Guide to the Human Genome
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Search of human proteins with 169234719

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169234719 lin-54 homolog isoform a [Homo sapiens]
         (749 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169234719 lin-54 homolog isoform a [Homo sapiens]                 1479   0.0  
gi|169234723 lin-54 homolog isoform b [Homo sapiens]                 1047   0.0  
gi|169234721 lin-54 homolog isoform b [Homo sapiens]                 1047   0.0  
gi|40806200 metallothionein-like 5, testis-specific isoform a [H...   249   5e-66
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              67   6e-11
gi|91982772 mucin 17 [Homo sapiens]                                    67   6e-11
gi|19923559 EMSY protein [Homo sapiens]                                67   8e-11
gi|116284392 mucin 2 precursor [Homo sapiens]                          66   1e-10
gi|167736355 mucin 4 isoform a [Homo sapiens]                          63   9e-10
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       62   1e-09
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      56   1e-07
gi|98986457 host cell factor 1 [Homo sapiens]                          56   1e-07
gi|161019170 mucin 5AC [Homo sapiens]                                  54   4e-07
gi|151301154 mucin 6, gastric [Homo sapiens]                           53   9e-07
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         53   9e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    53   9e-07
gi|224458301 family with sequence similarity 186, member A [Homo...    53   1e-06
gi|83367077 mucin 16 [Homo sapiens]                                    53   1e-06
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    53   1e-06
gi|148612838 hypothetical protein LOC158358 [Homo sapiens]             52   2e-06
gi|56549696 E1A binding protein p400 [Homo sapiens]                    52   3e-06
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    51   3e-06
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    51   3e-06
gi|239749213 PREDICTED: mucin 3B, cell surface associated, parti...    51   4e-06
gi|169217460 PREDICTED: similar to Mucin-6, partial [Homo sapiens]     50   6e-06
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               50   8e-06
gi|148792970 TAF4b RNA polymerase II, TATA box binding protein (...    50   8e-06
gi|24429588 zinc finger protein 532 [Homo sapiens]                     49   1e-05
gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo sap...    49   2e-05
gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sap...    48   3e-05

>gi|169234719 lin-54 homolog isoform a [Homo sapiens]
          Length = 749

 Score = 1479 bits (3830), Expect = 0.0
 Identities = 749/749 (100%), Positives = 749/749 (100%)

Query: 1   MEVVPAEVNSLLPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATP 60
           MEVVPAEVNSLLPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATP
Sbjct: 1   MEVVPAEVNSLLPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATP 60

Query: 61  ISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKV 120
           ISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKV
Sbjct: 61  ISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKV 120

Query: 121 SQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPP 180
           SQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPP
Sbjct: 121 SQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPP 180

Query: 181 QQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGP 240
           QQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGP
Sbjct: 181 QQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGP 240

Query: 241 VITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNST 300
           VITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNST
Sbjct: 241 VITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNST 300

Query: 301 TQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHY 360
           TQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHY
Sbjct: 301 TQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHY 360

Query: 361 VRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPI 420
           VRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPI
Sbjct: 361 VRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPI 420

Query: 421 NPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQ 480
           NPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQ
Sbjct: 421 NPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQ 480

Query: 481 LQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNCTKSLCLKLYCDCF 540
           LQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNCTKSLCLKLYCDCF
Sbjct: 481 LQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNCTKSLCLKLYCDCF 540

Query: 541 ANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGKEGESDRRHSKGCN 600
           ANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGKEGESDRRHSKGCN
Sbjct: 541 ANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGKEGESDRRHSKGCN 600

Query: 601 CKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADAAEVRVQQQTAAKT 660
           CKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADAAEVRVQQQTAAKT
Sbjct: 601 CKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADAAEVRVQQQTAAKT 660

Query: 661 KLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQADKKGKSKAAAER 720
           KLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQADKKGKSKAAAER
Sbjct: 661 KLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQADKKGKSKAAAER 720

Query: 721 MILEEFGRCLMSVINSAGKAKSDPCAMNC 749
           MILEEFGRCLMSVINSAGKAKSDPCAMNC
Sbjct: 721 MILEEFGRCLMSVINSAGKAKSDPCAMNC 749


>gi|169234723 lin-54 homolog isoform b [Homo sapiens]
          Length = 528

 Score = 1047 bits (2707), Expect = 0.0
 Identities = 521/522 (99%), Positives = 522/522 (100%)

Query: 228 QIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITI 287
           +IAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITI
Sbjct: 7   EIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITI 66

Query: 288 SESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPN 347
           SESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPN
Sbjct: 67  SESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPN 126

Query: 348 VQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIV 407
           VQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIV
Sbjct: 127 VQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIV 186

Query: 408 SAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGN 467
           SAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGN
Sbjct: 187 SAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGN 246

Query: 468 VGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNC 527
           VGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNC
Sbjct: 247 VGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNC 306

Query: 528 TKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGK 587
           TKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGK
Sbjct: 307 TKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGK 366

Query: 588 EGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADA 647
           EGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADA
Sbjct: 367 EGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADA 426

Query: 648 AEVRVQQQTAAKTKLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQ 707
           AEVRVQQQTAAKTKLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQ
Sbjct: 427 AEVRVQQQTAAKTKLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQ 486

Query: 708 ADKKGKSKAAAERMILEEFGRCLMSVINSAGKAKSDPCAMNC 749
           ADKKGKSKAAAERMILEEFGRCLMSVINSAGKAKSDPCAMNC
Sbjct: 487 ADKKGKSKAAAERMILEEFGRCLMSVINSAGKAKSDPCAMNC 528


>gi|169234721 lin-54 homolog isoform b [Homo sapiens]
          Length = 528

 Score = 1047 bits (2707), Expect = 0.0
 Identities = 521/522 (99%), Positives = 522/522 (100%)

Query: 228 QIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITI 287
           +IAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITI
Sbjct: 7   EIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITI 66

Query: 288 SESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPN 347
           SESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPN
Sbjct: 67  SESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPN 126

Query: 348 VQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIV 407
           VQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIV
Sbjct: 127 VQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIV 186

Query: 408 SAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGN 467
           SAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGN
Sbjct: 187 SAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGN 246

Query: 468 VGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNC 527
           VGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNC
Sbjct: 247 VGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNC 306

Query: 528 TKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGK 587
           TKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGK
Sbjct: 307 TKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGK 366

Query: 588 EGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADA 647
           EGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADA
Sbjct: 367 EGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADA 426

Query: 648 AEVRVQQQTAAKTKLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQ 707
           AEVRVQQQTAAKTKLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQ
Sbjct: 427 AEVRVQQQTAAKTKLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQ 486

Query: 708 ADKKGKSKAAAERMILEEFGRCLMSVINSAGKAKSDPCAMNC 749
           ADKKGKSKAAAERMILEEFGRCLMSVINSAGKAKSDPCAMNC
Sbjct: 487 ADKKGKSKAAAERMILEEFGRCLMSVINSAGKAKSDPCAMNC 528


>gi|40806200 metallothionein-like 5, testis-specific isoform a [Homo
           sapiens]
          Length = 508

 Score =  249 bits (637), Expect = 5e-66
 Identities = 136/287 (47%), Positives = 173/287 (60%), Gaps = 42/287 (14%)

Query: 461 PAPGTGNVGYAVLPAQ----YVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSE 516
           P P T  VG   LPA      +TQ  + +  S+ + S F   S +    ++   G     
Sbjct: 253 PKPMTALVG-RFLPASTKLNLITQQLEGALPSVVNGSAFPSGSTLPGPPKITLAG----- 306

Query: 517 SASRPRKPCNCTKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNP 576
                              YCDCFA+G+FCNNCNC NC NNL H+ ER KAIKACL RNP
Sbjct: 307 -------------------YCDCFASGDFCNNCNCNNCCNNLHHDIERFKAIKACLGRNP 347

Query: 577 EAFKPKIGKGKEGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESP 636
           EAF+PKIGKG+ G    +H+KGCNC+RSGCLKNYCECYEA+IMCSSICKCIGCKN+EESP
Sbjct: 348 EAFQPKIGKGQLGNVKPQHNKGCNCRRSGCLKNYCECYEAQIMCSSICKCIGCKNYEESP 407

Query: 637 ERKTLMHLADAAEVRVQQQT--AAKTKLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVA 694
           ERKTLM + +  +    + +     TK S           P  +    + P + ++ EV 
Sbjct: 408 ERKTLMSMPNYMQTGGLEGSHYLPPTKFSG---------LPRFSH--DRRPSSCISWEVV 456

Query: 695 EATCNCLLAQAEQADKKGKSKAAAERMILEEFGRCLMSVINSAGKAK 741
           EATC CLLAQ E+A+K+  SK  AE+MILEEFGRCL  ++++  K+K
Sbjct: 457 EATCACLLAQGEEAEKEHCSKCLAEQMILEEFGRCLSQILHTEFKSK 503


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 126/568 (22%), Positives = 190/568 (33%), Gaps = 107/568 (18%)

Query: 36   SPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAF 95
            +PI   T +       ST  +T TPI+T   TV    T       T T   + TTV P  
Sbjct: 1314 TPITTTTTVTPTPTPTSTQSTTPTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPT- 1371

Query: 96   PSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLA 155
            P+     G QTP T          ++ T+ +     T  P G                  
Sbjct: 1372 PT---PTGTQTPTT--------TPITTTTTV---TPTPTPTG------------------ 1399

Query: 156  LPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINT--T 213
               +Q P +  +TT         P       T    P   P+   + +TP      T   
Sbjct: 1400 ---TQTPTSTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQAP 1449

Query: 214  TQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVL 273
            T  ++  T  +         +TPT+ P+ T         +  VT   T           +
Sbjct: 1450 TPTAITTTSTVTPTPTPTGTQTPTTTPITT---------TTTVTPTPTPTGTQTPTPTAI 1500

Query: 274  SQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVST 333
            + +T  TP+ T T +++        +TT TP     +  ++P     ST  T+T     T
Sbjct: 1501 TTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTP-TGTQTPTPTPISTTTTVTPTPTPT 1559

Query: 334  -SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAK 391
             +Q  T  P+ T   V     P G++     L+T T+  + T   +   ST   P+    
Sbjct: 1560 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTT 1619

Query: 392  PVVVNTTPVRMSVP-IVSAQAVKQVVPKPINPTSQI-------------VTTSQPQQRLI 437
             V    TP     P ++       V P P   T                +TTS P     
Sbjct: 1620 TVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESS 1679

Query: 438  MPAT------PLPQIQPNLTNLPPG---TVLAP-----APGTGNVGYAVLPAQYVTQLQQ 483
             P T      PL +    L+ LPP    T  AP     AP T + G+ + P    T    
Sbjct: 1680 TPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT---- 1735

Query: 484  SSYVSIASNSTFTGTSGIQTQARL-----------PFNGIIPSESASRPRKPCNCTKSLC 532
            +S     +  T TG+S   T + +           P     PS   +   +P   +  +C
Sbjct: 1736 TSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLIC 1795

Query: 533  LKLYCDCFA------NGEFCNNCNCTNC 554
              L    +A      NG + + C   NC
Sbjct: 1796 CVLNDTYYAPGEEVYNGTYGDTCYFVNC 1823



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 75/347 (21%), Positives = 110/347 (31%), Gaps = 53/347 (15%)

Query: 208  QLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPV 267
            Q     TQP+ + T   +          PT  P+ T         +  VT   T  S   
Sbjct: 1292 QCCECVTQPTTMTTTTTEN---------PTPTPITT---------TTTVTPTPTPTSTQS 1333

Query: 268  IAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAI---SPLKSPNKAVKSTVQ 324
                 ++ +T  TP+ T T +++        +TT TP        +P  +P     +   
Sbjct: 1334 TTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1393

Query: 325  TITVGGVST--------------------SQFKTIIPLATAPNVQQIQVP-GSKFHYVRL 363
            T T  G  T                    +Q  T  P+ T   V     P G++      
Sbjct: 1394 TPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTA 1453

Query: 364  VTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPT 423
            +T TS  + T   +   +  T P+     V    TP     P  +A      V     PT
Sbjct: 1454 ITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPT 1513

Query: 424  SQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQ 483
                 TS        P T    + P  T  P GT   P P   +    V P    T  Q 
Sbjct: 1514 GTQTPTS-------TPITTTTTVTP--TPTPTGT-QTPTPTPISTTTTVTPTPTPTGTQT 1563

Query: 484  SSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNCTKS 530
             +   I + +T T T    T  + P   +I + +   P      TKS
Sbjct: 1564 PTTTPITTTTTVTPTP-TPTGTQTPTTVLITTTTTMTPTPTPTSTKS 1609



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 69/283 (24%), Positives = 96/283 (33%), Gaps = 25/283 (8%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            S+PI   T +        T   T TPIST   TV    T       T T   + TTV P 
Sbjct: 1520 STPITTTTTVTPTPTPTGTQTPTPTPIST-TTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1578

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T+          + T                 +  T   +G+    
Sbjct: 1579 -PT---PTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPT 1634

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
             +P S         T         PP       I       P     + TP  Q   +T+
Sbjct: 1635 MIPISTTTTVTPTPTPTTGSTG--PPTHTSTAPIAELTTSNP--PPESSTP--QTSRSTS 1688

Query: 215  QPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLS 274
             P    T  L T+  A +  T T+ P       + P      +G  T   PP       +
Sbjct: 1689 SPLTESTTLLSTLPPAIE-MTSTAPP-------STPTAPTTTSGGHTLSPPP-----STT 1735

Query: 275  QSTPGTPSK-TITISESGVIGSTLNSTTQTPNKIAISPLKSPN 316
             S PGTP++ T T S S    ST+ +TT +      +PL +P+
Sbjct: 1736 TSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPS 1778



 Score = 36.6 bits (83), Expect = 0.088
 Identities = 69/307 (22%), Positives = 100/307 (32%), Gaps = 28/307 (9%)

Query: 33   IVSSPIPMETELEEIVNINSTGDSTATPISTE-PITVYSNHTNQVAVNTTITKADSNTTV 91
            +  +P P  T+    V I +T   T TP  T    T  +  T    V  T T   + T  
Sbjct: 1575 VTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPT 1634

Query: 92   KPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSP 151
                 +        TP T S         +  ++L   N    P  +     T   + SP
Sbjct: 1635 MIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSN----PPPESSTPQTSRSTSSP 1690

Query: 152  IVLALP-HSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLI 210
            +  +    S LP A ++T+ A       P       T  G   + P    +   PG+   
Sbjct: 1691 LTESTTLLSTLPPAIEMTSTAPPSTPTAP------TTTSGGHTLSPPPSTTTSPPGTPTR 1744

Query: 211  NTTTQPS---VLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAV---TGQTTQVS 264
             TTT  S      T Q  T        TP S P I +    +P  S  +       T  +
Sbjct: 1745 GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYA 1804

Query: 265  PPVIAGRVLSQSTPGTPSKTITISESGVIG------STLNSTTQTPNKIAISPLKSPNKA 318
            P    G  +   T G     +  S S  +        +  S T TP+K   +P K  +  
Sbjct: 1805 P----GEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTP 1860

Query: 319  VKSTVQT 325
             K T  T
Sbjct: 1861 SKPTPGT 1867


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 115/477 (24%), Positives = 186/477 (38%), Gaps = 73/477 (15%)

Query: 35  SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTIT----KADSNTT 90
           S+ IP  T  E    + S   ST    S+E IT+    T  V ++T +T     + S TT
Sbjct: 203 STTIPKSTNSEGSTPLTSMPASTMKVASSEAITLL---TTPVEISTPVTISAQASSSPTT 259

Query: 91  VKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGS 150
            +    S     G  TP+T     ++L   S+ S L                TT   +  
Sbjct: 260 AEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLS---------------TTPAATNI 304

Query: 151 PIVLALPHSQLPQAQKVTTQAQSG--DAKLPPQQIKVVTIGGRPEVKPVIGVSALTP--G 206
           P++ +   S  P   + T+   S   +   P       T+   P     +   ++TP   
Sbjct: 305 PVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTM---PVATSEMSTLSITPVDT 361

Query: 207 SQLINTTTQPSVLQTQQLKTVQIAK---KPRTP-TSGPVITKLIFAKPINSKAVTGQTTQ 262
           S L+ T+T+PS L T    T  +     +  TP T+ PV T L+     +S+A T  T  
Sbjct: 362 STLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILV----ASSEASTTSTIP 417

Query: 263 VSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKST 322
           V            S+  T ++  +I+ S     +  ST  T   ++ +P+ S   +  ST
Sbjct: 418 VDSKTFVTTASEASSSPTTAEDTSIATST---PSEGSTPLTSMPVSTTPVASSEASNLST 474

Query: 323 VQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPST 382
               +   V+TS   +  P    P  +   +P          T+T +  ST   S   S 
Sbjct: 475 TPVDSKTQVTTSTEASSSP----PTAEVNSMP----------TSTPSEGSTPLTSM--SV 518

Query: 383 NTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATP 442
           +T P+  ++   ++TTPV  S P+ ++    +       P    + TS P +     +TP
Sbjct: 519 STMPVASSEASTLSTTPVDTSTPVTTS---SEASSSSTTPEGTSIPTSTPSE----GSTP 571

Query: 443 LPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTS 499
                  LTN+P  T L  +        +  PA   T +  SS  S +S++T  GTS
Sbjct: 572 -------LTNMPVSTRLVVSSEASTT--STTPADSNTFVTTSSEAS-SSSTTAEGTS 618



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 104/538 (19%), Positives = 215/538 (39%), Gaps = 66/538 (12%)

Query: 3    VVPAEVNSLLPEEI-MDTGITLVDDDSIEAVIVS-SPIPMETELEEIVNINSTGDSTATP 60
            VV +E ++L    +   T +T   + S+       + IP  +  E    + S   ST   
Sbjct: 3352 VVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPV 3411

Query: 61   ISTEPITVYSNHTNQVAVNTTITKADSNTTVKP--AFPSGLQKLGAQTPVTISANQIILN 118
            +S+E  T+ +   +   + TT T+A S+ T+    + P+     G+ TP++I        
Sbjct: 3412 VSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGS-TPLSI-------- 3462

Query: 119  KVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQS--GDA 176
                   + L    +       + TT   + +P+  + P +  P   +VT+   S  G+ 
Sbjct: 3463 -------MPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEG 3515

Query: 177  KLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTP 236
              P   + V T          +  + +   + + +++   S   T Q+ T++++    TP
Sbjct: 3516 STPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMS----TP 3571

Query: 237  TSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGST 296
            + G                    ++ ++  +++   ++ S   TPS       + V  ST
Sbjct: 3572 SEG--------------------SSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTST 3611

Query: 297  LNSTTQTPNKIAISPLKSPNKA--------VKSTVQTITVGGV-STSQFKTIIPLATAPN 347
             +++T TP ++   P+ +P++         V +T  TI+  G  ST    T  P+ T+  
Sbjct: 3612 QSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQ 3671

Query: 348  VQQIQV-PGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPI 406
            V    V P      +   +  S   +T PVS    T+++    + P VV +TPV  S   
Sbjct: 3672 VSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEA 3731

Query: 407  VSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTG 466
            +S+ A        ++   +I T       +++  TP+ +   + T   P    + +  T 
Sbjct: 3732 ISSSATLDSTTMSVSMPMEISTLG---TTILVSTTPVTRFPESSTPSIPSVYTSMSMTTA 3788

Query: 467  NVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKP 524
            + G     +   T L+ ++  ++  ++T   ++ + T    P + + PSE+++    P
Sbjct: 3789 SEG-----SSSPTTLEGTT--TMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPP 3839



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 106/488 (21%), Positives = 184/488 (37%), Gaps = 74/488 (15%)

Query: 1    MEVVPAEVNSLLPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNI-NSTGDSTAT 59
            + ++P     +   E      T VD  +   V  SSP        E+ ++  ST    +T
Sbjct: 3460 LSIMPLSTTPVASSEASTLSTTPVDTST--PVTTSSPTNSSPTTAEVTSMPTSTAGEGST 3517

Query: 60   PISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNK 119
            P++  P++     +++ +  +T T  DSNT V  +  +      + +P T+   Q+   +
Sbjct: 3518 PLTNMPVSTTPVASSEASTLST-TPVDSNTFVTSSSQA------SSSPATL---QVTTMR 3567

Query: 120  VSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLP 179
            +S  S+   G+ +L          T  ++ +P   ++  S       VTT  QS     P
Sbjct: 3568 MSTPSE---GSSSLTTMLLSSTYVTSSEASTPSTPSVDRST-----PVTTSTQSNSTPTP 3619

Query: 180  PQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSG 239
            P+               VI +   TP       T  P    +  +     A      TS 
Sbjct: 3620 PE---------------VITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTST 3664

Query: 240  PVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNS 299
            PVIT    +  ++S  VT + T +        + + S   TP  T+ +S + V  S   S
Sbjct: 3665 PVIT----STQVSSSPVTPEGTTMP-------IWTPSEGSTPLTTMPVSTTRVTSSE-GS 3712

Query: 300  TTQTPNKIAISPLKSPNKAVKS--TVQTITVG---GVSTSQFKTIIPLATAPNVQ--QIQ 352
            T  TP+ +  +P+ +  +A+ S  T+ + T+     +  S   T I ++T P  +  +  
Sbjct: 3713 TLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESS 3772

Query: 353  VPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAV 412
             P     Y  +   T++  S+ P +    T T P+          T V +S   V + + 
Sbjct: 3773 TPSIPSVYTSMSMTTASEGSSSPTTLE-GTTTMPMSTTSERSTLLTTVLISPISVMSPSE 3831

Query: 413  KQVVPKPINPTSQIVTTSQPQQRLIMPA--------------TPLPQIQPNLTNLP---P 455
               +  P   TS  + TS       +PA              TPL  +  + T LP   P
Sbjct: 3832 ASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVS-TTLPTSFP 3890

Query: 456  GTVLAPAP 463
            G  +A  P
Sbjct: 3891 GASIASTP 3898



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 101/459 (22%), Positives = 174/459 (37%), Gaps = 83/459 (18%)

Query: 12   LPEEIMDTGITLVDDDSIEAVIVSSP-------IPMETELEEIVNINSTGDSTATPISTE 64
            LP      G TL+    +   +V+SP        P++T+   + +   +   T    ++ 
Sbjct: 1268 LPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSM 1327

Query: 65   PITVYSNHTN---QVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVS 121
            P + YS        + VNTT+  A S  ++    P     +   TPVT S         S
Sbjct: 1328 PTSTYSEGRTPLTSIPVNTTLV-ASSAISILSTTP-----VDNSTPVTTSTEACSSPTTS 1381

Query: 122  QTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQ 181
            + + +   N    P      LT++  S +P+V          ++  T  A   D   P  
Sbjct: 1382 EGTSMPNSN----PSEGTTPLTSIPVSTTPVV---------SSEASTLSATPVDTSTPGT 1428

Query: 182  QIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPV 241
                 T             S+ T    +   T+ PS  +T  LK++ ++  P   +    
Sbjct: 1429 TSAEAT-------------SSPTTAEGISIPTSTPSEGKTP-LKSIPVSNTPVANSEAST 1474

Query: 242  ITKLIFAKPI--NSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTIT---ISESGVIGST 296
            ++      P+  NS  VT      SP    G  ++ STP   S  +T   +S + V  S 
Sbjct: 1475 LS----TTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSE 1530

Query: 297  LNSTTQTPNKIAISPL-------KSPNKAVKSTVQTITVGGVSTS----QFKTIIPLATA 345
            +NS + TP  +  +P+        SP  A  +++QT T    ST        T++ +++ 
Sbjct: 1531 INSLSTTP-AVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSE 1589

Query: 346  PNVQQIQVPGSKFHYVRLVTATSASSST---------------QPVSQNPSTNTQPLQQA 390
             N        SK    ++  +T ASSST                P+  +   +T P+   
Sbjct: 1590 ANTLSTTPIDSK---TQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASP 1646

Query: 391  KPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTT 429
            +   ++TTPV  + P++++  V    P P   TS   +T
Sbjct: 1647 EASTLSTTPVDSNSPVITSTEVSS-SPTPAEGTSMPTST 1684



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 111/519 (21%), Positives = 190/519 (36%), Gaps = 40/519 (7%)

Query: 6    AEVNSLLPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEP 65
            A + S  P +      T  +  S       + +P  T  E    + S   ST T  S+E 
Sbjct: 3239 ASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSET 3298

Query: 66   ITVYSNHTNQVAVNTTITKADSNTTVKP--AFPSGLQKLGAQTPVT---ISANQIILNKV 120
             T+ +   +     TT ++A S+  +    + P+     G+ TP+T    S   ++ ++ 
Sbjct: 3299 STLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGS-TPLTNMSFSTTPVVSSEA 3357

Query: 121  SQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPH---SQLPQAQKVTTQAQSGDAK 177
            S  S   +   T      +  L+     G+ I  + P    + L      TT   S +  
Sbjct: 3358 STLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVN 3417

Query: 178  L----PPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSV--LQTQQLKTVQIAK 231
                 P     +VT        P I      P S     +T  S+  L T  + + + + 
Sbjct: 3418 TLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEAST 3477

Query: 232  KPRTP--TSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISE 289
               TP  TS PV T    + P NS   T + T + P   AG     STP T     T   
Sbjct: 3478 LSTTPVDTSTPVTT----SSPTNSSPTTAEVTSM-PTSTAGE---GSTPLTNMPVSTTPV 3529

Query: 290  SGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVS--TSQFKTIIPLATAPN 347
            +    STL++T    N    S  ++ +      V T+ +   S  +S   T++  +T   
Sbjct: 3530 ASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVT 3589

Query: 348  VQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIV 407
              +   P +          TS  S++ P    P   T P+     V    T + +S   V
Sbjct: 3590 SSEASTPSTPSVDRSTPVTTSTQSNSTPTP--PEVITLPMSTPSEVSTPLTIMPVSTTSV 3647

Query: 408  SAQAVKQVVPKPINPTSQIVTTSQPQQRLIMP-ATPLPQIQPN-----LTNLPPGTVLAP 461
            +          P++ ++ ++T++Q     + P  T +P   P+     LT +P  T    
Sbjct: 3648 TISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRV- 3706

Query: 462  APGTGNVGYAVLPAQYVTQLQ-QSSYVSIASNSTFTGTS 499
               T + G  +     VT     +S  +I+S++T   T+
Sbjct: 3707 ---TSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTT 3742



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 114/515 (22%), Positives = 192/515 (37%), Gaps = 89/515 (17%)

Query: 38   IPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVK----- 92
            +P  T  E    + S   ST   +S+E  T+ +   +     TT T+A S+ T       
Sbjct: 1091 MPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSI 1150

Query: 93   PAFPSG-----LQKLGAQTPVTIS--ANQIILNKVSQTSDLKLGNQTLKP----DGQKLI 141
            P  P       L  +   T + +S  AN +    V   + +    +   P    +   + 
Sbjct: 1151 PTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMP 1210

Query: 142  LTTLGKSGSPIV-LALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGV 200
             +T G+  +P+  + + H+ +  ++  T      D   P      VT        P    
Sbjct: 1211 TSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTP------VTTSAETSSSPTTAE 1264

Query: 201  SALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPR------TP--TSGPVITKL-IFAKPI 251
                P S    TT++ S L T    +  +   P       TP  T GPV+T   + + P 
Sbjct: 1265 GTSLPTS----TTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPT 1320

Query: 252  NSKAVT--------GQTTQVSPPV----IAGRVLS--QSTPGTPSKTITISESGVIGSTL 297
             ++  +        G+T   S PV    +A   +S   +TP   S  +T S       T 
Sbjct: 1321 PAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTT 1380

Query: 298  NSTTQTPNKI---AISPLKS----PNKAVKSTVQTITVGGVSTSQFKTIIPLATAP--NV 348
            +  T  PN       +PL S        V S   T++   V TS   T    AT+     
Sbjct: 1381 SEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTA 1440

Query: 349  QQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVS 408
            + I +P          T+T +   T P+   P +NT P+  ++   ++TTPV  + P+V+
Sbjct: 1441 EGISIP----------TSTPSEGKT-PLKSIPVSNT-PVANSEASTLSTTPVDSNSPVVT 1488

Query: 409  AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNV 468
            + AV    P P   TS  ++T               +    LT++P  T    +    ++
Sbjct: 1489 STAVSS-SPTPAEGTSIAISTPS-------------EGSTALTSIPVSTTTVASSEINSL 1534

Query: 469  GYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQT 503
              +  PA  VT    ++Y   +S+ T    + +QT
Sbjct: 1535 --STTPA--VTSTPVTTYSQASSSPTTADGTSMQT 1565



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 104/449 (23%), Positives = 177/449 (39%), Gaps = 56/449 (12%)

Query: 35   SSPIPMETELEEI-VNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKP 93
            S+P    T L  I V+     +S A+ +ST P+   +  T     +++ T A+  T+++ 
Sbjct: 2685 STPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEG-TSMRI 2743

Query: 94   AFPSG----LQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSG 149
            + PS     L  +   T    S+    ++  +  + + +   T           T   + 
Sbjct: 2744 STPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTS 2803

Query: 150  SPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKV-VTIGGRPEVKPVIGVSALTPGSQ 208
            +P   + P + +P        +++G     P      VT   +    P      + P   
Sbjct: 2804 TPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVP--- 2860

Query: 209  LINTTTQPSVLQTQ-QLKTVQIAK-KPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPP 266
             I+T ++ S L T   + T  +A  +  T ++ PV T +          VT  T   S P
Sbjct: 2861 -ISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSI---------PVTTSTEGSSSP 2910

Query: 267  VIA-GRVLSQSTPG---TPSKTITISESGVIGS---TLNST---TQTPNKIAISPLKSPN 316
              A G  +  STP    TP  +I +S   V GS   TL++T   T+TP   +     SP 
Sbjct: 2911 TTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPT 2970

Query: 317  KAVKSTVQTITVGGVST---SQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSST 373
             A  +++   T G   T   S   + +P+A++      + P      V   T  S+S +T
Sbjct: 2971 TAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTT 3030

Query: 374  Q-----PVSQNPSTNTQPLQQ----AKPVVV------NTTPVRMSVPIVSAQAVKQVVPK 418
                  P+S  PS  + PL        PV +      +TTPV  + P+V++  V    P 
Sbjct: 3031 AEGTGIPIS-TPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSS-SPT 3088

Query: 419  PINPTSQIVTT----SQPQQRLIMPATPL 443
            P   TS  ++T    S P   + +  TP+
Sbjct: 3089 PAEGTSMPISTYSEGSTPLTGVPVSTTPV 3117



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 96/502 (19%), Positives = 191/502 (38%), Gaps = 54/502 (10%)

Query: 22   TLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTT 81
            T  +  S+     S   P+ T +   V+I       A+ +ST P+   S  T    V+++
Sbjct: 789  TTTEGTSMPISTPSEGSPLLTSIP--VSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSS 846

