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Search of human proteins with 110825963
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110825963 poly (ADP-ribose) polymerase family, member 2
isoform 2 [Homo sapiens]
(570 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110825963 poly (ADP-ribose) polymerase family, member 2 isofo... 1159 0.0
gi|110825961 poly (ADP-ribose) polymerase family, member 2 isofo... 1150 0.0
gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo... 386 e-107
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 265 8e-71
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo... 265 8e-71
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo... 103 3e-22
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 43 9e-04
gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo ... 41 0.003
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 40 0.008
gi|94536838 poly (ADP-ribose) polymerase family, member 6 [Homo ... 39 0.013
gi|154354979 myosin X [Homo sapiens] 38 0.022
gi|221219020 NYD-SP11 protein [Homo sapiens] 36 0.083
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 35 0.14
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 35 0.14
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 35 0.14
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 35 0.19
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 34 0.41
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 34 0.41
gi|30794488 kinesin family member 27 [Homo sapiens] 34 0.41
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa... 33 0.70
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa... 33 0.70
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 32 1.6
gi|15559211 RE1-silencing transcription factor [Homo sapiens] 32 1.6
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 32 1.6
gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Hom... 32 1.6
gi|4505531 oxysterol binding protein [Homo sapiens] 32 1.6
gi|122937211 KIAA0368 protein [Homo sapiens] 32 1.6
gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sap... 32 2.0
gi|42476024 THUMP domain containing 1 [Homo sapiens] 32 2.0
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 31 2.7
>gi|110825963 poly (ADP-ribose) polymerase family, member 2 isoform
2 [Homo sapiens]
Length = 570
Score = 1159 bits (2998), Expect = 0.0
Identities = 570/570 (100%), Positives = 570/570 (100%)
Query: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60
MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD
Sbjct: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60
Query: 61 RTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYL 120
RTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYL
Sbjct: 61 RTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYL 120
Query: 121 IQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREK 180
IQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREK
Sbjct: 121 IQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREK 180
Query: 181 FEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEE 240
FEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEE
Sbjct: 181 FEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEE 240
Query: 241 MMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDF 300
MMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDF
Sbjct: 241 MMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDF 300
Query: 301 GLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLD 360
GLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLD
Sbjct: 301 GLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLD 360
Query: 361 HESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMS 420
HESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMS
Sbjct: 361 HESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMS 420
Query: 421 NWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALG 480
NWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALG
Sbjct: 421 NWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALG 480
Query: 481 QCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYT 540
QCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYT
Sbjct: 481 QCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYT 540
Query: 541 LNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 570
LNYNEYIVYNPNQVRMRYLLKVQFNFLQLW
Sbjct: 541 LNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 570
>gi|110825961 poly (ADP-ribose) polymerase family, member 2 isoform
1 [Homo sapiens]
Length = 583
Score = 1150 bits (2974), Expect = 0.0
Identities = 570/583 (97%), Positives = 570/583 (97%), Gaps = 13/583 (2%)
Query: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60
MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD
Sbjct: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60
Query: 61 RTEDKQD-------------ESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN 107
RTEDKQD ESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN
Sbjct: 61 RTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN 120
Query: 108 QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF 167
QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF
Sbjct: 121 QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF 180
Query: 168 LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE 227
LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE
Sbjct: 181 LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE 240
Query: 228 LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 287
LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME
Sbjct: 241 LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 300
Query: 288 ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ 347
ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ
Sbjct: 301 ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ 360
Query: 348 HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL 407
HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL
Sbjct: 361 HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL 420
Query: 408 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 467
HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK
Sbjct: 421 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 480
Query: 468 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 527
NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP
Sbjct: 481 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 540
Query: 528 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 570
ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW
Sbjct: 541 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 583
>gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo
sapiens]
Length = 1014
Score = 386 bits (991), Expect = e-107
Identities = 216/516 (41%), Positives = 323/516 (62%), Gaps = 17/516 (3%)
Query: 59 KDRTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKY 118
K+ +K ++ +K L LKG A VDP+ + AHV +G V+ L ++ N Y
Sbjct: 512 KEEGINKSEKRMK-LTLKGGAAVDPDSGLE-HSAHVLEKGGKVFSATLGLVDIVKGTNSY 569
Query: 119 YLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDR 178
Y +QLLEDD + + ++ WGRVG + + + + A E F K + +KT N W +
Sbjct: 570 YKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK 629
Query: 179 EKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAM 238
F K P K+ L++DY QDEE KK L +S+L VQ+LIK+I +V++M
Sbjct: 630 N-FTKYPKKFYPLEIDYG---QDEEAVKK---LTVNPGTKSKLPKPVQDLIKMIFDVESM 682
Query: 239 EEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPH 298
