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Search of human proteins with 169218115
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169218115 PREDICTED: similar to KIT protein [Homo sapiens]
(245 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169218115 PREDICTED: similar to KIT protein [Homo sapiens] 507 e-144
gi|4557695 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene... 482 e-136
gi|148005039 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoge... 467 e-132
gi|27262659 colony stimulating factor 1 receptor precursor [Homo... 115 5e-26
gi|4505683 platelet-derived growth factor receptor beta precurso... 59 3e-09
gi|5453870 platelet-derived growth factor receptor alpha precurs... 59 4e-09
gi|121114304 fms-related tyrosine kinase 3 [Homo sapiens] 46 3e-05
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 45 4e-05
gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor [... 44 1e-04
gi|229892220 fms-related tyrosine kinase 1 isoform 2 precursor [... 44 1e-04
gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor [... 44 1e-04
gi|229892300 fms-related tyrosine kinase 1 isoform 3 precursor [... 44 1e-04
gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor [... 42 4e-04
gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor [... 42 6e-04
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 40 0.001
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] 40 0.002
gi|110349719 titin isoform N2-A [Homo sapiens] 39 0.003
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 39 0.004
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 39 0.004
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 39 0.004
gi|22902128 PTK7 protein tyrosine kinase 7 isoform c precursor [... 39 0.004
gi|22902126 PTK7 protein tyrosine kinase 7 isoform b precursor [... 39 0.004
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 39 0.005
gi|7657359 contactin 5 isoform long [Homo sapiens] 39 0.005
gi|28373129 contactin 5 isoform short [Homo sapiens] 39 0.005
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 38 0.007
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 38 0.007
gi|66346706 neuronal growth regulator 1 [Homo sapiens] 38 0.007
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 37 0.012
gi|45594240 limbic system-associated membrane protein [Homo sapi... 37 0.012
>gi|169218115 PREDICTED: similar to KIT protein [Homo sapiens]
Length = 245
Score = 507 bits (1305), Expect = e-144
Identities = 245/245 (100%), Positives = 245/245 (100%)
Query: 1 MINTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSEL 60
MINTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSEL
Sbjct: 1 MINTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSEL 60
Query: 61 HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAPGFPEPT 120
HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAPGFPEPT
Sbjct: 61 HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAPGFPEPT 120
Query: 121 IDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDV 180
IDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDV
Sbjct: 121 IDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDV 180
Query: 181 GKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMMKYSG 240
GKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMMKYSG
Sbjct: 181 GKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMMKYSG 240
Query: 241 RLLRR 245
RLLRR
Sbjct: 241 RLLRR 245
>gi|4557695 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
homolog isoform 1 precursor [Homo sapiens]
Length = 976
Score = 482 bits (1240), Expect = e-136
Identities = 232/243 (95%), Positives = 237/243 (97%)
Query: 1 MINTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSEL 60
MINTTVFVNDGENVDLIVEYEAFPKPEHQQWI +NRTFTDKWEDYPKSENESNIRYVSEL
Sbjct: 318 MINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSEL 377
Query: 61 HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAPGFPEPT 120
HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVA GFPEPT
Sbjct: 378 HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPEPT 437
Query: 121 IDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDV 180
IDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDV
Sbjct: 438 IDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDV 497
Query: 181 GKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMMKYSG 240
GKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPM +
Sbjct: 498 GKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMYEVQW 557
Query: 241 RLL 243
+++
Sbjct: 558 KVV 560
>gi|148005039 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
homolog isoform 2 precursor [Homo sapiens]
Length = 972
Score = 467 bits (1202), Expect = e-132
Identities = 228/243 (93%), Positives = 233/243 (95%), Gaps = 4/243 (1%)
Query: 1 MINTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSEL 60
MINTTVFVNDGENVDLIVEYEAFPKPEHQQWI +NRTFTDKWEDYPKSENESNIRYVSEL
Sbjct: 318 MINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSEL 377
Query: 61 HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAPGFPEPT 120
HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVA GFPEPT
Sbjct: 378 HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPEPT 437
Query: 121 IDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDV 180
IDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDV
Sbjct: 438 IDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDV 497
Query: 181 GKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMMKYSG 240
GKTSAYFNFAF KEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPM +
Sbjct: 498 GKTSAYFNFAF----KEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMYEVQW 553
Query: 241 RLL 243
+++
Sbjct: 554 KVV 556
>gi|27262659 colony stimulating factor 1 receptor precursor [Homo
sapiens]
Length = 972
Score = 115 bits (287), Expect = 5e-26
Identities = 84/244 (34%), Positives = 120/244 (49%), Gaps = 17/244 (6%)
Query: 8 VNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSEN---ESNIRYVSELHLTR 64
V GE ++L V EA+P + W L F+D + PK N + R+ L L R
Sbjct: 313 VTVGEGLNLKVMVEAYPGLQGFNWTYLG-PFSDHQPE-PKLANATTKDTYRHTFTLSLPR 370
Query: 65 LKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGM--LQCVAPGFPEPTID 122
LK +E G Y+FL N A+ F + + PE+ +NG L C A G+P+P +
Sbjct: 371 LKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLCAASGYPQPNVT 430
Query: 123 WYFCPGTEQRCS-ASVLPV--DVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYND 179
W C G RC A VL V D S PF K+ VQS + +HN T EC+A+N
Sbjct: 431 WLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNS 490
Query: 180 VGKTSAYFNFAFKGNNKEQIHP--HTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMMK 237
VG S F G + HP LFTP+++ + + ++ +++++L YKY QKP K
Sbjct: 491 VGSGSWAFIPISAGAHT---HPPDEFLFTPVVVACMSIMALLLLLLLLLLYKYKQKP--K 545
Query: 238 YSGR 241
Y R
Sbjct: 546 YQVR 549
>gi|4505683 platelet-derived growth factor receptor beta precursor
[Homo sapiens]
Length = 1106
Score = 59.3 bits (142), Expect = 3e-09
Identities = 61/249 (24%), Positives = 100/249 (40%), Gaps = 29/249 (11%)
Query: 2 INTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDK--WEDYPKSENESNIRYVSE 59
+ T F + L V +EA+P P W NRT D E + N S RYVSE
Sbjct: 322 VGTLQFAELHRSRTLQVVFEAYPPPT-VLWFKDNRTLGDSSAGEIALSTRNVSETRYVSE 380
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEIL----TYDRLVNGMLQCVAPG 115
L L R+K E G YT + D ++F + +N +L ++ ++C G
Sbjct: 381 LTLVRVKVAEAGHYTMRAFHEDAEVQLSFQLQINVPVRVLELSESHPDSGEQTVRCRGRG 440
Query: 116 FPEPTIDWYFCPGTEQRCSASVLPV----------DVQTLNSSGPPFGKLVVQSSIDSSA 165
P+P I W C +RC + P ++T + + V S++
Sbjct: 441 MPQPNIIWSACRDL-KRCPRELPPTLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQH 499
Query: 166 FKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTL-FTPLLIGFVIVAGMMCIIVM 224
+V C N VG+ + + + PH+L F ++I ++ ++ II +
Sbjct: 500 VDRPLSVRCTLRNAVGQDT----------QEVIVVPHSLPFKVVVISAILALVVLTIISL 549
Query: 225 ILTYKYLQK 233
I+ QK
Sbjct: 550 IILIMLWQK 558
>gi|5453870 platelet-derived growth factor receptor alpha precursor
[Homo sapiens]
Length = 1089
Score = 58.9 bits (141), Expect = 4e-09
Identities = 58/245 (23%), Positives = 99/245 (40%), Gaps = 18/245 (7%)
Query: 8 VNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKS-ENESNIRYVSELHLTRLK 66
VN E +VE A+P P W+ N T + + E IRY S+L L R K
Sbjct: 327 VNLHEVKHFVVEVRAYPPPRIS-WLKNNLTLIENLTEITTDVEKIQEIRYRSKLKLIRAK 385