Query: 82   ITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLI 141
             T A+  +     +  G   L   T + +S   +  + +S  S   +   T   +  +  
Sbjct: 847  PTPAEGTSMPTSTYSEGRTPL---TSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEAR 903

Query: 142  LTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVS 201
             +     G+ +  + P       +  T      D+  P    +  T+   P       V 
Sbjct: 904  SSPTTSEGTSMPTSTP------GEGSTPLTSMPDSTTPVVSSEARTLSATP-------VD 950

Query: 202  ALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIF--------AKPINS 253
              TP +     T+ P+  +   + T   ++     TS PV   L+           P++S
Sbjct: 951  TSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDS 1010

Query: 254  KAVTGQTTQVS--PPVIAGRVLSQSTPGTPSKTIT---ISESGVIGSTLNSTTQTPNKIA 308
                  +T+ S  PP   G  +  STP   S  +T   +S + V  S  ++ + TP   +
Sbjct: 1011 NTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTS 1070

Query: 309  ISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQV--PGSKFHYVRLVTA 366
             +P+ + ++A  S+         +++  +   PL + P   ++ V    S      + T+
Sbjct: 1071 -TPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTS 1129

Query: 367  TSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVR---MSVPIVSAQAVKQVVPKPINPT 423
               ++ST+  S +P+T         P    TTP+    +S  +V +     +   P++  
Sbjct: 1130 IPVTTSTE-ASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSK 1188

Query: 424  SQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQ 483
            +Q+ T+++        ++P P  +  +T++P  T     PG  +     +P ++      
Sbjct: 1189 TQVATSTE-------ASSPPPTAE--VTSMPTST-----PGERSTPLTSMPVRHTP--VA 1232

Query: 484  SSYVSIASNSTFTGTSGIQTQA 505
            SS  S  S S    ++ + T A
Sbjct: 1233 SSEASTLSTSPVDTSTPVTTSA 1254



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 120/535 (22%), Positives = 194/535 (36%), Gaps = 104/535 (19%)

Query: 38   IPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKP--AF 95
            +P  T  E    + S   ST   +S+E  T+ +   +     TT T+A S+ T     + 
Sbjct: 1739 MPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSI 1798

Query: 96   PSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLA 155
            P+     G  TP+T +     L   S+ S L                TT   S SP+V +
Sbjct: 1799 PTSTLSEG-MTPLTSTPVSHTLVANSEASTLS---------------TTPVDSNSPVVTS 1842

Query: 156  LPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINT-TT 214
               S  P   + T+ A S     P +    +T          I VS  T  S   NT +T
Sbjct: 1843 TAVSSSPTPAEGTSIATS----TPSEGSTALTS---------IPVSTTTVASSETNTLST 1889

Query: 215  QPSVLQTQQLKTVQIAKKPRTP-----------------TSGPVITKLIFAKPINSKAVT 257
             P+V  T      Q++  P T                  TS PV T  + +  IN+ + T
Sbjct: 1890 TPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTT 1949

Query: 258  GQTTQV----------SPPVIAGRVL---SQSTPGTPSKTITISESGVIGS---TLNST- 300
               T+           SP    G  +   + S   TP  ++ +S + V+ S   TL++T 
Sbjct: 1950 LADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTP 2009

Query: 301  --TQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTS----QFKTIIPLATAPNVQQIQVP 354
              T TP   +     SP  A  +++QT T    +T        T + +++  N       
Sbjct: 2010 VDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPV 2069

Query: 355  GSKFHYVRLVTATS------------ASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRM 402
             SK        A+S            A S   P+  +   +T P+   +   ++TTPV  
Sbjct: 2070 DSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDS 2129

Query: 403  SVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPA 462
            + P++++  V    P P   TS   +T   ++      TP       LT++P  T +  +
Sbjct: 2130 NSPVITSTEVSS-SPIPTEGTSMQTSTYSDRR------TP-------LTSMPVSTTVVAS 2175

Query: 463  PGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSES 517
                 +  +  P    T +  S+     + S+ T + G       P  G  P  S
Sbjct: 2176 SAISTL--STTPVDTSTPVTNST----EARSSPTTSEGTSMPTSTPSEGSTPFTS 2224



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 114/532 (21%), Positives = 200/532 (37%), Gaps = 77/532 (14%)

Query: 28   SIEAVIVSSPIPMETELEEIVNINSTGDSTATPIST-----EPIT-VYSNHT---NQVAV 78
            S   V  S+P+   TE     +  +T + T+ P ST      P+T +  +HT   N    
Sbjct: 2241 SATPVDTSTPVTTSTEA---TSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVS 2297

Query: 79   NTTITKADSNT----TVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLK 134
              + T  DSNT    + + + P    +  +    T S     L ++  ++ +    +T  
Sbjct: 2298 TLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFET-- 2355

Query: 135  PDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQS--GDAKLPPQQIKVVTIGGRP 192
                  + TT   + +P+         P     T+   S   +   P   + V T+    
Sbjct: 2356 ----STLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTM---- 2407

Query: 193  EVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVI-TKLIFAKPI 251
               PV+   A T  +  ++T+T P    T+   +   A+    PTS P   T  + + P+
Sbjct: 2408 ---PVVSSEASTHSTTPVDTST-PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPV 2463

Query: 252  NSKAVTGQT--TQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLN--STTQTPNKI 307
            ++  V      T  + PV     ++ ST  + S T T  +  V  ST +  ST  T   +
Sbjct: 2464 STTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPT-TAEDIVVPISTASEGSTLLTSIPV 2522

Query: 308  AISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTAT 367
            + +P+ SP  +  ST    +   V TS               +I    +      + T+T
Sbjct: 2523 STTPVASPEASTLSTTPVDSNSPVVTST--------------EISSSATSAEGTSMPTST 2568

Query: 368  SASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIV------SAQAVKQVVPKPIN 421
             +  ST P+   P  +T+PL  ++   ++TTPV  S+P+       S+    +    PI+
Sbjct: 2569 YSEGST-PLRSMP-VSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPIS 2626

Query: 422  PTSQIVTTSQPQQRLIMPA--------TPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVL 473
              S++ T+        MP         +  P     L     GT  +P    G+      
Sbjct: 2627 TPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTST 2686

Query: 474  PAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIP----SESASRP 521
            P +  T L      +I  ++T    S   T +  P +   P    +E++S P
Sbjct: 2687 PGERSTPL-----TNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSP 2733



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 118/529 (22%), Positives = 203/529 (38%), Gaps = 88/529 (16%)

Query: 33   IVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVK 92
            I+ S +P+ +   E   +++T   T+ P++T      S  T +V    T T ++++T + 
Sbjct: 2756 ILVSTLPVASS--EASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLT 2813

Query: 93   PAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPI 152
             + P     + +    T+S   +  +    TS  K  +     +G  + ++T  + GS +
Sbjct: 2814 -SMPVNHTPVASSEAGTLSTTPVDTSTPVTTST-KASSSPTTAEGIVVPISTASE-GSTL 2870

Query: 153  VLALPHSQLPQA--QKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLI 210
            + ++P S  P A  +  T      D  +P      VT        P        P    I
Sbjct: 2871 LTSIPVSTTPVASSEASTLSTTPVDTSIP------VTTSTEGSSSPTTAEGTSMP----I 2920

Query: 211  NTTTQPSVLQTQQL-KTVQIA-KKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVI 268
            +T ++ S   T  L  TV +A  +  T ++ PV T+     P+ + A        SP   
Sbjct: 2921 STPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRT----PVTTSAEASS----SPTTA 2972

Query: 269  AGRVLSQSTPG---TPSKTITISESGVIGS---TLNST---TQTPNKIAISPLKSPNKAV 319
             G  +  STPG   TP  ++++S   V  S   TL+ T   T TP   +     SP  A 
Sbjct: 2973 EGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAE 3032

Query: 320  KSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVR-------LVTATSASSS 372
             + +   T    ST    T IP++T P    + +P +             +VT+T  SSS
Sbjct: 3033 GTGIPISTPSEGSTPL--TSIPVSTTP----VAIPEASTLSTTPVDSNSPVVTSTEVSSS 3086

Query: 373  TQPVS------------QNPST----NTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVV 416
              P                P T    +T P+  +    ++TTPV  S P+ ++    +  
Sbjct: 3087 PTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTS---TEAH 3143

Query: 417  PKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQ 476
              P       + TS P +     +TP       LT +P  T+L  +     +        
Sbjct: 3144 SSPTTSEGTSMPTSTPSE----GSTP-------LTYMPVSTMLVVSSEDSTLS------- 3185

Query: 477  YVTQLQQSSYVSIASNSTFTGTS-GIQTQARLPFNGIIPSESASRPRKP 524
              T +  S+ V+ ++ +T + T+ G       P  G+ P  S      P
Sbjct: 3186 -ATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTP 3233



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 113/542 (20%), Positives = 191/542 (35%), Gaps = 74/542 (13%)

Query: 1   MEVVPAEVNSL--LPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTA 58
           M VV +E ++L   P       IT  +  S       + IP  T  E    + ST  ST 
Sbjct: 285 MLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTM 344

Query: 59  TPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLG-AQTPVT---ISANQ 114
              ++E  T+     +   + TT T+  S  T   A       L    TP+T   +S   
Sbjct: 345 PVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTIL 404

Query: 115 IILNKVSQTSDLKLGNQTLKPDGQKL-----------ILTTLGKSGSPIVLALPHSQLPQ 163
           +  ++ S TS + + ++T      +            I T+    GS  + ++P S  P 
Sbjct: 405 VASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPV 464

Query: 164 AQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQ 223
           A    +   +       Q          P    V  +   TP       T+    + T  
Sbjct: 465 ASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMS--VSTMP 522

Query: 224 LKTVQIAKKPRTP--TSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPG-- 279
           + + + +    TP  TS PV T        +S+A +  TT        G  +  STP   
Sbjct: 523 VASSEASTLSTTPVDTSTPVTT--------SSEASSSSTTP------EGTSIPTSTPSEG 568

Query: 280 -TPSKTITISESGVIGSTLNSTTQTP---------------NKIAISPLKSPNKAVKSTV 323
            TP   + +S   V+ S  ++T+ TP               +         P        
Sbjct: 569 STPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERG 628

Query: 324 QTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTN 383
            TIT   VST    T++  + A  +    V  S         ATS+S++ +  S   ST 
Sbjct: 629 TTITSMSVST----TLVASSEASTLSTTPVD-SNTPVTTSTEATSSSTTAEGTSMPTSTY 683

Query: 384 TQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQR------LI 437
           T+       + VNTT       +V++     +   P++ ++ + T+++            
Sbjct: 684 TEGSTPLTSMPVNTT-------LVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGAS 736

Query: 438 MPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTG 497
           MP +   +    LT++P    L  +     +  +  P    T +  S+  S  S +T  G
Sbjct: 737 MPTSTPSEGSTPLTSMPVSKTLLTSSEASTL--STTPLDTSTHITTSTEAS-CSPTTTEG 793

Query: 498 TS 499
           TS
Sbjct: 794 TS 795



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 108/515 (20%), Positives = 192/515 (37%), Gaps = 77/515 (14%)

Query: 4    VPAEVNSLLPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTAT---- 59
            +P     +   E      T VD +S   V+ S+ I       E  ++ ++  S  +    
Sbjct: 2520 IPVSTTPVASPEASTLSTTPVDSNS--PVVTSTEISSSATSAEGTSMPTSTYSEGSTPLR 2577

Query: 60   --PISTEPITVYSNHT-------NQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTI 110
              P+ST+P+      T         + V T+   + S TT K         +   + V+ 
Sbjct: 2578 SMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTS----MPISTPSEVST 2633

Query: 111  SANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQ 170
            S   I+++ +   S       T   D + L+ T+ G S SP       S +P +      
Sbjct: 2634 SLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAE--GSSMPTSTP---- 2687

Query: 171  AQSGDAKLPPQQIKVVTI---GGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTV 227
               G+   P   I V T               V   TP +     ++ P+  +   ++  
Sbjct: 2688 ---GERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRI- 2743

Query: 228  QIAKKPRTPTSG--PVITKLIFAKPI-NSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKT 284
                   TP+ G  P+ + L+   P+ +S+A T  TT V            S P T S  
Sbjct: 2744 ------STPSDGSTPLTSILVSTLPVASSEASTVSTTAVDT----------SIPVTTSTE 2787

Query: 285  ITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLAT 344
               S S       +  T TP++ + +PL S      + V +   G +ST+   T  P+ T
Sbjct: 2788 A--SSSPTTAEVTSMPTSTPSETS-TPLTSM-PVNHTPVASSEAGTLSTTPVDTSTPVTT 2843

Query: 345  APNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSV 404
            +                 +V  ++AS  +  ++  P  +T P+  ++   ++TTPV  S+
Sbjct: 2844 STKASSSPTTAEGI----VVPISTASEGSTLLTSIP-VSTTPVASSEASTLSTTPVDTSI 2898

Query: 405  PIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPG 464
            P+ ++           +PT+   T+        MP +   ++   LT++   TV  P  G
Sbjct: 2899 PVTTSTEGSS------SPTTAEGTS--------MPISTPSEVSTPLTSILVSTV--PVAG 2942

Query: 465  TGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTS 499
            +     +  P    T +  S+  S +S +T  GTS
Sbjct: 2943 SEASTLSTTPVDTRTPVTTSAEAS-SSPTTAEGTS 2976



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 108/484 (22%), Positives = 185/484 (38%), Gaps = 67/484 (13%)

Query: 22   TLVDDDSIEAVIVSSPIPMETELE---EIVNINSTGDSTATPIS-----TEPITVYSNHT 73
            TLV   +I +++ ++P+   T +    E  +  +T + T+ P S     T P+T     T
Sbjct: 1347 TLVASSAI-SILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVST 1405

Query: 74   NQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQ----TSDLKLG 129
              V  +   T   S T V  + P         +P T     I  +  S+       + + 
Sbjct: 1406 TPVVSSEASTL--SATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVS 1463

Query: 130  NQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQS----GDAKLPPQQIKV 185
            N  +       + TT   S SP+V +   S  P   + T+ A S    G   L    +  
Sbjct: 1464 NTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVST 1523

Query: 186  VTIGGRPEVKPVIGVSALT--PGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVIT 243
             T+    E+  +    A+T  P +     ++ P+      ++T   ++     TS PV T
Sbjct: 1524 TTVASS-EINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVST 1582

Query: 244  KLIFAK--------PINSKA-VTGQTTQVSPPVIAGRVLSQSTP--GTPSKT-ITISESG 291
             L+ +         PI+SK  VT  T   S     G  ++ STP  G+P  T I +S + 
Sbjct: 1583 MLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTP 1642

Query: 292  VIG---STLNSTTQTPNKIAISPLK---SPNKAVKSTVQTITVGGVSTSQFKTIIPLATA 345
            V     STL++T    N   I+  +   SP  A  +++ T T     T    T I + T 
Sbjct: 1643 VASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPL--TSITVRTT 1700

Query: 346  PNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVP 405
            P              +  ++ T   +ST PV+ +    + P       + N+TP   + P
Sbjct: 1701 PVASSA---------ISTLSTTPVDNST-PVTTSTEARSSPTTSEGTSMPNSTPSEGTTP 1750

Query: 406  IVS---------AQAVKQVVPKPINPTSQIVT----TSQP--QQRLIMPATPLPQIQPNL 450
            + S         +     +   PI+ ++ + T    TS P   +   +P + L +    L
Sbjct: 1751 LTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPL 1810

Query: 451  TNLP 454
            T+ P
Sbjct: 1811 TSTP 1814



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 117/549 (21%), Positives = 205/549 (37%), Gaps = 68/549 (12%)

Query: 16   IMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQ 75
            +  T +   +  ++    V + IP+ T  E   +  +T + T+ PIST P  V +  T+ 
Sbjct: 2876 VSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSS-PTTAEGTSMPIST-PSEVSTPLTSI 2933

Query: 76   VAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKP 135
            +   +T+  A S  +     P     +  +TPVT SA        ++ + + +      P
Sbjct: 2934 LV--STVPVAGSEASTLSTTP-----VDTRTPVTTSAEASSSPTTAEGTSMPIST----P 2982

Query: 136  DGQKLILTTLGKSGSPIVLA----LPHSQLPQAQKVTTQAQSGDAKLPPQ----QIKVVT 187
              ++  LT++  S  P+  +    L  +    +  VTT  ++  +    +     I   +
Sbjct: 2983 GERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPS 3042

Query: 188  IGGRPEVK-PVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKL- 245
             G  P    PV       P +  ++TT   S         V  +  P   TS P+ T   
Sbjct: 3043 EGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSE 3102

Query: 246  ---------IFAKPINSKAV-TGQTTQV--------------SPPVIAGRVLSQSTPG-- 279
                     +   P+ S A+ T  TT V              SP    G  +  STP   
Sbjct: 3103 GSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEG 3162

Query: 280  -TPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKT 338
             TP   + +S   V+ S  ++ + TP   + +P+ +  +A  ST    T    ST   + 
Sbjct: 3163 STPLTYMPVSTMLVVSSEDSTLSATPVDTS-TPVTTSTEATSSTTAEGTSIPTSTPS-EG 3220

Query: 339  IIPLATAP--NVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVN 396
            + PL + P  N        S      + + T  ++ST+  S  P+     +  + P   +
Sbjct: 3221 MTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGS 3280

Query: 397  T--TPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQR------LIMPATPLPQIQP 448
            T  T + +S   V++     +   P + ++ + T SQ            MP +   +   
Sbjct: 3281 TPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGST 3340

Query: 449  NLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLP 508
             LTN+   T   P   +     +  P    T +  S+  S+ S +T  GTS I T +  P
Sbjct: 3341 PLTNMSFST--TPVVSSEASTLSTTPVDTSTPVTTSTEASL-SPTTAEGTS-IPTSS--P 3394

Query: 509  FNGIIPSES 517
              G  P  S
Sbjct: 3395 SEGTTPLAS 3403



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 117/536 (21%), Positives = 195/536 (36%), Gaps = 71/536 (13%)

Query: 22   TLVDDDS---IEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAV 78
            T VD +S       + SSP P E       +  S G +  T I     TV S+ TN ++ 
Sbjct: 1831 TPVDSNSPVVTSTAVSSSPTPAEGT-SIATSTPSEGSTALTSIPVSTTTVASSETNTLST 1889

Query: 79   NTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQ 138
               +T     TT      S     G+  P +         +   TS + +   T+     
Sbjct: 1890 TPAVTSTPV-TTYAQVSSSPTTADGSSMPTSTPRE----GRPPLTS-IPVSTTTVASSEI 1943

Query: 139  KLILTTLGKSGSPIVLALPHSQLPQAQKVTTQA----QSGDAKLPPQQIKV-VTIGGRPE 193
              + TTL  + +P+      S  P     T+        G   L    +   + +     
Sbjct: 1944 NTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEAS 2003

Query: 194  VKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSG-PVITKLIFAK--- 249
                  V   TP +     ++ P+      ++T   +++  TP +G PV T L+ +    
Sbjct: 2004 TLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERT-TPLAGMPVSTTLVVSSEGN 2062

Query: 250  -----PINSKA-VTGQTTQVSPPVIAGRVLSQSTP--GTPSKT--------ITISESGVI 293
                 P++SK  VT  T   S     G  ++ S P  G+P  T        +   E+  +
Sbjct: 2063 TLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTL 2122

Query: 294  GST---LNSTTQTPNKIAISPLKSPNKAVKSTVQT-----ITVGGVSTSQFKT--IIPLA 343
             +T    NS   T  +++ SP+ +   +++++  +     +T   VST+   +  I  L+
Sbjct: 2123 STTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLS 2182

Query: 344  TAPNVQQIQVPGSKFHYVRLVTA--TSASSSTQPVSQNPSTN----TQPLQQAKPVVVNT 397
            T P      V  S        T+  TS  +ST      P T+    T P+  ++   ++ 
Sbjct: 2183 TTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSA 2242

Query: 398  TPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGT 457
            TPV  S P+ ++           +PT+    TS P   L    TPL  I  + T +    
Sbjct: 2243 TPVDTSTPVTTSTEATS------SPTT-AEGTSIPTSTLSEGTTPLTSIPVSHTLVANSE 2295

Query: 458  V--LAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIA---SNSTFTGTSGIQTQARLP 508
            V  L+  P   N         + T  + SS    A   S  T T + G     R+P
Sbjct: 2296 VSTLSTTPVDSN-------TPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMP 2344



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 99/454 (21%), Positives = 152/454 (33%), Gaps = 100/454 (22%)

Query: 28   SIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADS 87
            S  +V+ S+P+   TE    ++ ++T DST   +S  P+ + +  T  +   T +T+   
Sbjct: 3715 STPSVVTSTPVTTSTEA---ISSSATLDSTTMSVSM-PMEISTLGTTILVSTTPVTRFPE 3770

Query: 88   NTTVKPAFPSGLQKL-------GAQTPVTISANQ----------------IILNKVSQTS 124
            ++T  P+ PS    +       G+ +P T+                    ++++ +S  S
Sbjct: 3771 SST--PSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMS 3828

Query: 125  DLKLGNQTLKPDGQKLILTTLGKSGS--------------------PIVLALPHSQLPQA 164
              +    +  P      L T  K+GS                    P+   L  + LP +
Sbjct: 3829 PSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTS 3888

Query: 165  QKVTTQAQSGDAKLPPQQIKVVTIGGRPE--VKPVIGVSALTPGSQLINTTTQPSVLQTQ 222
                + A +                  P   V   I VS +T GS    T   PS   T 
Sbjct: 3889 FPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTS 3948

Query: 223  QLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQT------------TQVSPPVIAG 270
               T  +        S PVIT      P  S + T  +            T  +P     
Sbjct: 3949 S--TADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVT 4006

Query: 271  RVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGG 330
               + STP T S+  T S S +   +  ST  T   +   P+   +++ +          
Sbjct: 4007 MSTAPSTPRTTSRGCTTSASTL---SATSTPHTSTSVTTRPVTPSSESSRP--------- 4054

Query: 331  VSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQA 390
             ST    TI P  T P       P            TSASS+T     NP   T    + 
Sbjct: 4055 -STITSHTIPP--TFPPAHSSTPP-----------TTSASSTT----VNPEAVTTMTTRT 4096

Query: 391  KPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTS 424
            KP    T     S P V+  AV        NPTS
Sbjct: 4097 KPSTRTT-----SFPTVTTTAVPTNTTIKSNPTS 4125



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 53/210 (25%), Positives = 81/210 (38%), Gaps = 25/210 (11%)

Query: 220 QTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPG 279
           Q QQL             +G   T ++  +   S +   + T +   V +      ST  
Sbjct: 51  QCQQLSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRM 110

Query: 280 TPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTI 339
           TP+++ T SE     ST +STT  P+  +     SP     + V   T    S S     
Sbjct: 111 TPTESRTTSE-----STSDSTTLFPS--STEDTSSPTTPEGTDVPMSTPSEESISSTMAF 163

Query: 340 IPLATAPNVQQIQVPGSKFHY-VRLVTATSASSS-------TQPVSQNPS---------T 382
           +  A  P+ +       K      L T+T ASSS       T P S N            
Sbjct: 164 VSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPA 223

Query: 383 NTQPLQQAKPVVVNTTPVRMSVPI-VSAQA 411
           +T  +  ++ + + TTPV +S P+ +SAQA
Sbjct: 224 STMKVASSEAITLLTTPVEISTPVTISAQA 253


>gi|19923559 EMSY protein [Homo sapiens]
          Length = 1322

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 113/474 (23%), Positives = 182/474 (38%), Gaps = 94/474 (19%)

Query: 11  LLPEEIMDTGITLVDDDSIEAVI---VSSPIPMETELEEIVNINSTGDSTATPISTEPIT 67
           L+P  +  T  T+  +    A I    S P+P ET  +E+V  + T  +T+TP ST    
Sbjct: 102 LMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTS-TTSTPTSTP--- 157

Query: 68  VYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLK 127
                            + S  TVK   P+      A   V + +   +  K    SD  
Sbjct: 158 ---------------VPSGSIATVKSPRPAS----PASNVVVLPSGSTVYVKSVSCSD-- 196

Query: 128 LGNQTLKPDGQKLILTTLGKSGSPIVLA-LPHSQLPQAQKVTTQAQSGDAKLPPQQIKVV 186
              +  KP  ++    T   S SP+VL  +P + +P ++ +T    SG  K+    ++ +
Sbjct: 197 ---EDEKPRKRR---RTNSSSSSPVVLKEVPKAVVPVSKTITVPV-SGSPKMS-NIMQSI 248

Query: 187 TIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLI 246
                P + PV  ++   P +Q  NTTTQ  ++ T    +  +        +   +TKL+
Sbjct: 249 ANSLPPHMSPV-KITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLV 307

Query: 247 FAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNK 306
                   +V   TTQ  P VI           T S++  +S S   GS+ ++ +  PN 
Sbjct: 308 ------PTSVIASTTQKPPVVI-----------TASQSSLVSNSSS-GSSSSTPSPIPNT 349

Query: 307 IAISPLKSPNKAVKSTVQTITVGGVSTSQFK---TIIP----LATAPNV-------QQIQ 352
           +A++ + S   +  S V +    GVSTS  K   T +P    L +AP         Q  Q
Sbjct: 350 VAVTAVVS---STPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQ 406

Query: 353 VPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPL--------------------QQAKP 392
            P  + + V+  T    +  + PVS        PL                    QQ +P
Sbjct: 407 SPKQQLYQVQQQTQQQVAQPS-PVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQP 465

Query: 393 VVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQI 446
             +   PV  ++P  S   +  V       T+++VTT    Q      T  P I
Sbjct: 466 SKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSI 519



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 96/444 (21%), Positives = 158/444 (35%), Gaps = 91/444 (20%)

Query: 23  LVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPI---STEPITVYSNHTNQVAVN 79
           LV    I +     P+ +      +V+ +S+G S++TP    +T  +T   + T  V V 
Sbjct: 306 LVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSV-VM 364

Query: 80  TTITKADSNTTVKPA---FPSGLQKLGAQTPVTI--------SANQIILNKVSQT----- 123
           +T+ +  S + +K A    PS    + A T +          S  Q +     QT     
Sbjct: 365 STVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVA 424

Query: 124 -----SDLKLGNQTLKPDGQKLILTTLGKSG---------------SPIVLALPHSQLPQ 163
                S  +   Q+  P G K  +    +SG                P+   LP S    
Sbjct: 425 QPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSP 484

Query: 164 AQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQ 223
              V++       KL            RP V P IG  A TPG+     TT  S++    
Sbjct: 485 IMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSII---- 540

Query: 224 LKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSK 283
                        T  P     +  K I+S  V+G TT+++   +  +            
Sbjct: 541 -------------TVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSK----------PN 577

Query: 284 TITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLA 343
            I + ++   G+T+      P K  ++ L   N   + T+QT+  G       K  I  A
Sbjct: 578 VIVVQKTTGKGTTIQG---LPGKNVVTTLL--NAGGEKTIQTVPTGA------KPAILTA 626

Query: 344 TAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAK-PVVVNTTPVRM 402
           T P  + I           +       S+ QP ++   T     QQ K  V++   PV  
Sbjct: 627 TRPITKMI-----------VTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTF 675

Query: 403 SVPIVSAQAVKQVVPKPINPTSQI 426
              +VS Q  +Q+V + +   S++
Sbjct: 676 QATVVSEQ-TRQLVTETLQQASRV 698



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 61/265 (23%), Positives = 102/265 (38%), Gaps = 49/265 (18%)

Query: 211 NTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAG 270
           ++++ P VL+      V ++K    P SG      I     NS           PP ++ 
Sbjct: 209 SSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSL----------PPHMSP 258

Query: 271 RVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPN-KAVKSTVQTITVG 329
             ++ + P T + T T ++  +I +T  S+T  PN ++    KS N  AV   V T  + 
Sbjct: 259 VKITFTKPSTQT-TNTTTQKVIIVTTSPSSTFVPNILS----KSHNYAAVTKLVPTSVIA 313

Query: 330 GVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             ST+Q   ++  A+  ++      GS             SSST     N    T  +  
Sbjct: 314 --STTQKPPVVITASQSSLVSNSSSGS-------------SSSTPSPIPNTVAVTAVVSS 358

Query: 390 AKPVVVNTTPVRMSVPIVSAQAVKQVVPKPI-----------------NPTSQIV-TTSQ 431
              VV++T    +S   +   + +   PK +                 +P  Q+     Q
Sbjct: 359 TPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQ 418

Query: 432 PQQRLIMPATPLPQIQPNLTNLPPG 456
            QQ++  P+    Q QP  + LPPG
Sbjct: 419 TQQQVAQPSPVSHQQQPQQSPLPPG 443


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 124/514 (24%), Positives = 173/514 (33%), Gaps = 68/514 (13%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 1898 TTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1956

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 1957 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPT 2006

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTP-----GSQL 209
                +Q P    +TT         P       T    P   P+   + +TP     G+Q 
Sbjct: 2007 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 2056

Query: 210  -----INTTT----QPSVLQTQQLKTVQIAKKPR-TPTSGPVITKLIFAKPINSKAVTGQ 259
                 I TTT     P+   TQ   T  I      TPT  P  T+     PI +      
Sbjct: 2057 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------ 2110

Query: 260  TTQVSP-PVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKA 318
            TT V+P P   G     +TP T + T+T + +   G+   +TT       ++P  +P   
Sbjct: 2111 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGT 2169

Query: 319  VKSTVQTITVGGVST-------SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSAS 370
               T   IT     T       +Q  T  P+ T   V     P G++      +T T+  
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2229

Query: 371  SSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTT 429
            + T   +   +  T P+     V    TP     P  +       V P P    +Q  TT
Sbjct: 2230 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289

Query: 430  SQPQQRLIMPATPLP--QIQPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQY 477
            +       +  TP P     P  T +   T + P P  TG              V P   
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349

Query: 478  VTQLQQSSYVSIASNSTFTGT---SGIQTQARLP 508
             T  Q  +   I + +T T T   +G QT    P
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 115/495 (23%), Positives = 168/495 (33%), Gaps = 53/495 (10%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 2082 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 2140

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 2141 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 2190

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 2191 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 2240

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 2241 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 2292

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 2293 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2349

Query: 332  ST-SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             T +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T P+  
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409

Query: 390  AKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP--QI 446
               V    TP     P  +       V P P    +Q  TT+       +  TP P    
Sbjct: 2410 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2469

Query: 447  QPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQYVTQLQQSSYVSIASNSTFT 496
             P  T +   T + P P  TG              V P    T  Q  +   I + +T T
Sbjct: 2470 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2529

Query: 497  GT---SGIQTQARLP 508
             T   +G QT    P
Sbjct: 2530 PTPTPTGTQTPTTTP 2544



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 115/495 (23%), Positives = 168/495 (33%), Gaps = 53/495 (10%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 2266 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 2324

