Search of human proteins with 169211440

Search of human proteins with 169211440

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
         (452 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po...   904   0.0  
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi...   893   0.0  
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]    395   e-110
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi...   367   e-101
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]   364   e-100
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi...   333   1e-91
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi...   311   6e-85
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi...   305   4e-83
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi...   272   4e-73
gi|166851804 tudor domain containing 9 [Homo sapiens]                 228   1e-59
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ...   216   4e-56
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ...   216   4e-56
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1...   208   7e-54
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2...   201   1e-51
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom...   192   4e-49
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi...   185   8e-47
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi...   169   4e-42
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo...   169   6e-42
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi...   152   8e-37
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ...   136   4e-32
gi|38505213 YTH domain containing 2 [Homo sapiens]                    132   6e-31
gi|13129006 nucleolar protein GU2 [Homo sapiens]                       31   2.0  
gi|110349719 titin isoform N2-A [Homo sapiens]                         30   3.4  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      30   3.4  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      30   3.4  
gi|110349715 titin isoform N2-B [Homo sapiens]                         30   3.4  
gi|19923796 NMD3 homolog [Homo sapiens]                                30   5.9  
gi|195927059 axin 2 [Homo sapiens]                                     29   7.7  
gi|31543667 suppressor of var1, 3-like 1 [Homo sapiens]                29   7.7  

>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
           polypeptide 40 [Homo sapiens]
          Length = 452

 Score =  904 bits (2337), Expect = 0.0
 Identities = 452/452 (100%), Positives = 452/452 (100%)

Query: 1   MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 60
           MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK
Sbjct: 1   MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 60

Query: 61  KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 120
           KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE
Sbjct: 61  KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 120

Query: 121 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 180
           EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL
Sbjct: 121 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 180

Query: 181 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 240
           TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK
Sbjct: 181 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 240

Query: 241 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 300
           FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD
Sbjct: 241 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 300

Query: 301 YDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 360
           YDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV
Sbjct: 301 YDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 360

Query: 361 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 420
           VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD
Sbjct: 361 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 420

Query: 421 HVIPEIKRTSLTSVVLTLKCLAIHDVIRYVDN 452
           HVIPEIKRTSLTSVVLTLKCLAIHDVIRYVDN
Sbjct: 421 HVIPEIKRTSLTSVVLTLKCLAIHDVIRYVDN 452


>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo
           sapiens]
          Length = 779

 Score =  893 bits (2308), Expect = 0.0
 Identities = 446/449 (99%), Positives = 448/449 (99%)

Query: 1   MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 60
           MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK
Sbjct: 1   MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 60

Query: 61  KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 120
           KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE
Sbjct: 61  KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 120

Query: 121 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 180
           EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL
Sbjct: 121 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 180

Query: 181 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 240
           TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK
Sbjct: 181 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 240

Query: 241 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 300
           FCNLIGPRDRENTAYIQAIV+VTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD
Sbjct: 241 FCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 300

Query: 301 YDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 360
           YDYDVQDT LDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV
Sbjct: 301 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 360

Query: 361 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 420
           VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD
Sbjct: 361 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 420

Query: 421 HVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
           HVIPEIKRTSLTSVVLTLKCLAIHDVIR+
Sbjct: 421 HVIPEIKRTSLTSVVLTLKCLAIHDVIRF 449


>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
          Length = 1220

 Score =  395 bits (1015), Expect = e-110
 Identities = 204/398 (51%), Positives = 279/398 (70%), Gaps = 18/398 (4%)

Query: 52  TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAA 111
           + PI K +++++QAV DN  LIV G TGSGKTTQ+ +YL EAG++  G IG TQPR+VAA
Sbjct: 564 SLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAA 623

Query: 112 ISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVII 171
           +SVA+RV+EE  C LG +VGY +RF+DC+S ET IKYMTDG LL+  L DP+LT++++I+
Sbjct: 624 MSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIM 683

Query: 172 LDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIP 231
           LDEAHERT+ TD+LFGLLKK  Q     +++ +K++V SAT++  K S +F   PIF IP
Sbjct: 684 LDEAHERTIHTDVLFGLLKKTVQ-----KRQDMKLIVTSATLDAVKFSQYFYEAPIFTIP 738

Query: 232 GRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCEL 291
           GR YPV   +           T Y+ A +   M IHL E  GDILVFLTGQ EI+ +CE+
Sbjct: 739 GRTYPVEILYTK------EPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEI 792

Query: 292 LFQMAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATS 351
           L++  +S+  D       +  L+ILP Y ++ ++ Q RIF P PPG RK VI+TNI+ TS
Sbjct: 793 LYERMKSLGPD-------VPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETS 845

Query: 352 LTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSK 411
           LTIDGI YVVD GFVKQ  +N + G+D L V PIS+++A QR+GRAGRT  GKC+R+Y++
Sbjct: 846 LTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTE 905

Query: 412 DFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
             +   M    +PEI+RT+L S VL+LK + I+D++ +
Sbjct: 906 RAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSF 943


>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo
           sapiens]
          Length = 1227

 Score =  367 bits (942), Expect = e-101
 Identities = 185/396 (46%), Positives = 273/396 (68%), Gaps = 19/396 (4%)

Query: 54  PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAIS 113
           PI   +++++  +RDNS +IV G TGSGKTTQL +YL+E G++ +GMIG TQPR+VAA+S
Sbjct: 533 PIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMS 592

Query: 114 VAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILD 173
           VA+RV+EEM   LG +VGY +RF+DC+S+ T IKYMTDG LL+  L + +L  +S II+D
Sbjct: 593 VAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMD 652

Query: 174 EAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGR 233
           EAHER+L TD+LFGLL+++       R+  LK++V SATM+  K +AFFGN PIF IPGR
Sbjct: 653 EAHERSLNTDVLFGLLREVVA-----RRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGR 707

