Guide to the Human Genome
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Search of human proteins with 169217962

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169217962 PREDICTED: similar to phosphodiesterase 4D
interacting protein [Homo sapiens]
         (424 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169217962 PREDICTED: similar to phosphodiesterase 4D interact...   830   0.0  
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...   825   0.0  
gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6...    56   5e-08
gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami...    56   5e-08
gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami...    56   5e-08
gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6...    56   5e-08
gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2...    48   2e-05
gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1...    48   2e-05
gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap...    48   2e-05
gi|42794779 myosin 18A isoform b [Homo sapiens]                        46   6e-05
gi|28416946 myosin 18A isoform a [Homo sapiens]                        46   6e-05
gi|154277118 spectrin repeat containing, nuclear envelope 1 isof...    46   7e-05
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    46   7e-05
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    46   7e-05
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    45   1e-04
gi|92110019 hypothetical protein LOC55672 [Homo sapiens]               45   1e-04
gi|28269672 serologically defined colon cancer antigen 8 [Homo s...    45   2e-04
gi|157042792 coiled-coil domain containing 64B [Homo sapiens]          44   2e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             43   5e-04
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     43   5e-04
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    42   0.001
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       41   0.002
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       41   0.002
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        41   0.002
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        41   0.002
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    41   0.002
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     41   0.002
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]          40   0.004
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         40   0.004
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         40   0.004

>gi|169217962 PREDICTED: similar to phosphodiesterase 4D interacting
           protein [Homo sapiens]
          Length = 424

 Score =  830 bits (2144), Expect = 0.0
 Identities = 424/424 (100%), Positives = 424/424 (100%)

Query: 1   MLSLCLENAELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGK 60
           MLSLCLENAELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGK
Sbjct: 1   MLSLCLENAELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGK 60

Query: 61  LKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNV 120
           LKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNV
Sbjct: 61  LKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNV 120

Query: 121 TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ 180
           TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ
Sbjct: 121 TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ 180

Query: 181 DLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAE 240
           DLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAE
Sbjct: 181 DLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAE 240

Query: 241 REETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKS 300
           REETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKS
Sbjct: 241 REETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKS 300

Query: 301 ENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSS 360
           ENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSS
Sbjct: 301 ENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSS 360

Query: 361 PHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSA 420
           PHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSA
Sbjct: 361 PHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSA 420

Query: 421 SWPG 424
           SWPG
Sbjct: 421 SWPG 424


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score =  825 bits (2131), Expect = 0.0
 Identities = 422/424 (99%), Positives = 422/424 (99%)

Query: 1    MLSLCLENAELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGK 60
            MLSLCLENAELKEQMGE MSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGK
Sbjct: 1049 MLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGK 1108

Query: 61   LKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNV 120
            LKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNV
Sbjct: 1109 LKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNV 1168

Query: 121  TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ 180
            TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ
Sbjct: 1169 TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ 1228

Query: 181  DLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAE 240
            DLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAE
Sbjct: 1229 DLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAE 1288

Query: 241  REETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKS 300
            REETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKS
Sbjct: 1289 REETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKS 1348

Query: 301  ENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSS 360
            ENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERP KLRAVGTLEGSS
Sbjct: 1349 ENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPWKLRAVGTLEGSS 1408

Query: 361  PHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSA 420
            PHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSA
Sbjct: 1409 PHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSA 1468

Query: 421  SWPG 424
            SWPG
Sbjct: 1469 SWPG 1472


>gi|239752894 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 298

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 24/51 (47%), Positives = 37/51 (72%)

Query: 154 GPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYR 204
           GP++  S+  + Q+LRS+L +CKQ +QDL EK L S+AT ++  N L+KY+
Sbjct: 10  GPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60


>gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 24/51 (47%), Positives = 37/51 (72%)

Query: 154 GPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYR 204
           GP++  S+  + Q+LRS+L +CKQ +QDL EK L S+AT ++  N L+KY+
Sbjct: 10  GPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60


>gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 24/51 (47%), Positives = 37/51 (72%)

Query: 154 GPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYR 204
           GP++  S+  + Q+LRS+L +CKQ +QDL EK L S+AT ++  N L+KY+
Sbjct: 10  GPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60


>gi|239741281 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 322

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 24/51 (47%), Positives = 37/51 (72%)

Query: 154 GPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYR 204
           GP++  S+  + Q+LRS+L +CKQ +QDL EK L S+AT ++  N L+KY+
Sbjct: 10  GPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60


>gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2
           [Homo sapiens]
          Length = 638

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 52/205 (25%), Positives = 91/205 (44%), Gaps = 29/205 (14%)

Query: 166 QHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQ 225
           Q LRSQL++  Q+++DL+EK L+++AT ++ AN+L+KY+         ++    I   L+
Sbjct: 22  QELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK--------CEEYKDIIDSVLR 73

Query: 226 DLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLE 285
           D        +E   + EE    +   H+  KE+  +     E+ R G   AS    K L+
Sbjct: 74  DELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLR----EKLREGRD-ASRWLNKHLK 128

Query: 286 NQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLE 345
             L   +  +  G            +DL+ QL   +++ ++L   V  LS  +D     +
Sbjct: 129 TLLTPDDPDKSQG------------QDLREQLAEGHRLAEHL---VHKLSPENDEDEDED 173

Query: 346 RPRKLRAVGTL-EGSSPHSVPDEDE 369
              K   V  + E  +P  V   +E
Sbjct: 174 EDDKDEEVEKVQESPAPREVQKTEE 198


>gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1
           [Homo sapiens]
          Length = 667

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 52/205 (25%), Positives = 91/205 (44%), Gaps = 29/205 (14%)

Query: 166 QHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQ 225
           Q LRSQL++  Q+++DL+EK L+++AT ++ AN+L+KY+         ++    I   L+
Sbjct: 22  QELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK--------CEEYKDIIDSVLR 73

Query: 226 DLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLE 285
           D        +E   + EE    +   H+  KE+  +     E+ R G   AS    K L+
Sbjct: 74  DELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLR----EKLREGRD-ASRWLNKHLK 128

Query: 286 NQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLE 345
             L   +  +  G            +DL+ QL   +++ ++L   V  LS  +D     +
Sbjct: 129 TLLTPDDPDKSQG------------QDLREQLAEGHRLAEHL---VHKLSPENDEDEDED 173

Query: 346 RPRKLRAVGTL-EGSSPHSVPDEDE 369
              K   V  + E  +P  V   +E
Sbjct: 174 EDDKDEEVEKVQESPAPREVQKTEE 198


>gi|221218991 neuroblastoma breakpoint family, member 4 [Homo
           sapiens]
          Length = 638

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 52/205 (25%), Positives = 91/205 (44%), Gaps = 29/205 (14%)

Query: 166 QHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQ 225
           Q LRSQL++  Q+++DL+EK L+++AT ++ AN+L+KY+         ++    I   L+
Sbjct: 22  QELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK--------CEEYKDIIDSVLR 73

Query: 226 DLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLE 285
           D        +E   + EE    +   H+  KE+  +     E+ R G   AS    K L+
Sbjct: 74  DELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLR----EKLREGRD-ASRWLNKHLK 128

Query: 286 NQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLE 345
             L   +  +  G            +DL+ QL   +++ ++L   V  LS  +D     +
Sbjct: 129 TLLTPDDPDKSQG------------QDLREQLAEGHRLAEHL---VHKLSPENDEDEDED 173

Query: 346 RPRKLRAVGTL-EGSSPHSVPDEDE 369
              K   V  + E  +P  V   +E
Sbjct: 174 EDDKDEEVEKVQESPAPREVQKTEE 198


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 87/416 (20%), Positives = 163/416 (39%), Gaps = 48/416 (11%)

Query: 24   EIEEDKEKGE--VMVETVVTKEGLSESSLQAEFR-KLQGKLKNAHNIINLL--------- 71
            E+++D   GE  +  E  V +   ++  LQ EF  KL+ + +N   +   L         
Sbjct: 1361 EVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEE 1420