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 2325 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 2374

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 2375 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 2424

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 2425 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 2476

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 2477 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2533

Query: 332  ST-SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             T +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T P+  
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593

Query: 390  AKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP--QI 446
               V    TP     P  +       V P P    +Q  TT+       +  TP P    
Sbjct: 2594 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2653

Query: 447  QPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQYVTQLQQSSYVSIASNSTFT 496
             P  T +   T + P P  TG              V P    T  Q  +   I + +T T
Sbjct: 2654 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2713

Query: 497  GT---SGIQTQARLP 508
             T   +G QT    P
Sbjct: 2714 PTPTPTGTQTPTTTP 2728



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 115/495 (23%), Positives = 168/495 (33%), Gaps = 53/495 (10%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 2450 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 2508

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 2509 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 2558

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 2559 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 2608

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 2609 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 2660

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 2661 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2717

Query: 332  ST-SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             T +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T P+  
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2777

Query: 390  AKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP--QI 446
               V    TP     P  +       V P P    +Q  TT+       +  TP P    
Sbjct: 2778 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2837

Query: 447  QPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQYVTQLQQSSYVSIASNSTFT 496
             P  T +   T + P P  TG              V P    T  Q  +   I + +T T
Sbjct: 2838 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2897

Query: 497  GT---SGIQTQARLP 508
             T   +G QT    P
Sbjct: 2898 PTPTPTGTQTPTTTP 2912



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 115/495 (23%), Positives = 168/495 (33%), Gaps = 53/495 (10%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 2634 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 2692

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 2693 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 2742

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 2743 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 2792

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 2793 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 2844

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 2845 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2901

Query: 332  ST-SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             T +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T P+  
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2961

Query: 390  AKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP--QI 446
               V    TP     P  +       V P P    +Q  TT+       +  TP P    
Sbjct: 2962 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3021

Query: 447  QPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQYVTQLQQSSYVSIASNSTFT 496
             P  T +   T + P P  TG              V P    T  Q  +   I + +T T
Sbjct: 3022 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3081

Query: 497  GT---SGIQTQARLP 508
             T   +G QT    P
Sbjct: 3082 PTPTPTGTQTPTTTP 3096



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 115/495 (23%), Positives = 168/495 (33%), Gaps = 53/495 (10%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 2818 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 2876

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 2877 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 2926

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 2927 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 2976

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 2977 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 3028

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 3029 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 3085

Query: 332  ST-SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             T +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T P+  
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3145

Query: 390  AKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP--QI 446
               V    TP     P  +       V P P    +Q  TT+       +  TP P    
Sbjct: 3146 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3205

Query: 447  QPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQYVTQLQQSSYVSIASNSTFT 496
             P  T +   T + P P  TG              V P    T  Q  +   I + +T T
Sbjct: 3206 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3265

Query: 497  GT---SGIQTQARLP 508
             T   +G QT    P
Sbjct: 3266 PTPTPTGTQTPTTTP 3280



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 115/495 (23%), Positives = 168/495 (33%), Gaps = 53/495 (10%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 3002 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 3060

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 3061 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 3110

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 3111 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 3160

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 3161 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 3212

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 3213 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 3269

Query: 332  ST-SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             T +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T P+  
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3329

Query: 390  AKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP--QI 446
               V    TP     P  +       V P P    +Q  TT+       +  TP P    
Sbjct: 3330 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3389

Query: 447  QPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQYVTQLQQSSYVSIASNSTFT 496
             P  T +   T + P P  TG              V P    T  Q  +   I + +T T
Sbjct: 3390 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3449

Query: 497  GT---SGIQTQARLP 508
             T   +G QT    P
Sbjct: 3450 PTPTPTGTQTPTTTP 3464



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 115/495 (23%), Positives = 168/495 (33%), Gaps = 53/495 (10%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 3186 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 3244

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 3245 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 3294

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 3295 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 3344

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 3345 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 3396

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 3397 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 3453

Query: 332  ST-SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             T +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T P+  
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513

Query: 390  AKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP--QI 446
               V    TP     P  +       V P P    +Q  TT+       +  TP P    
Sbjct: 3514 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3573

Query: 447  QPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQYVTQLQQSSYVSIASNSTFT 496
             P  T +   T + P P  TG              V P    T  Q  +   I + +T T
Sbjct: 3574 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3633

Query: 497  GT---SGIQTQARLP 508
             T   +G QT    P
Sbjct: 3634 PTPTPTGTQTPTTTP 3648



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 115/495 (23%), Positives = 168/495 (33%), Gaps = 53/495 (10%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 3370 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 3428

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 3429 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 3478

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 3479 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 3528

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 3529 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 3580

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 3581 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 3637

Query: 332  ST-SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             T +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T P+  
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3697

Query: 390  AKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP--QI 446
               V    TP     P  +       V P P    +Q  TT+       +  TP P    
Sbjct: 3698 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3757

Query: 447  QPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQYVTQLQQSSYVSIASNSTFT 496
             P  T +   T + P P  TG              V P    T  Q  +   I + +T T
Sbjct: 3758 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3817

Query: 497  GT---SGIQTQARLP 508
             T   +G QT    P
Sbjct: 3818 PTPTPTGTQTPTTTP 3832



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 115/495 (23%), Positives = 168/495 (33%), Gaps = 53/495 (10%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 3554 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 3612

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 3613 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 3662

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 3663 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 3712

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 3713 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 3764

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 3765 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 3821

Query: 332  ST-SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             T +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T P+  
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3881

Query: 390  AKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP--QI 446
               V    TP     P  +       V P P    +Q  TT+       +  TP P    
Sbjct: 3882 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3941

Query: 447  QPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQYVTQLQQSSYVSIASNSTFT 496
             P  T +   T + P P  TG              V P    T  Q  +   I + +T T
Sbjct: 3942 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4001

Query: 497  GT---SGIQTQARLP 508
             T   +G QT    P
Sbjct: 4002 PTPTPTGTQTPTTTP 4016



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 110/482 (22%), Positives = 161/482 (33%), Gaps = 50/482 (10%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 3738 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 3796

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 3797 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 3846

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 3847 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 3896

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 3897 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 3948

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 3949 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 4005

Query: 332  ST-SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ 389
             T +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T P+  
Sbjct: 4006 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4065

Query: 390  AKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPN 449
               V    TP     P  +       V     PT     T+ P   +    T  P   P 
Sbjct: 4066 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 4122

Query: 450  LTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGT---SGIQTQAR 506
             T  P  T +            V P    T  Q  +   I + +T T T   +G QT   
Sbjct: 4123 GTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4175

Query: 507  LP 508
             P
Sbjct: 4176 TP 4177



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 116/499 (23%), Positives = 164/499 (32%), Gaps = 63/499 (12%)

Query: 50   INSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVT 109
            + +T     TP +T PIT  +  T       T T   +  T            G QTP T
Sbjct: 1885 MTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1944

Query: 110  ISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTT 169
                 I        +    G QT        I TT   + +P       +Q P    +TT
Sbjct: 1945 ---TPITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTG---TQTPTTTPITT 1995

Query: 170  QAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTP-----GSQL-----INTTT----Q 215
                     P       T    P   P+   + +TP     G+Q      I TTT     
Sbjct: 1996 TTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2048

Query: 216  PSVLQTQQLKTVQIAKKPR-TPTSGPVITKLIFAKPINSKAVTGQTTQVSP-PVIAGRVL 273
            P+   TQ   T  I      TPT  P  T+     PI +      TT V+P P   G   
Sbjct: 2049 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTPTPTPTGTQT 2102

Query: 274  SQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVST 333
              +TP T + T+T + +   G+   +TT       ++P  +P      T   IT     T
Sbjct: 2103 PTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2161

Query: 334  -------SQFKTIIPLATAPNVQQIQVP-GSKFHYVRLVTATSASSSTQPVSQNPSTNTQ 385
                   +Q  T  P+ T   V     P G++      +T T+  + T   +   +  T 
Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2221

Query: 386  PLQQAKPVVVNTTPVRMSVPIVS-AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP 444
            P+     V    TP     P  +       V P P    +Q  TT+       +  TP P
Sbjct: 2222 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2281

Query: 445  --QIQPNLTNLPPGTVLAPAP-GTG---------NVGYAVLPAQYVTQLQQSSYVSIASN 492
                 P  T +   T + P P  TG              V P    T  Q  +   I + 
Sbjct: 2282 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2341

Query: 493  STFTGT---SGIQTQARLP 508
            +T T T   +G QT    P
Sbjct: 2342 TTVTPTPTPTGTQTPTTTP 2360



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 119/530 (22%), Positives = 186/530 (35%), Gaps = 75/530 (14%)

Query: 35   SSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPA 94
            ++PI   T +        T   T TPI+T   TV    T       T T   + TTV P 
Sbjct: 3899 TTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPT 3957

Query: 95   FPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             P+     G QTP T     I        +    G QT        I TT   + +P   
Sbjct: 3958 -PT---PTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPT 4007

Query: 155  ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                +Q P    +TT         P       T    P   P+   + +TP      T T
Sbjct: 4008 G---TQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT 4057

Query: 215  QPSVLQTQQLKTVQIAKKP---RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
             P+        TV     P   +TPT+ P+ T         +   TG  T  + P+    
Sbjct: 4058 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI---- 4109

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              + +T  TP+ T T +++        +TT TP     +  ++P     +T  T+T    
Sbjct: 4110 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 4166

Query: 332  ST-SQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQA 390
             T +Q  T  P+ T   V     P          T     +ST P+++  ++N  P + +
Sbjct: 4167 PTGTQTPTTTPITTTTTVTPTPTP------TGTQTGPPTHTSTAPIAELTTSNPPP-ESS 4219

Query: 391  KPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNL 450
             P    +T    S P+  +  +   +P    P  ++ +T+ P      P  P      + 
Sbjct: 4220 TPQTSRST----SSPLTESTTLLSTLP----PAIEMTSTAPPS----TPTAPTTTSGGHT 4267

Query: 451  TNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFN 510
             + PP T  +P PGT   G         T    SS  + ++  T T ++   T   L   
Sbjct: 4268 LSPPPSTTTSP-PGTPTRG---------TTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTP 4317

Query: 511  GIIPSESASRPRKPCNCTKSLCLKLYCDCFA------NGEFCNNCNCTNC 554
             II +       +P   +  +C  L    +A      NG + + C   NC
Sbjct: 4318 SIIRTTGL----RPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNC 4363



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 66/276 (23%), Positives = 88/276 (31%), Gaps = 22/276 (7%)

Query: 204  TPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITK-----LIFAKPINSKAVTG 258
            TP      TTT P         T  I     T T  P  T           P  +     
Sbjct: 1483 TPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542

Query: 259  QTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKA 318
             TT ++PP     +   +TP  P  T T        S   +TT +P  I  +        
Sbjct: 1543 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602

Query: 319  VKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQ 378
               T  T T    +T    T  P+   P      +P +        T T+   +T P   
Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPIT--PPTSTTTLPPTTTPSPPPTTTTTPPPTTTP--- 1657

Query: 379  NPSTNTQPLQQAKPVVVNTTPVRMSVP------IVSAQAVKQVVPKP-INPTSQIVTTSQ 431
            +P T T P   + P+   TTP   + P        S        P P   P+S I TT+ 
Sbjct: 1658 SPPTTTTP---SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT 1714

Query: 432  PQQRLI--MPATPLPQIQPNLTNLPPGTVLAPAPGT 465
            P        P T +    P  T  PP T +   P T
Sbjct: 1715 PSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPT 1750



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 96/407 (23%), Positives = 126/407 (30%), Gaps = 67/407 (16%)

Query: 35   SSPIPMETELEEIVNINSTGDST--ATPISTE----PITVYSNHTNQVAVNTTITKADSN 88
            ++P P  T    I    +   +T  + PIST     P T  S  T   +  TT     + 
Sbjct: 1430 TTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTT 1489

Query: 89   TTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKS 148
            TT  P  P+        TP+T  A+   L   +  S       T  P       TT   +
Sbjct: 1490 TTTTPP-PTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1548

Query: 149  GSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQ 208
                   LP +  P     TT         PP      T    P        +  TP   
Sbjct: 1549 PPTSTTTLPPTTTPSPPPTTTTTP------PP-----TTTPSPP--------TTTTPSPP 1589

Query: 209  LINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVI 268
             I TTT P         T      P T  S P  T +    P  S      TT  SPP  
Sbjct: 1590 TITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT---PPTSTTTLPPTTTPSPPPT 1646

Query: 269  AGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITV 328
                   +T  TPS   T + S  I     +TT TP      P  +P+  + +T      
Sbjct: 1647 TTTTPPPTT--TPSPPTTTTPSPPI-----TTTTTP-----PPTTTPSSPITTTPSP--- 1691

Query: 329  GGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQ 388
                        P  T         P S       +T T+  SST   S  P+T T P  
Sbjct: 1692 ------------PTTTMTTPSPTTTPSSP------ITTTTTPSSTTTPSPPPTTMTTPSP 1733

Query: 389  QAKPVVVNTT-----PVRMSVPIVSAQAVKQVVPKPINPTSQIVTTS 430
               P    TT     P   S P+ +      + P   +P S    T+
Sbjct: 1734 TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTT 1780



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 79/340 (23%), Positives = 108/340 (31%), Gaps = 47/340 (13%)

Query: 204  TPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQV 263
            TP     +TTT P    T    T      P T T  P IT      P  + +    TT  
Sbjct: 1405 TPSPPPTSTTTLPPTT-TPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTT 1463

Query: 264  SPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTV 323
             PP         +TP  P+ T +   +     T  +TT  P      P  +P     ST 
Sbjct: 1464 PPPT--------TTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST- 1514

Query: 324  QTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTN 383
                          T +P  T P+      P +        T T +  +T P++  P T+
Sbjct: 1515 --------------TTLPPTTTPS------PPTTTTTTPPPTTTPSPPTTTPIT--PPTS 1552

Query: 384  TQPL----QQAKPVVVNTTPVRMSVP------IVSAQAVKQVVPKPINPTS--QIVTTSQ 431
            T  L      + P    TTP   + P        S   +    P P    S     TT+ 
Sbjct: 1553 TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP 1612

Query: 432  PQQRLIMPATPLPQIQP-NLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIA 490
            P      P T  P   P + T LPP T  +P P T             T    S  ++  
Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT 1672

Query: 491  SN--STFTGTSGIQTQARLPFNGIIPSESASRPRKPCNCT 528
            +    T T +S I T    P   +      + P  P   T
Sbjct: 1673 TTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 67/267 (25%), Positives = 87/267 (32%), Gaps = 34/267 (12%)

Query: 204  TPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQV 263
            TP      TTT P         T  I     T T  P  T    + P  +      TT  
Sbjct: 1522 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP---SPPPTTTTTPPPTTTP 1578

Query: 264  SPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTV 323
            SPP          T  TP  T T S      +T   TT TP+    +P+  P        
Sbjct: 1579 SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT-TPSPPTTTPITPPTSTTTLPP 1637

Query: 324  QTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTN 383
             T      +T+   T  P  T P+      P        + T T+   +T P S  P T 
Sbjct: 1638 TTTPSPPPTTT---TTPPPTTTPSPPTTTTPSPP-----ITTTTTPPPTTTPSS--PITT 1687

Query: 384  TQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPL 443
            T     + P    TTP   + P             PI  T+   +T+ P        TP 
Sbjct: 1688 T----PSPPTTTMTTPSPTTTP-----------SSPITTTTTPSSTTTPSPPPTTMTTPS 1732

Query: 444  PQIQPN-----LTNLPPGTVLAPAPGT 465
            P   P+     +T LPP T  +P   T
Sbjct: 1733 PTTTPSPPTTTMTTLPPTTTSSPLTTT 1759



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 52/208 (25%), Positives = 71/208 (34%), Gaps = 31/208 (14%)

Query: 260  TTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAV 319
            TT   PP     +   +TP  P+ T T        S   +TT TP      P  +P+  +
Sbjct: 1404 TTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP-----PPTTTPSPPI 1458

Query: 320  KSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQN 379
             ST  T       +    T  P  T P+      P +        T T +  +T P++  
Sbjct: 1459 -STTTTPPPTTTPSPPTTTPSPPTTTPS------PPTTTTTTPPPTTTPSPPTTTPITPP 1511

Query: 380  PSTNTQP--LQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLI 437
             ST T P     + P    TTP   + P             PI P +   T         
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTP-------SPPTTTPITPPTSTTT--------- 1555

Query: 438  MPATPLPQIQPNLTNLPPGTVLAPAPGT 465
            +P T  P   P  T  PP T   P+P T
Sbjct: 1556 LPPTTTPSPPPTTTTTPPPTT-TPSPPT 1582



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 58/245 (23%), Positives = 78/245 (31%), Gaps = 14/245 (5%)

Query: 295  STLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVP 354
            +T +  T TP+    S    P     S   T T     T+     I   T P       P
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 355  GSKFHYVRLVTATSASSSTQP------VSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVS 408
                      T T +  +T P       S   +T T P     P    TTP+  + P  +
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI--TPPAST 1514

Query: 409  AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQP-NLTNLPPGTVLAPAPGTGN 467
                    P P  PT+   TT+ P      P T  P   P + T LPP T  +P P T  
Sbjct: 1515 TTLPPTTTPSP--PTT--TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1570

Query: 468  V-GYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCN 526
                   P+   T       ++  +    T  S   T    P     PS   + P  P  
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT 1630

Query: 527  CTKSL 531
             T +L
Sbjct: 1631 STTTL 1635


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 118/546 (21%), Positives = 192/546 (35%), Gaps = 81/546 (14%)

Query: 5    PAEVNSLLPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTE 64
            P  V SL      DT    V D S  +   ++P+P+ T L  +    STGD+T   + T+
Sbjct: 3408 PLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPV-TSLSSV----STGDTTPLLV-TD 3461

Query: 65   PITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPV------TISANQIILN 118
              +V + H   + V  T + +  +TT  P   +     G  TP+      ++S       
Sbjct: 3462 ASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPL 3521

Query: 119  KVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKL 178
             V+  S +  G+ T  P      +T    + +     LP +        T+ A +G A  
Sbjct: 3522 LVTDASSVSTGHATPLP------VTDTSSASTGDTTRLPVTD-------TSSASTGQATP 3568

Query: 179  PPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTS 238
             P  I   +  G     PV   S+++ G       T PS   T  +  + +       T 
Sbjct: 3569 LPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTG 3628

Query: 239  GPVITKLIFAKPIN------------SKAVTGQTTQV------------SPPVIAGRVLS 274
                  +  A  ++            S A TG TT +            + P+    + S
Sbjct: 3629 HATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSS 3688

Query: 275  QSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAIS-----PLKSPNKAVKSTVQTITVG 329
             ST  T    +T + S   G         P+ ++       P+ SP+ A       + V 
Sbjct: 3689 VSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVT 3748

Query: 330  GVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQ- 388
            G+S++      PL             S  H   L    ++S+ST   ++ P T+      
Sbjct: 3749 GLSSASTGDTTPLPVTDTSS-----ASTRHATPLPVTDTSSASTDDTTRLPVTDVSSAST 3803

Query: 389  -QAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVT---TSQP----QQRLIMPA 440
              A P+ V +T         S+ +     P P+  TS + T   TS P           A
Sbjct: 3804 GHATPLPVTST---------SSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHA 3854

Query: 441  TPLPQIQPNLTNLPPGTVLAPAPGTGNV--GYAV-LPAQYVTQLQQSSYVSIASNSTFTG 497
            TPLP    +  +    T L P   T +V  G+A  LP    +         +   ST + 
Sbjct: 3855 TPLPVTDTSSVSTGHATPL-PVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSA 3913

Query: 498  TSGIQT 503
            ++G  T
Sbjct: 3914 STGDTT 3919



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 106/489 (21%), Positives = 182/489 (37%), Gaps = 68/489 (13%)

Query: 52   STGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTIS 111
            STGD+T  P+ T P +  + HT  + V    + +  +T+  P   +     G  TP+   
Sbjct: 3338 STGDTTPLPV-TSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPL--- 3393

Query: 112  ANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQA 171
                    V+ TS +  G+ T  P      +T+L    +     LP +    A   T QA
Sbjct: 3394 -------PVTDTSSVSTGHATPLP------VTSLSSVSTGDTTPLPVTDASSAS--TGQA 3438

Query: 172  QSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAK 231
                  LP   +  V+ G   +  P++   A    S      T   V  T    T    +
Sbjct: 3439 ----TPLPVTSLSSVSTG---DTTPLLVTDA---SSVSTGHATPLPVTDTSSASTGDTTR 3488

Query: 232  KPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESG 291
             P T TS     +   A P+   +++  +T  + P++     S ST       +T + S 
Sbjct: 3489 LPVTDTSSASTGQ---ATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSA 3545

Query: 292  VIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQI 351
              G T         ++ ++   S +   ++T   +T+   S+S   T +P+ +  +V   
Sbjct: 3546 STGDT--------TRLPVTDTSSASTG-QATPLPVTIPSSSSSGHTTPLPVTSTSSV--- 3593

Query: 352  QVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQ--QAKPVVVN-----TTPVRMSV 404
                S  H   L   + +S+ST  V+  P T+T       A P++V      +T     +
Sbjct: 3594 ----STGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPL 3649

Query: 405  PIVSAQAVK--QVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPA 462
            P+  A +       P P+  TS   T     Q   +P T L  +    T   P T  + A
Sbjct: 3650 PVTDASSASTGDTTPLPVTDTSSAST----GQATPLPVTSLSSVSTGDTTPLPVTDASSA 3705

Query: 463  PGTGNVGYAV-LPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRP 521
                + G+A  LP    + +     + +   S  + ++G  T   LP  G+  + +    
Sbjct: 3706 ----STGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATP--LPVTGLSSASTGDTT 3759

Query: 522  RKPCNCTKS 530
              P   T S
Sbjct: 3760 PLPVTDTSS 3768



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 108/474 (22%), Positives = 170/474 (35%), Gaps = 79/474 (16%)

Query: 5    PAEVNSLLPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTE 64
            P  V SL      DT    V   S  +   ++P+P+ T+   +    STG +T  P+ T 
Sbjct: 1520 PLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPV-TDASSV----STGHTTPLPV-TS 1573

Query: 65   PITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTS 124
            P +  + HT  + V  T + +  +TT  P         G  TP+           V+ TS
Sbjct: 1574 PSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPL----------PVTDTS 1623

Query: 125  DLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHS-----QLPQAQKVTTQAQSGDA-KL 178
                G+ T  P      L+T     +P+ +  P S       P     T+ A +G A  L
Sbjct: 1624 SASTGDTTPLPVTNASSLST--GHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPL 1681

Query: 179  PPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTS 238
            P   +   T      + PV  VS+ + G        Q + L    L +V        P +
Sbjct: 1682 PVTGLSSATTDDTTRL-PVTDVSSASTG--------QATPLPVTSLSSVSTGDTTPLPVT 1732

Query: 239  GPVITKLIFAKPI----NSKAVTGQTTQV------------SPPVIAGRVLSQSTPGTPS 282
             P       A P+     S A TGQ T +            + P+    + S ST  T  
Sbjct: 1733 SPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTR 1792

Query: 283  KTITISESGVIGSTLNSTTQTPNKIA---ISPLKSPNKAVKSTVQT----ITVGGVSTSQ 335
              +T   S   G  +     +P+  +    +PL   + +  ST  T    +T+   ++S 
Sbjct: 1793 LPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSG 1852

Query: 336  FKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVV 395
              T +P+  A +V       S  H   L+   ++S ST   +  P T+T           
Sbjct: 1853 HTTSLPVTDASSV-------STGHATSLLVTDASSVSTGDTTPLPVTDTNSASTG----- 1900

Query: 396  NTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPN 449
            +TTP  + V   S+ +       P+   S   T            TPLP   P+
Sbjct: 1901 DTTP--LHVTDASSVSTGHATSLPVTSLSSASTGD---------TTPLPVTSPS 1943



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 109/496 (21%), Positives = 177/496 (35%), Gaps = 61/496 (12%)

Query: 24   VDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTIT 83
            V D S  +   ++P+P+ T L  +    STGD+T  P+ T P +  + HT  + V  T +
Sbjct: 2947 VTDTSSASTGHATPLPV-TSLSSV----STGDTTPLPV-TSPSSASTGHTTPLPVTDTSS 3000

Query: 84   KADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILT 143
             +    T  P   +     G  TP+           V+ TS    G  T  P      ++
Sbjct: 3001 ASTGQATALPVTSTSSASTGDTTPL----------PVTDTSSASTGQATPLPVTSLSSVS 3050

Query: 144  TLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSAL 203
            T   +  P+      S       + T A S                G+    PV  +S++
Sbjct: 3051 TGDTTPLPVTSPSSASTGHATPLLVTDASSAST-------------GQATPLPVTSLSSV 3097

Query: 204  TPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPI--NSKAVTGQTT 261
            + G       T PS   T    ++     P T TS    T    + P+   S A TG TT
Sbjct: 3098 STGDTTPLPVTSPSSASTGHATSL-----PVTDTSS-ASTGDTTSLPVTDTSSAYTGDTT 3151

Query: 262  QVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKS 321
             +     +      +TP   ++T ++S +G     L +   + +    +PL   + +  S
Sbjct: 3152 SLPVTDTSSSSTGDTTPLLVTETSSVS-TGHATPLLVTDASSASTGHATPLHVTSPSSAS 3210

Query: 322  TVQTITVGGVSTSQFKT--IIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQN 379
            T  T  V    TS   T    PL             ++     + +A++  ++  PV+  
Sbjct: 3211 TGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNT 3270

Query: 380  PST---NTQPLQQAKPVVVNT---TPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQ 433
             S    +T PL    P   +T   TP  + V   S+ +     P P+  TS   T     
Sbjct: 3271 SSVSTGDTMPLPVTSPSSASTGHATP--LPVTSTSSASTGHATPVPVTSTSSASTGH--- 3325

Query: 434  QRLIMPATPLPQIQPNLTNLPPGTVL-APAPGTGNVGYAVLPAQYVTQLQQSSYVSIASN 492
                   TPLP    +  +    T L   +P + + G+      +VT +  S+     S 
Sbjct: 3326 ------TTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTT--PLHVT-IPSSASTGDTST 3376

Query: 493  STFTGTSGIQTQARLP 508
               TG S   T    P
Sbjct: 3377 LPVTGASSASTGHATP 3392



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 127/531 (23%), Positives = 199/531 (37%), Gaps = 86/531 (16%)

Query: 19  TGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTAT--PISTEPITVYS-NHTNQ 75
           TG TL +     +V V+  + M      +V  +  G S AT    ST+  T +S NH  Q
Sbjct: 270 TGSTLGNPGETSSVPVTGSL-MPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQ 328

Query: 76  VAVNTTITKADSNTTVKP-------AFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKL 128
               T +++ ++  T+ P       + PSG    G  +  T  + +   +  S  S+  L
Sbjct: 329 SVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFL 388

Query: 129 GNQTL--KPDGQKLIL-----TTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPP- 180
               +   P  +   L     T+L  SG+   +    S +  +  ++T      + LPP 
Sbjct: 389 VTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTAL--SPSSLPPK 446

Query: 181 -------QQIKVVTIGGRPEVKPVIGVSALTPGSQ-----LINTTTQPSVLQTQQLKTVQ 228
                  QQ +     GRP  +     S+ +PG       L  TTT PS   ++   T  
Sbjct: 447 ISTAFHTQQSEGAETTGRPHER-----SSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWS 501

Query: 229 IAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTP----SKT 284
             + P T T     T+L+   P    A T        P +  +V +   PG P    S +
Sbjct: 502 QTELPSTSTG--AATRLVTGNPSTGTAGT-------IPRVPSKVSAIGEPGEPTTYSSHS 552

Query: 285 ITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLAT 344
            T+ ++   G+    T +T      + L SP+ +V   ++T T    S        P+  
Sbjct: 553 TTLPKTTGAGAQTQWTQET-GTTGEALLSSPSYSVTQMIKTATSPSSS--------PMLD 603

Query: 345 APNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPST----NTQPLQQAKPVVVNTTPV 400
               QQI    S  H     T+TS   S   VSQ   T     TQ  Q  + V   T   
Sbjct: 604 RHTSQQITTAPSTNHSTIHSTSTSPQES-PAVSQRGHTQAPQTTQESQTTRSVSPMTDTK 662

Query: 401 RMSVP----IVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPG 456
            ++ P      S  +  ++VP+   PT    TT            P P    + T  P  
Sbjct: 663 TVTTPGSSFTASGHSPSEIVPQDA-PTISAATT----------FAPAPTGDGHTTQAPT- 710

Query: 457 TVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASN--STFTGTSGIQTQA 505
           T L  AP + +   A L     T L ++  +++A++  ST  G  G  T A
Sbjct: 711 TALQAAPSSHD---ATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSA 758



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 110/495 (22%), Positives = 178/495 (35%), Gaps = 54/495 (10%)

Query: 52   STGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTI- 110
            STG +T  P+ T P +V + HT  + V  T +++  + T  P         G  TP+ + 
Sbjct: 1002 STGHATPLPV-TSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVT 1060

Query: 111  -----SANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIV----LALPHSQL 161
                 S   +    V+  S    G+ T  P       +T   +  P+     ++  H+  
Sbjct: 1061 DTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHT-T 1119

Query: 162  PQAQKVTTQAQSGDA-KLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQ 220
            P     T+ A +G A  LP      V+ G    +      SA         +T Q + L 
Sbjct: 1120 PLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSA---------STGQATPLP 1170

Query: 221  TQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGT 280
               L +V        P + P       A P+     +  +T  + P+      S ST   
Sbjct: 1171 VTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHA 1230

Query: 281  PSKTITISESGVIGST----LNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQF 336
             S  +TI  +   G T    +  T+      A S L +   +V ST  T  +   STS  
Sbjct: 1231 TSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSV-STGDTTPLPVTSTSSA 1289

Query: 337  KT--IIPL-ATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPV 393
             T  + PL  T+P+        S  H   L   + +S+ST      P T+          
Sbjct: 1290 STGHVTPLHVTSPS------SASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTG--- 1340

Query: 394  VVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNL 453
              +TTP    +P+  A +V      P++ T    +++   Q   +P T L  +    T  
Sbjct: 1341 --DTTP----LPVTDASSVSTGHTTPLHVTD--ASSASTGQATPLPVTSLSSVSTGDTTP 1392

Query: 454  PPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGII 513
             P T    +P + + G+A      VT    +S    A+    T  S + T         I
Sbjct: 1393 LPVT----SPSSASTGHAT--PLLVTDTSSAS-TGHATPLPVTDASSVSTDHATSLPVTI 1445

Query: 514  PSESASRPRKPCNCT 528
            PS +++    P   T
Sbjct: 1446 PSAASTGHTTPLPVT 1460



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 96/448 (21%), Positives = 165/448 (36%), Gaps = 55/448 (12%)