Query: 234 LYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLF 293
            +PV   F     P++     Y++A VK ++ +HL+   GDIL+F+ GQ +IE + + + 
Sbjct: 708 TFPVDILFSKT--PQE----DYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIV 761

Query: 294 QMAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLT 353
           +  E ++            L +LP Y  + +D Q +IF   P G+RKC+++TNI+ TSLT
Sbjct: 762 EHLEELEN--------APALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLT 813

Query: 354 IDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDF 413
           +DGI +V+D G+ K    NPR+G+D L++ PIS++ A QRSGRAGRT  G+CFR+Y++  
Sbjct: 814 VDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSA 873

Query: 414 WNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
           +   +    +PEI+RT+L +VVL LK L + D++++
Sbjct: 874 YKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQF 909


>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
          Length = 1041

 Score =  364 bits (934), Expect = e-100
 Identities = 193/400 (48%), Positives = 271/400 (67%), Gaps = 22/400 (5%)

Query: 51  PTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM-IGVTQPRKV 109
           P FP    R++++ A+ ++  LI+ G TGSGKTTQ+P+YL+E G++  GM I  TQPR+V
Sbjct: 400 PVFPF---REELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRV 456

Query: 110 AAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSV 169
           AA+SVA RVA EM   LG++VGY +RF+DC+S+ T ++YMTDG LL+  L +P+L  +SV
Sbjct: 457 AAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSV 516

Query: 170 IILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFD 229
           +++DEAHERTL TDILFGL+K +        +  LKV+V SATM+ A+ S FF + P+F 
Sbjct: 517 VMVDEAHERTLHTDILFGLIKDV-----ARFRPELKVLVASATMDTARFSTFFDDAPVFR 571

Query: 230 IPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSC 289
           IPGR +PV + F       D     Y++A V   + IH+ +  GDILVFLTGQ EIE +C
Sbjct: 572 IPGRRFPV-DIFYTKAPEAD-----YLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAAC 625

Query: 290 ELLFQMAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISA 349
           E+L      +        + +  LL+LP Y ++ +D Q RIF P PPG RK V++TNI+ 
Sbjct: 626 EMLQDPCRRL-------GSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAE 678

Query: 350 TSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIY 409
           TS TI+GI YV+D GF KQ ++NPR G++ L V P SK+ A QR+GRAGR ++GKCFR+Y
Sbjct: 679 TSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLY 738

Query: 410 SKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
           +   +   + +  +PEI+RTSL +VVL LK L IHD++ +
Sbjct: 739 TAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHF 778


>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
           sapiens]
          Length = 795

 Score =  333 bits (855), Expect = 1e-91
 Identities = 191/394 (48%), Positives = 261/394 (66%), Gaps = 29/394 (7%)

Query: 66  VRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM---IGVTQPRKVAAISVAQRVAEEM 122
           VR  SF++V G TGSGKTTQ+P++  E   S  G    +  TQPR+VAA+SVAQRVA+EM
Sbjct: 151 VRHQSFVLV-GETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEM 209

Query: 123 KCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTT 182
              LG +VGY +RF+DCSS +T +KYMTDG LL+  + DP L ++ VIILDEAHERTL T
Sbjct: 210 DVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLAT 269

Query: 183 DILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFC 242
           DIL G+LK++ +++S      LKV+VMSAT++  K   +F NCP+  IPGR +PV E F 
Sbjct: 270 DILMGVLKEVVRQRS-----DLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPV-EIFY 323

Query: 243 NLIGPRDRENTAYIQAIVKVTMDIHL-NEMAGDILVFLTGQFEIEKSCELLFQMAESVDY 301
                RD     Y++A ++  + IH+  E  GD+L+FLTGQ EI+++C+ +    E  D 
Sbjct: 324 TPEPERD-----YLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRI--KREVDDL 376

Query: 302 DYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGI------RKCVISTNISATSLTID 355
             +V D     + I+P Y ++   QQ+RIF PPPP        RK V+STNI+ TSLTID
Sbjct: 377 GPEVGD-----IKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTID 431

Query: 356 GIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWN 415
           G+ +V+D GF KQ  +NPR+ ++ L V  ISK+ A QR+GRAGRT  GKCFR+Y++  + 
Sbjct: 432 GVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYK 491

Query: 416 QCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
             M D+  PEI R++L SVVL LK L I D++ +
Sbjct: 492 TEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHF 525


>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo
           sapiens]
          Length = 707

 Score =  311 bits (798), Expect = 6e-85
 Identities = 174/405 (42%), Positives = 254/405 (62%), Gaps = 27/405 (6%)

Query: 52  TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAA 111
           + PI + R +++  +R+    ++ G TGSGKTTQ+P+YLYE G S+ G+I VTQPR+VAA
Sbjct: 73  SLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQGIIAVTQPRRVAA 132

Query: 112 ISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVII 171
           IS+A RV++E +  LG  VGY VRFDD +S++T IK++TDG LL+  + D  L K+S +I
Sbjct: 133 ISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKFLTDGMLLREAISDSLLRKYSCVI 192

Query: 172 LDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIP 231
           LDEAHERT+ TD+LFG++K   + +    K  LKV+VMSATM++   S +F   P+  + 
Sbjct: 193 LDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNGAPVLYLE 252

Query: 232 GRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAG-DILVFLTGQFEIE---K 287
           GR +P++  +        +    Y+ A +     IH    +  DILVFLTGQ EIE   K
Sbjct: 253 GRQHPIQVFYTK------QPQNDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEIEAMSK 306

Query: 288 SCELLFQMAESVDYDYDVQDTILDG---LLILPCYGSMTTDQQRRIFLPPPPGIRKCVIS 344
           +C              D+   + DG   +L+LP Y S+   QQ R+F   P G RK +IS
Sbjct: 307 TCR-------------DIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIIS 353

