BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|169166533 PREDICTED: hypothetical protein [Homo sapiens] (261 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|169166785 PREDICTED: hypothetical protein [Homo sapiens] 509 e-145 gi|169166533 PREDICTED: hypothetical protein [Homo sapiens] 509 e-145 gi|169166999 PREDICTED: hypothetical protein [Homo sapiens] 444 e-125 gi|109255251 loricrin [Homo sapiens] 62 7e-10 gi|55956899 keratin 9 [Homo sapiens] 53 3e-07 gi|119395750 keratin 1 [Homo sapiens] 51 1e-06 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 49 4e-06 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 49 4e-06 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 49 4e-06 gi|47132620 keratin 2 [Homo sapiens] 49 6e-06 gi|239752511 PREDICTED: hypothetical protein, partial [Homo sapi... 47 1e-05 gi|239746652 PREDICTED: hypothetical protein [Homo sapiens] 47 2e-05 gi|126352608 elastin isoform e precursor [Homo sapiens] 46 4e-05 gi|126352440 elastin isoform a precursor [Homo sapiens] 46 4e-05 gi|239757639 PREDICTED: similar to collagen, type I, alpha 2 [Ho... 46 4e-05 gi|155969697 keratin 6C [Homo sapiens] 45 8e-05 gi|119703753 keratin 6B [Homo sapiens] 45 8e-05 gi|126352446 elastin isoform d precursor [Homo sapiens] 44 1e-04 gi|126352322 elastin isoform c precursor [Homo sapiens] 44 1e-04 gi|126352700 elastin isoform b precursor [Homo sapiens] 44 1e-04 gi|60593038 keratin associated protein 5-4 [Homo sapiens] 44 1e-04 gi|239747654 PREDICTED: hypothetical protein XP_002348126 [Homo ... 44 2e-04 gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol... 44 2e-04 gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo... 44 2e-04 gi|5031839 keratin 6A [Homo sapiens] 43 2e-04 gi|7710121 engrailed homeobox 2 [Homo sapiens] 42 4e-04 gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens] 42 5e-04 gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens] 42 7e-04 gi|195972866 keratin 10 [Homo sapiens] 42 7e-04 gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 42 7e-04 >gi|169166785 PREDICTED: hypothetical protein [Homo sapiens] Length = 261 Score = 509 bits (1311), Expect = e-145 Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MTPTLSGNRTCPSQETEQSVGLDQNKQAKLKTLIVTEVVVWCVGAAEVSEVSGARVVGEE 60 MTPTLSGNRTCPSQETEQSVGLDQNKQAKLKTLIVTEVVVWCVGAAEVSEVSGARVVGEE Sbjct: 1 MTPTLSGNRTCPSQETEQSVGLDQNKQAKLKTLIVTEVVVWCVGAAEVSEVSGARVVGEE 60 Query: 61 LGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGA 120 LGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGA Sbjct: 61 LGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGA 120 Query: 121 EEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVG 180 EEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVG Sbjct: 121 EEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVG 180 Query: 181 GAAVVSCGAGEFTGANVATEELVLTFSLEDMVVAFWGRKVTFGRVVILVEADGKVTDGIW 240 GAAVVSCGAGEFTGANVATEELVLTFSLEDMVVAFWGRKVTFGRVVILVEADGKVTDGIW Sbjct: 181 GAAVVSCGAGEFTGANVATEELVLTFSLEDMVVAFWGRKVTFGRVVILVEADGKVTDGIW 240 Query: 241 VVATKVGLTTLLFLSGCLGGW 261 VVATKVGLTTLLFLSGCLGGW Sbjct: 241 VVATKVGLTTLLFLSGCLGGW 261 >gi|169166533 PREDICTED: hypothetical protein [Homo sapiens] Length = 261 Score = 509 bits (1311), Expect = e-145 Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MTPTLSGNRTCPSQETEQSVGLDQNKQAKLKTLIVTEVVVWCVGAAEVSEVSGARVVGEE 60 MTPTLSGNRTCPSQETEQSVGLDQNKQAKLKTLIVTEVVVWCVGAAEVSEVSGARVVGEE Sbjct: 1 MTPTLSGNRTCPSQETEQSVGLDQNKQAKLKTLIVTEVVVWCVGAAEVSEVSGARVVGEE 60 Query: 61 LGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGA 120 LGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGA Sbjct: 61 LGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGA 120 Query: 121 EEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVG 180 EEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVG Sbjct: 121 EEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVG 180 Query: 181 GAAVVSCGAGEFTGANVATEELVLTFSLEDMVVAFWGRKVTFGRVVILVEADGKVTDGIW 240 GAAVVSCGAGEFTGANVATEELVLTFSLEDMVVAFWGRKVTFGRVVILVEADGKVTDGIW Sbjct: 181 GAAVVSCGAGEFTGANVATEELVLTFSLEDMVVAFWGRKVTFGRVVILVEADGKVTDGIW 240 Query: 241 VVATKVGLTTLLFLSGCLGGW 261 VVATKVGLTTLLFLSGCLGGW Sbjct: 241 VVATKVGLTTLLFLSGCLGGW 261 >gi|169166999 PREDICTED: hypothetical protein [Homo sapiens] Length = 263 Score = 444 bits (1141), Expect = e-125 Identities = 227/228 (99%), Positives = 228/228 (100%) Query: 34 IVTEVVVWCVGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVV 93 +VTEVVVWCVGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVV Sbjct: 36 VVTEVVVWCVGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVV 95 Query: 94 SGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVA 153 SGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVA Sbjct: 96 SGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVA 155 Query: 154 EGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMVV 213 EGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMVV Sbjct: 156 EGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMVV 215 Query: 214 AFWGRKVTFGRVVILVEADGKVTDGIWVVATKVGLTTLLFLSGCLGGW 261 AFWGRKVTFGRVVILVEADGKVTDGIWVVATKVGLTTLLFLSGCLGGW Sbjct: 216 AFWGRKVTFGRVVILVEADGKVTDGIWVVATKVGLTTLLFLSGCLGGW 263 >gi|109255251 loricrin [Homo sapiens] Length = 312 Score = 61.6 bits (148), Expect = 7e-10 Identities = 46/140 (32%), Positives = 59/140 (42%), Gaps = 18/140 (12%) Query: 71 SCGAGEDGGAGVVAEGVGGAAVVSGGA-EADDGSRVVAEGVGGAAVVS--GGAEEDGGAG 127 S G G GG G G GG+ SGG + GS + G GG+ S GG GG+G Sbjct: 68 SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127 Query: 128 VVAGGVGGAAVVSGGAEEDGGA-----CVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGA 182 + G GG++ G GG V + GG VS G GG+G + G GG Sbjct: 128 CFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGG---VSSGGSSGGGSGCFSSGGGGG 184 Query: 183 AVV-------SCGAGEFTGA 195 +V CG G G+ Sbjct: 185 SVCGYSGGGSGCGGGSSGGS 204 Score = 56.2 bits (134), Expect = 3e-08 Identities = 43/143 (30%), Positives = 53/143 (37%), Gaps = 15/143 (10%) Query: 70 VSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVV 129 V C GG G G GG GG S GG GG G Sbjct: 14 VDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGG 73 Query: 130 AGGVGGAAVVSGGA--------EEDGGACVVAEGVGGAAVVS--GGAEEDGGAGVVAEGV 179 GG+GG SGG+ GG+ + G GG+ S GG GG+G + G Sbjct: 74 GGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG 133 Query: 180 GGAA-----VVSCGAGEFTGANV 197 GG++ S G G F+G V Sbjct: 134 GGSSGGGSGCFSSGGGGFSGQAV 156 Score = 52.8 bits (125), Expect = 3e-07 Identities = 41/143 (28%), Positives = 60/143 (41%), Gaps = 34/143 (23%) Query: 70 VSCGAGEDGGAGVVAEGVGGAAVVS---------GGAEADDGSRVVAE------------ 108 VS G GG+G + G GG +V GG+ GS V+ Sbjct: 164 VSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQP 223 Query: 109 GVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEE 168 GG + SGG G +GG GG++ GG+ G C+++ GG +V GG+ Sbjct: 224 SYGGGS--SGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIIS---GGGSVCGGGSSG 278 Query: 169 DGGAGVVAEGVGGAAVVSCGAGE 191 GG GG++V G+G+ Sbjct: 279 GGG--------GGSSVGGSGSGK 293 Score = 48.1 bits (113), Expect = 8e-06 Identities = 41/143 (28%), Positives = 53/143 (37%), Gaps = 17/143 (11%) Query: 66 GAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGG 125 G+ S G G G V + GG VS G + GS + G GG +V G Sbjct: 140 GSGCFSSGGGGFSGQAVQCQSYGG---VSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGC 196 Query: 126 AGVVAGGVGGAAVVSGGAEED--------GGACVVAEGVGGAAVVS-GGAEEDGGAGVVA 176 G +GG G V S + GG G GG+ S GG G G + Sbjct: 197 GGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGS 256 Query: 177 EGVGGAAVVS-----CGAGEFTG 194 G+G ++S CG G G Sbjct: 257 SGIGSGCIISGGGSVCGGGSSGG 279 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 52.8 bits (125), Expect = 3e-07 Identities = 49/148 (33%), Positives = 59/148 (39%), Gaps = 3/148 (2%) Query: 44 GAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGS 103 G E E SGA +G LG G + S G G GG+G G G GG+ + GS Sbjct: 460 GGQEDFESSGAGKIG--LGGR-GGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGS 516 Query: 104 RVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVS 163 G G+ SGG G G +GG GG G GG+ GG S Sbjct: 517 GGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGS 576 Query: 164 GGAEEDGGAGVVAEGVGGAAVVSCGAGE 191 G GG+ G GG + S G GE Sbjct: 577 GSRGGSGGSHGGGSGFGGESGGSYGGGE 604 Score = 46.2 bits (108), Expect = 3e-05 Identities = 37/112 (33%), Positives = 46/112 (41%), Gaps = 4/112 (3%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G+G GG+G G G+ SGG + G GG G GG+G G Sbjct: 509 GSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGS 568 Query: 133 VGGAAVVSGGAEEDGGACVVAEGVGGAAVVS-GGAEEDGGAGVVAEGVGGAA 183 GG SG GG+ G GG + S GG EE G+G G GG + Sbjct: 569 GGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSG---GGYGGGS 617 Score = 45.8 bits (107), Expect = 4e-05 Identities = 43/133 (32%), Positives = 50/133 (37%), Gaps = 18/133 (13%) Query: 71 SCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGG--AGV 128 S G G GG + G GG + SRV G GG+ S G GG A Sbjct: 37 SSGGGGGGGRFSSSSGYGGGS-----------SRVCGRGGGGSFGYSYGGGSGGGFSASS 85 Query: 129 VAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCG 188 + GG GG + GGA GG + G GG GG G G G GG G Sbjct: 86 LGGGFGGGSRGFGGA--SGGGYSSSGGFGGG---FGGGSGGGFGGGYGSGFGGFGGFGGG 140 Query: 189 AGEFTGANVATEE 201 AG G + E Sbjct: 141 AGGGDGGILTANE 153 Score = 42.4 bits (98), Expect = 4e-04 Identities = 36/120 (30%), Positives = 45/120 (37%), Gaps = 7/120 (5%) Query: 76 EDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGG 135 E GAG + G G + S G + GS G G GG+ GG+G GG G Sbjct: 466 ESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG 525 Query: 136 AAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGA 195 + SGG G GG + SGG G G G G G G +G+ Sbjct: 526 SGGGSGGGYGGGSG-------GGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGS 578 Score = 39.7 bits (91), Expect = 0.003 Identities = 38/115 (33%), Positives = 49/115 (42%), Gaps = 6/115 (5%) Query: 86 GVGGAAVVSGGAEADDGSRVVAEGVGGAAV-VSGGAEEDGGAGVVAG-GVGGAAVVSGGA 143 G GG + SGG+ SR + G GG S + GG+ V G G GG+ S G Sbjct: 16 GGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGG 75 Query: 144 EEDGG--ACVVAEGVGGAAVVSGGAEEDG--GAGVVAEGVGGAAVVSCGAGEFTG 194 GG A + G GG + GGA G +G G GG + G G +G Sbjct: 76 GSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSG 130 Score = 35.4 bits (80), Expect = 0.050 Identities = 39/118 (33%), Positives = 45/118 (38%), Gaps = 14/118 (11%) Query: 44 GAAEVSEVSG-----ARVVGEELGVVIGAAVVSCGAGEDGG--AGVVAEGVGGAAVVSGG 96 G S SG +RV G G G+ S G G GG A + G GG + GG Sbjct: 43 GGGRFSSSSGYGGGSSRVCGRGGG---GSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGG 99 Query: 97 AEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAE 154 A G + G GG G GG G GG GG +GG DGG E Sbjct: 100 ASG--GGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGG--DGGILTANE 153 Score = 32.3 bits (72), Expect = 0.43 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 4/93 (4%) Query: 92 VVSGGAEADDGSRVVAEGVGGAAVVSG--GAEEDGGAGVVAGGVGGAA-VVSGGAEEDGG 148 ++ GG E + S G+GG G G GG+G GG GG+ GG+ GG Sbjct: 457 LLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGG-GGSGGGYGGGSGSRGG 515 Query: 149 ACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGG 181 + G G+ SGG G G + G GG Sbjct: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGG 548 Score = 31.6 bits (70), Expect = 0.73 Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 8/64 (12%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVS--GGAEEDGGAGVVA 130 G+G GG+G G GG + GG+ G G GG + S GG E G G Sbjct: 561 GSGSGGGSG---GGYGGGSGSRGGSGGSHGG---GSGFGGESGGSYGGGEEASGSGGGYG 614 Query: 131 GGVG 134 GG G Sbjct: 615 GGSG 618 Score = 28.5 bits (62), Expect = 6.2 Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 3/93 (3%) Query: 109 GVGGAAVVSGGAEEDGGAGVVA-GGVGGAAVVSGGAEEDGGAC-VVAEGVGGAAVVSGGA 166 G GG + SGG+ + + GG GG S + GG+ V G GG+ S G Sbjct: 16 GGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGG 75 Query: 167 EEDGGAGVVAEGVGGAAVVSCGAGEFTGANVAT 199 GG + G GG S G G +G ++ Sbjct: 76 GSGGGFSASSLG-GGFGGGSRGFGGASGGGYSS 107 >gi|119395750 keratin 1 [Homo sapiens] Length = 644 Score = 50.8 bits (120), Expect = 1e-06 Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 10/114 (8%) Query: 62 GVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAE 121 G G+ S G+G GG G + G GG++ SGG G G GG G+ Sbjct: 529 GSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGG-----GGGGHGSYGSGSS 583 Query: 122 EDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVV 175 G G GG GG+ SGG GG+ +GG SGG + GG+ V Sbjct: 584 SGGYRGGSGGGGGGS---SGGRGSGGGSS--GGSIGGRGSSSGGVKSSGGSSSV 632 Score = 47.4 bits (111), Expect = 1e-05 Identities = 45/161 (27%), Positives = 63/161 (39%), Gaps = 9/161 (5%) Query: 47 EVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVV 106 E S +SG + V +S G GG G G GG++ SGG G Sbjct: 489 EESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGG--GYGSGGSSYGSGGGSYGSGG--- 543 Query: 107 AEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGA 166 G G + SGG+ G G G GG S G+ G G GG SGG Sbjct: 544 GGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSG-GGGGGSSGGR 602 Query: 167 EEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEELVLTFS 207 GG+ + G G+ S G + +G + + + + T+S Sbjct: 603 GSGGGSSGGSIGGRGS---SSGGVKSSGGSSSVKFVSTTYS 640 Score = 41.2 bits (95), Expect = 0.001 Identities = 40/126 (31%), Positives = 49/126 (38%), Gaps = 19/126 (15%) Query: 66 GAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDG- 124 G SCG G GG+ G G ++V+ G GS+ ++ +V GG G Sbjct: 43 GGRFSSCGGG--GGSFGAGGGFGSRSLVNLG-----GSKSIS-----ISVARGGGRGSGF 90 Query: 125 GAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAV 184 G G GG GG GG GG + G GG GG GG G G GG Sbjct: 91 GGGYGGGGFGGGGFGGGGF---GGGGIGGGGFGGFGSGGGGF---GGGGFGGGGYGGGYG 144 Query: 185 VSCGAG 190 C G Sbjct: 145 PVCPPG 150 Score = 31.6 bits (70), Expect = 0.73 Identities = 31/112 (27%), Positives = 38/112 (33%), Gaps = 5/112 (4%) Query: 88 GGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG-----VGGAAVVSGG 142 G A +++ S + G GG GG GAG G +GG+ +S Sbjct: 20 GSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISIS 79 Query: 143 AEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 GG G G GG GG G G GG G G F G Sbjct: 80 VARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGG 131 Score = 28.5 bits (62), Expect = 6.2 Identities = 27/93 (29%), Positives = 32/93 (34%), Gaps = 21/93 (22%) Query: 43 VGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDG 102 +G ++ +S AR G G G G G GG G G+GG Sbjct: 70 LGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGG------------ 117 Query: 103 SRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGG 135 G GG GG GG G GG GG Sbjct: 118 ------GFGGFGSGGGGF---GGGGFGGGGYGG 141 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 48.9 bits (115), Expect = 4e-06 Identities = 35/101 (34%), Positives = 44/101 (43%), Gaps = 9/101 (8%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G G GG G G GG +GGA G+ VA AA +GG GG G G Sbjct: 252 GGGGGGGGGGSGGGGGGGGAGAGGA----GAGAVAAAAAAAAAAAGG----GGGGGYGGS 303 Query: 133 VGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAG 173 G V+S ++ GG ++ G GGAA +S A G Sbjct: 304 SAGYGVLSSPRQQ-GGGMMMGPGGGGAASLSKAAAGSAAGG 343 Score = 43.1 bits (100), Expect = 2e-04 Identities = 35/114 (30%), Positives = 43/114 (37%), Gaps = 13/114 (11%) Query: 81 GVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVS 140 G G GG GG G G GG +GGA GAG VA AA + Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGG-----GGGGGGAGAGGA----GAGAVAAAAAAAAAAA 292 Query: 141 GGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 GG GG G V+S ++ GG + G G A++ AG G Sbjct: 293 GG----GGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG 342 Score = 34.3 bits (77), Expect = 0.11 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 6/80 (7%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGG 112 GA G G V AA + A GG G G V+S + G ++ G GG Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ-QGGGMMMGPGGGG 328 Query: 113 AAVVSGGAEEDGGAGVVAGG 132 AA +S A AG AGG Sbjct: 329 AASLSKAA-----AGSAAGG 343 Score = 31.6 bits (70), Expect = 0.73 Identities = 35/126 (27%), Positives = 41/126 (32%), Gaps = 18/126 (14%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G + G G++ AA G + S EG + GAG GG Sbjct: 198 GGQQSPGMGMMHSASAAAAGAPGSMDPLQNSH---EGYPNSQCNHYPGYSRPGAGGGGGG 254 Query: 133 VGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEF 192 GG SGG GGA G GGA G V A AA G G Sbjct: 255 GGGGGGGSGGGGGGGGA-----GAGGA----------GAGAVAAAAAAAAAAAGGGGGGG 299 Query: 193 TGANVA 198 G + A Sbjct: 300 YGGSSA 305 Score = 28.9 bits (63), Expect = 4.7 Identities = 43/170 (25%), Positives = 53/170 (31%), Gaps = 33/170 (19%) Query: 47 EVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEG---VGGAAVVSGGAEADDGS 103 ++ E +G R LG + G GG V E G AA SGG Sbjct: 133 KMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPG----- 187 Query: 104 RVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAE-----EDG----------G 148 G G G ++ G G++ AA G + +G G Sbjct: 188 -----GRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG 242 Query: 149 ACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVA 198 G GG GG GG G G GGA GAG A A Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA-----GAGAVAAAAAA 287 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 48.9 bits (115), Expect = 4e-06 Identities = 35/101 (34%), Positives = 44/101 (43%), Gaps = 9/101 (8%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G G GG G G GG +GGA G+ VA AA +GG GG G G Sbjct: 252 GGGGGGGGGGSGGGGGGGGAGAGGA----GAGAVAAAAAAAAAAAGG----GGGGGYGGS 303 Query: 133 VGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAG 173 G V+S ++ GG ++ G GGAA +S A G Sbjct: 304 SAGYGVLSSPRQQ-GGGMMMGPGGGGAASLSKAAAGSAAGG 343 Score = 43.1 bits (100), Expect = 2e-04 Identities = 35/114 (30%), Positives = 43/114 (37%), Gaps = 13/114 (11%) Query: 81 GVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVS 140 G G GG GG G G GG +GGA GAG VA AA + Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGG-----GGGGGGAGAGGA----GAGAVAAAAAAAAAAA 292 Query: 141 GGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 GG GG G V+S ++ GG + G G A++ AG G Sbjct: 293 GG----GGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG 342 Score = 34.3 bits (77), Expect = 0.11 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 6/80 (7%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGG 112 GA G G V AA + A GG G G V+S + G ++ G GG Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ-QGGGMMMGPGGGG 328 Query: 113 AAVVSGGAEEDGGAGVVAGG 132 AA +S A AG AGG Sbjct: 329 AASLSKAA-----AGSAAGG 343 Score = 31.6 bits (70), Expect = 0.73 Identities = 35/126 (27%), Positives = 41/126 (32%), Gaps = 18/126 (14%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G + G G++ AA G + S EG + GAG GG Sbjct: 198 GGQQSPGMGMMHSASAAAAGAPGSMDPLQNSH---EGYPNSQCNHYPGYSRPGAGGGGGG 254 Query: 133 VGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEF 192 GG SGG GGA G GGA G V A AA G G Sbjct: 255 GGGGGGGSGGGGGGGGA-----GAGGA----------GAGAVAAAAAAAAAAAGGGGGGG 299 Query: 193 TGANVA 198 G + A Sbjct: 300 YGGSSA 305 Score = 28.9 bits (63), Expect = 4.7 Identities = 43/170 (25%), Positives = 53/170 (31%), Gaps = 33/170 (19%) Query: 47 EVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEG---VGGAAVVSGGAEADDGS 103 ++ E +G R LG + G GG V E G AA SGG Sbjct: 133 KMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPG----- 187 Query: 104 RVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAE-----EDG----------G 148 G G G ++ G G++ AA G + +G G Sbjct: 188 -----GRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG 242 Query: 149 ACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVA 198 G GG GG GG G G GGA GAG A A Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA-----GAGAVAAAAAA 287 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 48.9 bits (115), Expect = 4e-06 Identities = 35/101 (34%), Positives = 44/101 (43%), Gaps = 9/101 (8%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G G GG G G GG +GGA G+ VA AA +GG GG G G Sbjct: 252 GGGGGGGGGGSGGGGGGGGAGAGGA----GAGAVAAAAAAAAAAAGG----GGGGGYGGS 303 Query: 133 VGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAG 173 G V+S ++ GG ++ G GGAA +S A G Sbjct: 304 SAGYGVLSSPRQQ-GGGMMMGPGGGGAASLSKAAAGSAAGG 343 Score = 43.1 bits (100), Expect = 2e-04 Identities = 35/114 (30%), Positives = 43/114 (37%), Gaps = 13/114 (11%) Query: 81 GVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVS 140 G G GG GG G G GG +GGA GAG VA AA + Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGG-----GGGGGGAGAGGA----GAGAVAAAAAAAAAAA 292 Query: 141 GGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 GG GG G V+S ++ GG + G G A++ AG G Sbjct: 293 GG----GGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG 342 Score = 34.3 bits (77), Expect = 0.11 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 6/80 (7%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGG 112 GA G G V AA + A GG G G V+S + G ++ G GG Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ-QGGGMMMGPGGGG 328 Query: 113 AAVVSGGAEEDGGAGVVAGG 132 AA +S A AG AGG Sbjct: 329 AASLSKAA-----AGSAAGG 343 Score = 31.6 bits (70), Expect = 0.73 Identities = 35/126 (27%), Positives = 41/126 (32%), Gaps = 18/126 (14%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G + G G++ AA G + S EG + GAG GG Sbjct: 198 GGQQSPGMGMMHSASAAAAGAPGSMDPLQNSH---EGYPNSQCNHYPGYSRPGAGGGGGG 254 Query: 133 VGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEF 192 GG SGG GGA G GGA G V A AA G G Sbjct: 255 GGGGGGGSGGGGGGGGA-----GAGGA----------GAGAVAAAAAAAAAAAGGGGGGG 299 Query: 193 TGANVA 198 G + A Sbjct: 300 YGGSSA 305 Score = 28.9 bits (63), Expect = 4.7 Identities = 43/170 (25%), Positives = 53/170 (31%), Gaps = 33/170 (19%) Query: 47 EVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEG---VGGAAVVSGGAEADDGS 103 ++ E +G R LG + G GG V E G AA SGG Sbjct: 133 KMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPG----- 187 Query: 104 RVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAE-----EDG----------G 148 G G G ++ G G++ AA G + +G G Sbjct: 188 -----GRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG 242 Query: 149 ACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVA 198 G GG GG GG G G GGA GAG A A Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA-----GAGAVAAAAAA 287 >gi|47132620 keratin 2 [Homo sapiens] Length = 639 Score = 48.5 bits (114), Expect = 6e-06 Identities = 37/115 (32%), Positives = 48/115 (41%), Gaps = 3/115 (2%) Query: 86 GVGGAAVVSGGAEADDGSRVVAEG-VGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAE 144 G GG SGG + S + G G+ SGG G G +GG G SGG Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGS 579 Query: 145 EDGGACVVAEGVGGAAVVSGGAEEDGGA--GVVAEGVGGAAVVSCGAGEFTGANV 197 + G G GG SGG G + G G GG++ V +GE G++V Sbjct: 580 KGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSV 634 Score = 42.4 bits (98), Expect = 4e-04 Identities = 45/148 (30%), Positives = 56/148 (37%), Gaps = 27/148 (18%) Query: 70 VSCGA-GEDGGAGVVAEGVGGAAVVSGGAEADD---------------------GSRVVA 107 +SC + G GG G G+AVVSGG+ GSR + Sbjct: 5 ISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLV 64 Query: 108 EGVGGAAVVSGGAEEDGGAGVVAGGVGG-AAVVSGGAEEDGGACVVAEGVGGAAVVSGGA 166 G+GG +S GG AGG GG GG+ GG+ G GG G Sbjct: 65 -GLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRF 123 Query: 167 EEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 GG G V G+GG G G + G Sbjct: 124 GGFGGPGGVG-GLGGPG--GFGPGGYPG 148 Score = 36.6 bits (83), Expect = 0.023 Identities = 32/102 (31%), Positives = 38/102 (37%), Gaps = 5/102 (4%) Query: 73 GAGEDGGAGVVAE---GVGGAAVVSGGAEADDGSRVVAEGVGG-AAVVSGGAEEDGGAGV 128 G G GG G + G+GG +S G A G GG GG+ GG+G Sbjct: 49 GGGGFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGF 108 Query: 129 VAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDG 170 GG GG G GG V G+GG G G Sbjct: 109 SGGGFGGGGFGGGRFGGFGGPGGVG-GLGGPGGFGPGGYPGG 149 Score = 36.6 bits (83), Expect = 0.023 Identities = 35/132 (26%), Positives = 45/132 (34%), Gaps = 27/132 (20%) Query: 52 SGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVG 111 SG R G G++ G + G G G GG +SGG G G G Sbjct: 521 SGGRGSSSGGGYSSGSSSYGSGGRQSGSRG----GSGGGGSISGGGYGSGGGSGGRYGSG 576 Query: 112 GAA---------VVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVV 162 G + SGG + G G G G SGG GG++ V Sbjct: 577 GGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGG--------------GGSSSV 622 Query: 163 SGGAEEDGGAGV 174 G + E G+ V Sbjct: 623 KGSSGEAFGSSV 634 Score = 32.3 bits (72), Expect = 0.43 Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 11/78 (14%) Query: 124 GGAGVVAGGVGGAAVVSGGAEEDGG--ACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGG 181 GG G G G+AVVSGG+ +C+ G GG GG G +V G+GG Sbjct: 14 GGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGF---GSRSLV--GLGG 68 Query: 182 AAVVSC----GAGEFTGA 195 +S G G F A Sbjct: 69 TKSISISVAGGGGGFGAA 86 Score = 31.2 bits (69), Expect = 0.95 Identities = 28/91 (30%), Positives = 33/91 (36%), Gaps = 7/91 (7%) Query: 57 VGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVV 116 +G + I A G G GG G G GG + GG+ G G GG Sbjct: 66 LGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGG------GFGGGGFG 119 Query: 117 SGGAEEDGGAGVVAGGVGGAAVVSGGAEEDG 147 G GG G V GG+GG G G Sbjct: 120 GGRFGGFGGPGGV-GGLGGPGGFGPGGYPGG 149 Score = 30.4 bits (67), Expect = 1.6 Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 15/93 (16%) Query: 91 AVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGAC 150 +V S ++ S+ G GG SGG G + G GG S G Sbjct: 502 SVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSY---GSGGRQSGSRG-------- 550 Query: 151 VVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAA 183 G GG +SGG GG G GG + Sbjct: 551 ----GSGGGGSISGGGYGSGGGSGGRYGSGGGS 579 >gi|239752511 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 609 Score = 47.4 bits (111), Expect = 1e-05 Identities = 44/151 (29%), Positives = 56/151 (37%), Gaps = 13/151 (8%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVV--- 129 G ++ A VA A+ A + V A+G+ V G A ED GV Sbjct: 261 GVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEV 320 Query: 130 -AGGVGGAAVVSGGAEEDGGACVVAE----GVGGAAVVSGGAEEDGGAGVVAEGVGGAAV 184 A GV V G A ED V E GV V G ED GVVA A+ Sbjct: 321 AAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAI 380 Query: 185 VSCG-----AGEFTGANVATEELVLTFSLED 210 A E T +A E + + ++ED Sbjct: 381 AKPDAAHGIANEVTAQGIANEVAIHSIAIED 411 Score = 39.7 bits (91), Expect = 0.003 Identities = 47/175 (26%), Positives = 61/175 (34%), Gaps = 23/175 (13%) Query: 45 AAEVSEVSGARVVGEELGV--VIGAAVVSCGAGEDGGAGVVAEGVG-GAA-------VVS 94 A ++ A V E+ V V C A ED G+ E G A + + Sbjct: 106 AHNIANEDAAHGVANEVAAQGVANEDAVHCIANEDAAQGIANEDAAHGIANEDAAQDIAN 165 Query: 95 GGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVV----AGGVGGAAVVSGGAEEDGGAC 