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Search of human proteins with 169218177
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169218177 PREDICTED: similar to fem-1 homolog a, partial
[Homo sapiens]
(287 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169218177 PREDICTED: similar to fem-1 homolog a, partial [Hom... 585 e-167
gi|24308163 fem-1 homolog a [Homo sapiens] 536 e-153
gi|17864094 feminization 1 homolog a [Homo sapiens] 363 e-101
gi|7657265 fem-1 homolog b [Homo sapiens] 131 6e-31
gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 50 3e-06
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 49 7e-06
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 49 7e-06
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 49 7e-06
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 49 7e-06
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 49 7e-06
gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo ... 48 9e-06
gi|89363047 death-associated protein kinase 1 [Homo sapiens] 47 1e-05
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 47 2e-05
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 47 2e-05
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 47 2e-05
gi|169403959 ankyrin repeat domain 53 isoform a [Homo sapiens] 46 3e-05
gi|169403957 ankyrin repeat domain 53 isoform b [Homo sapiens] 46 3e-05
gi|24233530 ankyrin repeat domain 44 [Homo sapiens] 46 4e-05
gi|68131557 ankyrin repeat domain 28 [Homo sapiens] 45 6e-05
gi|30348954 mindbomb homolog 1 [Homo sapiens] 45 1e-04
gi|10092619 nuclear factor of kappa light polypeptide gene enhan... 44 1e-04
gi|169203021 PREDICTED: similar to Shank2E [Homo sapiens] 44 1e-04
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1... 44 1e-04
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 44 2e-04
gi|71274109 nuclear factor of kappa light polypeptide gene enhan... 44 2e-04
gi|118150656 ankyrin repeat domain 7 [Homo sapiens] 43 3e-04
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 43 3e-04
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 43 3e-04
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ... 43 4e-04
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens] 43 4e-04
>gi|169218177 PREDICTED: similar to fem-1 homolog a, partial [Homo
sapiens]
Length = 287
Score = 585 bits (1508), Expect = e-167
Identities = 287/287 (100%), Positives = 287/287 (100%)
Query: 1 SPSHPDTSYCIRYRGAVYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELF 60
SPSHPDTSYCIRYRGAVYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELF
Sbjct: 1 SPSHPDTSYCIRYRGAVYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELF 60
Query: 61 SYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLL 120
SYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLL
Sbjct: 61 SYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLL 120
Query: 121 YLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLH 180
YLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLH
Sbjct: 121 YLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLH 180
Query: 181 VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYELLE 240
VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYELLE
Sbjct: 181 VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYELLE 240
Query: 241 EKLLARGTMQPFNYVTLQCLAAQALDKNKIPYKGFIPEDLEAFIELH 287
EKLLARGTMQPFNYVTLQCLAAQALDKNKIPYKGFIPEDLEAFIELH
Sbjct: 241 EKLLARGTMQPFNYVTLQCLAAQALDKNKIPYKGFIPEDLEAFIELH 287
>gi|24308163 fem-1 homolog a [Homo sapiens]
Length = 669
Score = 536 bits (1381), Expect = e-153
Identities = 267/286 (93%), Positives = 273/286 (95%)
Query: 2 PSHPDTSYCIRYRGAVYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFS 61
PSHPDTSY IRYRGAVYADSGN E IRLWKYALDMQQSNLEPL+PM+ASSFLSFAELFS
Sbjct: 384 PSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQSNLEPLSPMTASSFLSFAELFS 443
Query: 62 YVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLY 121
YVLQD AAKGSLGTQIGFADLMGVLTK VREVE ALQL REP DSAQF KALAIILHLLY
Sbjct: 444 YVLQDRAAKGSLGTQIGFADLMGVLTKGVREVERALQLPREPGDSAQFTKALAIILHLLY 503
Query: 122 LLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHV 181
LLEKVECTPSQEHLKHQT+YRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHV
Sbjct: 504 LLEKVECTPSQEHLKHQTVYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHV 563
Query: 182 VKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYELLEE 241
VKVL DCGAD DSRDFDNNTPLHIAAQNNCPAI+NAL EAGAHMDATNAFKKTAYELL+E
Sbjct: 564 VKVLLDCGADPDSRDFDNNTPLHIAAQNNCPAIMNALIEAGAHMDATNAFKKTAYELLDE 623
Query: 242 KLLARGTMQPFNYVTLQCLAAQALDKNKIPYKGFIPEDLEAFIELH 287
KLLARGTMQPFNYVTLQCLAA+ALDKNKIPYKGFIPEDLEAFIELH
Sbjct: 624 KLLARGTMQPFNYVTLQCLAARALDKNKIPYKGFIPEDLEAFIELH 669
>gi|17864094 feminization 1 homolog a [Homo sapiens]
Length = 617
Score = 363 bits (933), Expect = e-101
Identities = 183/286 (63%), Positives = 222/286 (77%), Gaps = 1/286 (0%)
Query: 2 PSHPDTSYCIRYRGAVYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFS 61
PSHPDTSY IRYRGAVYADSGN + I LWKYALDMQQSNL+PL+PM+ASS LSFAELFS
Sbjct: 332 PSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFS 391
Query: 62 YVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLY 121
++LQD AKG LGT + F DLMG+L K V E+E A++ + P D Q NKAL+IILHL+
Sbjct: 392 FMLQD-RAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNKALSIILHLIC 450
Query: 122 LLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHV 181
LLEKV CT Q+H K QTIYR LK PRGKN F+PLH+AVDK+TT VGRYPV +FPSL V
Sbjct: 451 LLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQV 510
Query: 182 VKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYELLEE 241
+L +CGAD + RD D+N+PLHIAA NN P I+N L ++GAH DATN K+TA +LL+E
Sbjct: 511 TAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDE 570
Query: 242 KLLARGTMQPFNYVTLQCLAAQALDKNKIPYKGFIPEDLEAFIELH 287
K +A+ +QP N+ TLQCLAA+ + ++I YKG IPE LE F+ LH
Sbjct: 571 KEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLH 616
>gi|7657265 fem-1 homolog b [Homo sapiens]
Length = 627
Score = 131 bits (330), Expect = 6e-31
Identities = 97/301 (32%), Positives = 152/301 (50%), Gaps = 34/301 (11%)
Query: 6 DTSYCIRYRGAVYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQ 65
D S+ I YRGAVYAD+ E I+LW +AL ++Q + L FA++FS ++
Sbjct: 342 DVSHPIIYRGAVYADNMEFEQCIKLWLHALHLRQKG----NRNTHKDLLRFAQVFSQMIH 397
Query: 66 DPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKA------LAIILHL 119
L + D+ VL V E+E ++ ++ D+ N L L+L
Sbjct: 398 -------LNETVKAPDIECVLRCSVLEIEQSMNRVKNISDADVHNAMDNYECNLYTFLYL 450
Query: 120 LYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDT--TNVGRYPVGRFP 177
+ + K +C+ + ++ IY L+ PR + GFT LH+AV+ +T + V FP
Sbjct: 451 VCISTKTQCSEEDQCKINKQIYNLIHLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFP 510
Query: 178 SLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCP--------AIVNALTEAGAHMDATN 229
+ V K+L DCGA+ ++ D + N+ LHI Q N P +I+ +L EAGAH D TN
Sbjct: 511 NALVTKLLLDCGAEVNAVDNEGNSALHIIVQYNRPISDFLTLHSIIISLVEAGAHTDMTN 570
Query: 230 AFKKTAYELLE---EKLLARGTMQPFNYVTLQCLAAQALDKNKIPYKGFIPEDLEAFIEL 286
KT + ++L + M+ ++L+CLAA+A+ N I Y+ IP LE F+
Sbjct: 571 KQNKTPLDKSTTGVSEILLKTQMK----MSLKCLAARAVRANDINYQDQIPRTLEEFVGF 626
Query: 287 H 287
H
Sbjct: 627 H 627
Score = 29.3 bits (64), Expect = 4.2
Identities = 18/54 (33%), Positives = 26/54 (48%)
Query: 181 VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
VVK+L GA+ + N+TPL A + IV L E A++ N + T
Sbjct: 103 VVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIVKYLVENNANISIANKYDNT 156
>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
Length = 300
Score = 49.7 bits (117), Expect = 3e-06
Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Query: 181 VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYELLE 240
+V++L D GAD + RD NTPLH+AA N ++ L GA +DA + +T L +
Sbjct: 158 IVQLLLDHGADPNQRDGLGNTPLHLAACTNHVPVITTLLRGGARVDALDRAGRTPLHLAK 217
Query: 241 EKL--LARGTMQPFNYVTLQ 258
KL L G Q V L+
Sbjct: 218 SKLNILQEGHAQCLEAVRLE 237
Score = 28.1 bits (61), Expect = 9.3
Identities = 18/60 (30%), Positives = 26/60 (43%)
Query: 179 LHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYEL 238
+ V+ L + GAD + D T LH A+ N IV L + GA + + T L
Sbjct: 123 VETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQRDGLGNTPLHL 182
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 48.5 bits (114), Expect = 7e-06
Identities = 50/197 (25%), Positives = 79/197 (40%), Gaps = 23/197 (11%)
Query: 46 TPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRD 105
TP+ ++ + + +L++ A +L T G L + R VE L LL +
Sbjct: 505 TPLHCAARIGHTNMVKLLLENNA-NPNLATTAGHTPLH--IAAREGHVETVLALLEKEAS 561
Query: 106 SAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDT 165
A K LH+ KV + + R GKNG TPLH+AV +
Sbjct: 562 QACMTKKGFTPLHVAAKYGKVR-------VAELLLERDAHPNAAGKNGLTPLHVAVHHN- 613
Query: 166 TNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHM 225
+L +VK+L G S ++ TPLHIAA+ N + +L + G
Sbjct: 614 ------------NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA 661
Query: 226 DATNAFKKTAYELLEEK 242
+A + T L ++
Sbjct: 662 NAESVQGVTPLHLAAQE 678
Score = 45.4 bits (106), Expect = 6e-05
Identities = 56/235 (23%), Positives = 96/235 (40%), Gaps = 42/235 (17%)
Query: 17 VYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQ 76
+ A +G E L Y ++ + + TP+ ++ + E+ ++L++ A ++ T+
Sbjct: 117 IAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN-GANQNVATE 175
Query: 77 IGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLK 136
GF L L + V L + + L L++ + + T
Sbjct: 176 DGFTPLAVALQQGHENVVAHL---------INYGTKGKVRLPALHIAARNDDT------- 219
Query: 137 HQTIYRLLKCAPR----GKNGFTPLHMAVDKDTTNVGRYPVGRFPS-----------LHV 181
+T LL+ P K GFTPLH+A + NV + + R S LH+
Sbjct: 220 -RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHI 278
Query: 182 ---------VKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
V++L D GA +++ D TPLH AA+N I L + GA + A
Sbjct: 279 ASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQA 333
Score = 45.4 bits (106), Expect = 6e-05
Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 20/97 (20%)
Query: 151 KNGFTPLHMAVDKDTTNVGRY-----------PVGRFPSLHVV---------KVLFDCGA 190
KNG +P+HMA D + R + LHV KVL D GA
Sbjct: 336 KNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 395
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
+SR + TPLHIA + N ++ L + GA +DA
Sbjct: 396 KPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 432
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 134 HLKHQTIYRLL-----KCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDC 188