++ M+E + + +K PLGKL+ QI+A Y L +++ + G +++ N FYT IPH
Sbjct: 683 KKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPH 742
Query: 299 DFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQ-SPEHPLDQHYRNLHCALR 357
DFG++ PPL+ + K+++L+ L DIE+A L++ S + P+D +Y L ++
Sbjct: 743 DFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIK 802
Query: 358 PLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLHNRMLLWH 415
+D +S E ++I +Y+++THA TH+ Y + ++D+F++E++GE + ++ + LHNR LLWH
Sbjct: 803 VVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWH 862
Query: 416 GSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLS 475
GSR +N+ GILS GLRIAPPEAP+TGYMFGKGIYFADM SKSANYC S+ GL+LL
Sbjct: 863 GSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLG 922
Query: 476 EVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILN 535
EVALG EL A+ ++ L +GKHS KGLGK P + ++L+G VPLG +G+
Sbjct: 923 EVALGNMYELKHASHISK-LPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGV-- 979
Query: 536 PDGYTLNYNEYIVYNPNQVRMRYLLKVQFNF-LQLW 570
+ +L YNEYIVY+ QV ++YLLK++FNF LW
Sbjct: 980 -NDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW 1014
>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform
b [Homo sapiens]
Length = 533
Score = 265 bits (677), Expect = 8e-71
Identities = 186/536 (34%), Positives = 290/536 (54%), Gaps = 38/536 (7%)
Query: 46 ESKKMPVAGGKANKDRTEDKQDESVKALLLKGKA-PVDPECTAKVGKAHVYCEGNDVYDV 104
E KK AG + + R+ E++KA+ + + VDP C E Y+
Sbjct: 15 EKKKGRQAGREEDPFRSTA---EALKAIPAEKRIIRVDPTCPLSSNPGTQVYED---YNC 68
Query: 105 MLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQ 164
LNQTN++ NNNK+Y+IQLL+D + R F+ W WGRVG++GQ S + L AK+ F+
Sbjct: 69 TLNQTNIENNNNKFYIIQLLQD-SNRFFTCWNHWGRVGEVGQ-SKINHFTRLEDAKKDFE 126
Query: 165 KKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQ---- 220
KKF +KTKNNW +R+ F PGKY ++++ +DE + + + P++ ++
Sbjct: 127 KKFREKTKNNWAERDHFVSHPGKYTLIEV----QAEDEAQEAVVKVDRGPVRTVTKRVQP 182
Query: 221 --LDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRA 278
LD Q+LI I + + + M M + KK PLGKL+ QI G+++L+ +E+ ++
Sbjct: 183 CSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKG 242
Query: 279 -GQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEI--AIKLVK 335
G++L E + FYT IPH+FG PP I + + L K +L L DIE+ A++ V
Sbjct: 243 PTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVS 302
Query: 336 TELQSPE---HPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 392
+ ++ E HPLD+ Y+ L C L+ LD + E+KVI YL+ T + + TL ++
Sbjct: 303 EQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGS---NHRCPTLQHIW 359
Query: 393 EVEKDGEKEAFR--EDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYF 450
+V ++GE++ F+ L NR LLWHG+ M+ IL+ GLRI P +G GKGIYF
Sbjct: 360 KVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPH----SGGRVGKGIYF 415
Query: 451 ADMSSKSANYCFASR--LKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHS--TKGLG 506
A +SKSA Y + + G + L EVALG+ + + NP + G S +G
Sbjct: 416 ASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHT 475
Query: 507 KMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKV 562
+ P+ + L+G V + T + +EY++Y +Q R+RYLL+V
Sbjct: 476 EPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEV 531
>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform
a [Homo sapiens]
Length = 540
Score = 265 bits (677), Expect = 8e-71
Identities = 186/536 (34%), Positives = 290/536 (54%), Gaps = 38/536 (7%)
Query: 46 ESKKMPVAGGKANKDRTEDKQDESVKALLLKGKA-PVDPECTAKVGKAHVYCEGNDVYDV 104
E KK AG + + R+ E++KA+ + + VDP C E Y+
Sbjct: 22 EKKKGRQAGREEDPFRSTA---EALKAIPAEKRIIRVDPTCPLSSNPGTQVYED---YNC 75
Query: 105 MLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQ 164
LNQTN++ NNNK+Y+IQLL+D + R F+ W WGRVG++GQ S + L AK+ F+
Sbjct: 76 TLNQTNIENNNNKFYIIQLLQD-SNRFFTCWNHWGRVGEVGQ-SKINHFTRLEDAKKDFE 133