Query: 67 GTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILT-----YDRLVNGMLQCVAPGFPEPTI 121
+ G YT + N D + F + IL + ++C A G P P I
Sbjct: 386 EEDSGHYTIVAQNEDAVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDI 445
Query: 122 DWYFCPGTEQ---RCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYN 178
+W C ++ S ++L +V + + + V+ + + + V C A N
Sbjct: 446 EWMICKDIKKCNNETSWTILANNVSNIITEIHSRDRSTVEGRVTFAKVEETIAVRCLAKN 505
Query: 179 DVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMMKY 238
+G + E T+ +L+ VIV ++ +IV+++ +K QKP +
Sbjct: 506 LLGAENRELKLVAPTLRSEL----TVAAAVLVLLVIV--IISLIVLVVIWK--QKPRYEI 557
Query: 239 SGRLL 243
R++
Sbjct: 558 RWRVI 562
>gi|121114304 fms-related tyrosine kinase 3 [Homo sapiens]
Length = 993
Score = 45.8 bits (107), Expect = 3e-05
Identities = 28/111 (25%), Positives = 45/111 (40%), Gaps = 3/111 (2%)
Query: 71 GTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAPGFPEPTIDWYFCPGTE 130
G Y F N D F + + KP++L C + G+P P+ W C
Sbjct: 414 GEYIFHAENDDAQFTKMFTLNIRRKPQVLA--EASASQASCFSDGYPLPSWTWKKCSDKS 471
Query: 131 QRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVG 181
C+ + V ++ FG+ V S+++ S V+C AYN +G
Sbjct: 472 PNCTEEITE-GVWNRKANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSLG 521
Score = 35.4 bits (80), Expect = 0.045
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 55 RYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYV-NTKPEILT--YDRLVNGM--L 109
R V + + ++ T+ G Y + + N I F V + NT L Y R + L
Sbjct: 123 RGVVSMVILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDAL 182
Query: 110 QCVAPGFPEPTIDWYFCPGTEQRC 133
C++ PEP ++W C + C
Sbjct: 183 VCISESVPEPIVEWVLCDSQGESC 206
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 45.4 bits (106), Expect = 4e-05
Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 16/136 (11%)
Query: 53 NIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGM---- 108
NI + S L ++ L G YT + N + V P+ + R +G+
Sbjct: 647 NIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKA 706
Query: 109 --LQCVAPGFPEPTIDWYFCPGT-EQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSA 165
L C A G+P PTI W F G + L +Q L++ G L+++ ++
Sbjct: 707 VILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSN-----GSLLIKHVVE--- 758
Query: 166 FKHNGTVECKAYNDVG 181
+ +G CK NDVG
Sbjct: 759 -EDSGYYLCKVSNDVG 773
Score = 29.6 bits (65), Expect = 2.5
Identities = 27/108 (25%), Positives = 42/108 (38%), Gaps = 14/108 (12%)
Query: 77 VSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAPGFPEPTIDWYFCPGTEQRCSAS 136
V + D+++++ F VN + + + ++ C A G P T+ WY G E
Sbjct: 15 VFSEDLHSSLYF---VNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPG 71
Query: 137 VLPVDVQTLNSSGPPFGKLVVQSSIDS--SAFKHNGTVECKAYNDVGK 182
+ V P G L + S S H+ T C A N GK
Sbjct: 72 IRHVH---------PNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGK 110
>gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor
[Homo sapiens]
Length = 1338
Score = 44.3 bits (103), Expect = 1e-04
Identities = 40/137 (29%), Positives = 61/137 (44%), Gaps = 30/137 (21%)
Query: 16 LIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTF 75
L ++ +AFP PE W+ T+K Y I+ V+E + G YT
Sbjct: 355 LSMKVKAFPSPE-VVWLKDGLPATEKSARYLTRGYSLIIKDVTE--------EDAGNYTI 405
Query: 76 LVS--NSDVNAAIAFNVYVNTKPEILTYDRLVNG-------------MLQCVAPGFPEPT 120
L+S S+V + + VN KP+I Y++ V+ +L C A G P+PT
Sbjct: 406 LLSIKQSNVFKNLTATLIVNVKPQI--YEKAVSSFPDPALYPLGSRQILTCTAYGIPQPT 463
Query: 121 IDWYFCP----GTEQRC 133
I W++ P +E RC
Sbjct: 464 IKWFWHPCNHNHSEARC 480
>gi|229892220 fms-related tyrosine kinase 1 isoform 2 precursor
[Homo sapiens]
Length = 687
Score = 44.3 bits (103), Expect = 1e-04
Identities = 40/137 (29%), Positives = 61/137 (44%), Gaps = 30/137 (21%)
Query: 16 LIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTF 75
L ++ +AFP PE W+ T+K Y I+ V+E + G YT
Sbjct: 355 LSMKVKAFPSPE-VVWLKDGLPATEKSARYLTRGYSLIIKDVTE--------EDAGNYTI 405
Query: 76 LVS--NSDVNAAIAFNVYVNTKPEILTYDRLVNG-------------MLQCVAPGFPEPT 120
L+S S+V + + VN KP+I Y++ V+ +L C A G P+PT
Sbjct: 406 LLSIKQSNVFKNLTATLIVNVKPQI--YEKAVSSFPDPALYPLGSRQILTCTAYGIPQPT 463
Query: 121 IDWYFCP----GTEQRC 133
I W++ P +E RC
Sbjct: 464 IKWFWHPCNHNHSEARC 480
>gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor
[Homo sapiens]
Length = 541
Score = 44.3 bits (103), Expect = 1e-04
Identities = 40/137 (29%), Positives = 61/137 (44%), Gaps = 30/137 (21%)
Query: 16 LIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTF 75
L ++ +AFP PE W+ T+K Y I+ V+E + G YT
Sbjct: 355 LSMKVKAFPSPE-VVWLKDGLPATEKSARYLTRGYSLIIKDVTE--------EDAGNYTI 405
Query: 76 LVS--NSDVNAAIAFNVYVNTKPEILTYDRLVNG-------------MLQCVAPGFPEPT 120
L+S S+V + + VN KP+I Y++ V+ +L C A G P+PT
Sbjct: 406 LLSIKQSNVFKNLTATLIVNVKPQI--YEKAVSSFPDPALYPLGSRQILTCTAYGIPQPT 463
Query: 121 IDWYFCP----GTEQRC 133
I W++ P +E RC
Sbjct: 464 IKWFWHPCNHNHSEARC 480
>gi|229892300 fms-related tyrosine kinase 1 isoform 3 precursor
[Homo sapiens]
Length = 733
Score = 44.3 bits (103), Expect = 1e-04
Identities = 40/137 (29%), Positives = 61/137 (44%), Gaps = 30/137 (21%)
Query: 16 LIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTF 75
L ++ +AFP PE W+ T+K Y I+ V+E + G YT
Sbjct: 355 LSMKVKAFPSPE-VVWLKDGLPATEKSARYLTRGYSLIIKDVTE--------EDAGNYTI 405
Query: 76 LVS--NSDVNAAIAFNVYVNTKPEILTYDRLVNG-------------MLQCVAPGFPEPT 120
L+S S+V + + VN KP+I Y++ V+ +L C A G P+PT
Sbjct: 406 LLSIKQSNVFKNLTATLIVNVKPQI--YEKAVSSFPDPALYPLGSRQILTCTAYGIPQPT 463
Query: 121 IDWYFCP----GTEQRC 133
I W++ P +E RC
Sbjct: 464 IKWFWHPCNHNHSEARC 480
>gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor
[Homo sapiens]
Length = 1014
Score = 42.4 bits (98), Expect = 4e-04
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 26/141 (18%)
Query: 14 VDLIVEYEAFPKPEHQQWISLNRTFTD------------KWEDYPKSENESNIRYVSE-- 59
V ++ + + P P+ QQ + ++ T KWE +++ S +V++
Sbjct: 496 VQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWE---RADGSSLPEWVTDNA 552
Query: 60 --LHLTRLKGTEGGTYTFLVSN-------SDVNAAIAFNVYVNTKPEILTYDRLVNGMLQ 110
LH R+ + G YT + SN + V +A + +PE T + +LQ
Sbjct: 553 GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQ 612
Query: 111 CVAPGFPEPTIDWYFCPGTEQ 131
C A G P+P I W P E+
Sbjct: 613 CEAQGDPKPLIQWKDKPVPEE 633
Score = 33.9 bits (76), Expect = 0.13
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 59 ELHLTRLKGTEGGTYTFLVSN------SDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCV 112
EL L + ++ G YT +N DVN +A KP+ + G L C+
Sbjct: 375 ELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCL 434
Query: 113 APGFPEPTIDWY 124
P+PT+ WY
Sbjct: 435 TQATPKPTVVWY 446
>gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor
[Homo sapiens]
Length = 1070
Score = 41.6 bits (96), Expect = 6e-04
Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 26/133 (19%)
Query: 14 VDLIVEYEAFPKPEHQQWISLNRTFTD------------KWEDYPKSENESNIRYVSE-- 59
V ++ + + P P+ QQ + ++ T KWE +++ S +V++
Sbjct: 496 VQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWE---RADGSSLPEWVTDNA 552
Query: 60 --LHLTRLKGTEGGTYTFLVSN-------SDVNAAIAFNVYVNTKPEILTYDRLVNGMLQ 110
LH R+ + G YT + SN + V +A + +PE T + +LQ
Sbjct: 553 GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQ 612
Query: 111 CVAPGFPEPTIDW 123
C A G P+P I W
Sbjct: 613 CEAQGDPKPLIQW 625
Score = 33.9 bits (76), Expect = 0.13
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 59 ELHLTRLKGTEGGTYTFLVSN------SDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCV 112
EL L + ++ G YT +N DVN +A KP+ + G L C+
Sbjct: 375 ELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCL 434
Query: 113 APGFPEPTIDWY 124
P+PT+ WY
Sbjct: 435 TQATPKPTVVWY 446
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 40.4 bits (93), Expect = 0.001
Identities = 44/153 (28%), Positives = 59/153 (38%), Gaps = 25/153 (16%)
Query: 44 DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNT------KPE 97
D PK E+ Y L + + + G Y SN A F+V V KP+
Sbjct: 296 DLPKGR-ETKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPRWTKKPQ 354
Query: 98 ILTYDRLVNGMLQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVV 157
Y NG+L C A G P+PTI W R + S PVD + P G +V
Sbjct: 355 SAVYSTGSNGILLCEAEGEPQPTIKW--------RVNGS--PVD------NHPFAGDVVF 398
Query: 158 QSSIDSSAFK--HNGTVECKAYNDVGKTSAYFN 188
I + + H +C+A N G A N
Sbjct: 399 PREISFTNLQPNHTAVYQCEASNVHGTILANAN 431
Score = 30.4 bits (67), Expect = 1.5
Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 15/81 (18%)
Query: 108 MLQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFK 167