Query: 72   KEQLVLSSKEGNSKLTPELL---VHLTSTIERINTELVGSPGK--------HQHQEEGNV 120
             ++ +   K+   +LT EL    +HL     R N EL     +        H+  +   +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVR-NHELEKKQRRFDSELSQAHEEAQREKL 1479

Query: 121  TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ 180
                  R + + L   F++   QL+ +        Q   SL    Q + SQ S+ +    
Sbjct: 1480 QREKLQREKDMLLAEAFSLK-QQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538

Query: 181  DLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAE 240
             ++++L   EA V  Q  EL++    +    +++Q   +++++++ +        E+  E
Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTI---QMLEQAKLRLEMEMERMRQTHSKEMESRDE 1595

Query: 241  REETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKS 300
              E     C++     E+ L E    +Q           E++ LE +L    +       
Sbjct: 1596 EVEEARQSCQKKLKQMEVQLEEEYEDKQ-------KVLREKRELEGKLATLSDQVNRRDF 1648

Query: 301  ENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSS 360
            E+   LRKD+K  KA L +A  ++ +LK+   S    +   + LE   +      ++   
Sbjct: 1649 ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEE-SEFTCAAAVKARK 1707

Query: 361  PHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEE 416
               V  ED     D          +AK  LE  + R+     Q  KN ++ +L E+
Sbjct: 1708 AMEVEIEDLHLQIDDIA-------KAKTALEEQLSRL-----QREKNEIQNRLEED 1751



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 70/343 (20%), Positives = 136/343 (39%), Gaps = 45/343 (13%)

Query: 4    LCLENAELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSL---QAEFRKLQGK 60
            L  E   LK+Q+ E   D     +     E  ++ + ++E   E+SL   + + R L+ K
Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550

Query: 61   LKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERIN-TELVGSPGKHQHQEEGN 119
            +K+         ++  L  + G  ++  +  + L   +ER+  T       + +  EE  
Sbjct: 1551 VKD---------QEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601

Query: 120  VTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRY 179
             + +   +   + L   +       D Q   R+           S Q  R      K+  
Sbjct: 1602 QSCQKKLKQMEVQLEEEYE------DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLR 1655

Query: 180  QDLQE-KLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENE 238
            +DL+  K LL++A +             L   +  K++  Q++  L++  + TC  +   
Sbjct: 1656 KDLKRTKALLADAQLMLDH---------LKNSAPSKREIAQLKNQLEESEF-TCAAAVKA 1705

Query: 239  AEREETTSPECEE-HNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGK-QEEFRV 296
             +  E    E E+ H  + ++   +    EQ  R        E+  ++N+L + QE+   
Sbjct: 1706 RKAMEV---EIEDLHLQIDDIAKAKTALEEQLSR-----LQREKNEIQNRLEEDQEDMNE 1757

Query: 297  YGKSENILVLRKD-----IKDLKAQLQNANKVIQNLKSRVRSL 334
              K     V +       I DL+AQL+ ANK  Q L+ ++++L
Sbjct: 1758 LMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800



 Score = 28.9 bits (63), Expect = 9.2
 Identities = 33/143 (23%), Positives = 59/143 (41%), Gaps = 6/143 (4%)

Query: 10   ELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIIN 69
            + KE+MGE      E    K + E+ +E++       ++ L+  F+++ G L+ A     
Sbjct: 1882 DTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRI-GDLQAAIEDEM 1940

Query: 70   LLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPRPQ 129
               E   L + EG+S +  E    L   ++ + + L  + G  +   +        P   
Sbjct: 1941 ESDENEDLINSEGDSDVDSE----LEDRVDGVKSWLSKNKGPSKAASDDGSLKSSSPTSY 1996

Query: 130  SLDLGATFTVDAHQ-LDNQSQPR 151
               L    + D H  LDN S+PR
Sbjct: 1997 WKSLAPDRSDDEHDPLDNTSRPR 2019


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 87/416 (20%), Positives = 163/416 (39%), Gaps = 48/416 (11%)

Query: 24   EIEEDKEKGE--VMVETVVTKEGLSESSLQAEFR-KLQGKLKNAHNIINLL--------- 71
            E+++D   GE  +  E  V +   ++  LQ EF  KL+ + +N   +   L         
Sbjct: 1361 EVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEE 1420

Query: 72   KEQLVLSSKEGNSKLTPELL---VHLTSTIERINTELVGSPGK--------HQHQEEGNV 120
             ++ +   K+   +LT EL    +HL     R N EL     +        H+  +   +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVR-NHELEKKQRRFDSELSQAHEEAQREKL 1479

Query: 121  TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ 180
                  R + + L   F++   QL+ +        Q   SL    Q + SQ S+ +    
Sbjct: 1480 QREKLQREKDMLLAEAFSLK-QQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538

Query: 181  DLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAE 240
             ++++L   EA V  Q  EL++    +    +++Q   +++++++ +        E+  E
Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTI---QMLEQAKLRLEMEMERMRQTHSKEMESRDE 1595

Query: 241  REETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKS 300
              E     C++     E+ L E    +Q           E++ LE +L    +       
Sbjct: 1596 EVEEARQSCQKKLKQMEVQLEEEYEDKQ-------KVLREKRELEGKLATLSDQVNRRDF 1648

Query: 301  ENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSS 360
            E+   LRKD+K  KA L +A  ++ +LK+   S    +   + LE   +      ++   
Sbjct: 1649 ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEE-SEFTCAAAVKARK 1707

Query: 361  PHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEE 416
               V  ED     D          +AK  LE  + R+     Q  KN ++ +L E+
Sbjct: 1708 AMEVEIEDLHLQIDDIA-------KAKTALEEQLSRL-----QREKNEIQNRLEED 1751



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 70/343 (20%), Positives = 136/343 (39%), Gaps = 45/343 (13%)

Query: 4    LCLENAELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSL---QAEFRKLQGK 60
            L  E   LK+Q+ E   D     +     E  ++ + ++E   E+SL   + + R L+ K
Sbjct: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550

Query: 61   LKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERIN-TELVGSPGKHQHQEEGN 119
            +K+         ++  L  + G  ++  +  + L   +ER+  T       + +  EE  
Sbjct: 1551 VKD---------QEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601

Query: 120  VTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRY 179
             + +   +   + L   +       D Q   R+           S Q  R      K+  
Sbjct: 1602 QSCQKKLKQMEVQLEEEYE------DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLR 1655

Query: 180  QDLQE-KLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENE 238
            +DL+  K LL++A +             L   +  K++  Q++  L++  + TC  +   
Sbjct: 1656 KDLKRTKALLADAQLMLDH---------LKNSAPSKREIAQLKNQLEESEF-TCAAAVKA 1705

Query: 239  AEREETTSPECEE-HNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGK-QEEFRV 296
             +  E    E E+ H  + ++   +    EQ  R        E+  ++N+L + QE+   
Sbjct: 1706 RKAMEV---EIEDLHLQIDDIAKAKTALEEQLSR-----LQREKNEIQNRLEEDQEDMNE 1757

Query: 297  YGKSENILVLRKD-----IKDLKAQLQNANKVIQNLKSRVRSL 334
              K     V +       I DL+AQL+ ANK  Q L+ ++++L
Sbjct: 1758 LMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800


>gi|154277118 spectrin repeat containing, nuclear envelope 1 isoform
           4 [Homo sapiens]
          Length = 3321

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 75/337 (22%), Positives = 141/337 (41%), Gaps = 65/337 (19%)

Query: 11  LKEQMGETMSDGWEIEEDKEKGEVMVETVVTK-------------EGLSESSLQAEFRKL 57
           LK  + E     +E  E ++K +  ++++ TK              G S  S  AE + L
Sbjct: 471 LKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQAL 530

Query: 58  QGKLKNAHNIINLLK----EQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQ 113
             ++    + IN L+    E+LV  S E +      L   LT   ER++T  + + GK Q
Sbjct: 531 MDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQ 590

Query: 114 HQEEG-NVTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQL 172
             EE  N  +    + Q+L     +  +A +LD+          +A S P     + +QL
Sbjct: 591 LLEEKLNDQLEEQRQEQALQ---RYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQL 647