Query: 52   STGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPV--- 108
            STGD+T  P+ T P +  S HT  + V    +    + T  P   +     G  TP+   
Sbjct: 1930 STGDTTPLPV-TSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVT 1988

Query: 109  ---TISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQ 165
               ++S        V+ TS +  G  T  P      +T+L  + +     LP +      
Sbjct: 1989 DASSVSTGHATPLPVTDTSSVSTGQATPLP------VTSLSSASTGDTTPLPVTD----- 2037

Query: 166  KVTTQAQSG-DAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQL 224
              T+ A +G D  LP   +  V+ G    + PV   S+ + G       T  S + T   
Sbjct: 2038 --TSSASTGQDTPLPVTSLSSVSTGDTTPL-PVTSPSSASTGHATPLLVTDASSVSTGHA 2094

Query: 225  KTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTT--QVSPPVIAGRVLSQSTPGTPS 282
             ++ +       T       +  A  ++    TG TT   V+ P  A    +   P T +
Sbjct: 2095 TSLLVTDASSVSTGHATALHVTDASSLS----TGDTTPLPVTSPSSASTGDTTPLPVTDT 2150

Query: 283  KTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPL 342
             +++   +  +  T  S+  T +  ++ P+   + A       + V   S++      PL
Sbjct: 2151 SSVSTGHATSLPVTDTSSASTGHATSL-PVTDTSSASTGHATPLPVTDTSSASTGQATPL 2209

Query: 343  -ATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPST--------NTQPLQQAKPV 393
              T+P+        S  H + L+   ++S+ST   +  P T        +T PL      
Sbjct: 2210 PVTSPS------SASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDAS 2263

Query: 394  VVNTTPVRMSVPIVSAQAVK--QVVPKPINPTSQIVT-------TSQPQQRLIMPATPLP 444
             V+T     S+P+ S  +V      P P+   S   T        +         ATPLP
Sbjct: 2264 SVSTGHA-TSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLP 2322

Query: 445  QIQPNLTNLPPGTVL-APAPGTGNVGYA 471
                +  +    T L   +P + + G+A
Sbjct: 2323 VTSLSSASTGDTTPLPVTSPSSASTGHA 2350



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 100/491 (20%), Positives = 173/491 (35%), Gaps = 66/491 (13%)

Query: 24   VDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTIT 83
            V D S  +   ++P+P+ +     ++  STGD+T  P+ T P +  + H   + V    +
Sbjct: 2307 VTDASSASTGHATPLPVTS-----LSSASTGDTTPLPV-TSPSSASTGHATPLHVTDASS 2360

Query: 84   KADSNTTVKPAFPSGLQKLGAQTPVTI------SANQIILNKVSQTSDLKLGNQTLKP-- 135
             +  +TT  P   S     G  TP+ +      S        V+ TS    G+ T  P  
Sbjct: 2361 VSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVT 2420

Query: 136  --------DGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGD-AKLPPQQIKVV 186
                    D  +L +T +  + +     LP +        T+ A +GD   LP      V
Sbjct: 2421 GLSSASTGDTTRLPVTNVSSASTGHATPLPVTS-------TSSASTGDTTPLPGTDTSSV 2473

Query: 187  TIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLI 246
            + G    +  V   S+++ G       T PS   T     + +   P   T       + 
Sbjct: 2474 STGHTTPLL-VTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVT 2532

Query: 247  FAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNK 306
             A  ++++  T  +  V+ P  A    + S P T +   +   +  +  T  S+  T + 
Sbjct: 2533 NASSLSTRHAT--SLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGD- 2589

Query: 307  IAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTA 366
               +PL   +    ST Q   +    TS   T     T P                L   
Sbjct: 2590 --TTPLPVTDTYSASTGQATPLPVTDTSSAST---GDTTP----------------LPVT 2628

Query: 367  TSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQI 426
             ++S+ST   +  P TNT  +        + TP+ ++ P  S+ +     P P+   S +
Sbjct: 2629 DTSSASTGHATPLPVTNTSSVSTG-----HATPLHVTSP--SSASTGHTTPLPVTDASSV 2681

Query: 427  VTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSY 486
             T         +P T    +        P T+ + A         V  A  V+    +S 
Sbjct: 2682 STGHATS----LPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSL 2737

Query: 487  VSIASNSTFTG 497
                ++S  TG
Sbjct: 2738 PVTDASSVSTG 2748



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 104/496 (20%), Positives = 175/496 (35%), Gaps = 68/496 (13%)

Query: 53   TGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISA 112
            TG +T+ P+ T P +  S HT  + V    + +  + T  P   +     G  TP+    
Sbjct: 2699 TGHATSLPV-TIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPL---- 2753

Query: 113  NQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQ 172
                   V+  S +  G+ T  P      LT+L    +     LP +        T+ A 
Sbjct: 2754 ------PVTDASSVSTGHATPLP------LTSLSSVSTGDTTPLPVTD-------TSSAS 2794

Query: 173  SGDA-KLPPQQIKVVTIGGRPEVKPVIGVSALTPG---SQLINTTTQPSV--------LQ 220
            +G A  LP   +  V+ G    + PV   S+ + G   S  +  T+  S           
Sbjct: 2795 TGQATPLPVTSLSSVSTGDTTPL-PVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTD 2853

Query: 221  TQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAV-TGQTT--QVSPPVIAGRVLSQST 277
            T    T      P T TS   I         ++ ++ TG  T   V+ P  A    +   
Sbjct: 2854 TSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPL 2913

Query: 278  PGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFK 337
            P T + + +   +  +  T  S+  T +   + P+   + A       + V  +S+    
Sbjct: 2914 PVTDTSSASTGHANPLHVTSPSSASTGHATPL-PVTDTSSASTGHATPLPVTSLSSVSTG 2972

Query: 338  TIIPL-ATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVN 396
               PL  T+P+        S  H   L    ++S+ST   +  P T+T           +
Sbjct: 2973 DTTPLPVTSPS------SASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTG-----D 3021

Query: 397  TTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPG 456
            TTP  + V   S+ +  Q  P P+   S + T            TPLP   P+  +    
Sbjct: 3022 TTP--LPVTDTSSASTGQATPLPVTSLSSVSTGD---------TTPLPVTSPSSASTGHA 3070

Query: 457  T-VLAPAPGTGNVGYAV-LPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIP 514
            T +L     + + G A  LP   ++ +       +   S  + ++G  T   LP      
Sbjct: 3071 TPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATS--LPVTDTSS 3128

Query: 515  SESASRPRKPCNCTKS 530
            + +      P   T S
Sbjct: 3129 ASTGDTTSLPVTDTSS 3144



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 110/524 (20%), Positives = 188/524 (35%), Gaps = 59/524 (11%)

Query: 23   LVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTI 82
            LV D S  +   ++P+P+        N  STGD+T   + T+  +V + H   + V +  
Sbjct: 1874 LVTDASSVSTGDTTPLPVTD-----TNSASTGDTTPLHV-TDASSVSTGHATSLPVTSLS 1927

Query: 83   TKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLIL 142
            + +  +TT  P         G  TP+           V+  S +  G+ T  P      +
Sbjct: 1928 SASTGDTTPLPVTSPSSASSGHTTPL----------PVTDASSVPTGHATSLPVTDASSV 1977

Query: 143  TTLGKSGSPIVLALPHS---QLPQAQKVTTQAQSGDA-KLPPQQIKVVTIGGRPEVKPVI 198
            +T   +  P+  A   S     P     T+   +G A  LP   +   + G    + PV 
Sbjct: 1978 STGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPL-PVT 2036

Query: 199  GVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTG 258
              S+ + G        Q + L    L +V        P + P       A P+     + 
Sbjct: 2037 DTSSASTG--------QDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASS 2088

Query: 259  QTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIA---ISPLKSP 315
             +T  +  ++     S ST    +  +T + S   G T      +P+  +    +PL   
Sbjct: 2089 VSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVT 2148

Query: 316  NKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQ- 374
            + +  ST    ++    TS   T    AT+  V       +       VT TS++S+ Q 
Sbjct: 2149 DTSSVSTGHATSLPVTDTSSAST--GHATSLPVTDTSSASTGHATPLPVTDTSSASTGQA 2206

Query: 375  ---PVSQNPSTNTQPLQQAKPVVVNTT-------PVRMSVPIVSAQAVKQVVPKPINPTS 424
               PV+   S +T     A P++V  T          + V  +S+ +     P P+   S
Sbjct: 2207 TPLPVTSPSSAST---GHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDAS 2263

Query: 425  QIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQS 484
             + T         +P T L  +    T   P T    +P + + G+A     +VT    +
Sbjct: 2264 SVSTGHATS----LPVTSLSSVSTGDTTPLPVT----SPSSASTGHAT--PLHVTDASSA 2313

Query: 485  SYVSIASNSTFTGTSGIQTQARLPFNGIIPSESASRPRKPCNCT 528
            S    A+    T  S   T    P     PS +++    P + T
Sbjct: 2314 S-TGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVT 2356



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 71/338 (21%), Positives = 125/338 (36%), Gaps = 32/338 (9%)

Query: 24   VDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTIT 83
            V D S  +   ++P+P+ +      +  STG +T  P+ T P +  + H   V V +T +
Sbjct: 3859 VTDTSSVSTGHATPLPVTS-----TSSVSTGHATPLPV-TSPSSASTGHATPVPVTSTSS 3912

Query: 84   KADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILT 143
             +  +TT  P   +     G  TP+ +++        + T  +   +         L LT
Sbjct: 3913 ASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLT 3972

Query: 144  TLGKSGSPIVLALPHSQLPQAQ-------KVT--TQAQSGDAKLPPQQIKVVTIGGRPEV 194
            +L    +     LP +    A         VT  +   +GD    P  I      G    
Sbjct: 3973 SLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTS 4032

Query: 195  KPVIGVSALTPG-----------SQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVIT 243
             PV   S+++ G           S     TT   V  T    T      P T TS     
Sbjct: 4033 LPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSS---A 4089

Query: 244  KLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQT 303
                A P+   +++  +T  + P+      S ST  + S  + +   G+  +T +  T  
Sbjct: 4090 STGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDS-PLKMETPGM--TTPSLKTDG 4146

Query: 304  PNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIP 341
              + A SP  + ++ + ST+ +  +   ST+    I+P
Sbjct: 4147 GRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPIPILP 4184



 Score = 30.8 bits (68), Expect = 4.8
 Identities = 72/350 (20%), Positives = 119/350 (34%), Gaps = 68/350 (19%)

Query: 49  NINSTGDSTATP---ISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQ 105
           N+  T     +P    +T  +   +N +   +   T+T +  +T   P   S +   G+ 
Sbjct: 230 NVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSL 289

Query: 106 TPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQ 165
            PVT +A                   T  P+GQ           SP   +   +Q   A 
Sbjct: 290 MPVTSAA-----------------LVTFDPEGQ-----------SPATFSRTSTQDTTAF 321

Query: 166 KVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTT---QPSVLQTQ 222
               Q QS +                  V  +  ++ LTP    + T+T    PS     
Sbjct: 322 SKNHQTQSVET---------------TRVSQINTLNTLTP----VTTSTVLSSPSGFNPS 362

Query: 223 QLKTVQIAKKPRTPTSGP-------VITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQ 275
              + +      T TS P       ++T  +F  P +  +  G T + S  V      S 
Sbjct: 363 GTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSV------SG 416

Query: 276 STPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQ 335
           +     SK  TI  S  + ST  S +  P KI+ +     ++  ++T +       S   
Sbjct: 417 TISAITSKVSTIWWSDTL-STALSPSSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGV 475

Query: 336 FKTIIPL-ATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNT 384
            + I  L  T          G        + +TS  ++T+ V+ NPST T
Sbjct: 476 SQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGT 525


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 103/489 (21%), Positives = 172/489 (35%), Gaps = 46/489 (9%)

Query: 42   TELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQK 101
            TE      +     STAT  ST+  T  + H +  A   T+T + +  +  P   + L  
Sbjct: 4454 TEPSTTATVTVPTGSTATASSTQA-TAGTPHVSTTATTPTVTSSKATPSSSPGTATALPA 4512

Query: 102  LG--AQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHS 159
            L   A TP   S   I  + +  T      +QT  P      ++T   S +P  +   H+
Sbjct: 4513 LRSTATTPTATSFTAIPSSSLGTTWTRL--SQTTTPTAT---MSTATPSSTPETV---HT 4564

Query: 160  QLPQAQKVTTQAQSGDAKLPPQ--------QIKVVTIGGRPEVKPVIGVSALTPGSQLIN 211
                    TT   +G    P          ++   T  G          +ALTP   +  
Sbjct: 4565 STVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIST 4624

Query: 212  TTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVS--PPVIA 269
            TTT  +   T    TV  +  P T  +  V+T         S A    +TQ S  PP + 
Sbjct: 4625 TTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLT 4684

Query: 270  GRVLS----------QSTPGTPSKTITISESGVIGSTLNS---TTQTPNKIAISPLKSPN 316
                +           STPGT   T  ++ +    +  +S   ++ +P      P+ + +
Sbjct: 4685 TTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLT-S 4743

Query: 317  KAVKST------VQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSAS 370
             A KST      + + T+    T   +T  P++T   +     P +      L T  + +
Sbjct: 4744 TATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMT 4803

Query: 371  SSTQPVSQNPST--NTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPIN-PTSQIV 427
             +T   +   ST   T+ L +       T     +  + S      ++ +P    T  + 
Sbjct: 4804 RATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVP 4863

Query: 428  TTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYV 487
            T S       +     P++   +  +P  T  +  P +  VG    PA   + L   S V
Sbjct: 4864 TGSTATASSTLGTAHTPKVVTTMATMPTATA-STVPSSSTVGTTRTPAVLPSSLPTFS-V 4921

Query: 488  SIASNSTFT 496
            S  S+S  T
Sbjct: 4922 STVSSSVLT 4930



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 98/444 (22%), Positives = 152/444 (34%), Gaps = 65/444 (14%)

Query: 42   TELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQK 101
            TEL        +  STATP ST                TT    + +TT     P+G   
Sbjct: 2440 TELTTTATTTESTGSTATPSSTP--------------GTTWILTEPSTTATVTVPTGSTA 2485

Query: 102  LGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQL 161
              + T  T     +     + T           P G    L  L +S +    A   + +
Sbjct: 2486 TASSTQATAGTPHVSTTATTPTVTSSKATPFSSP-GTATALPAL-RSTATTPTATSFTAI 2543

Query: 162  PQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPE---VKPVIGVSALTPGS--QLINTTTQP 216
            P +   TT  +      P   +   T    PE      V+  +A T G+   +   ++ P
Sbjct: 2544 PSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTP 2603

Query: 217  SVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQ---VSPPVIAGRV- 272
                T ++ T        TP+S P   + +   P+     T  TT+   V+P  I G   
Sbjct: 2604 GTAHTTKVLTTTTTGFTATPSSSPGTARTL---PVWISTTTTPTTRGSTVTPSSIPGTTH 2660

Query: 273  ---------------------LSQSTPGT-PSKTITISESGVIGSTLNSTTQTPNKIAIS 310
                                  S  T GT PS T T +     GST N ++ TP    I 
Sbjct: 2661 TPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSS-TPGTTPIP 2719

Query: 311  P-LKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRL--VTAT 367
            P L +      +T  T+T      +     +P  TA    +   P S  H VR    +AT
Sbjct: 2720 PVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSP-HTVRTAWTSAT 2778

Query: 368  SASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQ------VVPKPIN 421
            S +  T  +++ PST T     A       +   +S P  S++  +         P    
Sbjct: 2779 SGTLGTTHITE-PSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTR 2837

Query: 422  PTSQIVTTSQPQQ---RLIMPATP 442
             TS+   T+ P +     ++P++P
Sbjct: 2838 ATSRTTATATPSKTRTSTLLPSSP 2861



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 98/413 (23%), Positives = 148/413 (35%), Gaps = 52/413 (12%)

Query: 52   STGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLG--AQTPVT 109
            STG STATP ST             A   T+T + +  +  P   + L  L   A TP  
Sbjct: 1922 STG-STATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTA 1980

Query: 110  ISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTT 169
             S   I  + +  T      +QT  P      ++T   S +P      H+        TT
Sbjct: 1981 TSVTPIPSSSLGTTWTRL--SQTTTPTAT---MSTATPSSTP---ETAHTSTVLTATATT 2032

Query: 170  QAQSGDAKLPPQ--------QIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQT 221
               +G    P          ++   T  G          +ALTP    I+TTT P    T
Sbjct: 2033 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP-PVWISTTTTP----T 2087

Query: 222  QQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTP 281
             +  TV  +  P T  +  V+T         S A    +TQ S            TP  P
Sbjct: 2088 TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTS-----------GTP--P 2134

Query: 282  SKTITISESGVIGSTLNSTTQTPNKIAISP-LKSPNKAVKSTVQTITVGGVSTSQFKTII 340
            S T T +     GST N ++ TP    I P L +      +T  T+T      +     +
Sbjct: 2135 SLTTTATTITATGSTTNPSS-TPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPV 2193

Query: 341  PLATAPNVQQIQVPGSKFHYVRL--VTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTT 398
            P  T        +P S  H VR    +ATS    T  +++  +  +  L        ++T
Sbjct: 2194 P-NTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHST 2252

Query: 399  PVRMSVPIVSAQAVKQ------VVPKPINPTSQIVTTSQPQQ---RLIMPATP 442
            P  +S P  S++  +         P     TS+   T+ P +     ++P++P
Sbjct: 2253 PA-LSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSP 2304



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 110/505 (21%), Positives = 177/505 (35%), Gaps = 55/505 (10%)

Query: 13   PEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNH 72
            P +++ +  T     S +A   SSP    T     V  ++   STAT ++  PI   +  
Sbjct: 4281 PPKVLTSPATTPTATSSKATSSSSP---RTATTLPVLTSTATKSTATSVT--PIPSSTLG 4335

Query: 73   TNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQT 132
            T       T T   + +T+ P+           TP T   + ++  K + T      +  
Sbjct: 4336 TTGTLPEQTTTPVATMSTIHPS----------STPETTHTSTVLTTKATTTRATSSTSTP 4385

Query: 133  LKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRP 192
                G   ILT L  + +      P +  P +   TT   +          ++ T     
Sbjct: 4386 SSTPGTTWILTELTTAATTTAATGP-TATPSSTPGTTWILT----------ELTTTATTT 4434

Query: 193  EVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSG--PVITKLIFAKP 250
                     + TPG+  I   T+PS   T  + T   A    T  +   P ++       
Sbjct: 4435 ASTGSTATPSSTPGTTWI--LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT 4492

Query: 251  INSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKT-ITISESGVIGSTLNSTTQTPNKIAI 309
            + S   T  +   SP         +ST  TP+ T  T   S  +G+T    +QT    A 
Sbjct: 4493 VTSSKATPSS---SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTAT 4549

Query: 310  SPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSA 369
                +P+    ST +T+    V T+   T    AT         PG+  H  ++ T T+ 
Sbjct: 4550 MSTATPS----STPETVHTSTVLTATATT--TGATGSVATPSSTPGTA-HTTKVPTTTTT 4602

Query: 370  SSSTQPVSQNPSTNTQPLQQAKPVVVNTTPV-RMSVPIVSAQAVKQVVPKPINPTSQIVT 428
              +  P S +P T   P     PV ++TT     + P  S   V          T++++T
Sbjct: 4603 GFTATP-SSSPGTALTP-----PVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLT 4656

Query: 429  TSQPQQRLIMPATPLPQIQ-----PNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQ 483
            T+         ATP    Q     P+LT     T +     T N             L  
Sbjct: 4657 TTTTTVATGSMATPSSSTQTSGTPPSLTT--TATTITATGSTTNPSSTPGTTPITPVLTS 4714

Query: 484  SSYVSIASNSTFTGTSGIQTQARLP 508
            ++    A++S  T +S  +T   LP
Sbjct: 4715 TATTPAATSSKATSSSSPRTATTLP 4739



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 101/425 (23%), Positives = 151/425 (35%), Gaps = 55/425 (12%)

Query: 42   TELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQK 101
            TE      +     STAT  ST             A   T+  + +  +  P   + L  
Sbjct: 3168 TEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPA 3227

Query: 102  LG--AQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHS 159
            L   A TP   S   I  + +  T+  +L +QT  P      ++T   S +P  +   H+
Sbjct: 3228 LRSTATTPTATSVTAIPSSSLG-TAWTRL-SQTTTPTAT---MSTATPSSTPETV---HT 3279

Query: 160  QLPQAQKVTTQAQSGDAKLPPQ--------QIKVVTIGGRPEVKPVIGVSALTPGSQLIN 211
                    TT   +G    P          ++   T  G          +ALTP    I+
Sbjct: 3280 STVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP-PVWIS 3338

Query: 212  TTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
            TTT P    T +  TV  +  P T  +  V+T         S A    +TQ S       
Sbjct: 3339 TTTTP----TTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTS------- 3387

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISP-LKSPNKAVKSTVQTITVGG 330
                 TP  PS T T +     GST N ++ TP    I P L +      +T  T+T   
Sbjct: 3388 ----GTP--PSLTTTATTITATGSTTNPSS-TPGTTPIPPVLTTTATTPAATSSTVTPSS 3440

Query: 331  VSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSS-------TQP---VSQNP 380
               +     +P  TA       +P S  H VR    TSA+S        T+P    S  P
Sbjct: 3441 ALGTTHTPPVPNTTA-TTHGRSLPPSSPHTVR-TAWTSATSGILGTTHITEPSTVTSHTP 3498

Query: 381  STNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQ---RLI 437
            +  T   Q + P +  ++P   S    S  +     P     TS+   T+ P +     +
Sbjct: 3499 AATTSTTQHSTPAL--SSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTL 3556

Query: 438  MPATP 442
            +P++P
Sbjct: 3557 LPSSP 3561



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 78/340 (22%), Positives = 116/340 (34%), Gaps = 35/340 (10%)

Query: 12   LPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATP------ISTEP 65
            +P   + T  T +   +     +S+  P  T   E V+ ++   +TAT       ++T  
Sbjct: 2543 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTP--ETVHTSTVLTTTATTTGATGSVATPS 2600

Query: 66   ITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSD 125
             T  + HT +V   TT        T   A PS         PV IS       + S  + 
Sbjct: 2601 STPGTAHTTKVLTTTT--------TGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTP 2652

Query: 126  LKLGNQTLKPDGQKLILTTLGK------SGSPIVLALPHSQLPQAQKVTTQAQSGDAKLP 179
              +   T  P       TT+        S S      P S    A  +T    + +    
Sbjct: 2653 SSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSST 2712

Query: 180  PQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIA-KKPRT--- 235
            P    +  +       P    S +TP S L  T T P    T       ++   P T   
Sbjct: 2713 PGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRT 2772

Query: 236  ----PTSGPVITKLIFAKPINSK---AVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITIS 288
                 TSG + T  I      +    A T  TTQ S P ++    S  T  +P    T +
Sbjct: 2773 AWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTT 2832

Query: 289  ESGVIGSTLNSTTQTPNKIAISPL--KSPNKAVKSTVQTI 326
                  ++  + T TP+K   S L   SP  A  +TV T+
Sbjct: 2833 PGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTM 2872



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 72/304 (23%), Positives = 105/304 (34%), Gaps = 27/304 (8%)

Query: 184  KVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSG--PV 241
            K+ T     E        + TPG+  I   T+PS   T  + T   A    T  +   P 
Sbjct: 3698 KLTTTATTTESTGSTATPSSTPGTTWI--LTEPSTTATVTVPTGSTATASSTQATAGTPH 3755

Query: 242  ITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKT-ITISESGVIGST---- 296
            ++       + S   T  +   SP         +ST  TP+ T  T   S  +G+T    
Sbjct: 3756 VSTTATTPTVTSSKATPFS---SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRL 3812

Query: 297  LNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGS 356
              +TT T      +P  +P  A  STV T T    + +      P +T       +VP +
Sbjct: 3813 SQTTTPTATMSTATPSSTPETAHTSTVLT-TTATTTRATGSVATPSSTPGTAHTTKVPTT 3871

Query: 357  KFHYVRLVTATS-ASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQV 415
                  +  ++S  ++ T PV    ST T P      V  ++ P     P V       V
Sbjct: 3872 TTTGFTVTPSSSPGTARTPPVW--ISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTV 3929

Query: 416  VPKPINPTSQIVTTSQPQQRLIMPATPL--------PQIQPNLTNLPP---GTVLAPAPG 464
                +   S    TS     LI  AT +        P   P  T +PP    T   PA  
Sbjct: 3930 ATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT 3989

Query: 465  TGNV 468
            +  V
Sbjct: 3990 SSTV 3993



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 74/337 (21%), Positives = 113/337 (33%), Gaps = 31/337 (9%)

Query: 12   LPEEIMDTGITLVDDDSIEAVIVSSPIPMET----ELEEIVNINSTGDSTATPISTEPIT 67
            +P   + T  T +   +     +S+  P  T        ++   +T       ++T   T
Sbjct: 3800 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSST 3859

Query: 68   VYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLK 127
              + HT +V   TT     +  TV P+   G  +     PV IS         S  +   
Sbjct: 3860 PGTAHTTKVPTTTT-----TGFTVTPSSSPGTART---PPVWISTTTTPTTSGSTVTPSS 3911

Query: 128  LGNQTLKPDGQKLILTTLGK------SGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQ 181
            +   T  P       TT+        S S      P S +  A  +T    + +    P 
Sbjct: 3912 VPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPG 3971

Query: 182  QIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIA-KKPRT----- 235
               +  +       P    S +TP S L  T T P    T       ++   P T     
Sbjct: 3972 TTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAW 4031

Query: 236  --PTSGPVITKLIFAKPINSK---AVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISES 290
               TSG + T  I      +    A T  TTQ S P ++    S  T  +P    T +  
Sbjct: 4032 TSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 4091

Query: 291  GVIGSTLNSTTQTPNKIAISPL--KSPNKAVKSTVQT 325
                ++  + T TP+K   S L   SP  A  +TV T
Sbjct: 4092 HTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVT 4128



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 83/340 (24%), Positives = 115/340 (33%), Gaps = 49/340 (14%)

Query: 28   SIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADS 87
            S+ A+  SS     T L +     +T  STATP ST P TV   HT+ V   TT T   +
Sbjct: 3239 SVTAIPSSSLGTAWTRLSQTTTPTATM-STATPSST-PETV---HTSTVLTTTTTTTRAT 3293

Query: 88   NTTVKP---------------------AFPSGLQKLGAQTPVTISANQIILNKVSQTSDL 126
             +   P                     A PS         PV IS       + S  +  
Sbjct: 3294 GSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPS 3353

Query: 127  KLGNQTLKPDGQKLILTTLGK------SGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPP 180
             +   T          TT+        S S      P S    A  +T    + +    P
Sbjct: 3354 SIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTP 3413

Query: 181  QQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTP---- 236
                +  +       P    S +TP S L  T T P  +      T   +  P +P    
Sbjct: 3414 GTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP--VPNTTATTHGRSLPPSSPHTVR 3471

Query: 237  ------TSGPVITKLIFAKPI---NSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITI 287
                  TSG + T  I        ++ A T  TTQ S P ++    S  T  +P    T 
Sbjct: 3472 TAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTT 3531

Query: 288  SESGVIGSTLNSTTQTPNKIAISPL--KSPNKAVKSTVQT 325
            +     G++  + T TP+K   S L   SP  A  +TV T
Sbjct: 3532 TPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVT 3571



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 69/289 (23%), Positives = 101/289 (34%), Gaps = 37/289 (12%)

Query: 204  TPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSG--PVITKLIFAKPINSKAVTGQTT 261
            TPG+  I   T+PS   T  + T   A    T  +   P ++       + S   T  + 
Sbjct: 2461 TPGTTWI--LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFS- 2517

Query: 262  QVSPPVIAGRVLSQSTPGTPSKT-ITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVK 320
              SP         +ST  TP+ T  T   S  +G+T    +QT    A     +P+    
Sbjct: 2518 --SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS---- 2571

Query: 321  STVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNP 380
            ST +T+    V T+   T    AT         PG+  H  +++T T+   +  P S +P
Sbjct: 2572 STPETVHTSTVLTTTATT--TGATGSVATPSSTPGTA-HTTKVLTTTTTGFTATP-SSSP 2627

Query: 381  ----------STNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTS 430
                      ST T P  +   V  ++ P     P V       V    +   S    TS
Sbjct: 2628 GTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTS 2687

Query: 431  QPQQRLIMPATPL--------PQIQPNLTNLPP---GTVLAPAPGTGNV 468
                 L   AT +        P   P  T +PP    T   PA  +  V
Sbjct: 2688 GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTV 2736



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 63/280 (22%), Positives = 102/280 (36%), Gaps = 16/280 (5%)

Query: 233  PRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRV-LSQSTPGT--PSKTITISE 289
            P TP +    T    + P  +  +T QTT  +     G   +  STPGT  P K +T + 
Sbjct: 2975 PSTPATSSTATPS--STPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTA 3032

Query: 290  SGVIGSTLNSTTQTPNKIAISPLKSPNKAVKST------VQTITVGGVSTSQFKTIIPLA 343
            +    ++  +T+ +  + A +     + A KST      + + T+G   T   +T  P+A
Sbjct: 3033 TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMA 3092

Query: 344  TAPNVQQIQVPGSKFHYVRL---VTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPV 400
            T   +     P +      L    T T A+SS    S  P T T  L +       T   
Sbjct: 3093 TMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGT-TWILTELTTAATTTAAT 3151

Query: 401  RMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLA 460
              +    S      ++ +P    +  V T          AT         T   P  + +
Sbjct: 3152 GPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISS 3211

Query: 461  PAPGTGNVGYA-VLPAQYVTQLQQSSYVSIASNSTFTGTS 499
             A  + + G A  LPA   T    ++    A  S+  GT+
Sbjct: 3212 RATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTA 3251



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 73/314 (23%), Positives = 112/314 (35%), Gaps = 54/314 (17%)

Query: 31   AVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTT 90
            +V   S  P      ++    +TG  TATP S+ P T     T  V ++TT T     +T
Sbjct: 2038 SVATPSSTPGTAHTTKVPTTTTTG-FTATP-SSSPGTAL---TPPVWISTTTTPTTRGST 2092

Query: 91   VKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGS 150
            V P+   G       T +T +   +    ++  S     + T  P       TT+  +GS
Sbjct: 2093 VTPSSIPGTTHTA--TVLTTTTTTVATGSMATPSSSTQTSGT--PPSLTTTATTITATGS 2148

Query: 151  --------------PIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGR--PEV 194
                          P++     +    +  VT  +  G    PP    + T  GR  P  
Sbjct: 2149 TTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPS 2208

Query: 195  KPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSK 254
             P    +A T  +  I  TT  +              +P T TS             ++ 
Sbjct: 2209 SPHTVRTAWTSATSGILGTTHIT--------------EPSTVTS-------------HTL 2241