Query: 165 KKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQ---- 220
KKF +KTKNNW +R+ F PGKY ++++ +DE + + + P++ ++
Sbjct: 134 KKFREKTKNNWAERDHFVSHPGKYTLIEV----QAEDEAQEAVVKVDRGPVRTVTKRVQP 189
Query: 221 --LDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRA 278
LD Q+LI I + + + M M + KK PLGKL+ QI G+++L+ +E+ ++
Sbjct: 190 CSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKG 249
Query: 279 -GQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEI--AIKLVK 335
G++L E + FYT IPH+FG PP I + + L K +L L DIE+ A++ V
Sbjct: 250 PTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVS 309
Query: 336 TELQSPE---HPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLF 392
+ ++ E HPLD+ Y+ L C L+ LD + E+KVI YL+ T + + TL ++
Sbjct: 310 EQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGS---NHRCPTLQHIW 366
Query: 393 EVEKDGEKEAFR--EDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYF 450
+V ++GE++ F+ L NR LLWHG+ M+ IL+ GLRI P +G GKGIYF
Sbjct: 367 KVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPH----SGGRVGKGIYF 422
Query: 451 ADMSSKSANYCFASR--LKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHS--TKGLG 506
A +SKSA Y + + G + L EVALG+ + + NP + G S +G
Sbjct: 423 ASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHT 482
Query: 507 KMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKV 562
+ P+ + L+G V + T + +EY++Y +Q R+RYLL+V
Sbjct: 483 EPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEV 538
>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
sapiens]
Length = 1724
Score = 103 bits (258), Expect = 3e-22
Identities = 90/351 (25%), Positives = 148/351 (42%), Gaps = 52/351 (14%)
Query: 219 SQLDLRVQELIKLICN--VQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCI 276
S L V +L+++I + +E M+++ P+ ++++ + L ++ +
Sbjct: 257 STLSQEVSDLVEMIWAEALGHLEHMLLK--------PVNRISLNDVSKAEGILLLVKAAL 308
Query: 277 RAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKT 336
+ G+ L + EFY IPH T P L++K L + + D+ + + +T
Sbjct: 309 KNGETAEQLQKMMTEFYRLIPHK---GTMPKEVNLGLLAKKADLCQLIRDM---VNVCET 362
Query: 337 ELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEK 396
L P P YR L C + ++ + EF + + + H HS + +L +F V +
Sbjct: 363 NLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNH---HSKSPVDVLQIFRVGR 419
Query: 397 DGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYM------FGKGIYF 450
E F L N L HGS + N VGIL GL + P G G GIYF
Sbjct: 420 VNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGL-LLPKVVEDRGVQRTDVGNLGSGIYF 478
Query: 451 ADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAP 510
+D S S Y T LLL+ +VALG+C +L E + G S G+ + A
Sbjct: 479 SDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTAS 538
Query: 511 SSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLK 561
+ F +E++VY NQV+M+Y++K
Sbjct: 539 VTTDF--------------------------EDDEFVVYKTNQVKMKYIIK 563
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 42.7 bits (99), Expect = 9e-04
Identities = 47/156 (30%), Positives = 60/156 (38%), Gaps = 23/156 (14%)
Query: 408 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 467
HN +L+HGS N I+ G G MFG GIYFA+ SSKS Y +
Sbjct: 1177 HNERMLFHGSPFIN--AIIHKGF---DERHAYIGGMFGAGIYFAENSSKSNQYVYGIG-G 1230
Query: 468 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 527
TG + + C+ Q LGK S F T+ + P G
Sbjct: 1231 GTGCPTHKDRSCYICHR------------QMLFCRVTLGK---SFLQFSTMKMAHAPPGH 1275
Query: 528 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQ 563
S G P L Y EY++Y Q YL+ Q
Sbjct: 1276 HSVIG--RPSVNGLAYAEYVIYRGEQAYPEYLITYQ 1309
>gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo
sapiens]
Length = 854
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 414 WHGSRMSNWVGILSHGLRIAP-PEAPITGYMFGKGIYFADMSSKSANY 460