Query: 173 SQCKQRYQDLQEKLL-LSEATVFAQANELEKYRVMLTGESLVKQDSKQI----------- 220
             C+    ++++K++ LSE +V  +        ++L G++  K +++Q+           
Sbjct: 648 MDCQNMLVEIEQKVVALSELSVHNE-------NLLLEGKAHTKDEAEQLAGKLRRLKGSL 700

Query: 221 ----------QVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGR 270
                     Q+++Q    E   + E++ +   T SP  +E        L +   +   +
Sbjct: 701 LELQRALHDKQLNMQGTAQE---KEESDVDLTATQSPGVQEW-------LAQARTTWTQQ 750

Query: 271 RGSTLASSSERKPLENQLGKQEEF--RVYGKSENILV 305
           R S+L    ++K LE +L +Q+     V  + E IL+
Sbjct: 751 RQSSL---QQQKELEQELAEQKSLLRSVASRGEEILI 784


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 75/337 (22%), Positives = 141/337 (41%), Gaps = 65/337 (19%)

Query: 11   LKEQMGETMSDGWEIEEDKEKGEVMVETVVTK-------------EGLSESSLQAEFRKL 57
            LK  + E     +E  E ++K +  ++++ TK              G S  S  AE + L
Sbjct: 5876 LKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQAL 5935

Query: 58   QGKLKNAHNIINLLK----EQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQ 113
              ++    + IN L+    E+LV  S E +      L   LT   ER++T  + + GK Q
Sbjct: 5936 MDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQ 5995

Query: 114  HQEEG-NVTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQL 172
              EE  N  +    + Q+L     +  +A +LD+          +A S P     + +QL
Sbjct: 5996 LLEEKLNDQLEEQRQEQALQ---RYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQL 6052

Query: 173  SQCKQRYQDLQEKLL-LSEATVFAQANELEKYRVMLTGESLVKQDSKQI----------- 220
              C+    ++++K++ LSE +V  +        ++L G++  K +++Q+           
Sbjct: 6053 MDCQNMLVEIEQKVVALSELSVHNE-------NLLLEGKAHTKDEAEQLAGKLRRLKGSL 6105

Query: 221  ----------QVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGR 270
                      Q+++Q    E   + E++ +   T SP  +E        L +   +   +
Sbjct: 6106 LELQRALHDKQLNMQGTAQE---KEESDVDLTATQSPGVQEW-------LAQARTTWTQQ 6155

Query: 271  RGSTLASSSERKPLENQLGKQEEF--RVYGKSENILV 305
            R S+L    ++K LE +L +Q+     V  + E IL+
Sbjct: 6156 RQSSL---QQQKELEQELAEQKSLLRSVASRGEEILI 6189


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 75/337 (22%), Positives = 141/337 (41%), Gaps = 65/337 (19%)

Query: 11   LKEQMGETMSDGWEIEEDKEKGEVMVETVVTK-------------EGLSESSLQAEFRKL 57
            LK  + E     +E  E ++K +  ++++ TK              G S  S  AE + L
Sbjct: 5947 LKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQAL 6006

Query: 58   QGKLKNAHNIINLLK----EQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQ 113
              ++    + IN L+    E+LV  S E +      L   LT   ER++T  + + GK Q
Sbjct: 6007 MDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQ 6066

Query: 114  HQEEG-NVTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQL 172
              EE  N  +    + Q+L     +  +A +LD+          +A S P     + +QL
Sbjct: 6067 LLEEKLNDQLEEQRQEQALQ---RYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQL 6123

Query: 173  SQCKQRYQDLQEKLL-LSEATVFAQANELEKYRVMLTGESLVKQDSKQI----------- 220
              C+    ++++K++ LSE +V  +        ++L G++  K +++Q+           
Sbjct: 6124 MDCQNMLVEIEQKVVALSELSVHNE-------NLLLEGKAHTKDEAEQLAGKLRRLKGSL 6176

Query: 221  ----------QVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGR 270
                      Q+++Q    E   + E++ +   T SP  +E        L +   +   +
Sbjct: 6177 LELQRALHDKQLNMQGTAQE---KEESDVDLTATQSPGVQEW-------LAQARTTWTQQ 6226

Query: 271  RGSTLASSSERKPLENQLGKQEEF--RVYGKSENILV 305
            R S+L    ++K LE +L +Q+     V  + E IL+
Sbjct: 6227 RQSSL---QQQKELEQELAEQKSLLRSVASRGEEILI 6260


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 49/192 (25%), Positives = 85/192 (44%), Gaps = 17/192 (8%)

Query: 168 LRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVK--QDSKQIQVDLQ 225
           L++++   K+    L+E       T   QA E E  ++    + ++K  Q+S++I+ +  
Sbjct: 399 LKAEMDSHKETKDKLKET-----TTKLTQAKE-EADQIRKNCQDMIKTYQESEEIKSNEL 452

Query: 226 DLGYETCGRSENEAEREETTSPECEEHNSLKEM-----VLMEGLCSEQGRRGSTLASSSE 280
           D       + E E + +E +      H  +KE+        EG+   +  R        E
Sbjct: 453 DAKLRVT-KGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDE 511

Query: 281 RKPLENQLGKQEEF--RVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSL-SVT 337
           R   E++L K +E   R   + +N+L   K    L+ QLQ   + I+NLK  V SL S+ 
Sbjct: 512 RLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLI 571

Query: 338 SDYSSSLERPRK 349
           +D    +E  RK
Sbjct: 572 NDLQKDIEGSRK 583



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 76/350 (21%), Positives = 147/350 (42%), Gaps = 52/350 (14%)

Query: 5   CLENAELKEQMGETMSDGWEIEEDKEKGEV--MVETVVTKEGLSESSLQA--EFRKLQGK 60
           CLE+  L+ +  + +S   EI  +++K E+  +++ V T + L E   +   E   L+ +
Sbjct: 507 CLEDERLRTE--DELSKYKEII-NRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEE 563

Query: 61  LKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNV 120
           +++ +++IN L++ +     EG+ K   ELL+  T  +   N +L         Q E N 
Sbjct: 564 VESLNSLINDLQKDI-----EGSRKRESELLL-FTERLTSKNAQL---------QSESNS 608

Query: 121 TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ 180
               F +          +    QL +Q +       +  S     + LR      K+  Q
Sbjct: 609 LQSQFDK---------VSCSESQLQSQCEQMKQTNINLESRLLKEEELR------KEEVQ 653

Query: 181 DLQEKLLLSEATVFAQANELEKYRVMLTGE-----SLVKQDSKQIQVDLQDLGYETCGRS 235
            LQ +L   +  V A + ++E+ +  L  +     S +K  +KQ+Q   + L     G  
Sbjct: 654 TLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQVESGSY 713

Query: 236 ENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSS----ERKPLENQLGKQ 291
           + E     + S       SL      E    E    GS++A  +    ++  L  ++ + 
Sbjct: 714 DKEVSSMGSRS---SSSGSLNARSSAEDRSPEN--TGSSVAVDNFPQVDKAMLIERIVRL 768

Query: 292 EEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYS 341
           ++     K+E I  +   IK L  +++   K+IQ+   R  S +++S+ S
Sbjct: 769 QKAHAR-KNEKIEFMEDHIKQLVEEIRKKTKIIQSYILREESGTLSSEAS 817



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 57/266 (21%), Positives = 113/266 (42%), Gaps = 31/266 (11%)

Query: 164 STQHLRSQLSQCKQRYQDLQEKL-----LLSEATVFAQANELEKYRVMLTGESLVKQDSK 218
           +   L+ QL + KQ  ++L+E++     L+++     + +   +  ++L  E L  +++ 
Sbjct: 542 TADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNA- 600

Query: 219 QIQVDLQDLGYE----TCGRSENEAEREETTSPECE-EHNSLKEMVLMEGLCSEQGRRGS 273
           Q+Q +   L  +    +C  S+ +++ E+        E   LKE  L +     Q  +  
Sbjct: 601 QLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKE--EVQTLQAE 658