H H + ++L K R NGFTPLH+A K+ + V+++L
Sbjct: 380 HCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN-------------HVRVMELLLKT 426
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
GA D+ TPLH+A+ IV L + GA + +N +T
Sbjct: 427 GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVET 472
Score = 37.0 bits (84), Expect = 0.020
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 58/248 (23%)
Query: 19 ADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIG 78
A +++C L +Y ++ L+ LTP+ ++ + + VL D AK + G
Sbjct: 346 AQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRV-AKVLLDKGAKPNSRALNG 404
Query: 79 FADL-----------MGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVE 127
F L M +L K ++ + P A F L I+ +LL +
Sbjct: 405 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL----QRG 460
Query: 128 CTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFD 187
+P+ ++K +T PLHMA T V +Y L
Sbjct: 461 ASPNVSNVKVET----------------PLHMAARAGHTEVAKY-------------LLQ 491
Query: 188 CGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA-------------HMDATNAFKKT 234
A +++ D+ TPLH AA+ +V L E A H+ A +T
Sbjct: 492 NKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVET 551
Query: 235 AYELLEEK 242
LLE++
Sbjct: 552 VLALLEKE 559
Score = 36.2 bits (82), Expect = 0.034
Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 22/101 (21%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
+ + GFTPL+MA ++ L VVK L + GA+++ D TPL +A Q
Sbjct: 140 QSQKGFTPLYMAAQEN-------------HLEVVKFLLENGANQNVATEDGFTPLAVALQ 186
Query: 209 NNCPAIVNALTEAGA---------HMDATNAFKKTAYELLE 240
+V L G H+ A N +TA LL+
Sbjct: 187 QGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQ 227
Score = 32.3 bits (72), Expect = 0.49
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 20/93 (21%)
Query: 151 KNGFTPLHMAVDKD-----------------TTNVGRYPV---GRFPSLHVVKVLFDCGA 190
K+G TPLH+ + TT +G P+ + ++ +VK L A
Sbjct: 699 KSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQA 758
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA 223
D +++ +PLH AAQ IV L + GA
Sbjct: 759 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 791
Score = 31.2 bits (69), Expect = 1.1
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 16/94 (17%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVG-------RFPSLHVVK---------VLFDCGADRDS 194
++GFTPL +A+ + NV + + R P+LH+ VL + D
Sbjct: 175 EDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDV 234
Query: 195 RDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDAT 228
TPLHIAA + L GA ++ T
Sbjct: 235 LSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 268
Score = 28.9 bits (63), Expect = 5.4
Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 20/96 (20%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGR-----------FPSLH---------VVKVLFDCGA 190
+NG TPLH+A + + R + R LH + ++L D GA
Sbjct: 270 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 329
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMD 226
++ + +P+H+AAQ + V L + A +D
Sbjct: 330 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 365
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 48.5 bits (114), Expect = 7e-06
Identities = 50/197 (25%), Positives = 79/197 (40%), Gaps = 23/197 (11%)
Query: 46 TPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRD 105
TP+ ++ + + +L++ A +L T G L + R VE L LL +
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNA-NPNLATTAGHTPLH--IAAREGHVETVLALLEKEAS 528
Query: 106 SAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDT 165
A K LH+ KV + + R GKNG TPLH+AV +
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVR-------VAELLLERDAHPNAAGKNGLTPLHVAVHHN- 580
Query: 166 TNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHM 225
+L +VK+L G S ++ TPLHIAA+ N + +L + G
Sbjct: 581 ------------NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA 628
Query: 226 DATNAFKKTAYELLEEK 242
+A + T L ++
Sbjct: 629 NAESVQGVTPLHLAAQE 645
Score = 45.4 bits (106), Expect = 6e-05
Identities = 56/235 (23%), Positives = 96/235 (40%), Gaps = 42/235 (17%)
Query: 17 VYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQ 76
+ A +G E L Y ++ + + TP+ ++ + E+ ++L++ A ++ T+
Sbjct: 84 IAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN-GANQNVATE 142
Query: 77 IGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLK 136
GF L L + V L + + L L++ + + T
Sbjct: 143 DGFTPLAVALQQGHENVVAHL---------INYGTKGKVRLPALHIAARNDDT------- 186
Query: 137 HQTIYRLLKCAPR----GKNGFTPLHMAVDKDTTNVGRYPVGRFPS-----------LHV 181
+T LL+ P K GFTPLH+A + NV + + R S LH+
Sbjct: 187 -RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHI 245
Query: 182 ---------VKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
V++L D GA +++ D TPLH AA+N I L + GA + A
Sbjct: 246 ASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQA 300
Score = 45.4 bits (106), Expect = 6e-05
Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 20/97 (20%)
Query: 151 KNGFTPLHMAVDKDTTNVGRY-----------PVGRFPSLHVV---------KVLFDCGA 190
KNG +P+HMA D + R + LHV KVL D GA
Sbjct: 303 KNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
+SR + TPLHIA + N ++ L + GA +DA
Sbjct: 363 KPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 134 HLKHQTIYRLL-----KCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDC 188
H H + ++L K R NGFTPLH+A K+ + V+++L
Sbjct: 347 HCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN-------------HVRVMELLLKT 393
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
GA D+ TPLH+A+ IV L + GA + +N +T
Sbjct: 394 GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVET 439
Score = 37.0 bits (84), Expect = 0.020
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 58/248 (23%)
Query: 19 ADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIG 78
A +++C L +Y ++ L+ LTP+ ++ + + VL D AK + G
Sbjct: 313 AQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRV-AKVLLDKGAKPNSRALNG 371
Query: 79 FADL-----------MGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVE 127
F L M +L K ++ + P A F L I+ +LL +
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL----QRG 427
Query: 128 CTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFD 187
+P+ ++K +T PLHMA T V +Y L
Sbjct: 428 ASPNVSNVKVET----------------PLHMAARAGHTEVAKY-------------LLQ 458
Query: 188 CGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA-------------HMDATNAFKKT 234
A +++ D+ TPLH AA+ +V L E A H+ A +T
Sbjct: 459 NKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVET 518
Query: 235 AYELLEEK 242
LLE++
Sbjct: 519 VLALLEKE 526
Score = 36.2 bits (82), Expect = 0.034
Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 22/101 (21%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
+ + GFTPL+MA ++ L VVK L + GA+++ D TPL +A Q
Sbjct: 107 QSQKGFTPLYMAAQEN-------------HLEVVKFLLENGANQNVATEDGFTPLAVALQ 153
Query: 209 NNCPAIVNALTEAGA---------HMDATNAFKKTAYELLE 240
+V L G H+ A N +TA LL+
Sbjct: 154 QGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQ 194
Score = 32.3 bits (72), Expect = 0.49
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 20/93 (21%)
Query: 151 KNGFTPLHMAVDKD-----------------TTNVGRYPV---GRFPSLHVVKVLFDCGA 190
K+G TPLH+ + TT +G P+ + ++ +VK L A
Sbjct: 666 KSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQA 725
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA 223
D +++ +PLH AAQ IV L + GA
Sbjct: 726 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 758
Score = 31.2 bits (69), Expect = 1.1
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 16/94 (17%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVG-------RFPSLHVVK---------VLFDCGADRDS 194
++GFTPL +A+ + NV + + R P+LH+ VL + D
Sbjct: 142 EDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDV 201
Query: 195 RDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDAT 228
TPLHIAA + L GA ++ T
Sbjct: 202 LSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Score = 28.9 bits (63), Expect = 5.4
Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 20/96 (20%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGR-----------FPSLH---------VVKVLFDCGA 190
+NG TPLH+A + + R + R LH + ++L D GA
Sbjct: 237 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 296
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMD 226
++ + +P+H+AAQ + V L + A +D
Sbjct: 297 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 48.5 bits (114), Expect = 7e-06
Identities = 50/197 (25%), Positives = 79/197 (40%), Gaps = 23/197 (11%)
Query: 46 TPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRD 105
TP+ ++ + + +L++ A +L T G L + R VE L LL +
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNA-NPNLATTAGHTPLH--IAAREGHVETVLALLEKEAS 528
Query: 106 SAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDT 165
A K LH+ KV + + R GKNG TPLH+AV +
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVR-------VAELLLERDAHPNAAGKNGLTPLHVAVHHN- 580
Query: 166 TNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHM 225
+L +VK+L G S ++ TPLHIAA+ N + +L + G
Sbjct: 581 ------------NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA 628
Query: 226 DATNAFKKTAYELLEEK 242
+A + T L ++
Sbjct: 629 NAESVQGVTPLHLAAQE 645
Score = 45.4 bits (106), Expect = 6e-05
Identities = 56/235 (23%), Positives = 96/235 (40%), Gaps = 42/235 (17%)
Query: 17 VYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQ 76
+ A +G E L Y ++ + + TP+ ++ + E+ ++L++ A ++ T+
Sbjct: 84 IAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN-GANQNVATE 142
Query: 77 IGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLK 136
GF L L + V L + + L L++ + + T
Sbjct: 143 DGFTPLAVALQQGHENVVAHL---------INYGTKGKVRLPALHIAARNDDT------- 186
Query: 137 HQTIYRLLKCAPR----GKNGFTPLHMAVDKDTTNVGRYPVGRFPS-----------LHV 181
+T LL+ P K GFTPLH+A + NV + + R S LH+
Sbjct: 187 -RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHI 245
Query: 182 ---------VKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
V++L D GA +++ D TPLH AA+N I L + GA + A
Sbjct: 246 ASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQA 300
Score = 45.4 bits (106), Expect = 6e-05
Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 20/97 (20%)
Query: 151 KNGFTPLHMAVDKDTTNVGRY-----------PVGRFPSLHVV---------KVLFDCGA 190
KNG +P+HMA D + R + LHV KVL D GA
Sbjct: 303 KNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
+SR + TPLHIA + N ++ L + GA +DA
Sbjct: 363 KPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 134 HLKHQTIYRLL-----KCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDC 188