+L+C A G P P +DW G LP +T + +GK + I++ +++
Sbjct: 275 LLECFAEGLPTPQVDWNKIGGD--------LPKGRETKEN----YGKTL---KIENVSYQ 319
Query: 168 HNGTVECKAYNDVGKTSAYFN 188
G C A N +G + F+
Sbjct: 320 DKGNYRCTASNFLGTATHDFH 340
>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
Length = 2623
Score = 39.7 bits (91), Expect = 0.002
Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 30/188 (15%)
Query: 6 VFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRL 65
+ V+ G V+L E P P WI N+T + + ++ + L L L
Sbjct: 1755 ITVHSGSTVELKCRAEGRPSPT-VTWILANQTVVS---ESSQGSRQAVVTVDGTLVLHNL 1810
Query: 66 KGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDR--LVNGM------LQCVAPGFP 117
+ G Y + SN ++ + V P ++ R ++ G L C A G P
Sbjct: 1811 SIYDRGFYKCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTP 1870
Query: 118 EPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSS----IDSSAFKHNGTVE 173
+P++ W GTE + +Q NS KL + S+ I + A GT E
Sbjct: 1871 QPSVYWVLSDGTEVK--------PLQFTNS------KLFLFSNGTLYIRNLASSDRGTYE 1916
Query: 174 CKAYNDVG 181
C A + G
Sbjct: 1917 CIATSSTG 1924
Score = 32.7 bits (73), Expect = 0.29
Identities = 31/103 (30%), Positives = 40/103 (38%), Gaps = 26/103 (25%)
Query: 92 VNTKPEILTY-DRLVNGM------LQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQT 144
+ KP ILTY V G+ L CV+ G P+P I W G VD
Sbjct: 2428 IGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSG---------YVVDRPQ 2478
Query: 145 LNSSGPPFGKLVVQSS----IDSSAFKHNGTVECKAYNDVGKT 183
+N GK ++ + I + G CKA N VG T
Sbjct: 2479 IN------GKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHT 2515
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 39.3 bits (90), Expect = 0.003
Identities = 34/142 (23%), Positives = 52/142 (36%), Gaps = 19/142 (13%)
Query: 58 SELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDR----LVNGM---LQ 110
+ L L K T+ GTY +SN A ++V P+ + L NG +
Sbjct: 4823 TSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFE 4882
Query: 111 CVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNG 170
C G P+ + WY G E + + G F + I + +++G
Sbjct: 4883 CQITGTPKIRVSWYL-DGNE-----------ITAIQKHGISFIDGLATFQISGARVENSG 4930
Query: 171 TVECKAYNDVGKTSAYFNFAFK 192
T C+A ND G S K
Sbjct: 4931 TYVCEARNDAGTASCSIELKVK 4952
Score = 30.4 bits (67), Expect = 1.5
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 12/76 (15%)
Query: 109 LQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKH 168
L+C G+P PT+ WY + + +S +D Q SG + + I + +
Sbjct: 962 LECHISGYPSPTVTWY---REDYQIESS---IDFQITFQSG------IARLMIREAFAED 1009
Query: 169 NGTVECKAYNDVGKTS 184
+G C A N+ G S
Sbjct: 1010 SGRFTCSAVNEAGTVS 1025
Score = 29.3 bits (64), Expect = 3.3
Identities = 40/180 (22%), Positives = 66/180 (36%), Gaps = 24/180 (13%)
Query: 13 NVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGT 72
+V+L E P P W+ NR + Y ++ S V LH+T+ ++ G
Sbjct: 4971 DVELECEVTGTP-PFEVTWLKNNREIRSS-KKYTLTDRVS----VFNLHITKCDPSDTGE 5024
Query: 73 YTFLVSNSDVNAAIAFNVYVNTKPEIL------TYDRLVNGMLQCVAPGFPEPTIDWYFC 126
Y +VSN + + + V + P + T + Q G P +I W
Sbjct: 5025 YQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWL-- 5082
Query: 127 PGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAY 186
+L D S L ++ S+D+ H+G C+A N+ G Y
Sbjct: 5083 ------KDDQILDEDDNVYISFVDSVATLQIR-SVDNG---HSGRYTCQAKNESGVERCY 5132
Score = 29.3 bits (64), Expect = 3.3
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 8/86 (9%)
Query: 6 VFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTD-KWEDYPKSENESNIRYVSELHLTR 64
V V G NV L + Y+ PKP W+ + ++ + K+EN+ L +
Sbjct: 27573 VTVRIGHNVHLELPYKGKPKPS-ISWLKDGLPLKESEFVRFSKTENKIT------LSIKN 27625
Query: 65 LKGTEGGTYTFLVSNSDVNAAIAFNV 90
K GG YT ++ N+ A+ V
Sbjct: 27626 AKKEHGGKYTVILDNAVCRIAVPITV 27651
Score = 28.5 bits (62), Expect = 5.6
Identities = 36/152 (23%), Positives = 55/152 (36%), Gaps = 29/152 (19%)
Query: 58 SELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVN---TKPEILTYDRLVN----GMLQ 110
S L L +K ++ GTYT VSN + N++V T E L +L+ L
Sbjct: 4261 SSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLA 4320
Query: 111 CVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNG 170
C G P I W+ R +++ + F + + + +G
Sbjct: 4321 CKVTGTPPIKITWF----ANDR--------EIKESSKHRMSFVESTAVLRLTDVGIEDSG 4368
Query: 171 TVECKAYNDVG----------KTSAYFNFAFK 192
C+A N+ G K S YF FK
Sbjct: 4369 EYMCEAQNEAGSDHCSSIVIVKESPYFTKEFK 4400
Score = 27.7 bits (60), Expect = 9.5
Identities = 12/36 (33%), Positives = 21/36 (58%), Gaps = 6/36 (16%)
Query: 95 KPEILTYD---RLVNG---MLQCVAPGFPEPTIDWY 124
KP+I+ Y R++ G +C G+P+P ++WY
Sbjct: 1840 KPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWY 1875
Score = 27.7 bits (60), Expect = 9.5
Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 13/93 (13%)
Query: 56 YVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAP- 114
+V+EL L ++ E G Y+ LV+N +A+ +++V K RL + ++ +P
Sbjct: 6887 FVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV--KEPATFVKRLADFSVETGSPI 6944
Query: 115 -------GFPEPTIDWY---FCPGTEQRCSASV 137
G P ++ W + +RCS ++
Sbjct: 6945 VLEATYTGTPPISVSWIKDEYLISQSERCSITM 6977
Score = 27.7 bits (60), Expect = 9.5
Identities = 22/95 (23%), Positives = 37/95 (38%), Gaps = 8/95 (8%)
Query: 38 FTDKWEDYPKSENE--SNIRYVSELHLTRLKGTEGGTYTFLVSNSD------VNAAIAFN 89
F DK E +S+N S ++ L +R++ G YT + N ++
Sbjct: 7526 FKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEP 7585
Query: 90 VYVNTKPEILTYDRLVNGMLQCVAPGFPEPTIDWY 124
+ KPE + L+C G PE + W+
Sbjct: 7586 ATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWF 7620
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 38.9 bits (89), Expect = 0.004
Identities = 33/128 (25%), Positives = 50/128 (39%), Gaps = 20/128 (15%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVN------GMLQCVA 113
L L L + G Y+ N+ + ++AF V ++T P I + VN +L C A
Sbjct: 2446 LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQA 2505
Query: 114 PGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVE 173
G P P + W +P+D ++ P G L +Q + A G
Sbjct: 2506 DGVPAPLVSW----------RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDA----GHYL 2551
Query: 174 CKAYNDVG 181
C A N G
Sbjct: 2552 CLASNSAG 2559
Score = 37.0 bits (84), Expect = 0.016
Identities = 40/160 (25%), Positives = 63/160 (39%), Gaps = 28/160 (17%)
Query: 35 NRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNT 94
N T+ + +E + I+ EL + L+G + GTYT N+ A ++ +
Sbjct: 2877 NITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV 2936
Query: 95 KPEILTY---------DRLVNGMLQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTL 145
P T DRL L+C A G P P I W + + PV
Sbjct: 2937 LPVFTTLPGDRSLRLGDRL---WLRCAARGSPTPRIGW----------TVNDRPVTEGVS 2983
Query: 146 NSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSA 185
G G + ++++ + +GT C A N VG+T A
Sbjct: 2984 EQDG---GSTLQRAAVSR---EDSGTYVCWAENRVGRTQA 3017
Score = 36.2 bits (82), Expect = 0.027
Identities = 47/180 (26%), Positives = 68/180 (37%), Gaps = 31/180 (17%)
Query: 6 VFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRL 65
V V + V L+ E P P N T+ P S R +L L R
Sbjct: 321 VAVMEDHLVQLLCEARGVPTP--------NITWFKDGALLPTSTKVVYTRGGRQLQLGRA 372
Query: 66 KGTEGGTYTFLVSNS--DVNAAIAFNVYV-------NTKPEILTYDRLVNGMLQCVAPGF 116
+ ++ G YT SN+ A +VYV +P ++ L+CVA G
Sbjct: 373 QSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGH 432
Query: 117 PEPTIDWY-----FCPGTEQR--CSASVLPVDVQTLNSSG-------PPFGKLVVQSSID 162
P PT+ W+ E R SVL ++ SSG P G+ V+Q S++
Sbjct: 433 PSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVE 492
Score = 36.2 bits (82), Expect = 0.027
Identities = 41/161 (25%), Positives = 62/161 (38%), Gaps = 24/161 (14%)
Query: 43 EDYPKSE-NESNIRYV-SELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILT 100
E P +E NES + S L L G Y+ + S+ A + ++V V P++L
Sbjct: 442 EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLV 501
Query: 101 YDRL-----VNGM---LQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPF 152
+ L + G L C A G P PTI W R + + V V + ++
Sbjct: 502 AEGLGQVTTIVGQPLELPCQASGSPVPTIQWL----QNGRPAEELAGVQVASQGTT---- 553
Query: 153 GKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKG 193
ID H+G C+A N+ G A + G
Sbjct: 554 ------LHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHG 588
Score = 35.8 bits (81), Expect = 0.035
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 22/139 (15%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD-----RLVNGM---LQC 111
L +T+ + + G Y+ L SN A F+V V P I D ++++G L C