Query: 274 TLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRS 333
                +E K L  Q+ + ++  V  + ++       IKDL  QLQ A + +  ++S    
Sbjct: 659 LACRQTEVKALSTQVEELKDELVTQRRKHA----SSIKDLTKQLQQARRKLDQVESGSYD 714

Query: 334 LSVTSDYSSSLERPRKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESL 393
             V+S  S S      L A  + E  SP            + TG+  +     + D   L
Sbjct: 715 KEVSSMGSRS-SSSGSLNARSSAEDRSP------------ENTGSSVAVDNFPQVDKAML 761

Query: 394 IQRVSQLE-AQLPKNGLEEKLAEELR 418
           I+R+ +L+ A   KN   E + + ++
Sbjct: 762 IERIVRLQKAHARKNEKIEFMEDHIK 787



 Score = 32.3 bits (72), Expect = 0.84
 Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 31/151 (20%)

Query: 210 ESLVKQDSKQIQVDLQDLGYETCGRSEN-EAEREETTSPECEEHNSLKEMVL-MEGLCSE 267
           + L+K++ K      Q+L  + C   +N   E ++ T  E +  N++K++   +E L  E
Sbjct: 210 KKLIKENKKH-----QELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKE 264

Query: 268 -QGRRGSTLASSSERKPLENQLGKQ------------EEFR----------VYGKSENIL 304
            +  R   +A     K    QL K+            EE R          V G+ E+ L
Sbjct: 265 VKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKES-L 323

Query: 305 VLRKDIKDLKAQLQNANKVIQNLKSRVRSLS 335
            LRK+ + L+ +L++ANK ++   ++++ LS
Sbjct: 324 DLRKEKETLEKKLRDANKELEKNTNKIKQLS 354


>gi|92110019 hypothetical protein LOC55672 [Homo sapiens]
          Length = 1214

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 78/366 (21%), Positives = 151/366 (41%), Gaps = 51/366 (13%)

Query: 7   ENAELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHN 66
           E   L + + + +S   E +ED+++ +V VE     E + ESS   E +K +       +
Sbjct: 150 EGCRLAQHLVQKLSP--ENDEDEDE-DVQVEEA---EKVLESSAPREVQKAEESKVPEDS 203

Query: 67  IINLLKEQLVLSSKEGNSKLT---PELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVR 123
           +     E+  ++    +       P   +++T   +++N+ LV        + +  V + 
Sbjct: 204 L-----EECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTLVVDRESSHDECQDAVNIL 258

Query: 124 PFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQ 183
           P P P S     +  V A  L ++        ++  ++    + LR QL++ KQ++++L+
Sbjct: 259 PVPGPTSSATNVSMVVSAGPLSSE--------KAEMNILEMNEKLRPQLAEKKQQFRNLK 310

Query: 184 EKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREE 243
           EK  +++   F  AN+  KY+     + +      + Q   + L       +E   + EE
Sbjct: 311 EKCFVTQLAGFL-ANQQNKYKYEECEDLIKSMLRNERQFKEEKL-------AEQLKQAEE 362

Query: 244 TTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSENI 303
               +   H+  +E+  +     E+ R G   AS S  + L+  L   E  +  G     
Sbjct: 363 LRQYKVLVHSQERELTQLR----EKLREGRD-ASRSLNQHLQALLTPDEPDKSQG----- 412

Query: 304 LVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSSPHS 363
                  +DL+ QL    ++ Q+L   V+ LS  +D     E  +   A   LE S+P  
Sbjct: 413 -------QDLQEQLAEGCRLAQHL---VQKLSPENDEDED-EDVQVEEAEKVLESSAPRE 461

Query: 364 VPDEDE 369
           V   +E
Sbjct: 462 VQKAEE 467



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 43/201 (21%), Positives = 91/201 (45%), Gaps = 23/201 (11%)

Query: 7   ENAELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHN 66
           E   L + + + +S   E +ED+++ +V VE     E + ESS   E +K +       +
Sbjct: 421 EGCRLAQHLVQKLSP--ENDEDEDE-DVQVEEA---EKVLESSAPREVQKAEESKVPEDS 474

Query: 67  IINLLKEQLVLSSKEGNSKLT---PELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVR 123
           +     E+  ++    +       P   +++T   +++N+ LV        + +  V + 
Sbjct: 475 L-----EECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNIL 529

Query: 124 PFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQ 183
           P P P S     +  V A  L ++        ++  ++    + LR QL++ KQ++++L+
Sbjct: 530 PVPGPTSSATNVSMVVSAGPLSSE--------KAEMNILEMNEKLRPQLAEKKQQFRNLK 581

Query: 184 EKLLLSEATVFAQANELEKYR 204
           EK  +++   F  AN+  KY+
Sbjct: 582 EKCFVTQLACFL-ANQQNKYK 601



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 49/204 (24%), Positives = 87/204 (42%), Gaps = 29/204 (14%)

Query: 166 QHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQ 225
           + LR QL++ KQ++++L+EK  +++   F  AN  +KY+     + +      + Q   +
Sbjct: 22  EKLRPQLAENKQQFRNLKEKCFVTQLAGFL-ANRQKKYKYEECKDLIKFMLRNERQFKEE 80

Query: 226 DLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLE 285
            L       +E   + EE    +   H+  +E+  +     E+ R G   AS S  + L+
Sbjct: 81  KL-------AEQLKQAEELRQYKVLVHSQERELTQLR----EKLREGRD-ASRSLNQHLQ 128

Query: 286 NQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLE 345
             L   E  +  G            +DL+ QL    ++ Q+L   V+ LS  +D     E
Sbjct: 129 ALLTPDEPDKSQG------------QDLQEQLAEGCRLAQHL---VQKLSPENDEDED-E 172

Query: 346 RPRKLRAVGTLEGSSPHSVPDEDE 369
             +   A   LE S+P  V   +E
Sbjct: 173 DVQVEEAEKVLESSAPREVQKAEE 196


>gi|28269672 serologically defined colon cancer antigen 8 [Homo
           sapiens]
          Length = 713

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 64/295 (21%), Positives = 124/295 (42%), Gaps = 32/295 (10%)

Query: 33  EVMVETVVTKEGLSE-----------SSLQAEFRKLQGKLKNAHNIINLLKEQLVLSSKE 81
           E  VE V TKE +S            +S + +  K+ G+++   N  N+ K++     +E
Sbjct: 419 EAQVEKV-TKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHRE 477

Query: 82  GNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPRPQSLDLGATFTVDA 141
             +K   +L +     IE++  EL  S  +H  QE+    +    R + L L        
Sbjct: 478 FRAKTNRDLEIK-DQEIEKLRIELDESK-QHLEQEQQKAALA---REECLRLTELLGESE 532

Query: 142 HQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELE 201
           HQL    Q +D   QS       ++  ++Q  Q +QR Q+L +K+   EA       E E
Sbjct: 533 HQLHLTRQEKDSIQQSF------SKEAKAQALQAQQREQELTQKIQQMEAQ--HDKTENE 584

Query: 202 KYRVMLTGESL----VKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKE 257
           +Y ++LT ++     +K++   +   L+ +  +T       ++ +  T  +  +     E
Sbjct: 585 QY-LLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNE 643

Query: 258 MVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKD 312
              +E  C + GR   T+     +    +Q   Q+  ++  K   +L+ R+ + +
Sbjct: 644 E--LEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSE 696



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 62/276 (22%), Positives = 110/276 (39%), Gaps = 40/276 (14%)

Query: 168 LRSQLSQCKQR----YQDLQEKLLLSEATVFAQAN----------ELEKYRVMLTGESLV 213
           +RS L+  +QR    Y+ +++ L +SE   F +            ELE+    L  E   
Sbjct: 322 VRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELAS 381

Query: 214 KQDSKQIQVDLQD---------LGYETCGRSEN----EAEREETTSPECEEHNSLKEMVL 260
           +Q+ + I+ D+           +G +    S+N    EA+ E+ T  +    N L+E  +
Sbjct: 382 QQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEE--I 439