H H + ++L K R NGFTPLH+A K+ + V+++L
Sbjct: 347 HCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN-------------HVRVMELLLKT 393
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
GA D+ TPLH+A+ IV L + GA + +N +T
Sbjct: 394 GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVET 439
Score = 37.0 bits (84), Expect = 0.020
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 58/248 (23%)
Query: 19 ADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIG 78
A +++C L +Y ++ L+ LTP+ ++ + + VL D AK + G
Sbjct: 313 AQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRV-AKVLLDKGAKPNSRALNG 371
Query: 79 FADL-----------MGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVE 127
F L M +L K ++ + P A F L I+ +LL +
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL----QRG 427
Query: 128 CTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFD 187
+P+ ++K +T PLHMA T V +Y L
Sbjct: 428 ASPNVSNVKVET----------------PLHMAARAGHTEVAKY-------------LLQ 458
Query: 188 CGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA-------------HMDATNAFKKT 234
A +++ D+ TPLH AA+ +V L E A H+ A +T
Sbjct: 459 NKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVET 518
Query: 235 AYELLEEK 242
LLE++
Sbjct: 519 VLALLEKE 526
Score = 36.2 bits (82), Expect = 0.034
Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 22/101 (21%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
+ + GFTPL+MA ++ L VVK L + GA+++ D TPL +A Q
Sbjct: 107 QSQKGFTPLYMAAQEN-------------HLEVVKFLLENGANQNVATEDGFTPLAVALQ 153
Query: 209 NNCPAIVNALTEAGA---------HMDATNAFKKTAYELLE 240
+V L G H+ A N +TA LL+
Sbjct: 154 QGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQ 194
Score = 32.3 bits (72), Expect = 0.49
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 20/93 (21%)
Query: 151 KNGFTPLHMAVDKD-----------------TTNVGRYPV---GRFPSLHVVKVLFDCGA 190
K+G TPLH+ + TT +G P+ + ++ +VK L A
Sbjct: 666 KSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQA 725
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA 223
D +++ +PLH AAQ IV L + GA
Sbjct: 726 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 758
Score = 31.2 bits (69), Expect = 1.1
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 16/94 (17%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVG-------RFPSLHVVK---------VLFDCGADRDS 194
++GFTPL +A+ + NV + + R P+LH+ VL + D
Sbjct: 142 EDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDV 201
Query: 195 RDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDAT 228
TPLHIAA + L GA ++ T
Sbjct: 202 LSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Score = 28.9 bits (63), Expect = 5.4
Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 20/96 (20%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGR-----------FPSLH---------VVKVLFDCGA 190
+NG TPLH+A + + R + R LH + ++L D GA
Sbjct: 237 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 296
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMD 226
++ + +P+H+AAQ + V L + A +D
Sbjct: 297 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 48.5 bits (114), Expect = 7e-06
Identities = 50/197 (25%), Positives = 79/197 (40%), Gaps = 23/197 (11%)
Query: 46 TPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRD 105
TP+ ++ + + +L++ A +L T G L + R VE L LL +
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNA-NPNLATTAGHTPLH--IAAREGHVETVLALLEKEAS 528
Query: 106 SAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDT 165
A K LH+ KV + + R GKNG TPLH+AV +
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVR-------VAELLLERDAHPNAAGKNGLTPLHVAVHHN- 580
Query: 166 TNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHM 225
+L +VK+L G S ++ TPLHIAA+ N + +L + G
Sbjct: 581 ------------NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA 628
Query: 226 DATNAFKKTAYELLEEK 242
+A + T L ++
Sbjct: 629 NAESVQGVTPLHLAAQE 645
Score = 45.4 bits (106), Expect = 6e-05
Identities = 56/235 (23%), Positives = 96/235 (40%), Gaps = 42/235 (17%)
Query: 17 VYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQ 76
+ A +G E L Y ++ + + TP+ ++ + E+ ++L++ A ++ T+
Sbjct: 84 IAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN-GANQNVATE 142
Query: 77 IGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLK 136
GF L L + V L + + L L++ + + T
Sbjct: 143 DGFTPLAVALQQGHENVVAHL---------INYGTKGKVRLPALHIAARNDDT------- 186
Query: 137 HQTIYRLLKCAPR----GKNGFTPLHMAVDKDTTNVGRYPVGRFPS-----------LHV 181
+T LL+ P K GFTPLH+A + NV + + R S LH+
Sbjct: 187 -RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHI 245
Query: 182 ---------VKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
V++L D GA +++ D TPLH AA+N I L + GA + A
Sbjct: 246 ASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQA 300
Score = 45.4 bits (106), Expect = 6e-05
Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 20/97 (20%)
Query: 151 KNGFTPLHMAVDKDTTNVGRY-----------PVGRFPSLHVV---------KVLFDCGA 190
KNG +P+HMA D + R + LHV KVL D GA
Sbjct: 303 KNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
+SR + TPLHIA + N ++ L + GA +DA
Sbjct: 363 KPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 134 HLKHQTIYRLL-----KCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDC 188
H H + ++L K R NGFTPLH+A K+ + V+++L
Sbjct: 347 HCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN-------------HVRVMELLLKT 393
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
GA D+ TPLH+A+ IV L + GA + +N +T
Sbjct: 394 GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVET 439
Score = 37.0 bits (84), Expect = 0.020
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 58/248 (23%)
Query: 19 ADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIG 78
A +++C L +Y ++ L+ LTP+ ++ + + VL D AK + G
Sbjct: 313 AQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRV-AKVLLDKGAKPNSRALNG 371
Query: 79 FADL-----------MGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVE 127
F L M +L K ++ + P A F L I+ +LL +
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL----QRG 427
Query: 128 CTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFD 187
+P+ ++K +T PLHMA T V +Y L
Sbjct: 428 ASPNVSNVKVET----------------PLHMAARAGHTEVAKY-------------LLQ 458
Query: 188 CGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA-------------HMDATNAFKKT 234
A +++ D+ TPLH AA+ +V L E A H+ A +T
Sbjct: 459 NKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVET 518
Query: 235 AYELLEEK 242
LLE++
Sbjct: 519 VLALLEKE 526
Score = 36.2 bits (82), Expect = 0.034
Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 22/101 (21%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
+ + GFTPL+MA ++ L VVK L + GA+++ D TPL +A Q
Sbjct: 107 QSQKGFTPLYMAAQEN-------------HLEVVKFLLENGANQNVATEDGFTPLAVALQ 153
Query: 209 NNCPAIVNALTEAGA---------HMDATNAFKKTAYELLE 240
+V L G H+ A N +TA LL+
Sbjct: 154 QGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQ 194
Score = 32.3 bits (72), Expect = 0.49
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 20/93 (21%)
Query: 151 KNGFTPLHMAVDKD-----------------TTNVGRYPV---GRFPSLHVVKVLFDCGA 190
K+G TPLH+ + TT +G P+ + ++ +VK L A
Sbjct: 666 KSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQA 725
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA 223
D +++ +PLH AAQ IV L + GA
Sbjct: 726 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 758
Score = 31.2 bits (69), Expect = 1.1
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 16/94 (17%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVG-------RFPSLHVVK---------VLFDCGADRDS 194
++GFTPL +A+ + NV + + R P+LH+ VL + D
Sbjct: 142 EDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDV 201
Query: 195 RDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDAT 228
TPLHIAA + L GA ++ T
Sbjct: 202 LSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Score = 28.9 bits (63), Expect = 5.4
Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 20/96 (20%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGR-----------FPSLH---------VVKVLFDCGA 190
+NG TPLH+A + + R + R LH + ++L D GA
Sbjct: 237 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 296
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMD 226
++ + +P+H+AAQ + V L + A +D
Sbjct: 297 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 48.5 bits (114), Expect = 7e-06
Identities = 50/197 (25%), Positives = 79/197 (40%), Gaps = 23/197 (11%)
Query: 46 TPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRD 105
TP+ ++ + + +L++ A +L T G L + R VE L LL +
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNA-NPNLATTAGHTPLH--IAAREGHVETVLALLEKEAS 528
Query: 106 SAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDT 165
A K LH+ KV + + R GKNG TPLH+AV +
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVR-------VAELLLERDAHPNAAGKNGLTPLHVAVHHN- 580
Query: 166 TNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHM 225
+L +VK+L G S ++ TPLHIAA+ N + +L + G
Sbjct: 581 ------------NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA 628
Query: 226 DATNAFKKTAYELLEEK 242
+A + T L ++
Sbjct: 629 NAESVQGVTPLHLAAQE 645
Score = 45.4 bits (106), Expect = 6e-05
Identities = 56/235 (23%), Positives = 96/235 (40%), Gaps = 42/235 (17%)
Query: 17 VYADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQ 76
+ A +G E L Y ++ + + TP+ ++ + E+ ++L++ A ++ T+
Sbjct: 84 IAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN-GANQNVATE 142
Query: 77 IGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLK 136
GF L L + V L + + L L++ + + T
Sbjct: 143 DGFTPLAVALQQGHENVVAHL---------INYGTKGKVRLPALHIAARNDDT------- 186
Query: 137 HQTIYRLLKCAPR----GKNGFTPLHMAVDKDTTNVGRYPVGRFPS-----------LHV 181
+T LL+ P K GFTPLH+A + NV + + R S LH+
Sbjct: 187 -RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHI 245
Query: 182 ---------VKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
V++L D GA +++ D TPLH AA+N I L + GA + A
Sbjct: 246 ASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQA 300
Score = 45.4 bits (106), Expect = 6e-05
Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 20/97 (20%)
Query: 151 KNGFTPLHMAVDKDTTNVGRY-----------PVGRFPSLHVV---------KVLFDCGA 190
KNG +P+HMA D + R + LHV KVL D GA
Sbjct: 303 KNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
+SR + TPLHIA + N ++ L + GA +DA
Sbjct: 363 KPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 134 HLKHQTIYRLL-----KCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDC 188
H H + ++L K R NGFTPLH+A K+ + V+++L
Sbjct: 347 HCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN-------------HVRVMELLLKT 393