+HGS + NW IL +GL +A + G M+G GIY + MSS S Y
Sbjct: 696 FHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSISFGY 743
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 39.7 bits (91), Expect = 0.008
Identities = 55/222 (24%), Positives = 84/222 (37%), Gaps = 40/222 (18%)
Query: 359 LDHESYEFKVISQYLQST----HAPTHSDYTMTLLDLFEVEKDGEKEAFREDLH------ 408
L + EF+ + + +QST H+ ++ +++K K+ + H
Sbjct: 958 LSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVS 1017
Query: 409 -------NRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYC 461
N +L+HGS N I+ G G MFG GIYFA+ SSKS Y
Sbjct: 1018 EENHNHANERMLFHGSPFVN--AIIHKGF---DERHAYIGGMFGAGIYFAENSSKSNQYV 1072
Query: 462 FASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGS 521
+ TG + + + C+ L LGK S F + +
Sbjct: 1073 YGIG-GGTGCPVHKDRSCYICHRQL------------LFCRVTLGK---SFLQFSAMKMA 1116
Query: 522 TVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQ 563
P G S TG + +G L EY++Y Q YL+ Q
Sbjct: 1117 HSPPGHHSVTGRPSVNGLAL--AEYVIYRGEQAYPEYLITYQ 1156
>gi|94536838 poly (ADP-ribose) polymerase family, member 6 [Homo
sapiens]
Length = 630
Score = 38.9 bits (89), Expect = 0.013
Identities = 40/158 (25%), Positives = 60/158 (37%), Gaps = 25/158 (15%)
Query: 309 RTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHY---RNLHCALRPLDHESYE 365
R QK L + + E + IK +L HPL Q H PL +
Sbjct: 381 RLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSRLKF- 439
Query: 366 FKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLHNRMLLWHGSRMSNWV 423
H+ + LL ++ FR + L+ +HGS + NW
Sbjct: 440 --------------MHTSHQFLLLS----SPPAKEARFRTAKKLYGSTFAFHGSHIENWH 481
Query: 424 GILSHGL-RIAPPEAPITGYMFGKGIYFADMSSKSANY 460
IL +GL + + + G +GKGIY + +SS S Y
Sbjct: 482 SILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISFGY 519
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 38.1 bits (87), Expect = 0.022
Identities = 27/123 (21%), Positives = 61/123 (49%), Gaps = 14/123 (11%)
Query: 169 DKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDL----- 223
+K K E+++K E+ + + + + Q EEET+K++ L++ K + + +L
Sbjct: 820 EKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELE 879
Query: 224 ------RVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIR 277
+V+E+++L ++ ++ M + + + +A L KL Q + + + E+ R
Sbjct: 880 KQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKL---QERRDQELRRLEEEACR 936
Query: 278 AGQ 280
A Q
Sbjct: 937 AAQ 939
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 36.2 bits (82), Expect = 0.083
Identities = 51/239 (21%), Positives = 92/239 (38%), Gaps = 41/239 (17%)
Query: 13 RARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDESVKA 72
R RA E KR ++ + R QE +K+ A K +D E Q E
Sbjct: 1579 RKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAE---- 1634
Query: 73 LLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNF 132
GK E A+ G+ L Q E AQ+
Sbjct: 1635 ----GKFAQKEETLAQRGEK---------------------------LSQEAEKLAQKRK 1663
Query: 133 SVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF--LDKTKNN--WEDREKFEKVPG-K 187
+ +W +V + + L G L + K I +K L + + N W+++E +++ +
Sbjct: 1664 KLAKKWEKVARE-EEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELE 1722
Query: 188 YDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMK 246
+DM ++ + ++EE K E K + E L + ++L + + EE++++ K
Sbjct: 1723 WDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEK 1781
Score = 29.6 bits (65), Expect = 7.8
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 160 KEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESL-------K 212
KE +KK K K E +EK E K +++ + + DEEE ++ SL K
Sbjct: 2282 KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341
Query: 213 SPLKPESQLDLRVQ 226
LK E Q L+ Q
Sbjct: 2342 EILKKEKQFKLQEQ 2355
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 35.4 bits (80), Expect = 0.14