150 A D + A+G+ V G A ED G+ GV V G A ED Sbjct: 166 EDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANED---- 221 Query: 151 VVAEGVGGAAVVSGGAEEDGGAGVVAE----GVGGAAVVSCGAGEFTGANVATEE 201 +G+ V G A ED GV E G+ V A E VA E+ Sbjct: 222 -AVQGIAKEDPVQGVANEDPVQGVANEDAVQGIANEDAVHGVAKEVAAHGVANED 275 Score = 37.0 bits (84), Expect = 0.017 Identities = 39/135 (28%), Positives = 50/135 (37%), Gaps = 10/135 (7%) Query: 45 AAEVSEVSGARVVGEELGVV-IGAAVVSCG-AGEDGGAGVV----AEGVGGAAVVSGGAE 98 A +++ AR + E+ I V+ G A ED GV A+GV V G A Sbjct: 277 AHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAQGVANEDAVEGVAN 336 Query: 99 ADDGS----RVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAE 154 D V A GV V G ED GVVA A+ A V A+ Sbjct: 337 EDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVTAQ 396 Query: 155 GVGGAAVVSGGAEED 169 G+ + A ED Sbjct: 397 GIANEVAIHSIAIED 411 Score = 31.6 bits (70), Expect = 0.73 Identities = 36/145 (24%), Positives = 51/145 (35%), Gaps = 14/145 (9%) Query: 74 AGEDGGAGVVAEG----VGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVV 129 A ED + E + V G A+ D A+G+ V A ED A V+ Sbjct: 20 ANEDAVYDIATEDAIYDIANEDAVQGIAKED-----AAQGIANEEAVHDIANEDA-AHVI 73 Query: 130 AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVV----AEGVGGAAVV 185 A ++ + A D +G+ A ED GV A+GV V Sbjct: 74 ANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDAV 133 Query: 186 SCGAGEFTGANVATEELVLTFSLED 210 C A E +A E+ + ED Sbjct: 134 HCIANEDAAQGIANEDAAHGIANED 158 >gi|239746652 PREDICTED: hypothetical protein [Homo sapiens] Length = 1513 Score = 47.0 bits (110), Expect = 2e-05 Identities = 45/167 (26%), Positives = 59/167 (35%), Gaps = 12/167 (7%) Query: 56 VVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAV 115 + E+ + V + G + A VA V V + A + V A+GV Sbjct: 1213 ITNEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA 1272 Query: 116 VSGGAEEDGGAGVV----AGGVGGAAVVSGGAEEDGGACV----VAEGVGGAAVVSGGAE 167 V G A ED GV G+ + G A ED V A+GV G A Sbjct: 1273 VHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEDAAQGVANEVAAHGVAN 1332 Query: 168 EDGGAG----VVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLED 210 ED G V A+GV A E VA E+ + ED Sbjct: 1333 EDAAHGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKED 1379 Score = 44.3 bits (103), Expect = 1e-04 Identities = 37/130 (28%), Positives = 47/130 (36%), Gaps = 8/130 (6%) Query: 56 VVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAV 115 + E+ + V + G + A VA V V + A + V A+GV Sbjct: 141 ITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA 200 Query: 116 VSGGAEEDGGAGV----VAGGVGGAAVVSGGAEEDGGACV----VAEGVGGAAVVSGGAE 167 G A ED GV A G+ G A ED V A+GV V G A Sbjct: 201 AQGVANEDAVQGVANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 260 Query: 168 EDGGAGVVAE 177 ED GV E Sbjct: 261 EDAAQGVAKE 270 Score = 42.0 bits (97), Expect = 5e-04 Identities = 41/147 (27%), Positives = 53/147 (36%), Gaps = 16/147 (10%) Query: 82 VVAEGVGGA----AVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAG----VVAGGV 133 V A GV A+ A + V A+G+ V G A ED G V A G+ Sbjct: 853 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGI 912 Query: 134 GGAAVVSGGAEEDGGACVVAE----GVGGAAVVSGGAEEDGGAGV----VAEGVGGAAVV 185 V G A ED + E GV V G A ED G+ A G+ Sbjct: 913 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 972 Query: 186 SCGAGEFTGANVATEELVLTFSLEDMV 212 A E ++A E+ + ED V Sbjct: 973 QGIANEDAAQDIANEDAAQGIAKEDPV 999 Score = 41.2 bits (95), Expect = 0.001 Identities = 54/185 (29%), Positives = 62/185 (33%), Gaps = 22/185 (11%) Query: 44 GAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAG----VVAEGVGGAAVVSGGAEA 99 G A V G E GV AV A ED G V A G+ G A Sbjct: 460 GVANEDAVQGVANEVEVQGVAHEDAVQGI-ANEDAAHGIANEVAAHGIANEDAAQGIANE 518 Query: 100 DDGSRVVAEGVGGAAVVSGGAEEDGGAG----VVAGGVGGAAVVSGGAEEDGGAC----V 151 D A+G+ V G A ED G V A GV A+ D V Sbjct: 519 D-----AAQGIAHEDAVQGIANEDAVHGIAKEVAAHGVANEDAAHAIAKPDAARGIANEV 573 Query: 152 VAEGVGGAAVVSGGAEEDGGAG----VVAEGVGGAAVVSCGAGEFTGANVATEELVLTFS 207 +G+ V G A ED G V A G+ V C A E VA E + Sbjct: 574 ATQGIATQDVADGIANEDAAHGVANEVAAHGIANEVAVHCVAIEDAAQGVAKEVTAHGVA 633 Query: 208 LEDMV 212 ED V Sbjct: 634 NEDAV 638 Score = 39.7 bits (91), Expect = 0.003 Identities = 51/180 (28%), Positives = 59/180 (32%), Gaps = 18/180 (10%) Query: 44 GAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAG----VVAEGVGGAAVVSGGAEA 99 G A V G E GV AV A ED G V A G+ G A Sbjct: 1010 GVANEDAVQGVANEVEVQGVAHEDAVQGI-ANEDAAHGIANEVAAHGIANEDAAQGIANE 1068 Query: 100 DDGSRVVAEGVGGAAVVSGGAEEDGGAGVV----AGGVGGAAVVSGGAEEDGGAC----V 151 D A+G+ V G A ED GV A GV A+ D V Sbjct: 1069 D-----AAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1123 Query: 152 VAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDM 211 A+G+ V G A ED GV E A A VA E + ED+ Sbjct: 1124 AAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDV 1183 Score = 39.3 bits (90), Expect = 0.003 Identities = 48/173 (27%), Positives = 61/173 (35%), Gaps = 16/173 (9%) Query: 44 GAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGS 103 G A+ + G E GV AV A ED G+ E + + A D + Sbjct: 929 GIAKEDPIQGVANEVEVQGVAHEDAVQGI-ANEDAAHGIANEDAA-QGIANEDAAQDIAN 986 Query: 104 RVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVS 163 A+G+ V G A ED GV V G A E V +GV V Sbjct: 987 EDAAQGIAKEDPVQGVANED-----PVQGVANEDAVQGVANE-----VEVQGVAHEDAVQ 1036 Query: 164 GGAEEDGGAG----VVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMV 212 G A ED G V A G+ A E +A E+ V + ED V Sbjct: 1037 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1089 Score = 38.9 bits (89), Expect = 0.005 Identities = 47/163 (28%), Positives = 59/163 (36%), Gaps = 27/163 (16%) Query: 49 SEVSGARVVGEELGV-VIGAAVVSCGAGEDGGAG----VVAEGVGGAAVVSGGAEADDGS 103 +EV+ V E+ V V A ED G V A GV G A D Sbjct: 188 NEVAAQGVANEDAAQGVANEDAVQGVANEDAAHGIANEVAAHGVANEDAAQGVANED--- 244 Query: 104 RVVAEGVGGAAVVSGGAEEDGGAG----VVAGGVGGAAVVSGGAEEDGGACVVAEGVGGA 159 A+GV V G A ED G V A GV V G ++ VVA Sbjct: 245 --AAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNQEALHGVVANEDAAQ 302 Query: 160 AVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEEL 202 A+ A+ D G+ EGV A E +ATE++ Sbjct: 303 AI----AKPDSAHGIANEGV---------ANEVAAQGIATEDV 332 Score = 38.1 bits (87), Expect = 0.008 Identities = 46/188 (24%), Positives = 59/188 (31%), Gaps = 36/188 (19%) Query: 56 VVGEEL--GVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGA 113 VV +E GVV A D G+ EGV G A D + + G Sbjct: 285 VVNQEALHGVVANEDAAQAIAKPDSAHGIANEGVANEVAAQGIATEDVADGIAEDAAHGI 344 Query: 114 A---------------------VVSGGAEEDGGAGV----VAGGVGGAAVVSGGAEEDGG 148 V G A ED GV A G+ G ++ED Sbjct: 345 TNEEAAQAIAKQDAAHSITNEDAVQGVANEDAAHGVANEDAAQGIANEVATHGISKED-- 402 Query: 149 ACVVAEGVGGAAVVSGGAEEDGGAGVVAE----GVGGAAVVSCGAGEFTGANVATEELVL 204 +G+ G A ED G+ E G+ V A E VA E+ V Sbjct: 403 ---AVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ 459 Query: 205 TFSLEDMV 212 + ED V Sbjct: 460 GVANEDAV 467 Score = 34.7 bits (78), Expect = 0.086 Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 9/109 (8%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAG----V 128 G ++ A VA A+ A + V +G+ V G A ED G V Sbjct: 541 GIAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATQDVADGIANEDAAHGVANEV 600 Query: 129 VAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAE 177 A G+ V A ED A+GV G A ED GVV E Sbjct: 601 AAHGIANEVAVHCVAIED-----AAQGVAKEVTAHGVANEDAVQGVVNE 644 Score = 34.3 bits (77), Expect = 0.11 Identities = 39/168 (23%), Positives = 54/168 (32%), Gaps = 4/168 (2%) Query: 49 SEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAE 108 +EV+ + +++ I + G + A +A V V A V A Sbjct: 571 NEVATQGIATQDVADGIANEDAAHGVANEVAAHGIANEVAVHCVAIEDAAQGVAKEVTAH 630 Query: 109 GVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEE 168 GV V G E VVA A+ A V A + G A E Sbjct: 631 GVANEDAVQGVVNEYALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANEDAAQGIANE 690 Query: 169 DGGAG----VVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMV 212 D G V A G+ V A E +A E+ + ED V Sbjct: 691 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAV 738 >gi|126352608 elastin isoform e precursor [Homo sapiens] Length = 705 Score = 45.8 bits (107), Expect = 4e-05 Identities = 53/162 (32%), Positives = 63/162 (38%), Gaps = 26/162 (16%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGG 112 GA + G LGV +G + GAG G V GV G V G A ++ G Sbjct: 528 GAGIPG--LGVGVGVPGLGVGAGVPGLG--VGAGVPGFGAVPGALAAAKAAKY------G 577 Query: 113 AAV--VSGGAEEDGGAGVVAGGVG-----GAAVVSGGAEEDGGACVVAEGVGGAAVVSGG 165 AAV V GG GG G+ G VG AA A+ V A G+GG V G Sbjct: 578 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 637 Query: 166 AEEDGGAGVVAE---------GVGGAAVVSCGAGEFTGANVA 198 GG G + G G V GAG+F VA Sbjct: 638 VPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVA 679 Score = 44.3 bits (103), Expect = 1e-04 Identities = 52/146 (35%), Positives = 58/146 (39%), Gaps = 19/146 (13%) Query: 66 GAAVVSCGAGEDGGAGV--VAEGVGGAAVVSGGAEADDGSRVVAEGVGGAA--VVSGGAE 121 GAA V G G G GV G+GG A V A A + GAA +V GG Sbjct: 269 GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP- 327 Query: 122 EDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAE---- 177 G GVV GV GA V G G V G+ GAA V G + A A+ Sbjct: 328 -GFGPGVV--GVPGAGVPGVGVPGAGIPVVPGAGIPGAA-VPGVVSPEAAAKAAAKAAKY 383 Query: 178 ------GVGGAAVVSCGAGEFTGANV 197 GVGG GAG F G V Sbjct: 384 GARPGVGVGGIPTYGVGAGGFPGFGV 409 Score = 42.0 bits (97), Expect = 5e-04 Identities = 46/151 (30%), Positives = 55/151 (36%), Gaps = 6/151 (3%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGG-----AAVVSGGAEADDGSRVVA 107 G VVG V G V G GAG+ V G AA + A G+R Sbjct: 330 GPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARP-G 388 Query: 108 EGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAE 167 GVGG GA G GV GG+ G A V G G V G+ A + A+ Sbjct: 389 VGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAK 448 Query: 168 EDGGAGVVAEGVGGAAVVSCGAGEFTGANVA 198 V GV V+ G G G +A Sbjct: 449 AAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA 479 Score = 41.2 bits (95), Expect = 0.001 Identities = 54/156 (34%), Positives = 60/156 (38%), Gaps = 22/156 (14%) Query: 44 GAAEVSEVSGARVVGEELGVVIGA--AVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADD 101 G + V G + G LG +GA AV GA +V GV AA A+A Sbjct: 59 GGKPLKPVPGG-LAGAGLGAGLGAFPAVTFPGA-------LVPGGVADAAAAYKAAKAGA 110 Query: 102 GSRVVAEGVGGAAVVSGGAEEDGGAGVVAG---GVGGAAVVSGGAEEDGGACVVAEGVGG 158 G V GVGG V +G GAGV G GVG V GG GVG Sbjct: 111 GLGGVP-GVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR----FPGVG- 164 Query: 159 AAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 V G G A GVGGA G G F G Sbjct: 165 ---VLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGG 197 Score = 40.0 bits (92), Expect = 0.002 Identities = 38/134 (28%), Positives = 46/134 (34%), Gaps = 10/134 (7%) Query: 66 GAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGG 125 G A + AG G GV + AA A+ G+ V GVGGA V G Sbjct: 234 GVAGAAGKAGYPTGTGVGPQAAAAAAA-KAAAKFGAGAAGVLPGVGGAGV-------PGV 285 Query: 126 AGVV--AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAA 183 G + GG+ G + A A G V G G GV GV G Sbjct: 286 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVG 345 Query: 184 VVSCGAGEFTGANV 197 V G GA + Sbjct: 346 VPGAGIPVVPGAGI 359 Score = 39.3 bits (90), Expect = 0.003 Identities = 43/128 (33%), Positives = 56/128 (43%), Gaps = 8/128 (6%) Query: 66 GAAV--VSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEED 123 GAAV V G G GG G+ GV GA + A A ++ G+ GAA + G Sbjct: 577 GAAVPGVLGGLGALGGVGIPG-GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV-- 633 Query: 124 GGAGVV-AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVS-GGAEEDGGAGVVAEGVGG 181 GG GV GG+GG + GA + +GGA GG G G+ GG Sbjct: 634 GGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 693 Query: 182 AAV-VSCG 188 A + +CG Sbjct: 694 ACLGKACG 701 Score = 38.1 bits (87), Expect = 0.008 Identities = 47/141 (33%), Positives = 57/141 (40%), Gaps = 9/141 (6%) Query: 58 GEELGVVIGAAVVSCGAGEDGGAGVVAEGVG--GAAVVSGGAEADDGSRVVAEGVGGAAV 115 G LG I A + G G G + G G G A +G A G+ V + AA Sbjct: 201 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAA 260 Query: 116 VSGGAEEDGGAGVVAGGVGGAAV--VSGGAEEDGGACVVA--EGVGGAAVVSGGAEEDGG 171 + G AGV+ GVGGA V V G GG V AA + A+ Sbjct: 261 KAAAKFGAGAAGVLP-GVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 319 Query: 172 AGVVAEGVG-GAAVVSC-GAG 190 AG+V G G G VV GAG Sbjct: 320 AGLVPGGPGFGPGVVGVPGAG 340 Score = 33.1 bits (74), Expect = 0.25 Identities = 40/119 (33%), Positives = 42/119 (35%), Gaps = 8/119 (6%) Query: 43 VGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGV-GGAAVVSGGAEADD 101 +GA GA V G GAG G GV GV GA V GA Sbjct: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKP 138 Query: 102 GSRVVAEGVGGAAVVSGGAEEDG---GAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVG 157 G GVG V GG G GV+ G GA V A GGA GVG Sbjct: 139 GK---VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAG-VKPKAPGVGGAFAGIPGVG 193 Score = 30.0 bits (66), Expect = 2.1 Identities = 59/205 (28%), Positives = 73/205 (35%), Gaps = 38/205 (18%) Query: 20 VGLDQNKQAKLKTLIVTEVVVWCVGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGG 79 VG+ QA +V VG A V+ V +G+ G V G G G Sbjct: 435 VGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAP-GVGVAPG 493 Query: 80 AGVVAEGVGGAAVVSGG-------------AEADDGSRVVAEGVG-GAAVVSGGAEEDG- 124 GV A G+G V + A A G+ + GVG G + GA G Sbjct: 494 