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
GA D+ TPLH+A+ IV L + GA + +N +T
Sbjct: 394 GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVET 439
Score = 37.0 bits (84), Expect = 0.020
Identities = 56/248 (22%), Positives = 92/248 (37%), Gaps = 58/248 (23%)
Query: 19 ADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIG 78
A +++C L +Y ++ L+ LTP+ ++ + + VL D AK + G
Sbjct: 313 AQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRV-AKVLLDKGAKPNSRALNG 371
Query: 79 FADL-----------MGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVE 127
F L M +L K ++ + P A F L I+ +LL +
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL----QRG 427
Query: 128 CTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFD 187
+P+ ++K +T PLHMA T V +Y L
Sbjct: 428 ASPNVSNVKVET----------------PLHMAARAGHTEVAKY-------------LLQ 458
Query: 188 CGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA-------------HMDATNAFKKT 234
A +++ D+ TPLH AA+ +V L E A H+ A +T
Sbjct: 459 NKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVET 518
Query: 235 AYELLEEK 242
LLE++
Sbjct: 519 VLALLEKE 526
Score = 36.2 bits (82), Expect = 0.034
Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 22/101 (21%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
+ + GFTPL+MA ++ L VVK L + GA+++ D TPL +A Q
Sbjct: 107 QSQKGFTPLYMAAQEN-------------HLEVVKFLLENGANQNVATEDGFTPLAVALQ 153
Query: 209 NNCPAIVNALTEAGA---------HMDATNAFKKTAYELLE 240
+V L G H+ A N +TA LL+
Sbjct: 154 QGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQ 194
Score = 32.3 bits (72), Expect = 0.49
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 20/93 (21%)
Query: 151 KNGFTPLHMAVDKD-----------------TTNVGRYPV---GRFPSLHVVKVLFDCGA 190
K+G TPLH+ + TT +G P+ + ++ +VK L A
Sbjct: 666 KSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQA 725
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA 223
D +++ +PLH AAQ IV L + GA
Sbjct: 726 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 758
Score = 31.2 bits (69), Expect = 1.1
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 16/94 (17%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVG-------RFPSLHVVK---------VLFDCGADRDS 194
++GFTPL +A+ + NV + + R P+LH+ VL + D
Sbjct: 142 EDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDV 201
Query: 195 RDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDAT 228
TPLHIAA + L GA ++ T
Sbjct: 202 LSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Score = 28.9 bits (63), Expect = 5.4
Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 20/96 (20%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGR-----------FPSLH---------VVKVLFDCGA 190
+NG TPLH+A + + R + R LH + ++L D GA
Sbjct: 237 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 296
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMD 226
++ + +P+H+AAQ + V L + A +D
Sbjct: 297 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
>gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo
sapiens]
Length = 765
Score = 48.1 bits (113), Expect = 9e-06
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 17/118 (14%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
+ G+TPLH+A + NV R V R AD + + + TPLH+AA
Sbjct: 459 REGWTPLHLAAQNNFENVARLLVSR-------------QADPNLHEAEGKTPLHVAAYFG 505
Query: 211 CPAIVNALTEAGAHMDATNAFKKTAYELLEEKLLARGTMQPFNYVTLQCLAAQALDKN 268
++V LT GA +DA +T L E RG ++ ++ ALD++
Sbjct: 506 HVSLVKLLTSQGAELDAQQRNLRTPLHLAVE----RGKVRAIQHLLKSGAVPDALDQS 559
Score = 41.6 bits (96), Expect = 8e-04
Identities = 40/137 (29%), Positives = 61/137 (44%), Gaps = 27/137 (19%)
Query: 116 ILHLLY-------LLEKVECTP---SQEHLKHQTIYRLLKCAP----RGKNGFTPLHMAV 161
I+HLL L V TP + H + + LL+C ++G+TPLH+AV
Sbjct: 608 IIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAV 667
Query: 162 DKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEA 221
+ T L V+ +L + A+ +R+ TP H+AA AI+ L EA
Sbjct: 668 QRSTF------------LSVINLL-EHHANVHARNKVGWTPAHLAALKGNTAILKVLVEA 714
Query: 222 GAHMDATNAFKKTAYEL 238
GA +D + T +L
Sbjct: 715 GAQLDVQDGVSCTPLQL 731
Score = 40.0 bits (92), Expect = 0.002
Identities = 60/232 (25%), Positives = 85/232 (36%), Gaps = 52/232 (22%)
Query: 44 PLTPMSASSFLSFAELFSYVLQDP---AAKGS----LGTQIGFADLMGVLTKRVREVEWA 96
PL + ++F + A L DP A+G + G L+ +LT + E++
Sbjct: 464 PLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQ 523
Query: 97 LQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGK----- 151
+ LR P A + I HLL K P + L L A RGK
Sbjct: 524 QRNLRTPLHLAVERGKVRAIQHLL----KSGAVP--DALDQSGYGPLHTAAARGKYLICK 577
Query: 152 --------------NGFTPLHMAVDK-----------DTTNVGRYPVGRFPSLH------ 180
G+TPLH+A K N+G + LH
Sbjct: 578 MLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHG 637
Query: 181 ---VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATN 229
VV L CGAD ++ + TPLH+A Q + V L E A++ A N
Sbjct: 638 EEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARN 689
Score = 37.0 bits (84), Expect = 0.020
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 13/84 (15%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
++G+ PLH A R +L D GA D+++ + TPLH+AAQNN
Sbjct: 426 EDGWAPLHFAAQNGDDGTAR-------------LLLDHGACVDAQEREGWTPLHLAAQNN 472
Query: 211 CPAIVNALTEAGAHMDATNAFKKT 234
+ L A + A KT
Sbjct: 473 FENVARLLVSRQADPNLHEAEGKT 496
Score = 32.0 bits (71), Expect = 0.64
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 13/76 (17%)
Query: 152 NGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNC 211
+G+TPL +A ++ +L GAD + D D PLH AAQN
Sbjct: 394 SGYTPLLIAAQDQQPDL-------------CALLLAHGADANRVDEDGWAPLHFAAQNGD 440
Query: 212 PAIVNALTEAGAHMDA 227
L + GA +DA
Sbjct: 441 DGTARLLLDHGACVDA 456
>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
Length = 1430
Score = 47.4 bits (111), Expect = 1e-05
Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 17/115 (14%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
K+G LH+AV R + V+K L G D +D NTPLH+A ++
Sbjct: 542 KDGHIALHLAV-------------RRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDG 588
Query: 211 CPAIVNALTEAGAHMDATNAFKKTAYELLEEKLLARGTMQPFNYVTLQCLAAQAL 265
IV AL EA ++D +N + +T L G + Y+ L + +AL
Sbjct: 589 NMPIVVALCEANCNLDISNKYGRTPLHLAAN----NGILDVVRYLCLMGASVEAL 639
Score = 37.0 bits (84), Expect = 0.020
Identities = 35/128 (27%), Positives = 56/128 (43%), Gaps = 22/128 (17%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
+ K+G LH+A R+ V ++L G++ + +D + TPLH AA
Sbjct: 441 KDKSGEMALHVAA-------------RYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAW 487
Query: 209 NNCPAIVNALTEAGAHMDATNAFKKTAYELLEEKLLARGTMQPFNYVTLQCLAAQALDKN 268
+ ++ AL EAG +++ N +T LL ARG + ++CLA D N
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNREGET--PLLTAS--ARG-----YHDIVECLAEHGADLN 538
Query: 269 KIPYKGFI 276
G I
Sbjct: 539 ACDKDGHI 546
Score = 37.0 bits (84), Expect = 0.020
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 13/88 (14%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
++G TPLH+A KD G P +V L + + D + TPLH+AA N
Sbjct: 575 RHGNTPLHVAC-KD---------GNMP---IVVALCEANCNLDISNKYGRTPLHLAANNG 621
Query: 211 CPAIVNALTEAGAHMDATNAFKKTAYEL 238
+V L GA ++A KTA +L
Sbjct: 622 ILDVVRYLCLMGASVEALTTDGKTAEDL 649
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 47.0 bits (110), Expect = 2e-05
Identities = 39/125 (31%), Positives = 52/125 (41%), Gaps = 33/125 (26%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
+NG TPLH+A + TN+ VK+L D G D++ D TPLH AA++
Sbjct: 243 RNGITPLHVASKRGNTNM-------------VKLLLDRGGQIDAKTRDGLTPLHCAARSG 289
Query: 211 CPAIVNALTEAGA-------------HMDATNAFKKTAYELLEEKLLARGTMQPFNYVTL 257
+V L E GA HM A + LL+ K P + VTL
Sbjct: 290 HDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHK-------APVDDVTL 342
Query: 258 QCLAA 262
L A
Sbjct: 343 DYLTA 347
Score = 42.4 bits (98), Expect = 5e-04
Identities = 49/198 (24%), Positives = 80/198 (40%), Gaps = 25/198 (12%)
Query: 46 TPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRD 105
TP+ S+ ++ S +L+ AA SL T+ GF L +V L R D
Sbjct: 511 TPLHISAREGQVDVASVLLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAAD 569
Query: 106 SAQFNKALAIILHLLYLLEKVECTPSQEHLK-HQTIYRLLKCAPRGKNGFTPLHMAVDKD 164
SA N + + Y +KV ++ H T KNG+TPLH+A K+
Sbjct: 570 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHAT----------AKNGYTPLHIAAKKN 619
Query: 165 TTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAH 224
+ + L + GA+ + TPLH+A+Q +V L + GA+
Sbjct: 620 -------------QMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGAN 666
Query: 225 MDATNAFKKTAYELLEEK 242
+ + T+ L ++
Sbjct: 667 IHMSTKSGLTSLHLAAQE 684
Score = 42.0 bits (97), Expect = 6e-04
Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 20/105 (19%)
Query: 151 KNGFTPLHMAVDKDTTNV-----------------GRYPV---GRFPSLHVVKVLFDCGA 190
K+G T LH+A +D NV G P+ + ++ +V L GA
Sbjct: 672 KSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGA 731
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTA 235
+ +++ + TPLH AAQ I+N L + GA +AT A TA
Sbjct: 732 NVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTA 776
Score = 41.6 bits (96), Expect = 8e-04
Identities = 51/220 (23%), Positives = 81/220 (36%), Gaps = 32/220 (14%)
Query: 30 LWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKR 89
L KY +Q LTP+ ++F+ + +LQ+ A+ + + + R
Sbjct: 396 LVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIR---GETALHMAAR 452
Query: 90 VREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTP-SQEHLKHQTIYRLLKCAP 148
+VE LLR + LH+ L K E +H+ H
Sbjct: 453 AGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPD--------A 504
Query: 149 RGKNGFTPLHMAVDKDTTNVGR--------------------YPVGRFPSLHVVKVLFDC 188
NG+TPLH++ + +V + ++ SL V K+L
Sbjct: 505 ATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 564
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDAT 228
A DS + TPLH+AA + + L E GA AT
Sbjct: 565 RAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHAT 604
Score = 40.4 bits (93), Expect = 0.002
Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 18/110 (16%)
Query: 134 HLKHQTIYRLL---KCAP--RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDC 188
H H + +LL + P R NGFTPLH+A K+ + V+++L
Sbjct: 353 HCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNR-------------IKVMELLVKY 399
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYEL 238
GA + TP+H+AA IV L + GA D TN +TA +
Sbjct: 400 GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHM 449
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 20/99 (20%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRY-----------PVGRFPSLHVV---------KVLFDC 188