Identities = 32/138 (23%), Positives = 59/138 (42%), Gaps = 23/138 (16%)
Query: 176 EDREKFEKVPGKYDMLQMDYATNTQDEEETKKEE---------SLKSPLKPESQLDLRVQ 226
EDRE+F K + ++L D ++ ++E LK+ + Q D ++
Sbjct: 1449 EDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIE 1508
Query: 227 ELIKLICNVQAMEEMMMEMK-YNTKKAPLGKLTVAQIKAGYQ-SLKKIEDCIRAGQHGRA 284
+L ++I +E +M++K A KL + ++ S KIED G
Sbjct: 1509 QLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIED-------GSV 1561
Query: 285 LMEAC-----NEFYTRIP 297
++++C N+ TR P
Sbjct: 1562 VLDSCEVSTENDQSTRFP 1579
>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
Length = 1226
Score = 35.4 bits (80), Expect = 0.14
Identities = 34/144 (23%), Positives = 70/144 (48%), Gaps = 21/144 (14%)
Query: 168 LDKTKNNWEDREKFEKVPGKYDM-------LQMDYATNTQDEEETKKEESLKSPL----- 215
L ++++ ED E+ E G DM ++D+ TN +++ +K+E++ S L
Sbjct: 621 LQASESSAEDSEQ-EDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKV 679
Query: 216 -------KPESQLDLRVQELIKLIC-NVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQ 267
KP S+ R+++ I+++ + E+ + + + + KK K + QIK G +
Sbjct: 680 HADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKDVKKDTTDKSSKPQIKRGKR 739
Query: 268 SLKKIEDCIRAGQHGRALMEACNE 291
E+C++ G G+ +A N+
Sbjct: 740 RYCNTEECLKTGSPGKKEEKAKNK 763
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 35.4 bits (80), Expect = 0.14
Identities = 34/144 (23%), Positives = 70/144 (48%), Gaps = 21/144 (14%)
Query: 168 LDKTKNNWEDREKFEKVPGKYDM-------LQMDYATNTQDEEETKKEESLKSPL----- 215
L ++++ ED E+ E G DM ++D+ TN +++ +K+E++ S L
Sbjct: 707 LQASESSAEDSEQ-EDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKV 765
Query: 216 -------KPESQLDLRVQELIKLIC-NVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQ 267
KP S+ R+++ I+++ + E+ + + + + KK K + QIK G +
Sbjct: 766 HADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKDVKKDTTDKSSKPQIKRGKR 825
Query: 268 SLKKIEDCIRAGQHGRALMEACNE 291
E+C++ G G+ +A N+
Sbjct: 826 RYCNTEECLKTGSPGKKEEKAKNK 849
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 35.0 bits (79), Expect = 0.19
Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 5 RRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTED 64
RRRS R R+ + S+ SSP K+++ + + K GG+++K++ +D
Sbjct: 82 RRRSRSRDRRRSRSRSR-----GRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKD 136
Query: 65 KQDE 68
K D+
Sbjct: 137 KDDK 140
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 33.9 bits (76), Expect = 0.41
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 178 REKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQA 237
+E E P K + ++ DY+ + + E+ T KEE K P + LD + ++ +
Sbjct: 1063 KEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK------RKRK 1116
Query: 238 MEEMMMEMKYNTKKAPLGKLTVAQI 262
EE ++ + + + KL V +I
Sbjct: 1117 TEEKGVDKDFESSSMKISKLEVTEI 1141
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 33.9 bits (76), Expect = 0.41
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 178 REKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQA 237
+E E P K + ++ DY+ + + E+ T KEE K P + LD + ++ +
Sbjct: 1097 KEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK------RKRK 1150
Query: 238 MEEMMMEMKYNTKKAPLGKLTVAQI 262
EE ++ + + + KL V +I
Sbjct: 1151 TEEKGVDKDFESSSMKISKLEVTEI 1175
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 33.9 bits (76), Expect = 0.41
Identities = 34/167 (20%), Positives = 73/167 (43%), Gaps = 23/167 (13%)
Query: 190 MLQMDYATNTQDEEETKKEES---------LKSP-----------LKPESQLDLRVQELI 229
+L ++ N+ DEE +E+S ++ P + E+Q E +
Sbjct: 637 VLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDL 696
Query: 230 KLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKK-IEDCIRAGQHGRALMEA 288
K+ C ++ E + ++K + + K + ++ + + I++ I+ G +++ +