Query: 345 TNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGK 404
           TNI+ TS+TI GI+YVVD G VK   +NP  GL++L V  +SK++A QR+GRAGR  SG 
Sbjct: 354 TNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGI 413

Query: 405 CFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
           C+R+Y++D + +      +PEI+R +L SV+L L  + + +V+ +
Sbjct: 414 CYRLYTEDEFEK-FDKMTVPEIQRCNLASVMLQLLAMKVPNVLTF 457


>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
           sapiens]
          Length = 703

 Score =  305 bits (782), Expect = 4e-83
 Identities = 171/439 (38%), Positives = 268/439 (61%), Gaps = 44/439 (10%)

Query: 38  EEKGCTSQEGGTTPTF---------------PIQKQRKKIIQAVRDNSFLIVTGNTGSGK 82
           EE+   ++  GTT  +               P+ K R  I+  + +   +++ G TG GK
Sbjct: 24  EERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGK 83

Query: 83  TTQLPKYLYEAGFSQHG-MIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSS 141
           +TQ+P+YL EAG++  G ++GVTQPR+VAA++VA RVAEE    LG +VGY +RFDDC+ 
Sbjct: 84  STQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTD 143

Query: 142 K-ETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNR 200
           +  T IK++TDG L++ ++ DP LTK+SVI+LDEAHERTL TDI  GLLKK+ +++    
Sbjct: 144 QLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGD-- 201

Query: 201 KEHLKVVVMSATMELAKLSAFFGN----------CPIFDIPGRLYPVREKFCNLIGPRDR 250
              L+++V SAT++  K   FF            C I  + GR +PV   +     P   
Sbjct: 202 ---LRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPD-- 256

Query: 251 ENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTIL 310
               YI++ V+  + IH  E  GD+L FLTGQ E+E    +L + A ++      +  + 
Sbjct: 257 ----YIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARAL-----ARTGMK 307

Query: 311 DGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLN 370
             L +LP Y  + + +Q ++F      +RK +++TN++ TS+TI GI YV+D GFVK   
Sbjct: 308 RHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRA 367

Query: 371 HNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTS 430
           +NPR  ++ L VVP+S++ A QR+GR GR+ SGKC+R+Y+++ +++ +P   +PE++R++
Sbjct: 368 YNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDK-LPQSTVPEMQRSN 426

Query: 431 LTSVVLTLKCLAIHDVIRY 449
           L  V+L LK L I +V+R+
Sbjct: 427 LAPVILQLKALGIDNVLRF 445


>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
           sapiens]
          Length = 1143

 Score =  272 bits (696), Expect = 4e-73
 Identities = 159/441 (36%), Positives = 257/441 (58%), Gaps = 33/441 (7%)

Query: 14  RQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLI 73
           R    ER  + +   L  +    ++  G  ++        PI +   +I+Q ++++  ++
Sbjct: 123 RHLPAERVAEFRRALLHYLDFGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVV 182

Query: 74  VTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQ 133
           V G+TG GK+TQ+P+YL  AGFS    +  TQPR++A IS+A+RV  E     GS+VGYQ
Sbjct: 183 VAGDTGCGKSTQVPQYLLAAGFSH---VACTQPRRIACISLAKRVGFESLSQYGSQVGYQ 239

Query: 134 VRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLF 193
           +RF+   S  T I ++T G LL+ I  +P+L ++ V+I+DE HER L  D L G+L++L 
Sbjct: 240 IRFESTRSAATKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLL 299

Query: 194 QEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENT 253
               P R + LKV++MSAT+ ++  S++F N P+  +PGRL+P+   +     P++ E T
Sbjct: 300 ----PTRPD-LKVILMSATINISLFSSYFSNAPVVQVPGRLFPITVVY----QPQEAEPT 350

Query: 254 AYI------QAIVKVTMDI---HLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYD 304
                    +  ++V   I   +  E  GD+LVFL+G  EI    E     A        
Sbjct: 351 TSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVFLSGMAEISAVLEAAQTYASHTQR--- 407

Query: 305 VQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGG 364
                    ++LP + +++   Q ++F   PPG+RKC++STNI+ TS+TIDGIR+VVD G
Sbjct: 408 --------WVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSG 459

Query: 365 FVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIP 424
            VK+++++P+  L  L+   IS++ A QR GRAGRT  G CFR+Y++  ++   P + +P
Sbjct: 460 KVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAP-YPVP 518

Query: 425 EIKRTSLTSVVLTLKCLAIHD 445
           EI+R +L S+VL +K +++ D
Sbjct: 519 EIRRVALDSLVLQMKSMSVGD 539


>gi|166851804 tudor domain containing 9 [Homo sapiens]
          Length = 1382

 Score =  228 bits (580), Expect = 1e-59
 Identities = 143/424 (33%), Positives = 236/424 (55%), Gaps = 36/424 (8%)

Query: 48  GTT---PTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYE--AGFSQHGMIG 102
           GTT   P  PI + +++++  +  NS +I+ G TGSGK+TQLP+Y+ +     S +  I 
Sbjct: 124 GTTYKYPDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIV 183

Query: 103 VTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDP 162
           VTQPRK+ A S+A+ +++E   TLG  VGYQV  +  ++++T + YMT G LL+ I+   
Sbjct: 184 VTQPRKIGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAK 243

Query: 163 NLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFF 222
           +L +F+ II+DE HERT   D L  +++KL +  S      +KVV+MSAT+   + + +F
Sbjct: 244 SLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNS----RFVKVVLMSATISCKEFADYF 299

Query: 223 G--------NCPIFDIPGRLYPVREKFCN--------LIGPRDRENTAYIQAIVKVTMDI 266
                       IF++ G+ + V E + N         + P   E     + I +V   +
Sbjct: 300 AVPVQNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVA--V 357

