE G AR C++ VV W K+ + +++ +
Sbjct: 4067 RPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEM-RSQGATRE 4125
Query: 106 LIISDVCGDDDAKYTC 121
L+I + D +Y C
Sbjct: 4126 LLIHQLEAKDTGEYAC 4141
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 71.2 bits (173), Expect = 3e-13
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F +++ EV +G FDC + G P P V WFKD + + E H+ I+ D+ G LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I+ V D Y C A NS+G ++ AEL V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217
Score = 68.6 bits (166), Expect = 2e-12
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 41 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 100
E K P FS T D E G A R +C + D W KD + + RH ID
Sbjct: 4891 EMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG 4950
Query: 101 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 152
DG CSL+I+ + D YTC+ N G+ T +A ++V E+ E GE ++
Sbjct: 4951 DGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDD 5005
Score = 63.9 bits (154), Expect = 5e-11
Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P TI D++ G A+F+ IEG P P V W+KD + +S E SL+
Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLS-QQQEGTTYSLV 6415
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
+ V D YTC A N+ G+ C AEL+V G+ E + E++
Sbjct: 6416 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV---LGGDNEPDSEKQ 6458
Score = 63.5 bits (153), Expect = 7e-11
Identities = 25/92 (27%), Positives = 49/92 (53%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F + + D G + C++ G P P + W+KD ++++ H + D DG+C+LI
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ + G D +Y C A ++ G + +++V+
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ 6105
Score = 62.0 bits (149), Expect = 2e-10
Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ-IDYDEDGNC 104
V P F +R VEG A+F C IEG P P++ W+KD + FQ + G
Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165
Query: 105 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
L+I +D Y C+ VN LG A +AEL +++
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 59.7 bits (143), Expect = 9e-10
Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Query: 48 PYFSKTIRDLEVVEGSA-ARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
P + +RDL+V G+ A+F K++GYP P + WFKD Q + S H ++ D+ +L
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTL 5318
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
I V +D +Y N++G A +A L+V +E E
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE 5357
Score = 53.9 bits (128), Expect = 5e-08
Identities = 35/99 (35%), Positives = 43/99 (43%), Gaps = 2/99 (2%)
Query: 40 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 99
AE P P S R V EG AR C + G P PE VW KD Q + E R + D
Sbjct: 232 AEGAPASPP--STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYED 289
Query: 100 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
N L I D YTC A N +G+ + ++V
Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 52.4 bits (124), Expect = 2e-07
Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
Query: 38 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 97
A AE+ PH F + V EGS A F C++ G P P V W KD + + E ++
Sbjct: 104 ACAEQAPH----FLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVR 159
Query: 98 YDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
+E G S L I D Y +A N LG A+ A L+V++
Sbjct: 160 VEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203
Score = 52.0 bits (123), Expect = 2e-07
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F + V G A C+I G P P+V W KD Q + F++ D D L
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLT 68
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I D+ D +Y C+A N++GEA L V+
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100
Score = 48.1 bits (113), Expect = 3e-06
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F K ++DLEV E +A F C++ P E WFK++ + S + I+ +E L +
Sbjct: 335 FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIE-EEGTERRLTVR 392
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+V DDDA Y C+ + AEL V+
Sbjct: 393 NVSADDDAVYICETPEG---SRTVAELAVQ 419
Score = 47.8 bits (112), Expect = 4e-06
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 41 EEKPH-------VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH 93
EEKP V P + +V +GS+ F K+EG P P V W +++ E
Sbjct: 5357 EEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---ERGV 5413
Query: 94 FQIDYDEDGNC--------SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