Query: 261 MEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNA 320
              L S +      +  +     +  QL K    +   + E+     K  +DL+ + Q  
Sbjct: 440 QSQLASRE------MDVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEI 493

Query: 321 NKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSSPHSVP---DEDEGWLSDGTG 377
            K+   L    + L       ++L R   LR    L G S H +     E +      + 
Sbjct: 494 EKLRIELDESKQHLE-QEQQKAALAREECLRLTELL-GESEHQLHLTRQEKDSIQQSFSK 551

Query: 378 AFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKL 413
              +  LQA++  + L Q++ Q+EAQ  K   E+ L
Sbjct: 552 EAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYL 587


>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
          Length = 508

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 59/241 (24%), Positives = 99/241 (41%), Gaps = 37/241 (15%)

Query: 164 STQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELE----KYRVMLTGESLVKQDSKQ 219
           S QHL  +  + +Q   +L+  L    A   A+A ELE      R  L  +   +QDS +
Sbjct: 86  SAQHLERE-ERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSEQQDSGR 144

Query: 220 IQVD-LQDLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASS 278
            +   L +L  +    S+  A+  +T      E    +E+  + G C  Q   G+ L + 
Sbjct: 145 ERARALSELSEQNLRLSQQLAQASQT------EQELQRELDALRGQCQAQALAGAELRTR 198

Query: 279 SERKPLENQL-------------GKQEEF-----RVYGKSENILVLRKDIKDLKAQLQNA 320
            E    ENQ+             G +EE      R+    E +L+LR++ ++   +L+ A
Sbjct: 199 LESLQGENQMLQSRRQDLEAQIRGLREEVEKGEGRLQTTHEELLLLRRERREHSLELERA 258

Query: 321 NKVIQNLKSRVRSLSVTSDYSSSLERPRKLR----AVGTLEGSSPHSVPDEDEGWLSDGT 376
                   S +R L       S LE   +L+    +  +L+    HS+ D D+G  +D  
Sbjct: 259 RSEAGEALSALRRL---QRRVSELEEESRLQDADVSAASLQSELAHSLDDGDQGQGADAP 315

Query: 377 G 377
           G
Sbjct: 316 G 316


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 70/334 (20%), Positives = 139/334 (41%), Gaps = 55/334 (16%)

Query: 29   KEKGEVM--VETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINLLKEQLVLSSKEGNSKL 86
            ++K E +  ++  +TK+   +  L+ +F  L  + K  H  +N   +  V   ++   K+
Sbjct: 789  QKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQK--VKM 846

Query: 87   TPELLVHLTSTIE----RINTELVGSPGKHQHQ-EEGNVTVRPFPRPQSLDLGATFTVDA 141
              E L+   ST++    +++  L  S  + + + ++G   +        LDL  T     
Sbjct: 847  EKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAI--------LDLEKTCKELK 898

Query: 142  HQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELE 201
            HQL  Q +      +    L  S +  +    Q K     +QE+L+ ++ T+  + NE E
Sbjct: 899  HQLQVQMENT---LKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTL--KQNEKE 953

Query: 202  KYRVMLTGESLVK---QDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEM 258
            + ++      L +   Q  KQI+    +L      ++E E + ++  +   +E  + KE 
Sbjct: 954  EQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEK 1013

Query: 259  VLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDL----- 313
            +             S L ++ E+     +  KQ +   YG+   +L  R+D+K +     
Sbjct: 1014 I-------------SVLQNNYEKS---QETFKQLQSDFYGRESELLATRQDLKSVEEKLS 1057

Query: 314  ---------KAQLQNANKVIQNLKSRVRSLSVTS 338
                     + Q+ N NK+IQ LK+   +L   S
Sbjct: 1058 LAQEDLISNRNQIGNQNKLIQELKTAKATLEQDS 1091



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 55/258 (21%), Positives = 110/258 (42%), Gaps = 30/258 (11%)

Query: 168  LRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDL 227
            L ++LS  K +   + + L  S++  F + N+  K  + L  E   K+   Q+QV +++ 
Sbjct: 851  LMTELSTVKDKLSKVSDSLKNSKSE-FEKENQKGKAAI-LDLEKTCKELKHQLQVQMENT 908

Query: 228  GYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQ 287
              E     ++  + +E +     E NS++E ++      +Q  +       +  +  ++ 
Sbjct: 909  LKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSS 968

Query: 288  LGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSV-TSDYSSSLER 346
              K+++         I VL+K   + K Q Q   +  Q L +    +SV  ++Y  S E 
Sbjct: 969  EQKKKQIEALQGELKIAVLQKTELENKLQ-QQLTQAAQELAAEKEKISVLQNNYEKSQET 1027

Query: 347  PRKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPK 406
             ++L+                     SD  G   S  L  ++DL+S+ +++S  +  L  
Sbjct: 1028 FKQLQ---------------------SDFYGR-ESELLATRQDLKSVEEKLSLAQEDLIS 1065

Query: 407  N----GLEEKLAEELRSA 420
            N    G + KL +EL++A
Sbjct: 1066 NRNQIGNQNKLIQELKTA 1083



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 41/189 (21%), Positives = 74/189 (39%), Gaps = 41/189 (21%)

Query: 164 STQHLRSQLSQCKQRYQ----------------------------DLQEKLLLSEATVFA 195
           +TQ L+ +LS+ + +YQ                             L  KLL +E  +  
Sbjct: 373 ATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGE 432

Query: 196 QANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNSL 255
               L++ R  L+ E L+  D +Q   DLQ        R E + + + T S E +     
Sbjct: 433 AHGRLKEQR-QLSSEKLM--DKEQQVADLQ----LKLSRLEEQLKEKVTNSTELQHQLDK 485

Query: 256 KEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQE------EFRVYGKSENILVLRKD 309
            +    E    +Q        + ++ + +  Q+G ++      E  +    ENI +L K+
Sbjct: 486 TKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKE 545

Query: 310 IKDLKAQLQ 318
            +DL A++Q
Sbjct: 546 REDLYAKIQ 554


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 72/325 (22%), Positives = 138/325 (42%), Gaps = 62/325 (19%)

Query: 143 QLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEK 202
           ++D   Q          +L    + L +Q S CKQ  + L+E L   E        E++ 
Sbjct: 435 KIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDA 494

Query: 203 YRVMLTG-ESLVKQDSKQIQV-------------DLQDLGYETCGRSENEAER-----EE 243
            R+ L   ES + + +KQ+Q              D++D+  E   R  N  ++     +E
Sbjct: 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDM-LEVKERKINVLQKKIENLQE 553

Query: 244 TTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASS----SERKPLENQLGKQEEFRVYGK 299
               + ++  +LK+ V  + L ++     + LA+     SE++ +  +L +Q E     +
Sbjct: 554 QLRDKDKQLTNLKDRV--KSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRER 611

Query: 300 SENILVLRKDIKDLK-------AQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRA 352
            E I   RK+ KDLK       A+L      + +LK    SL+     S+ L+R  KL++
Sbjct: 612 LEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLA-----SAGLKRDSKLKS 666

Query: 353 V-----------GTLEG--SSPHSVPDE--------DEGWLSDGTGAFYSPGL-QAKKDL 390
           +             LE      H++ D+        D+    D   ++Y     +A+ ++
Sbjct: 667 LEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEV 726

Query: 391 ESLIQRVSQLEAQLPKNGLEEKLAE 415
           + L++ + ++E +  KN  ++K+AE
Sbjct: 727 DRLLEILKEVENE--KNDKDKKIAE 749


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 57/271 (21%), Positives = 110/271 (40%), Gaps = 26/271 (9%)

Query: 157  SAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEK----YRVMLTGESL 212
            +A +L    ++    L++ KQ+Y++ Q +L  S+    + + EL K    Y   L     
Sbjct: 1438 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497

Query: 213  VKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRG 272
             K+++K +Q ++ DL  E  G S       E    + E      +  L E   S +   G
Sbjct: 1498 FKRENKNLQEEISDL-TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEG 1556