R KNG +PLHMA D ++ + +LHV K+L D
Sbjct: 307 RTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDK 366
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
A+ ++R + TPLHIA + N ++ L + GA + A
Sbjct: 367 RANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQA 405
Score = 38.1 bits (87), Expect = 0.009
Identities = 50/239 (20%), Positives = 99/239 (41%), Gaps = 35/239 (14%)
Query: 21 SGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFA 80
+G E L K ++ + TP+ ++ + ++ Y+L++ A S T+ GF
Sbjct: 86 AGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLEN-GANQSTATEDGFT 144
Query: 81 DLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHL----K 136
L L + + A+ +L E + + L L++ + + T S L
Sbjct: 145 PLAVALQQGHNQ---AVAILLENDTKGK------VRLPALHIAARKDDTKSAALLLQNDH 195
Query: 137 HQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRD 196
+ + + ++GFTPLH+A + +++V +L + GA D
Sbjct: 196 NADVQSKMMVNRTTESGFTPLHIAA-------------HYGNVNVATLLLNRGAAVDFTA 242
Query: 197 FDNNTPLHIAAQNNCPAIVNALTEAGAHMDA--------TNAFKKTAYELLEEKLLARG 247
+ TPLH+A++ +V L + G +DA + ++ ++ + E LL RG
Sbjct: 243 RNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERG 301
Score = 37.7 bits (86), Expect = 0.012
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 22/103 (21%)
Query: 151 KNGFTPLHMAV----------------DKDTTNV----GRYPVGRFPSLHVVKVLFDCGA 190
++G TP+H+A D TN+ + R + VV+ L GA
Sbjct: 408 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 467
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA--TNAF 231
D+R + TPLHIA++ IV L + AH DA TN +
Sbjct: 468 LVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGY 510
Score = 34.3 bits (77), Expect = 0.13
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 13/68 (19%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
KNG+TPLH A + T H++ VL GA ++ + NT L IA +
Sbjct: 738 KNGYTPLHQAAQQGHT-------------HIINVLLQHGAKPNATTANGNTALAIAKRLG 784
Query: 211 CPAIVNAL 218
++V+ L
Sbjct: 785 YISVVDTL 792
Score = 33.9 bits (76), Expect = 0.17
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 20/94 (21%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSL--------------------HVVKVLFDCGA 190
+NG LH+A + + + +GR S+ VVKVL GA
Sbjct: 41 QNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGA 100
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAH 224
+ +++ + TPL++AAQ N +V L E GA+
Sbjct: 101 NINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 134
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 47.0 bits (110), Expect = 2e-05
Identities = 39/125 (31%), Positives = 52/125 (41%), Gaps = 33/125 (26%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
+NG TPLH+A + TN+ VK+L D G D++ D TPLH AA++
Sbjct: 264 RNGITPLHVASKRGNTNM-------------VKLLLDRGGQIDAKTRDGLTPLHCAARSG 310
Query: 211 CPAIVNALTEAGA-------------HMDATNAFKKTAYELLEEKLLARGTMQPFNYVTL 257
+V L E GA HM A + LL+ K P + VTL
Sbjct: 311 HDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHK-------APVDDVTL 363
Query: 258 QCLAA 262
L A
Sbjct: 364 DYLTA 368
Score = 42.4 bits (98), Expect = 5e-04
Identities = 49/198 (24%), Positives = 80/198 (40%), Gaps = 25/198 (12%)
Query: 46 TPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRD 105
TP+ S+ ++ S +L+ AA SL T+ GF L +V L R D
Sbjct: 532 TPLHISAREGQVDVASVLLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAAD 590
Query: 106 SAQFNKALAIILHLLYLLEKVECTPSQEHLK-HQTIYRLLKCAPRGKNGFTPLHMAVDKD 164
SA N + + Y +KV ++ H T KNG+TPLH+A K+
Sbjct: 591 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHAT----------AKNGYTPLHIAAKKN 640
Query: 165 TTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAH 224
+ + L + GA+ + TPLH+A+Q +V L + GA+
Sbjct: 641 -------------QMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGAN 687
Query: 225 MDATNAFKKTAYELLEEK 242
+ + T+ L ++
Sbjct: 688 IHMSTKSGLTSLHLAAQE 705
Score = 42.0 bits (97), Expect = 6e-04
Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 20/105 (19%)
Query: 151 KNGFTPLHMAVDKDTTNV-----------------GRYPV---GRFPSLHVVKVLFDCGA 190
K+G T LH+A +D NV G P+ + ++ +V L GA
Sbjct: 693 KSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGA 752
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTA 235
+ +++ + TPLH AAQ I+N L + GA +AT A TA
Sbjct: 753 NVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTA 797
Score = 41.6 bits (96), Expect = 8e-04
Identities = 51/220 (23%), Positives = 81/220 (36%), Gaps = 32/220 (14%)
Query: 30 LWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKR 89
L KY +Q LTP+ ++F+ + +LQ+ A+ + + + R
Sbjct: 417 LVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIR---GETALHMAAR 473
Query: 90 VREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTP-SQEHLKHQTIYRLLKCAP 148
+VE LLR + LH+ L K E +H+ H
Sbjct: 474 AGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPD--------A 525
Query: 149 RGKNGFTPLHMAVDKDTTNVGR--------------------YPVGRFPSLHVVKVLFDC 188
NG+TPLH++ + +V + ++ SL V K+L
Sbjct: 526 ATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 585
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDAT 228
A DS + TPLH+AA + + L E GA AT
Sbjct: 586 RAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHAT 625
Score = 40.4 bits (93), Expect = 0.002
Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 18/110 (16%)
Query: 134 HLKHQTIYRLL---KCAP--RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDC 188
H H + +LL + P R NGFTPLH+A K+ + V+++L
Sbjct: 374 HCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNR-------------IKVMELLVKY 420
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYEL 238
GA + TP+H+AA IV L + GA D TN +TA +
Sbjct: 421 GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHM 470
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 20/99 (20%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRY-----------PVGRFPSLHVV---------KVLFDC 188
R KNG +PLHMA D ++ + +LHV K+L D
Sbjct: 328 RTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDK 387
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
A+ ++R + TPLHIA + N ++ L + GA + A
Sbjct: 388 RANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQA 426
Score = 38.1 bits (87), Expect = 0.009
Identities = 50/239 (20%), Positives = 99/239 (41%), Gaps = 35/239 (14%)
Query: 21 SGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFA 80
+G E L K ++ + TP+ ++ + ++ Y+L++ A S T+ GF
Sbjct: 107 AGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLEN-GANQSTATEDGFT 165
Query: 81 DLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHL----K 136
L L + + A+ +L E + + L L++ + + T S L
Sbjct: 166 PLAVALQQGHNQ---AVAILLENDTKGK------VRLPALHIAARKDDTKSAALLLQNDH 216
Query: 137 HQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRD 196
+ + + ++GFTPLH+A + +++V +L + GA D
Sbjct: 217 NADVQSKMMVNRTTESGFTPLHIAA-------------HYGNVNVATLLLNRGAAVDFTA 263
Query: 197 FDNNTPLHIAAQNNCPAIVNALTEAGAHMDA--------TNAFKKTAYELLEEKLLARG 247
+ TPLH+A++ +V L + G +DA + ++ ++ + E LL RG
Sbjct: 264 RNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERG 322
Score = 37.7 bits (86), Expect = 0.012
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 22/103 (21%)
Query: 151 KNGFTPLHMAV----------------DKDTTNV----GRYPVGRFPSLHVVKVLFDCGA 190
++G TP+H+A D TN+ + R + VV+ L GA
Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 488
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA--TNAF 231
D+R + TPLHIA++ IV L + AH DA TN +
Sbjct: 489 LVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGY 531
Score = 34.3 bits (77), Expect = 0.13
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 13/68 (19%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
KNG+TPLH A + T H++ VL GA ++ + NT L IA +
Sbjct: 759 KNGYTPLHQAAQQGHT-------------HIINVLLQHGAKPNATTANGNTALAIAKRLG 805
Query: 211 CPAIVNAL 218
++V+ L
Sbjct: 806 YISVVDTL 813
Score = 33.9 bits (76), Expect = 0.17
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 20/94 (21%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSL--------------------HVVKVLFDCGA 190
+NG LH+A + + + +GR S+ VVKVL GA
Sbjct: 62 QNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGA 121
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAH 224
+ +++ + TPL++AAQ N +V L E GA+
Sbjct: 122 NINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 47.0 bits (110), Expect = 2e-05
Identities = 39/125 (31%), Positives = 52/125 (41%), Gaps = 33/125 (26%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
+NG TPLH+A + TN+ VK+L D G D++ D TPLH AA++
Sbjct: 264 RNGITPLHVASKRGNTNM-------------VKLLLDRGGQIDAKTRDGLTPLHCAARSG 310
Query: 211 CPAIVNALTEAGA-------------HMDATNAFKKTAYELLEEKLLARGTMQPFNYVTL 257
+V L E GA HM A + LL+ K P + VTL
Sbjct: 311 HDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHK-------APVDDVTL 363
Query: 258 QCLAA 262
L A
Sbjct: 364 DYLTA 368
Score = 42.4 bits (98), Expect = 5e-04
Identities = 49/198 (24%), Positives = 80/198 (40%), Gaps = 25/198 (12%)
Query: 46 TPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRD 105
TP+ S+ ++ S +L+ AA SL T+ GF L +V L R D
Sbjct: 532 TPLHISAREGQVDVASVLLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAAD 590
Query: 106 SAQFNKALAIILHLLYLLEKVECTPSQEHLK-HQTIYRLLKCAPRGKNGFTPLHMAVDKD 164
SA N + + Y +KV ++ H T KNG+TPLH+A K+
Sbjct: 591 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHAT----------AKNGYTPLHIAAKKN 640
Query: 165 TTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAH 224
+ + L + GA+ + TPLH+A+Q +V L + GA+
Sbjct: 641 -------------QMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGAN 687
Query: 225 MDATNAFKKTAYELLEEK 242
+ + T+ L ++
Sbjct: 688 IHMSTKSGLTSLHLAAQE 705
Score = 42.0 bits (97), Expect = 6e-04
Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 20/105 (19%)
Query: 151 KNGFTPLHMAVDKDTTNV-----------------GRYPV---GRFPSLHVVKVLFDCGA 190
K+G T LH+A +D NV G P+ + ++ +V L GA
Sbjct: 693 KSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGA 752
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTA 235
+ +++ + TPLH AAQ I+N L + GA +AT A TA
Sbjct: 753 NVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTA 797
Score = 41.6 bits (96), Expect = 8e-04
Identities = 51/220 (23%), Positives = 81/220 (36%), Gaps = 32/220 (14%)
Query: 30 LWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKR 89
L KY +Q LTP+ ++F+ + +LQ+ A+ + + + R
Sbjct: 417 LVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIR---GETALHMAAR 473
Query: 90 VREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTP-SQEHLKHQTIYRLLKCAP 148
+VE LLR + LH+ L K E +H+ H