I D G SL++ DV YTC A N+ G+A C+A L V + + E
Sbjct: 5414 LWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473
Query: 146 GEGEEEE 152
+ + +E
Sbjct: 5474 EQEKVKE 5480
Score = 43.5 bits (101), Expect = 7e-05
Identities = 26/89 (29%), Positives = 35/89 (39%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F + + D VV G + C++ P + W KD + S I L
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 136
I V +D YTC N+LG T T L
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 45 HVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 103
H +P F + ++DLEV+EG AA C + P V W + +R + + E
Sbjct: 3181 HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSL-RQEGAM 3238
Query: 104 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
L++ ++ D +Y+C S G+ T +A L V +
Sbjct: 3239 LELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTAL 3272
Score = 37.0 bits (84), Expect = 0.007
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
+P F + ++ L+ EGS A C++ P VVW K ++ + + + L
Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRL-QGCTAEL 3946
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCT 133
++ D+ +D +YTC + AT T
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLT 3973
Score = 36.6 bits (83), Expect = 0.009
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
+ +RD +E +C++ +V WFK Q ++ +++ D LIISDV
Sbjct: 2294 RPLRDKIAMEKHRGVLECQVSR-ASAQVRWFKGSQELQPGPKYELVSDGLYR-KLIISDV 2351
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIVE 139
+D+ YTC A G+ +A+ VE
Sbjct: 2352 HAEDEDTYTCDA----GDVKTSAQFFVE 2375
Score = 34.7 bits (78), Expect = 0.033
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
EG A F C + D VVWF+D ++ S F I + SL ISD+ +D + T
Sbjct: 1912 EGGEATFQCVVSP-SDVAVVWFRDGALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQIT 1969
Query: 121 CKAVNSLGEA 130
+A + A
Sbjct: 1970 VEAEGASSSA 1979
Score = 34.3 bits (77), Expect = 0.043
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 7/105 (6%)
Query: 49 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 108
+F +R E +EG+ A C++ E W K +S+R+ + D C L I
Sbjct: 3363 HFIGRLRHQESIEGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQD-GAVCELQI 3419
Query: 109 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
+ D +Y+C GE +A L V+ + EG EE
Sbjct: 3420 CGLAVADAGEYSCVC----GEERTSATLTVKALPAKFTEGLRNEE 3460
Score = 34.3 bits (77), Expect = 0.043
Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 40 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV---VWFKDDQSIRESRHFQI 96
A+ K K + + ++E +EG A F+C++ PEV W DD+ + S + ++
Sbjct: 4332 AQLKVTAKNTVVRGLENVEALEGGEALFECQLS---QPEVAAHTWLLDDEPVHTSENAEV 4388
Query: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ E+G L++ D +C+ G+ +A L V
Sbjct: 4389 VFFENGLRHLLLLKNLRPQD---SCRVTFLAGDMVTSAFLTV 4427
Score = 32.7 bits (73), Expect = 0.12
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 56 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCG 113
+++ G+ A C++ P EV W+KD + + S ++ E C+ L++ V
Sbjct: 1175 EVQAEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRM---EVKGCTRRLVVQQVGK 1230
Query: 114 DDDAKYTCKA 123
D +Y+C+A
Sbjct: 1231 ADAGEYSCEA 1240
Score = 32.3 bits (72), Expect = 0.16
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 52 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 111
K + D V G C++ P V W KD ++IR+S+ + + E L+I
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDV-VCEGTMAMLVIRGA 2888
Query: 112 CGDDDAKYTCKAVNSLGEATCTAE 135
D +YTC+ S A+ E
Sbjct: 2889 SLKDAGEYTCEVEASKSTASLHVE 2912
Score = 32.3 bits (72), Expect = 0.16
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 50 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 109
F++ +R+ E VEG+ A C++ E W K +++R+ + I E C L I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCELQIC 3508
Query: 110 DVCGDDDAKYTCKAVNSLGEATCT 133
+ D +Y C AT T
Sbjct: 3509 GLAMADAGEYLCVCGQERTSATLT 3532
Score = 32.0 bits (71), Expect = 0.21
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 113
+ D++V EGS+A F C+I V WF D + + +ID G L + +
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070
Query: 114 DDDAKYTCKAVNSLGEATC---------TAELIVETMEEGE 145
D +A + A + EL T+ EGE
Sbjct: 3071 KDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE 3111
Score = 31.2 bits (69), Expect = 0.36
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
Query: 62 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC--SLIISDVCGDDDAKY 119
G++A C++ EV W+KD + + S +I E C L++ D +Y