Sbjct: 1217 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMC 1276
Query: 112 VAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGT 171
G P+P + W+ R A + D L V+Q+++ S+ G
Sbjct: 1277 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQ---------VLQANLSSA-----GH 1322
Query: 172 VECKAYNDVGKTSAYFNFA 190
C A N VG+ + +F +
Sbjct: 1323 YSCIAANAVGEKTKHFQLS 1341
Score = 35.8 bits (81), Expect = 0.035
Identities = 38/133 (28%), Positives = 52/133 (39%), Gaps = 23/133 (17%)
Query: 5 TVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTR 64
TV VN+ + LI E AFP P N T+ + S N + L +
Sbjct: 1361 TVTVNNP--ISLICEALAFPSP--------NITWMKDGAPFEASRNIQLLPGTHGLQILN 1410
Query: 65 LKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRL-----------VNGML--QC 111
+ + G YT +V+N A ++V V P I D L VN L +C
Sbjct: 1411 AQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLEC 1470
Query: 112 VAPGFPEPTIDWY 124
+ P PTI WY
Sbjct: 1471 ESWAVPPPTIRWY 1483
Score = 34.3 bits (77), Expect = 0.10
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 8/72 (11%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILT-----YDRLVNGM---LQC 111
L L+RL+ + GTYT + N+ A F V V P I + ++ G L C
Sbjct: 1989 LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 2048
Query: 112 VAPGFPEPTIDW 123
A G P P + W
Sbjct: 2049 EADGQPPPDVAW 2060
Score = 32.0 bits (71), Expect = 0.50
Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 20/130 (15%)
Query: 59 ELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI------LTYDRLVNGMLQCV 112
+L + + G Y + NS +A + V P I L+ + L C
Sbjct: 2810 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCK 2869
Query: 113 APGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTV 172
A G PEP I W PV + P G+L+V++ A GT
Sbjct: 2870 ARGSPEPNITW----------DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDA----GTY 2915
Query: 173 ECKAYNDVGK 182
C A N VG+
Sbjct: 2916 TCTAENAVGR 2925
Score = 30.8 bits (68), Expect = 1.1
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 9/74 (12%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEIL-TYDRLVN--------GMLQ 110
LH+ R + G Y+ + N A F + V PE++ D L N L
Sbjct: 1123 LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLL 1182
Query: 111 CVAPGFPEPTIDWY 124
C A G P P I W+
Sbjct: 1183 CEAMGIPPPAIRWF 1196
Score = 30.4 bits (67), Expect = 1.5
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 23/132 (17%)
Query: 5 TVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSE----L 60
T+ V +G L E P P+ IS + + P + +++VS L
Sbjct: 980 TLTVREGHPTSLSCECRGVPFPK----ISWRK------DGQPLPGEGAGLQHVSAVGRLL 1029
Query: 61 HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEIL------TYDRLVN---GMLQC 111
+L + + + GTYT SN N++ + V+ P+I T +V L+C
Sbjct: 1030 YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLEC 1089
Query: 112 VAPGFPEPTIDW 123
A G P PT+ W
Sbjct: 1090 NATGKPPPTVTW 1101
Score = 30.0 bits (66), Expect = 1.9
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI-----LTYDRLVNG--MLQCV 112
L + + + ++ G+Y + SN + + + + VN P I L LVN L C
Sbjct: 750 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCN 809
Query: 113 APGFPEPTIDW 123
A G P PT+ W
Sbjct: 810 ATGAPSPTLMW 820
Score = 29.6 bits (65), Expect = 2.5
Identities = 28/125 (22%), Positives = 47/125 (37%), Gaps = 15/125 (12%)
Query: 6 VFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRL 65
V V G+ L E +A P+P T+ + ++ +R L +
Sbjct: 1851 VLVRVGDKAVLSCETDALPEP--------TVTWYKDGQPLVLAQRTQALRGGQRLEIQEA 1902
Query: 66 KGTEGGTYTFLVSNSDVNAAIAFNVYVNT-----KPEILTYDRLVNG--MLQCVAPGFPE 118
+ ++ G Y+ VSN A F + V P+ T ++ +L C G P
Sbjct: 1903 QVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPA 1962
Query: 119 PTIDW 123
PT+ W
Sbjct: 1963 PTVTW 1967
Score = 29.3 bits (64), Expect = 3.3
Identities = 35/162 (21%), Positives = 57/162 (35%), Gaps = 26/162 (16%)
Query: 60 LHLTRLKGTEGGTYTFLVSN--SDVNAAIAFNVYV--NTKPEILTYDRLVNGM--LQCVA 113
L + ++ + G YT +N + +A V V N +P + L N L+C+A
Sbjct: 659 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLA 718
Query: 114 PGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVE 173
G P P + W+ + VD + L I+ + G+
Sbjct: 719 SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLR--------------IEQAQLSDAGSYR 764
Query: 174 CKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIV 215
C A N G T + + + P P L G V+V
Sbjct: 765 CVASNVAGSTELRYGL------RVNVPPRITLPPSLPGPVLV 800
Score = 28.9 bits (63), Expect = 4.3
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 12/93 (12%)
Query: 43 EDYPKSENE--SNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEIL- 99
ED P S + S ++ L + ++ G Y+ SN + + + V T P IL
Sbjct: 1596 EDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILG 1655
Query: 100 ---------TYDRLVNGMLQCVAPGFPEPTIDW 123
T + LQC A G P PTI W
Sbjct: 1656 DTEELVEEVTVNASSTVSLQCPALGNPVPTISW 1688
Score = 28.5 bits (62), Expect = 5.6
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 15/77 (19%)
Query: 109 LQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKH 168
L+C A G P PTI+W G R S ++TL P G L +++ A
Sbjct: 3137 LRCQATGEPTPTIEW-LQAGQPLRASRR-----LRTL-----PDGSLWLENVETGDA--- 3182
Query: 169 NGTVECKAYNDVGKTSA 185
GT +C A+N +G +A
Sbjct: 3183 -GTYDCVAHNLLGSATA 3198
Score = 28.1 bits (61), Expect = 7.3
Identities = 34/134 (25%), Positives = 53/134 (39%), Gaps = 28/134 (20%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI------LTYDRLVNGMLQCVA 113
L + + + G Y L SNS + ++ V P I LT +L C A
Sbjct: 2537 LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEA 2596
Query: 114 PGFPEPTIDWYFCPGTE-----QRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKH 168
G P+P + W+ G + Q+ + +LP + L + GP DS+ F
Sbjct: 2597 SGSPKPLVVWW-KDGQKLDFRLQQGAYRLLPSNALLLTAPGPQ----------DSAQF-- 2643
Query: 169 NGTVECKAYNDVGK 182
EC N+VG+
Sbjct: 2644 ----ECVVSNEVGE 2653
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 38.9 bits (89), Expect = 0.004
Identities = 33/128 (25%), Positives = 50/128 (39%), Gaps = 20/128 (15%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVN------GMLQCVA 113
L L L + G Y+ N+ + ++AF V ++T P I + VN +L C A
Sbjct: 3637 LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQA 3696
Query: 114 PGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVE 173
G P P + W +P+D ++ P G L +Q + A G
Sbjct: 3697 DGVPAPLVSW----------RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDA----GHYL 3742
Query: 174 CKAYNDVG 181
C A N G
Sbjct: 3743 CLASNSAG 3750
Score = 37.4 bits (85), Expect = 0.012
Identities = 36/153 (23%), Positives = 59/153 (38%), Gaps = 21/153 (13%)
Query: 35 NRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNT 94
N T+ W P S L ++ + T+GG Y + SN++ + + V
Sbjct: 547 NLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVRE 606
Query: 95 KPEILT------YDRLVNGMLQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSS 148
P++ + + V + C A G+P P I W ++ S + VD Q
Sbjct: 607 APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISW--SRESQALQEDSRIHVDAQ----- 659
Query: 149 GPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVG 181
G L++Q A G C+A N+VG
Sbjct: 660 ----GTLIIQGVAPEDA----GNYSCQATNEVG 684
Score = 37.0 bits (84), Expect = 0.016
Identities = 40/160 (25%), Positives = 63/160 (39%), Gaps = 28/160 (17%)
Query: 35 NRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNT 94
N T+ + +E + I+ EL + L+G + GTYT N+ A ++ +
Sbjct: 4068 NITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV 4127
Query: 95 KPEILTY---------DRLVNGMLQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTL 145
P T DRL L+C A G P P I W + + PV
Sbjct: 4128 LPVFTTLPGDRSLRLGDRL---WLRCAARGSPTPRIGW----------TVNDRPVTEGVS 4174
Query: 146 NSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSA 185
G G + ++++ + +GT C A N VG+T A
Sbjct: 4175 EQDG---GSTLQRAAVSR---EDSGTYVCWAENRVGRTQA 4208
Score = 36.2 bits (82), Expect = 0.027
Identities = 47/180 (26%), Positives = 68/180 (37%), Gaps = 31/180 (17%)
Query: 6 VFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRL 65
V V + V L+ E P P N T+ P S R +L L R
Sbjct: 1512 VAVMEDHLVQLLCEARGVPTP--------NITWFKDGALLPTSTKVVYTRGGRQLQLGRA 1563
Query: 66 KGTEGGTYTFLVSNS--DVNAAIAFNVYV-------NTKPEILTYDRLVNGMLQCVAPGF 116
+ ++ G YT SN+ A +VYV +P ++ L+CVA G
Sbjct: 1564 QSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGH 1623
Query: 117 PEPTIDWY-----FCPGTEQR--CSASVLPVDVQTLNSSG-------PPFGKLVVQSSID 162
P PT+ W+ E R SVL ++ SSG P G+ V+Q S++
Sbjct: 1624 PSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVE 1683