Query: 273  STLASSSE----RKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLK 328
              L +  E    +  +E +L +++E     K  ++ V+      L A+ ++ N+ ++  K
Sbjct: 1557 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKK 1616

Query: 329  SRVRSLSVTSDYSSSLERPRKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKK 388
                 L   ++    L    ++ A    +  S  S+  + +  L D         ++A  
Sbjct: 1617 KMEGDL---NEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDD--------AVRAND 1665

Query: 389  DLESLIQRVSQLEAQLPKNGLEEKLAEELRS 419
            DL+  I  V +      +N L +   EELR+
Sbjct: 1666 DLKENIAIVER------RNNLLQAELEELRA 1690



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 72/294 (24%), Positives = 110/294 (37%), Gaps = 49/294 (16%)

Query: 171  QLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYE 230
            +++  K+ +  L+E L  SEA    +  ELE+  V L  E    Q   Q + D      E
Sbjct: 848  EMASMKEEFTRLKEALEKSEA----RRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903

Query: 231  TC-----GRSENEAEREETTSPECEEHNSLKEMVL----MEGLCSEQGRRGS----TLAS 277
             C      + + EA+ +E      +E     E+      +E  CSE  R       TLA 
Sbjct: 904  RCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK 963

Query: 278  SSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNA--------NKVIQNLKS 329
              + K       K     + G  E I  L K+ K L+   Q A        +KV    K+
Sbjct: 964  VEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023

Query: 330  RVRSLSVTSDYSSSLERPRKLR-----AVGTLEGS---SPHSVPDEDE------------ 369
            +V+      D   SLE+ +K+R     A   LEG    +  S+ D +             
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083

Query: 370  ----GWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRS 419
                  L+       + G Q +K L+ L  R+ +LE +L          E+LRS
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRS 1137


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 47/243 (19%), Positives = 100/243 (41%), Gaps = 38/243 (15%)

Query: 9   AELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNII 68
           AE++E+  +  +  +++++ +E+   + + +V    LS S  Q E  KLQ  ++  +  +
Sbjct: 210 AEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQ-EHVKLQKLMEKKNQEL 268

Query: 69  NLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQE---EGNVTVRPF 125
            ++++Q     +E         L    STI+ +  ++  + G  +  E   + N+ +   
Sbjct: 269 EVVRQQRERLQEE---------LSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEK 319

Query: 126 PRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEK 185
            R     +G    ++    + Q   R+           +   LR QL     R ++ Q++
Sbjct: 320 VRELRETVGDLEAMNEMNDELQENARE-----------TELELREQLDMAGARVREAQKR 368

Query: 186 LLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETT 245
           +  ++ TV      ++KYR              Q+   LQD+  E   + E   ER++  
Sbjct: 369 VEAAQETVADYQQTIKKYR--------------QLTAHLQDVNRELTNQQEASVERQQQP 414

Query: 246 SPE 248
            PE
Sbjct: 415 PPE 417



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 73/305 (23%), Positives = 120/305 (39%), Gaps = 80/305 (26%)

Query: 130 SLDLGATFTVDAHQLDNQSQPRDPG---------PQSAFSLPGSTQHLRSQLSQ---CKQ 177
           S  LG + +  A +L + S+P  P          P    + PG+   L S   +    + 
Sbjct: 30  SSSLGPSGSASAGELSS-SEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRA 88

Query: 178 RYQDLQEKL---LLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGR 234
           + +DL+EKL    L  A   A+  ELEK+++ L      K   ++ Q DLQ    E    
Sbjct: 89  QVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKE 148

Query: 235 SENEAEREETTSPEC-------------------------EEHNSLKEMV--------LM 261
           ++   E +E    E                          +E  +LKE V        ++
Sbjct: 149 AKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEIL 208

Query: 262 EGLCSEQGRRGSTLASSSERKPLENQLG----------------KQEEFRVY----GKSE 301
           +    E+G  G+  ASS + K LE Q                  KQE  ++      K++
Sbjct: 209 KAEIEEKGSDGA--ASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQ 266

Query: 302 NILVLRKDIKDLKAQLQNANKVIQNLKSRV-------RSLSVTSDYSSSL-ERPRKLR-A 352
            + V+R+  + L+ +L  A   I  LK +V         + + +D + +L E+ R+LR  
Sbjct: 267 ELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRET 326

Query: 353 VGTLE 357
           VG LE
Sbjct: 327 VGDLE 331


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 47/243 (19%), Positives = 100/243 (41%), Gaps = 38/243 (15%)

Query: 9   AELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNII 68
           AE++E+  +  +  +++++ +E+   + + +V    LS S  Q E  KLQ  ++  +  +
Sbjct: 324 AEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQ-EHVKLQKLMEKKNQEL 382

Query: 69  NLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQE---EGNVTVRPF 125
            ++++Q     +E         L    STI+ +  ++  + G  +  E   + N+ +   
Sbjct: 383 EVVRQQRERLQEE---------LSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEK 433

Query: 126 PRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEK 185
            R     +G    ++    + Q   R+           +   LR QL     R ++ Q++
Sbjct: 434 VRELRETVGDLEAMNEMNDELQENARE-----------TELELREQLDMAGARVREAQKR 482

Query: 186 LLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETT 245
           +  ++ TV      ++KYR              Q+   LQD+  E   + E   ER++  
Sbjct: 483 VEAAQETVADYQQTIKKYR--------------QLTAHLQDVNRELTNQQEASVERQQQP 528

Query: 246 SPE 248
            PE
Sbjct: 529 PPE 531



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 73/305 (23%), Positives = 120/305 (39%), Gaps = 80/305 (26%)

Query: 130 SLDLGATFTVDAHQLDNQSQPRDPG---------PQSAFSLPGSTQHLRSQLSQ---CKQ 177
           S  LG + +  A +L + S+P  P          P    + PG+   L S   +    + 
Sbjct: 144 SSSLGPSGSASAGELSS-SEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRA 202

Query: 178 RYQDLQEKL---LLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGR 234
           + +DL+EKL    L  A   A+  ELEK+++ L      K   ++ Q DLQ    E    
Sbjct: 203 QVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKE 262

Query: 235 SENEAEREETTSPEC-------------------------EEHNSLKEMV--------LM 261
           ++   E +E    E                          +E  +LKE V        ++
Sbjct: 263 AKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEIL 322

Query: 262 EGLCSEQGRRGSTLASSSERKPLENQLG----------------KQEEFRVY----GKSE 301
           +    E+G  G+  ASS + K LE Q                  KQE  ++      K++
Sbjct: 323 KAEIEEKGSDGA--ASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQ 380

Query: 302 NILVLRKDIKDLKAQLQNANKVIQNLKSRV-------RSLSVTSDYSSSL-ERPRKLR-A 352
            + V+R+  + L+ +L  A   I  LK +V         + + +D + +L E+ R+LR  
Sbjct: 381 ELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRET 440

Query: 353 VGTLE 357
           VG LE
Sbjct: 441 VGDLE 445


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 47/243 (19%), Positives = 100/243 (41%), Gaps = 38/243 (15%)

Query: 9   AELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNII 68
           AE++E+  +  +  +++++ +E+   + + +V    LS S  Q E  KLQ  ++  +  +
Sbjct: 210 AEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQ-EHVKLQKLMEKKNQEL 268

Query: 69  NLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQE---EGNVTVRPF 125
            ++++Q     +E         L    STI+ +  ++  + G  +  E   + N+ +   
Sbjct: 269 EVVRQQRERLQEE---------LSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEK 319

Query: 126 PRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEK 185
            R     +G    ++    + Q   R+           +   LR QL     R ++ Q++
Sbjct: 320 VRELRETVGDLEAMNEMNDELQENARE-----------TELELREQLDMAGARVREAQKR 368

Query: 186 LLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETT 245
           +  ++ TV      ++KYR              Q+   LQD+  E   + E   ER++  
Sbjct: 369 VEAAQETVADYQQTIKKYR--------------QLTAHLQDVNRELTNQQEASVERQQQP 414