VGV-APGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGL 552 Query: 125 GAGVVAGGVG--------------GAAV--VSGGAEEDGG----ACVVAEGVGGAAVVSG 164 G G G G GAAV V GG GG VV G AA + Sbjct: 553 GVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAK 612 Query: 165 GAEEDGGAGVV-AEGVGGAAVVSCG 188 A + G+V A G+GG V G Sbjct: 613 AAAKAAQFGLVGAAGLGGLGVGGLG 637 >gi|126352440 elastin isoform a precursor [Homo sapiens] Length = 724 Score = 45.8 bits (107), Expect = 4e-05 Identities = 53/162 (32%), Positives = 63/162 (38%), Gaps = 26/162 (16%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGG 112 GA + G LGV +G + GAG G V GV G V G A ++ G Sbjct: 547 GAGIPG--LGVGVGVPGLGVGAGVPGLG--VGAGVPGFGAVPGALAAAKAAKY------G 596 Query: 113 AAV--VSGGAEEDGGAGVVAGGVG-----GAAVVSGGAEEDGGACVVAEGVGGAAVVSGG 165 AAV V GG GG G+ G VG AA A+ V A G+GG V G Sbjct: 597 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 656 Query: 166 AEEDGGAGVVAE---------GVGGAAVVSCGAGEFTGANVA 198 GG G + G G V GAG+F VA Sbjct: 657 VPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVA 698 Score = 44.3 bits (103), Expect = 1e-04 Identities = 52/146 (35%), Positives = 58/146 (39%), Gaps = 19/146 (13%) Query: 66 GAAVVSCGAGEDGGAGV--VAEGVGGAAVVSGGAEADDGSRVVAEGVGGAA--VVSGGAE 121 GAA V G G G GV G+GG A V A A + GAA +V GG Sbjct: 269 GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP- 327 Query: 122 EDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAE---- 177 G GVV GV GA V G G V G+ GAA V G + A A+ Sbjct: 328 -GFGPGVV--GVPGAGVPGVGVPGAGIPVVPGAGIPGAA-VPGVVSPEAAAKAAAKAAKY 383 Query: 178 ------GVGGAAVVSCGAGEFTGANV 197 GVGG GAG F G V Sbjct: 384 GARPGVGVGGIPTYGVGAGGFPGFGV 409 Score = 41.6 bits (96), Expect = 7e-04 Identities = 47/152 (30%), Positives = 55/152 (36%), Gaps = 7/152 (4%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGG-----AAVVSGGAEADDGSRVVA 107 G VVG V G V G GAG+ V G AA + A G+R Sbjct: 330 GPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARP-G 388 Query: 108 EGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAE 167 GVGG GA G GV GG+ G A V G G V G+ A + A+ Sbjct: 389 VGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAK 448 Query: 168 -EDGGAGVVAEGVGGAAVVSCGAGEFTGANVA 198 G G A AA + G G VA Sbjct: 449 AAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA 480 Score = 41.2 bits (95), Expect = 0.001 Identities = 54/156 (34%), Positives = 60/156 (38%), Gaps = 22/156 (14%) Query: 44 GAAEVSEVSGARVVGEELGVVIGA--AVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADD 101 G + V G + G LG +GA AV GA +V GV AA A+A Sbjct: 59 GGKPLKPVPGG-LAGAGLGAGLGAFPAVTFPGA-------LVPGGVADAAAAYKAAKAGA 110 Query: 102 GSRVVAEGVGGAAVVSGGAEEDGGAGVVAG---GVGGAAVVSGGAEEDGGACVVAEGVGG 158 G V GVGG V +G GAGV G GVG V GG GVG Sbjct: 111 GLGGVP-GVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR----FPGVG- 164 Query: 159 AAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 V G G A GVGGA G G F G Sbjct: 165 ---VLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGG 197 Score = 40.0 bits (92), Expect = 0.002 Identities = 38/134 (28%), Positives = 46/134 (34%), Gaps = 10/134 (7%) Query: 66 GAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGG 125 G A + AG G GV + AA A+ G+ V GVGGA V G Sbjct: 234 GVAGAAGKAGYPTGTGVGPQAAAAAAA-KAAAKFGAGAAGVLPGVGGAGV-------PGV 285 Query: 126 AGVV--AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAA 183 G + GG+ G + A A G V G G GV GV G Sbjct: 286 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVG 345 Query: 184 VVSCGAGEFTGANV 197 V G GA + Sbjct: 346 VPGAGIPVVPGAGI 359 Score = 39.3 bits (90), Expect = 0.003 Identities = 43/128 (33%), Positives = 56/128 (43%), Gaps = 8/128 (6%) Query: 66 GAAV--VSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEED 123 GAAV V G G GG G+ GV GA + A A ++ G+ GAA + G Sbjct: 596 GAAVPGVLGGLGALGGVGIPG-GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV-- 652 Query: 124 GGAGVV-AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVS-GGAEEDGGAGVVAEGVGG 181 GG GV GG+GG + GA + +GGA GG G G+ GG Sbjct: 653 GGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 712 Query: 182 AAV-VSCG 188 A + +CG Sbjct: 713 ACLGKACG 720 Score = 38.1 bits (87), Expect = 0.008 Identities = 47/141 (33%), Positives = 57/141 (40%), Gaps = 9/141 (6%) Query: 58 GEELGVVIGAAVVSCGAGEDGGAGVVAEGVG--GAAVVSGGAEADDGSRVVAEGVGGAAV 115 G LG I A + G G G + G G G A +G A G+ V + AA Sbjct: 201 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAA 260 Query: 116 VSGGAEEDGGAGVVAGGVGGAAV--VSGGAEEDGGACVVA--EGVGGAAVVSGGAEEDGG 171 + G AGV+ GVGGA V V G GG V AA + A+ Sbjct: 261 KAAAKFGAGAAGVLP-GVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 319 Query: 172 AGVVAEGVG-GAAVVSC-GAG 190 AG+V G G G VV GAG Sbjct: 320 AGLVPGGPGFGPGVVGVPGAG 340 Score = 36.6 bits (83), Expect = 0.023 Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 10/123 (8%) Query: 68 AVVSCGAGEDG-GAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGA 126 A GAG G G GV G+G A V G G+ V G A+ + A + G A Sbjct: 542 AAAGLGAGIPGLGVGVGVPGLGVGAGVPG---LGVGAGVPGFGAVPGALAAAKAAKYGAA 598 Query: 127 GVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVV-AEGVGGAAVV 185 V G +GG + GG GG VV G AA + A + G+V A G+GG V Sbjct: 599 --VPGVLGGLGAL-GGVGIPGG--VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVG 653 Query: 186 SCG 188 G Sbjct: 654 GLG 656 Score = 33.1 bits (74), Expect = 0.25 Identities = 40/119 (33%), Positives = 42/119 (35%), Gaps = 8/119 (6%) Query: 43 VGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGV-GGAAVVSGGAEADD 101 +GA GA V G GAG G GV GV GA V GA Sbjct: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKP 138 Query: 102 GSRVVAEGVGGAAVVSGGAEEDG---GAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVG 157 G GVG V GG G GV+ G GA V A GGA GVG Sbjct: 139 GK---VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAG-VKPKAPGVGGAFAGIPGVG 193 >gi|239757639 PREDICTED: similar to collagen, type I, alpha 2 [Homo sapiens] Length = 2378 Score = 45.8 bits (107), Expect = 4e-05 Identities = 52/181 (28%), Positives = 67/181 (37%), Gaps = 22/181 (12%) Query: 49 SEVSGARVVGEELGVVIGAAVVSCG-AGEDGGAGVV----AEGVGGAAVVSGGAEADDGS 103 +EV+ V E+ + V + G A ED GV A+GV V G A D Sbjct: 79 NEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED--- 135 Query: 104 RVVAEGVGGAAVVSGGAEEDGGAGV----VAGGVGGAAVVSGGAEEDGGACV----VAEG 155 +GV V G A ED G+ A G+ A+ED + A+G Sbjct: 136 --AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQG 193 Query: 156 VGGAAVVSGGAEEDGGAGVVAE----GVGGAAVVSCGAGEFTGANVATEELVLTFSLEDM 211 + V G A ED G+ E GV V A E VA E V + ED Sbjct: 194 ISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDA 253 Query: 212 V 212 V Sbjct: 254 V 254 Score = 45.4 bits (106), Expect = 5e-05 Identities = 44/168 (26%), Positives = 59/168 (35%), Gaps = 14/168 (8%) Query: 49 SEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAE 108 +EV+ V E+ + V + G + A VA V V + A + V + Sbjct: 2116 NEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQ 2175 Query: 109 GVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEE 168 G+ + G A ED A GV G A ED A+GV G A E Sbjct: 2176 GIAHKDAIQGIANED-----AAQGVANEVAAHGVANED-----AAQGVANEVAAQGVANE 2225 Query: 169 DGGAGVVAE----GVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMV 212 D GV E GV A E +A E+ + ED V Sbjct: 2226 DAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV 2273 Score = 43.9 bits (102), Expect = 1e-04 Identities = 42/146 (28%), Positives = 55/146 (37%), Gaps = 13/146 (8%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAG----V 128 G ++ A VA A+ A + V A+G+ V G A ED G V Sbjct: 1199 GVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEV 1258 Query: 129 VAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAE----GVGGAAV 184 A G+ V G A ED A+G+ V G A ED G+ E GV Sbjct: 1259 AAHGISKEDAVQGIANED-----AAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDP 1313 Query: 185 VSCGAGEFTGANVATEELVLTFSLED 210 + A E VA E+ V + ED Sbjct: 1314 IQGVANEVEVQGVAHEDAVQGIANED 1339 Score = 43.9 bits (102), Expect = 1e-04 Identities = 49/177 (27%), Positives = 62/177 (35%), Gaps = 15/177 (8%) Query: 44 GAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGS 103 G A + G E GV AV A ED G+ E + + A D + Sbjct: 1307 GVANEDPIQGVANEVEVQGVAHEDAVQGI-ANEDAAHGIANEDAA-QGIANEDAAQDIAN 1364 Query: 104 RVVAEGVGGAAVVSGGAEEDGGAGVV----AGGVGGAAVVSGGAEEDGGACVVAEGVGGA 159 A+G+ V G A ED G+ GV V G A E V +GV Sbjct: 1365 EDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANE-----VEVQGVAHE 1419 Query: 160 AVVSGGAEEDGGAG----VVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMV 212 V G A ED G V A G+ A E +A E+ V + ED V Sbjct: 1420 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1476 Score = 43.1 bits (100), Expect = 2e-04 Identities = 40/136 (29%), Positives = 47/136 (34%), Gaps = 8/136 (5%) Query: 85 EGVGGAAVVSGGAEADDGS----RVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVS 140 +GV V G A D V A GV V G ED GVVA A+ Sbjct: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666 Query: 141 GGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAG----VVAEGVGGAAVVSCGAGEFTGAN 196 A V A G+ G A ED G V A G+ V A E Sbjct: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 Query: 197 VATEELVLTFSLEDMV 212 +A E+ V + ED V Sbjct: 727 IAHEDAVQGIANEDAV 742 Score = 41.6 bits (96), Expect = 7e-04 Identities = 42/149 (28%), Positives = 52/149 (34%), Gaps = 13/149 (8%) Query: 76 EDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVV----AG 131 ED GV E V + A + V A+GV V G A ED GV Sbjct: 942 EDAAQGVANEDAAHG-VANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQ 1000 Query: 132 GVGGAAVVSGGAEEDGGAC----VVAEGVGGAAVVSGGAEEDGGAG----VVAEGVGGAA 183 G+ + G A ED V A G+ G A ED G V A G+ Sbjct: 1001 GIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKED 1060 Query: 184 VVSCGAGEFTGANVATEELVLTFSLEDMV 212 V A E +A E+ + ED V Sbjct: 1061 AVQGIANEDAAQGIANEDAAQGIAHEDAV 1089 Score = 41.6 bits (96), Expect = 7e-04 Identities = 41/147 (27%), Positives = 52/147 (35%), Gaps = 16/147 (10%) Query: 82 VVAEGVGGA----AVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAG----VVAGGV 133 V A GV A+ A + V A+G+ V G ED G V A G+ Sbjct: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840 Query: 134 GGAAVVSGGAEEDGGACVVAE----GVGGAAVVSGGAEEDGGAGV----VAEGVGGAAVV 185 V G A ED + E GV V G A ED G+ A G+ Sbjct: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1900 Query: 186 SCGAGEFTGANVATEELVLTFSLEDMV 212 A E ++A E+ S ED V Sbjct: 1901 QGIANEDAAQDIANEDAAQGISKEDAV 1927 Score = 40.4 bits (93), Expect = 0.002 Identities = 41/165 (24%), Positives = 59/165 (35%), Gaps = 13/165 (7%) Query: 56 VVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAV 115 + E+ + V + G + A VA V V + A + V A+GV Sbjct: 68 ITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA 127 Query: 116 VSGGAEEDGGAGV----VAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGG 171 V G A ED GV G+ G A ED A+G+ A+ED Sbjct: 128 VQGVANEDAVQGVANEDAVQGIANEDAAHGIANED-----AAQGIANEDAAQDIAKEDAA 182 Query: 172 AGV----VAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMV 212 + A+G+ V A E +A E+ V + ED V Sbjct: 183 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPV 227 Score = 40.4 bits (93), Expect = 0.002 Identities = 50/167 (29%), Positives = 59/167 (35%), Gaps = 27/167 (16%) Query: 44 GAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAG----VVAEGVGGAAVVSGGAEA 99 G A V G E G+ AV A ED G V A GV G A Sbjct: 762 GVANEDVVQGVANEVEVQGIAHEDAVQGI-ANEDAAHGIANEVAAHGVANEDAAQGVANE 820 Query: 100 DDGSRVVAEGVGGAAVVSGGAEEDGGAG----VVAGGVGGAAVVSGGAEEDGGACVVAEG 155 D A+GV V G A ED G V A GV V G E+ VVA Sbjct: 821 D-----AAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANE 875 Query: 156 VGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEEL 202 A+ A+ D G+ EGV A E +ATE++ Sbjct: 876 DAAQAI----AKPDAAHGIANEGV---------ANEVAAQGIATEDV 909 Score = 40.4 bits (93), Expect = 0.002 Identities = 53/183 (28%), Positives = 63/183 (34%), Gaps = 22/183 (12%) Query: 44 GAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAG----VVAEGVGGAAVVSGGAEA 99 G A V G E GV AV A ED G V A G+ G A Sbjct: 1118 GVANEDAVQGVANEVEVQGVAHEDAVQGI-ANEDAAHGIANEVAAHGIANEDAAQGIANE 1176 Query: 100 DDGSRVVAEGVGGAAVVSGGAEEDGGAG----VVAGGVGGAAVVSGGAEEDGGAC----V 151 D A+G+ V G A ED G V A GV A+ D V Sbjct: 1177 D-----AAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1231 Query: 152 VAEGVGGAAVVSGGAEEDGGAG----VVAEGVGGAAVVSCGAGEFTGANVATEELVLTFS 207 A+G+ V G A ED G V A G+ V A E +A E+ V + Sbjct: 1232 AAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIA 1291 Query: 208 LED 210 ED Sbjct: 1292 NED 1294 Score = 40.4 bits (93), Expect = 0.002 Identities = 50/178 (28%), Positives = 66/178 (37%), Gaps = 25/178 (14%) Query: 45 AAEVSEVSGARVVGEELGVV-IGAAVVSCG-AGEDGGAGVV----AEGVGGAAVVSGGAE 98 A +++ AR + E+ I V+ G A ED GV A G+ V G A Sbjct: 1215 AHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIAN 1274 Query: 99 ADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGG 158 D A+G+ V G A ED A G+ V G A ED +GV Sbjct: 1275 ED-----AAQGIAKEDAVQGIANED-----AAQGIAKEDPVQGVANED-----PIQGVAN 1319 Query: 159 AAVVSGGAEEDGGAGV----VAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMV 212 V G A ED G+ A G+ A E ++A E+ S ED V Sbjct: 1320 EVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1377 Score = 40.4 bits (93), Expect = 0.002 Identities = 49/177 (27%), Positives = 59/177 (33%), Gaps = 24/177 (13%) Query: 44 GAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAG----VVAEGVGGAAVVSGGAEA 99 G A V G E GV AV A ED G V A G+ G A