Query: 267 HLNEMAGDILVFLTG-------QFEIEKSCELLFQMA-ESVDYDYDVQDTILDGLL-ILP 317
            L +M  D+ +  +G       QF +E+S  L+F      ++Y +++  +++   L + P
Sbjct: 358 SLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHKRLQVYP 417

Query: 318 CYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGL 377
            + S+  ++Q  +FL P PG RK ++STNI+ +S+T+  ++YV+D    + L  +     
Sbjct: 418 LHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNY 477

Query: 378 DILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLT 437
             L +   SK+   QR GRAGR S G C+R+  KDFW+  +PDHV+PE+ R  L S +L 
Sbjct: 478 QSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILK 537

Query: 438 LKCL 441
           +K L
Sbjct: 538 VKLL 541


>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2
           [Homo sapiens]
          Length = 1155

 Score =  216 bits (549), Expect = 4e-56
 Identities = 145/437 (33%), Positives = 232/437 (53%), Gaps = 39/437 (8%)

Query: 23  DLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGK 82
           + +E RLS   +     +G   QE    P  P+   R  I+ A+  +  ++++G+TG GK
Sbjct: 368 EAEEVRLSQSLLELWRRRGPVWQEA---PQLPVDPHRDTILNAIEQHPVVVISGDTGCGK 424

Query: 83  TTQLPKYLYEA----GFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD 138
           TT++P+ L E     G      + +TQPR+++A+SVAQRV+ E+  +L   VG+QVR + 
Sbjct: 425 TTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLES 484

Query: 139 CS-SKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKS 197
              S+  A+ + T G LL+ +  +P+L   S +I+DE HER + TD L  LLK L Q  +
Sbjct: 485 KPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGL-QRLN 543

Query: 198 PNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPR--------- 248
           P     L++V+MSAT +  + S +FG CP+  +PG +YPV+E +   I  +         
Sbjct: 544 PA----LRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHR 599

Query: 249 ------DRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYD 302
                 + E    +  +  + + I      G IL FL G  EI+   + L +     +  
Sbjct: 600 HRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESK 659

Query: 303 YDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVD 362
           Y          LILP + ++    Q+ IF  PP G+RK V++TNI+ TS+TI+ I +VVD
Sbjct: 660 Y----------LILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVD 709

Query: 363 GGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHV 422
            G  K+  ++ +  +  LE V +S++  +QR GRAGR  SG  + ++ +    + +P  V
Sbjct: 710 SGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQV 769

Query: 423 IPEIKRTSLTSVVLTLK 439
            PEI RT L ++VL  K
Sbjct: 770 -PEILRTPLENLVLQAK 785


>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1
           [Homo sapiens]
          Length = 1194

 Score =  216 bits (549), Expect = 4e-56
 Identities = 145/437 (33%), Positives = 232/437 (53%), Gaps = 39/437 (8%)

Query: 23  DLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGK 82
           + +E RLS   +     +G   QE    P  P+   R  I+ A+  +  ++++G+TG GK
Sbjct: 407 EAEEVRLSQSLLELWRRRGPVWQEA---PQLPVDPHRDTILNAIEQHPVVVISGDTGCGK 463

Query: 83  TTQLPKYLYEA----GFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD 138
           TT++P+ L E     G      + +TQPR+++A+SVAQRV+ E+  +L   VG+QVR + 
Sbjct: 464 TTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLES 523

Query: 139 CS-SKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKS 197
              S+  A+ + T G LL+ +  +P+L   S +I+DE HER + TD L  LLK L Q  +
Sbjct: 524 KPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGL-QRLN 582

Query: 198 PNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPR--------- 248
           P     L++V+MSAT +  + S +FG CP+  +PG +YPV+E +   I  +         
Sbjct: 583 PA----LRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHR 638

Query: 249 ------DRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYD 302
                 + E    +  +  + + I      G IL FL G  EI+   + L +     +  
Sbjct: 639 HRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESK 698

Query: 303 YDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVD 362
           Y          LILP + ++    Q+ IF  PP G+RK V++TNI+ TS+TI+ I +VVD
Sbjct: 699 Y----------LILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVD 748

Query: 363 GGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHV 422
            G  K+  ++ +  +  LE V +S++  +QR GRAGR  SG  + ++ +    + +P  V
Sbjct: 749 SGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQV 808

Query: 423 IPEIKRTSLTSVVLTLK 439
            PEI RT L ++VL  K
Sbjct: 809 -PEILRTPLENLVLQAK 824


>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
           [Homo sapiens]
          Length = 1008

 Score =  208 bits (530), Expect = 7e-54
 Identities = 138/454 (30%), Positives = 223/454 (49%), Gaps = 63/454 (13%)

Query: 54  PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLY----EAGFSQHGMIGVTQPRKV 109
           P    +K+++  + ++   +++G TG GKTTQ+ +++     E G      I  TQPR++
Sbjct: 208 PSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRI 267

Query: 110 AAISVAQRVAEEM--KCTLGSKVGYQVRFDD-CSSKETAIKYMTDGCLLKHILGDPNLTK 166
           +AISVA+RVA E    C  G+  GYQ+R       K+ +I Y T G +L+ +  DP L+ 
Sbjct: 268 SAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSS 327

Query: 167 FSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCP 226
            S I+LDE HER L +D+L  ++K L      N +  LKV++MSAT+   K S +FGNCP
Sbjct: 328 VSHIVLDEIHERNLQSDVLMTVVKDLL-----NFRSDLKVILMSATLNAEKFSEYFGNCP 382

Query: 227 IFDIPGRLYPVREKFCN-----------------------LIGPRDRENTAYIQAIVKVT 263
           +  IPG  +PV E                           + G  +R+     +AI K  
Sbjct: 383 MIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKER 442

Query: 264 MDIHLNEMAG--------------------DILVFLTGQFEIEKSCELLFQMAESVDYDY 303
              ++ E+                      +++V L     +E+    +       D   
Sbjct: 443 WPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNIS 502