Sbjct: 1273 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRI---EAAGCMRQLVVQQAGQADAGEY 1328
Query: 120 TCKA 123
TC+A
Sbjct: 1329 TCEA 1332
Score = 31.2 bits (69), Expect = 0.36
Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 55 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVC 112
R+++ G++A C++ EV W+KD + + S ++ E C+ L++
Sbjct: 1634 REVQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRV---EAVGCTRRLVVQQAG 1689
Query: 113 GDDDAKYTCKA 123
D +Y+C+A
Sbjct: 1690 QADAGEYSCEA 1700
Score = 30.0 bits (66), Expect = 0.81
Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
++ V G A+F+C+ V W+KD + S + D L+ + V D+
Sbjct: 807 VDAVAGGPAQFECETSE-AHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDE 865
Query: 117 AKYTCK 122
Y+C+
Sbjct: 866 GTYSCR 871
Score = 29.3 bits (64), Expect = 1.4
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 13/97 (13%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV-WFKDDQSIRESRHFQIDYDEDGNCS 105
+P KT R+L+ V S + P P+ V W+KDD + S F++ E
Sbjct: 2473 RPLEPKTGRELQSVVLSC-------DFRPAPKAVQWYKDDTPLSPSEKFKMSL-EGQMAE 2524
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
L I + D Y C+A G A + E+ VE E
Sbjct: 2525 LRILRLMPADAGVYRCQA----GSAHSSTEVTVEARE 2557
Score = 28.9 bits (63), Expect = 1.8
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 8/90 (8%)
Query: 51 SKTIRDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 108
+K ++ +EV+EG + F+C + E DP +W +++ S FQ G +++
Sbjct: 2739 TKRLKTMEVLEGESCSFECVLSHESASDP-AMWTVGGKTVGSSSRFQA--TRQGRKYILV 2795
Query: 109 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
DA +V L T A LIV
Sbjct: 2796 VREAAPSDAGEVVFSVRGL---TSKASLIV 2822
Score = 27.7 bits (60), Expect = 4.0
Identities = 17/76 (22%), Positives = 31/76 (40%), Gaps = 2/76 (2%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV-WFKDDQSIRESRHFQIDYDEDGNCS 105
+P F ++ LE G AR C++ VV W K+ + +++ +
Sbjct: 4067 RPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEM-RSQGATRE 4125
Query: 106 LIISDVCGDDDAKYTC 121
L+I + D +Y C
Sbjct: 4126 LLIHQLEAKDTGEYAC 4141
>gi|115511036 alpha-kinase 3 [Homo sapiens]
Length = 1907
Score = 65.9 bits (159), Expect = 1e-11
Identities = 41/130 (31%), Positives = 63/130 (48%), Gaps = 3/130 (2%)
Query: 17 PTSPLNAEKLESEDVSQA-FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 75
P + L++ +L ++ F +A+ +P F T++ V E S RF C + GYP
Sbjct: 247 PETSLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRSVSEDSDVRFTCIVTGYP 306
Query: 76 DPEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAK-YTCKAVNSLGEATCT 133
+PEV W+KDD + R + + GN + C ++DA Y A NS G +C+
Sbjct: 307 EPEVTWYKDDTELDRYCGLPKYEITHQGNRHTLQLYRCREEDAAIYQASAQNSKGIVSCS 366
Query: 134 AELIVETMEE 143
L V TM E
Sbjct: 367 GVLEVGTMTE 376
>gi|156104903 myomesin 2 [Homo sapiens]
Length = 1465
Score = 63.9 bits (154), Expect = 5e-11
Identities = 35/105 (33%), Positives = 51/105 (48%), Gaps = 9/105 (8%)
Query: 33 QAFLEAVAEEKPHVKPYFSKTIRD---------LEVVEGSAARFDCKIEGYPDPEVVWFK 83
QAF EA AE + F++ R + ++EG C + G PDPEV+WFK
Sbjct: 1321 QAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFK 1380
Query: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 128
+DQ I+ S HF + ++ S+ I V +D KY+ N G
Sbjct: 1381 NDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425
Score = 39.3 bits (90), Expect = 0.001
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 10/131 (7%)
Query: 24 EKLESEDVSQAFLEAVA------EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 77
+KL+ + Q + +A EE+ P +R V E + + ++G+P P
Sbjct: 124 DKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTP 183
Query: 78 EVVWFKDDQSI---RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 134
V W+KD I E ++I+ G +L I+ DD A Y+ A N+ G+ + A
Sbjct: 184 VVQWYKDGSLICQAAEPGKYRIE-SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNA 242
Query: 135 ELIVETMEEGE 145
++V E
Sbjct: 243 AVVVRRFRGDE 253
Score = 38.1 bits (87), Expect = 0.003
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 61 EGSAARFDCKIEGYPD-----PEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 115
EG C + PD P W++DD ++ES+ ++ + E G SL S + DD
Sbjct: 291 EGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGE-GQASLSFSHLHKDD 349
Query: 116 DAKYTCKAVNSLGEATCTAELIV 138
+ YT + V+ G + +A L V
Sbjct: 350 EGLYTLRIVSRGGVSDHSAFLFV 372
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 62.8 bits (151), Expect = 1e-10
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 6/118 (5%)
Query: 27 ESEDVSQAFLEAVAEEKPHVK---PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