Score = 36.2 bits (82), Expect = 0.027
Identities = 41/161 (25%), Positives = 62/161 (38%), Gaps = 24/161 (14%)
Query: 43 EDYPKSE-NESNIRYV-SELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILT 100
E P +E NES + S L L G Y+ + S+ A + ++V V P++L
Sbjct: 1633 EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLV 1692
Query: 101 YDRL-----VNGM---LQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPF 152
+ L + G L C A G P PTI W R + + V V + ++
Sbjct: 1693 AEGLGQVTTIVGQPLELPCQASGSPVPTIQWL----QNGRPAEELAGVQVASQGTT---- 1744
Query: 153 GKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKG 193
ID H+G C+A N+ G A + G
Sbjct: 1745 ------LHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHG 1779
Score = 35.8 bits (81), Expect = 0.035
Identities = 51/193 (26%), Positives = 71/193 (36%), Gaps = 42/193 (21%)
Query: 5 TVFVNDGENVDL-IVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLT 63
TV V +G+ V L + P PE + W+ R P S + +IR LHL
Sbjct: 893 TVRVLEGQPVSLPCIVLAGRPLPE-RHWLKDGRPLP------PGSRH--SIRADGSLHLD 943
Query: 64 RLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI---LTYDRLVNGM---LQCVAPGFP 117
R G Y+ + +N+ + + V P I T+ G+ L CVA G P
Sbjct: 944 RALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVP 1003
Query: 118 EPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFG------KLVVQSSIDSSAFKHNGT 171
PTI W + L S GP + L+ Q S + G
Sbjct: 1004 APTITW---------------TKETNALTSRGPHYNVSKEGTLLIAQPSAQDA-----GA 1043
Query: 172 VECKAYNDVGKTS 184
C A N VG +S
Sbjct: 1044 YVCTATNTVGFSS 1056
Score = 35.8 bits (81), Expect = 0.035
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 22/139 (15%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD-----RLVNGM---LQC 111
L +T+ + + G Y+ L SN A F+V V P I D ++++G L C
Sbjct: 2408 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMC 2467
Query: 112 VAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGT 171
G P+P + W+ R A + D L V+Q+++ S+ G
Sbjct: 2468 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQ---------VLQANLSSA-----GH 2513
Query: 172 VECKAYNDVGKTSAYFNFA 190
C A N VG+ + +F +
Sbjct: 2514 YSCIAANAVGEKTKHFQLS 2532
Score = 35.8 bits (81), Expect = 0.035
Identities = 38/133 (28%), Positives = 52/133 (39%), Gaps = 23/133 (17%)
Query: 5 TVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTR 64
TV VN+ + LI E AFP P N T+ + S N + L +
Sbjct: 2552 TVTVNNP--ISLICEALAFPSP--------NITWMKDGAPFEASRNIQLLPGTHGLQILN 2601
Query: 65 LKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRL-----------VNGML--QC 111
+ + G YT +V+N A ++V V P I D L VN L +C
Sbjct: 2602 AQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLEC 2661
Query: 112 VAPGFPEPTIDWY 124
+ P PTI WY
Sbjct: 2662 ESWAVPPPTIRWY 2674
Score = 35.0 bits (79), Expect = 0.059
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 15/100 (15%)
Query: 32 ISLNRTFTDK--WEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFN 89
+S+NR K WE+Y + S L L +++ + G Y SN +A+ +
Sbjct: 1061 LSVNRLALSKYVWEEYGLLPSGS-------LRLAQVQVGDSGHYECTASNPAGSASHRYV 1113
Query: 90 VYVNTKPEILTYDRLVNGM------LQCVAPGFPEPTIDW 123
+ V P++ R++ + L CVA G PEP + W
Sbjct: 1114 LGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSW 1153
Score = 34.3 bits (77), Expect = 0.10
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 8/72 (11%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILT-----YDRLVNGM---LQC 111
L L+RL+ + GTYT + N+ A F V V P I + ++ G L C
Sbjct: 3180 LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 3239
Query: 112 VAPGFPEPTIDW 123
A G P P + W
Sbjct: 3240 EADGQPPPDVAW 3251
Score = 33.9 bits (76), Expect = 0.13
Identities = 31/128 (24%), Positives = 47/128 (36%), Gaps = 23/128 (17%)
Query: 69 EGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLV------NGMLQCVAPGFPEPTID 122
+ G Y+ +N +Y P + + +V +L C A G P P +
Sbjct: 671 DAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVI 730
Query: 123 WYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGK 182
WY G E L G GKL + ++ + A GT C+A N++G
Sbjct: 731 WY-RGGLE------------MILAPEGSSSGKLRIPAAQERDA----GTYTCRAVNELGD 773
Query: 183 TSAYFNFA 190
SA A
Sbjct: 774 ASAEIQLA 781
Score = 33.1 bits (74), Expect = 0.23
Identities = 32/128 (25%), Positives = 48/128 (37%), Gaps = 17/128 (13%)
Query: 2 INTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELH 61
+N V V GE L+ E P P W + E E S+ +L
Sbjct: 703 VNAVVLVAVGEEAVLVCEASGVPPPR-VIW------YRGGLEMILAPEGSSS----GKLR 751
Query: 62 LTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLV------NGMLQCVAPG 115
+ + + GTYT N +A+ + V P++ R V + +L C A G
Sbjct: 752 IPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATG 811
Query: 116 FPEPTIDW 123
P PT+ W
Sbjct: 812 RPPPTVTW 819
Score = 32.0 bits (71), Expect = 0.50
Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 20/130 (15%)
Query: 59 ELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI------LTYDRLVNGMLQCV 112
+L + + G Y + NS +A + V P I L+ + L C
Sbjct: 4001 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCK 4060
Query: 113 APGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTV 172
A G PEP I W PV + P G+L+V++ A GT
Sbjct: 4061 ARGSPEPNITW----------DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDA----GTY 4106
Query: 173 ECKAYNDVGK 182
C A N VG+
Sbjct: 4107 TCTAENAVGR 4116
Score = 31.6 bits (70), Expect = 0.66
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 8/72 (11%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD--RLVNGM------LQC 111
LH R++ + G Y+ N A F++ V T P +L + V G+ LQC
Sbjct: 1371 LHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQC 1430
Query: 112 VAPGFPEPTIDW 123
G P P ++W
Sbjct: 1431 WTSGVPTPQVEW 1442
Score = 30.8 bits (68), Expect = 1.1
Identities = 33/135 (24%), Positives = 51/135 (37%), Gaps = 25/135 (18%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPE--------ILTYDRLVNGMLQC 111
+H ++ ++ G Y SNS A + V P +L N L C
Sbjct: 1169 VHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPC 1228
Query: 112 VAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSS--IDSSAFKHN 169
A G P+P + W P +E G P ++ + S + S + +
Sbjct: 1229 PARGTPKPQVTWRKGPSSEP---------------LHGQPGVAVLEEGSLFLASVSPADS 1273
Query: 170 GTVECKAYNDVGKTS 184
G EC+A N+VG TS
Sbjct: 1274 GDYECQATNEVGSTS 1288
Score = 30.8 bits (68), Expect = 1.1
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 9/74 (12%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEIL-TYDRLVN--------GMLQ 110
LH+ R + G Y+ + N A F + V PE++ D L N L
Sbjct: 2314 LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLL 2373
Query: 111 CVAPGFPEPTIDWY 124
C A G P P I W+
Sbjct: 2374 CEAMGIPPPAIRWF 2387
Score = 30.4 bits (67), Expect = 1.5
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 23/132 (17%)
Query: 5 TVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSE----L 60
T+ V +G L E P P+ IS + + P + +++VS L
Sbjct: 2171 TLTVREGHPTSLSCECRGVPFPK----ISWRK------DGQPLPGEGAGLQHVSAVGRLL 2220
Query: 61 HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEIL------TYDRLVN---GMLQC 111
+L + + + GTYT SN N++ + V+ P+I T +V L+C
Sbjct: 2221 YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLEC 2280
Query: 112 VAPGFPEPTIDW 123
A G P PT+ W
Sbjct: 2281 NATGKPPPTVTW 2292
Score = 30.0 bits (66), Expect = 1.9
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI-----LTYDRLVNG--MLQCV 112
L + + + ++ G+Y + SN + + + + VN P I L LVN L C
Sbjct: 1941 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCN 2000
Query: 113 APGFPEPTIDW 123
A G P PT+ W
Sbjct: 2001 ATGAPSPTLMW 2011
Score = 29.6 bits (65), Expect = 2.5
Identities = 33/126 (26%), Positives = 44/126 (34%), Gaps = 25/126 (19%)
Query: 11 GENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSE---NESNIRYVSE--LHLTRL 65
GEN L PKP+ W P SE + + + E L L +
Sbjct: 1221 GENASLPCPARGTPKPQVT------------WRKGPSSEPLHGQPGVAVLEEGSLFLASV 1268
Query: 66 KGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVN--GM------LQCVAPGFP 117
+ G Y +N + + + V P I R N GM L+C A GFP
Sbjct: 1269 SPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFP 1328
Query: 118 EPTIDW 123
P I W
Sbjct: 1329 VPEIVW 1334
Score = 29.6 bits (65), Expect = 2.5
Identities = 28/125 (22%), Positives = 47/125 (37%), Gaps = 15/125 (12%)
Query: 6 VFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRL 65
V V G+ L E +A P+P T+ + ++ +R L +
Sbjct: 3042 VLVRVGDKAVLSCETDALPEP--------TVTWYKDGQPLVLAQRTQALRGGQRLEIQEA 3093