Query: 304 DVQDTIL-------DGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDG 356
            + D ++       D  LI+P +  M T  Q ++F   PPG+RK VI+TNI+ TS+TID 
Sbjct: 503 TLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDD 562

Query: 357 IRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQ 416
           + YV+DGG +K+ + + +  +  +    +SK+ A QR GRAGR   G C+ +Y+      
Sbjct: 563 VVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYN-GLRAS 621

Query: 417 CMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRYV 450
            + D+ +PEI RT L  + L +K L +  +  ++
Sbjct: 622 LLDDYQLPEILRTPLEELCLQIKILRLGGIAYFL 655


>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
           [Homo sapiens]
          Length = 994

 Score =  201 bits (510), Expect = 1e-51
 Identities = 139/442 (31%), Positives = 225/442 (50%), Gaps = 53/442 (11%)

Query: 54  PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLY----EAGFSQHGMIGVTQPRKV 109
           P    +K+++  + ++   +++G TG GKTTQ+ +++     E G      I  TQPR++
Sbjct: 208 PSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRI 267

Query: 110 AAISVAQRVAEEM--KCTLGSKVGYQVRFDD-CSSKETAIKYMTDGCLLKHILGDPNLTK 166
           +AISVA+RVA E    C  G+  GYQ+R       K+ +I Y T G +L+ +  DP L+ 
Sbjct: 268 SAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSS 327

Query: 167 FSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCP 226
            S I+LDE HER L +D+L  ++K L      N +  LKV++MSAT+   K S +FGNCP
Sbjct: 328 VSHIVLDEIHERNLQSDVLMTVVKDLL-----NFRSDLKVILMSATLNAEKFSEYFGNCP 382

Query: 227 IFDIPGRLYPVREKFCNLIGPRDR---ENTAYIQAIVKVTMDIHLN------------EM 271
           +  IPG  +PV E     +  + R   E   +     +  M  H+N            E 
Sbjct: 383 MIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKER 442

Query: 272 AGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTIL--------DG--LLILPCYGS 321
             D +  L  ++    S   + +M E    D ++   ++        DG  L+ LP + +
Sbjct: 443 WPDYVRELRRRY--SASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDN 500

Query: 322 MTT-------------DQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQ 368
           ++T               Q ++F   PPG+RK VI+TNI+ TS+TID + YV+DGG +K+
Sbjct: 501 ISTLHDLLMSQVMFKSVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKE 560

Query: 369 LNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKR 428
            + + +  +  +    +SK+ A QR GRAGR   G C+ +Y+       + D+ +PEI R
Sbjct: 561 THFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYN-GLRASLLDDYQLPEILR 619

Query: 429 TSLTSVVLTLKCLAIHDVIRYV 450
           T L  + L +K L +  +  ++
Sbjct: 620 TPLEELCLQIKILRLGGIAYFL 641


>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
           sapiens]
          Length = 743

 Score =  192 bits (489), Expect = 4e-49
 Identities = 129/450 (28%), Positives = 243/450 (54%), Gaps = 39/450 (8%)

Query: 4   FPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKII 63
           FP     +   +EE     DL+      +  + R  K    +E       PI K++   +
Sbjct: 18  FPESLDSSDGDEEEVLACEDLELNPFDGLPYSSRYYKLLKERED-----LPIWKEKYSFM 72

Query: 64  QAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFS---QHGMIGVTQPRKVAAISVAQRVAE 120
           + +  N  +IV+G+   GK+ Q+P++  E   S   QHG +  TQ  K   + +A RVA+
Sbjct: 73  ENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVAD 132

Query: 121 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 180
           EM   +G +VGY + F++C + ET ++Y TD  L + ++ +P L  + VIILD+ HER++
Sbjct: 133 EMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSI 192

Query: 181 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 240
            TD+L GLLK +        +  LK+++ S+   ++KL++++GN P+ ++  + +PV   
Sbjct: 193 ATDVLLGLLKDVLL-----ARPELKLIINSSPHLISKLNSYYGNVPVIEVKNK-HPVEVV 246

Query: 241 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 300
           + +     + +  ++ ++I+++  +IH +   GDI+VFL  + +IEK CE ++Q   +++
Sbjct: 247 YLS-----EAQKDSF-ESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQ-GSNLN 299

Query: 301 YDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKC-------VISTNISATSLT 353
            D       L  L+++P Y      ++  +F P     ++C       V++T+     + 
Sbjct: 300 PD-------LGELVVVPLY----PKEKCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIW 348

Query: 354 IDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDF 413
            + +R+V+D G  ++  +NPR+  + L + PIS+S+A  R    G +SSGK F +Y+++F
Sbjct: 349 SNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEF 408

Query: 414 WNQCMPDHVIPEIKRTSLTSVVLTLKCLAI 443
            ++ M      E++  +LTS+VL +K + I
Sbjct: 409 ASKDMTPLKPAEMQEANLTSMVLFMKRIDI 438


>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo
           sapiens]
          Length = 1270

 Score =  185 bits (469), Expect = 8e-47
 Identities = 136/448 (30%), Positives = 220/448 (49%), Gaps = 70/448 (15%)

Query: 54  PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM-----IGVTQPRK 108
           P++K   +I++A+  NS +I+ G TG GKTTQ+P+++ +  F Q+       I VTQPR+
Sbjct: 389 PVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILD-DFIQNDRAAECNIVVTQPRR 447

Query: 109 VAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETA-IKYMTDGCLLKHILGDPNLTKF 167
           ++A+SVA+RVA E     G   GY VRF+    +  A I + T G LL+ +  +  +   
Sbjct: 448 ISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKL--EAGIRGI 505

Query: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227
           S +I+DE HER + TD L  +L+ + Q         +++V+MSAT++ +    +F NCPI
Sbjct: 506 SHVIVDEIHERDINTDFLLVVLRDVVQAYP-----EVRIVLMSATIDTSMFCEYFFNCPI 560