Sbjct: 474 AGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPD--------A 525
Query: 149 RGKNGFTPLHMAVDKDTTNVGR--------------------YPVGRFPSLHVVKVLFDC 188
NG+TPLH++ + +V + ++ SL V K+L
Sbjct: 526 ATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 585
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDAT 228
A DS + TPLH+AA + + L E GA AT
Sbjct: 586 RAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHAT 625
Score = 40.4 bits (93), Expect = 0.002
Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 18/110 (16%)
Query: 134 HLKHQTIYRLL---KCAP--RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDC 188
H H + +LL + P R NGFTPLH+A K+ + V+++L
Sbjct: 374 HCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNR-------------IKVMELLVKY 420
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYEL 238
GA + TP+H+AA IV L + GA D TN +TA +
Sbjct: 421 GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHM 470
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 20/99 (20%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRY-----------PVGRFPSLHVV---------KVLFDC 188
R KNG +PLHMA D ++ + +LHV K+L D
Sbjct: 328 RTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDK 387
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
A+ ++R + TPLHIA + N ++ L + GA + A
Sbjct: 388 RANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQA 426
Score = 38.1 bits (87), Expect = 0.009
Identities = 50/239 (20%), Positives = 99/239 (41%), Gaps = 35/239 (14%)
Query: 21 SGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFA 80
+G E L K ++ + TP+ ++ + ++ Y+L++ A S T+ GF
Sbjct: 107 AGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLEN-GANQSTATEDGFT 165
Query: 81 DLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHL----K 136
L L + + A+ +L E + + L L++ + + T S L
Sbjct: 166 PLAVALQQGHNQ---AVAILLENDTKGK------VRLPALHIAARKDDTKSAALLLQNDH 216
Query: 137 HQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRD 196
+ + + ++GFTPLH+A + +++V +L + GA D
Sbjct: 217 NADVQSKMMVNRTTESGFTPLHIAA-------------HYGNVNVATLLLNRGAAVDFTA 263
Query: 197 FDNNTPLHIAAQNNCPAIVNALTEAGAHMDA--------TNAFKKTAYELLEEKLLARG 247
+ TPLH+A++ +V L + G +DA + ++ ++ + E LL RG
Sbjct: 264 RNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERG 322
Score = 37.7 bits (86), Expect = 0.012
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 22/103 (21%)
Query: 151 KNGFTPLHMAV----------------DKDTTNV----GRYPVGRFPSLHVVKVLFDCGA 190
++G TP+H+A D TN+ + R + VV+ L GA
Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 488
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA--TNAF 231
D+R + TPLHIA++ IV L + AH DA TN +
Sbjct: 489 LVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGY 531
Score = 34.3 bits (77), Expect = 0.13
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 13/68 (19%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
KNG+TPLH A + T H++ VL GA ++ + NT L IA +
Sbjct: 759 KNGYTPLHQAAQQGHT-------------HIINVLLQHGAKPNATTANGNTALAIAKRLG 805
Query: 211 CPAIVNAL 218
++V+ L
Sbjct: 806 YISVVDTL 813
Score = 33.9 bits (76), Expect = 0.17
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 20/94 (21%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSL--------------------HVVKVLFDCGA 190
+NG LH+A + + + +GR S+ VVKVL GA
Sbjct: 62 QNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGA 121
Query: 191 DRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAH 224
+ +++ + TPL++AAQ N +V L E GA+
Sbjct: 122 NINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155
>gi|169403959 ankyrin repeat domain 53 isoform a [Homo sapiens]
Length = 530
Score = 46.2 bits (108), Expect = 3e-05
Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 9/79 (11%)
Query: 152 NGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNC 211
N TPLH+ + +D T V +L + L + GAD +++ + +TPLH+AA++
Sbjct: 173 NSQTPLHLVIHRDNTTV---------ALPCIYYLLEKGADLNAQTCNGSTPLHLAARDGL 223
Query: 212 PAIVNALTEAGAHMDATNA 230
V L ++GA++ A +A
Sbjct: 224 LDCVKVLVQSGANVHAQDA 242
>gi|169403957 ankyrin repeat domain 53 isoform b [Homo sapiens]
Length = 343
Score = 46.2 bits (108), Expect = 3e-05
Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 9/79 (11%)
Query: 152 NGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNC 211
N TPLH+ + +D T V +L + L + GAD +++ + +TPLH+AA++
Sbjct: 173 NSQTPLHLVIHRDNTTV---------ALPCIYYLLEKGADLNAQTCNGSTPLHLAARDGL 223
Query: 212 PAIVNALTEAGAHMDATNA 230
V L ++GA++ A +A
Sbjct: 224 LDCVKVLVQSGANVHAQDA 242
>gi|24233530 ankyrin repeat domain 44 [Homo sapiens]
Length = 919
Score = 45.8 bits (107), Expect = 4e-05
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 13/81 (16%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
+ K G+TPLH A NV VK L + G + D + NT LHIA
Sbjct: 177 KDKKGYTPLHAAASNGQINV-------------VKHLLNLGVEIDEINVYGNTALHIACY 223
Query: 209 NNCPAIVNALTEAGAHMDATN 229
N A+VN L + GA+++ N
Sbjct: 224 NGQDAVVNELIDYGANVNQPN 244
Score = 42.0 bits (97), Expect = 6e-04
Identities = 50/213 (23%), Positives = 78/213 (36%), Gaps = 53/213 (24%)
Query: 77 IGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVE--------- 127
+G D++ +L EV + P +A N + ++ HLL L +++
Sbjct: 158 MGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTA 217
Query: 128 ----CTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKD------------------T 165
C Q+ + ++ I NGFTPLH A
Sbjct: 218 LHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQ 277
Query: 166 TNVGRYPV------GRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALT 219
+ G+ P+ GRF + L G + D D D NTPLH+AA+ ++N L
Sbjct: 278 SKDGKSPLHMTAVHGRFTRS---QTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLR 334
Query: 220 EAGA-------------HMDATNAFKKTAYELL 239
+GA H+ A NA +LL
Sbjct: 335 TSGADTAKCGIHSMFPLHLAALNAHSDCCRKLL 367
Score = 35.0 bits (79), Expect = 0.076
Identities = 19/58 (32%), Positives = 31/58 (53%)
Query: 178 SLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTA 235
++ +K+L GAD +D TPLH AA N + L GA+++ T+ + +TA
Sbjct: 392 NVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTA 449
Score = 30.8 bits (68), Expect = 1.4
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 16/85 (18%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
R KN TPLH+A + S++V +DR R T LH AA
Sbjct: 78 RDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNV--------SDRGGR-----TALHHAAL 124
Query: 209 NNCPAIVNALTEAGAHMDATNAFKK 233
N +VN L GA++ NAF K
Sbjct: 125 NGHVEMVNLLLAKGANI---NAFDK 146
Score = 30.8 bits (68), Expect = 1.4
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 13/84 (15%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
K+G TPLH+A R+ ++ L GAD + PLH+AA N
Sbjct: 312 KDGNTPLHVAA-------------RYGHELLINTLRTSGADTAKCGIHSMFPLHLAALNA 358
Query: 211 CPAIVNALTEAGAHMDATNAFKKT 234
L +G +D + F +T
Sbjct: 359 HSDCCRKLLSSGFEIDTPDKFGRT 382
Score = 30.4 bits (67), Expect = 1.9
Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 13/55 (23%)
Query: 155 TPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQN 209
TPLH AV S V+VL AD ++RD + TPLH+AA N
Sbjct: 51 TPLHRAVASR-------------SEEAVQVLIKHSADVNARDKNWQTPLHVAAAN 92
Score = 28.9 bits (63), Expect = 5.4
Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 11/90 (12%)
Query: 152 NGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNC 211
N FTPLH A+ D N +G S V RD TPL AA +
Sbjct: 778 NPFTPLHCAIINDHGNCASLLLGAIDSSIV-----------SCRDDKGRTPLRAAAFADH 826
Query: 212 PAIVNALTEAGAHMDATNAFKKTAYELLEE 241
+ L A ++A + KTA + E
Sbjct: 827 VECLQLLLRHSAPVNAVDNSGKTALMMAAE 856
>gi|68131557 ankyrin repeat domain 28 [Homo sapiens]
Length = 1053
Score = 45.4 bits (106), Expect = 6e-05
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 13/81 (16%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
+ K +TPLH A + VVK L D G D + + NTPLH+A
Sbjct: 202 KDKKSYTPLHAAASSGM-------------ISVVKYLLDLGVDMNEPNAYGNTPLHVACY 248
Query: 209 NNCPAIVNALTEAGAHMDATN 229
N +VN L + GA ++ N
Sbjct: 249 NGQDVVVNELIDCGAIVNQKN 269
Score = 39.3 bits (90), Expect = 0.004
Identities = 54/217 (24%), Positives = 87/217 (40%), Gaps = 26/217 (11%)
Query: 36 DMQQSNLEPLTPMSASSFLSFAELFSYVLQDPA---AKGSLG-TQIGFA------DLMGV 85
D+ + E TP+ A+++L AE+ ++ A AK S T + A + + V
Sbjct: 33 DVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQV 92
Query: 86 LTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLK--------H 137
L K +V + + P A NKA+ L+ LL V + H
Sbjct: 93 LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGH 152
Query: 138 QTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDF 197
+ +LL N F D+ + Y + VVK+L GA+ +D
Sbjct: 153 GEMVKLLLSRGANINAFDKK----DRRAIHWAAY----MGHIEVVKLLVSHGAEVTCKDK 204
Query: 198 DNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
+ TPLH AA + ++V L + G M+ NA+ T
Sbjct: 205 KSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNT 241
Score = 38.9 bits (89), Expect = 0.005
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 13/75 (17%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
+ K+G TPLHM T GR+ + + GA D D + NTPLHIAA+
Sbjct: 302 KSKDGKTPLHM-----TALHGRFSRSQ--------TIIQSGAVIDCEDKNGNTPLHIAAR 348
Query: 209 NNCPAIVNALTEAGA 223
++N L +GA
Sbjct: 349 YGHELLINTLITSGA 363
Score = 35.0 bits (79), Expect = 0.076
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 13/84 (15%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
KNG TPLH+A R+ ++ L GAD R PLH+AA +
Sbjct: 337 KNGNTPLHIAA-------------RYGHELLINTLITSGADTAKRGIHGMFPLHLAALSG 383
Query: 211 CPAIVNALTEAGAHMDATNAFKKT 234
L +G +D + F +T
Sbjct: 384 FSDCCRKLLSSGFDIDTPDDFGRT 407
Score = 34.3 bits (77), Expect = 0.13
Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 13/81 (16%)
Query: 155 TPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAI 214
TPLH AV S V+VL AD ++RD + TPLHIAA N
Sbjct: 76 TPLHRAVASC-------------SEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKC 122
Query: 215 VNALTEAGAHMDATNAFKKTA 235
AL ++++ ++ +TA
Sbjct: 123 AEALVPLLSNVNVSDRAGRTA 143
Score = 31.6 bits (70), Expect = 0.84
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 20/100 (20%)
Query: 147 APRGKNGFTPLHMAV----------------DKDTTN-VGR---YPVGRFPSLHVVKVLF 186
A RG +G PLH+A D DT + GR + +L + +L
Sbjct: 366 AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL 425
Query: 187 DCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMD 226
+ GAD + +D +PLH AA N + AL +GA ++
Sbjct: 426 NTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVN 465
Score = 31.2 bits (69), Expect = 1.1
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 26/110 (23%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLH---VVKVLFDCGADRDSRDFDNNTPLHI 205