Sbjct: 697 KIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQ 756
Query: 289 CNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVK 335
+ T++ HD LI TQK+L E + L D+ + +KL K
Sbjct: 757 YSLKVTKLEHDAEQAKVELIETQKQLQELEN--KDLSDVAMKVKLQK 801
>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
sapiens]
Length = 1690
Score = 33.1 bits (74), Expect = 0.70
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 17/132 (12%)
Query: 217 PESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLG-----KLTVAQIKAGYQSLKK 271
PE+ L ++++ +K ++ ++++ K +++P KLTV ++KA Q L
Sbjct: 776 PENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFS 835
Query: 272 IEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGD---IE 328
+ I + + L++ EF+ R TP S K+Q+L +G +E
Sbjct: 836 LPCVISQARQVKNLLDDVEEFHERAQEAMMDETPD--------SSKLQMLIDMGSSLYVE 887
Query: 329 I-AIKLVKTELQ 339
+ + +K ELQ
Sbjct: 888 LPELPRLKQELQ 899
>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
sapiens]
Length = 1641
Score = 33.1 bits (74), Expect = 0.70
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 17/132 (12%)
Query: 217 PESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLG-----KLTVAQIKAGYQSLKK 271
PE+ L ++++ +K ++ ++++ K +++P KLTV ++KA Q L
Sbjct: 776 PENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFS 835
Query: 272 IEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGD---IE 328
+ I + + L++ EF+ R TP S K+Q+L +G +E
Sbjct: 836 LPCVISQARQVKNLLDDVEEFHERAQEAMMDETPD--------SSKLQMLIDMGSSLYVE 887
Query: 329 I-AIKLVKTELQ 339
+ + +K ELQ
Sbjct: 888 LPELPRLKQELQ 899
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 32.0 bits (71), Expect = 1.6
Identities = 29/126 (23%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 169 DKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQEL 228
DK K N + RE + + LQ +YA+ ++ E +KE S K + Q+L
Sbjct: 1472 DKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGSEK---------ERHNQQL 1522
Query: 229 IKLI-CNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHG-RALM 286
I+ + C+ Q + + E+K + + ++ ++ +K+++ R + G + M
Sbjct: 1523 IQEVRCSGQELSRVQEEVKLRQQLLSQNDKLLQSLRVELKAYEKLDEEHRRLRDGDKYPM 1582
Query: 287 EACNEF 292
E+ N F
Sbjct: 1583 ESDNSF 1588
>gi|15559211 RE1-silencing transcription factor [Homo sapiens]
Length = 1097
Score = 32.0 bits (71), Expect = 1.6
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 8/68 (11%)
Query: 19 ESKRVNNGNTAPEDSSPA---KKTRRCQRQESKKMPVAGGKANKDRTEDKQDESVKALLL 75
ESK NN P+ S KK C ++ +KK + K++K ++ Q E V+
Sbjct: 548 ESKSKNNSQEVPKGDSKVEENKKQNTCMKKSTKKKTLK-NKSSKKSSKPPQKEPVE---- 602
Query: 76 KGKAPVDP 83
KG A +DP
Sbjct: 603 KGSAQMDP 610
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 32.0 bits (71), Expect = 1.6
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 2 AARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQE-----SKKMPVAGGK 56
+A +S GGG + L E+KR +G P +P ++ ++ + SKK G K
Sbjct: 374 SAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPK 433
Query: 57 ANKDR 61
A K R
Sbjct: 434 AAKSR 438
>gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Homo
sapiens]
Length = 338
Score = 32.0 bits (71), Expect = 1.6
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 15/129 (11%)
Query: 344 PLDQHYRNLHCA----LRPLDHESYEFKVISQYLQSTHAPTHSDYTMTL--LDLFEV--- 394
P+ H+ N++ L PL ++++E+ ++ T + LDL+E
Sbjct: 124 PMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCR 183
Query: 395 EKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGL--RIAPPEAPITGYMFGKGIYFAD 452
+K K+ N +L+HG+ I H RI I G +FGKG YFA
Sbjct: 184 KKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRING----IHGAVFGKGTYFAR 239
Query: 453 MSSKSANYC 461
++ S+ +C
Sbjct: 240 DAAYSSRFC 248
>gi|4505531 oxysterol binding protein [Homo sapiens]
Length = 807