E E+ + AE++ + P+F K +++ VV+ RF K+ G P PE+ W+
Sbjct: 558 EEEEEGSIMNGSTAEDEEQTRSGAPWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWWF 617
Query: 84 DDQSIRESRHFQIDYDEDGNC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 140
+ + +++ +Q Y E G L + + +D +Y CKAVN+ G A T L +E+
Sbjct: 618 EGEILQDGEDYQ--YIERGETYCLYLPETFPEDGGEYMCKAVNNKGSAASTCILTIES 673
>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
Length = 1141
Score = 61.2 bits (147), Expect = 3e-10
Identities = 39/101 (38%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 41 EEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 97
E K H + P F + D VV G +A +C + G+P P+VVW K+ IRE F I
Sbjct: 1038 EYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLIT 1097
Query: 98 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ G +L I D YTC+AVN LGEA +L V
Sbjct: 1098 -NYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
Score = 40.0 bits (92), Expect = 8e-04
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 9/103 (8%)
Query: 35 FLEAVAEEKPHVKP------YFSKTIRD-LEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 87
FLE E P +P KT + + VV G+ R D I G P P W K D+
Sbjct: 525 FLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDE- 583
Query: 88 IRESRHFQIDYDEDGNC-SLIISDVCGDDDAKYTCKAVNSLGE 129
+ + + ++ +C S +I +D+ +YT K N +GE
Sbjct: 584 VFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGE 626
>gi|209693444 myotilin isoform b [Homo sapiens]
Length = 314
Score = 59.3 bits (142), Expect = 1e-09
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 4/126 (3%)
Query: 17 PTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD 76
PTS + + DV+ +A+ E+ P F + ++ + EG R D K+ G P
Sbjct: 39 PTSQVRSRSTSRGDVNDQ--DAIQEK--FYPPRFIQVPENMSIDEGRFCRMDFKVSGLPA 94
Query: 77 PEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 136
P+V W+ + ++++ ++ E G SLI V D Y C A N GEAT T +L
Sbjct: 95 PDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL 154
Query: 137 IVETME 142
V E
Sbjct: 155 DVLAKE 160
Score = 54.7 bits (130), Expect = 3e-08
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 36 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHF 94
L+ +A+E P F + +V+EG + + +C+I P P++ W ++++ ++ +
Sbjct: 154 LDVLAKEHKRA-PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ D G +L+I DV D YT AVN G TC L V
Sbjct: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
>gi|5803106 myotilin isoform a [Homo sapiens]
Length = 498
Score = 59.3 bits (142), Expect = 1e-09
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 4/126 (3%)
Query: 17 PTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD 76
PTS + + DV+ +A+ E+ P F + ++ + EG R D K+ G P
Sbjct: 223 PTSQVRSRSTSRGDVNDQ--DAIQEK--FYPPRFIQVPENMSIDEGRFCRMDFKVSGLPA 278
Query: 77 PEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 136
P+V W+ + ++++ ++ E G SLI V D Y C A N GEAT T +L
Sbjct: 279 PDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL 338
Query: 137 IVETME 142
V E
Sbjct: 339 DVLAKE 344
Score = 54.7 bits (130), Expect = 3e-08
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 36 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHF 94
L+ +A+E P F + +V+EG + + +C+I P P++ W ++++ ++ +
Sbjct: 338 LDVLAKEHKRA-PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 396
Query: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
+ D G +L+I DV D YT AVN G TC L V
Sbjct: 397 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 440
>gi|148839296 immunoglobulin-like and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 868
Score = 59.3 bits (142), Expect = 1e-09
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
KP F +R + +G C ++G P P V WFK+D+S+ E D G CSL
Sbjct: 773 KPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSL-EGNPAVYSTDLLGVCSL 831
Query: 107 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
I V D +Y A N+LG+A TA LIV
Sbjct: 832 TIPSVSPKDSGEYKAVAENTLGQAVSTATLIV 863
Score = 40.0 bits (92), Expect = 8e-04
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 49 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC-SLI 107
+FS+ + D+EV G AA C + P WFKD ++ + + + +DG SL
Sbjct: 74 HFSQGLADMEVQPGEAATLSCTLTSDLGPG-TWFKD--GVKLTTQDGVIFKQDGLVHSLF 130
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAE 135
I+ V G +YT A + EAT T +
Sbjct: 131 ITHVQGTQAGRYTFVAGDQQSEATLTVQ 158
Score = 28.9 bits (63), Expect = 1.8
Identities = 19/64 (29%), Positives = 24/64 (37%), Gaps = 3/64 (4%)
Query: 57 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 116