Query: 66 KGTEGGTYTFLVSNSDVNAAIAFNVYVNT-----KPEILTYDRLVNG--MLQCVAPGFPE 118
+ ++ G Y+ VSN A F + V P+ T ++ +L C G P
Sbjct: 3094 QVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPA 3153
Query: 119 PTIDW 123
PT+ W
Sbjct: 3154 PTVTW 3158
Score = 29.3 bits (64), Expect = 3.3
Identities = 35/162 (21%), Positives = 57/162 (35%), Gaps = 26/162 (16%)
Query: 60 LHLTRLKGTEGGTYTFLVSN--SDVNAAIAFNVYV--NTKPEILTYDRLVNGM--LQCVA 113
L + ++ + G YT +N + +A V V N +P + L N L+C+A
Sbjct: 1850 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLA 1909
Query: 114 PGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVE 173
G P P + W+ + VD + L I+ + G+
Sbjct: 1910 SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLR--------------IEQAQLSDAGSYR 1955
Query: 174 CKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIV 215
C A N G T + + + P P L G V+V
Sbjct: 1956 CVASNVAGSTELRYGL------RVNVPPRITLPPSLPGPVLV 1991
Score = 28.9 bits (63), Expect = 4.3
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 12/93 (12%)
Query: 43 EDYPKSENE--SNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEIL- 99
ED P S + S ++ L + ++ G Y+ SN + + + V T P IL
Sbjct: 2787 EDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILG 2846
Query: 100 ---------TYDRLVNGMLQCVAPGFPEPTIDW 123
T + LQC A G P PTI W
Sbjct: 2847 DTEELVEEVTVNASSTVSLQCPALGNPVPTISW 2879
Score = 28.5 bits (62), Expect = 5.6
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 15/77 (19%)
Query: 109 LQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKH 168
L+C A G P PTI+W G R S ++TL P G L +++ A
Sbjct: 4328 LRCQATGEPTPTIEW-LQAGQPLRASRR-----LRTL-----PDGSLWLENVETGDA--- 4373
Query: 169 NGTVECKAYNDVGKTSA 185
GT +C A+N +G +A
Sbjct: 4374 -GTYDCVAHNLLGSATA 4389
Score = 28.1 bits (61), Expect = 7.3
Identities = 34/134 (25%), Positives = 53/134 (39%), Gaps = 28/134 (20%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI------LTYDRLVNGMLQCVA 113
L + + + G Y L SNS + ++ V P I LT +L C A
Sbjct: 3728 LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEA 3787
Query: 114 PGFPEPTIDWYFCPGTE-----QRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKH 168
G P+P + W+ G + Q+ + +LP + L + GP DS+ F
Sbjct: 3788 SGSPKPLVVWW-KDGQKLDFRLQQGAYRLLPSNALLLTAPGPQ----------DSAQF-- 3834
Query: 169 NGTVECKAYNDVGK 182
EC N+VG+
Sbjct: 3835 ----ECVVSNEVGE 3844
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 38.9 bits (89), Expect = 0.004
Identities = 33/128 (25%), Positives = 50/128 (39%), Gaps = 20/128 (15%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVN------GMLQCVA 113
L L L + G Y+ N+ + ++AF V ++T P I + VN +L C A
Sbjct: 2355 LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQA 2414
Query: 114 PGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVE 173
G P P + W +P+D ++ P G L +Q + A G
Sbjct: 2415 DGVPAPLVSW----------RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDA----GHYL 2460
Query: 174 CKAYNDVG 181
C A N G
Sbjct: 2461 CLASNSAG 2468
Score = 37.0 bits (84), Expect = 0.016
Identities = 40/160 (25%), Positives = 63/160 (39%), Gaps = 28/160 (17%)
Query: 35 NRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNT 94
N T+ + +E + I+ EL + L+G + GTYT N+ A ++ +
Sbjct: 2786 NITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV 2845
Query: 95 KPEILTY---------DRLVNGMLQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTL 145
P T DRL L+C A G P P I W + + PV
Sbjct: 2846 LPVFTTLPGDRSLRLGDRL---WLRCAARGSPTPRIGW----------TVNDRPVTEGVS 2892
Query: 146 NSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSA 185
G G + ++++ + +GT C A N VG+T A
Sbjct: 2893 EQDG---GSTLQRAAVSR---EDSGTYVCWAENRVGRTQA 2926
Score = 36.2 bits (82), Expect = 0.027
Identities = 47/180 (26%), Positives = 68/180 (37%), Gaps = 31/180 (17%)
Query: 6 VFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRL 65
V V + V L+ E P P N T+ P S R +L L R
Sbjct: 230 VAVMEDHLVQLLCEARGVPTP--------NITWFKDGALLPTSTKVVYTRGGRQLQLGRA 281
Query: 66 KGTEGGTYTFLVSNS--DVNAAIAFNVYV-------NTKPEILTYDRLVNGMLQCVAPGF 116
+ ++ G YT SN+ A +VYV +P ++ L+CVA G
Sbjct: 282 QSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGH 341
Query: 117 PEPTIDWY-----FCPGTEQR--CSASVLPVDVQTLNSSG-------PPFGKLVVQSSID 162
P PT+ W+ E R SVL ++ SSG P G+ V+Q S++
Sbjct: 342 PSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVE 401
Score = 36.2 bits (82), Expect = 0.027
Identities = 41/161 (25%), Positives = 62/161 (38%), Gaps = 24/161 (14%)
Query: 43 EDYPKSE-NESNIRYV-SELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILT 100
E P +E NES + S L L G Y+ + S+ A + ++V V P++L
Sbjct: 351 EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLV 410
Query: 101 YDRL-----VNGM---LQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPF 152
+ L + G L C A G P PTI W R + + V V + ++
Sbjct: 411 AEGLGQVTTIVGQPLELPCQASGSPVPTIQWL----QNGRPAEELAGVQVASQGTT---- 462
Query: 153 GKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKG 193
ID H+G C+A N+ G A + G
Sbjct: 463 ------LHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHG 497
Score = 35.8 bits (81), Expect = 0.035
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 22/139 (15%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD-----RLVNGM---LQC 111
L +T+ + + G Y+ L SN A F+V V P I D ++++G L C
Sbjct: 1126 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMC 1185
Query: 112 VAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGT 171
G P+P + W+ R A + D L V+Q+++ S+ G
Sbjct: 1186 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQ---------VLQANLSSA-----GH 1231
Query: 172 VECKAYNDVGKTSAYFNFA 190
C A N VG+ + +F +
Sbjct: 1232 YSCIAANAVGEKTKHFQLS 1250
Score = 35.8 bits (81), Expect = 0.035
Identities = 38/133 (28%), Positives = 52/133 (39%), Gaps = 23/133 (17%)
Query: 5 TVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTR 64
TV VN+ + LI E AFP P N T+ + S N + L +
Sbjct: 1270 TVTVNNP--ISLICEALAFPSP--------NITWMKDGAPFEASRNIQLLPGTHGLQILN 1319
Query: 65 LKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRL-----------VNGML--QC 111
+ + G YT +V+N A ++V V P I D L VN L +C
Sbjct: 1320 AQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLEC 1379
Query: 112 VAPGFPEPTIDWY 124
+ P PTI WY
Sbjct: 1380 ESWAVPPPTIRWY 1392
Score = 34.3 bits (77), Expect = 0.10
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 8/72 (11%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILT-----YDRLVNGM---LQC 111
L L+RL+ + GTYT + N+ A F V V P I + ++ G L C
Sbjct: 1898 LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 1957
Query: 112 VAPGFPEPTIDW 123
A G P P + W
Sbjct: 1958 EADGQPPPDVAW 1969
Score = 32.0 bits (71), Expect = 0.50
Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 20/130 (15%)
Query: 59 ELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI------LTYDRLVNGMLQCV 112
+L + + G Y + NS +A + V P I L+ + L C
Sbjct: 2719 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCK 2778
Query: 113 APGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTV 172
A G PEP I W PV + P G+L+V++ A GT
Sbjct: 2779 ARGSPEPNITW----------DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDA----GTY 2824
Query: 173 ECKAYNDVGK 182
C A N VG+
Sbjct: 2825 TCTAENAVGR 2834
Score = 31.6 bits (70), Expect = 0.66
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 8/72 (11%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD--RLVNGM------LQC 111
LH R++ + G Y+ N A F++ V T P +L + V G+ LQC
Sbjct: 89 LHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQC 148
Query: 112 VAPGFPEPTIDW 123
G P P ++W
Sbjct: 149 WTSGVPTPQVEW 160
Score = 30.8 bits (68), Expect = 1.1
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 9/74 (12%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEIL-TYDRLVN--------GMLQ 110
LH+ R + G Y+ + N A F + V PE++ D L N L
Sbjct: 1032 LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLL 1091
Query: 111 CVAPGFPEPTIDWY 124
C A G P P I W+
Sbjct: 1092 CEAMGIPPPAIRWF 1105
Score = 30.0 bits (66), Expect = 1.9
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI-----LTYDRLVNG--MLQCV 112
L + + + ++ G+Y + SN + + + + VN P I L LVN L C
Sbjct: 659 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCN 718
Query: 113 APGFPEPTIDW 123
A G P PT+ W
Sbjct: 719 ATGAPSPTLMW 729
Score = 29.6 bits (65), Expect = 2.5
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 23/132 (17%)
Query: 5 TVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSE----L 60
T+ V +G L E P P+ IS + + P + +++VS L
Sbjct: 889 TLTVREGHPTRLSCECRGVPFPK----ISWRK------DGQPLPGEGAGLQHVSAVGRLL 938