Query: 246 SPE 248
            PE
Sbjct: 415 PPE 417



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 73/305 (23%), Positives = 120/305 (39%), Gaps = 80/305 (26%)

Query: 130 SLDLGATFTVDAHQLDNQSQPRDPG---------PQSAFSLPGSTQHLRSQLSQ---CKQ 177
           S  LG + +  A +L + S+P  P          P    + PG+   L S   +    + 
Sbjct: 30  SSSLGPSGSASAGELSS-SEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRA 88

Query: 178 RYQDLQEKL---LLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGR 234
           + +DL+EKL    L  A   A+  ELEK+++ L      K   ++ Q DLQ    E    
Sbjct: 89  QVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKE 148

Query: 235 SENEAEREETTSPEC-------------------------EEHNSLKEMV--------LM 261
           ++   E +E    E                          +E  +LKE V        ++
Sbjct: 149 AKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEIL 208

Query: 262 EGLCSEQGRRGSTLASSSERKPLENQLG----------------KQEEFRVY----GKSE 301
           +    E+G  G+  ASS + K LE Q                  KQE  ++      K++
Sbjct: 209 KAEIEEKGSDGA--ASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQ 266

Query: 302 NILVLRKDIKDLKAQLQNANKVIQNLKSRV-------RSLSVTSDYSSSL-ERPRKLR-A 352
            + V+R+  + L+ +L  A   I  LK +V         + + +D + +L E+ R+LR  
Sbjct: 267 ELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRET 326

Query: 353 VGTLE 357
           VG LE
Sbjct: 327 VGDLE 331


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 47/243 (19%), Positives = 100/243 (41%), Gaps = 38/243 (15%)

Query: 9   AELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNII 68
           AE++E+  +  +  +++++ +E+   + + +V    LS S  Q E  KLQ  ++  +  +
Sbjct: 344 AEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQ-EHVKLQKLMEKKNQEL 402

Query: 69  NLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQE---EGNVTVRPF 125
            ++++Q     +E         L    STI+ +  ++  + G  +  E   + N+ +   
Sbjct: 403 EVVRQQRERLQEE---------LSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEK 453

Query: 126 PRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEK 185
            R     +G    ++    + Q   R+           +   LR QL     R ++ Q++
Sbjct: 454 VRELRETVGDLEAMNEMNDELQENARE-----------TELELREQLDMAGARVREAQKR 502

Query: 186 LLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETT 245
           +  ++ TV      ++KYR              Q+   LQD+  E   + E   ER++  
Sbjct: 503 VEAAQETVADYQQTIKKYR--------------QLTAHLQDVNRELTNQQEASVERQQQP 548

Query: 246 SPE 248
            PE
Sbjct: 549 PPE 551



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 82/340 (24%), Positives = 131/340 (38%), Gaps = 88/340 (25%)

Query: 103 TELVGSPGKHQHQEEGNVTVRPFP-RPQSL-------DLGATFTVDAHQLDNQSQPRDPG 154
           ++L G   K         T RP P RP S         LG + +  A +L + S+P  P 
Sbjct: 129 SKLRGLKPKKAPTARKTTTRRPKPTRPASTGVAGASSSLGPSGSASAGELSS-SEPSTPA 187

Query: 155 ---------PQSAFSLPGSTQHLRSQLSQ---CKQRYQDLQEKL---LLSEATVFAQANE 199
                    P    + PG+   L S   +    + + +DL+EKL    L  A   A+  E
Sbjct: 188 QTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKE 247

Query: 200 LEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPEC---------- 249
           LEK+++ L      K   ++ Q DLQ    E    ++   E +E    E           
Sbjct: 248 LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMA 307

Query: 250 ---------------EEHNSLKEMV--------LMEGLCSEQGRRGSTLASSSERKPLEN 286
                          +E  +LKE V        +++    E+G  G+  ASS + K LE 
Sbjct: 308 TLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGA--ASSYQLKQLEE 365

Query: 287 QLG----------------KQEEFRVY----GKSENILVLRKDIKDLKAQLQNANKVIQN 326
           Q                  KQE  ++      K++ + V+R+  + L+ +L  A   I  
Sbjct: 366 QNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 425

Query: 327 LKSRV-------RSLSVTSDYSSSL-ERPRKLR-AVGTLE 357
           LK +V         + + +D + +L E+ R+LR  VG LE
Sbjct: 426 LKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLE 465


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 86/427 (20%), Positives = 170/427 (39%), Gaps = 91/427 (21%)

Query: 1    MLSLCLENAELKEQMGETMSDGWEIEEDKEKGEVMVETV---VTKEGLSESSLQAEFRKL 57
            +L+L  + A+ K+++ + +     +EE K+K     E +   + ++ L+   L+    +L
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425

Query: 58   QGKLKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEE 117
            Q +L +    ++L  ++ V S+ E   K   +LL    S   R   E   +  + + +E 
Sbjct: 1426 QQELDDL--TVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKET 1483

Query: 118  GNVTVRPFPRPQSLDLGATFTVDAHQL-----DNQSQPRDPGPQSAFSLPGSTQHLRSQL 172
              +++      ++L+    F     QL     D  S   D G ++   L  S + L  Q+
Sbjct: 1484 KALSLAR-ALEEALEAKEEFERQNKQLRADMEDLMSSKDDVG-KNVHELEKSKRALEQQV 1541

Query: 173  SQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETC 232
             + + + ++L+++L         QA E  K R+ +  +++  Q  + +Q           
Sbjct: 1542 EEMRTQLEELEDEL---------QATEDAKLRLEVNMQAMKAQFERDLQT---------- 1582

Query: 233  GRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQE 292
             R E   E++     +  E  +  E+        E  R+   LA +S++K          
Sbjct: 1583 -RDEQNEEKKRLLIKQVRELEA--EL--------EDERKQRALAVASKKK---------- 1621

Query: 293  EFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSV-TSDYSSSLERPRKLR 351
                         +  D+KDL+AQ++ ANK    +  ++R L     DY   LE  R  R
Sbjct: 1622 -------------MEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASR 1668

Query: 352  AVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEE 411
                          DE            ++   +++K L+SL   + QL+ +L  +    
Sbjct: 1669 --------------DE-----------IFAQSKESEKKLKSLEAEILQLQEELASSERAR 1703

Query: 412  KLAEELR 418
            + AE+ R
Sbjct: 1704 RHAEQER 1710


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 86/452 (19%), Positives = 180/452 (39%), Gaps = 61/452 (13%)

Query: 8    NAELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNI 67
            + +LK+   E  S   ++EE++E    + + + T      + ++ +     G L+ A  +
Sbjct: 1328 STKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHA-QVADMKKKMEDSVGCLETAEEV 1386

Query: 68   INLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPR 127
               L++ L   S+    K+     +  T T  +   + +     HQ Q   N+  +    
Sbjct: 1387 KRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKF 1446

Query: 128  PQSL----DLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQ 183
             Q L     + A +  +  + + +++ ++    S           +++L +  ++++   
Sbjct: 1447 DQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEM 1506

Query: 184  EKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREE 243
            E L+ S+  V    +ELEK +  L      +Q  ++++  L++L          E E + 
Sbjct: 1507 EDLMSSKDDVGKSVHELEKSKRAL------EQQVEEMKTQLEEL----------EDELQA 1550

Query: 244  TTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQE-EFRVYGKSEN 302
            T   +     +L+ M        E+  +G    S  ++K L  Q+ + E E     K  +
Sbjct: 1551 TEDAKLRLEVNLQAMKAQ----FERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRS 1606

Query: 303  ILV-----LRKDIKDLKAQLQNAN-----------KVIQNLKSRVRSLSVT-----SDYS 341
            + V     L  D+KDL+A + +AN           K+   +K  +R L  T        +
Sbjct: 1607 MAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILA 1666

Query: 342  SSLERPRKLRA-----------VGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDL 390
             + E  +KL++           +   E +   +  + DE  L+D        G  A ++ 
Sbjct: 1667 QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDE--LADEIANSSGKGALALEEK 1724