Score = 32.0 bits (71), Expect = 1.6
Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 9/122 (7%)
Query: 142 GKMGQHSLVACSGNLNKAKEIFQKKFLDKTK-----NNWEDREKFEKVPGKYDMLQMDYA 196
G +G CSG + + E + +F D + N + + G + +D
Sbjct: 334 GNVGSGKDQCCSGKGDMSDEDDENEFFDAPEIITMPENLGHKRTGSNISGASSDISLDEQ 393
Query: 197 TNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGK 256
Q EETKKE+ + P KP L+L I C + + ++ M + +N + L +
Sbjct: 394 YKHQ-LEETKKEKRTRIPYKPNYSLNL---WSIMKNCIGKELSKIPMPVNFNEPLSMLQR 449
Query: 257 LT 258
LT
Sbjct: 450 LT 451
>gi|122937211 KIAA0368 protein [Homo sapiens]
Length = 2017
Score = 32.0 bits (71), Expect = 1.6
Identities = 57/214 (26%), Positives = 84/214 (39%), Gaps = 48/214 (22%)
Query: 146 QHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDR-EKFEKVPG---KYDMLQMDYATNTQD 201
Q L CS K K + D K EDR ++F + K + L+ T++
Sbjct: 1790 QAVLKECSKENVKYKIVAISCAADILKATKEDRFQEFSNIVIPLIKKNSLESSGVRTTKN 1849
Query: 202 EEETKKEESLKS--------------PLKPESQLDLRVQELIKLICNVQAMEEMMMEMKY 247
EEE +KE+ L+ P E+Q R QEL KL+C +K
Sbjct: 1850 EEENEKEKELQLEYLLGAFESLGKAWPRNAETQRCYR-QELCKLMCE---------RLKL 1899
Query: 248 NTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHG--RALMEACNEFYTRIPHDFGLRTP 305
+T K LG L + A +Q L +E+ +H AL E E I + +T
Sbjct: 1900 STWKVQLGVL--QSMNAFFQGLMLLEE-----EHADPEALAEILLETCKSITYSLENKTY 1952
Query: 306 PLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQ 339
+RT EAL IE+ +K ++ Q
Sbjct: 1953 SSVRT-----------EALSVIELLLKKLEESKQ 1975
>gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo
sapiens]
Length = 657
Score = 31.6 bits (70), Expect = 2.0
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 404 REDLHNRMLLWHGSRMSNWVGILSHGL--RIAPPEAPITGYMFGKGIYFADMSSKSANYC 461
R+ + N L+HG+ GI H R+ A MFG+G YFA +S S N+
Sbjct: 521 RDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHAT----MFGQGSYFAKKASYSHNFS 576
Query: 462 FASRLKNTGLLLLSEVALGQ 481
S K + L++V G+
Sbjct: 577 KKSS-KGVHFMFLAKVLTGR 595
>gi|42476024 THUMP domain containing 1 [Homo sapiens]
Length = 353
Score = 31.6 bits (70), Expect = 2.0
Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 14/133 (10%)
Query: 165 KKFLDKTKNNWED-REKFEKVPGKYDMLQMDYATNTQD----EEETKKEESLKSPLKPES 219
K FL+ K E E + K P K Q+ Y + EE ++ + L E+
Sbjct: 170 KAFLEDMKKYAETFLEPWFKAPNK-GTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSEN 228
Query: 220 QLDLR------VQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQI--KAGYQSLKK 271
++DL V E+IK +C + +++ M+ KYN ++ +Q+ K G K
Sbjct: 229 KVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAK 288
Query: 272 IEDCIRAGQHGRA 284
+E ++ Q+ A
Sbjct: 289 LESADKSDQNNTA 301
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 31.2 bits (69), Expect = 2.7
Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 16/124 (12%)
Query: 169 DKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQEL 228
DK K N + RE + + LQ +YA+ ++ E +KE S K + Q+L
Sbjct: 1472 DKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGSEK---------ERHNQQL 1522
Query: 229 IKLI-CNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 287
I+ + C+ Q + + E+K + + ++ ++ +K+++ +H R L E
Sbjct: 1523 IQEVRCSGQELSRVQEEVKLRQQLLSQNDKLLQSLRVELKAYEKLDE-----EH-RRLRE 1576
Query: 288 ACNE 291
A E
Sbjct: 1577 ASGE 1580
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,894,142
Number of Sequences: 37866
Number of extensions: 1001394
Number of successful extensions: 3819
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 3743
Number of HSP's gapped (non-prelim): 92
length of query: 570
length of database: 18,247,518
effective HSP length: 108
effective length of query: 462
effective length of database: 14,157,990
effective search space: 6540991380
effective search space used: 6540991380
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.