Query: 61 HLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEIL------TYDRLVN---GMLQC 111
+L + + + GTYT SN N++ + V+ P+I T +V L+C
Sbjct: 939 YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLEC 998
Query: 112 VAPGFPEPTIDW 123
A G P PT+ W
Sbjct: 999 NATGKPPPTVTW 1010
Score = 29.6 bits (65), Expect = 2.5
Identities = 28/125 (22%), Positives = 47/125 (37%), Gaps = 15/125 (12%)
Query: 6 VFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLTRL 65
V V G+ L E +A P+P T+ + ++ +R L +
Sbjct: 1760 VLVRVGDKAVLSCETDALPEP--------TVTWYKDGQPLVLAQRTQALRGGQRLEIQEA 1811
Query: 66 KGTEGGTYTFLVSNSDVNAAIAFNVYVNT-----KPEILTYDRLVNG--MLQCVAPGFPE 118
+ ++ G Y+ VSN A F + V P+ T ++ +L C G P
Sbjct: 1812 QVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPA 1871
Query: 119 PTIDW 123
PT+ W
Sbjct: 1872 PTVTW 1876
Score = 29.3 bits (64), Expect = 3.3
Identities = 35/162 (21%), Positives = 57/162 (35%), Gaps = 26/162 (16%)
Query: 60 LHLTRLKGTEGGTYTFLVSN--SDVNAAIAFNVYV--NTKPEILTYDRLVNGM--LQCVA 113
L + ++ + G YT +N + +A V V N +P + L N L+C+A
Sbjct: 568 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLA 627
Query: 114 PGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVE 173
G P P + W+ + VD + L I+ + G+
Sbjct: 628 SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLR--------------IEQAQLSDAGSYR 673
Query: 174 CKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIV 215
C A N G T + + + P P L G V+V
Sbjct: 674 CVASNVAGSTELRYGL------RVNVPPRITLPPSLPGPVLV 709
Score = 28.9 bits (63), Expect = 4.3
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 12/93 (12%)
Query: 43 EDYPKSENE--SNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEIL- 99
ED P S + S ++ L + ++ G Y+ SN + + + V T P IL
Sbjct: 1505 EDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILG 1564
Query: 100 ---------TYDRLVNGMLQCVAPGFPEPTIDW 123
T + LQC A G P PTI W
Sbjct: 1565 DTEELVEEVTVNASSTVSLQCPALGNPVPTISW 1597
Score = 28.9 bits (63), Expect = 4.3
Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 27/135 (20%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYV---------NTKPEILTYDRLVNGMLQ 110
L + R + + G Y L N +A V + +P+ +T + L+
Sbjct: 2991 LTIRRTERDDAGRYQCLAENE---MGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALR 3047
Query: 111 CVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNG 170
C A G P PTI+W G R S ++TL P G L +++ A G
Sbjct: 3048 CQATGEPTPTIEW-LQAGQPLRASRR-----LRTL-----PDGSLWLENVETGDA----G 3092
Query: 171 TVECKAYNDVGKTSA 185
T +C A+N +G +A
Sbjct: 3093 TYDCVAHNLLGSATA 3107
Score = 28.1 bits (61), Expect = 7.3
Identities = 34/134 (25%), Positives = 53/134 (39%), Gaps = 28/134 (20%)
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI------LTYDRLVNGMLQCVA 113
L + + + G Y L SNS + ++ V P I LT +L C A
Sbjct: 2446 LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEA 2505
Query: 114 PGFPEPTIDWYFCPGTE-----QRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKH 168
G P+P + W+ G + Q+ + +LP + L + GP DS+ F
Sbjct: 2506 SGSPKPLVVWW-KDGQKLDFRLQQGAYRLLPSNALLLTAPGPQ----------DSAQF-- 2552
Query: 169 NGTVECKAYNDVGK 182
EC N+VG+
Sbjct: 2553 ----ECVVSNEVGE 2562
>gi|22902128 PTK7 protein tyrosine kinase 7 isoform c precursor
[Homo sapiens]
Length = 940
Score = 38.9 bits (89), Expect = 0.004
Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 7/71 (9%)
Query: 60 LHLTRLKGTEGGTYTFLVSN-------SDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCV 112
LH R+ + G YT + SN + V +A + +PE T + +LQC
Sbjct: 425 LHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCE 484
Query: 113 APGFPEPTIDW 123
A G P+P I W
Sbjct: 485 AQGDPKPLIQW 495
>gi|22902126 PTK7 protein tyrosine kinase 7 isoform b precursor
[Homo sapiens]
Length = 1030
Score = 38.9 bits (89), Expect = 0.004
Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 7/71 (9%)
Query: 60 LHLTRLKGTEGGTYTFLVSN-------SDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCV 112
LH R+ + G YT + SN + V +A + +PE T + +LQC
Sbjct: 515 LHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCE 574
Query: 113 APGFPEPTIDW 123
A G P+P I W
Sbjct: 575 AQGDPKPLIQW 585
Score = 33.9 bits (76), Expect = 0.13
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 59 ELHLTRLKGTEGGTYTFLVSN------SDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCV 112
EL L + ++ G YT +N DVN +A KP+ + G L C+
Sbjct: 375 ELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCL 434
Query: 113 APGFPEPTIDWY 124
P+PT+ WY
Sbjct: 435 TQATPKPTVVWY 446
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 38.5 bits (88), Expect = 0.005
Identities = 55/209 (26%), Positives = 77/209 (36%), Gaps = 44/209 (21%)
Query: 5 TVFVNDGENVDL-IVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELHLT 63
TV V +G+ V L + P PE + W+ R P S + +IR LHL
Sbjct: 776 TVRVLEGQPVSLPCIVLAGRPLPE-RHWLKDGRPLP------PGSRH--SIRADGSLHLD 826
Query: 64 RLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI---LTYDRLVNGM---LQCVAPGFP 117
R G Y+ + +N+ + + V P I T+ G+ L CVA G P
Sbjct: 827 RALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVP 886
Query: 118 EPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFG------KLVVQSSIDSSAFKHNGT 171
PTI W + L S GP + L+ Q S + G
Sbjct: 887 APTITW---------------TKETNALTSRGPHYNVSKEGTLLIAQPSAQDA-----GA 926
Query: 172 VECKAYNDVGKTSAYFNFAFKGNNKEQIH 200
C A N VG +S + N K +IH
Sbjct: 927 YVCTATNTVGFSSQEMRLSV--NTKPRIH 953
Score = 37.4 bits (85), Expect = 0.012
Identities = 36/153 (23%), Positives = 59/153 (38%), Gaps = 21/153 (13%)
Query: 35 NRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNT 94
N T+ W P S L ++ + T+GG Y + SN++ + + V
Sbjct: 430 NLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVRE 489
Query: 95 KPEILT------YDRLVNGMLQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSS 148
P++ + + V + C A G+P P I W ++ S + VD Q
Sbjct: 490 APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISW--SRESQALQEDSRIHVDAQ----- 542
Query: 149 GPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVG 181
G L++Q A G C+A N+VG
Sbjct: 543 ----GTLIIQGVAPEDA----GNYSCQATNEVG 567
Score = 33.9 bits (76), Expect = 0.13
Identities = 31/128 (24%), Positives = 47/128 (36%), Gaps = 23/128 (17%)
Query: 69 EGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLV------NGMLQCVAPGFPEPTID 122
+ G Y+ +N +Y P + + +V +L C A G P P +
Sbjct: 554 DAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVI 613
Query: 123 WYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGK 182
WY G E L G GKL + ++ + A GT C+A N++G
Sbjct: 614 WY-RGGLE------------MILAPEGSSSGKLRIPAAQERDA----GTYTCRAVNELGD 656
Query: 183 TSAYFNFA 190
SA A
Sbjct: 657 ASAEIQLA 664
Score = 33.1 bits (74), Expect = 0.23
Identities = 32/128 (25%), Positives = 48/128 (37%), Gaps = 17/128 (13%)
Query: 2 INTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELH 61
+N V V GE L+ E P P W + E E S+ +L
Sbjct: 586 VNAVVLVAVGEEAVLVCEASGVPPPR-VIW------YRGGLEMILAPEGSSS----GKLR 634
Query: 62 LTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLV------NGMLQCVAPG 115
+ + + GTYT N +A+ + V P++ R V + +L C A G
Sbjct: 635 IPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATG 694
Query: 116 FPEPTIDW 123
P PT+ W
Sbjct: 695 RPPPTVTW 702
Score = 30.0 bits (66), Expect = 1.9
Identities = 41/169 (24%), Positives = 58/169 (34%), Gaps = 31/169 (18%)
Query: 53 NIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI-LTYDRLVNGMLQ- 110
N+ L + + + G Y +N+ ++ + VNTKP I + R N LQ
Sbjct: 907 NVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQV 966
Query: 111 -----------CVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKL-VVQ 158
C A G P P + W + PV T P G L + Q
Sbjct: 967 TAKAGEEVTLDCEAKGSPPPLVTW----------TKDSRPVPPITNRYGLLPSGSLRLAQ 1016
Query: 159 SSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTP 207
+ S G EC A N G S + +G Q P +L P
Sbjct: 1017 VQVGDS-----GHYECTASNPAGSASHRYVLGVQGRTSWQ--PQSLPVP 1058
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 38.5 bits (88), Expect = 0.005
Identities = 51/225 (22%), Positives = 87/225 (38%), Gaps = 62/225 (27%)
Query: 4 TTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSE---- 59
+ V V +G+ V L+ P H I + F + +P E + R++S+
Sbjct: 203 SAVSVREGQGVVLMCS-----PPPHSPEIIYSWVFNE----FPSFVAEDSRRFISQETGN 253
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAF----------NVYVNTKPEI-------LTYD 102
L++++++ ++ G+Y LV N+ NA + V +P+I +T
Sbjct: 254 LYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAA 313