L V G R E P PEV W KD + + + +DG L+I D
Sbjct: 575 LTVKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKR---SVTVTKDGLTQLLIPVAGLSDS 631
Query: 117 AKYT 120
YT
Sbjct: 632 GLYT 635
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform
1 precursor [Homo sapiens]
Length = 1907
Score = 57.8 bits (138), Expect = 4e-09
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
KP F K D + G A F C+ G P P + W K + + R I++D+ L
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 107 IISDV-CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
I + D+A Y C A NSLGE +A+L V E+
Sbjct: 92 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQ 129
Score = 40.4 bits (93), Expect = 6e-04
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 7/96 (7%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P FS EV+ G + C G P P V W + + + + G
Sbjct: 230 VAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPV-----GRNV 284
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
L +S+V A YTC A++SLG TA++ V+ +
Sbjct: 285 LELSNVVRS--ANYTCVAISSLGMIEATAQVTVKAL 318
Score = 36.6 bits (83), Expect = 0.009
Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 10/77 (12%)
Query: 57 LEVVEGS-AARFDCKIEGYPDPEVVWFKD----DQSIRESRHFQIDYDEDGNCSLIISDV 111
L+VVE + A C G PDPE+ WFKD D + R Q+ + +L I
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-----RSGALQIESS 197
Query: 112 CGDDDAKYTCKAVNSLG 128
D KY C A NS G
Sbjct: 198 EESDQGKYECVATNSAG 214
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform
2 precursor [Homo sapiens]
Length = 1898
Score = 57.8 bits (138), Expect = 4e-09
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 47 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 106
KP F K D + G A F C+ G P P + W K + + R I++D+ L
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 107 IISDV-CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
I + D+A Y C A NSLGE +A+L V E+
Sbjct: 92 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQ 129
Score = 40.4 bits (93), Expect = 6e-04
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 7/96 (7%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P FS EV+ G + C G P P V W + + + + G
Sbjct: 230 VAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPV-----GRNV 284
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
L +S+V A YTC A++SLG TA++ V+ +
Sbjct: 285 LELSNVVRS--ANYTCVAISSLGMIEATAQVTVKAL 318
Score = 36.6 bits (83), Expect = 0.009
Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 10/77 (12%)
Query: 57 LEVVEGS-AARFDCKIEGYPDPEVVWFKD----DQSIRESRHFQIDYDEDGNCSLIISDV 111
L+VVE + A C G PDPE+ WFKD D + R Q+ + +L I
Sbjct: 143 LKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQL-----RSGALQIESS 197
Query: 112 CGDDDAKYTCKAVNSLG 128
D KY C A NS G
Sbjct: 198 EESDQGKYECVATNSAG 214
>gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor
[Homo sapiens]
Length = 1338
Score = 57.0 bits (136), Expect = 6e-09
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
PY + + D V S+ DC G P+P++ WFK++ I++ + G+ +L
Sbjct: 661 PYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILG---PGSSTLF 717
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
I V +D+ Y CKA N G +A L V+
Sbjct: 718 IERVTEEDEGVYHCKATNQKGSVESSAYLTVQ 749
Score = 39.7 bits (91), Expect = 0.001
Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 9/67 (13%)
Query: 57 LEVVEGSAA-RFDCKIEGYPDPEVVWFKDDQSIRE--SRHFQIDYDEDGNCSLIISDVCG 113
LE V G + R K++ +P PEVVW KD E +R+ Y SLII DV
Sbjct: 344 LETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGY------SLIIKDVTE 397
Query: 114 DDDAKYT 120
+D YT
Sbjct: 398 EDAGNYT 404
>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
Length = 1274
Score = 56.6 bits (135), Expect = 8e-09
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
P F++ + + V+ G A C + G P P++ WFK+ + E F++ + + G +L
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLE 1239
Query: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
I C D Y C+A N GEA C L V
Sbjct: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 32.0 bits (71), Expect = 0.21
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 58 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 117
+V +G R ++ + D EV W K+ Q I+ S I +L IS DDA
Sbjct: 374 QVSKGHKIRLTVELADH-DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDA 432
Query: 118 KYTCKAVNSLGEATCTAELIVE 139
Y C +G C+ EL V+
Sbjct: 433 AYQC----VVGGEKCSTELFVK 450
Score = 31.6 bits (70), Expect = 0.28
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