Query: 255  AVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPL-- 312
            A T  TTQ S P ++    S  T  +P    T +      ++  + T TP+K   S L  
Sbjct: 2242 AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLP 2301

Query: 313  KSPNKAVKSTVQTI 326
             SP  A  +TV T+
Sbjct: 2302 SSPTSAPITTVVTM 2315



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 55/266 (20%), Positives = 91/266 (34%), Gaps = 38/266 (14%)

Query: 264  SPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTV 323
            S P  +   +  STPGT   T  ++E     +T  ST  T    +      P K + S  
Sbjct: 4233 STPATSSTAMPSSTPGT---TWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPA 4289

Query: 324  QTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTN 383
             T               P AT+        P          TAT+    T   +++ +T+
Sbjct: 4290 TT---------------PTATSSKATSSSSPR---------TATTLPVLTSTATKSTATS 4325

Query: 384  TQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPL 443
              P+  +      T P + + P+ +   +          TS ++TT     R    +T  
Sbjct: 4326 VTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTR-ATSSTST 4384

Query: 444  PQIQPN----LTNLPPGTVLAPAPG-TGNVGYAVLPAQYVTQLQQSSYVSIASNSTFT-- 496
            P   P     LT L        A G T            +T+L  ++  + ++ ST T  
Sbjct: 4385 PSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS 4444

Query: 497  ---GTSGIQTQARLPFNGIIPSESAS 519
               GT+ I T+        +P+ S +
Sbjct: 4445 STPGTTWILTEPSTTATVTVPTGSTA 4470



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 74/316 (23%), Positives = 105/316 (33%), Gaps = 60/316 (18%)

Query: 235  TPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGT------PSKTITI- 287
            TP+S P  T  I  K   +   T  T   + P         STPGT      PS T T+ 
Sbjct: 3685 TPSSTPG-TTWILTKLTTTATTTESTGSTATP--------SSTPGTTWILTEPSTTATVT 3735

Query: 288  -------------SESGVIGSTLNSTTQTPNKIAISPLKSPN-----KAVKSTVQTIT-- 327
                         + +G    +  +TT T      +P  SP       A++ST  T T  
Sbjct: 3736 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTAT 3795

Query: 328  ---------VGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQ 378
                     +G   T   +T  P AT         P +      L T  + + +T  V+ 
Sbjct: 3796 SFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVAT 3855

Query: 379  NPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIM 438
              ST   P       V  TT    +V   S+    +  P  I+ T+   T+         
Sbjct: 3856 PSST---PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSG-------- 3904

Query: 439  PATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGT 498
             +T  P   P  T+ P  TVL     T   G    P+   TQ   +    I + +T T T
Sbjct: 3905 -STVTPSSVPGTTHTP--TVLTTTTTTVATGSMATPSS-STQTSGTPPSLITTATTITAT 3960

Query: 499  SGIQTQARLPFNGIIP 514
                  +  P    IP
Sbjct: 3961 GSTTNPSSTPGTTPIP 3976


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 112/477 (23%), Positives = 175/477 (36%), Gaps = 73/477 (15%)

Query: 16   IMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINST----GDSTATPISTEPITVYSN 71
            I  T  +L    S   ++VSS     T L   V +++T    G STATP    P  V   
Sbjct: 1424 ISTTSPSLQVPTSTSEIVVSS-----TALYPSVTVSATSASAGGSTATPGPKPPAVVSQQ 1478

Query: 72   HTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQ------TPV---TISANQIILNKVSQ 122
                  V  T+T   + T    +FPS   +L  Q      TP    T+  +   L+K S 
Sbjct: 1479 AAGSTTVGATLTSVSTTT----SFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSH 1534

Query: 123  TSDLKLGNQTLKPDGQKL----ILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKL 178
            +S   L      P         + + + + G    L +P S +     +   A      L
Sbjct: 1535 SSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIP-SVIASTPILPQAAGPTSTPL 1593

Query: 179  PPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQ---QLKTVQIAKKPRT 235
             PQ   +      P V+PV  V A+     LI++  QP++L  Q       V    +P+ 
Sbjct: 1594 LPQVPSI-----PPLVQPVANVPAVQ--QTLIHSQPQPALLPNQPHTHCPEVDSDTQPKA 1646

Query: 236  PTSGPVIT-----KLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISES 290
            P    + T     + +F++  +S A     +  +  VI   V    TPG P  T  ++ S
Sbjct: 1647 PGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTV----TPGIP--TTAVAPS 1700

Query: 291  GVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQ 350
             ++ ST  ST   P  + +  +  P   V +  Q  T    +TS  K      TAP+   
Sbjct: 1701 KLLTST-TSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKP----GTAPSKPP 1755

Query: 351  IQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVV-VNTTPVRMSVPIVSA 409
            +                   +   PV       T P +Q  P    + T  +  +  + A
Sbjct: 1756 L-----------------TKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDA 1798

Query: 410  QAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTG 466
            Q  + + P+ I  TS +   S      I  A   P  Q  ++ +  G VLA + G G
Sbjct: 1799 QLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQP--QKGVSQVKEGPVLATSSGAG 1853



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 107/503 (21%), Positives = 180/503 (35%), Gaps = 63/503 (12%)

Query: 9    NSLLPEEIMDT-GITLVDDDSIEAVIVSSPIPMETELEEIVNINST-GDSTATP--ISTE 64
            + + P EI DT   +      +     +S + ++    E+     T G +TA P    T 
Sbjct: 1271 SKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTG 1330

Query: 65   P-ITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQT 123
            P   V     + +A   T   A +      + P+ +     Q+ VT+   + I    + T
Sbjct: 1331 PTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATST 1390

Query: 124  SDLKLGNQTLKPDGQKLILTTLGKSGS-PIVLALPHSQLPQAQKVTTQAQ---SGDAKLP 179
              +  G   + P  +  +L+++  S + P V+++  +  P  Q  T+ ++   S  A  P
Sbjct: 1391 GVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTS-PSLQVPTSTSEIVVSSTALYP 1449

Query: 180  PQQIKVVTI--GGR---PEVKPVIGVS-----ALTPGSQLINTTTQPSVLQTQQLKTVQI 229
               +   +   GG    P  KP   VS     + T G+ L + +T  S   T    ++Q+
Sbjct: 1450 SVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQL 1509

Query: 230  AKKPRTPT-SGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITIS 288
            +    TPT +  V+         +  + TG    +S P       S S+PG    +    
Sbjct: 1510 SSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPS------SSSSPGAGVSSYISQ 1563

Query: 289  ESG----VIGSTLNSTTQTPNKIA--ISPLKSPNKAVKSTVQTIT-VGGVSTSQFKTIIP 341
              G    VI S + ST   P       +PL     ++   VQ +  V  V  +   +   
Sbjct: 1564 PGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQ 1623

Query: 342  LATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVS---QNPSTNTQPLQQAKPVVVNTT 398
             A  PN      P                S TQP +    +  T  + L+       ++ 
Sbjct: 1624 PALLPNQPHTHCP-------------EVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSG 1670

Query: 399  PVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATP--LPQIQPNLTNLPPG 456
                SV + ++  ++  V      T  I TT+    +L+   T   LP      TNLP G
Sbjct: 1671 AQHASVSLETSLVIESTV------TPGIPTTAVAPSKLLTSTTSTCLPP-----TNLPLG 1719

Query: 457  TVLAPAPGTGNVGYAVLPAQYVT 479
            TV  P       G    P    T
Sbjct: 1720 TVALPVTPVVTPGQVSTPVSTTT 1742



 Score = 37.0 bits (84), Expect = 0.067
 Identities = 85/389 (21%), Positives = 135/389 (34%), Gaps = 54/389 (13%)

Query: 28   SIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADS 87
            S+  V  S PI    + + I         TA P  T   ++    T+  A          
Sbjct: 726  SLTGVSSSQPIQHPQQQQGI-------QQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQ 778

Query: 88   NTTVKPAFPSGLQKLGAQTPVTISAN-QIILNKVSQTSDLKLGNQTLKPDGQKLILTTLG 146
               V P   +G Q   +Q   TI    QI +        +  G   L P GQ L      
Sbjct: 779  APQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFL-PVGQPL------ 831

Query: 147  KSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPG 206
               +P++   P SQ+P +    + AQ+G + LP     +    G  +    +  SA T  
Sbjct: 832  --PTPLLPQYPVSQIPISTPHVSTAQTGFSSLP-----ITMAAGITQPLLTLASSATTAA 884

Query: 207  SQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPP 266
               ++T   PS L T      Q+  +       P +      + +   A  GQ  +V  P
Sbjct: 885  IPGVSTVV-PSQLPTLLQPVTQLPSQVHPQLLQPAV------QSMGIPANLGQAAEV--P 935

Query: 267  VIAGRVLSQS-----TPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKS 321
            + +G VL Q       P  P  +     S V    ++ST  +P      P+ +   A   
Sbjct: 936  LSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSP------PMPTEVLATPG 989

Query: 322  TVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSA-SSSTQPVSQNP 380
               T+    V ++    ++P+       Q+  PG         ++  A   STQ VSQ  
Sbjct: 990  YFPTVVQPYVESN---LLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQ-- 1044

Query: 381  STNTQPLQQAKPVVVNTTPVRMSVPIVSA 409
                  +  A+PV V  T       + S+
Sbjct: 1045 ------VAPAEPVAVAQTQATQPTTLASS 1067



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 19/133 (14%)

Query: 255 AVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKS 314
           AVTG+T +          + + + G  + T T        S +  +  T  ++   PL  
Sbjct: 46  AVTGRTEEYRR---RRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSL 102

Query: 315 PNKAVKSTV---------QTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVT 365
           P  ++ + V         +  TV   +TSQ     P A AP  Q +  P          T
Sbjct: 103 PQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPS-------T 155

Query: 366 ATSASSSTQPVSQ 378
             S++S  +PVSQ
Sbjct: 156 VPSSTSKDRPVSQ 168


>gi|98986457 host cell factor 1 [Homo sapiens]
          Length = 2035

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 89/397 (22%), Positives = 151/397 (38%), Gaps = 69/397 (17%)

Query: 91  VKPAFPSGLQKL--GAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGK- 147
           V+P    G+  L   A  P T +  Q++      +  +    +T    G   +L   G  
Sbjct: 437 VQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAART---QGVPAVLKVTGPQ 493

Query: 148 --SGSPIVLALPHSQLPQAQKVTTQAQSGDAKL-PPQQIKVVTIGGRPEVKPVIGVSALT 204
             +G+P+V   P SQ  +A    T   +G   + P Q  +   IG  P++  +  ++A  
Sbjct: 494 ATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAA 553

Query: 205 PGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVS 264
             +Q I  ++ P+VL                  +G  I K +   P       G TT  +
Sbjct: 554 AATQKIPPSSAPTVLSV---------------PAGTTIVKTMAVTP-------GTTTLPA 591

Query: 265 PPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQ 324
              +A   +  S P T    +  + +  +G++++S T T  +  I+  KS    V    Q
Sbjct: 592 TVKVASSPVMVSNPAT---RMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648

Query: 325 TIT--VGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPST 382
            +T  VGGV+ +     I L  +P    I VPG       L    S    T+PV  +  T
Sbjct: 649 VVTTVVGGVTKT-----ITLVKSP----ISVPGGSALISNLGKVMSV-VQTKPVQTSAVT 698

Query: 383 ---NTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQ----- 434
              +T P+ Q          ++   P+ +   +K V      PT+ I+TT+Q        
Sbjct: 699 GQASTGPVTQI---------IQTKGPLPAGTILKLVTSADGKPTT-IITTTQASGAGTKP 748

Query: 435 -----RLIMPATPLPQIQPNLTNLPPGTVLAPAPGTG 466
                  + P+T  P     +  +P   ++  A  TG
Sbjct: 749 TILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATG 785



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 84/383 (21%), Positives = 144/383 (37%), Gaps = 54/383 (14%)

Query: 61  ISTEPITVYSNHTNQVA-----VNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQI 115
           +++ P+ V +  T  +      V T+++ A +NT+ +P     + K G    VT++    
Sbjct: 595 VASSPVMVSNPATRMLKTAAAQVGTSVSSA-TNTSTRPIIT--VHKSGT---VTVAQQAQ 648

Query: 116 ILNKV--SQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQS 173
           ++  V    T  + L    +   G   +++ LGK  S +          Q + V T A +
Sbjct: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVV----------QTKPVQTSAVT 698

Query: 174 GDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQ--LKTVQIAK 231
           G A   P    + T G  P    +  V++       I TTTQ S   T+   L    ++ 
Sbjct: 699 GQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSP 758

Query: 232 KPRTPTSGPVITKLIFAKPINSKAVTGQTTQV---SPPVIAGRVLSQSTPGTPSKTITIS 288
               P +  +I  +  +  I     TG T+     SP  I    +  S  G P+K IT  
Sbjct: 759 STTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAV 818

Query: 289 ESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNV 348
                G      TQ         LK       + ++T+ +GGV      T+   A  P V
Sbjct: 819 PKIATGHGQQGVTQVV-------LKGAPGQPGTILRTVPMGGVRLVTPVTVS--AVKPAV 869

Query: 349 QQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVS 408
             + V G+      L T T   S++   +   ST+                  ++ PI +
Sbjct: 870 TTLVVKGTT-GVTTLGTVTGTVSTSLAGAGGHSTSAS----------------LATPITT 912

Query: 409 AQAVKQVVPKPINPTSQIVTTSQ 431
              +  +  + INPT+  V+ +Q
Sbjct: 913 LGTIATLSSQVINPTAITVSAAQ 935


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 101/497 (20%), Positives = 165/497 (33%), Gaps = 52/497 (10%)

Query: 42   TELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQK 101
            TEL       ++  STATP ST             A   T T + + ++  P   + L  
Sbjct: 4724 TELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPV 4783

Query: 102  LGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQL 161
            L      T +A +     V+      LG     P+     + T+            H+  
Sbjct: 4784 L------TSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTST 4837

Query: 162  PQAQKVTTQAQSGDAKLPPQQ-------IKVVTIGGRPEVKPVIGVSALTPGSQLINTTT 214
                K TT   +     P           ++ T              + TPG+  I T  
Sbjct: 4838 VLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEL 4897

Query: 215  QPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLS 274
                  T    T        TP+S P  T  I  +P  +  VT  T        A    +
Sbjct: 4898 ------TTTATTTASTGSTATPSSTPGTT-WILTEPSTTATVTVPTGST-----ATASST 4945

Query: 275  QSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKS----PNKAVKSTVQTITVGG 330
            Q+T GTP  + T +   V  S    ++      A+  L+S    P     + + + ++G 
Sbjct: 4946 QATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGT 5005

Query: 331  VSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQA 390
              T   +T  P AT         P    H   ++TAT+ ++        PS+        
Sbjct: 5006 TWTRLSQTTTPTATMSTATPSSTP-ETVHTSTVLTATATTTGATGSVATPSSTPGTAHTT 5064

Query: 391  KPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQ---QRLIMPATPLPQIQ 447
            K     TT    +       A+      P++  S I T+S P+      ++  T      
Sbjct: 5065 KVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRA 5124

Query: 448  PNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFT-----GTSGIQ 502
             N T  P  T+     GT  +         +T+L  ++  + A+ ST T     GT+ I 
Sbjct: 5125 TNSTATPSSTL-----GTTRI---------LTELTTTATTTAATGSTATLSSTPGTTWIL 5170

Query: 503  TQARLPFNGIIPSESAS 519
            T+       ++P+ S +
Sbjct: 5171 TEPSTIATVMVPTGSTA 5187



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 91/410 (22%), Positives = 145/410 (35%), Gaps = 58/410 (14%)

Query: 42   TELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQK 101
            TEL        +  STATP ST                TT    + +TT     P+G   
Sbjct: 3075 TELTTTATTTESTGSTATPSSTP--------------GTTWILTEPSTTATVTVPTGSTA 3120

Query: 102  LGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQL 161
              + T  T     +     + T           P G    L  L +S +    A   + +
Sbjct: 3121 TASSTQATAGTPHVSTTATTPTVTSSKATPFSSP-GTATALPAL-RSTATTPTATSFTAI 3178

Query: 162  PQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPE---VKPVIGVSALTPGS--QLINTTTQP 216
            P +   TT  +      P   +   T    PE      V+  +A T G+   +   ++ P
Sbjct: 3179 PSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTP 3238

Query: 217  SVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQ---VSPPVIAGRVL 273
                T ++ T        TP+S P   + +   P+     T  TT+   V+P  I G   
Sbjct: 3239 GTAHTTKVLTTTTTGFTATPSSSPGTARTL---PVWISTTTTPTTRGSTVTPSSIPG--- 3292

Query: 274  SQSTPGTPSKTITISESGVIGSTLNSTTQT---------PNKIAISPLKSPNKAVKSTVQ 324
            +  TP   + T T   +G + +T +S+TQT         PN  A +  +S + +   TV+
Sbjct: 3293 TTHTPTVLTTTTTTVATGSM-ATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVR 3351

Query: 325  TITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNT 384
            T      S +   T I   T P+      P +        T T+  S+    S +PS+ T
Sbjct: 3352 TAWTSATSGTLGTTHI---TEPSTGTSHTPAA-------TTGTTQHSTPALSSPHPSSRT 3401

Query: 385  QPLQQAKPVVVNTTP-----VRMSVPIVSAQAVKQVVPKPINPTSQIVTT 429
                ++ P    TTP        +    +    +     P +PTS  +TT
Sbjct: 3402 ---TESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITT 3448



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 89/407 (21%), Positives = 147/407 (36%), Gaps = 73/407 (17%)

Query: 56   STATPISTEPITVYSNHTNQVAVNTTIT--KADSNTTVKPAFPSGLQKLGAQTPVTISAN 113
            STATP ST   T         A  T  T   A   +T++ A P  +    A TP   S+ 
Sbjct: 2586 STATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSK 2645

Query: 114  QIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQS 173
                     T     G  T  P  +    T    S +PI         P +   TT  + 
Sbjct: 2646 A--------TPSSSPGTATALPALRSTATTPTATSVTPI---------PSSSLGTTWTRL 2688

Query: 174  GDAKLPPQQIKVVTIGGRPEV---KPVIGVSALTPGS--QLINTTTQPSVLQTQQLKTVQ 228
                 P   +   T    PE      V+  +A T G+   +   ++ P    T ++ T  
Sbjct: 2689 SQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTT 2748

Query: 229  IAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITIS 288
                  TP+S P                    T ++PPV    + + +TP T   T+T  
Sbjct: 2749 TTGFTATPSSSP-------------------GTALTPPVW---ISTTTTPTTRGSTVT-- 2784

Query: 289  ESGVIGSTLNST--TQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAP 346
             S + G+T  +T  T T   +A   + +P+ + +++  T T    +T        +AT  
Sbjct: 2785 PSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNT--------MAT-- 2834

Query: 347  NVQQIQVPGSKFHYVRL--VTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSV 404
                  +P S  H VR    +ATS    T  +++  +  +  L        ++TP  +S 
Sbjct: 2835 -THGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPA-LSS 2892

Query: 405  PIVSAQAVKQ------VVPKPINPTSQIVTTSQPQQ---RLIMPATP 442
            P  S++  +         P     TS+   T+ P +     ++P++P
Sbjct: 2893 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSP 2939



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 101/426 (23%), Positives = 154/426 (36%), Gaps = 83/426 (19%)

Query: 42   TELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQK 101
            TEL       +    TATP ST   T      +  A  T  T + +  +   A    L+ 
Sbjct: 3719 TELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKV 3778

Query: 102  LG--AQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHS 159
            L   A TP  IS+          T     G  T  P  +    T    S    V A+P S
Sbjct: 3779 LTSTATTPTVISSRA--------TPSSSPGTATALPALRSTATTPTATS----VTAIPSS 3826

Query: 160  QLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGS--QLINTTTQPS 217
             L  A    +Q  +                      P   +S  TP S  + ++T+T  +
Sbjct: 3827 SLGTAWTRLSQTTT----------------------PTATMSTATPSSTPETVHTSTVLT 3864

Query: 218  VLQTQQLKTVQIAKKPRTP-----TSGPVITKLIF-AKPINSKAVTGQTTQVSPPVIAGR 271
               T    T  +A    TP     T  P  T   F A P +S       T ++PPV    
Sbjct: 3865 TTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPG-----TALTPPVW--- 3916

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNST--TQTPNKIAISPLKSPNKAVKSTVQTITVG 329
            + + +TP T   T+T   S + G+T  +T  T T   +A   + +P+ + +++  T T  
Sbjct: 3917 ISTTTTPTTRGSTVT--PSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHT-- 3972

Query: 330  GVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSS-------TQP---VSQN 379
                      +P  TA       +P S  H VR    TSA+S        T+P    S  
Sbjct: 3973 --------PPVPNTTA-TTHGRSLPPSSPHTVR-TAWTSATSGILGTTHITEPSTVTSHT 4022

Query: 380  PSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQ---RL 436
            P+  T   Q + P +  ++P   S    S  +     P     TS+   T+ P +     
Sbjct: 4023 PAATTSTTQHSTPAL--SSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTST 4080

Query: 437  IMPATP 442
            ++P++P
Sbjct: 4081 LLPSSP 4086



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 78/310 (25%), Positives = 112/310 (36%), Gaps = 44/310 (14%)

Query: 28   SIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADS 87
            S+ A+  SS     T L +     +T  STATP ST P TV   HT+ V   TT T   +
Sbjct: 3819 SVTAIPSSSLGTAWTRLSQTTTPTATM-STATPSST-PETV---HTSTVLTTTTTTTRAT 3873

Query: 88   NTTVKPAFPSGLQ---KLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTT 144
             +   P+   G     K+   T    +A        + T  + +   T          TT
Sbjct: 3874 GSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTP--------TT 3925

Query: 145  LGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALT 204
             G + +P  +             TT   +G    P    +     G     PV   +A T
Sbjct: 3926 RGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQT---SGTTHTPPVPNTTATT 3982

Query: 205  PGSQLINTTTQPSVLQTQQ-------LKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVT 257
             G  L    + P  ++T         L T  I + P T TS             ++ A T
Sbjct: 3983 HGRSL--PPSSPHTVRTAWTSATSGILGTTHITE-PSTVTS-------------HTPAAT 4026

Query: 258  GQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPL--KSP 315
              TTQ S P ++    S  T  +P    T +     G++  + T TP+K   S L   SP
Sbjct: 4027 TSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSP 4086

Query: 316  NKAVKSTVQT 325
              A  +TV T
Sbjct: 4087 TSAPITTVVT 4096



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 71/289 (24%), Positives = 104/289 (35%), Gaps = 38/289 (13%)

Query: 184  KVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSG--PV 241
            K+ T     E        + TPG+  I   T+PS   T  + T   A    T  +   P 
Sbjct: 4223 KLTTTATTTESTGSTATPSSTPGTTWI--LTEPSTTATVTVPTGSTATASSTQATAGTPH 4280

Query: 242  ITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKT-ITISESGVIGST---- 296
            ++       + S   T  +   SP         +ST  TP+ T  T   S  +G+T    
Sbjct: 4281 VSTTATTPTVTSSKATPFS---SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRL 4337

Query: 297  LNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGS 356
              +TT T      +P  +P  A  STV T T    +T++       AT         PG+
Sbjct: 4338 SQTTTPTATMSTATPSSTPETAHTSTVLTTT---ATTTR-------ATGSVATPSSTPGT 4387

Query: 357  KFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVV 416
              H  ++ T T+   +  P S +P T   P     PV ++TT    + P  S   V    
Sbjct: 4388 A-HTTKVPTTTTTGFTVTP-SSSPGTARTP-----PVWISTT----TTPTTSGSTVTPSS 4436

Query: 417  PKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGT 465
                  T  ++TT+         ATP    Q + T   P     P P T
Sbjct: 4437 VPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTP-----PVPNT 4480



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 63/280 (22%), Positives = 102/280 (36%), Gaps = 16/280 (5%)

Query: 233  PRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRV-LSQSTPGT--PSKTITISE 289
            P TP +    T    + P  +  +T QTT  +     G   +  STPGT  P K +T + 
Sbjct: 3555 PSTPATSSTATPS--STPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTA 3612

Query: 290  SGVIGSTLNSTTQTPNKIAISPLKSPNKAVKST------VQTITVGGVSTSQFKTIIPLA 343
            +    ++  +T+ +  + A +     + A KST      + + T+G   T   +T  P+A
Sbjct: 3613 TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMA 3672

Query: 344  TAPNVQQIQVPGSKFHYVRL---VTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPV 400
            T   +     P +      L    T T A+SS    S  P T T  L +       T   
Sbjct: 3673 TMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGT-TWILTELTTAATTTAAT 3731

Query: 401  RMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLA 460
              +    S      ++ +P    +  V T          AT         T   P  + +
Sbjct: 3732 GPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISS 3791

Query: 461  PAPGTGNVGYA-VLPAQYVTQLQQSSYVSIASNSTFTGTS 499
             A  + + G A  LPA   T    ++    A  S+  GT+
Sbjct: 3792 RATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTA 3831



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 79/323 (24%), Positives = 117/323 (36%), Gaps = 56/323 (17%)

Query: 12   LPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATP------ISTEP 65
            +P   + T  T +   +     +S+  P  T   E V+ ++   +TAT       ++T  
Sbjct: 3178 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTP--ETVHTSTVLTTTATTTGATGSVATPS 3235

Query: 66   ITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSD 125
             T  + HT +V   TT        T   A PS         PV IS       + S  + 
Sbjct: 3236 STPGTAHTTKVLTTTT--------TGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTP 3287

Query: 126  LKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKV 185
              +   T  P     +LTT   + +   +A P S        +TQ  SG    PP     
Sbjct: 3288 SSIPGTTHTPT----VLTTTTTTVATGSMATPSS--------STQT-SGTTHTPPVPNTT 3334

Query: 186  VTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKL 245
             T  GR          +L+P S     T   S   +  L T  I + P T TS       
Sbjct: 3335 ATTHGR----------SLSPSSPHTVRTAWTSAT-SGTLGTTHITE-PSTGTS------- 3375

Query: 246  IFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPN 305
                  ++ A T  TTQ S P ++    S  T  +P    T +      ++  + T TP+
Sbjct: 3376 ------HTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPS 3429

Query: 306  KIAISPL--KSPNKAVKSTVQTI 326
            K   S L   SP  A  +TV T+
Sbjct: 3430 KTRTSTLLPSSPTSAPITTVVTM 3452



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 75/320 (23%), Positives = 113/320 (35%), Gaps = 52/320 (16%)

Query: 12   LPEEIMDTGITLVDDDSIEAVIVSSPIPMET----ELEEIVNINSTGDSTATPISTEPIT 67
            +P   + T  T +   +     +S+  P  T        ++   +T       ++T   T
Sbjct: 4325 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSST 4384

Query: 68   VYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLK 127
              + HT +V   TT     +  TV P+   G  +     PV IS         S  +   
Sbjct: 4385 PGTAHTTKVPTTTT-----TGFTVTPSSSPGTART---PPVWISTTTTPTTSGSTVTPSS 4436

Query: 128  LGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVT 187
            +   T  P     +LTT   + +   +A P S        +TQ  SG    PP      T
Sbjct: 4437 VPGTTHTPT----VLTTTTTTVATGSMATPSS--------STQT-SGTTHTPPVPNTTAT 4483

Query: 188  IGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIF 247
              GR          +L+P S     T   S   +  L T  I + P T TS         
Sbjct: 4484 THGR----------SLSPSSPHTVRTAWTSAT-SGTLGTTHITE-PSTGTS--------- 4522

Query: 248  AKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKI 307
                ++ A T  TTQ S P ++    S  T  +P    T +      ++  + T TP+K 
Sbjct: 4523 ----HTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKT 4578

Query: 308  AISPL--KSPNKAVKSTVQT 325
              S L   SP  A  +TV T
Sbjct: 4579 RTSTLLPSSPTSAPITTVVT 4598



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 62/265 (23%), Positives = 94/265 (35%), Gaps = 21/265 (7%)

Query: 204  TPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSG--PVITKLIFAKPINSKAVTGQTT 261
            TPG+  I   T+PS   T  + T   A    T  +   P ++       + S   T  + 
Sbjct: 3096 TPGTTWI--LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFS- 3152

Query: 262  QVSPPVIAGRVLSQSTPGTPSKT-ITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVK 320
              SP         +ST  TP+ T  T   S  +G+T    +QT    A     +P+    
Sbjct: 3153 --SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS---- 3206

Query: 321  STVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNP 380
            ST +T+    V T+   T    AT         PG+  H  +++T T+   +  P S   
Sbjct: 3207 STPETVHTSTVLTTTATT--TGATGSVATPSSTPGTA-HTTKVLTTTTTGFTATPSSSPG 3263

Query: 381  STNTQPL---QQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLI 437
            +  T P+       P    +T    S+P  +              T  + T S   Q   
Sbjct: 3264 TARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG 3323

Query: 438  MPATPLPQIQPNLTNLPPGTVLAPA 462
               TP     PN T    G  L+P+
Sbjct: 3324 TTHTP---PVPNTTATTHGRSLSPS 3345



 Score = 37.0 bits (84), Expect = 0.067
 Identities = 68/283 (24%), Positives = 98/283 (34%), Gaps = 43/283 (15%)

Query: 56   STATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQ---KLGAQTPVTISA 112
            STATP ST P T    HT+ V   T  T   + +   P+   G     K+   T    +A
Sbjct: 2699 STATPSST-PETA---HTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTA 2754

Query: 113  NQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQ 172
                    + T  + +   T          TT G + +P  +             TT   
Sbjct: 2755 TPSSSPGTALTPPVWISTTTTP--------TTRGSTVTPSSIPGTTHTATVLTTTTTTVA 2806

Query: 173  SGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQ-------LK 225
            +G    P    +     G     PV    A T G  L    + P  ++T         L 
Sbjct: 2807 TGSMATPSSSTQT---SGTTHTPPVPNTMATTHGRSL--PPSSPHTVRTAWTSATSGILG 2861

Query: 226  TVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTI 285
            T  I + P T TS             ++ A T  TTQ S P ++    S  T  +P    
Sbjct: 2862 TTHITE-PSTVTS-------------HTLAATTGTTQHSTPALSSPHPSSRTTESPPSPG 2907

Query: 286  TISESGVIGSTLNSTTQTPNKIAISPL--KSPNKAVKSTVQTI 326
            T +      ++  + T TP+K   S L   SP  A  +TV T+
Sbjct: 2908 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTM 2950



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 70/298 (23%), Positives = 101/298 (33%), Gaps = 60/298 (20%)

Query: 235  TPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGT------PSKTITI- 287
            TP+S P  T  I  K   +   T  T   + P         STPGT      PS T T+ 
Sbjct: 4210 TPSSTPG-TTWILTKLTTTATTTESTGSTATP--------SSTPGTTWILTEPSTTATVT 4260

