BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|110825963 poly (ADP-ribose) polymerase family, member 2 isoform 2 [Homo sapiens] (570 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|110825963 poly (ADP-ribose) polymerase family, member 2 isofo... 1159 0.0 gi|110825961 poly (ADP-ribose) polymerase family, member 2 isofo... 1150 0.0 gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo... 386 e-107 gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 265 8e-71 gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo... 265 8e-71 gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo... 103 3e-22 gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 43 9e-04 gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo ... 41 0.003 gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 40 0.008 gi|94536838 poly (ADP-ribose) polymerase family, member 6 [Homo ... 39 0.013 gi|154354979 myosin X [Homo sapiens] 38 0.022 gi|221219020 NYD-SP11 protein [Homo sapiens] 36 0.083 gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 35 0.14 gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 35 0.14 gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 35 0.14 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 35 0.19 gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 34 0.41 gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 34 0.41 gi|30794488 kinesin family member 27 [Homo sapiens] 34 0.41 gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa... 33 0.70 gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa... 33 0.70 gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 32 1.6 gi|15559211 RE1-silencing transcription factor [Homo sapiens] 32 1.6 gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 32 1.6 gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Hom... 32 1.6 gi|4505531 oxysterol binding protein [Homo sapiens] 32 1.6 gi|122937211 KIAA0368 protein [Homo sapiens] 32 1.6 gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sap... 32 2.0 gi|42476024 THUMP domain containing 1 [Homo sapiens] 32 2.0 gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 31 2.7 >gi|110825963 poly (ADP-ribose) polymerase family, member 2 isoform 2 [Homo sapiens] Length = 570 Score = 1159 bits (2998), Expect = 0.0 Identities = 570/570 (100%), Positives = 570/570 (100%) Query: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD Sbjct: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60 Query: 61 RTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYL 120 RTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYL Sbjct: 61 RTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYL 120 Query: 121 IQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREK 180 IQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREK Sbjct: 121 IQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREK 180 Query: 181 FEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEE 240 FEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEE Sbjct: 181 FEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEE 240 Query: 241 MMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDF 300 MMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDF Sbjct: 241 MMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDF 300 Query: 301 GLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLD 360 GLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLD Sbjct: 301 GLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLD 360 Query: 361 HESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMS 420 HESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMS Sbjct: 361 HESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMS 420 Query: 421 NWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALG 480 NWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALG Sbjct: 421 NWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALG 480 Query: 481 QCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYT 540 QCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYT Sbjct: 481 QCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYT 540 Query: 541 LNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 570 LNYNEYIVYNPNQVRMRYLLKVQFNFLQLW Sbjct: 541 LNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 570 >gi|110825961 poly (ADP-ribose) polymerase family, member 2 isoform 1 [Homo sapiens] Length = 583 Score = 1150 bits (2974), Expect = 0.0 Identities = 570/583 (97%), Positives = 570/583 (97%), Gaps = 13/583 (2%) Query: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD Sbjct: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60 Query: 61 RTEDKQD-------------ESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN 107 RTEDKQD ESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN Sbjct: 61 RTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN 120 Query: 108 QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF 167 QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF Sbjct: 121 QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF 180 Query: 168 LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE 227 LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE Sbjct: 181 LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE 240 Query: 228 LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 287 LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME Sbjct: 241 LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 300 Query: 288 ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ 347 ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ Sbjct: 301 ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ 360 Query: 348 HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL 407 HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL Sbjct: 361 HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL 420 Query: 408 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 467 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK Sbjct: 421 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 480 Query: 468 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 527 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP Sbjct: 481 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 540 Query: 528 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 570 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW Sbjct: 541 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 583 >gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo sapiens] Length = 1014 Score = 386 bits (991), Expect = e-107 Identities = 216/516 (41%), Positives = 323/516 (62%), Gaps = 17/516 (3%) Query: 59 KDRTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKY 118 K+ +K ++ +K L LKG A VDP+ + AHV +G V+ L ++ N Y Sbjct: 512 KEEGINKSEKRMK-LTLKGGAAVDPDSGLE-HSAHVLEKGGKVFSATLGLVDIVKGTNSY 569 Query: 119 YLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDR 178 Y +QLLEDD + + ++ WGRVG + + + + A E F K + +KT N W + Sbjct: 570 YKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK 629 Query: 179 EKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAM 238 F K P K+ L++DY QDEE KK L +S+L VQ+LIK+I +V++M Sbjct: 630 N-FTKYPKKFYPLEIDYG---QDEEAVKK---LTVNPGTKSKLPKPVQDLIKMIFDVESM 682 Query: 239 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPH 298 ++ M+E + + +K PLGKL+ QI+A Y L +++ + G +++ N FYT IPH Sbjct: 683 KKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPH 742 Query: 299 DFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQ-SPEHPLDQHYRNLHCALR 357 DFG++ PPL+ + K+++L+ L DIE+A L++ S + P+D +Y L ++ Sbjct: 743 DFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIK 802 Query: 358 PLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLHNRMLLWH 415 +D +S E ++I +Y+++THA TH+ Y + ++D+F++E++GE + ++ + LHNR LLWH Sbjct: 803 VVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWH 862 Query: 416 GSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLS 475 GSR +N+ GILS GLRIAPPEAP+TGYMFGKGIYFADM SKSANYC S+ GL+LL Sbjct: 863 GSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLG 922 Query: 476 EVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILN 535 EVALG EL A+ ++ L +GKHS KGLGK P + ++L+G VPLG +G+ Sbjct: 923 EVALGNMYELKHASHISK-LPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGV-- 979 Query: 536 PDGYTLNYNEYIVYNPNQVRMRYLLKVQFNF-LQLW 570 + +L YNEYIVY+ QV ++YLLK++FNF LW Sbjct: 980 -NDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW 1014 >gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform b [Homo sapiens] Length = 533 Score = 265 bits (677), Expect = 8e-71 Identities = 186/536 (34%), Positives = 290/536 (54%), Gaps = 38/536 (7%) Query: 46 ESKKMPVAGGKANKDRTEDKQDESVKALLLKGKA-PVDPECTAKVGKAHVYCEGNDVYDV 104 E KK AG + + R+ E++KA+ + + VDP C E Y+ Sbjct: 15 EKKKGRQAGREEDPFRSTA---EALKAIPAEKRIIRVDPTCPLSSNPGTQVYED---YNC 68 Query: 105 MLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQ 164 LNQTN++ NNNK+Y+IQLL+D + R F+ W WGRVG++GQ S + L AK+ F+ Sbjct: 69 TLNQTNIENNNNKFYIIQLLQD-SNRFFTCWNHWGRVGEVGQ-SKINHFTRLEDAKKDFE 126 Query: 165 KKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQ---- 220 KKF +KTKNNW +R+ F PGKY ++++ +DE + + + P++ ++ Sbjct: 127 KKFREKTKNNWAERDHFVSHPGKYTLIEV----QAEDEAQEAVVKVDRGPVRTVTKRVQP 182 Query: 221 --LDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRA 278 LD Q+LI I + + + M M + KK PLGKL+ QI G+++L+ +E+ ++ Sbjct: 183 CSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKG 242 Query: 279 -GQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEI--AIKLVK 335 G++L E + FYT IPH+FG PP I + + L K +L L DIE+ A++ V Sbjct: 243 PTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVS 302 Query: 336 TELQSPE---HPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 392 + ++ E HPLD+ Y+ L C L+ LD + E+KVI YL+ T + + TL ++ Sbjct: 303 EQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGS---NHRCPTLQHIW 359 Query: 393 EVEKDGEKEAFR--EDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYF 450 +V ++GE++ F+ L NR LLWHG+ M+ IL+ GLRI P +G GKGIYF Sbjct: 360 KVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPH----SGGRVGKGIYF 415 Query: 451 ADMSSKSANYCFASR--LKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHS--TKGLG 506 A +SKSA Y + + G + L EVALG+ + + NP + G S +G Sbjct: 416 ASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHT 475 Query: 507 KMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKV 562 + P+ + L+G V + T + +EY++Y +Q R+RYLL+V Sbjct: 476 EPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEV 531 >gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform a [Homo sapiens] Length = 540 Score = 265 bits (677), Expect = 8e-71 Identities = 186/536 (34%), Positives = 290/536 (54%), Gaps = 38/536 (7%) Query: 46 ESKKMPVAGGKANKDRTEDKQDESVKALLLKGKA-PVDPECTAKVGKAHVYCEGNDVYDV 104 E KK AG + + R+ E++KA+ + + VDP C E Y+ Sbjct: 22 EKKKGRQAGREEDPFRSTA---EALKAIPAEKRIIRVDPTCPLSSNPGTQVYED---YNC 75 Query: 105 MLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQ 164 LNQTN++ NNNK+Y+IQLL+D + R F+ W WGRVG++GQ S + L AK+ F+ Sbjct: 76 TLNQTNIENNNNKFYIIQLLQD-SNRFFTCWNHWGRVGEVGQ-SKINHFTRLEDAKKDFE 133 Query: 165 KKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQ---- 220 KKF +KTKNNW +R+ F PGKY ++++ +DE + + + P++ ++ Sbjct: 134 KKFREKTKNNWAERDHFVSHPGKYTLIEV----QAEDEAQEAVVKVDRGPVRTVTKRVQP 189 Query: 221 --LDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRA 278 LD Q+LI I + + + M M + KK PLGKL+ QI G+++L+ +E+ ++ Sbjct: 190 CSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKG 249 Query: 279 -GQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEI--AIKLVK 335 G++L E + FYT IPH+FG PP I + + L K +L L DIE+ A++ V Sbjct: 250 PTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVS 309 Query: 336 TELQSPE---HPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 392 + ++ E HPLD+ Y+ L C L+ LD + E+KVI YL+ T + + TL ++ Sbjct: 310 EQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGS---NHRCPTLQHIW 366 Query: 393 EVEKDGEKEAFR--EDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYF 450 +V ++GE++ F+ L NR LLWHG+ M+ IL+ GLRI P +G GKGIYF Sbjct: 367 KVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPH----SGGRVGKGIYF 422 Query: 451 ADMSSKSANYCFASR--LKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHS--TKGLG 506 A +SKSA Y + + G + L EVALG+ + + NP + G S +G Sbjct: 423 ASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHT 482 Query: 507 KMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKV 562 + P+ + L+G V + T + +EY++Y +Q R+RYLL+V Sbjct: 483 EPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEV 538 >gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo sapiens] Length = 1724 Score = 103 bits (258), Expect = 3e-22 Identities = 90/351 (25%), Positives = 148/351 (42%), Gaps = 52/351 (14%) Query: 219 SQLDLRVQELIKLICN--VQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCI 276 S L V +L+++I + +E M+++ P+ ++++ + L ++ + Sbjct: 257 STLSQEVSDLVEMIWAEALGHLEHMLLK--------PVNRISLNDVSKAEGILLLVKAAL 308 Query: 277 RAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKT 336 + G+ L + EFY IPH T P L++K L + + D+ + + +T Sbjct: 309 KNGETAEQLQKMMTEFYRLIPHK---GTMPKEVNLGLLAKKADLCQLIRDM---VNVCET 362 Query: 337 ELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEK 396 L P P YR L C + ++ + EF + + + H HS + +L +F V + Sbjct: 363 NLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNH---HSKSPVDVLQIFRVGR 419 Query: 397 DGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYM------FGKGIYF 450 E F L N L HGS + N VGIL GL + P G G GIYF Sbjct: 420 VNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGL-LLPKVVEDRGVQRTDVGNLGSGIYF 478 Query: 451 ADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAP 510 +D S S Y T LLL+ +VALG+C +L E + G S G+ + A Sbjct: 479 SDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTAS 538 Query: 511 SSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLK 561 + F +E++VY NQV+M+Y++K Sbjct: 539 VTTDF--------------------------EDDEFVVYKTNQVKMKYIIK 563 >gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase [Homo sapiens] Length = 1327 Score = 42.7 bits (99), Expect = 9e-04 Identities = 47/156 (30%), Positives = 60/156 (38%), Gaps = 23/156 (14%) Query: 408 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 467 HN +L+HGS N I+ G G MFG GIYFA+ SSKS Y + Sbjct: 1177 HNERMLFHGSPFIN--AIIHKGF---DERHAYIGGMFGAGIYFAENSSKSNQYVYGIG-G 1230 Query: 468 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 527 TG + + C+ Q LGK S F T+ + P G Sbjct: 1231 GTGCPTHKDRSCYICHR------------QMLFCRVTLGK---SFLQFSTMKMAHAPPGH 1275 Query: 528 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQ 563 S G P L Y EY++Y Q YL+ Q Sbjct: 1276 HSVIG--RPSVNGLAYAEYVIYRGEQAYPEYLITYQ 1309 >gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo sapiens] Length = 854 Score = 40.8 bits (94), Expect = 0.003 Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 1/48 (2%) Query: 414 WHGSRMSNWVGILSHGLRIAP-PEAPITGYMFGKGIYFADMSSKSANY 460 +HGS + NW IL +GL +A + G M+G GIY + MSS S Y Sbjct: 696 FHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSISFGY 743 >gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 [Homo sapiens] Length = 1166 Score = 39.7 bits (91), Expect = 