Query: 228 FDIPGRLYPVREKF---------------------------------CNLI-----GPRD 249
            ++ GR YPV+E F                                 CNLI     GP  
Sbjct: 561 IEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGPET 620

Query: 250 R-------ENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYD 302
           R       E     + I  +   I    + G +LVFL G         L++ M + ++ +
Sbjct: 621 RLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPG-------WNLIYTMQKHLEMN 673

Query: 303 YDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVD 362
                       ILP +  +  ++QR++F P P G+ K ++STNI+ TS+TI+ + YV+D
Sbjct: 674 PHFGS---HRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVID 730

Query: 363 GGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHV 422
               K         +     V  SK+   QR GRAGR   G CF + S+  + + +  H+
Sbjct: 731 SCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFER-LETHM 789

Query: 423 IPEIKRTSLTSVVLTLKCLAIHDVIRYV 450
            PE+ RT L  + L++K L +  + +++
Sbjct: 790 TPEMFRTPLHEIALSIKLLRLGGIGQFL 817


>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo
           sapiens]
          Length = 1157

 Score =  169 bits (429), Expect = 4e-42
 Identities = 110/278 (39%), Positives = 162/278 (58%), Gaps = 34/278 (12%)

Query: 20  RSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTG 79
           RS ++QEERL                        PI  + + I++AV ++  +IV G TG
Sbjct: 241 RSPEMQEERLK----------------------LPILSEEQVIMEAVAEHPIVIVCGETG 278

Query: 80  SGKTTQLPKYLYEAGFS-QHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD 138
           SGKTTQ+P++LYEAGFS +  +IGVT+PR+VAA++++QRVA+EM  +    V YQ+R++ 
Sbjct: 279 SGKTTQVPQFLYEAGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLSQ-RVVSYQIRYEG 337

Query: 139 CSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSP 198
             ++ET IK+MTDG LLK I  D  L ++ V+I+DEAHER++ TDIL GLL ++   ++ 
Sbjct: 338 NVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRA- 396

Query: 199 NRKEHLKVVVMSATMELAKLS----AFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTA 254
            R   LK+++MSAT+ +   +     F    P+  +  R +PV   F N   P +  +  
Sbjct: 397 KRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTVHF-NKRTPLEDYSGE 455

Query: 255 YIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELL 292
             + + K    IH    AG ILVFLTGQ E+   C  L
Sbjct: 456 CFRKVCK----IHRMLPAGGILVFLTGQAEVHALCRRL 489



 Score =  109 bits (272), Expect = 6e-24
 Identities = 61/159 (38%), Positives = 90/159 (56%), Gaps = 10/159 (6%)

Query: 300 DYDYDVQDTILDG---------LLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISAT 350
           D D D+ D   DG         L +LP Y  +  ++Q ++F PPP G R CV++TN++ T
Sbjct: 566 DLDLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAET 625

Query: 351 SLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYS 410
           SLTI GI+YVVD G VK+  ++   G+    V  +S++ A QR+GRAGRT  G C+R+YS
Sbjct: 626 SLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYS 685

Query: 411 KDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
              +         PEI R  +  ++L +K L +  VI +
Sbjct: 686 SAVFGD-FEQFPPPEITRRPVEDLILQMKALNVEKVINF 723


>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
           sapiens]
          Length = 717

 Score =  169 bits (427), Expect = 6e-42
 Identities = 128/401 (31%), Positives = 200/401 (49%), Gaps = 43/401 (10%)

Query: 54  PIQKQRKKIIQAVRDN--SFLIVTGNTGSGKTTQLPKYLYEAGFS---QHGMIGVTQPRK 108
           PI   R   ++ +  N    ++V+G  GSGK+TQ+P++  E   +   Q G + VTQP  
Sbjct: 46  PIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQKGQVTVTQPYP 105

Query: 109 VAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFS 168
           +AA S+A RVA+EM  TLG +VGY +  +DC+   T +++  D  LL+ +        + 
Sbjct: 106 LAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLLQEVASTRGTGAWG 165

Query: 169 VIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIF 228
           V++LDEA ER++ +D L GLL+    EK P     L+VVV++      KL AF+GN PI 
Sbjct: 166 VLVLDEAQERSVASDSLQGLLQDARLEKLPG---DLRVVVVTDPALEPKLRAFWGNPPIV 222

Query: 229 DIPGRLYPVREKFCNLIGPRDRENTAY--------IQAIVKVTMDIHLNEMAGDILVFLT 280
            IP      RE       P +R +  Y        ++A  +  +++   E+ GD+LVFL 
Sbjct: 223 HIP------RE-------PGERPSPIYWDTIPPDRVEAACQAVLELCRKELPGDVLVFLP 269

Query: 281 GQFEIEKSCELLFQMAESVDYDYDVQDTILDGL--LILPCYGSMTTDQQRRIFLPPPPGI 338
            + EI   CE L +  ES+         +L GL   +LP +       Q    +      
Sbjct: 270 SEEEISLCCESLSREVESL---------LLQGLPPRVLPLHPDCGRAVQA---VYEDMDA 317

Query: 339 RKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAG 398
           RK V++  ++  S ++  I++V+D G   +  +NPR+  +   + PISK +A  R  RA 
Sbjct: 318 RKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRAR 377

Query: 399 RTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLK 439
               G C  +Y K F     P    P +   +L+S+VL LK
Sbjct: 378 GFPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLK 418


>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
          Length = 1369

 Score =  152 bits (383), Expect = 8e-37
 Identities = 131/461 (28%), Positives = 217/461 (47%), Gaps = 82/461 (17%)

Query: 54   PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGF-----SQHGMIGVTQPRK 108
            P+ K R  I++ ++ +  ++V G TGSGK+TQ+P +L E        +    I  TQPR+
Sbjct: 573  PVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPRR 632