Query: 288  -------------SESGVIGSTLNSTTQTPNKIAISPLKSPN-----KAVKSTVQTIT-- 327
                         + +G    +  +TT T      +P  SP       A++ST  T T  
Sbjct: 4261 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTAT 4320

Query: 328  ---------VGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQ 378
                     +G   T   +T  P AT         P +      L T  + + +T  V+ 
Sbjct: 4321 SFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVAT 4380

Query: 379  NPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIM 438
              ST   P       V  TT    +V   S+    +  P  I+ T+   T+         
Sbjct: 4381 PSST---PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSG-------- 4429

Query: 439  PATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFT 496
             +T  P   P  T+ P  TVL     T   G    P+   TQ   +++     N+T T
Sbjct: 4430 -STVTPSSVPGTTHTP--TVLTTTTTTVATGSMATPSS-STQTSGTTHTPPVPNTTAT 4483


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 85/334 (25%), Positives = 126/334 (37%), Gaps = 68/334 (20%)

Query: 179  PPQQIKVVTIGGRP-EVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPT 237
            PP   ++ T G RP +V P+ G S  T    L +T   PS   T           P +PT
Sbjct: 1204 PPTTPQLPTTGSRPTQVWPMTGTS--TTIGLLSSTGPSPSSNHT-----------PASPT 1250

Query: 238  SGPVI-TKLIFAKPINSKAVTGQ-TTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGS 295
              P++   L  +KP  S     + TT V+P   +G       P T +   T ++  V  +
Sbjct: 1251 QTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSG------LPPTATLRSTATKPTVTQA 1304

Query: 296  TLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPG 355
            T  +T  T +    S  +S      +T  T+T+   +TS     +P +T       ++PG
Sbjct: 1305 TTRATASTASPATTSTAQS------TTRTTMTLPTPATSGTSPTLPKSTNQ-----ELPG 1353

Query: 356  SKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQ----- 410
            +        T T+    T P S    T  QP Q  +P    TT  R +    + Q     
Sbjct: 1354 TT------ATQTTGPRPT-PASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTT 1406

Query: 411  ----AVKQVVPK--PINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPG 464
                     VP   P+  TS   TT+ P      P T LP      T++PP +     P 
Sbjct: 1407 HSPPTAGSPVPSTGPVTATSFHATTTYPTPS--HPETTLP------THVPPFSTSLVTPS 1458

Query: 465  TGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGT 498
            T  V         +T        S +++S  TGT
Sbjct: 1459 THTV---------ITPTHAQMATSASNHSAPTGT 1483



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 99/514 (19%), Positives = 175/514 (34%), Gaps = 51/514 (9%)

Query: 3    VVPAEVNSLLPEEIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPIS 62
            + P   ++  P   + T  T     S      S+ +   T       + ST  ++ TP  
Sbjct: 1714 ITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNH 1773

Query: 63   TEPITVYSNHTNQVAVNTTITKA---DSNTTVKPAFPSGLQKLGAQTPVTISANQIILNK 119
            T   T        VA  T+ T +      TT  P  P+G   + +  PVT ++ Q     
Sbjct: 1774 TSTGT-----RTPVAHTTSATSSRLPTPFTTHSP--PTGTTPISSTGPVTATSFQ----- 1821

Query: 120  VSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLP 179
             + T        T  P       T+L    +  V+   H+Q+  A   +  +       P
Sbjct: 1822 TTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQM--ATSASIHSMPTGTIPP 1879

Query: 180  PQQIKVV-TIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTS 238
            P  IK   +    P + P    ++ +P S     T+      T      ++     TPTS
Sbjct: 1880 PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEV-----TPTS 1934

Query: 239  GPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLN 298
               IT    +    ++     TT  S   +     + S P   S     S +G + +T  
Sbjct: 1935 TTNITPKHTST--GTRTPVAHTTSASSSRLPTPFTTHSPPTGSSP---FSSTGPMTATSF 1989

Query: 299  STT---------QTPNKIAISPLKSPNKAVKS-TVQTITVGGVSTSQFKTIIPLATAPNV 348
             TT         QT     + P  +      + TV   T   ++TS      P  T P  
Sbjct: 1990 QTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPP 2049

Query: 349  QQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVS 408
              ++  GS      +   TS +S T       + ++  +  +  +  N++    S PI +
Sbjct: 2050 TTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT 2109

Query: 409  AQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAP---APGT 465
                      P++ T+Q+ ++  P           P     +++  P +  +P   +P  
Sbjct: 2110 QLPHLSSATTPVSTTNQLSSSFSPS----------PSAPSTVSSYVPSSHSSPQTSSPSV 2159

Query: 466  GNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTS 499
            G     V    + T L   S+ S++++ T    S
Sbjct: 2160 GTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 98/491 (19%), Positives = 167/491 (34%), Gaps = 64/491 (13%)

Query: 51   NSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADS-NTTVKPAFPSGLQKLGAQTPVT 109
            ++TG +T  P   +P    +  T Q    T  T   + +TT  P  P+    + +  PVT
Sbjct: 1368 STTGPTTPQP--GQPTRPTATETTQTRTTTEYTTPQTPHTTHSP--PTAGSPVPSTGPVT 1423

Query: 110  ISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTT 169
             ++        + T       +T  P       T+L    +  V+   H+Q+  A   + 
Sbjct: 1424 ATSFH-----ATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQM--ATSASN 1476

Query: 170  QAQSGDAKLPPQQIKVV-TIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQ 228
             +       PP  +K   +    P + P    S  +      +T   P+ L +    T  
Sbjct: 1477 HSAPTGTIPPPTTLKATGSTHTAPPITPT--TSGTSQAHSSFSTNKTPTSLHSHTSST-- 1532

Query: 229  IAKKPRTPTSGPVITKLIFAKPINSK-----AVTGQTTQVSPPVIAGRVLSQSTPGTPSK 283
                   P   P  T  I   P +++     A T   T   PP         +T   P+ 
Sbjct: 1533 -----HHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPP------PFTTHSPPTG 1581

Query: 284  TITISESGVIGSTLNSTT---------QTPNKIAISPLKSPNKAVKS-TVQTITVGGVST 333
            +   S +G + +T   TT         QT     + P  +      + TV T T   ++T
Sbjct: 1582 SSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMAT 1641

Query: 334  SQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASS------STQPVSQNPSTNTQPL 387
            S     +P  T P    ++  GS      +   TS +S      +T   S +  ++T   
Sbjct: 1642 SASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSST 1701

Query: 388  QQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRL----------I 437
              A+    +TT +  + P  +      V     + +    +T++    L           
Sbjct: 1702 HHAEATSTSTTNITPN-PTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPE 1760

Query: 438  MPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTG 497
            + +T    I PN T+    T   P   T +   + LP  + T    +    I+S    T 
Sbjct: 1761 VTSTSTTSITPNHTSTGTRT---PVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTA 1817

Query: 498  TSGIQTQARLP 508
            TS  QT    P
Sbjct: 1818 TS-FQTTTTYP 1827


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 111/514 (21%), Positives = 188/514 (36%), Gaps = 79/514 (15%)

Query: 29   IEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSN 88
            +  + V  P P++  +  +V+        + P     I   +       V+   +   S 
Sbjct: 1223 VRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPST 1282

Query: 89   TTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLG-- 146
            T   PA P+GL        + ++ANQ+    V+ T  +K+  +    DG   +       
Sbjct: 1283 T---PA-PTGLS-------LPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAP 1331

Query: 147  ---KSGSPIVL----ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIG 199
                SG P VL     L   +LP     T +A      L    +K+V         P   
Sbjct: 1332 RPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVH-------SPSPE 1384

Query: 200  VSALTPGSQLINTTTQ---PSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAV 256
            VSA  PG+  +  ++    PS L       + I     +P + PV + +  + P++S   
Sbjct: 1385 VSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNS--SPLASPVSSTV--SVPLSSSLP 1440

Query: 257  TGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPN 316
                T +  P  A   +  S P      +T+S SG    T           +++P  +P 
Sbjct: 1441 ISVPTTLPAPASAPLTIPISAP------LTVSASGPALLT-----------SVTPPLAPV 1483

Query: 317  KAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATS----ASSS 372
                    ++   G S S     + LATAP++   Q PG   H + L   +S     +S+
Sbjct: 1484 VPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPG---HPLLLAPTSSHVPGLNST 1540

Query: 373  TQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQP 432
              P           L    P   N  P + S+ +  A +  Q +  P+ P       + P
Sbjct: 1541 VAPACSPVLVPASALASPFPSAPNPAPAQASL-LAPASSASQALATPLAP------MAAP 1593

Query: 433  QQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNV---GYAVLPAQYVTQLQQSSYVS- 488
            Q  ++ P +P P + P    LP   VLAP+PG   V       +P    +    +S  S 
Sbjct: 1594 QTAILAP-SPAPPLAP----LP---VLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASA 1645

Query: 489  --IASNSTFTGTSGIQTQARLPFNGIIPSESASR 520
              + + +     S  QT    P    +PS ++++
Sbjct: 1646 SPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQ 1679


>gi|163965366 nascent polypeptide-associated complex alpha subunit
           isoform a [Homo sapiens]
          Length = 2078

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 94/391 (24%), Positives = 140/391 (35%), Gaps = 43/391 (10%)

Query: 94  AFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSP-I 152
           AFP  L        V  S + I L+     S+ K     L     +++    G    P I
Sbjct: 152 AFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTN---LNKVPSEVVPNPKGTPSPPCI 208

Query: 153 VLALP-HSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPV----IGVSALTPGS 207
           V  +P H   P A       QSG A LP            P+VK      + +S   PGS
Sbjct: 209 VSTVPYHCVTPMAS-----IQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGS 263

Query: 208 QLINTTTQPSV---LQTQQLKTVQIAKK---PRTPTSGPVITKLIFA----KPINSKAVT 257
             +     P     L TQ L  V  ++K   P TP   P+      A        S  + 
Sbjct: 264 LSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLL 323

Query: 258 GQT--TQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSP 315
           GQT  + +S P +    +  S+ G        S+  VI    +     P  +A  P+ +P
Sbjct: 324 GQTGPSALSDPTVKTISVDHSSTGASYP----SQRSVIPPLPSRNEVVPATVAAFPVVAP 379

Query: 316 N-KAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQ 374
           +     ST+ +IT     +    T   L+   ++     P + +HY  +     +S  T 
Sbjct: 380 SVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTT 439

Query: 375 P-VSQNPSTNTQPLQQAKPVVVNTTPVRMSVPI-----VSAQAVKQVVPKPINPTSQIVT 428
           P V  NP T          V    +P   S PI      S  A+      P  P++Q+ T
Sbjct: 440 PLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVAT 499

Query: 429 TSQPQQRLIMPATPLPQIQPNLTNLPPGTVL 459
           T      L +P +P      +L NLP   ++
Sbjct: 500 T------LRIPVSPPLPDPEDLKNLPSSVLV 524



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 85/346 (24%), Positives = 116/346 (33%), Gaps = 62/346 (17%)

Query: 157  PHSQLPQAQKVTTQA-QSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQ 215
            PH   P    VT  + + G A  PP+          P  K   G      G+      T 
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP-PKGAPTPPAVTP 1340

Query: 216  PSVLQTQQLKTVQIAKK--PRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVL 273
            PS   T  L     + K  P TP+S                   G T   + P   G   
Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKE-----------------GPTPPAATPSHKGG-- 1381

Query: 274  SQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVST 333
               TP +P +          G  + S    P   A+ PL SP KA  + V   T  G +T
Sbjct: 1382 PAMTPPSPKR----------GPAIPSPKGDPTSPAVIPL-SPKKAPATPV---TREGAAT 1427

Query: 334  SQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQ---- 389
                 + P A  P V   + P +        T +S    T P    PS    P  +    
Sbjct: 1428 PSKGDLTPPAVTP-VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486

Query: 390  -AKPVVVNTTPVRMSVPIVSA--QAVKQVVP-------KPINPTSQIVT-----TSQPQQ 434
             + P     TP  M  P + A   +  + VP        PI PT+ +++     T  P++
Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546

Query: 435  RLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGY---AVLPAQY 477
             LI PA  +P   P  T   P    APA  +        AV P+ Y
Sbjct: 1547 ALIPPAMTVP--SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 76/354 (21%), Positives = 128/354 (36%), Gaps = 71/354 (20%)

Query: 187 TIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLI 246
           T+ G P     + + AL P S   ++   P++L +    +V +A+      SG VIT   
Sbjct: 126 TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP--SVAVAE------SGSVITLSA 177

Query: 247 FAKP---------INSKAVTGQTTQVSPPVIAGRV--------------LSQSTPGTPSK 283
              P         + S+ V       SPP I   V              ++     TP+ 
Sbjct: 178 PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTT 237

Query: 284 TITISESGVIGSTLNS---TTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTII 340
           T+ I+   V  +T++S   + Q P  +++    SP  A+  + Q++    V TS  KT  
Sbjct: 238 TLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLP---VVTSSQKTAG 294

Query: 341 PLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPV 400
           P  T P+                    S  S   P+ Q+   + Q L Q       T P 
Sbjct: 295 P-NTPPDF-----------------PISLGSHLAPLHQSSFGSVQLLGQ-------TGPS 329

Query: 401 RMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPAT--PLPQIQPNLTNLPPGTV 458
            +S P V   +V         P+ + V    P +  ++PAT    P + P++   P    
Sbjct: 330 ALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTIS 389

Query: 459 LAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGI 512
                 +G++  A       T    S   S+   S+   T      A++P + +
Sbjct: 390 SITCSPSGSLNVA-------TSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSV 436


>gi|224458301 family with sequence similarity 186, member A [Homo
            sapiens]
          Length = 2351

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 87/386 (22%), Positives = 149/386 (38%), Gaps = 44/386 (11%)

Query: 84   KADSNTTVKPAFPSGLQKLGAQTPVTISAN-QIILNKVSQTSDLKLGNQTLKPDGQKLIL 142
            K      +K   P  L+K+  QTP+T+S   + +L  V ++ + K   + LK       L
Sbjct: 983  KTKDQMQMKETQPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLK------TL 1036

Query: 143  TTLGKSGSPIVLALPHS---QLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIG 199
              L     PI +  P S    LP A  ++ Q  +    L PQQ + V I   P+     G
Sbjct: 1037 ENLPDEKEPISITPPPSLQYSLPGALPISGQPLTKCIHLTPQQAQEVGITLTPQQAQAQG 1096

Query: 200  VSALTPGSQLINTTTQPSVLQT-------QQLKTVQIAKKP-RTPTSGPVITKLIFAKPI 251
            ++     +Q +     P   Q        QQ + + I   P +T   G  +T      P 
Sbjct: 1097 ITLTLQQAQELGIPLTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQDQAP- 1155

Query: 252  NSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKT------ITISESGVIGSTLNSTTQTPN 305
                 T Q  ++  P+   +  +   P TP +       +T  ++  +  +L        
Sbjct: 1156 GISLTTQQAQKLGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQQAQEL 1215

Query: 306  KIAISPLKSPNKAVKSTVQTITVGGV--STSQFKTIIPLATAPNVQQIQVPGSKFHYVRL 363
             I ++P ++    +  T+Q     G+  +  Q + +    T   VQ++ +P +      L
Sbjct: 1216 GIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQELGIPLTPQQAQAL 1275

Query: 364  -VTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVR---MSVPIVSAQAVKQVVPKP 419
             +T T   +    +  NP       QQA+ + +  TP +   + +P    QA  Q +  P
Sbjct: 1276 GITLTPKQAQELGIPLNP-------QQAQTLGIPLTPKQAQALGIPFTPQQA--QALGIP 1326

Query: 420  INP----TSQIVTTSQPQQRLIMPAT 441
            + P    T +I  T Q  Q L MP T
Sbjct: 1327 LTPQQAQTQEITLTPQQAQALGMPLT 1352



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 88/404 (21%), Positives = 145/404 (35%), Gaps = 42/404 (10%)

Query: 58   ATPISTEPITVYSNHTNQVA--VNTTITKADSNTTVKPAFPSGLQKLGAQ-TPVTISANQ 114
            A PIS +P+T   + T Q A  V  T+T   +            Q+LG   TP    A +
Sbjct: 1061 ALPISGQPLTKCIHLTPQQAQEVGITLTPQQAQAQGITLTLQQAQELGIPLTPQQAQALE 1120

Query: 115  IILN-KVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQS 173
            I+   + +Q   + L  Q  +  G              I L     Q P     T QAQ 
Sbjct: 1121 ILFTPQQAQALGIPLTPQQTQVQG--------------ITLTPQQDQAPGISLTTQQAQK 1166

Query: 174  GDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKP 233
                L PQQ + + I   P+    +G+      +Q +  +  P     QQ + + I   P
Sbjct: 1167 LGIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTP-----QQAQELGIPLTP 1221

Query: 234  RTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSK------TITI 287
            +   +  +   L  A+ +       Q   +   +   +V     P TP +      T+T 
Sbjct: 1222 QQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQELGIPLTPQQAQALGITLTP 1281

Query: 288  SESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVS-TSQFKTIIPLATAP 346
             ++  +G  LN        I ++P ++    +  T Q     G+  T Q      +   P
Sbjct: 1282 KQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQQAQALGIPLTPQQAQTQEITLTP 1341

Query: 347  NVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPL--QQAKPVVVNTTPVR--- 401
              QQ Q  G     + L T  +         Q+      PL  QQA+ + +  TP +   
Sbjct: 1342 --QQAQALG-----MPLTTQQAQELGIPLTPQHAQALGMPLTTQQAQELGIPLTPQQAQA 1394

Query: 402  MSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQ 445
            + +P+ + QA +  +P       ++     PQQ      T  PQ
Sbjct: 1395 LGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQ 1438



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 99/471 (21%), Positives = 168/471 (35%), Gaps = 84/471 (17%)

Query: 11   LLPEEIMDTGITLVDDDSIEAVIVSSP-------IPMETELEEIVNINSTGDSTATPIST 63
            L P++    GITL    + E  I  +P       IP+  +  + + I  T          
Sbjct: 1267 LTPQQAQALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPFTPQQAQA--LG 1324

Query: 64   EPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQ-TPVTISA-NQIILNKVS 121
             P+T     T ++    T+T   +     P      Q+LG   TP    A    +  + +
Sbjct: 1325 IPLTPQQAQTQEI----TLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMPLTTQQA 1380

Query: 122  QTSDLKLGNQTLKPDGQKLILTTLGKSGSPIV------LALPHS-QLPQAQKVTT----- 169
            Q   + L  Q  +  G  L      + G P+       L +P + Q  QAQ++T      
Sbjct: 1381 QELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEITLTPQQA 1440

Query: 170  ----------QAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVL 219
                      QAQ     L PQQ + + I   P+    +G+  + P +Q +     P   
Sbjct: 1441 QALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIPLTPQ-- 1498

Query: 220  QTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPG 279
            Q Q L  + I   P+    G  +T    A+ +    +  Q  ++  P+   +V +   P 
Sbjct: 1499 QAQALGILLI--PPQAQELGIPLTPQ-QAQALGIPLIPPQAQELGIPLTPQQVQALGIPL 1555

Query: 280  TPSKT------ITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVST 333
             P +       +T  ++  +G  L         I ++P ++    +  T Q     G   
Sbjct: 1556 IPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQELGIPLTPQQAQAQG--- 1612

Query: 334  SQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPV 393
                  IPL      QQ Q  G        ++ T   +  Q ++  P       QQA+ +
Sbjct: 1613 ------IPLTP----QQAQALG--------ISLTPQQAQAQGITLTP-------QQAQAL 1647

Query: 394  VVNTTPVRMSVPIVSAQAVK-QVVPKPINPTSQIVTTSQPQQRLIMPATPL 443
             V  TPV   V  V+  + +   +  P+N         Q Q++L+    PL
Sbjct: 1648 GVPITPVNAWVSAVTLTSEQTHALESPMN-------LEQAQEQLLKLGVPL 1691


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 118/542 (21%), Positives = 198/542 (36%), Gaps = 67/542 (12%)

Query: 5     PAEVNSLLPEEI-------MDTGITL-VDDDSIEAVIVSSPIPMETELEEIVN--INSTG 54
             PAE N+++P           DT + + +     EA    S   +  ++ ++V   + S+G
Sbjct: 11495 PAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSG 11554

Query: 55    DSTATPISTEPITVYSNHTNQVAVNTTITK-ADSNTTVKPAFPSGLQKLGAQTPVTISAN 113
               T+T   T   T Y   T      T +T  A+++TTV    P+   +     P  +++ 
Sbjct: 11555 TDTSTTFPTLSETPYEPETTA----TWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSP 11610

Query: 114   QIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQS 173
              +       T+       T+ P    ++ + +  S +    A+P +  P   +  T A S
Sbjct: 11611 GVDTRSGVPTT-------TIPPSIPGVVTSQVTSSATDTSTAIP-TLTPSPGEPETTASS 11662

Query: 174   GDAKLPPQQIK-VVTIGGRPEVKPVIGVSALT--PGSQLINTTTQPSVLQTQQLKTVQIA 230
               A  P  Q    V I   P  +P    S +T  P +    + T  S   +    T  +A
Sbjct: 11663 --ATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMA 11720

Query: 231   KKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISES 290
               PRT  S  V+T +    P   + VT Q T               +PG P  T  +S  
Sbjct: 11721 TSPRTEASSAVLTTISPGAP---EMVTSQITSSGAATSTTVPTLTHSPGMPETTALLST- 11776

Query: 291   GVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVG-GVSTSQFKTIIPLATAPNVQ 349
                    +  T+T       P  +    V  T  ++T+  G  TS   T +P  T  ++ 
Sbjct: 11777 -------HPRTETSKTF---PASTVFPQVSETTASLTIRPGAETS---TALPTQTTSSLF 11823

Query: 350   QIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQ---PLQQAKPVVVNTT---PVRMS 403
              + V G+    +    +   S+ T P+S +P T T    P       ++ TT       S
Sbjct: 11824 TLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSS 11883

Query: 404   VPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQI----QPNLTNLPPGTVL 459
                 ++     V P     +S  +TT +PQ          P +     P  +    GT +
Sbjct: 11884 AETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTGTTM 11943

Query: 460   A------PAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGII 513
                    P P   + G  V P    T + +++ V  A+N   TG+S    +    FN + 
Sbjct: 11944 TLIPSEMPTPPKTSHGEGVSP----TTILRTTMVE-ATNLATTGSSPTVAKTTTTFNTLA 11998

Query: 514   PS 515
              S
Sbjct: 11999 GS 12000



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 98/462 (21%), Positives = 173/462 (37%), Gaps = 47/462 (10%)

Query: 15   EIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTN 74
            E+  +G T +   S   V+        T L     +  + + T  P  T P    S  T 
Sbjct: 6987 EVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTI-PTQTGPSGSTSQDTL 7045

Query: 75   QVAVNTTITKADSNTTVKPAFP-SGLQKLGAQTPVTIS--ANQIILNKVSQTSDLKLGNQ 131
             +  +TT ++A +++T+   FP S +  L ++ P  +S  ++  + N  S  S L L   
Sbjct: 7046 TLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPAT 7105

Query: 132  TLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQ---SGDAKLPPQQIKVVTI 188
            T  P     +  T+  S  P+   L  S +     + T  +   S   KL     + +T 
Sbjct: 7106 TSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTT 7165

Query: 189  G----GRPEVKPVIGVSAL----------TPGSQLINTTTQPS-----VLQTQQLKTVQI 229
            G        V P    +A           +P S L ++ T  +     +  TQ+  TV I
Sbjct: 7166 GKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAI 7225

Query: 230  AKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPG-----TPSKT 284
            +      TS   I K   +        TG + + S  +    VLS+ + G     + ++ 
Sbjct: 7226 STPHFLETSR--IQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEV 7283

Query: 285  ITISESGVIGSTLN------STTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKT 338
             + S + + GS  +      STT+   K   SP+ + +  +    QT   G  S S F T
Sbjct: 7284 TSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTF-T 7342

Query: 339  IIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQP-VSQNPSTNTQP--LQQAKPVVV 395
            +    T   V        +  +  + T  S  +   P  S  P   T P   Q +   ++
Sbjct: 7343 LDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMI 7402

Query: 396  NTTPVRMSVPI----VSAQAVKQVVPKPINPTSQIVTTSQPQ 433
            + +PV  ++P      SA     + P  +  T  +  +++P+
Sbjct: 7403 SPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPE 7444



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 84/413 (20%), Positives = 160/413 (38%), Gaps = 56/413 (13%)

Query: 40   METELEEIVNINST-GDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSG 98
            M  +++++   N    D  ++P S  P+ V +   + VA         S  ++     S 
Sbjct: 4724 MNNDVKDVSQTNPPFQDEASSPSSQAPVLV-TTLPSSVAFTPQWHSTSSPVSMSSVLTSS 4782

Query: 99   LQKLGAQTPVTI----SANQII---LNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSP 151
            L K   +   ++    S+ Q +   L+ +S TS      +T  P     ++T +G +GS 
Sbjct: 4783 LVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPS-INTVVTNVGTTGSA 4841

Query: 152  IVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLIN 211
                   S  P+  KVT+        +    ++  TI             ++   S+   
Sbjct: 4842 FESHSTVSAYPEPSKVTSP------NVTTSTMEDTTIS-----------RSIPKSSKTTR 4884

Query: 212  TTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGR 271
            T T+ +   T +L+   I+++         IT       +  K +TG TT+VS   +   
Sbjct: 4885 TETETTSSLTPKLRETSISQE---------ITSSTETSTVPYKELTGATTEVSRTDVTSS 4935

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
              S S PG    T++          L+ +T+T  +++ SP+ + +  +  T QT   G  
Sbjct: 4936 S-STSFPGPDQSTVS----------LDISTETNTRLSTSPIMTESAEITITTQTGPHGAT 4984

Query: 332  STSQFKTIIPLATAPNVQQIQVPGSKFH-YVRLVTATSASSSTQPVSQNPSTNTQPLQQA 390
            S   F T+ P  T P   Q  +  +  H + +L   T  S   Q VS     +    + +
Sbjct: 4985 SQDTF-TMDPSNTTP---QAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVD--KTS 5038

Query: 391  KPVVVNTTPVRMSVPIVSAQAVKQVVPKPINP--TSQIVTTSQPQQRLIMPAT 441
             P    ++P   +  ++S+   +  +  P+    TS +V  +   +  + P T
Sbjct: 5039 SPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVT 5091



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 91/437 (20%), Positives = 174/437 (39%), Gaps = 47/437 (10%)

Query: 22  TLVDDDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTT 81
           TL  + +   V     +P ET   E       GDST TP  T  I V      +   ++T
Sbjct: 148 TLTVETTSGPVTEKYTVPTETSTTE-------GDSTETPWDTRYIPVKITSPMKTFADST 200

Query: 82  ITKADSNTTVKPAFPSGLQKL--GAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQK 139
            +K ++  ++ PA  +       G   P   +     L+   + +    G  +L+     
Sbjct: 201 ASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDLSPKGTPNSRGETSLE----- 255

Query: 140 LILTTLGKS-GSPIVLALPHSQLPQAQKVTTQAQSGDAKLPP------QQIKVVTIGGRP 192
           LIL+T G    SP   +  HS++  +  +++ A   D K+        Q +      G P
Sbjct: 256 LILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVP 315

Query: 193 EVKPVIGVSALTPGSQLINT--TTQPSVLQT-QQLKTVQIAKKPRTPTSGPVITKLIFAK 249
           E +     ++  P S  ++   T+   V  T   L T  I+ K    T   ++T   FA+
Sbjct: 316 EARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAET---ILTFHAFAE 372

Query: 250 PINSKAVTGQTTQVS-----PPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTP 304
            ++  +     T  S     P  + G   S  T  +PS T+   E+    ST    T+  
Sbjct: 373 TMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGT 432

Query: 305 NKIAISPLK--SPNKAVKSTVQTITVGGVST--SQFKTIIPLATAPNVQQIQVPGSKFHY 360
              +++PL+  +P +  + T   +   G +T  S+ ++   ++++   ++++  GS    
Sbjct: 433 LNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSG- 491

Query: 361 VRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVP-----IVSAQAVKQV 415
            R  ++T+A  S+  +    S+ +    +A      +T  + S P     + ++ ++K  
Sbjct: 492 -RQSSSTAAHGSSDILRATTSSTS----KASSWTSESTAQQFSEPQHTQWVETSPSMKTE 546

Query: 416 VPKPINPTSQIVTTSQP 432
            P      +  +TTS P
Sbjct: 547 RPPASTSVAAPITTSVP 563



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 54/240 (22%), Positives = 92/240 (38%), Gaps = 40/240 (16%)

Query: 165  QKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIG-VSALTPGSQLINTTTQPSVLQT-- 221
            Q +T+     D    P    ++T      +    G   A T G  L++T+T P + +T  
Sbjct: 4358 QFITSTNTFTDVSTNPSTSLIMTESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETPL 4417

Query: 222  -------QQLKTVQIAKKPRTP--TSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRV 272
                   Q  KT  I+K P+    TS P + +  +   +    VT       PP  A   
Sbjct: 4418 AVTPDFMQSEKTTLISKGPKDVSWTSPPSVAETSYPSSLTPFLVT-----TIPP--ATST 4470

Query: 273  LSQSTPGTPSKTITISESGVIGST-LNSTTQTPNKIAISPLKSPNKAVKSTVQTIT-VGG 330
            L      +P    ++  SG++ +T + +T+  P   +   L +P+  + +T+   T +  
Sbjct: 4471 LQGQHTSSPVSATSVLTSGLVKTTDMLNTSMEPVTNSPQNLNNPSNEILATLAATTDIET 4530

Query: 331  VSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQA 390
            +  S  K +  + TA +   +                    ST PVS  PST T P+  A
Sbjct: 4531 IHPSINKAVTNMGTASSAHVLH-------------------STLPVSSEPSTATSPMVPA 4571



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 105/511 (20%), Positives = 186/511 (36%), Gaps = 81/511 (15%)

Query: 5     PAEVNSLLPEEIMDTGITLVDDDSIEAVIVS------SPIPMETE---LEEIVNINSTGD 55
             PAE +S +P  I +   +  + D+  ++  S      S IP+ T     E++V    T  
Sbjct: 10687 PAETSSTIPRTIPN--FSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSS 10744

Query: 56    STATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPS-GLQKLGAQTPVTISANQ 114
              T   ++   +T+       +A   T  +A +++ +  +  S  + +L      +++A  
Sbjct: 10745 GTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAK- 10803

Query: 115   IILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIV----LALPHSQLPQAQKVTTQ 170
                   + T++  L N   +P    + L T     SP V        HS+      +TT 
Sbjct: 10804 ------TSTTNRALTNSPGEP-ATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTS 10856