+ + GFTPLH A S H +++L GAD + + D TPLH+
Sbjct: 268 KNEKGFTPLHFAA---------------ASTHGALCLELLVGNGADVNMKSKDGKTPLHM 312
Query: 206 AAQNNCPAIVNALTEAGAHMDATNAFKKT--------AYELLEEKLLARG 247
A + + + ++GA +D + T +ELL L+ G
Sbjct: 313 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSG 362
Score = 29.3 bits (64), Expect = 4.2
Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 10/81 (12%)
Query: 155 TPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAI 214
TP+H A + R +G + V D +D + TPL ++ N
Sbjct: 619 TPIHAAATNGHSECLRLLIGNAEPQNAV----------DIQDGNGQTPLMLSVLNGHTDC 668
Query: 215 VNALTEAGAHMDATNAFKKTA 235
V +L GA++DA + + +TA
Sbjct: 669 VYSLLNKGANVDAKDKWGRTA 689
Score = 29.3 bits (64), Expect = 4.2
Identities = 17/49 (34%), Positives = 24/49 (48%)
Query: 182 VKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNA 230
V L GA RD TP+H++A ++ AL ++ A MDA A
Sbjct: 702 VDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPA 750
Score = 28.5 bits (62), Expect = 7.1
Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 25/111 (22%)
Query: 152 NGFTPLHMAVDKDTTNVGRYPV--------------GRFPSLHV---------VKVLFDC 188
N F+PLH AV D + GR P LH +++L
Sbjct: 787 NAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTP-LHAAAFTDHVECLQLLLSH 845
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNAL-TEAGAHMDATNAFKKTAYEL 238
A +S D TPL +AA+N V L + A A + + K TA L
Sbjct: 846 NAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHL 896
>gi|30348954 mindbomb homolog 1 [Homo sapiens]
Length = 1006
Score = 44.7 bits (104), Expect = 1e-04
Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 13/81 (16%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
R K TPLH+AV+K L VVK L D G +D + +TPLH A
Sbjct: 526 RNKRRQTPLHIAVNKG-------------HLQVVKTLLDFGCHPSLQDSEGDTPLHDAIS 572
Query: 209 NNCPAIVNALTEAGAHMDATN 229
I+ L EAGA + TN
Sbjct: 573 KKRDDILAVLLEAGADVTITN 593
Score = 31.6 bits (70), Expect = 0.84
Identities = 16/44 (36%), Positives = 23/44 (52%)
Query: 181 VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAH 224
V++VL AD ++R+ TPLHIA +V L + G H
Sbjct: 512 VIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCH 555
Score = 29.6 bits (65), Expect = 3.2
Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 12/75 (16%)
Query: 152 NGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNC 211
+G+T LH+A + V ++ A+ D ++ + T LH+A +
Sbjct: 631 DGYTALHLAALNNHVEVAEL------------LVHQGNANLDIQNVNQQTALHLAVERQH 678
Query: 212 PAIVNALTEAGAHMD 226
IV L AGA +D
Sbjct: 679 TQIVRLLVRAGAKLD 693
>gi|10092619 nuclear factor of kappa light polypeptide gene enhancer
in B-cells inhibitor, alpha [Homo sapiens]
Length = 317
Score = 44.3 bits (103), Expect = 1e-04
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 13/82 (15%)
Query: 155 TPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAI 214
TPLH+AV + P + + L G D + RDF NTPLH+A + C A
Sbjct: 113 TPLHLAV------ITNQP-------EIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS 159
Query: 215 VNALTEAGAHMDATNAFKKTAY 236
V LT++ + K T Y
Sbjct: 160 VGVLTQSCTTPHLHSILKATNY 181
Score = 30.0 bits (66), Expect = 2.4
Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 14/88 (15%)
Query: 152 NGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNN-TPLHIAAQNN 210
NG T LH+A ++ Y L +V++L GAD ++++ N T LH+A
Sbjct: 182 NGHTCLHLA------SIHGY-------LGIVELLVSLGADVNAQEPCNGRTALHLAVDLQ 228
Query: 211 CPAIVNALTEAGAHMDATNAFKKTAYEL 238
P +V+ L + GA ++ + Y+L
Sbjct: 229 NPDLVSLLLKCGADVNRVTYQGYSPYQL 256
>gi|169203021 PREDICTED: similar to Shank2E [Homo sapiens]
Length = 385
Score = 44.3 bits (103), Expect = 1e-04
Identities = 47/188 (25%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 55 SFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALA 114
S ++ +Y L PA+ G G + L+ + V E +L+ + R + +A
Sbjct: 94 SLKDVLNYGLFQPASNGRDGKFLDEERLLREYPQPVGEGVPSLEFRYKKR---VYKQASL 150
Query: 115 IILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRG--------KNGFTPLHMAVDKDTT 166
L L K +H++H+ + ++ K RG + G TPL +A D
Sbjct: 151 DEKQLAKLHTKTNLKKCMDHIQHRLVEKITKMLDRGLDPNFHDPETGETPLTLAAQLDD- 209
Query: 167 NVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMD 226
S+ V+K L + GA D R D T LH AA+ + L E GA D
Sbjct: 210 -----------SVEVIKALKNGGAHLDFRAKDGMTALHKAARARNQVALKTLLELGASPD 258
Query: 227 ATNAFKKT 234
+++ T
Sbjct: 259 YKDSYGLT 266
Score = 30.4 bits (67), Expect = 1.9
Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 180 HVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYELL 239
H+ +LF GAD +++ NT LHI A N + L G + + N +T +++
Sbjct: 313 HLEHLLF-YGADMSAQNASGNTALHICALYNQDSCARVLLFRGGNKELKNYNSQTPFQVK 371
Query: 240 E 240
E
Sbjct: 372 E 372
>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
[Homo sapiens]
Length = 1849
Score = 44.3 bits (103), Expect = 1e-04
Identities = 47/188 (25%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 55 SFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRDSAQFNKALA 114
S ++ +Y L PA+ G G + L+ + V E +L+ + R + +A
Sbjct: 94 SLKDVLNYGLFQPASNGRDGKFLDEERLLREYPQPVGEGVPSLEFRYKKR---VYKQASL 150
Query: 115 IILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRG--------KNGFTPLHMAVDKDTT 166
L L K +H++H+ + ++ K RG + G TPL +A D
Sbjct: 151 DEKQLAKLHTKTNLKKCMDHIQHRLVEKITKMLDRGLDPNFHDPETGETPLTLAAQLDD- 209
Query: 167 NVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMD 226
S+ V+K L + GA D R D T LH AA+ + L E GA D
Sbjct: 210 -----------SVEVIKALKNGGAHLDFRAKDGMTALHKAARARNQVALKTLLELGASPD 258
Query: 227 ATNAFKKT 234
+++ T
Sbjct: 259 YKDSYGLT 266
Score = 29.3 bits (64), Expect = 4.2
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 180 HVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYEL 238
H+ +LF GAD +++ NT LHI A N + L G + + N +T +++
Sbjct: 313 HLEHLLF-YGADMSAQNASGNTALHICALYNQDSCARVLLFRGGNKELKNYNSQTPFQV 370
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 43.9 bits (102), Expect = 2e-04
Identities = 54/209 (25%), Positives = 82/209 (39%), Gaps = 23/209 (11%)
Query: 19 ADSGNIECYIRLWKYALDMQQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGSLGTQIG 78
A SG E L + ++ + TP+ S+ L A++ +LQ A+ + T G
Sbjct: 474 ARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTS-G 532
Query: 79 FADLMGVLTKRVREVEWALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLKHQ 138
+ L L+ R + A LL + K LH+ K+E + +
Sbjct: 533 YTPLH--LSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLE-------VANL 583
Query: 139 TIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFD 198
+ + GK+G TPLH+A D V +L D GA + +
Sbjct: 584 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVAL-------------LLLDQGASPHAAAKN 630
Query: 199 NNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
TPLHIAA+ N I L E GA +A
Sbjct: 631 GYTPLHIAAKKNQMDIATTLLEYGADANA 659
Score = 40.8 bits (94), Expect = 0.001
Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 18/110 (16%)
Query: 134 HLKHQTIYRLL---KCAPRGK--NGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDC 188
H H + ++L K P K NGFTPLH+A K+ + V+++L
Sbjct: 376 HCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNR-------------IKVMELLLKH 422
Query: 189 GADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYEL 238
GA + TP+H+AA IV+ L GA + TN +TA +
Sbjct: 423 GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHM 472
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 25/116 (21%)
Query: 137 HQTIYRLL--KCAP---RGKNGFTPLHMAVDKDTTNVGRY------PVGR-----FPSLH 180
H+ + +L + AP + KNG +PLHMA D N + PV +LH
Sbjct: 313 HEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALH 372
Query: 181 VV---------KVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA 227
V KVL D A+ +++ + TPLHIA + N ++ L + GA + A
Sbjct: 373 VAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQA 428
Score = 39.7 bits (91), Expect = 0.003
Identities = 52/207 (25%), Positives = 87/207 (42%), Gaps = 40/207 (19%)
Query: 46 TPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRD 105
TP+ S+ ++ +++L D A S+ T+ GF L + + ++E A LL++
Sbjct: 534 TPLHLSAREGHEDVAAFLL-DHGASLSITTKKGFTPLH--VAAKYGKLEVANLLLQKSAS 590
Query: 106 SAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLK---CAPRG--KNGFTPLHMA 160
K+ LH+ H +Q + LL +P KNG+TPLH+A
Sbjct: 591 PDAAGKSGLTPLHVA------------AHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 638
Query: 161 VDKDTTNVGRY---------PVGR--FPSLHV---------VKVLFDCGADRDSRDFDNN 200
K+ ++ V R S+H+ V +L A+ + +
Sbjct: 639 AKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGL 698
Query: 201 TPLHIAAQNNCPAIVNALTEAGAHMDA 227
TPLH+AAQ + + L GAH+DA
Sbjct: 699 TPLHLAAQEDRVNVAEVLVNQGAHVDA 725
Score = 39.3 bits (90), Expect = 0.004
Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 16/91 (17%)
Query: 151 KNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNN 210
K+G TPLH+A +D NV +VL + GA D++ TPLH+
Sbjct: 695 KSGLTPLHLAAQEDRVNVA-------------EVLVNQGAHVDAQTKMGYTPLHVGCHYG 741
Query: 211 CPAIVNALTEAGAHMDATNAFKKTAYELLEE 241
IVN L + H NA K Y L +
Sbjct: 742 NIKIVNFLLQ---HSAKVNAKTKNGYTPLHQ 769
Score = 38.9 bits (89), Expect = 0.005
Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 13/72 (18%)
Query: 149 RGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQ 208
+ +NGFTPL+MA ++ L VVK L D GA + D TPL +A Q
Sbjct: 136 QSQNGFTPLYMAAQEN-------------HLEVVKFLLDNGASQSLATEDGFTPLAVALQ 182
Query: 209 NNCPAIVNALTE 220
+V+ L E
Sbjct: 183 QGHDQVVSLLLE 194
Score = 37.7 bits (86), Expect = 0.012
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 27/182 (14%)
Query: 46 TPMSASSFLSFAELFSYVLQDPAAKGSLGTQIGFADLMGVLTKRVREVEWALQLLREPRD 105
TP+ ++ + E+ ++L D A SL T+ GF L L + +V + LL E
Sbjct: 142 TPLYMAAQENHLEVVKFLL-DNGASQSLATEDGFTPLAVALQQGHDQV---VSLLLENDT 197
Query: 106 SAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDT 165
+ + L L++ + + T + L K+GFTPLH+A
Sbjct: 198 KGK------VRLPALHIAARKDDTKAAALLLQNDN----NADVESKSGFTPLHIAA---- 243
Query: 166 TNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHM 225
+ +++V +L + A D ++ TPLH+A++ +V L + GA +
Sbjct: 244 ---------HYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 226 DA 227
DA
Sbjct: 295 DA 296
Score = 36.6 bits (83), Expect = 0.026
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 157 LHMAVDKDTTNV----GRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCP 212
+H +TTNV + R VV+ L GA +++ D+ TPLHI+A+
Sbjct: 453 MHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKA 512
Query: 213 AIVNALTEAGAHMDATNAFKKTAYEL 238
IV L + GA +A T L
Sbjct: 513 DIVQQLLQQGASPNAATTSGYTPLHL 538
Score = 32.3 bits (72), Expect = 0.49
Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 13/74 (17%)