Query: 109  VAAISVAQRVAEEMKCTLG-----SKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPN 163
            ++A+S+A RV +E+ C  G     S  GYQ+R +  + + T + Y T G LL+ +  D  
Sbjct: 633  ISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQEDGL 692

Query: 164  LTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFG 223
            L+  S +I+DE HER++ +D L  +LK++ Q++S      L +++MSAT++  K S +F 
Sbjct: 693  LSNVSHVIVDEVHERSVQSDFLLIILKEILQKRS-----DLHLILMSATVDSEKFSTYFT 747

Query: 224  NCPIFDIPGRLYPVR----EKFCNLIGPRDRENTAYIQAIVKVTMDIHLN--EMAGDI-- 275
            +CPI  I GR YPV     E      G    +++ Y Q  ++   ++ +N    AG I  
Sbjct: 748  HCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKAGGIKK 807

Query: 276  ----LVFLTG----------QFEIEKSCELLFQMAESVDYDY----------DVQDTILD 311
                +   TG          ++       +L+     ++ D             Q   ++
Sbjct: 808  YQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIE 867

Query: 312  G--LLILP-------CYGSMTTDQQRRIFLPPPPGIR-KCVISTNISATSLTI--DGIRY 359
            G  L+ LP        Y  ++ D  RR +      I    ++ST   A + T+   G+R 
Sbjct: 868  GAVLIFLPGLAHIQQLYDLLSND--RRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRK 925

Query: 360  VV-------------------DGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRT 400
            +V                   D G  K+  ++    +  L    +SK+ ALQR GRAGR 
Sbjct: 926  IVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRV 985

Query: 401  SSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVL-TLKC 440
              G CFR+Y+++ +   M D+ +PEI R  L  + L  +KC
Sbjct: 986  RDGFCFRMYTRERFEGFM-DYSVPEILRVPLEELCLHIMKC 1025


>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
           sapiens]
          Length = 1386

 Score =  136 bits (342), Expect = 4e-32
 Identities = 73/194 (37%), Positives = 118/194 (60%), Gaps = 9/194 (4%)

Query: 52  TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFS----QHGMIGVTQPR 107
           + P  ++R+ I+  +R +  ++++G TG GKTTQ+P+++ +   +    +   I  TQPR
Sbjct: 543 SLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPR 602

Query: 108 KVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKF 167
           +++AISVA+RVA+E    +G  VGYQ+R +   S  T + Y T G LL+ + GD  L   
Sbjct: 603 RISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQGV 662

Query: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227
           S II+DE HERT  +D L  +LK +      +++  L+V++MSAT+     S +F +CP+
Sbjct: 663 SHIIVDEVHERTEESDFLLLVLKDIV-----SQRPGLQVILMSATLNAELFSDYFNSCPV 717

Query: 228 FDIPGRLYPVREKF 241
             IPGR +PV + F
Sbjct: 718 ITIPGRTFPVDQFF 731



 Score =  117 bits (293), Expect = 2e-26
 Identities = 65/193 (33%), Positives = 116/193 (60%), Gaps = 7/193 (3%)

Query: 249  DRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDT 308
            ++ N   I+A+++  +D   +   G ILVFL G  EI+    +L++  +S     + +  
Sbjct: 824  EKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIK----MLYEQLQSNSLFNNRRS- 878

Query: 309  ILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQ 368
              +  +I P + S+++++Q+ +F+ PP G+ K +ISTNI+ TS+TID + YV+D G +K+
Sbjct: 879  --NRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKE 936

Query: 369  LNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKR 428
              ++   G++ LE   +S++ ALQR GRAGR +SG CF +++   +N  +    +PEI+R
Sbjct: 937  KRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQR 996

Query: 429  TSLTSVVLTLKCL 441
              L  + L +K L
Sbjct: 997  VPLEQLCLRIKIL 1009


>gi|38505213 YTH domain containing 2 [Homo sapiens]
          Length = 1430

 Score =  132 bits (332), Expect = 6e-31
 Identities = 71/194 (36%), Positives = 126/194 (64%), Gaps = 10/194 (5%)

Query: 52  TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM---IGVTQPRK 108
           + P+ +++++I++ +++N  +++ G TGSGKTTQ+P++L +  F ++G+   I  TQPR+
Sbjct: 192 SLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCF-KNGIPCRIFCTQPRR 250

Query: 109 VAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHIL-GDPNLTKF 167
           +AAI+VA+RVA E +  +G  +GYQ+R +   S +T + + T+G LL+ ++ GD  L+  
Sbjct: 251 LAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTV 310

Query: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227
           + +I+DE HER   +D L   L+ L Q K P     LK+++ SA +++     +FG+CP+
Sbjct: 311 THVIVDEVHERDRFSDFLLTKLRDLLQ-KHPT----LKLILSSAALDVNLFIRYFGSCPV 365

Query: 228 FDIPGRLYPVREKF 241
             I GR + V+E F
Sbjct: 366 IYIQGRPFEVKEMF 379



 Score = 95.5 bits (236), Expect = 9e-20
 Identities = 61/172 (35%), Positives = 97/172 (56%), Gaps = 10/172 (5%)

Query: 272 AGDILVFLTGQFEIEKSCE-LLFQMAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRI 330
           AG +L+FL G  EI    + +LF      D  +  Q  +L        + +M T  Q+++
Sbjct: 622 AGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFML--------HSNMQTSDQKKV 673

Query: 331 FLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEA 390
              PP G+RK ++STNI+ TS+T++ + +V+D G VK+ + +    + +L++V ISK+ A
Sbjct: 674 LKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASA 733

Query: 391 LQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLA 442
           +QR GRAGR   G CFR++S+    Q M +   PE+ R  L  + L  K LA
Sbjct: 734 IQRKGRAGRCRPGICFRLFSR-LRFQNMLEFQTPELLRMPLQELCLHTKLLA 784