Query: 51 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSLIIS 109
++ + D V+ G F+C++ +V W KD + F+ + +DG LII+
Sbjct: 457 TRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIIN 515
Query: 110 DVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
+ +D Y S G+A AELIV+
Sbjct: 516 EAMLEDAGHYA--LCTSGGQA--LAELIVQ 541
Score = 27.3 bits (59), Expect = 5.2
Identities = 12/25 (48%), Positives = 14/25 (56%)
Query: 59 VVEGSAARFDCKIEGYPDPEVVWFK 83
VV G+ R D I G P P V+W K
Sbjct: 661 VVAGNKLRLDVPISGDPAPTVIWQK 685
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 56.6 bits (135), Expect = 8e-09
Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 45 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD---DQSIRESRHFQIDYDED 101
+V P F+KT D+ + + AR +C G+P+P++ W KD D R + D+D
Sbjct: 596 NVLPSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDD 655
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
I+DV DD Y+C A NS G + A L V
Sbjct: 656 ---VFFITDVKIDDAGVYSCTAQNSAGSISANATLTV 689
Score = 51.6 bits (122), Expect = 3e-07
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 54 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ--SIRESRHFQIDYDEDGNCSLIISDV 111
+ D V G CK G P P + WFK D+ S+ E H D N L++ +V
Sbjct: 699 LEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD-----NQLLVVQNV 753
Query: 112 CGDDDAKYTCKAVNSLGEATCTAELIV 138
+D +YTC+ N+LG ++L V
Sbjct: 754 VAEDAGRYTCEMSNTLGTERAHSQLSV 780
>gi|11321597 kinase insert domain receptor precursor [Homo sapiens]
Length = 1356
Score = 55.5 bits (132), Expect = 2e-08
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 3/98 (3%)
Query: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
V P + + + G + C G P P+++WFKD++++ E + +DGN +
Sbjct: 665 VAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVL---KDGNRN 721
Query: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 143
L I V +D+ YTC+A + LG A A I+E +E
Sbjct: 722 LTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQE 759
Score = 33.5 bits (75), Expect = 0.073
Identities = 23/88 (26%), Positives = 35/88 (39%), Gaps = 9/88 (10%)
Query: 45 HVKPY--FSKTIRDL-EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
H KP+ F + L E G R K GYP PE+ W+K+ + + + +
Sbjct: 325 HEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPLESNHTIKAGH--- 381
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGE 129
L I +V D YT N + +
Sbjct: 382 ---VLTIMEVSERDTGNYTVILTNPISK 406
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 55.1 bits (131), Expect = 2e-08
Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 4/100 (4%)
Query: 40 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 99
A E+P P F K +D V G A F C+ G P P V W K + + R I++D
Sbjct: 28 AAEEP---PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFD 84
Query: 100 EDGNCSLIISDV-CGDDDAKYTCKAVNSLGEATCTAELIV 138
E L I + D+ Y C A NS+GE T A+L V
Sbjct: 85 ESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTV 124
Score = 42.4 bits (98), Expect = 2e-04
Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 7/105 (6%)
Query: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
E V P FS E++ G C G P P V W + + + +
Sbjct: 230 EVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV----- 284
Query: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 146
G L ++DV D A YTC A++SLG A++ V+++ + G
Sbjct: 285 GRNVLELTDV--KDSANYTCVAMSSLGVIEAVAQITVKSLPKAPG 327
Score = 39.7 bits (91), Expect = 0.001
Identities = 33/93 (35%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
Query: 57 LEVVEGS-AARFDCKIEGYPDPEVVWFKD----DQSIRESRHFQIDYDEDGNCSLIISDV 111
L+VVE + A C G PDPE+ WFKD D S R Q+ + +L I
Sbjct: 143 LKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQL-----RSGALQIESS 197
Query: 112 CGDDDAKYTCKAVNSLG-EATCTAELIVETMEE 143
D KY C A NS G + A L V + E
Sbjct: 198 EETDQGKYECVATNSAGVRYSSPANLYVRELRE 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,404,235
Number of Sequences: 37866
Number of extensions: 271619
Number of successful extensions: 2924
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 217
Number of HSP's successfully gapped in prelim test: 101
Number of HSP's that attempted gapping in prelim test: 1050
Number of HSP's gapped (non-prelim): 1482
length of query: 153
length of database: 18,247,518
effective HSP length: 93
effective length of query: 60
effective length of database: 14,725,980
effective search space: 883558800
effective search space used: 883558800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.