0.008 Identities = 55/222 (24%), Positives = 84/222 (37%), Gaps = 40/222 (18%) Query: 359 LDHESYEFKVISQYLQST----HAPTHSDYTMTLLDLFEVEKDGEKEAFREDLH------ 408 L + EF+ + + +QST H+ ++ +++K K+ + H Sbjct: 958 LSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVS 1017 Query: 409 -------NRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYC 461 N +L+HGS N I+ G G MFG GIYFA+ SSKS Y Sbjct: 1018 EENHNHANERMLFHGSPFVN--AIIHKGF---DERHAYIGGMFGAGIYFAENSSKSNQYV 1072 Query: 462 FASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGS 521 + TG + + + C+ L LGK S F + + Sbjct: 1073 YGIG-GGTGCPVHKDRSCYICHRQL------------LFCRVTLGK---SFLQFSAMKMA 1116 Query: 522 TVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQ 563 P G S TG + +G L EY++Y Q YL+ Q Sbjct: 1117 HSPPGHHSVTGRPSVNGLAL--AEYVIYRGEQAYPEYLITYQ 1156 >gi|94536838 poly (ADP-ribose) polymerase family, member 6 [Homo sapiens] Length = 630 Score = 38.9 bits (89), Expect = 0.013 Identities = 40/158 (25%), Positives = 60/158 (37%), Gaps = 25/158 (15%) Query: 309 RTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHY---RNLHCALRPLDHESYE 365 R QK L + + E + IK +L HPL Q H PL + Sbjct: 381 RLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSRLKF- 439 Query: 366 FKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLHNRMLLWHGSRMSNWV 423 H+ + LL ++ FR + L+ +HGS + NW Sbjct: 440 --------------MHTSHQFLLLS----SPPAKEARFRTAKKLYGSTFAFHGSHIENWH 481 Query: 424 GILSHGL-RIAPPEAPITGYMFGKGIYFADMSSKSANY 460 IL +GL + + + G +GKGIY + +SS S Y Sbjct: 482 SILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISFGY 519 >gi|154354979 myosin X [Homo sapiens] Length = 2058 Score = 38.1 bits (87), Expect = 0.022 Identities = 27/123 (21%), Positives = 61/123 (49%), Gaps = 14/123 (11%) Query: 169 DKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDL----- 223 +K K E+++K E+ + + + + Q EEET+K++ L++ K + + +L Sbjct: 820 EKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELE 879 Query: 224 ------RVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIR 277 +V+E+++L ++ ++ M + + + +A L KL Q + + + E+ R Sbjct: 880 KQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKL---QERRDQELRRLEEEACR 936 Query: 278 AGQ 280 A Q Sbjct: 937 AAQ 939 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 36.2 bits (82), Expect = 0.083 Identities = 51/239 (21%), Positives = 92/239 (38%), Gaps = 41/239 (17%) Query: 13 RARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDESVKA 72 R RA E KR ++ + R QE +K+ A K +D E Q E Sbjct: 1579 RKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAE---- 1634 Query: 73 LLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNF 132 GK E A+ G+ L Q E AQ+ Sbjct: 1635 ----GKFAQKEETLAQRGEK---------------------------LSQEAEKLAQKRK 1663 Query: 133 SVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF--LDKTKNN--WEDREKFEKVPG-K 187 + +W +V + + L G L + K I +K L + + N W+++E +++ + Sbjct: 1664 KLAKKWEKVARE-EEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELE 1722 Query: 188 YDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMK 246 +DM ++ + ++EE K E K + E L + ++L + + EE++++ K Sbjct: 1723 WDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEK 1781 Score = 29.6 bits (65), Expect = 7.8 Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 160 KEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESL-------K 212 KE +KK K K E +EK E K +++ + + DEEE ++ SL K Sbjct: 2282 KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341 Query: 213 SPLKPESQLDLRVQ 226 LK E Q L+ Q Sbjct: 2342 EILKKEKQFKLQEQ 2355 >gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] Length = 1780 Score = 35.4 bits (80), Expect = 0.14 Identities = 32/138 (23%), Positives = 59/138 (42%), Gaps = 23/138 (16%) Query: 176 EDREKFEKVPGKYDMLQMDYATNTQDEEETKKEE---------SLKSPLKPESQLDLRVQ 226 EDRE+F K + ++L D ++ ++E LK+ + Q D ++ Sbjct: 1449 EDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIE 1508 Query: 227 ELIKLICNVQAMEEMMMEMK-YNTKKAPLGKLTVAQIKAGYQ-SLKKIEDCIRAGQHGRA 284 +L ++I +E +M++K A KL + ++ S KIED G Sbjct: 1509 QLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIED-------GSV 1561 Query: 285 LMEAC-----NEFYTRIP 297 ++++C N+ TR P Sbjct: 1562 VLDSCEVSTENDQSTRFP 1579 >gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] Length = 1226 Score = 35.4 bits (80), Expect = 0.14 Identities = 34/144 (23%), Positives = 70/144 (48%), Gaps = 21/144 (14%) Query: 168 LDKTKNNWEDREKFEKVPGKYDM-------LQMDYATNTQDEEETKKEESLKSPL----- 215 L ++++ ED E+ E G DM ++D+ TN +++ +K+E++ S L Sbjct: 621 LQASESSAEDSEQ-EDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKV 679 Query: 216 -------KPESQLDLRVQELIKLIC-NVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQ 267 KP S+ R+++ I+++ + E+ + + + + KK K + QIK G + Sbjct: 680 HADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKDVKKDTTDKSSKPQIKRGKR 739 Query: 268 SLKKIEDCIRAGQHGRALMEACNE 291 E+C++ G G+ +A N+ Sbjct: 740 RYCNTEECLKTGSPGKKEEKAKNK 763 >gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] Length = 1312 Score = 35.4 bits (80), Expect = 0.14 Identities = 34/144 (23%), Positives = 70/144 (48%), Gaps = 21/144 (14%) Query: 168 LDKTKNNWEDREKFEKVPGKYDM-------LQMDYATNTQDEEETKKEESLKSPL----- 215 L ++++ ED E+ E G DM ++D+ TN +++ +K+E++ S L Sbjct: 707 LQASESSAEDSEQ-EDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKV 765 Query: 216 -------KPESQLDLRVQELIKLIC-NVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQ 267 KP S+ R+++ I+++ + E+ + + + + KK K + QIK G + Sbjct: 766 HADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKDVKKDTTDKSSKPQIKRGKR 825 Query: 268 SLKKIEDCIRAGQHGRALMEACNE 291 E+C++ G G+ +A N+ Sbjct: 826 RYCNTEECLKTGSPGKKEEKAKNK 849 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 35.0 bits (79), Expect = 0.19 Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 5/64 (7%) Query: 5 RRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTED 64 RRRS R R+ + S+ SSP K+++ + + K GG+++K++ +D Sbjct: 82 RRRSRSRDRRRSRSRSR-----GRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKD 136 Query: 65 KQDE 68 K D+ Sbjct: 137 KDDK 140 >gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens] Length = 1758 Score = 33.9 bits (76), Expect = 0.41 Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 6/85 (7%) Query: 178 REKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQA 237 +E E P K + ++ DY+ + + E+ T KEE K P + LD + ++ + Sbjct: 1063 KEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK------RKRK 1116 Query: 238 MEEMMMEMKYNTKKAPLGKLTVAQI 262 EE ++ + + + KL V +I Sbjct: 1117 TEEKGVDKDFESSSMKISKLEVTEI 1141 >gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens] Length = 1792 Score = 33.9 bits (76), Expect = 0.41 Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 6/85 (7%) Query: 178 REKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQA 237 +E E P K + ++ DY+ + + E+ T KEE K P + LD + ++ + Sbjct: 1097 KEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK------RKRK 1150 Query: 238 MEEMMMEMKYNTKKAPLGKLTVAQI 262 EE ++ + + + KL V +I Sbjct: 1151 TEEKGVDKDFESSSMKISKLEVTEI 1175 >gi|30794488 kinesin family member 27 [Homo sapiens] Length = 1401 Score = 33.9 bits (76), Expect = 0.41 Identities = 34/167 (20%), Positives = 73/167 (43%), Gaps = 23/167 (13%) Query: 190 MLQMDYATNTQDEEETKKEES---------LKSP-----------LKPESQLDLRVQELI 229 +L ++ N+ DEE +E+S ++ P + E+Q E + Sbjct: 637 VLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDL 696 Query: 230 KLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKK-IEDCIRAGQHGRALMEA 288 K+ C ++ E + ++K + + K + ++ + + I++ I+ G +++ + Sbjct: 697 KIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQ 756 Query: 289 CNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVK 335 + T++ HD LI TQK+L E + L D+ + +KL K Sbjct: 757 YSLKVTKLEHDAEQAKVELIETQKQLQELEN--KDLSDVAMKVKLQK 801 >gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sapiens] Length = 1690 Score = 33.1 bits (74), Expect = 0.70 Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 17/132 (12%) Query: 217 PESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLG-----KLTVAQIKAGYQSLKK 271 PE+ L ++++ +K ++ ++++ K +++P KLTV ++KA Q L Sbjct: 776 PENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFS 835 Query: 272 IEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGD---IE 328 + I + + L++ EF+ R TP S K+Q+L +G +E Sbjct: 836 LPCVISQARQVKNLLDDVEEFHERAQEAMMDETPD--------SSKLQMLIDMGSSLYVE 887 Query: 329 I-AIKLVKTELQ 339 + + +K ELQ Sbjct: 888 LPELPRLKQELQ 899 >gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sapiens] Length = 1641 Score = 33.1 bits (74), Expect = 0.70 Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 17/132 (12%) Query: 217 PESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLG-----KLTVAQIKAGYQSLKK 271 PE+ L ++++ +K ++ ++++ K +++P KLTV ++KA Q L Sbjct: 776 PENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFS 835 Query: 272 IEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGD---IE 328 + I + + L++ EF+ R TP S K+Q+L +G +E Sbjct: 836 LPCVISQARQVKNLLDDVEEFHERAQEAMMDETPD--------SSKLQMLIDMGSSLYVE 887 Query: 329 I-AIKLVKTELQ 339 + + +K ELQ Sbjct: 888 LPELPRLKQELQ 899 >gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b [Homo sapiens] Length = 1814 Score = 32.0 bits (71), Expect = 1.6 Identities = 29/126 (23%), Positives = 58/126 (46%), Gaps = 11/126 (8%) Query: 169 DKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQEL 228 DK K N + RE + + LQ +YA+ ++ E +KE S K + Q+L Sbjct: 1472 DKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGSEK---------ERHNQQL 1522 Query: 229 IKLI-CNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHG-RALM 286 I+ + C+ Q + + E+K + + ++ ++ +K+++ R + G + M Sbjct: 1523 IQEVRCSGQELSRVQEEVKLRQQLLSQNDKLLQSLRVELKAYEKLDEEHRRLRDGDKYPM 1582 Query: 287 EACNEF 292 E+ N F Sbjct: 1583 ESDNSF 1588 >gi|15559211 RE1-silencing transcription factor [Homo sapiens] Length = 1097 Score = 32.0 bits (71), Expect = 1.6 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 8/68 (11%) Query: 19 ESKRVNNGNTAPEDSSPA---KKTRRCQRQESKKMPVAGGKANKDRTEDKQDESVKALLL 75 ESK NN P+ S KK C ++ +KK + K++K ++ Q E V+ Sbjct: 548 ESKSKNNSQEVPKGDSKVEENKKQNTCMKKSTKKKTLK-NKSSKKSSKPPQKEPVE---- 602 Query: 76 KGKAPVDP 83 KG A +DP Sbjct: 603 KGSAQMDP 610 >gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] Length = 819 Score = 32.0 bits (71), Expect = 1.6 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 5/65 (7%) Query: 2 AARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQE-----SKKMPVAGGK 56 +A +S GGG + L E+KR +G P +P ++ ++ + SKK G K Sbjct: 374 SAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPK 433 Query: 57 ANKDR 61 A K R Sbjct: 434 AAKSR 438 >gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Homo sapiens] Length = 338 Score = 32.0 bits (71), Expect = 1.6 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 15/129 (11%) Query: 344 PLDQHYRNLHCA----LRPLDHESYEFKVISQYLQSTHAPTHSDYTMTL--LDLFEV--- 394 P+ H+ N++ L PL ++++E+ ++ T + LDL+E Sbjct: 124 PMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCR 183 Query: 395 EKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGL--RIAPPEAPITGYMFGKGIYFAD 452 +K K+ N +L+HG+ I H RI I G +FGKG YFA Sbjct: 184 KKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRING----IHGAVFGKGTYFAR 239 Query: 453 MSSKSANYC 461 ++ S+ +C Sbjct: 240 DAAYSSRFC 248 >gi|4505531 oxysterol binding protein [Homo sapiens] Length = 807 Score = 32.0 bits (71), Expect = 1.6 Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 9/122 (7%) Query: 142 GKMGQHSLVACSGNLNKAKEIFQKKFLDKTK-----NNWEDREKFEKVPGKYDMLQMDYA 196 G +G CSG + + E + +F D + N + + G + +D Sbjct: 334 GNVGSGKDQCCSGKGDMSDEDDENEFFDAPEIITMPENLGHKRTGSNISGASSDISLDEQ 393 Query: 197 TNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGK 256 Q EETKKE+ + P KP L+L I C + + ++ M + +N + L + Sbjct: 394 YKHQ-LEETKKEKRTRIPYKPNYSLNL---WSIMKNCIGKELSKIPMPVNFNEPLSMLQR 449 Query: 257 LT 258 LT Sbjct: 450 LT 451 >gi|122937211 KIAA0368 protein [Homo sapiens] Length = 2017 Score = 32.0 bits (71), Expect = 1.6 Identities = 57/214 (26%), Positives = 84/214 (39%), Gaps = 48/214 (22%) Query: 146 QHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDR-EKFEKVPG---KYDMLQMDYATNTQD 201 Q L CS K K + D K EDR ++F + K + L+ T++ Sbjct: 1790 QAVLKECSKENVKYKIVAISCAADILKATKEDRFQEFSNIVIPLIKKNSLESSGVRTTKN 1849 Query: 202 EEETKKEESLKS--------------PLKPESQLDLRVQELIKLICNVQAMEEMMMEMKY 247 EEE +KE+ L+ P E+Q R QEL KL+C +K Sbjct: 1850 EEENEKEKELQLEYLLGAFESLGKAWPRNAETQRCYR-QELCKLMCE---------RLKL 1899 Query: 248 NTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHG--RALMEACNEFYTRIPHDFGLRTP 305 +T K LG L + A +Q L +E+ +H AL E E I + +T Sbjct: 1900 STWKVQLGVL--QSMNAFFQGLMLLEE-----EHADPEALAEILLETCKSITYSLENKTY 1952 Query: 306 PLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQ 339 +RT EAL IE+ +K ++ Q Sbjct: 1953 SSVRT-----------EALSVIELLLKKLEESKQ 1975 >gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sapiens] Length = 657 Score = 31.6 bits (70), Expect = 2.0 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%) Query: 404 REDLHNRMLLWHGSRMSNWVGILSHGL--RIAPPEAPITGYMFGKGIYFADMSSKSANYC 461 R+ + N L+HG+ GI H R+ A MFG+G YFA +S S N+ Sbjct: 521 RDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHAT----MFGQGSYFAKKASYSHNFS 576 Query: 462 FASRLKNTGLLLLSEVALGQ 481 S K + L++V G+ Sbjct: 577 KKSS-KGVHFMFLAKVLTGR 595 >gi|42476024 THUMP domain containing 1 [Homo sapiens] Length = 353 Score = 31.6 bits (70), Expect = 2.0 Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 14/133 (10%) Query: 165 KKFLDKTKNNWED-REKFEKVPGKYDMLQMDYATNTQD----EEETKKEESLKSPLKPES 219 K FL+ K E E + K P K Q+ Y + EE ++ + L E+ Sbjct: 170 KAFLEDMKKYAETFLEPWFKAPNK-GTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSEN 228 Query: 220 QLDLR------VQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQI--KAGYQSLKK 271 ++DL V E+IK +C + +++ M+ KYN ++ +Q+ K G K Sbjct: 229 KVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAK 288 Query: 272 IEDCIRAGQHGRA 284 +E ++ Q+ A Sbjct: 289 LESADKSDQNNTA 301 >gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a [Homo sapiens] Length = 1893 Score = 31.2 bits (69), Expect = 2.7 Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 16/124 (12%) Query: 169 DKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQEL 228 DK K N + RE + + LQ +YA+ ++ E +KE S K + Q+L Sbjct: 1472 DKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGSEK---------ERHNQQL 1522 Query: 229 IKLI-CNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 287 I+ + C+ Q + + E+K + + ++ ++ +K+++ +H R L E Sbjct: 1523 IQEVRCSGQELSRVQEEVKLRQQLLSQNDKLLQSLRVELKAYEKLDE-----EH-RRLRE 1576 Query: 288 ACNE 291 A E Sbjct: 1577 ASGE 1580 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,894,142 Number of Sequences: 37866 Number of extensions: 1001394 Number of successful extensions: 3819 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 3743 Number of HSP's gapped (non-prelim): 92 length of query: 570 length of database: 18,247,518 effective HSP length: 108 effective length of query: 462 effective length of database: 14,157,990 effective search space: 6540991380 effective search space used: 6540991380 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.