Query: 145 KCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLH 204
K + KNG+TPLH A + T H++ VL A + + NT L
Sbjct: 755 KVNAKTKNGYTPLHQAAQQGHT-------------HIINVLLQNNASPNELTVNGNTALG 801
Query: 205 IAAQNNCPAIVNAL 218
IA + ++V+ L
Sbjct: 802 IARRLGYISVVDTL 815
Score = 32.0 bits (71), Expect = 0.64
Identities = 18/43 (41%), Positives = 27/43 (62%)
Query: 181 VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGA 223
VVKVL GA+ +++ + TPL++AAQ N +V L + GA
Sbjct: 122 VVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGA 164
Score = 28.5 bits (62), Expect = 7.1
Identities = 24/96 (25%), Positives = 34/96 (35%), Gaps = 20/96 (20%)
Query: 153 GFTPLHMAVDKDTTNVGRYPV--------------------GRFPSLHVVKVLFDCGADR 192
G T LHMA V RY V R +V+ L GA
Sbjct: 466 GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 525
Query: 193 DSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDAT 228
++ TPLH++A+ + L + GA + T
Sbjct: 526 NAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSIT 561
>gi|71274109 nuclear factor of kappa light polypeptide gene enhancer
in B-cells inhibitor, epsilon [Homo sapiens]
Length = 500
Score = 43.5 bits (101), Expect = 2e-04
Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 13/95 (13%)
Query: 150 GKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFDCGADRDSRDFDNNTPLHIAAQN 209
G +G T LH+AV+ + V+ L GA D+R + TPLH+AA
Sbjct: 401 GTSGKTALHLAVETQERGL-------------VQFLLQAGAQVDARMLNGCTPLHLAAGR 447
Query: 210 NCPAIVNALTEAGAHMDATNAFKKTAYELLEEKLL 244
I + L +AGA N +T +L EE L+
Sbjct: 448 GLMGISSTLCKAGADSLLRNVEDETPQDLTEESLV 482
>gi|118150656 ankyrin repeat domain 7 [Homo sapiens]
Length = 254
Score = 43.1 bits (100), Expect = 3e-04
Identities = 22/58 (37%), Positives = 38/58 (65%)
Query: 178 SLHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTA 235
SL +V+ L + AD ++++ D TPL +A NN P +V L E GA ++A++ +++TA
Sbjct: 137 SLSLVEKLLEYEADLEAKNKDGYTPLLVAVINNNPKMVKFLLEKGADVNASDNYQRTA 194
Score = 33.5 bits (75), Expect = 0.22
Identities = 27/95 (28%), Positives = 40/95 (42%), Gaps = 20/95 (21%)
Query: 155 TPLHMAVDKDTTNVGRYPV------------GRFPSLHVVK--------VLFDCGADRDS 194
TPLH+A T+V + + + P + V+ +L + GAD D
Sbjct: 61 TPLHLACANGHTDVVLFLIEQQCKINVRDSENKSPLIKAVQCQNEDCATILLNFGADPDL 120
Query: 195 RDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATN 229
RD NT LH A ++V L E A ++A N
Sbjct: 121 RDIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKN 155
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
Length = 2603
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/221 (23%), Positives = 83/221 (37%), Gaps = 33/221 (14%)
Query: 38 QQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGS-LGTQIGFADLM-GVLTKRVREVEW 95
+ N+ TP+S ++ + + +L A S G+++G + LM + V+
Sbjct: 1177 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKL 1236
Query: 96 ALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFT 155
L + + + N+ A+ L C + + + R R K G T
Sbjct: 1237 LLDMGSDINAQIETNRNTALTL---------ACFQGRTEVVSLLLDRKANVEHRAKTGLT 1287
Query: 156 PLHMAVDKDTTNVGRY-------------PVGRFPSLHVV---------KVLFDCGADRD 193
PL A VGR P R +L + ++L GA D
Sbjct: 1288 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHID 1347
Query: 194 SRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
R+ NTPL +AA +V L +AGA +DA + K T
Sbjct: 1348 VRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKIT 1388
Score = 37.0 bits (84), Expect = 0.020
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 14/112 (12%)
Query: 128 CTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFD 187
C E L + R R K GFTPL +A +VG VV++L D
Sbjct: 1091 CAGGHEELVQTLLERGASIEHRDKKGFTPLILAA--TAGHVG-----------VVEILLD 1137
Query: 188 CGADRDSR-DFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYEL 238
GAD +++ + +TPL +A +V L GA+ + N T L
Sbjct: 1138 NGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSL 1189
Score = 31.2 bits (69), Expect = 1.1
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 181 VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA-TNAFKKTAYEL 238
VVKVL + GA + + + +TPL A + L E GA ++ +N FK++A L
Sbjct: 349 VVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTL 407
Score = 28.5 bits (62), Expect = 7.1
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 179 LHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTA 235
L V L GAD + +TPL AAQ +V L AGA++ AT A TA
Sbjct: 547 LEVADFLIKAGADIE---LGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTA 600
>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
Length = 2352
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/221 (23%), Positives = 83/221 (37%), Gaps = 33/221 (14%)
Query: 38 QQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGS-LGTQIGFADLM-GVLTKRVREVEW 95
+ N+ TP+S ++ + + +L A S G+++G + LM + V+
Sbjct: 926 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKL 985
Query: 96 ALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFT 155
L + + + N+ A+ L C + + + R R K G T
Sbjct: 986 LLDMGSDINAQIETNRNTALTL---------ACFQGRTEVVSLLLDRKANVEHRAKTGLT 1036
Query: 156 PLHMAVDKDTTNVGRY-------------PVGRFPSLHVV---------KVLFDCGADRD 193
PL A VGR P R +L + ++L GA D
Sbjct: 1037 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHID 1096
Query: 194 SRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
R+ NTPL +AA +V L +AGA +DA + K T
Sbjct: 1097 VRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKIT 1137
Score = 37.0 bits (84), Expect = 0.020
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 14/112 (12%)
Query: 128 CTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFD 187
C E L + R R K GFTPL +A +VG VV++L D
Sbjct: 840 CAGGHEELVQTLLERGASIEHRDKKGFTPLILAA--TAGHVG-----------VVEILLD 886
Query: 188 CGADRDSR-DFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYEL 238
GAD +++ + +TPL +A +V L GA+ + N T L
Sbjct: 887 NGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSL 938
Score = 31.2 bits (69), Expect = 1.1
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 181 VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA-TNAFKKTAYEL 238
VVKVL + GA + + + +TPL A + L E GA ++ +N FK++A L
Sbjct: 349 VVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTL 407
Score = 28.5 bits (62), Expect = 7.1
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 179 LHVVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTA 235
L V L GAD + +TPL AAQ +V L AGA++ AT A TA
Sbjct: 547 LEVADFLIKAGADIE---LGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTA 600
>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 [Homo
sapiens]
Length = 2542
Score = 42.7 bits (99), Expect = 4e-04
Identities = 51/221 (23%), Positives = 84/221 (38%), Gaps = 33/221 (14%)
Query: 38 QQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGS-LGTQIGFADLM-GVLTKRVREVEW 95
+ N+ TP+S ++ + + +L A S G+++G + LM + V V+
Sbjct: 1149 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKL 1208
Query: 96 ALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFT 155
L + + + N+ A+ L C + + + R R K G T
Sbjct: 1209 LLDMGSDINAQIETNRNTALTL---------ACFQGRAEVVSLLLDRKANVEHRAKTGLT 1259
Query: 156 PLHMAVDKDTTNVGRY-------------PVGRFPSLHVV---------KVLFDCGADRD 193
PL A VGR P R +L + ++L GA D
Sbjct: 1260 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHID 1319
Query: 194 SRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
R+ NTPL +A+ +V L +AGA +DA + K T
Sbjct: 1320 VRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKIT 1360
Score = 37.7 bits (86), Expect = 0.012
Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 14/112 (12%)
Query: 128 CTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFD 187
C E L I R K R K GFTPL +A +VG VV++L D
Sbjct: 1063 CAGGHEELVSVLIARDAKIEHRDKKGFTPLILAA--TAGHVG-----------VVEILLD 1109
Query: 188 CGADRDSR-DFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYEL 238
G D +++ + +TPL +A +V+ L GA+ + N T L
Sbjct: 1110 KGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSL 1161
Score = 30.4 bits (67), Expect = 1.9
Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Query: 181 VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA-TNAFKKTAYEL 238
+VKVL + GA+ + + + +TPL AA + L + GA ++ +N FK++A L
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTL 378
>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
Length = 2617
Score = 42.7 bits (99), Expect = 4e-04
Identities = 51/221 (23%), Positives = 84/221 (38%), Gaps = 33/221 (14%)
Query: 38 QQSNLEPLTPMSASSFLSFAELFSYVLQDPAAKGS-LGTQIGFADLM-GVLTKRVREVEW 95
+ N+ TP+S ++ + + +L A S G+++G + LM + V V+
Sbjct: 1149 EHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKL 1208
Query: 96 ALQLLREPRDSAQFNKALAIILHLLYLLEKVECTPSQEHLKHQTIYRLLKCAPRGKNGFT 155
L + + + N+ A+ L C + + + R R K G T
Sbjct: 1209 LLDMGSDINAQIETNRNTALTL---------ACFQGRAEVVSLLLDRKANVEHRAKTGLT 1259
Query: 156 PLHMAVDKDTTNVGRY-------------PVGRFPSLHVV---------KVLFDCGADRD 193
PL A VGR P R +L + ++L GA D
Sbjct: 1260 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHID 1319
Query: 194 SRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKT 234
R+ NTPL +A+ +V L +AGA +DA + K T
Sbjct: 1320 VRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKIT 1360
Score = 37.7 bits (86), Expect = 0.012
Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 14/112 (12%)
Query: 128 CTPSQEHLKHQTIYRLLKCAPRGKNGFTPLHMAVDKDTTNVGRYPVGRFPSLHVVKVLFD 187
C E L I R K R K GFTPL +A +VG VV++L D
Sbjct: 1063 CAGGHEELVSVLIARDAKIEHRDKKGFTPLILAA--TAGHVG-----------VVEILLD 1109
Query: 188 CGADRDSR-DFDNNTPLHIAAQNNCPAIVNALTEAGAHMDATNAFKKTAYEL 238
G D +++ + +TPL +A +V+ L GA+ + N T L
Sbjct: 1110 KGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSL 1161
Score = 30.4 bits (67), Expect = 1.9
Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Query: 181 VVKVLFDCGADRDSRDFDNNTPLHIAAQNNCPAIVNALTEAGAHMDA-TNAFKKTAYEL 238
+VKVL + GA+ + + + +TPL AA + L + GA ++ +N FK++A L
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTL 378
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,806,860
Number of Sequences: 37866
Number of extensions: 462410
Number of successful extensions: 2084
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 194
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 995
Number of HSP's gapped (non-prelim): 901
length of query: 287
length of database: 18,247,518
effective HSP length: 101
effective length of query: 186
effective length of database: 14,423,052
effective search space: 2682687672
effective search space used: 2682687672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.