Query: 171   --AQSGDAKLPPQQ-------IKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQT 221
               A+S  A   P         +  +    R  +   I +  L+PG       T PS+  +
Sbjct: 10857 HGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEP----ETTPSMATS 10912

Query: 222   QQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQV----------------SP 265
                   + +    TPT  P +  ++ +   +S+AVT  T  +                S 
Sbjct: 10913 HG---EEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSH 10969

Query: 266   PVIAGRVLSQSTPGTPS--KTITISESGVIGSTLNSTTQTPNKIAISP--LKSPNKAVKS 321
                AG  +    P  P    ++  S   V  +TL + T +P +   +P    S      S
Sbjct: 10970 GTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASS 11029

Query: 322   TVQTIT--VGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSS----TQP 375
             TV T++  V GV TS   +   + +      I  PG       + T+  A +S    T  
Sbjct: 11030 TVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPT 11089

Query: 376   VSQNPSTNTQPLQQAKPVVVNTT---------------PVRMSVPIVSAQAVKQVVPKPI 420
             VS   S    PL  +   V +TT                +  S  + ++ AV  V P+  
Sbjct: 11090 VSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVSPEVP 11149

Query: 421   NPTSQIVTTSQPQQRLIMPATPLPQIQPNLT 451
                + +VT+S+      +P   +   +P  T
Sbjct: 11150 GMVTSLVTSSRAVTSTTIPTLTISSDEPETT 11180



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 110/516 (21%), Positives = 190/516 (36%), Gaps = 81/516 (15%)

Query: 4    VPAEVNSLLPEEIMDTGITLVDDDSIEAVIVSSPIPMETELE----EIVNINST-----G 54
            V  +  S L  E+ +    LV + + E+  V S + ++   E    E+   + T      
Sbjct: 6066 VDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASA 6125

Query: 55   DSTATP-ISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLG---------- 103
             ST +P IS E  + +SN       +  +T +   T      PSG+  LG          
Sbjct: 6126 QSTKSPDISPEASSSHSN-------SPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIA 6178

Query: 104  --AQTPV----------TISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSP 151
              A TP           T S     LN V +TS               L++TT   S SP
Sbjct: 6179 TSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTT---SPSP 6235

Query: 152  IVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPE-VKPVIGVSALTPGSQLI 210
            +   L          VT+      AK+      +  +   P+ ++  +  S  T  +  +
Sbjct: 6236 VTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTM 6295

Query: 211  NTTTQPSVLQTQQLK-------TVQIAKKPRTPTSGPVITK------LIFAKPINS--KA 255
            + +   +V              TV     P   TS  VIT       +  + P +S  K 
Sbjct: 6296 HPSINTAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKK 6355

Query: 256  VTGQTT-----QVSPPVIAGRVLSQSTPGTP-SKTITISESGVIGSTLNSTTQTPNKIAI 309
            +  +TT     ++     + ++ S S   T   K  T + + V  + L S+++T  +   
Sbjct: 6356 IESETTFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTE 6415

Query: 310  SPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVT--AT 367
             P  SP+ + +S     T  G++ S+ +TI   AT     +    G+      + T  A 
Sbjct: 6416 KPTMSPDTSTRSVTMLSTFAGLTKSEERTI---ATQTGPHRATSQGTLTWDTSITTSQAG 6472

Query: 368  SASSSTQPVSQ-NPSTNTQPLQQ-----AKPVVVNTTPVR--MSVPIVSAQAVKQVVPKP 419
            + S+ T   SQ + ST T  + +     + P V  T+     +S+P +++ +        
Sbjct: 6473 THSAMTHGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTLPE 6532

Query: 420  INPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPP 455
              P+S +  TS P   L+     L  +     +LPP
Sbjct: 6533 SRPSSPVHLTSLPTSGLVKTTDMLASV----ASLPP 6564



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 105/504 (20%), Positives = 178/504 (35%), Gaps = 87/504 (17%)

Query: 5     PAEVNSLLPE----------EIMDTGITLVDDDSIEAVIVSSPIPMETELEEIVNINSTG 54
             PAE +S LP           + M + +T  + +S  A+  +    +   L  +V  +   
Sbjct: 11270 PAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRD 11329

Query: 55    DSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQ 114
              S   P   E     S H ++   +     A ++TTV    P+        TP   ++  
Sbjct: 11330 ISATFPTVPE-----SPHESEATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPG 11384

Query: 115   IILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTTQAQSG 174
                     TSD      T+ PD   ++ + +  SG+   + +P   L   +  TT +   
Sbjct: 11385 -----AEATSDFP--TITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFIT 11437

Query: 175   DAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQT---QQLKTVQIAK 231
              ++       + T+   P    ++    ++ G+   +TTT P++ +T    +   +Q+  
Sbjct: 11438 YSETHTSS-AIPTLPVSPGASKMLTSLVISSGTD--STTTFPTLTETPYEPETTAIQLIH 11494

Query: 232   KPRTPTSGPVIT-KLIFAK-------------PINSKAVTGQTTQVSP---PVIAGRVLS 274
                T T  P  T K   +K             P  S AV+  TT +SP    ++   V S
Sbjct: 11495 PAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVS--TTTISPDMSDLVTSLVPS 11552

Query: 275   ------------QSTPGTPSKTIT-----ISESGVIGSTLNSTTQTPNKIAISPLKSPNK 317
                           TP  P  T T        S  +  T+ + +   +  A S + SP  
Sbjct: 11553 SGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGV 11612

Query: 318   AVKSTVQTIT----VGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSST 373
               +S V T T    + GV TSQ  +     +         PG           T+ASS+T
Sbjct: 11613 DTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGE--------PETTASSAT 11664

Query: 374   QPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQ 433
              P +Q   T          V + T P      + S          P++ T+   + S P 
Sbjct: 11665 HPGTQTGFT----------VPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPD 11714

Query: 434   QRLIMPATPLPQIQPN-LTNLPPG 456
                +M  +P  +     LT + PG
Sbjct: 11715 ATPVMATSPRTEASSAVLTTISPG 11738



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 118/509 (23%), Positives = 176/509 (34%), Gaps = 62/509 (12%)

Query: 26   DDSIEAVIVSSPIPMETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKA 85
            D S E     S  P+ TE  EI     TG   AT   T  +   SN T Q  +++ +T  
Sbjct: 4951 DISTETNTRLSTSPIMTESAEITITTQTGPHGATSQDTFTMDP-SNTTPQAGIHSAMTHG 5009

Query: 86   DSN---TTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLIL 142
             S    TT+    P  +      +    S+    L+  + T+   L + TL  D     +
Sbjct: 5010 FSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTP-SLISSTLPEDKLSSPM 5068

Query: 143  TTLGKSG------------SPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGG 190
            T+L  SG             P+  +LP+      + + T   S D K     I       
Sbjct: 5069 TSLLTSGLVKITDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNV 5128

Query: 191  RPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKP 250
            +         S     S+    TTQ  +  T        A     P  G   T  I  +P
Sbjct: 5129 KANNSGHESHSPALADSETPKATTQMVITTT----VGDPAPSTSMPVHGSSETTNIKREP 5184

Query: 251  ---INSKAVTGQTTQVSP-PVIAGRVLSQSTPGTPSKTIT-ISESGVIGSTLNSTTQTPN 305
               +  +     T+Q S  P     +LS+     P+ TIT +S +GV  S+  ST     
Sbjct: 5185 TYFLTPRLRETSTSQESSFPTDTSFLLSK----VPTGTITEVSSTGVNSSSKISTPDHD- 5239

Query: 306  KIAISPLKSPNKAVKSTVQTITVGG----VSTSQFKTIIPLATAPNVQQIQVPGSKFHY- 360
                          KSTV   T  G    V TS  KT    A      Q   P S  H  
Sbjct: 5240 --------------KSTVPPDTFTGEIPRVFTSSIKT--KSAEMTITTQASPPESASHST 5283

Query: 361  VRLVTATSASSS------TQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQ 414
            + L T+T+ S        TQ    +  T    +       + T PV  +  + S  +   
Sbjct: 5284 LPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPA 5343

Query: 415  VV-PKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVL 473
            +  P P++ TS     S P     +P + L      L    P +V +  P   ++ +   
Sbjct: 5344 MTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHE-R 5402

Query: 474  PAQYVTQLQQSSYVSIASNSTFT--GTSG 500
            PA Y       + +  ++N+  T  GTSG
Sbjct: 5403 PATYKDTAHTEAAMHHSTNTAVTNVGTSG 5431



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 64/258 (24%), Positives = 104/258 (40%), Gaps = 30/258 (11%)

Query: 187  TIGGRPEVKPVIGVSALT--PGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITK 244
            +I  RPE       + LT  PG++ I+ T   S +  +++ +  I       TSGP I  
Sbjct: 1907 SIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEEVISTGI-------TSGPDINS 1959

Query: 245  LIFA-KPINSKAV----TGQTTQVSPPVIAGR-----VLSQSTPGTPSKTITISESGVIG 294
                  PI    +    TG   Q + P+ A       V +QSTP   S  ++ S +    
Sbjct: 1960 APMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENS 2019

Query: 295  STLNSTTQTPNKIA----ISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQ 350
             +  S+T +P   A    +    S   A+ S +  +T    +T+   T +  A +     
Sbjct: 2020 VSSGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSG 2079

Query: 351  IQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNT---TPVRMSVPIV 407
            +  P S      L +A S S++ Q   +NP T T   Q      +NT   +   +S   V
Sbjct: 2080 VSNPSSTTTEFPLFSAASTSAAKQ---RNPETETHGPQNTAASTLNTDASSVTGLSETPV 2136

Query: 408  SAQAVKQVVPKPINPTSQ 425
             A ++   VP P+  TS+
Sbjct: 2137 GA-SISSEVPLPMAITSR 2153



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 106/542 (19%), Positives = 209/542 (38%), Gaps = 64/542 (11%)

Query: 19   TGITLVDDDSIEAVIVSSPIPMETELEEI-VNINSTGDSTATPISTEPITVYSNHTNQVA 77
            T   L D  + +   V+SP+ + + +E+  V+ ++ G    + I TEP +  +    + +
Sbjct: 8071 TSFVLADSQTSK---VTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTS 8127

Query: 78   VNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDG 137
             +   + A   +TV    P+G     ++T VT S         S+TS       T+ P+ 
Sbjct: 8128 SSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSS---------SRTSISGFAQLTVSPET 8178

Query: 138  QKLILTTLGKSGSPIVLA--LPHSQLPQAQKVTTQAQSGDAKLPPQQIKV-VTIGGRPEV 194
                +T L  S      A  +  +Q            + D    P  ++   T+  R   
Sbjct: 8179 STETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSH 8238

Query: 195  KPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSK 254
              +  + + +PG  L    +Q SV +T    +  +   P T +  PV + L+   P  S 
Sbjct: 8239 SEMTTLVSRSPGDML--WPSQSSVEETSSASS--LLSLPATTSPSPVSSTLVEDFPSASL 8294

Query: 255  AVTGQTTQVSPPVI--AGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPN------- 305
             V   T+ ++P ++    R+     PGT S +   S S    +TL  T  T +       
Sbjct: 8295 PV---TSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHT 8351

Query: 306  -----KIAISPLKSPNKAV--KSTVQTITVGGVSTSQFKTIIPLATAPNVQ----QIQVP 354
                 + +IS  +S +  +    T +  +  G + +  +T + ++T+   +    QI+  
Sbjct: 8352 AVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPT 8411

Query: 355  GSKFHYVRLVTA----TSASSSTQPVSQNPSTNTQPLQQAKPVVVNTT----PVRMSV-P 405
             S    +R  ++    +SA+  +  +S+ PS  T  + + + +    T    P + ++ P
Sbjct: 8412 SSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTISP 8471

Query: 406  IVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATP------LPQIQPNLTNLPPGTVL 459
             +S +A+ ++       TS I+T S      I   +P         +  + T    GT  
Sbjct: 8472 DISTEAITRL------STSPIMTESAESAITIETGSPGATSEGTLTLDTSTTTFWSGTHS 8525

Query: 460  APAPGTGNVGYAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESAS 519
              +PG  +     L ++    +   S  S+   S+ + +          F   +P   +S
Sbjct: 8526 TASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISS 8585

Query: 520  RP 521
             P
Sbjct: 8586 SP 8587



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 78/374 (20%), Positives = 136/374 (36%), Gaps = 51/374 (13%)

Query: 41   ETELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQ 100
            +T +    + N   D   +P S   +T  S H  +  V+TT   A  +T +     +  Q
Sbjct: 3357 DTHVSLSTSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTT---AIPSTVLNNKIMAAEQ 3413

Query: 101  KLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPD-GQKLILTTLGKSGSPIVLALPHS 159
            +         S+     ++ S  SD+ LG     PD    L +T+  ++ S  +++LP  
Sbjct: 3414 QTSRSVDEAYSSTSSWSDQTS-GSDITLG---ASPDVTNTLYITSTAQTTS--LVSLPSG 3467

Query: 160  QLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPS-- 217
                 Q +T+       K         T        P IG+  L      + +   P+  
Sbjct: 3468 D----QGITSLTNPSGGK---------TSSASSVTSPSIGLETLRANVSAVKSDIAPTAG 3514

Query: 218  -VLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQS 276
             + QT     V I      PT G  I+  I     NS + T    +V      G     S
Sbjct: 3515 HLSQTSSPAEVSILDVTTAPTPG--ISTTITTMGTNSISTTTPNPEV------GMSTMDS 3566

Query: 277  TPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQF 336
            TP T  +T +        ST  S + T     ++ + S  K  +S     T+  + T+ F
Sbjct: 3567 TPATERRTTSTEHPSTWSSTAASDSWT-----VTDMTSNLKVARSPG---TISTMHTTSF 3618

Query: 337  KTIIPLATAPNVQQIQVPGSKFHYV--RLVTATSASSSTQPVSQNPSTNTQP--LQQAKP 392
                 LA++  +  +  P  +   +   LVT +S +S+ +  +        P     + P
Sbjct: 3619 -----LASSTELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTP 3673

Query: 393  VVVNTTPVRMSVPI 406
            +   +   RMS+ +
Sbjct: 3674 ISTFSRVQRMSISV 3687



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 111/554 (20%), Positives = 202/554 (36%), Gaps = 110/554 (19%)

Query: 32   VIVSSPIPME-TELEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTT 90
            VI S PI +  TE   +  I  TG          P+   S  T  +   TT ++A +++ 
Sbjct: 6717 VIPSLPISLGITESSNMTIITRTGP---------PLGSTSQGTFTLDTPTTSSRAGTHSM 6767

Query: 91   VKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGS 150
                FP              S    ++NK     D ++ + T+ P  +K   ++     S
Sbjct: 6768 ATQEFPH-------------SEMTTVMNK-----DPEILSWTIPPSIEKTSFSS-SLMPS 6808

Query: 151  PIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLI 210
            P + + P S        TT +       P   +   T+G  PE       +  +   +++
Sbjct: 6809 PAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEIL 6868

Query: 211  NTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKA--------------- 255
             T    + ++     T   A    T +SG      + A    +KA               
Sbjct: 6869 TTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTV 6928

Query: 256  -----VTGQTTQVS-------PPVIAGRVLSQSTPGTPSKTITISE------SGVIGSTL 297
                 V+ +TT++         P +    +SQ+   +   +I +SE      + V  + +
Sbjct: 6929 STSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEV 6988

Query: 298  NSTTQT----PNKIAISP----------LKSPNKAVKSTVQTITVGGVSTSQFKTIIPLA 343
             S+ +T    P++  + P            SP     + +   T  G S S  +  + L 
Sbjct: 6989 TSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLD 7048

Query: 344  TAPNVQQIQVPGS---KFHYVRLVTATS---------ASSSTQPVSQNPSTNTQPLQQAK 391
            T+    Q +   +   +F +  + T  S         +S S +  S  PS  + P   + 
Sbjct: 7049 TSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSP 7108

Query: 392  PVVVNTTPVRMS---VPIVSAQAVKQVVPKPINPTS-QIVTTSQPQ------QRLI--MP 439
            P + +T PV +S   +P+ S      V    +  TS ++VT+S P+      +RL     
Sbjct: 7109 PPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKD 7168

Query: 440  ATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQ--------YVTQLQQSSYVSIAS 491
             T    + P+ TN     V  P+ G  +   A+  ++        ++T  Q+ + V+I S
Sbjct: 7169 TTNTEAVHPS-TNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAI-S 7226

Query: 492  NSTFTGTSGIQTQA 505
               F  TS IQ ++
Sbjct: 7227 TPHFLETSRIQKES 7240



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 64/278 (23%), Positives = 105/278 (37%), Gaps = 28/278 (10%)

Query: 236  PTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGS 295
            PT+ P++    F +  ++ ++  +TT  +  ++  R     T   PS +   S S +I +
Sbjct: 2324 PTTSPIVLTASFTET-STVSLDNETTVKTSDILDAR----KTNELPSDSS--SSSDLINT 2376

Query: 296  TLNSTTQTPNKIA-ISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVP 354
            ++ S+T    K A ISP         S+    +          T    AT+P+V      
Sbjct: 2377 SIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVS----- 2431

Query: 355  GSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQ 414
             S  + +   +    + ST P    P T T P++ +  ++  + PVR    +VS      
Sbjct: 2432 -SNTYSLDGGSNVGGTPSTLP----PFTITHPVETSSALLAWSRPVRTFSTMVSTDTASG 2486

Query: 415  VVPKPINPT-SQIVTTSQPQQ---RLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGY 470
                  NPT S  V TS P       +   T LP +   L   P G   +    T     
Sbjct: 2487 E-----NPTSSNSVVTSVPAPGTWTSVGSTTDLPAM-GFLKTSPAGEAHSLLASTIEPAT 2540

Query: 471  AVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLP 508
            A  P      +  SS  S AS  T + +  I +  + P
Sbjct: 2541 AFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTP 2578



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 86/462 (18%), Positives = 161/462 (34%), Gaps = 54/462 (11%)

Query: 42   TELEEIVNINSTGDSTATP--ISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGL 99
            T + EI     T   +  P  I  +P +  S     V+ +++ +KA ++ T  P      
Sbjct: 2827 TAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAP------ 2880

Query: 100  QKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKL-ILTTLGKSGSPIVLALPH 158
                   P        +  + S+   L   + +L   GQ L  +     S +   L+   
Sbjct: 2881 -------PTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSP 2933

Query: 159  SQLPQAQKVTTQA--------QSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLI 210
             + P+A+ +T+           +G  + P         G  P V P  G       S+ +
Sbjct: 2934 EKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRV-PTSGTGDPRYASESM 2992

Query: 211  NTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAG 270
            +    PS   +    T   +K     ++G        + PI S +   +T+ +SP     
Sbjct: 2993 SYP-DPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPI-SLSTEKETSFLSPTASTS 3050

Query: 271  R----VLSQSTPGTPSKTITISESGVI---GSTLNSTTQTPNKIAISPLKSPNKAVKSTV 323
            R     L  S    P+  + +  S +     STLN + + P ++  S   +  +   +  
Sbjct: 3051 RKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAET 3110

Query: 324  QTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSST---------- 373
            QT+T     T      +   T P  ++   P +    + +   TS   +T          
Sbjct: 3111 QTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKM 3170

Query: 374  -QPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQP 432
                +Q  ST   P ++       T+P   S  + +   +       I+P  +    + P
Sbjct: 3171 SSQAAQGNSTWPAPAEETGSSPAGTSP--GSPEMSTTLKIMSSKEPSISPEIRSTVRNSP 3228

Query: 433  QQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLP 474
             +    P T +P      T + P T+ + A G+G+   + LP
Sbjct: 3229 WK---TPETTVPM----ETTVEPVTLQSTALGSGSTSISHLP 3263


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 71/300 (23%), Positives = 111/300 (37%), Gaps = 53/300 (17%)

Query: 199 GVSALTPGS-QLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVT 257
           G  AL PGS  L+     P+VL  Q L   Q            V+ K +  +P       
Sbjct: 155 GPQALFPGSTDLLGLQGPPTVLTHQALVPPQ-----------DVVNKALSVQPFLQPVGL 203

Query: 258 GQTTQVSPPVIAGRVLSQSTPG-TPSKTITISESGVIGS---TLNSTT------QTPNKI 307
           G  T    P + G  L   +PG   + T+ ++   V+G     LN+ T      Q P   
Sbjct: 204 GNVTLQPIPGLQG--LPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSG 261

Query: 308 AISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTAT 367
            ++    P++ V     T+   GVS      +I    +  V       S F      +A 
Sbjct: 262 YLASAAGPSEPV-----TLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAP 316

Query: 368 SASSSTQPVSQNPSTNTQPLQQAKPVVVN--TTPVRMSVPIVSAQAVKQVVPKPINPTSQ 425
           + + S QP++  P   + PL  A  V+++   TP++     V    + Q+ PKP  P   
Sbjct: 317 TGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGA 376

Query: 426 IVT--------TSQPQ--------------QRLIMPATPLPQIQPNLTNLPPGTVLAPAP 463
            +T          QP+              Q +++   P P +Q N+   PP T    AP
Sbjct: 377 TLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAP 436



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 82/341 (24%), Positives = 115/341 (33%), Gaps = 67/341 (19%)

Query: 138 QKLILTTLGKSGSPIVL------ALPHSQLPQAQKVTTQA---QSGDAKLPPQQIKVVTI 188
           Q L     GK+G  +VL      AL  +   Q    TT A   Q   A   P  + ++  
Sbjct: 395 QNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQ 454

Query: 189 GGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTV------QIAKKPRTPTSGPVI 242
           G       VI    + PG         P+V   QQL  +      QI       T G +I
Sbjct: 455 GS----SIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLI 510

Query: 243 TKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQ 302
                A PI    +T Q   ++ P+  G VL+   P + + +  I  +  I     +  Q
Sbjct: 511 -----ANPI----LTNQN--LAGPLSLGPVLA---PHSGAHSAHILSAAPIQVGQPALFQ 556

Query: 303 TPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVR 362
            P  +A   L + ++   +     TV      Q  T+ P A A     +  P      V+
Sbjct: 557 MPVSLAAGSLPTQSQPAPAGPAATTV-----LQGVTLPPSAVA----MLNTPDG---LVQ 604

Query: 363 LVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINP 422
             T  +A+    PV        QP  QA P V    P+ +  P        Q    P  P
Sbjct: 605 PATPAAATGEAAPV-----LTVQPAPQAPPAVSTPLPLGLQQP--------QAQQPPQAP 651

Query: 423 TSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAP 463
           T Q             P    PQ  P L + P   VL   P
Sbjct: 652 TPQAAAP---------PQATTPQPSPGLASSPEKIVLGQPP 683


>gi|148612838 hypothetical protein LOC158358 [Homo sapiens]
          Length = 2103

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 100/440 (22%), Positives = 166/440 (37%), Gaps = 70/440 (15%)

Query: 46   EIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQ 105
            +  NINS   S A+     P TV +   N  A N TIT   + ++ +P   S +  +   
Sbjct: 1141 QTTNINS---SLASVFVNSPGTVSTQLPN-TAFNKTITPLSNISSARPQPLSPVTSVSNL 1196

Query: 106  TPVTISANQIILNKVSQ-----TSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQ 160
               ++  +Q    K        T  L   + T+   GQ L  TT           L  S 
Sbjct: 1197 LTPSVKTSQSEAGKAKNAVSAATFSLPSASPTISSTGQPLSSTT----------TLNGST 1246

Query: 161  LPQAQKVTTQAQSGDAKLPPQQIKVVTI-----------GGRPEVKPVIGVSALTPGSQL 209
             P +       Q+ D+    Q++K V I           GG   V  V       P    
Sbjct: 1247 NPGSSFNCFAQQTADSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKV----QTNPDQNS 1302

Query: 210  INTTTQPSVLQ-TQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQT-TQVSPPV 267
             NT +  SV     QL+   +   P++ TS    + +      +S +   QT T VS P 
Sbjct: 1303 PNTVSSSSVFTFAPQLQAFLV---PKSTTSSSAFSPVAGTTTTSSLSPFSQTPTSVSIPA 1359

Query: 268  IAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTIT 327
                 + ++   T   T   + SG +G  ++ T+  P+    S + S      +T  +++
Sbjct: 1360 SFAPSMGKNLKLTLGHT---TGSGDLGHVIDKTSHMPSSPLKSSICSSTLLPSTTSSSVS 1416

Query: 328  VGGVSTSQF--KTIIPLATAPNVQQIQ---------------------VPGSKFHYVRLV 364
            V  +S + F       + T    QQ+                      + G+    + LV
Sbjct: 1417 VISISAANFGQNNANIIHTPTKQQQVDYITKSYPVTRSEATAATNGDVISGTPVQKLMLV 1476

Query: 365  TATSASSSTQ--PVSQNPSTNTQPLQQAKPVVVNT-TPVRMSVPIVSAQAVKQVVPKPIN 421
            +A S  SS     ++  P+  +  +   K V +N   P   S P + A+++KQ +P P++
Sbjct: 1477 SAPSILSSGNGTAINMTPALTSTGVSAQKLVFINAPVPSGTSTPTLVAESLKQTLPPPLH 1536

Query: 422  PTSQIVTTSQPQQRLIMPAT 441
              + + T  QPQ  LI P+T
Sbjct: 1537 -KAYVKTPEQPQIVLI-PST 1554


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 91/381 (23%), Positives = 135/381 (35%), Gaps = 58/381 (15%)

Query: 157  PHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQ--LINTTT 214
            P   LPQ Q   +Q  +G   + PQ         +P   P     A+T G    ++  T 
Sbjct: 2520 PPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTI 2579

Query: 215  QPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTT--QVSPPVIAGRV 272
            + SV  T           P    SG VI   I   P    A T Q+   +++ PV  G +
Sbjct: 2580 KTSVTGTSM---------PTGAVSGNVIVNTIAGVP----AATFQSINKRLASPVAPGAL 2626

Query: 273  LSQSTPG--TPSKTI-TISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVG 329
               +TPG   P++ + T      +GS   +T    +      +++      S V T  + 
Sbjct: 2627 ---TTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLT 2683

Query: 330  GVSTSQFKTIIPLATAPNVQQIQVPGSKF---HYVRLVTATSASSSTQPVSQNPSTNTQP 386
             V T     +  ++ A  VQ   +PG      H+  L          Q   Q      Q 
Sbjct: 2684 PVQTPARSLVPQVSQATGVQ---LPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQ 2740

Query: 387  LQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLP-- 444
             QQ +     T+ V+  VP +  QA      K +   +        +Q+L MP  P P  
Sbjct: 2741 QQQQQQQTTTTSQVQ--VPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQ 2798

Query: 445  ----------QIQPNLTNLPP-------GTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYV 487
                      Q+Q   T+ PP        TV AP PG      A+L    V  LQ +   
Sbjct: 2799 AQSAPPQPTAQVQVQ-TSQPPQQQSPQLTTVTAPRPG------ALLTGTTVANLQVARLT 2851

Query: 488  SIASNSTFTGTSGIQTQARLP 508
             + + S       +QTQA  P
Sbjct: 2852 RVPT-SQLQAQGQMQTQAPQP 2871



 Score = 36.6 bits (83), Expect = 0.088
 Identities = 65/280 (23%), Positives = 100/280 (35%), Gaps = 29/280 (10%)

Query: 165 QKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQL 224
           Q V  Q    DA +P QQ+     GG P       ++      Q  + +T P V     L
Sbjct: 490 QGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASL 549

Query: 225 KTVQIAKKPRTPTSGPVITKLIFAKPI-NSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSK 283
            T       R P +G     L  A        V    TQ+  PV   +  +   P  PS 
Sbjct: 550 HTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQP-NVPIPAPPSS 608

Query: 284 TITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLA 343
            + I  S      L+  T    ++  S L S  + V S                T +P+ 
Sbjct: 609 QLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVAS----------------TRLPVD 652

Query: 344 TAPNVQQIQVPGSKFHYVRLVTATSASSS---TQPVSQNPSTNT----QPLQQAKPVVVN 396
            AP   +  +P S    +  V+ +    S   + PV++ PS+ T     P+    P VV 
Sbjct: 653 PAPPCPR-PLPTSSTSSLAPVSGSGPGPSPARSSPVNR-PSSATNKALSPVTSRTPGVVA 710

Query: 397 TTPVRMSVPIVSAQAVKQVVPKPINPTSQIVTTSQPQQRL 436
           + P +   P  +A + +      +  T QI   +Q  QR+
Sbjct: 711 SAPTKPQSPAQNATSSQDSSQDTL--TEQITLENQVHQRI 748



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 63/293 (21%), Positives = 106/293 (36%), Gaps = 35/293 (11%)

Query: 194 VKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINS 253
           V PV+G      G+Q I  T  P  L +      Q + +PR    G   + +    P++ 
Sbjct: 79  VGPVVG------GNQQI--TLAPLPLPSPTSPGFQFSAQPRRFEHGSP-SYIQVTSPLSQ 129

Query: 254 KAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLK 313
           +  T   TQ SP    G+ L     G P   + +  S   G  ++++     +I++SP  
Sbjct: 130 QVQTQSPTQPSPG--PGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLV-RQISLSPSS 186

Query: 314 SPNKAVK--STVQTITVGG-VSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSAS 370
             +   +  S +  I  G  V      T I +      Q     G   H++   +  +A 
Sbjct: 187 GGHFVFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQSPAAAG 246

Query: 371 SSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQV-------VPKPIN-- 421
            +            QPL     +     P ++S  I+  Q V+Q        +P+P+   
Sbjct: 247 GA----------GLQPLASPSHITTANLPPQIS-SIIQGQLVQQQQVLQGPPLPRPLGFE 295

Query: 422 PTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLP 474
            T  ++             +P P   P+ T +PPG    P    GN G   +P
Sbjct: 296 RTPGVLLPGAGGAAGFGMTSPPPPTSPSRTAVPPGLSSLPLTSVGNTGMKKVP 348



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 39/158 (24%), Positives = 54/158 (34%), Gaps = 24/158 (15%)

Query: 359  HYVRLVTATSASSSTQ-PVSQNPSTNT---QPLQQAKPVVVNTTPVRMSVPIVSAQAVKQ 414
            H  R    T+AS++ Q P+   P   T    P  +A      T+    S P     +   
Sbjct: 1447 HPPRTAAPTTASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASS 1506

Query: 415  VVPKPINPTS-QIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYA-- 471
                P +P   +  TT+Q       P  P PQ Q            AP+   G       
Sbjct: 1507 TAASPAHPAKLRAQTTAQAST----PGQPPPQPQ------------APSHAAGQSALPQR 1550

Query: 472  -VLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLP 508
             VLP+Q   +L     V IA  ++ TG      Q   P
Sbjct: 1551 LVLPSQAQARLPSGEVVKIAQLASITGPQSRVAQPETP 1588


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 75/304 (24%), Positives = 111/304 (36%), Gaps = 38/304 (12%)