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 80/381 (20%), Positives = 138/381 (36%), Gaps = 63/381 (16%)

Query: 48  GTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPR 107
           G T  FPIQ    K    V +   LI    TG+GKT      L E        I  ++  
Sbjct: 156 GVTYLFPIQV---KTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQETIKKSRSP 212

Query: 108 KVAAIS----VAQRVAEEMK---------CTLGSKVGYQVRFDDCSSKETAIKYMTDGCL 154
           KV  ++    +A +VA++ K         C  G    YQ + +   +    I   T G +
Sbjct: 213 KVLVLAPTRELANQVAKDFKDITRKLSVACFYGG-TSYQSQINHIRN-GIDILVGTPGRI 270

Query: 155 LKHI-LGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATM 213
             H+  G  +L+K   ++LDE  ++ L       +   + +    + +++ + ++ SAT 
Sbjct: 271 KDHLQSGRLDLSKLRHVVLDEV-DQMLDLGFAEQVEDIIHESYKTDSEDNPQTLLFSAT- 328

Query: 214 ELAKLSAFFGNCP--IFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEM 271
                      CP  ++ +  +    R +  +L+G   ++    ++ +           +
Sbjct: 329 -----------CPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAV 377

Query: 272 AGDIL-VFLTGQFEIEKSCELLFQMAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRI 330
            GD+L V+   +      CE    + E     +  Q+          C        QR I
Sbjct: 378 IGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNA--------QCLHGDIAQSQREI 429

Query: 331 FLPP-PPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSE 389
            L     G  K +++TN++A  L I                  P + L I    P     
Sbjct: 430 TLKGFREGSFKVLVATNVAARGLDI------------------PEVDLVIQSSPPQDVES 471

Query: 390 ALQRSGRAGRTS-SGKCFRIY 409
            + RSGR GR   +G C   Y
Sbjct: 472 YIHRSGRTGRAGRTGICICFY 492


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 295   MAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTI 354
             + E  +Y+Y V      GL  LP   S     +  +FLP PP   K V S     T++TI
Sbjct: 26047 LREGCEYEYRVYAENAAGLS-LPSETSPLIRAEDPVFLPSPPSKPKIVDS---GKTTITI 26102

Query: 355   DGIRYVVDGG 364
               ++ + DGG
Sbjct: 26103 AWVKPLFDGG 26112


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 295   MAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTI 354
             + E  +Y+Y V      GL  LP   S     +  +FLP PP   K V S     T++TI
Sbjct: 19742 LREGCEYEYRVYAENAAGLS-LPSETSPLIRAEDPVFLPSPPSKPKIVDS---GKTTITI 19797

Query: 355   DGIRYVVDGG 364
               ++ + DGG
Sbjct: 19798 AWVKPLFDGG 19807


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 295   MAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTI 354
             + E  +Y+Y V      GL  LP   S     +  +FLP PP   K V S     T++TI
Sbjct: 19675 LREGCEYEYRVYAENAAGLS-LPSETSPLIRAEDPVFLPSPPSKPKIVDS---GKTTITI 19730

Query: 355   DGIRYVVDGG 364
               ++ + DGG
Sbjct: 19731 AWVKPLFDGG 19740


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 295   MAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTI 354
             + E  +Y+Y V      GL  LP   S     +  +FLP PP   K V S     T++TI
Sbjct: 19550 LREGCEYEYRVYAENAAGLS-LPSETSPLIRAEDPVFLPSPPSKPKIVDS---GKTTITI 19605

Query: 355   DGIRYVVDGG 364
               ++ + DGG
Sbjct: 19606 AWVKPLFDGG 19615


>gi|19923796 NMD3 homolog [Homo sapiens]
          Length = 503

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 10/98 (10%)

Query: 326 QQRRIFLPPPPGIRKCVISTNISATSLT-----IDGIRYVVDGGFVKQLNHNPRLGLDIL 380
           Q +R F PP   I+  + S  + A  L      +  +R +VD GFV    H+ RL + + 
Sbjct: 57  QCQRYFQPPGTWIQCALESRELLALCLKKIKAPLSKVR-LVDAGFVWTEPHSKRLKVKLT 115

Query: 381 EVVPISKSEALQR----SGRAGRTSSGKCFRIYSKDFW 414
               +     LQ+             G C R+ +KDFW
Sbjct: 116 IQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFW 153


>gi|195927059 axin 2 [Homo sapiens]
          Length = 843

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 11/120 (9%)

Query: 5   PAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQ 64
           P  AG     +EEG+RS+D+ +  L     ++R+ K        T   +P++  R     
Sbjct: 600 PGGAGALQLPREEGDRSQDVWQWMLE----SERQSKPKPHSAQSTKKAYPLESARSS--P 653

Query: 65  AVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVA-QRVAEEMK 123
             R +   +  GN+G  +TT       +       M  +T P  +A +  A +R+AE  K
Sbjct: 654 GERASRHHLWGGNSGHPRTTPRAHLFTQ----DPAMPPLTPPNTLAQLEEACRRLAEVSK 709


>gi|31543667 suppressor of var1, 3-like 1 [Homo sapiens]
          Length = 786

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 14/22 (63%), Positives = 18/22 (81%)

Query: 381 EVVPISKSEALQRSGRAGRTSS 402
           E+ PI+ S+ALQ +GRAGR SS
Sbjct: 455 ELEPITTSQALQIAGRAGRFSS 476


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,854,839
Number of Sequences: 37866
Number of extensions: 723790
Number of successful extensions: 1867
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1770
Number of HSP's gapped (non-prelim): 63
length of query: 452
length of database: 18,247,518
effective HSP length: 106
effective length of query: 346
effective length of database: 14,233,722
effective search space: 4924867812
effective search space used: 4924867812
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.