Query: 391  ESLIQRVSQLEAQL-PKNGLEEKLAEELRSAS 421
              L  R++QLE +L  + G  E + + L+ A+
Sbjct: 1725 RRLEARIAQLEEELEEEQGNTELINDRLKKAN 1756



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 46/214 (21%), Positives = 94/214 (43%), Gaps = 32/214 (14%)

Query: 166  QHLRSQLSQCKQRYQDLQE----------KLLLSEATVFAQANELEKYRVMLTGESLVKQ 215
            QHL+++  + +Q  Q+L+E          KL L + T  A+  +LE+ +++L  ++    
Sbjct: 932  QHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLA 991

Query: 216  DSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEMV--LMEGLCSEQGRR-- 271
              K++  D           + N  E EE +    +  N  + M+  L E L  E+ +R  
Sbjct: 992  KEKKLLED------RIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQE 1045

Query: 272  ---------GSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANK 322
                     G +   S +   L+ Q+  + + ++  K E +      +++  AQ   A K
Sbjct: 1046 LEKTRRKLEGDSTDLSDQIAELQAQIA-ELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104

Query: 323  VIQNLKSRVRSL--SVTSDYSSSLERPRKLRAVG 354
             I+ L+S++  L   + S+ +S  +  ++ R +G
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLG 1138


>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 43/201 (21%), Positives = 91/201 (45%), Gaps = 23/201 (11%)

Query: 7   ENAELKEQMGETMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHN 66
           E   L + + + +S   E +ED+++ +V VE     E + ESS   E +K +       +
Sbjct: 150 EGCRLAQHLVQKLSP--ENDEDEDE-DVQVEEA---EKVLESSAPREVQKAEESKVPEDS 203

Query: 67  IINLLKEQLVLSSKEGNSKLT---PELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVR 123
           +     E+  ++    +       P   + +T   + +N+ LV        + +  + + 
Sbjct: 204 L-----EECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNIL 258

Query: 124 PFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQ 183
           P P P S     +  V A  L ++        ++  ++    + LR QL++ KQ++++L+
Sbjct: 259 PVPGPTSSATNVSMVVSAGPLSSE--------KAEMNILEINEKLRPQLAEKKQQFRNLK 310

Query: 184 EKLLLSEATVFAQANELEKYR 204
           EK  L++ + F  AN+ +KY+
Sbjct: 311 EKCFLTQLSGFL-ANQQKKYK 330



 Score = 32.3 bits (72), Expect = 0.84
 Identities = 53/210 (25%), Positives = 85/210 (40%), Gaps = 45/210 (21%)

Query: 168 LRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDL 227
           LR QL++ KQ++++L+EK  L++   F  AN  +KY+                       
Sbjct: 24  LRPQLAEKKQQFRNLKEKCFLTQLAGFL-ANRQKKYK----------------------- 59

Query: 228 GYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERK--PLE 285
            YE C        R E    E +    LK+        +E+ R+   L  S ER+   L 
Sbjct: 60  -YEECKDLIKFMLRNERQFKEEKLAEQLKQ--------AEELRQYKVLVHSQERELTQLR 110

Query: 286 NQL--GKQEEFRVYGKSENILVLRKDIK----DLKAQLQNANKVIQNLKSRVRSLSVTSD 339
            +L  G+     +Y   + +L   +  K    DL+ QL    ++ Q+L   V+ LS  +D
Sbjct: 111 EKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHL---VQKLSPEND 167

Query: 340 YSSSLERPRKLRAVGTLEGSSPHSVPDEDE 369
                E  +   A   LE S+P  V   +E
Sbjct: 168 EDED-EDVQVEEAEKVLESSAPREVQKAEE 196


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 88/418 (21%), Positives = 167/418 (39%), Gaps = 65/418 (15%)

Query: 28  DKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNI-INLLKEQLVLSSKEGNSKL 86
           +KEK  V+       + ++ES  +AE  +L+ +L  +H   ++ LKE L +  +    KL
Sbjct: 604 EKEKNAVL-------DRMAESQ-EAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKL 655

Query: 87  TPELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPRPQSLDLGATFTVDAHQLDN 146
              L +H    I+ +  E+       Q +++  +T     +   L L  +   D  Q   
Sbjct: 656 KDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLIT-----KQNQLILEISKLKDLQQSLV 710

Query: 147 QSQPRDPGPQSAFSLPGSTQHLRSQLSQ---CKQRYQDLQEKLLLSEATVFAQANELEKY 203
            S+  +   Q    L    + LR +  +    +Q  Q+LQ K  L E  +  + N+L++ 
Sbjct: 711 NSKSEEMTLQIN-ELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEK 769

Query: 204 RVMLTGESLVKQDSKQIQVDLQDLG-----------YETCGRSENEAEREETTSPECEEH 252
              L  E+ + +D K+   D+  +             ++      ++  E+      EE+
Sbjct: 770 FAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEEN 829

Query: 253 NSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKD 312
             LK+  +     +E+  +     S +E+    N    QEE+        +L ++ D++D
Sbjct: 830 EDLKQQCIQ---LNEEIEKQRNTFSFAEKNFEVNYQELQEEYAC------LLKVKDDLED 880

Query: 313 LKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSSPHSVPDEDEGWL 372
            K      NK     KS++++L+              L+ +         SV DED+ ++
Sbjct: 881 SK------NKQELEYKSKLKALN----------EELHLQRINPTTVKMKSSVFDEDKTFV 924

Query: 373 SD----------GTGAFYSPGLQAKKDLESLIQRVSQLEAQL-PKNGLEEKLAEELRS 419
           ++           T          K++   L QR+S L  QL  K+G    L EE++S
Sbjct: 925 AETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKS 982


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 88/418 (21%), Positives = 167/418 (39%), Gaps = 65/418 (15%)

Query: 28  DKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNI-INLLKEQLVLSSKEGNSKL 86
           +KEK  V+       + ++ES  +AE  +L+ +L  +H   ++ LKE L +  +    KL
Sbjct: 604 EKEKNAVL-------DRMAESQ-EAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKL 655

Query: 87  TPELLVHLTSTIERINTELVGSPGKHQHQEEGNVTVRPFPRPQSLDLGATFTVDAHQLDN 146
              L +H    I+ +  E+       Q +++  +T     +   L L  +   D  Q   
Sbjct: 656 KDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLIT-----KQNQLILEISKLKDLQQSLV 710

Query: 147 QSQPRDPGPQSAFSLPGSTQHLRSQLSQ---CKQRYQDLQEKLLLSEATVFAQANELEKY 203
            S+  +   Q    L    + LR +  +    +Q  Q+LQ K  L E  +  + N+L++ 
Sbjct: 711 NSKSEEMTLQIN-ELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEK 769

Query: 204 RVMLTGESLVKQDSKQIQVDLQDLG-----------YETCGRSENEAEREETTSPECEEH 252
              L  E+ + +D K+   D+  +             ++      ++  E+      EE+
Sbjct: 770 FAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEEN 829

Query: 253 NSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKD 312
             LK+  +     +E+  +     S +E+    N    QEE+        +L ++ D++D
Sbjct: 830 EDLKQQCIQ---LNEEIEKQRNTFSFAEKNFEVNYQELQEEYAC------LLKVKDDLED 880

Query: 313 LKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSSPHSVPDEDEGWL 372
            K      NK     KS++++L+              L+ +         SV DED+ ++
Sbjct: 881 SK------NKQELEYKSKLKALN----------EELHLQRINPTTVKMKSSVFDEDKTFV 924

Query: 373 SD----------GTGAFYSPGLQAKKDLESLIQRVSQLEAQL-PKNGLEEKLAEELRS 419
           ++           T          K++   L QR+S L  QL  K+G    L EE++S
Sbjct: 925 AETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKS 982


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.127    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,052,000
Number of Sequences: 37866
Number of extensions: 748536
Number of successful extensions: 3197
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 213
Number of HSP's that attempted gapping in prelim test: 2942
Number of HSP's gapped (non-prelim): 450
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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