Query: 178 LPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPR--- 234
           L P     +T    P + P      LTP SQ I T +    L      T+  +  P    
Sbjct: 2   LTPSNTPTLTPSSPPTLTPS-STPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 60

Query: 235 ----------TPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPG----- 279
                     TPT  P  T  +  +PI +++ T   T  SPP +        TP      
Sbjct: 61  SNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTL 120

Query: 280 TPSKTITISESGVIGSTLNST-TQTPNKIAISPLKSPNKAVKSTVQTITVGGVST---SQ 335
           TPS T T++ S     T +ST T TP+   I    S      S+   +T     T   S 
Sbjct: 121 TPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSS 180

Query: 336 FKTIIPLAT---APNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKP 392
             T+ P +T    P+      P S+    R  T T   SS +P+   PS+       ++P
Sbjct: 181 TPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSS-RPI-LTPSSTPTLTPSSRP 238

Query: 393 VVVNTTPVRMSVPIVSAQAVKQVVPK---PINPTSQIVTTSQPQQRLIMPATP--LPQIQ 447
           ++      R S P ++  +   + P     + P++    T      L   +TP   P   
Sbjct: 239 IL-----TRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSST 293

Query: 448 PNLT 451
           P LT
Sbjct: 294 PTLT 297



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 75/313 (23%), Positives = 110/313 (35%), Gaps = 42/313 (13%)

Query: 83  TKADSNT-TVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLI 141
           T   SNT T+ P+ P  L    + TP    ++Q IL + S  +       TL P     +
Sbjct: 1   TLTPSNTPTLTPSSPPTLTP--SSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTL 58

Query: 142 LT----TLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPV 197
                 TL  S +P    L  S  P         +S    L P     +T    P + P 
Sbjct: 59  TPSNTPTLTPSSTP---TLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 115

Query: 198 IGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKP---------RTPTSGPVITKLIFA 248
                LTP +    T +    L      T+  + +P          TP+S P++T+   +
Sbjct: 116 -NTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTR--SS 172

Query: 249 KPINSKAVTGQTTQVSPPVIAGRVLSQSTPG-----TPSKTITISESGVIGSTLNST-TQ 302
            P  + + T   T  S P +        TP      T S T T++ S     T +ST T 
Sbjct: 173 TPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTL 232

Query: 303 TPNKIAISPLKSPNKAVKSTVQTITVGGVST-----------SQFKTIIPLAT---APNV 348
           TP+   I    S      S+  T+T     T           S   T+ P +T    P+ 
Sbjct: 233 TPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSS 292

Query: 349 QQIQVPGSKFHYV 361
                P S +H V
Sbjct: 293 TPTLTPSSLWHQV 305


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 75/304 (24%), Positives = 111/304 (36%), Gaps = 38/304 (12%)

Query: 178 LPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPR--- 234
           L P     +T    P + P      LTP SQ I T +    L      T+  +  P    
Sbjct: 2   LTPSNTPTLTPSSPPTLTPS-STPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 60

Query: 235 ----------TPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPG----- 279
                     TPT  P  T  +  +PI +++ T   T  SPP +        TP      
Sbjct: 61  SNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTL 120

Query: 280 TPSKTITISESGVIGSTLNST-TQTPNKIAISPLKSPNKAVKSTVQTITVGGVST---SQ 335
           TPS T T++ S     T +ST T TP+   I    S      S+   +T     T   S 
Sbjct: 121 TPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSS 180

Query: 336 FKTIIPLAT---APNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKP 392
             T+ P +T    P+      P S+    R  T T   SS +P+   PS+       ++P
Sbjct: 181 TPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSS-RPI-LTPSSTPTLTPSSRP 238

Query: 393 VVVNTTPVRMSVPIVSAQAVKQVVPK---PINPTSQIVTTSQPQQRLIMPATP--LPQIQ 447
           ++      R S P ++  +   + P     + P++    T      L   +TP   P   
Sbjct: 239 IL-----TRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSST 293

Query: 448 PNLT 451
           P LT
Sbjct: 294 PTLT 297



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 75/313 (23%), Positives = 110/313 (35%), Gaps = 42/313 (13%)

Query: 83  TKADSNT-TVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLI 141
           T   SNT T+ P+ P  L    + TP    ++Q IL + S  +       TL P     +
Sbjct: 1   TLTPSNTPTLTPSSPPTLTP--SSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTL 58

Query: 142 LT----TLGKSGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPV 197
                 TL  S +P    L  S  P         +S    L P     +T    P + P 
Sbjct: 59  TPSNTPTLTPSSTP---TLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 115

Query: 198 IGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKP---------RTPTSGPVITKLIFA 248
                LTP +    T +    L      T+  + +P          TP+S P++T+   +
Sbjct: 116 -NTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTR--SS 172

Query: 249 KPINSKAVTGQTTQVSPPVIAGRVLSQSTPG-----TPSKTITISESGVIGSTLNST-TQ 302
            P  + + T   T  S P +        TP      T S T T++ S     T +ST T 
Sbjct: 173 TPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTL 232

Query: 303 TPNKIAISPLKSPNKAVKSTVQTITVGGVST-----------SQFKTIIPLAT---APNV 348
           TP+   I    S      S+  T+T     T           S   T+ P +T    P+ 
Sbjct: 233 TPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSS 292

Query: 349 QQIQVPGSKFHYV 361
                P S +H V
Sbjct: 293 TPTLTPSSLWHQV 305


>gi|239749213 PREDICTED: mucin 3B, cell surface associated, partial
           [Homo sapiens]
          Length = 1063

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 114/520 (21%), Positives = 191/520 (36%), Gaps = 112/520 (21%)

Query: 44  LEEIVNINSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQ--- 100
           +  I+   +T  ST +  S+   +  S+ T   A+ +  T A++  T  P+ PS L    
Sbjct: 166 MSSIITTETTSHSTPSFTSSTIHSTVSSSTT--AITSPFTTAETGVTSTPSSPSSLSTDI 223

Query: 101 ---KLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALP 157
               L   TP+++S +      ++ T+DL              I T +    +PI +   
Sbjct: 224 PTTSLRTLTPLSLSTS----TSLTTTTDL------------PSIPTDISSLPTPIHII-- 265

Query: 158 HSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPS 217
            S  P  Q   T +  G                 P +  V      T  + + + +T   
Sbjct: 266 -SSSPSIQSTETSSLVGTTS--------------PTMSTVRATLRSTENTPISSFST--- 307

Query: 218 VLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQS- 276
                      I   P TPT+         A P+   A   QT+ V   V  G + S + 
Sbjct: 308 ----------SIVVTPETPTTQ--------APPVLMSATGTQTSPVPTTVTFGSMDSSTS 349

Query: 277 -----TPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
                TP T    I  +    I ST +ST QT   I  S   S     + T ++ T G  
Sbjct: 350 TLHTLTPSTALSKIMSTSQFPIPSTHSSTLQTTPSIP-SLQTSLTSTSEFTTESFTRGST 408

Query: 332 ST----SQFKTI-------IPLATAPNVQQI---------QVPGSKFHYVRLVTATSASS 371
           ST    + F TI       I ++++P+   I          VP S + +      +++ +
Sbjct: 409 STNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFATTIHSVPSSPYIFSTENVGSASIT 468

Query: 372 STQPVSQNPSTNTQPLQQA-KPVVVNTTPVR-MSVPIVS-AQAVKQVVPKPINPTSQIVT 428
           +   +S + +T+T P   +    +   TP   +S+P  +       +   P +PT   V 
Sbjct: 469 AFPSLSSSSTTSTSPTSSSLTTALTEITPFSYISLPSTTPCPGTITITIVPASPTDPCVE 528

Query: 429 TSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAV---LPAQYVTQLQQSS 485
                +    P TP       LT  P  T +   P + ++   +   +    +T   +SS
Sbjct: 529 MDPSTEATSPPTTP-------LTVFPFTTEMVTCPSSISMQTTLATHMDTSSMTPESESS 581

Query: 486 YVSIASNSTFTG---TSGIQTQARLPF-------NGIIPS 515
            +  AS+ST TG   T+ + T  RLP        N +IP+
Sbjct: 582 IIPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNNSVIPT 621



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 80/348 (22%), Positives = 124/348 (35%), Gaps = 74/348 (21%)

Query: 213 TTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPP----VI 268
           TT  +   +    T  I K   T  S P  T        +S ++T   +  +PP    V 
Sbjct: 102 TTNETTSHSTPSFTTSITKTKTTSHSTPSFT--------SSNSITDSRSHSTPPFTSSVT 153

Query: 269 AGRVLSQSTPGTPSKTITI-----SESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKST- 322
              + S +TP   S  IT      S      ST++ST  +      SP  +    V ST 
Sbjct: 154 TPEMTSHNTPSFMSSIITTETTSHSTPSFTSSTIHSTVSSSTTAITSPFTTAETGVTSTP 213

Query: 323 --------------VQTITVGGVSTSQFKTI------IP------------LATAPNVQQ 350
                         ++T+T   +STS   T       IP            ++++P++Q 
Sbjct: 214 SSPSSLSTDIPTTSLRTLTPLSLSTSTSLTTTTDLPSIPTDISSLPTPIHIISSSPSIQS 273

Query: 351 IQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNT-TPVRMSVPIVSA 409
            +          LV  TS + ST   +   + NT     +  +VV   TP   + P++ +
Sbjct: 274 TETSS-------LVGTTSPTMSTVRATLRSTENTPISSFSTSIVVTPETPTTQAPPVLMS 326

Query: 410 QAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVG 469
               Q  P P   T   + +S      + P+T L +I          T   P P T +  
Sbjct: 327 ATGTQTSPVPTTVTFGSMDSSTSTLHTLTPSTALSKIM--------STSQFPIPSTHSST 378

Query: 470 YAVLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSES 517
               P+  +  LQ     S+ S S FT  S   T+     N I+ S S
Sbjct: 379 LQTTPS--IPSLQ----TSLTSTSEFTTES--FTRGSTSTNAILTSFS 418


>gi|169217460 PREDICTED: similar to Mucin-6, partial [Homo sapiens]
          Length = 350

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 60/263 (22%), Positives = 96/263 (36%), Gaps = 7/263 (2%)

Query: 238 SGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTIT-ISESGVIGST 296
           S P  T      P ++  VT  T  V  P  A    S S   TP+ TI  ++     GST
Sbjct: 13  SHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSTPTGTIPPLTTLMNTGST 72

Query: 297 LNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGS 356
             +   TP     S   S     K++  T      S++    + P AT          GS
Sbjct: 73  HTAPPVTPTTSGTSQAASSFSTAKTS--TSLHSHTSSTHHPEVTPTATTKITTNPTSIGS 130

Query: 357 KFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVV 416
                   +ATS+  +T   + +PST + P+    P+   +     + P  S    +  +
Sbjct: 131 STPMAHTTSATSSRLTTPFTTHSPSTGSSPVSSTGPMTATSFQTTTTYPTPSLS--QTTL 188

Query: 417 PKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQ 476
           P  + P S  + T      +  P T +     ++ + P GT+  P            P +
Sbjct: 189 PTYVPPFSTSLVTPSTHTVITPPRTQM-ATSASIHSTPTGTIPPPTTLKATGSTHTAPTR 247

Query: 477 YVTQLQQSSYVSIASNSTFTGTS 499
            +T    S  +S + N+  T TS
Sbjct: 248 TLTTSGTSQALS-SLNTAKTSTS 269



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 71/342 (20%), Positives = 119/342 (34%), Gaps = 47/342 (13%)

Query: 67  TVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDL 126
           +++S  T  +   TT+    S  T  P            TP T   +Q   +  +  +  
Sbjct: 51  SIHSTPTGTIPPLTTLMNTGSTHTAPPV-----------TPTTSGTSQAASSFSTAKTST 99

Query: 127 KLGNQTLKPDGQKLILTTLGK-SGSPIVLALPHSQLPQAQKVTTQAQSGDAKLPPQQIKV 185
            L + T      ++  T   K + +P  +    S  P A   TT A S     P      
Sbjct: 100 SLHSHTSSTHHPEVTPTATTKITTNPTSIG---SSTPMAH--TTSATSSRLTTP-----F 149

Query: 186 VTIGGRPEVKPVIGVSALTPGS-QLINTTTQPSVLQTQQLKTVQ-IAKKPRTPTSGPVIT 243
            T        PV     +T  S Q   T   PS+ QT     V   +    TP++  VIT
Sbjct: 150 TTHSPSTGSSPVSSTGPMTATSFQTTTTYPTPSLSQTTLPTYVPPFSTSLVTPSTHTVIT 209

Query: 244 KLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQT 303
                   ++   +  T  + PP       + ST   P++T+T S +    S+LN+   +
Sbjct: 210 PPRTQMATSASIHSTPTGTIPPPTTLKA--TGSTHTAPTRTLTTSGTSQALSSLNTAKTS 267

Query: 304 PNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSKFHYVRL 363
            +  + +      +A  ++   IT    ST    T  P+A                    
Sbjct: 268 TSLHSHTSSTHHPEATSTSTTNITPNPTSTG---TGTPVA------------------HT 306

Query: 364 VTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVP 405
            +ATS+  +T   + +P T + P+    PV   +     + P
Sbjct: 307 TSATSSRLTTPFTTHSPPTGSTPISSTGPVTATSFHATTTYP 348


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 30/228 (13%)

Query: 239 GPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLS-QSTPGTPSKTITISESGVIGSTL 297
           GP  T L+ AK   S A+      + P  + G   + +     PS+ IT ++   I  +L
Sbjct: 316 GPAQTPLLPAKLSASNALD----PMLPASVGGSTRTPRPAAAQPSQKITATK---IPKSL 368

Query: 298 NSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGSK 357
            +    P+  +I P+KSP+   K+   + T   + T                Q QVP + 
Sbjct: 369 PTKPSAPST-SIVPIKSPHPTQKTAPSSFTKSALPT----------------QKQVPPTS 411

Query: 358 FHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVP 417
               R V A  +  + +P+ +NP     P    +P+   T+  +  +P ++    K +  
Sbjct: 412 ----RPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAK-ITS 466

Query: 418 KPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGT 465
               P S   +T +P     + ++P P      +  PP T++ P  GT
Sbjct: 467 HASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGT 514


>gi|148792970 TAF4b RNA polymerase II, TATA box binding protein
           (TBP)-associated factor, 105kDa [Homo sapiens]
          Length = 862

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 84/407 (20%), Positives = 154/407 (37%), Gaps = 59/407 (14%)

Query: 50  INSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQK-----LGA 104
           ++++G  T  P    P+ V S     VA+   +TKA  +  V+P     L+      +  
Sbjct: 17  VSASGTVTMAPAGALPVRVEST---PVALGA-VTKAPVSVCVEPTASQPLRSPVGTLVTK 72

Query: 105 QTPVT----------ISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVL 154
             PV+          + A QI+  K   T+ ++       P G  LI +  G    P++L
Sbjct: 73  VAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSG----PLML 128

Query: 155 ALPHSQLPQAQKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQL--INT 212
             P   + +A+  +           PQ +K+ T+        +I   A+TP  +L  I T
Sbjct: 129 VSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPN--SSSQLIKKVAVTPVKKLAQIGT 186

Query: 213 TTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRV 272
           T   +V +   +++V +      PTS   +T     KP+N+       T + P  +    
Sbjct: 187 TVVTTVPKPSSVQSVAV------PTSVVTVTP---GKPLNT------VTTLKPSSLGASS 231

Query: 273 LSQSTPGTPSKTITISESGVIGSTLNSTTQTPN------KIAISPLKSP--NKAVKSTVQ 324
              + P   ++     +  +  + L +  +  N      K+A S  +SP   + VK  V+
Sbjct: 232 TPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVE 291

Query: 325 TITVGGVSTSQF--KTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPS- 381
            +    +   +F  K  + L ++P    +         +R +   S S   Q V Q  S 
Sbjct: 292 QLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSD 351

Query: 382 ------TNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINP 422
                 T T          V+++    S+ +  A A + V  + +NP
Sbjct: 352 MVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNP 398



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 63/260 (24%), Positives = 99/260 (38%), Gaps = 44/260 (16%)

Query: 73  TNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQT------PVTISANQIILNKVSQTS-- 124
           T    V TT++ + S  ++  +  +  + +  QT      PV   A  + L+ V  T+  
Sbjct: 362 TTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAAT 421

Query: 125 -DLKLGN---QTLKPDGQKLI--LTTLGK-------SGSPIVLALPHSQLPQAQKVTTQA 171
                G    QT KP    +   +TT+         SG+ + L+LP         VT   
Sbjct: 422 GGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLP--------AVTFGE 473

Query: 172 QSGDAKLPPQQIKVVTIGGRPEVKPVIG----VSALTPGSQLINTTTQPSVLQTQQLKTV 227
            SG A   P    VV+  G    KPVIG    +    PG  L      P  +Q +QL   
Sbjct: 474 TSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQ 533

Query: 228 QIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITI 287
           Q       P+ G    K +     +S     +  Q + PV      SQ  P +  K IT+
Sbjct: 534 Q-------PSGGN--EKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITL 584

Query: 288 SESGVIGSTLNSTTQTPNKI 307
             + ++  +L ++    N+I
Sbjct: 585 PGNKIL--SLQASPTQKNRI 602


>gi|24429588 zinc finger protein 532 [Homo sapiens]
          Length = 1301

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 82/421 (19%), Positives = 153/421 (36%), Gaps = 59/421 (14%)

Query: 51  NSTGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTI 110
           N T   +  P  T+  +  S+    +A   +  KA S++  +P   S   +  +  P  +
Sbjct: 249 NDTSLPSVAPSKTKSSSKLSSCIAAIAA-LSAKKAASDSCKEPVANS---RESSPLPKEV 304

Query: 111 SANQIILNKVSQTSDLKLGNQ--TLK-PDGQKLILTTLGKSGSPIVLALPHSQLPQAQKV 167
           + +    +K  ++ +L  G +  +LK PD  + I +     GSP   A     +P+ +  
Sbjct: 305 NDSPRAADKSPESQNLIDGTKKPSLKQPDSPRSISSENSSKGSPSSPAGSTPAIPKVRIK 364

Query: 168 TTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGV-SALTPGSQLINTTTQPSVLQTQQLKT 226
           T +  SG+ K      + VT      V P + + S   P  Q  +     + L +     
Sbjct: 365 TIKTSSGEIK------RTVT-----RVLPEVDLDSGKKPSEQTASVMASVTSLLSSPASA 413

Query: 227 VQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTIT 286
             ++  PR P    V+T  +    +  K VT              +   +T   P   + 
Sbjct: 414 AVLSSPPRAPLQSAVVTNAVSPAELTPKQVT--------------IKPVATAFLPVSAVK 459

Query: 287 ISESGVIGSTL-NSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATA 345
            + S VI   L N+TT     I+ + ++S + A+      I        Q   ++P ++ 
Sbjct: 460 TAGSQVINLKLANNTTVKATVISAASVQSASSAIIKAANAI-------QQQTVVVPASSL 512

Query: 346 PNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVP 405
            N + +         V L          Q  S+     T+P QQ K  ++N    +    
Sbjct: 513 ANAKLVP------KTVHLANLNLLPQGAQATSELRQVLTKPQQQIKQAIINAAASQPPKK 566

Query: 406 IVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGT 465
           +   Q V  +    +   ++++++            P+P   PNL+  PP       P  
Sbjct: 567 VSRVQVVSSLQSSVVEAFNKVLSS----------VNPVPVYIPNLS--PPANAGITLPTR 614

Query: 466 G 466
           G
Sbjct: 615 G 615


>gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo
           sapiens]
          Length = 514

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 95/509 (18%), Positives = 181/509 (35%), Gaps = 78/509 (15%)

Query: 27  DSIEAVIVSSPIPMETELEEIVNINSTGDSTATPI-STEPITVYSNHTNQVAVNTTITKA 85
           D+ +    SS       +    N N + +S  TP+ ST PIT     TN V   TT+T  
Sbjct: 12  DTGQTTFTSSTATFPETITLTPNTNMSRESLMTPMTSTTPITSAITPTNTVTSMTTMTSP 71

Query: 86  DSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTL 145
            + T       S    + + T V  S + I     S T++L   +  L       + TT+
Sbjct: 72  PTTTNSNSTLSSLTSSILSSTLVP-STDMI----TSHTTNLTRSSPLL-----ATLPTTI 121

Query: 146 GKSGSPIVLALPHSQLPQAQKVTTQAQ---------SGDAKLPPQQIKVVTIGGRPEVKP 196
            +S        P S     +  TT  +         S +  LPP    + T         
Sbjct: 122 TRSTPTSETTYPTSPTSTVKGSTTSIRYSTSMTGTLSMETSLPPTSSSLPTT-------- 173

Query: 197 VIGVSALTPGSQLINTT---------TQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIF 247
               +A TP + L+ T          +  ++  T    T  I+  P  PTSG ++T +  
Sbjct: 174 ---ETATTPTTNLVTTEITSHSTPSFSSSTIHSTVSTPTTVISSGP--PTSGTIVTSI-- 226

Query: 248 AKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKI 307
                   VT  +     P+     ++  + G+    +T ++       L ST    +  
Sbjct: 227 -------TVTPSSLSTDIPLTTPTTITHHSVGSTESLLTATD-------LTSTFTVSSSS 272

Query: 308 AISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQ-----VPGSKFHYVR 362
           A+S    P+       +T ++  ++++   ++ P  T+ +           PG+      
Sbjct: 273 AMSTSDIPSSPSIQNTETSSLVSMTSATIPSVRPTFTSTHNTLTSSLLTTFPGTYSFSSS 332

Query: 363 LVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVVPKPINP 422
           +  ++  ++ T+ ++  P++ +     A+    +TT    +                 +P
Sbjct: 333 MSASSDGTTHTETITSLPASTSTLHTTAESTTAHTTTTSFTTSTTME-----------SP 381

Query: 423 TSQIVTTSQPQQRLIMPA---TPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVT 479
           +S + TTS  Q          T    + P  T+    T+      T  +  ++ P   VT
Sbjct: 382 SSSVATTSTGQTTFSSSTATFTETTTLTPT-TDFSEETLTTAMTSTPPITSSITPTNTVT 440

Query: 480 QLQQSSYVSIASNSTFTGTSGIQTQARLP 508
            +   +    A+N+  + T+ I +   +P
Sbjct: 441 SMTTMTSWPTATNTLSSLTTNILSSTPVP 469



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 68/287 (23%), Positives = 97/287 (33%), Gaps = 64/287 (22%)

Query: 241 VITKLIFAKPINS-----KAVTGQTTQVSPPVIAGRVLSQSTPGTPSKTITISESGVIGS 295
           ++T +    PI S       VT  TT  SPP       S ST    S T +I  S ++ S
Sbjct: 42  LMTPMTSTTPITSAITPTNTVTSMTTMTSPPTTTN---SNST--LSSLTSSILSSTLVPS 96

Query: 296 TLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPG 355
           T   T+ T N    SPL                             LAT P       P 
Sbjct: 97  TDMITSHTTNLTRSSPL-----------------------------LATLPTTITRSTPT 127

Query: 356 SKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQV 415
           S+  Y    T+T   S+T        T T  ++ + P      P   S+P          
Sbjct: 128 SETTYPTSPTSTVKGSTTSIRYSTSMTGTLSMETSLP------PTSSSLPTTETAT---- 177

Query: 416 VPKPINPTSQIVTTSQPQQRLIMPATP-LPQIQPNLTNLPPGTVLA---PAPGTGNVGYA 471
                 PT+ +VTT      +   +TP       + T   P TV++   P  GT      
Sbjct: 178 -----TPTTNLVTT-----EITSHSTPSFSSSTIHSTVSTPTTVISSGPPTSGTIVTSIT 227

Query: 472 VLPAQYVTQLQQSSYVSIASNSTFTGTSGIQTQARLPFNGIIPSESA 518
           V P+   T +  ++  +I  +S    T  + T   L     + S SA
Sbjct: 228 VTPSSLSTDIPLTTPTTITHHSV-GSTESLLTATDLTSTFTVSSSSA 273


>gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo
           sapiens]
          Length = 1064

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 96/457 (21%), Positives = 176/457 (38%), Gaps = 47/457 (10%)

Query: 57  TATPI-STEPITVYSNHTNQVA-----VNTTITKADSNTTVKPAFPSGLQKLGAQTPVTI 110
           ++TP+ STE  T ++  TN ++     + TTIT+  S  T +  +P+        +   I
Sbjct: 291 SSTPVPSTEMTTSHTTDTNPLSTLVTTLPTTITR--STPTSETTYPASPTSTVTDSTTEI 348

Query: 111 SANQIILNKVSQTSDL------KLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQA 164
           + + ++   +S T+ L      +   +T      KL+ TT  ++ S   L    S +   
Sbjct: 349 TYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPTTKLVTTTT-ETTSQSSLNFSSSAIYST 407

Query: 165 QKVTTQAQSGDAKLPPQQIKVVTIGGRPEVKPVIGVSALTPGSQLINTTTQPSVLQTQQL 224
              +T A S    LPP    +VT         ++  + L P  +LI        +Q +  
Sbjct: 408 VSTSTTAISS---LPPTSGTMVTSTN------IVPTADLKP--ELILLEVHDQRIQAKNP 456

Query: 225 KTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQVSPPVIAGRVLSQSTPGTPSKT 284
           +  Q      T TS P  T L     I+++++T   T  +P      V+S  TP T   T
Sbjct: 457 RYSQTPFTSSTATS-PETTTLTCTNDISTESLTTAMTSTTP------VISAITPKT---T 506

Query: 285 ITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGVSTSQFKTIIPLAT 344
           +T   +   G T  +T  +     +S   +PN  V ++  T T      S   T +P A 
Sbjct: 507 VTSMTTTASGPTTTNTLSSLTSSILSSTPAPNTEVITSHTTTT---TPPSTLVTTLPTAI 563

Query: 345 APNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSV 404
           A +      P S+  Y    T T   S T+       T T       P+   + P  +  
Sbjct: 564 ARS-----TPTSETTYPISPTGTVTDSMTEITYSTSMTGTWSTATTLPLTSCSLPT-IET 617

Query: 405 PIVSAQAVKQVVPKPINPTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPG 464
                  +     +  + ++   T+S     + +  T +    P+   +   T + P+  
Sbjct: 618 ATTPTTNLGNTTTETTSHSTPSFTSSAIYSTVNISTTTISSFPPSSGTMVTFTTMNPSSL 677

Query: 465 TGNVGYAVLPAQYVTQLQQSSYVSIASN--STFTGTS 499
           + ++    L       +  + +++ A++  STFT +S
Sbjct: 678 STDISTTTLKNITQPSVGSTGFLTAATDLTSTFTVSS 714



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 68/367 (18%), Positives = 138/367 (37%), Gaps = 53/367 (14%)

Query: 52   STGDSTATPISTEPITVYSNHTNQVAVNTTITKADSNTTVKPAFPSGLQKLGAQTPVTIS 111
            S+  + +T ++    ++ +   + +   TT T      T+     +    +   +PVT S
Sbjct: 713  SSSSAMSTSVTPSAPSIQNKEISTLVSTTTTTSPTERMTLTSTENTPTSYILTTSPVTYS 772

Query: 112  ANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQA-QKVTTQ 170
             +      +S +SD     +++              S +P + +  H+         TT 
Sbjct: 773  FSP----SMSASSDWTTDTESI--------------SSAPAITSTLHTTAESTLAPTTTN 814

Query: 171  AQSGDAKLPPQQIKVVTIGGRPE--------------VKPVIGVSALTPGSQLINTT--T 214
            + +  A + P    V T G                  + P   +S  +  + +I+TT  T
Sbjct: 815  SFTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTTLTPTTDISTESFMTPMISTTPIT 874

Query: 215  QPSVLQTQQLKTVQIAKKPRTP-TSGPVITKLIFAKPINS-KAVTGQTTQ-VSPPVIAGR 271
                L+         A +P T  T   + + ++ + P+ S + +T QTT   SP  +   
Sbjct: 875  SSMTLRNTMTSMTTAASRPTTTNTLSSLTSSILSSTPVPSTEVITSQTTNTTSPSTLVTT 934

Query: 272  VLSQSTPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKAVKSTVQTITVGGV 331
            + +  T  TP+   T S S    +  +STT+T    +I+   S   ++ +T  ++   G+
Sbjct: 935  LPTTITTSTPTSETTYSTSPT-STVTDSTTETTYSTSITGTLSTEISLPATTSSLITKGI 993

Query: 332  STSQFKTIIPLATAPNVQQIQVPGSKFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAK 391
            S +  + ++                      L   ++ S+ST  +S  P+T       + 
Sbjct: 994  SMTSTRNLVTTTNENTSHSTPT-------FTLTIHSTISTSTTAISSVPTT-------SG 1039

Query: 392  PVVVNTT 398
            P+V +TT
Sbjct: 1040 PIVTSTT 1046



 Score = 37.0 bits (84), Expect = 0.067
 Identities = 60/254 (23%), Positives = 94/254 (37%), Gaps = 44/254 (17%)

Query: 195 KPVIGVSALTPGSQLINTTT----QPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKP 250
           KPV  V+   P +     T+     PS    ++   V +     TP+S    T   F   
Sbjct: 161 KPVTTVTRTYPMTTTEKGTSAMISSPSTTTARETPIVTV-----TPSSSVSATDTTFHTT 215

Query: 251 INSKAVTGQTTQVSP-----------PVIAGRVLSQSTPGTPSKTITISESGVIGSTLNS 299
           I+S   T +TT+ +P           P      L  +   T   T TI+ +  + S   +
Sbjct: 216 ISS---TTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVTSTSPITSTITSTNTVTSMTTT 272

Query: 300 TTQTPNKIAISPLKS---PNKAVKSTVQTITVGGVSTSQFKTIIPLATAPNVQQIQVPGS 356
           T++      +S L S    +  V ST  T T     T+   T++   T P       P S
Sbjct: 273 TSRPTATNTLSSLMSNILSSTPVPSTEMT-TSHTTDTNPLSTLV--TTLPTTITRSTPTS 329

Query: 357 KFHYVRLVTATSASSSTQPVSQNPSTNTQPLQQAKPVVVNTTPVRMSVPIVSAQAVKQVV 416
           +  Y    T+T   S+T+       T T             +P     P  S+Q   Q  
Sbjct: 330 ETTYPASPTSTVTDSTTEITYSTVLTGT------------LSPTTTLPPTSSSQ---QTT 374

Query: 417 PKPINPTSQIVTTS 430
             P+ PT+++VTT+
Sbjct: 375 ETPMTPTTKLVTTT 388


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.126    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,114,138
Number of Sequences: 37866
Number of extensions: 1423015
Number of successful extensions: 6002
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 275
Number of HSP's that attempted gapping in prelim test: 4696
Number of HSP's gapped (non-prelim): 890
length of query: 749
length of database: 18,247,518
effective HSP length: 110
effective length of query: 639
effective length of database: 14,082,258
effective search space: 8998562862
effective search space used: 8998562862
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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