Sbjct: 1397 GVANEDAVQGVANEVEVQGVAHEDAVQGI-ANEDAAHGIANEVAAHGIANEDAAQGIANE 1455 Query: 100 DDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACV----VAEG 155 D A+G+ V G A ED GV G A ED + A G Sbjct: 1456 D-----AAQGIAHEDAVQGIANED-----AVHGVAKEVAAHGVANEDAAHAIAKPDAARG 1505 Query: 156 VGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMV 212 + G A ED VA+G+ A E +A E V ++ED V Sbjct: 1506 IANEVATQGIATED-----VADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAV 1557 Score = 40.4 bits (93), Expect = 0.002 Identities = 49/182 (26%), Positives = 64/182 (35%), Gaps = 14/182 (7%) Query: 45 AAEVSEVSGARVVGEELGVV-IGAAVVSCG-AGEDGGAGVV----AEGVGGAAVVSGGAE 98 A +++ AR + E+ I V+ G A ED GV A+G+ V G A Sbjct: 1494 AHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAI 1553 Query: 99 ADDGSRVVAE----GVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAE 154 D VV E GV V G ED VVA A+ A V A Sbjct: 1554 EDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAH 1613 Query: 155 GVGGAAVVSGGAEEDGGAG----VVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLED 210 + G A +D G V A G+ V A E +A E+ + ED Sbjct: 1614 SIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1673 Query: 211 MV 212 V Sbjct: 1674 AV 1675 Score = 40.0 bits (92), Expect = 0.002 Identities = 39/152 (25%), Positives = 51/152 (33%), Gaps = 25/152 (16%) Query: 76 EDGGAGVV----AEGVGGAAVVSGGAEADDG----SRVVAEGVGGAAVVSGGAEEDGGAG 127 ED G+ A+G+ V G A D + V A G+ G A ED G Sbjct: 1924 EDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQG 1983 Query: 128 VV----AGGVGGAAVVSGGAEEDGGAC-------------VVAEGVGGAAVVSGGAEEDG 170 + G+ V G A ED V A+G+ V G A ED Sbjct: 1984 IAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 2043 Query: 171 GAGVVAEGVGGAAVVSCGAGEFTGANVATEEL 202 GV E A A +ATE++ Sbjct: 2044 AHGVANEDAAQAIAKPDAAHGIANEGIATEDV 2075 Score = 39.7 bits (91), Expect = 0.003 Identities = 48/172 (27%), Positives = 60/172 (34%), Gaps = 17/172 (9%) Query: 56 VVGEEL--GVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEAD--DG-SRVVAEGV 110 VV EE GVV A D G+ EGV G A D DG ++ A G+ Sbjct: 862 VVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGI 921 Query: 111 GGAAVVSGGAEEDGGAGV----VAGGVGGAAVVSGGAEEDGGAC----VVAEGVGGAAVV 162 A++D + A GV G A ED V A+GV V Sbjct: 922 TKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAV 981 Query: 163 SGGAEEDGGAGVVAE----GVGGAAVVSCGAGEFTGANVATEELVLTFSLED 210 G A ED GV E G+ + A E +A E + ED Sbjct: 982 HGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANED 1033 Score = 38.9 bits (89), Expect = 0.005 Identities = 43/147 (29%), Positives = 48/147 (32%), Gaps = 13/147 (8%) Query: 74 AGEDGGAGVV----AEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAG-- 127 A ED G+ A GV V G A D +GV V G A ED G Sbjct: 574 ATEDVADGIANEDAAHGVANEVAVHGVAIED-----AVQGVANEDAVHGVANEDAAQGIA 628 Query: 128 --VVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVV 185 V A GV V G ED VVA A+ A V A G+ Sbjct: 629 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 688 Query: 186 SCGAGEFTGANVATEELVLTFSLEDMV 212 A E +A E S ED V Sbjct: 689 QGIANEDAAQGIANEVAAHGISKEDAV 715 Score = 38.9 bits (89), Expect = 0.005 Identities = 48/179 (26%), Positives = 62/179 (34%), Gaps = 23/179 (12%) Query: 44 GAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAG----VVAEGVGGAAVVSGGAEA 99 G A V G E G+ A+ A ED G V A G+ G A Sbjct: 983 GVANEDAVQGVANEVEVQGIAHKDAIQGI-ANEDAAHGIANEVAAHGIANEDAAQGIANE 1041 Query: 100 DDGSRVVAEGVGGAAVVSGGAEEDGGAGV----VAGGVGGAAVVSGGAEEDGGACVVAEG 155 D A+G+ G ++ED G+ A G+ G A ED +G Sbjct: 1042 D-----AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED-----AVQG 1091 Query: 156 VGGAAVVSGGAEEDGGAGVVAE----GVGGAAVVSCGAGEFTGANVATEELVLTFSLED 210 + V G A+E GV E GV V A E VA E+ V + ED Sbjct: 1092 IANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1150 Score = 38.9 bits (89), Expect = 0.005 Identities = 44/171 (25%), Positives = 57/171 (33%), Gaps = 12/171 (7%) Query: 50 EVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDG----SRV 105 EV+ V E+ I + G + V +G+ V G A D + V Sbjct: 1482 EVAAHGVANEDAAHAIAKPDAARGIANE----VATQGIATEDVADGIANEDAAHGVANEV 1537 Query: 106 VAEGVGGAAVVSGGAEEDGGAGVV----AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAV 161 A+G+ V G A ED GVV A GV V G ED VVA A+ Sbjct: 1538 AAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAI 1597 Query: 162 VSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMV 212 A V A + A + +A E S ED V Sbjct: 1598 AKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAV 1648 Score = 38.5 bits (88), Expect = 0.006 Identities = 44/171 (25%), Positives = 56/171 (32%), Gaps = 21/171 (12%) Query: 50 EVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDG----SRV 105 EV+ V E+ I + G + V +G+ V G A D V Sbjct: 314 EVAAHGVANEDAAHAIAKPDAAHGIANE----VATQGIATEDVADGIANEDAAHGVAKEV 369 Query: 106 VAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGG 165 A GV V G ED GVVA A+ A A G+ G Sbjct: 370 TAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDA---------AHGIANEVAAHGI 420 Query: 166 AEEDGGAG----VVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDMV 212 A ED G V A G+ V A E +A E+ + ED V Sbjct: 421 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAV 471 Score = 38.1 bits (87), Expect = 0.008 Identities = 38/138 (27%), Positives = 47/138 (34%), Gaps = 8/138 (5%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAG----V 128 G ++ A VA A+ A + V +G+ V G A ED G V Sbjct: 1478 GVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEV 1537 Query: 129 VAGGVGGAAVVSGGAEEDGGACVV----AEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAV 184 A G+ V G A ED VV A GV V G ED VVA A+ Sbjct: 1538 AAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAI 1597 Query: 185 VSCGAGEFTGANVATEEL 202 A VA + Sbjct: 1598 AKPDAAHGIANEVAAHSI 1615 Score = 37.7 bits (86), Expect = 0.010 Identities = 38/144 (26%), Positives = 50/144 (34%), Gaps = 14/144 (9%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G ++ A VA A+ A + V A+G+ V G A ED G Sbjct: 482 GVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED-----AVHG 536 Query: 133 VGGAAVVSGGAEEDGGACV----VAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCG 188 V G A ED + A G+ G A ED VA+G+ Sbjct: 537 VANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATED-----VADGIANEDAAHGV 591 Query: 189 AGEFTGANVATEELVLTFSLEDMV 212 A E VA E+ V + ED V Sbjct: 592 ANEVAVHGVAIEDAVQGVANEDAV 615 Score = 37.4 bits (85), Expect = 0.013 Identities = 36/142 (25%), Positives = 48/142 (33%), Gaps = 4/142 (2%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAG----V 128 G ++ A VA A+ A + V +G+ V G A ED G V Sbjct: 310 GVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEV 369 Query: 129 VAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCG 188 A GV V G ED VVA A+ A V A G+ Sbjct: 370 TAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGI 429 Query: 189 AGEFTGANVATEELVLTFSLED 210 A E ++ E+ V + ED Sbjct: 430 ANEVAAHGISKEDAVQGIANED 451 Score = 36.6 bits (83), Expect = 0.023 Identities = 45/184 (24%), Positives = 59/184 (32%), Gaps = 22/184 (11%) Query: 49 SEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAE 108 +EV+ + E++ I G + A VA A+ A + V + Sbjct: 512 NEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQ 571 Query: 109 GVGGAAVVSGGAEEDGGAGV-------------VAGGVGGAAVVSGGAEEDGGAC----V 151 G+ V G A ED GV GV V G A ED V Sbjct: 572 GIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEV 631 Query: 152 VAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCG-----AGEFTGANVATEELVLTF 206 A GV V G ED GVVA A+ A E +A E+ Sbjct: 632 TAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGI 691 Query: 207 SLED 210 + ED Sbjct: 692 ANED 695 Score = 30.8 bits (68), Expect = 1.2 Identities = 34/125 (27%), Positives = 43/125 (34%), Gaps = 7/125 (5%) Query: 74 AGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGV 133 A ED GV E A + A + V A+G+ V G A ED A GV Sbjct: 1994 ANEDAVHGVANEDAAHA-IAKPDAARGIANEVAAQGIATEDVADGIANED-----AAHGV 2047 Query: 134 GGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFT 193 A+ D + EG+ V G A ED G+ E A A T Sbjct: 2048 ANEDAAQAIAKPDAAHGIANEGIATEDVADGIA-EDAVQGITNEEAAQAIAKQDAAHGIT 2106 Query: 194 GANVA 198 + A Sbjct: 2107 KEDAA 2111 Score = 29.6 bits (65), Expect = 2.8 Identities = 33/138 (23%), Positives = 44/138 (31%), Gaps = 16/138 (11%) Query: 74 AGEDGGAGVV----AEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVV 129 A ED + A G+ G A D VA+G+ G A ED + Sbjct: 2003 ANEDAAHAIAKPDAARGIANEVAAQGIATED-----VADGIANEDAAHGVANEDAAQAIA 2057 Query: 130 AGGVGGAAVVSGGAEE---DGGACVVAEGVGGAAVVSGGAEEDGGAGV----VAEGVGGA 182 G A E DG A +G+ A++D G+ A+GV Sbjct: 2058 KPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNE 2117 Query: 183 AVVSCGAGEFTGANVATE 200 A E VA E Sbjct: 2118 VAAQGVANEDAAHGVANE 2135 >gi|155969697 keratin 6C [Homo sapiens] Length = 564 Score = 44.7 bits (104), Expect = 8e-05 Identities = 47/183 (25%), Positives = 69/183 (37%), Gaps = 13/183 (7%) Query: 71 SCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVA 130 S G+G + GGA S GS+ ++ G G A+ GG G A Sbjct: 35 SISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAI-------SGGYGSRA 87 Query: 131 GGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAG 190 GG G G GGA + G+GG A ++GG GG G GG V+ Sbjct: 88 GGSYGFGGAGSGFGFGGGA-GIGFGLGGGAGLAGGF---GGPGFPVCPPGGIQEVTVNQS 143 Query: 191 EFTGANVATEELVLTFSLE--DMVVAFWGRKVTFGRVVILVEADGKVTDGIWVVATKVGL 248 T N+ + + E + + + +F V +E KV D W + + G Sbjct: 144 LLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGT 203 Query: 249 TTL 251 T+ Sbjct: 204 KTV 206 Score = 37.0 bits (84), Expect = 0.017 Identities = 31/95 (32%), Positives = 41/95 (43%), Gaps = 13/95 (13%) Query: 109 GVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVS------GGAEE---DGGACVVAEGVGGA 159 GV + S G+G + G GGA S GG++ GG+C ++ G G Sbjct: 27 GVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSR 86 Query: 160 AVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 A GG+ GGAG G GG A + G G G Sbjct: 87 A---GGSYGFGGAG-SGFGFGGGAGIGFGLGGGAG 117 Score = 33.9 bits (76), Expect = 0.15 Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 7/78 (8%) Query: 55 RVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAA 114 R+ GE +G V + V S + GGA V G+G + GG+ GS + G+GG Sbjct: 475 RLNGEGVGQVNVSVVQSTISSGYGGASGVGSGLG----LGGGSSYSYGSGL---GIGGGF 527 Query: 115 VVSGGAEEDGGAGVVAGG 132 S G GG V GG Sbjct: 528 SSSSGRAIGGGLSSVGGG 545 Score = 28.9 bits (63), Expect = 4.7 Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 85 EGVG--GAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGG 142 EGVG +VV + G A GVG + GG+ G+G+ G+GG S G Sbjct: 479 EGVGQVNVSVVQSTISSGYGG---ASGVGSGLGLGGGSSYSYGSGL---GIGGGFSSSSG 532 Query: 143 AEEDGGACVVAEG 155 GG V G Sbjct: 533 RAIGGGLSSVGGG 545 >gi|119703753 keratin 6B [Homo sapiens] Length = 564 Score = 44.7 bits (104), Expect = 8e-05 Identities = 47/183 (25%), Positives = 69/183 (37%), Gaps = 13/183 (7%) Query: 71 SCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVA 130 S G+G + GGA S GS+ ++ G G A+ GG G A Sbjct: 35 SISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAI-------SGGYGSRA 87 Query: 131 GGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAG 190 GG G G GGA + G+GG A ++GG GG G GG V+ Sbjct: 88 GGSYGFGGAGSGFGFGGGA-GIGFGLGGGAGLAGGF---GGPGFPVCPPGGIQEVTVNQS 143 Query: 191 EFTGANVATEELVLTFSLE--DMVVAFWGRKVTFGRVVILVEADGKVTDGIWVVATKVGL 248 T N+ + + E + + + +F V +E KV D W + + G Sbjct: 144 LLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGT 203 Query: 249 TTL 251 T+ Sbjct: 204 KTV 206 Score = 37.0 bits (84), Expect = 0.017 Identities = 31/95 (32%), Positives = 41/95 (43%), Gaps = 13/95 (13%) Query: 109 GVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVS------GGAEE---DGGACVVAEGVGGA 159 GV + S G+G + G GGA S GG++ GG+C ++ G G Sbjct: 27 GVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSR 86 Query: 160 AVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 A GG+ GGAG G GG A + G G G Sbjct: 87 A---GGSYGFGGAG-SGFGFGGGAGIGFGLGGGAG 117 Score = 35.0 bits (79), Expect = 0.066 Identities = 28/78 (35%), Positives = 36/78 (46%), Gaps = 7/78 (8%) Query: 55 RVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAA 114 R+ GE +G V + V S + GGA V G+G + GG+ GS + GVGG Sbjct: 475 RLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLG----LGGGSSYSYGSGL---GVGGGF 527 Query: 115 VVSGGAEEDGGAGVVAGG 132 S G GG V GG Sbjct: 528 SSSSGRATGGGLSSVGGG 545 Score = 30.0 bits (66), Expect = 2.1 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 85 EGVG--GAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGG 142 EGVG +VV + G A GVG + GG+ G+G+ GVGG S G Sbjct: 479 EGVGQVNISVVQSTVSSGYGG---ASGVGSGLGLGGGSSYSYGSGL---GVGGGFSSSSG 532 Query: 143 AEEDGGACVVAEG 155 GG V G Sbjct: 533 RATGGGLSSVGGG 545 >gi|126352446 elastin isoform d precursor [Homo sapiens] Length = 711 Score = 44.3 bits (103), Expect = 1e-04 Identities = 52/146 (35%), Positives = 58/146 (39%), Gaps = 19/146 (13%) Query: 66 GAAVVSCGAGEDGGAGV--VAEGVGGAAVVSGGAEADDGSRVVAEGVGGAA--VVSGGAE 121 GAA V G G G GV G+GG A V A A + GAA +V GG Sbjct: 274 GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP- 332 Query: 122 EDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAE---- 177 G GVV GV GA V G G V G+ GAA V G + A A+ Sbjct: 333 -GFGPGVV--GVPGAGVPGVGVPGAGIPVVPGAGIPGAA-VPGVVSPEAAAKAAAKAAKY 388 Query: 178 ------GVGGAAVVSCGAGEFTGANV 197 GVGG GAG F G V Sbjct: 389 GARPGVGVGGIPTYGVGAGGFPGFGV 414 Score = 42.4 bits (98), Expect = 4e-04 Identities = 48/131 (36%), Positives = 57/131 (43%), Gaps = 17/131 (12%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGG 112 GA + G LGV +G + GAG G V GV G V G A ++ G Sbjct: 552 GAGIPG--LGVGVGVPGLGVGAGVPGLG--VGAGVPGFGAVPGALAAAKAAKY------G 601 Query: 113 AAV--VSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDG 170 AAV V GG GG G+ GGV GA + A A G+ GAA + G G Sbjct: 602 AAVPGVLGGLGALGGVGIP-GGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV--G 658 Query: 171 GAGVVAEGVGG 181 G GV GVGG Sbjct: 659 GLGV--PGVGG 667 Score = 41.6 bits (96), Expect = 7e-04 Identities = 47/152 (30%), Positives = 55/152 (36%), Gaps = 7/152 (4%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGG-----AAVVSGGAEADDGSRVVA 107 G VVG V G V G GAG+ V G AA + A G+R Sbjct: 335 GPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARP-G 393 Query: 108 EGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAE 167 GVGG GA G GV GG+ G A V G G V G+ A + A+ Sbjct: 394 VGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAK 453 Query: 168 -EDGGAGVVAEGVGGAAVVSCGAGEFTGANVA 198 G G A AA + G G VA Sbjct: 454 AAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA 485 Score = 40.0 bits (92), Expect = 0.002 Identities = 38/134 (28%), Positives = 46/134 (34%), Gaps = 10/134 (7%) Query: 66 GAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGG 125 G A + AG G GV + AA A+ G+ V GVGGA V G Sbjct: 239 GVAGAAGKAGYPTGTGVGPQAAAAAAA-KAAAKFGAGAAGVLPGVGGAGV-------PGV 290 Query: 126 AGVV--AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAA 183 G + GG+ G + A A G V G G GV GV G Sbjct: 291 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVG 350 Query: 184 VVSCGAGEFTGANV 197 V G GA + Sbjct: 351 VPGAGIPVVPGAGI 364 Score = 38.9 bits (89), Expect = 0.005 Identities = 58/181 (32%), Positives = 70/181 (38%), Gaps = 25/181 (13%) Query: 45 AAEVSEVSGARVVGEELGVVIGAAV-VSCGAGEDGGAGV-----VAEGVGGAAVVSGG-- 96 AA+ ++ VG GV + V V+ G G G GV VA GVG A + G Sbjct: 470 AAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGV 529 Query: 97 -AEADDGSRVVAE-----------GVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAE 144 A A ++V A+ G+ G V G GAGV GVG A V G Sbjct: 530 AAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVG--AGVPGFGA 587 Query: 145 EDGGACVVAEGVGGAAV--VSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEEL 202 G GAAV V GG GG G+ GV GA + A A A L Sbjct: 588 VPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-GVVGAGPAAAAAAAKAAAKAAQFGL 646 Query: 203 V 203 V Sbjct: 647 V 647 Score = 38.1 bits (87), Expect = 0.008 Identities = 52/156 (33%), Positives = 56/156 (35%), Gaps = 17/156 (10%) Query: 44 GAAEVSEVSGARVVGEELGVVIGA--AVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADD 101 G + V G + G LG +GA AV GA GG VA+ GA Sbjct: 59 GGKPLKPVPGG-LAGAGLGAGLGAFPAVTFPGALVPGG---VADAAAAYKAAKAGAGLGG 114 Query: 102 GSRVVAEGVGGAAVVSGGAEEDGGAGVVAG---GVGGAAVVSGGAEEDGGACVVAEGVGG 158 V GV A V G GAGV G GVG V GG GVG Sbjct: 115 VPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARF----PGVGV 170 Query: 159 AAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 V GA G A GVGGA G G F G Sbjct: 171 LPGVPTGA----GVKPKAPGVGGAFAGIPGVGPFGG 202 Score = 38.1 bits (87), Expect = 0.008 Identities = 47/141 (33%), Positives = 57/141 (40%), Gaps = 9/141 (6%) Query: 58 GEELGVVIGAAVVSCGAGEDGGAGVVAEGVG--GAAVVSGGAEADDGSRVVAEGVGGAAV 115 G LG I A + G G G + G G G A +G A G+ V + AA Sbjct: 206 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAA 265 Query: 116 VSGGAEEDGGAGVVAGGVGGAAV--VSGGAEEDGGACVVA--EGVGGAAVVSGGAEEDGG 171 + G AGV+ GVGGA V V G GG V AA + A+ Sbjct: 266 KAAAKFGAGAAGVLP-GVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 324 Query: 172 AGVVAEGVG-GAAVVSC-GAG 190 AG+V G G G VV GAG Sbjct: 325 AGLVPGGPGFGPGVVGVPGAG 345 Score = 36.6 bits (83), Expect = 0.023 Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 10/123 (8%) Query: 68 AVVSCGAGEDG-GAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGA 126 A GAG G G GV G+G A V G G+ V G A+ + A + G A Sbjct: 547 AAAGLGAGIPGLGVGVGVPGLGVGAGVPG---LGVGAGVPGFGAVPGALAAAKAAKYGAA 603 Query: 127 GVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVV-AEGVGGAAVV 185 V G +GG + GG GG VV G AA + A + G+V A G+GG V Sbjct: 604 --VPGVLGGLGAL-GGVGIPGG--VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVG 658 Query: 186 SCG 188 G Sbjct: 659 GLG 661 Score = 34.3 bits (77), Expect = 0.11 Identities = 39/121 (32%), Positives = 42/121 (34%), Gaps = 7/121 (5%) Query: 43 VGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDG 102 +GA GA V G GAG G GV GV A V G G Sbjct: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPG 138 Query: 103 SRV---VAEGVGGAAVVSGGAEEDG---GAGVVAGGVGGAAVVSGGAEEDGGACVVAEGV 156 + V GVG V GG G GV+ G GA V A GGA GV Sbjct: 139 AGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAG-VKPKAPGVGGAFAGIPGV 197 Query: 157 G 157 G Sbjct: 198 G 198 Score = 32.7 bits (73), Expect = 0.33 Identities = 36/109 (33%), Positives = 43/109 (39%), Gaps = 17/109 (15%) Query: 66 GAAV--VSCGAGEDGGAGVVAEGVGG-----AAVVSGGAEADDGSRVVAEGVGGAAVVSG 118 GAAV V G G GG G+ VG AA A+A V A G+GG V Sbjct: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV--- 657 Query: 119 GAEEDGGAGVV-AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGA 166 GG GV GG+GG + G G G + + GGA Sbjct: 658 -----GGLGVPGVGGLGGIPPAAAAKAAKYGV-AARPGFGLSPIFPGGA 700 >gi|126352322 elastin isoform c precursor [Homo sapiens] Length = 692 Score = 44.3 bits (103), Expect = 1e-04 Identities = 52/146 (35%), Positives = 58/146 (39%), Gaps = 19/146 (13%) Query: 66 GAAVVSCGAGEDGGAGV--VAEGVGGAAVVSGGAEADDGSRVVAEGVGGAA--VVSGGAE 121 GAA V G G G GV G+GG A V A A + GAA +V GG Sbjct: 274 GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP- 332 Query: 122 EDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAE---- 177 G GVV GV GA V G G V G+ GAA V G + A A+ Sbjct: 333 -GFGPGVV--GVPGAGVPGVGVPGAGIPVVPGAGIPGAA-VPGVVSPEAAAKAAAKAAKY 388 Query: 178 ------GVGGAAVVSCGAGEFTGANV 197 GVGG GAG F G V Sbjct: 389 GARPGVGVGGIPTYGVGAGGFPGFGV 414 Score = 42.4 bits (98), Expect = 4e-04 Identities = 48/131 (36%), Positives = 57/131 (43%), Gaps = 17/131 (12%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGG 112 GA + G LGV +G + GAG G V GV G V G A ++ G Sbjct: 533 GAGIPG--LGVGVGVPGLGVGAGVPGLG--VGAGVPGFGAVPGALAAAKAAKY------G 582 Query: 113 AAV--VSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDG 170 AAV V GG GG G+ GGV GA + A A G+ GAA + G G Sbjct: 583 AAVPGVLGGLGALGGVGIP-GGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV--G 639 Query: 171 GAGVVAEGVGG 181 G GV GVGG Sbjct: 640 GLGV--PGVGG 648 Score = 42.0 bits (97), Expect = 5e-04 Identities = 46/151 (30%), Positives = 55/151 (36%), Gaps = 6/151 (3%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGG-----AAVVSGGAEADDGSRVVA 107 G VVG V G V G GAG+ V G AA + A G+R Sbjct: 335 GPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARP-G 393 Query: 108 EGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAE 167 GVGG GA G GV GG+ G A V G G V G+ A + A+ Sbjct: 394 VGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAK 453 Query: 168 EDGGAGVVAEGVGGAAVVSCGAGEFTGANVA 198 V GV V+ G G G +A Sbjct: 454 AAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA 484 Score = 40.0 bits (92), Expect = 0.002 Identities = 38/134 (28%), Positives = 46/134 (34%), Gaps = 10/134 (7%) Query: 66 GAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGG 125 G A + AG G GV + AA A+ G+ V GVGGA V G Sbjct: 239 GVAGAAGKAGYPTGTGVGPQAAAAAAA-KAAAKFGAGAAGVLPGVGGAGV-------PGV 290 Query: 126 AGVV--AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAA 183 G + GG+ G + A A G V G G GV GV G Sbjct: 291 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVG 350 Query: 184 VVSCGAGEFTGANV 197 V G GA + Sbjct: 351 VPGAGIPVVPGAGI 364 Score = 38.9 bits (89), Expect = 0.005 Identities = 60/197 (30%), Positives = 72/197 (36%), Gaps = 21/197 (10%) Query: 20 VGLDQNKQAKLKTLIVTEVVVWCVGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGG 79 VG+ QA +V VG A V+ V +G+ G V G G G Sbjct: 440 VGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAP-GVGVAPG 498 Query: 80 AGVVAEGVGGAAVVSGGAEADDGSRVVAE-----------GVGGAAVVSGGAEEDGGAGV 128 GV A G+G V A A ++V A+ G+ G V G GAGV Sbjct: 499 VGV-APGIGPGGVA---AAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGV 554 Query: 129 VAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAV--VSGGAEEDGGAGVVAEGVGGAAVVS 186 GVG A V G G GAAV V GG GG G+ GV GA + Sbjct: 555 PGLGVG--AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-GVVGAGPAA 611 Query: 187 CGAGEFTGANVATEELV 203 A A A LV Sbjct: 612 AAAAAKAAAKAAQFGLV 628 Score = 38.1 bits (87), Expect = 0.008 Identities = 52/156 (33%), Positives = 56/156 (35%), Gaps = 17/156 (10%) Query: 44 GAAEVSEVSGARVVGEELGVVIGA--AVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADD 101 G + V G + G LG +GA AV GA GG VA+ GA Sbjct: 59 GGKPLKPVPGG-LAGAGLGAGLGAFPAVTFPGALVPGG---VADAAAAYKAAKAGAGLGG 114 Query: 102 GSRVVAEGVGGAAVVSGGAEEDGGAGVVAG---GVGGAAVVSGGAEEDGGACVVAEGVGG 158 V GV A V G GAGV G GVG V GG GVG Sbjct: 115 VPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARF----PGVGV 170 Query: 159 AAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 V GA G A GVGGA G G F G Sbjct: 171 LPGVPTGA----GVKPKAPGVGGAFAGIPGVGPFGG 202 Score = 38.1 bits (87), Expect = 0.008 Identities = 47/141 (33%), Positives = 57/141 (40%), Gaps = 9/141 (6%) Query: 58 GEELGVVIGAAVVSCGAGEDGGAGVVAEGVG--GAAVVSGGAEADDGSRVVAEGVGGAAV 115 G LG I A + G G G + G G G A +G A G+ V + AA Sbjct: 206 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAA 265 Query: 116 VSGGAEEDGGAGVVAGGVGGAAV--VSGGAEEDGGACVVA--EGVGGAAVVSGGAEEDGG 171 + G AGV+ GVGGA V V G GG V AA + A+ Sbjct: 266 KAAAKFGAGAAGVLP-GVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 324 Query: 172 AGVVAEGVG-GAAVVSC-GAG 190 AG+V G G G VV GAG Sbjct: 325 AGLVPGGPGFGPGVVGVPGAG 345 Score = 36.6 bits (83), Expect = 0.023 Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 10/123 (8%) Query: 68 AVVSCGAGEDG-GAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGA 126 A GAG G G GV G+G A V G G+ V G A+ + A + G A Sbjct: 528 AAAGLGAGIPGLGVGVGVPGLGVGAGVPG---LGVGAGVPGFGAVPGALAAAKAAKYGAA 584 Query: 127 GVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVV-AEGVGGAAVV 185 V G +GG + GG GG VV G AA + A + G+V A G+GG V Sbjct: 585 --VPGVLGGLGAL-GGVGIPGG--VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVG 639 Query: 186 SCG 188 G Sbjct: 640 GLG 642 Score = 34.3 bits (77), Expect = 0.11 Identities = 39/121 (32%), Positives = 42/121 (34%), Gaps = 7/121 (5%) Query: 43 VGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDG 102 +GA GA V G GAG G GV GV A V G G Sbjct: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPG 138 Query: 103 SRV---VAEGVGGAAVVSGGAEEDG---GAGVVAGGVGGAAVVSGGAEEDGGACVVAEGV 156 + V GVG V GG G GV+ G GA V A GGA GV Sbjct: 139 AGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAG-VKPKAPGVGGAFAGIPGV 197 Query: 157 G 157 G Sbjct: 198 G 198 Score = 32.7 bits (73), Expect = 0.33 Identities = 36/109 (33%), Positives = 43/109 (39%), Gaps = 17/109 (15%) Query: 66 GAAV--VSCGAGEDGGAGVVAEGVGG-----AAVVSGGAEADDGSRVVAEGVGGAAVVSG 118 GAAV V G G GG G+ VG AA A+A V A G+GG V Sbjct: 582 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV--- 638 Query: 119 GAEEDGGAGVV-AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGA 166 GG GV GG+GG + G G G + + GGA Sbjct: 639 -----GGLGVPGVGGLGGIPPAAAAKAAKYGV-AARPGFGLSPIFPGGA 681 >gi|126352700 elastin isoform b precursor [Homo sapiens] Length = 677 Score = 44.3 bits (103), Expect = 1e-04 Identities = 52/146 (35%), Positives = 58/146 (39%), Gaps = 19/146 (13%) Query: 66 GAAVVSCGAGEDGGAGV--VAEGVGGAAVVSGGAEADDGSRVVAEGVGGAA--VVSGGAE 121 GAA V G G G GV G+GG A V A A + GAA +V GG Sbjct: 259 GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP- 317 Query: 122 EDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAE---- 177 G GVV GV GA V G G V G+ GAA V G + A A+ Sbjct: 318 -GFGPGVV--GVPGAGVPGVGVPGAGIPVVPGAGIPGAA-VPGVVSPEAAAKAAAKAAKY 373 Query: 178 ------GVGGAAVVSCGAGEFTGANV 197 GVGG GAG F G V Sbjct: 374 GARPGVGVGGIPTYGVGAGGFPGFGV 399 Score = 42.4 bits (98), Expect = 4e-04 Identities = 48/131 (36%), Positives = 57/131 (43%), Gaps = 17/131 (12%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGG 112 GA + G LGV +G + GAG G V GV G V G A ++ G Sbjct: 518 GAGIPG--LGVGVGVPGLGVGAGVPGLG--VGAGVPGFGAVPGALAAAKAAKY------G 567 Query: 113 AAV--VSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDG 170 AAV V GG GG G+ GGV GA + A A G+ GAA + G G Sbjct: 568 AAVPGVLGGLGALGGVGIP-GGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV--G 624 Query: 171 GAGVVAEGVGG 181 G GV GVGG Sbjct: 625 GLGV--PGVGG 633 Score = 42.0 bits (97), Expect = 5e-04 Identities = 46/151 (30%), Positives = 55/151 (36%), Gaps = 6/151 (3%) Query: 53 GARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGG-----AAVVSGGAEADDGSRVVA 107 G VVG V G V G GAG+ V G AA + A G+R Sbjct: 320 GPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARP-G 378 Query: 108 EGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAE 167 GVGG GA G GV GG+ G A V G G V G+ A + A+ Sbjct: 379 VGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAK 438 Query: 168 EDGGAGVVAEGVGGAAVVSCGAGEFTGANVA 198 V GV V+ G G G +A Sbjct: 439 AAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA 469 Score = 41.2 bits (95), Expect = 0.001 Identities = 54/156 (34%), Positives = 60/156 (38%), Gaps = 22/156 (14%) Query: 44 GAAEVSEVSGARVVGEELGVVIGA--AVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADD 101 G + V G + G LG +GA AV GA +V GV AA A+A Sbjct: 49 GGKPLKPVPGG-LAGAGLGAGLGAFPAVTFPGA-------LVPGGVADAAAAYKAAKAGA 100 Query: 102 GSRVVAEGVGGAAVVSGGAEEDGGAGVVAG---GVGGAAVVSGGAEEDGGACVVAEGVGG 158 G V GVGG V +G GAGV G GVG V GG GVG Sbjct: 101 GLGGVP-GVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR----FPGVG- 154 Query: 159 AAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 V G G A GVGGA G G F G Sbjct: 155 ---VLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGG 187 Score = 40.0 bits (92), Expect = 0.002 Identities = 38/134 (28%), Positives = 46/134 (34%), Gaps = 10/134 (7%) Query: 66 GAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGG 125 G A + AG G GV + AA A+ G+ V GVGGA V G Sbjct: 224 GVAGAAGKAGYPTGTGVGPQAAAAAAA-KAAAKFGAGAAGVLPGVGGAGV-------PGV 275 Query: 126 AGVV--AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAA 183 G + GG+ G + A A G V G G GV GV G Sbjct: 276 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVG 335 Query: 184 VVSCGAGEFTGANV 197 V G GA + Sbjct: 336 VPGAGIPVVPGAGI 349 Score = 38.9 bits (89), Expect = 0.005 Identities = 60/197 (30%), Positives = 72/197 (36%), Gaps = 21/197 (10%) Query: 20 VGLDQNKQAKLKTLIVTEVVVWCVGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGG 79 VG+ QA +V VG A V+ V +G+ G V G G G Sbjct: 425 VGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAP-GVGVAPG 483 Query: 80 AGVVAEGVGGAAVVSGGAEADDGSRVVAE-----------GVGGAAVVSGGAEEDGGAGV 128 GV A G+G V A A ++V A+ G+ G V G GAGV Sbjct: 484 VGV-APGIGPGGVA---AAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGV 539 Query: 129 VAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAV--VSGGAEEDGGAGVVAEGVGGAAVVS 186 GVG A V G G GAAV V GG GG G+ GV GA + Sbjct: 540 PGLGVG--AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-GVVGAGPAA 596 Query: 187 CGAGEFTGANVATEELV 203 A A A LV Sbjct: 597 AAAAAKAAAKAAQFGLV 613 Score = 38.1 bits (87), Expect = 0.008 Identities = 47/141 (33%), Positives = 57/141 (40%), Gaps = 9/141 (6%) Query: 58 GEELGVVIGAAVVSCGAGEDGGAGVVAEGVG--GAAVVSGGAEADDGSRVVAEGVGGAAV 115 G LG I A + G G G + G G G A +G A G+ V + AA Sbjct: 191 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAA 250 Query: 116 VSGGAEEDGGAGVVAGGVGGAAV--VSGGAEEDGGACVVA--EGVGGAAVVSGGAEEDGG 171 + G AGV+ GVGGA V V G GG V AA + A+ Sbjct: 251 KAAAKFGAGAAGVLP-GVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 309 Query: 172 AGVVAEGVG-GAAVVSC-GAG 190 AG+V G G G VV GAG Sbjct: 310 AGLVPGGPGFGPGVVGVPGAG 330 Score = 36.6 bits (83), Expect = 0.023 Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 10/123 (8%) Query: 68 AVVSCGAGEDG-GAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGA 126 A GAG G G GV G+G A V G G+ V G A+ + A + G A Sbjct: 513 AAAGLGAGIPGLGVGVGVPGLGVGAGVPG---LGVGAGVPGFGAVPGALAAAKAAKYGAA 569 Query: 127 GVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVV-AEGVGGAAVV 185 V G +GG + GG GG VV G AA + A + G+V A G+GG V Sbjct: 570 --VPGVLGGLGAL-GGVGIPGG--VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVG 624 Query: 186 SCG 188 G Sbjct: 625 GLG 627 Score = 33.1 bits (74), Expect = 0.25 Identities = 40/119 (33%), Positives = 42/119 (35%), Gaps = 8/119 (6%) Query: 43 VGAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGV-GGAAVVSGGAEADD 101 +GA GA V G GAG G GV GV GA V GA Sbjct: 69 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKP 128 Query: 102 GSRVVAEGVGGAAVVSGGAEEDG---GAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVG 157 G GVG V GG G GV+ G GA V A GGA GVG Sbjct: 129 GK---VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAG-VKPKAPGVGGAFAGIPGVG 183 Score = 32.7 bits (73), Expect = 0.33 Identities = 36/109 (33%), Positives = 43/109 (39%), Gaps = 17/109 (15%) Query: 66 GAAV--VSCGAGEDGGAGVVAEGVGG-----AAVVSGGAEADDGSRVVAEGVGGAAVVSG 118 GAAV V G G GG G+ VG AA A+A V A G+GG V Sbjct: 567 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV--- 623 Query: 119 GAEEDGGAGVV-AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGA 166 GG GV GG+GG + G G G + + GGA Sbjct: 624 -----GGLGVPGVGGLGGIPPAAAAKAAKYGV-AARPGFGLSPIFPGGA 666 >gi|60593038 keratin associated protein 5-4 [Homo sapiens] Length = 288 Score = 44.3 bits (103), Expect = 1e-04 Identities = 42/122 (34%), Positives = 55/122 (45%), Gaps = 15/122 (12%) Query: 70 VSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVV 129 VSCG G GG G GG GG++ GS G G V GG++ GG G Sbjct: 92 VSCG-GSKGGCGSCGGSKGGCGSC-GGSKGGCGS---CGGSKGGCVSCGGSK--GGCGSC 144 Query: 130 AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGA 189 G GG V GG++ G+C ++G G+ GG++ GG G GG SCG Sbjct: 145 GGSKGGC-VSCGGSKGGCGSCGGSKGGCGSC---GGSK--GGCGSCGGSKGGCG--SCGC 196 Query: 190 GE 191 + Sbjct: 197 SQ 198 Score = 42.0 bits (97), Expect = 5e-04 Identities = 42/121 (34%), Positives = 55/121 (45%), Gaps = 15/121 (12%) Query: 71 SCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVA 130 SCG G GG G GG V GG++ GS ++G G+ GG++ GG G Sbjct: 73 SCG-GSKGGYGSCGGSKGGC-VSCGGSKGGCGSCGGSKGGCGSC---GGSK--GGCGSCG 125 Query: 131 GGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAG 190 G GG V GG++ G+C G G V GG++ GG G GG SCG Sbjct: 126 GSKGGC-VSCGGSKGGCGSC---GGSKGGCVSCGGSK--GGCGSCGGSKGGCG--SCGGS 177 Query: 191 E 191 + Sbjct: 178 K 178 Score = 34.7 bits (78), Expect = 0.086 Identities = 37/139 (26%), Positives = 43/139 (30%), Gaps = 25/139 (17%) Query: 72 CGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGG----------------AAV 115 C G G G G GG GG + G G GG V Sbjct: 6 CSGGCGSGCGGCGSGCGGCGSGCGGCGSGCGG--CGSGCGGCGSSCCVPICCCKPVCCCV 63 Query: 116 VSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGA---CVVAEGVGGAAVVSGGAEEDGGA 172 + G G GG G GG GG+ C G G GG++ GG Sbjct: 64 PACSCSSCGSCGGSKGGYGSCGGSKGGCVSCGGSKGGCGSCGGSKGGCGSCGGSK--GGC 121 Query: 173 GVVAEGVGGAAVVSCGAGE 191 G GG VSCG + Sbjct: 122 GSCGGSKGGC--VSCGGSK 138 >gi|239747654 PREDICTED: hypothetical protein XP_002348126 [Homo sapiens] Length = 1032 Score = 43.5 bits (101), Expect = 2e-04 Identities = 55/204 (26%), Positives = 78/204 (38%), Gaps = 17/204 (8%) Query: 37 EVVVWCVGAAEVSEVSGARVVGEELGVVIGA--AVVSCGAGEDGGAGVVAEGVGGAAVVS 94 + +V +G A VS + A V G +V G A+VS G + +G A V S Sbjct: 195 KAIVSGLGKAIVSSLGKAIVSGPGKAIVSGPGKAIVS------GPGKAIVSSLGKAIVCS 248 Query: 95 GGAEADDG-SRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEE--DGGACV 151 G G + + G+G A V G G G G A+VSG + G Sbjct: 249 LGKAIVSGPGKAIVSGLGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKA 308 Query: 152 VAEGVGGAAVVSGGAEEDGGAG-VVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLED 210 + G G A V G G G + G+G A V G +G A + SL Sbjct: 309 IVSGPGKAIVSGPGKAIVSGPGKAIVSGLGKAIVSGPGKAIVSGLGKA-----IVSSLGK 363 Query: 211 MVVAFWGRKVTFGRVVILVEADGK 234 +V+ G+ + G +V GK Sbjct: 364 AIVSGPGKAIVSGPGKAIVSGPGK 387 Score = 42.0 bits (97), Expect = 5e-04 Identities = 56/203 (27%), Positives = 79/203 (38%), Gaps = 15/203 (7%) Query: 37 EVVVWCVGAAEVSEVSGARVVGEELGVVIGA--AVVSCGAGEDGGAGVVAEGVGGAAVVS 94 + +V +G A VS + A V G +V G A+VS G + +G A V S Sbjct: 347 KAIVSGLGKAIVSSLGKAIVSGPGKAIVSGPGKAIVS------GPGKAIVSSLGKAIVCS 400 Query: 95 GGAEADDG-SRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEE--DGGACV 151 G G + + G+G A V G G G G A+VSG + G Sbjct: 401 LGKAIVSGPGKAIVSGLGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKA 460 Query: 152 VAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVATEELVLTFSLEDM 211 + +G A V S G G G G A+VS G G+ A V+ + SL Sbjct: 461 IVSSLGKAIVCSLGKAIVSGPGKAIVSGPGKAIVS-GPGK---AIVSGPGKAIISSLGKA 516 Query: 212 VVAFWGRKVTFGRVVILVEADGK 234 +V G+ + G +V GK Sbjct: 517 IVCSLGKAIVSGPGKAIVSGLGK 539 Score = 39.3 bits (90), Expect = 0.003 Identities = 55/200 (27%), Positives = 71/200 (35%), Gaps = 15/200 (7%) Query: 44 GAAEVSEVSGARVVGEELGVVIG---AAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEAD 100 G A VS A V G +V G A V G G G G A+VSG +A Sbjct: 34 GKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKA- 92 Query: 101 DGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEE--DGGACVVAEGVGG 158 + G G A V G G G G A+VSG + G + G G Sbjct: 93 -----IVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGK 147 Query: 159 AAVVSGGAEEDGGAG-VVAEGVGGAAVVSCGAGEFTG---ANVATEELVLTFSLEDMVVA 214 A V G G G + G G A V G +G A V+ + L +V+ Sbjct: 148 AIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGLGKAIVSGPGKAIVSGLGKAIVS 207 Query: 215 FWGRKVTFGRVVILVEADGK 234 G+ + G +V GK Sbjct: 208 SLGKAIVSGPGKAIVSGPGK 227 Score = 39.3 bits (90), Expect = 0.003 Identities = 60/210 (28%), Positives = 78/210 (37%), Gaps = 19/210 (9%) Query: 44 GAAEVSEVSGARVVGEELGVVIG---AAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEA- 99 G A VS A V G +V G A V G G G G A+VSG +A Sbjct: 282 GKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGLGKAI 341 Query: 100 -DDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAE----EDGGACVVAE 154 + + G+G A V S G G G G A+VSG + G A V + Sbjct: 342 VSGPGKAIVSGLGKAIVSSLGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSSLGKAIVCSL 401 Query: 155 GVG-----GAAVVS--GGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG---ANVATEELVL 204 G G A+VS G A G + G G A V G +G A V+ + Sbjct: 402 GKAIVSGPGKAIVSGLGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAI 461 Query: 205 TFSLEDMVVAFWGRKVTFGRVVILVEADGK 234 SL +V G+ + G +V GK Sbjct: 462 VSSLGKAIVCSLGKAIVSGPGKAIVSGPGK 491 Score = 37.4 bits (85), Expect = 0.013 Identities = 47/161 (29%), Positives = 60/161 (37%), Gaps = 12/161 (7%) Query: 44 GAAEVSEVSGARVVGEELGVVIG---AAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEA- 99 G A VS A V G +V G A V G G G G A+VSG +A Sbjct: 130 GKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGLGKAI 189 Query: 100 -DDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGG 158 + + G+G A V S G G G G A+VSG + + +G Sbjct: 190 VSGPGKAIVSGLGKAIVSSLGKAIVSGPGKAIVSGPGKAIVSGPGK------AIVSSLGK 243 Query: 159 AAVVS-GGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANVA 198 A V S G A G + G+G A V G +G A Sbjct: 244 AIVCSLGKAIVSGPGKAIVSGLGKAIVSGPGKAIVSGPGKA 284 Score = 37.0 bits (84), Expect = 0.017 Identities = 46/157 (29%), Positives = 60/157 (38%), Gaps = 21/157 (13%) Query: 44 GAAEVSEVSGARVVGEELGVV--IGAAVVSCGAGE---DGGAGVVAEGVG-------GAA 91 G A VS A V G ++ +G A+V C G+ G + G+G G A Sbjct: 490 GKAIVSGPGKAIVSGPGKAIISSLGKAIV-CSLGKAIVSGPGKAIVSGLGKAIVSSLGKA 548 Query: 92 VVS--GGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGA 149 +VS G A + + G G A V S G G G G A+VSG + Sbjct: 549 IVSSLGKAIVSSLGKAIVSGPGKAIVSSPGKAIVSGPGKAIVSGPGKAIVSGPGK----- 603 Query: 150 CVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVS 186 + G G A V S G G G G A+VS Sbjct: 604 -AIVSGPGKAIVSSPGKAIVSGPGKAIVSSPGKAIVS 639 Score = 34.7 bits (78), Expect = 0.086 Identities = 54/204 (26%), Positives = 75/204 (36%), Gaps = 25/204 (12%) Query: 37 EVVVWCVGAAEVSEVSGARVVGEELGVV--IGAAVVSCGAGEDGGAGVVAEGVGGAAVVS 94 + +V G A VS A V +V +G A+VS G G G A+VS Sbjct: 651 KAIVSSPGKAIVSSPGKAIVSSPGKAIVSSLGKAIVS-------GPGKAIVSGPGKAIVS 703 Query: 95 GGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAE 154 G +A + G A V S G G G G A+VSG + + Sbjct: 704 GPGKA------IVSSPGKAIVSSLGKAIVSGPGKAIVSSPGKAIVSGPGK------AIVS 751 Query: 155 GVGGAAVVSGGAEEDGGAG-VVAEGVGGAAVVSCGAGEFTG---ANVATEELVLTFSLED 210 G A V S G G G + G A V S G +G A V++ + SL Sbjct: 752 SPGKAIVSSPGKAIVSGPGKAIVSSPGKAIVSSPGKAIVSGLGKAIVSSPGKAIVSSLGK 811 Query: 211 MVVAFWGRKVTFGRVVILVEADGK 234 +V+ G+ + +V GK Sbjct: 812 AIVSSLGKAIVSSLGKAIVSGPGK 835 Score = 34.7 bits (78), Expect = 0.086 Identities = 40/129 (31%), Positives = 48/129 (37%), Gaps = 7/129 (5%) Query: 44 GAAEVSEVSGARVVGEELGVVIG---AAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEA- 99 G A VS A V G +V G A V G G G G A+VSG +A Sbjct: 875 GKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAI 934 Query: 100 -DDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEE--DGGACVVAEGV 156 + + G G A V S G G G G A+VSG + G + G Sbjct: 935 VSGPGKAIVSGPGKAIVSSPGKAIVSGLGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGP 994 Query: 157 GGAAVVSGG 165 G A V S G Sbjct: 995 GKAIVSSPG 1003 Score = 33.9 bits (76), Expect = 0.15 Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 4/102 (3%) Query: 89 GAAVVSGGAEA--DDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEE- 145 G A+VSG +A + + G G A V G G G G A+VSG + Sbjct: 875 GKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAIVSGPGKAI 934 Query: 146 -DGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVS 186 G + G G A V S G G G G A+VS Sbjct: 935 VSGPGKAIVSGPGKAIVSSPGKAIVSGLGKAIVSGPGKAIVS 976 >gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform b [Homo sapiens] Length = 373 Score = 43.5 bits (101), Expect = 2e-04 Identities = 38/134 (28%), Positives = 50/134 (37%), Gaps = 6/134 (4%) Query: 84 AEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGA------EEDGGAGVVAGGVGGAA 137 A G G A + G E + V V AA GA AG GA Sbjct: 141 AAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAP 200 Query: 138 VVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANV 197 +G A G A G G A+ GG GG G A G GGA AG + Sbjct: 201 GAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDR 260 Query: 198 ATEELVLTFSLEDM 211 ++E ++T S+ ++ Sbjct: 261 FSDEQLVTMSVREL 274 Score = 40.4 bits (93), Expect = 0.002 Identities = 40/119 (33%), Positives = 47/119 (39%), Gaps = 26/119 (21%) Query: 44 GAAEVSEVSGARV------VGEELG-------VVIGAAVVSCGAG------EDGGAGVVA 84 GA +++ +GA GEE+G VI AA GAG AG Sbjct: 134 GAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHH 193 Query: 85 EGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGA 143 GA +G A A G A G GG S G GG G GG GG A +GGA Sbjct: 194 HPTAGAPGAAGSAAASAGG---AGGAGGGGPASAG----GGGGGGGGGGGGGAAGAGGA 245 >gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform a [Homo sapiens] Length = 403 Score = 43.5 bits (101), Expect = 2e-04 Identities = 38/134 (28%), Positives = 50/134 (37%), Gaps = 6/134 (4%) Query: 84 AEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGA------EEDGGAGVVAGGVGGAA 137 A G G A + G E + V V AA GA AG GA Sbjct: 141 AAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAP 200 Query: 138 VVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGANV 197 +G A G A G G A+ GG GG G A G GGA AG + Sbjct: 201 GAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDR 260 Query: 198 ATEELVLTFSLEDM 211 ++E ++T S+ ++ Sbjct: 261 FSDEQLVTMSVREL 274 Score = 40.4 bits (93), Expect = 0.002 Identities = 40/119 (33%), Positives = 47/119 (39%), Gaps = 26/119 (21%) Query: 44 GAAEVSEVSGARV------VGEELG-------VVIGAAVVSCGAG------EDGGAGVVA 84 GA +++ +GA GEE+G VI AA GAG AG Sbjct: 134 GAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHH 193 Query: 85 EGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGA 143 GA +G A A G A G GG S G GG G GG GG A +GGA Sbjct: 194 HPTAGAPGAAGSAAASAGG---AGGAGGGGPASAG----GGGGGGGGGGGGGAAGAGGA 245 >gi|5031839 keratin 6A [Homo sapiens] Length = 564 Score = 43.1 bits (100), Expect = 2e-04 Identities = 46/183 (25%), Positives = 69/183 (37%), Gaps = 13/183 (7%) Query: 71 SCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVA 130 S G+G + GGA S GS+ ++ G G A+ GG G A Sbjct: 35 SVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAI-------SGGYGSRA 87 Query: 131 GGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAG 190 GG G G GGA + G+GG A ++GG GG G GG V+ Sbjct: 88 GGSYGFGGAGSGFGFGGGA-GIGFGLGGGAGLAGGF---GGPGFPVCPPGGIQEVTVNQS 143 Query: 191 EFTGANVATEELVLTFSLE--DMVVAFWGRKVTFGRVVILVEADGKVTDGIWVVATKVGL 248 T N+ + + E + + + +F V +E KV + W + + G Sbjct: 144 LLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGT 203 Query: 249 TTL 251 T+ Sbjct: 204 KTV 206 Score = 37.4 bits (85), Expect = 0.013 Identities = 31/95 (32%), Positives = 41/95 (43%), Gaps = 13/95 (13%) Query: 109 GVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVS------GGAEE---DGGACVVAEGVGGA 159 GV + S G+G + G GGA S GG++ GG+C ++ G G Sbjct: 27 GVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSR 86 Query: 160 AVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 A GG+ GGAG G GG A + G G G Sbjct: 87 A---GGSYGFGGAG-SGFGFGGGAGIGFGLGGGAG 117 Score = 34.3 bits (77), Expect = 0.11 Identities = 28/78 (35%), Positives = 36/78 (46%), Gaps = 7/78 (8%) Query: 55 RVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAA 114 R+ GE +G V + V S + GGA V G+G + GG+ GS + GVGG Sbjct: 475 RLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLG----LGGGSSYSYGSGL---GVGGGF 527 Query: 115 VVSGGAEEDGGAGVVAGG 132 S G GG V GG Sbjct: 528 SSSSGRAIGGGLSSVGGG 545 Score = 29.3 bits (64), Expect = 3.6 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 85 EGVG--GAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGG 142 EGVG +VV + G A GVG + GG+ G+G+ GVGG S G Sbjct: 479 EGVGQVNISVVQSTVSSGYGG---ASGVGSGLGLGGGSSYSYGSGL---GVGGGFSSSSG 532 Query: 143 AEEDGGACVVAEG 155 GG V G Sbjct: 533 RAIGGGLSSVGGG 545 >gi|7710121 engrailed homeobox 2 [Homo sapiens] Length = 333 Score = 42.4 bits (98), Expect = 4e-04 Identities = 43/144 (29%), Positives = 64/144 (44%), Gaps = 29/144 (20%) Query: 71 SCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSG-GAEEDGGAGVV 129 +C AG GG G A G GGA+ GG G GG+ + G G+ E Sbjct: 87 TCCAGAGGGRGGGAGGEGGASGAEGGG-----------GAGGSEQLLGSGSREPRQNPPC 135 Query: 130 AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVS--GGAEEDGGAG------VVAEGVGG 181 A G GG + + G++ G +G GG+ +S GGA++ G G + A G+GG Sbjct: 136 APGAGG-PLPAAGSDSPG------DGEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGG 188 Query: 182 A--AVVSCGAGEFTGANVATEELV 203 +V S GAN+ + ++ Sbjct: 189 GDLSVSSDSDSSQAGANLGAQPML 212 Score = 29.6 bits (65), Expect = 2.8 Identities = 34/122 (27%), Positives = 43/122 (35%), Gaps = 29/122 (23%) Query: 75 GEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVG 134 G AG G GG GG A G GGA+ GAE GGAG G Sbjct: 80 GRRKDAGTCCAGAGGGR---GGG---------AGGEGGAS----GAEGGGGAG------G 117 Query: 135 GAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVSCGAGEFTG 194 ++ G+ E A G GG +G +G GG+ +S G G Sbjct: 118 SEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSP-------GDGEGGSKTLSLHGGAKKG 170 Query: 195 AN 196 + Sbjct: 171 GD 172 >gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens] Length = 1047 Score = 42.0 bits (97), Expect = 5e-04 Identities = 41/117 (35%), Positives = 53/117 (45%), Gaps = 11/117 (9%) Query: 69 VVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRV-VAEGVGGAAVVSGGAEEDGGAG 127 +++ AG + G G V G GG +G + RV + + AA G E G AG Sbjct: 1 MMAAEAGSEEG-GPVTAGAGGGGAAAGSSAYPAVCRVKIPAALPVAAAPYPGLVETGVAG 59 Query: 128 VVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAV 184 + GGAA+ S E GA VA +GGA + GG G A GV GAAV Sbjct: 60 TLG---GGAALGS----EFLGAGSVAGALGGAGLTGGGTA--AGVAGAAAGVAGAAV 107 Score = 31.6 bits (70), Expect = 0.73 Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 9/52 (17%) Query: 79 GAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVA 130 GAG VA +GGA + GG A GV GAA GA G +G +A Sbjct: 73 GAGSVAGALGGAGLTGGGTAA---------GVAGAAAGVAGAAVAGPSGDMA 115 >gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens] Length = 483 Score = 41.6 bits (96), Expect = 7e-04 Identities = 35/89 (39%), Positives = 39/89 (43%), Gaps = 7/89 (7%) Query: 93 VSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVV 152 +SGG + G G G A S AE GG G GG GG+A GG G A V Sbjct: 1 MSGGGPSGGGP-----GGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGT-GGGKASVG 54 Query: 153 AEGVG-GAAVVSGGAEEDGGAGVVAEGVG 180 A G G GA+ GG GG G G G Sbjct: 55 AMGGGVGASSSGGGPGGSGGGGSGGPGAG 83 Score = 33.5 bits (75), Expect = 0.19 Identities = 34/101 (33%), Positives = 37/101 (36%), Gaps = 20/101 (19%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G G GG G G A S AE G G GG+A GG GG G Sbjct: 3 GGGPSGGG----PGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGT---GGGKASVGA 55 Query: 133 VGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAG 173 +GG GA GG G GG+ GG GAG Sbjct: 56 MGGGV----GASSSGG------GPGGS---GGGGSGGPGAG 83 Score = 32.3 bits (72), Expect = 0.43 Identities = 26/68 (38%), Positives = 28/68 (41%), Gaps = 4/68 (5%) Query: 125 GAGVVAGGVGGA--AVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGA 182 G G GG GG+ A S AE GG G GG+A GG GG V GG Sbjct: 3 GGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGT--GGGKASVGAMGGGV 60 Query: 183 AVVSCGAG 190 S G G Sbjct: 61 GASSSGGG 68 Score = 32.0 bits (71), Expect = 0.56 Identities = 24/69 (34%), Positives = 26/69 (37%) Query: 66 GAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGG 125 G A S A GG G G GG+A GG S G GA+ GG GG Sbjct: 15 GRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGG 74 Query: 126 AGVVAGGVG 134 G G G Sbjct: 75 GGSGGPGAG 83 Score = 30.8 bits (68), Expect = 1.2 Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 8/72 (11%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G G GG G A G GG +GG +A G A G G A SGG G G G Sbjct: 29 GGGGGGGPGGSASGPGG----TGGGKASVG----AMGGGVGASSSGGGPGGSGGGGSGGP 80 Query: 133 VGGAAVVSGGAE 144 G + G + Sbjct: 81 GAGTSFPPPGVK 92 >gi|195972866 keratin 10 [Homo sapiens] Length = 584 Score = 41.6 bits (96), Expect = 7e-04 Identities = 35/108 (32%), Positives = 44/108 (40%), Gaps = 14/108 (12%) Query: 71 SCGAGEDGG-AGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVV 129 S G G GG G G GG + G + G + G GG++ G GG G Sbjct: 482 SSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGG-- 539 Query: 130 AGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAE 177 GG GG + SGG GG G GG + S G + +G V E Sbjct: 540 -GGYGGGS--SGGGSSSGG------GYGGGS--SSGGHKSSSSGSVGE 576 Score = 41.2 bits (95), Expect = 0.001 Identities = 39/123 (31%), Positives = 45/123 (36%), Gaps = 24/123 (19%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G G GG G GG GG + GS SGG G G GG Sbjct: 455 GEGSSGGGGRGGGSFGGGY---GGGSSGGGS-------------SGGGHGGGHGGSSGGG 498 Query: 133 VGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDG-GAGVVAEGVGGAAVVSCGAGE 191 GG + SGG GG G G ++ GG+ G G G G GG S G G Sbjct: 499 YGGGS--SGGGSSGGGY-----GGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGS 551 Query: 192 FTG 194 +G Sbjct: 552 SSG 554 Score = 38.9 bits (89), Expect = 0.005 Identities = 32/99 (32%), Positives = 36/99 (36%), Gaps = 7/99 (7%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGAGVVAGG 132 G G GG G G GG S G GS GG GG+ G G +GG Sbjct: 474 GGGSSGG-GSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGG---YGGGSSSGGHGGSSSGG 529 Query: 133 VGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGG 171 GG + GG GG+ GG GG GG Sbjct: 530 YGGGSSGGGGGGYGGGSSGGGSSSGGG---YGGGSSSGG 565 Score = 38.5 bits (88), Expect = 0.006 Identities = 41/126 (32%), Positives = 49/126 (38%), Gaps = 17/126 (13%) Query: 71 SCGAGEDGGAGVVAEGVGGAAV---VSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGG-- 125 S G G GG G G GG + SGG G GG + SGG GG Sbjct: 458 SSGGGGRGG-GSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGS--SGGGSSGGGYG 514 Query: 126 AGVVAGGVGGAAV--VSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAA 183 G +GG GG++ GG+ GG G GG + SGG GG GG Sbjct: 515 GGSSSGGHGGSSSGGYGGGSSGGGGG-----GYGGGS--SGGGSSSGGGYGGGSSSGGHK 567 Query: 184 VVSCGA 189 S G+ Sbjct: 568 SSSSGS 573 Score = 35.4 bits (80), Expect = 0.050 Identities = 42/149 (28%), Positives = 56/149 (37%), Gaps = 16/149 (10%) Query: 73 GAGEDGGAGVVA------EGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGGA 126 G G GG GV + +G G SGG SR G G G + GG Sbjct: 22 GGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSR----GSSGGGCFGGSS---GGY 74 Query: 127 GVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVSGGAEEDGGAGVVAEGVGGAAVVS 186 G + G GG+ S G+ GG+ + G G S G GG G G GG Sbjct: 75 GGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGG 134 Query: 187 CGAGEFTGANVATEELVLTFSLEDMVVAF 215 G G ++ E V +L D + ++ Sbjct: 135 FGG---DGGLLSGNEKVTMQNLNDRLASY 160 Score = 35.4 bits (80), Expect = 0.050 Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 2/83 (2%) Query: 66 GAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRVVAEGVGGAAVVSGGAEEDGG 125 G++ C G GG G + GG+ S G+ + GS + G G S G GG Sbjct: 60 GSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGG 119 Query: 126 AGVVAGGVGGAAVVSGGAEEDGG 148 G GG GG GG DGG Sbjct: 120 GGFGGGGFGGG--FGGGFGGDGG 140 Score = 30.8 bits (68), Expect = 1.2 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 20/93 (21%) Query: 104 RVVAEGVGGAAVVSGGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGACVVAEGVGGAAVVS 163 R + EG G SGG GG+ GG GG + SGG GG G GG+ S Sbjct: 450 RSLLEGEGS----SGGGGRGGGS--FGGGYGGGS--SGGGSSGGGH---GGGHGGS---S 495 Query: 164 GGAEEDGGAGVVAEGVGGAAVVSCGAGEFTGAN 196 GG G +G GG++ G G +G + Sbjct: 496 GGGYGGGSSG------GGSSGGGYGGGSSSGGH 522 >gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] Length = 572 Score = 41.6 bits (96), Expect = 7e-04 Identities = 29/82 (35%), Positives = 34/82 (41%), Gaps = 2/82 (2%) Query: 101 DGSRVVAEGVGGAAVVSGGAEEDGGA--GVVAGGVGGAAVVSGGAEEDGGACVVAEGVGG 158 D S + GG G A +G A GV G GG VV G+ ED + G G Sbjct: 17 DSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAGEPGSAG 76 Query: 159 AAVVSGGAEEDGGAGVVAEGVG 180 A G GG V A+GVG Sbjct: 77 AGGDVNGTAAVGGLVVSAQGVG 98 Score = 40.4 bits (93), Expect = 0.002 Identities = 32/88 (36%), Positives = 39/88 (44%), Gaps = 5/88 (5%) Query: 73 GAGEDGGAGVVAEGVGGAAVVSGGAEADDGSRV--VAEGVGGAA-VVSGGAEEDGGAGVV 129 G D AG + G GG + +GGA +G V V G GG VV G+ ED + Sbjct: 13 GPRPDSSAGGSSAGGGGGS--AGGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAG 70 Query: 130 AGGVGGAAVVSGGAEEDGGACVVAEGVG 157 G GA G GG V A+GVG Sbjct: 71 EPGSAGAGGDVNGTAAVGGLVVSAQGVG 98 Score = 33.1 bits (74), Expect = 0.25 Identities = 26/68 (38%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 44 GAAEVSEVSGARVVGEELGVVIGAAVVSCGAGEDGGAGVVAEGVGGAAVVSGGAEADDGS 103 G A SE G V G G G VV G+GED + G GA G A G Sbjct: 33 GGAAPSE--GPAVGGVPGGAGGGGGVVGAGSGEDNRSSAGEPGSAGAGGDVNGTAAVGGL 90 Query: 104 RVVAEGVG 111 V A+GVG Sbjct: 91 VVSAQGVG 98 Score = 31.2 bits (69), Expect = 0.95 Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 4/67 (5%) Query: 118 GGAEEDGGAGVVAGGVGGAAVVSGGAEEDGGAC--VVAEGVGGAAVVSGGAEEDGGAGVV 175 G + G AGG GG+A G A +G A V GG VV G+ ED + Sbjct: 13 GPRPDSSAGGSSAGGGGGSA--GGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAG 70 Query: 176 AEGVGGA 182 G GA Sbjct: 71 EPGSAGA 77 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.134 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,884,892 Number of Sequences: 37866 Number of extensions: 500839 Number of successful extensions: 6308 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 122 Number of HSP's successfully gapped in prelim test: 244 Number of HSP's that attempted gapping in prelim test: 2525 Number of HSP's gapped (non-prelim): 1873 length of query: 261 length of database: 18,247,518 effective HSP length: 100 effective length of query: 161 effective length of database: 14,460,918 effective search space: 2328207798 effective search space used: 2328207798 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.