Query: 103 RLVNGMLQCVAPGFPEPTIDW-----YFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVV 157
+ ++C A G P PTI W Y R S +VL + L+ +
Sbjct: 314 KGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDA--------- 364
Query: 158 QSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPH 202
G EC+A N GK S F+G + +PH
Sbjct: 365 ------------GIYECRAENSRGKNS------FRGQLQVYTYPH 391
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 38.5 bits (88), Expect = 0.005
Identities = 51/225 (22%), Positives = 87/225 (38%), Gaps = 62/225 (27%)
Query: 4 TTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSE---- 59
+ V V +G+ V L+ P H I + F + +P E + R++S+
Sbjct: 129 SAVSVREGQGVVLMCS-----PPPHSPEIIYSWVFNE----FPSFVAEDSRRFISQETGN 179
Query: 60 LHLTRLKGTEGGTYTFLVSNSDVNAAIAF----------NVYVNTKPEI-------LTYD 102
L++++++ ++ G+Y LV N+ NA + V +P+I +T
Sbjct: 180 LYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAA 239
Query: 103 RLVNGMLQCVAPGFPEPTIDW-----YFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVV 157
+ ++C A G P PTI W Y R S +VL + L+ +
Sbjct: 240 KGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDA--------- 290
Query: 158 QSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPH 202
G EC+A N GK S F+G + +PH
Sbjct: 291 ------------GIYECRAENSRGKNS------FRGQLQVYTYPH 317
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 38.1 bits (87), Expect = 0.007
Identities = 47/201 (23%), Positives = 81/201 (40%), Gaps = 42/201 (20%)
Query: 1 MINTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRY---V 57
++N T N G++V L+ + E FP+P ++T E + E++ +
Sbjct: 220 IVNATA--NLGQSVTLVCDAEGFPEP--------TMSWTKDGEQIEQEEDDEKYIFSDDS 269
Query: 58 SELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGM-------LQ 110
S+L + ++ + Y + N ++ V KP+I TY M L
Sbjct: 270 SQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKI-TYVENQTAMELEEQVTLT 328
Query: 111 CVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQS-------SIDS 163
C A G P P+I W R S + + +TL+ G +VV+S ++ S
Sbjct: 329 CEASGDPIPSITW--------RTSTRNISSEEKTLD------GHMVVRSHARVSSLTLKS 374
Query: 164 SAFKHNGTVECKAYNDVGKTS 184
+ G C A N +G+ S
Sbjct: 375 IQYTDAGEYICTASNTIGQDS 395
Score = 35.8 bits (81), Expect = 0.035
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 12/75 (16%)
Query: 60 LHLTRLKGTEGGTYTF---LVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGM-------- 108
L + +K T+ GTY +++ ++N V VN P I +VN
Sbjct: 174 LQIRGIKKTDEGTYRCEGRILARGEINFK-DIQVIVNVPPTIQARQNIVNATANLGQSVT 232
Query: 109 LQCVAPGFPEPTIDW 123
L C A GFPEPT+ W
Sbjct: 233 LVCDAEGFPEPTMSW 247
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 38.1 bits (87), Expect = 0.007
Identities = 47/201 (23%), Positives = 81/201 (40%), Gaps = 42/201 (20%)
Query: 1 MINTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRY---V 57
++N T N G++V L+ + E FP+P ++T E + E++ +
Sbjct: 220 IVNATA--NLGQSVTLVCDAEGFPEP--------TMSWTKDGEQIEQEEDDEKYIFSDDS 269
Query: 58 SELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGM-------LQ 110
S+L + ++ + Y + N ++ V KP+I TY M L
Sbjct: 270 SQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKI-TYVENQTAMELEEQVTLT 328
Query: 111 CVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQS-------SIDS 163
C A G P P+I W R S + + +TL+ G +VV+S ++ S
Sbjct: 329 CEASGDPIPSITW--------RTSTRNISSEEKTLD------GHMVVRSHARVSSLTLKS 374
Query: 164 SAFKHNGTVECKAYNDVGKTS 184
+ G C A N +G+ S
Sbjct: 375 IQYTDAGEYICTASNTIGQDS 395
Score = 35.8 bits (81), Expect = 0.035
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 12/75 (16%)
Query: 60 LHLTRLKGTEGGTYTF---LVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGM-------- 108
L + +K T+ GTY +++ ++N V VN P I +VN
Sbjct: 174 LQIRGIKKTDEGTYRCEGRILARGEINFK-DIQVIVNVPPTIQARQNIVNATANLGQSVT 232
Query: 109 LQCVAPGFPEPTIDW 123
L C A GFPEPT+ W
Sbjct: 233 LVCDAEGFPEPTMSW 247
>gi|66346706 neuronal growth regulator 1 [Homo sapiens]
Length = 354
Score = 38.1 bits (87), Expect = 0.007
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Query: 40 DKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI- 98
DKW P+ + + L + + T+ G YT V + ++ V P+I
Sbjct: 83 DKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIY 142
Query: 99 -----LTYDRLVNGMLQCVAPGFPEPTIDW 123
+T + N L C+A G PEP+I W
Sbjct: 143 DISNDMTVNEGTNVTLTCLATGKPEPSISW 172
Score = 30.4 bits (67), Expect = 1.5
Identities = 43/193 (22%), Positives = 72/193 (37%), Gaps = 37/193 (19%)
Query: 2 INTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELH 61
I+ + VN+G NV L P+P W ++ P ++ N +Y+
Sbjct: 144 ISNDMTVNEGTNVTLTCLATGKPEPSIS-WRHIS----------PSAKPFENGQYLDIYG 192
Query: 62 LTRLKGTEGGTYTFLVSNS----DVNAAIAFNVYVNTKPEIL-----TYDRLVNGMLQCV 112
+TR + G Y N DV V VN P I T +G+++C
Sbjct: 193 ITR---DQAGEYECSAENDVSFPDVRKV---KVVVNFAPTIQEIKSGTVTPGRSGLIRCE 246
Query: 113 APGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTV 172
G P P +WY E++ + +Q ++ ++ + +H G
Sbjct: 247 GAGVPPPAFEWY---KGEKKLFNGQQGIIIQNFSTRS--------ILTVTNVTQEHFGNY 295
Query: 173 ECKAYNDVGKTSA 185
C A N +G T+A
Sbjct: 296 TCVAANKLGTTNA 308
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 37.4 bits (85), Expect = 0.012
Identities = 36/153 (23%), Positives = 59/153 (38%), Gaps = 21/153 (13%)
Query: 35 NRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNT 94
N T+ W P S L ++ + T+GG Y + SN++ + + V
Sbjct: 546 NLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVRE 605
Query: 95 KPEILT------YDRLVNGMLQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSS 148
P++ + + V + C A G+P P I W ++ S + VD Q
Sbjct: 606 APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISW--SRESQALQEDSRIHVDAQ----- 658
Query: 149 GPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVG 181
G L++Q A G C+A N+VG
Sbjct: 659 ----GTLIIQGVAPEDA----GNYSCQATNEVG 683
Score = 33.9 bits (76), Expect = 0.13
Identities = 31/128 (24%), Positives = 47/128 (36%), Gaps = 23/128 (17%)
Query: 69 EGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLV------NGMLQCVAPGFPEPTID 122
+ G Y+ +N +Y P + + +V +L C A G P P +
Sbjct: 670 DAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVI 729
Query: 123 WYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGK 182
WY G E L G GKL + ++ + A GT C+A N++G
Sbjct: 730 WY-RGGLE------------MILAPEGSSSGKLRIPAAQERDA----GTYTCRAVNELGD 772
Query: 183 TSAYFNFA 190
SA A
Sbjct: 773 ASAEIQLA 780
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 37.4 bits (85), Expect = 0.012
Identities = 56/231 (24%), Positives = 88/231 (38%), Gaps = 42/231 (18%)
Query: 2 INTTVFVNDGENVDLIVEYEAFPKPEHQQWISLNRTFTDKWEDYPKSENESNIRYVSELH 61
I++ V VN+G NV L+ P+P W L T E E Y+ L
Sbjct: 137 ISSDVTVNEGSNVTLVCMANGRPEPV-ITWRHLTPT---------GREFEGEEEYLEILG 186
Query: 62 LTRLKGTEGGTYTFLVSNSDVNAAI-AFNVYVNTKPEI-------LTYDRLVNGMLQCVA 113
+TR + G Y +N +A + V VN P I T R L+C A
Sbjct: 187 ITR---EQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGR--QASLKCEA 241
Query: 114 PGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSS--IDSSAFKHNGT 171
P P +WY D + +++G QSS + + +H G
Sbjct: 242 SAVPAPDFEWY--------------RDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGN 287
Query: 172 VECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCII 222
C A N +G T+A G+ + +L PL +++ A ++C++
Sbjct: 288 YTCVAANKLGVTNASLVLFRPGSVRGINGSISLAVPL---WLLAASLLCLL 335
Score = 35.8 bits (81), Expect = 0.035
Identities = 36/147 (24%), Positives = 52/147 (35%), Gaps = 25/147 (17%)
Query: 40 DKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI- 98
DKW P+ E E L + ++ + G+YT V + V P+I
Sbjct: 76 DKWSLDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKIS 135
Query: 99 -----LTYDRLVNGMLQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFG 153
+T + N L C+A G PEP I W + L +G F
Sbjct: 136 NISSDVTVNEGSNVTLVCMANGRPEPVITW-------------------RHLTPTGREFE 176
Query: 154 KLVVQSSIDSSAFKHNGTVECKAYNDV 180
I + +G ECKA N+V
Sbjct: 177 GEEEYLEILGITREQSGKYECKAANEV 203
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,931,081
Number of Sequences: 37866
Number of extensions: 443420
Number of successful extensions: 1734
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 1176
Number of HSP's gapped (non-prelim): 607
length of query: 245
length of database: 18,247,518
effective HSP length: 100
effective length of query: 145
effective length of database: 14,460,918
effective search space: 2096833110
effective search space used: 2096833110
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.