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Search of human proteins with 169164915
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens]
(195 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens] 424 e-119
gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens] 419 e-118
gi|4507425 teratocarcinoma-derived growth factor 1 [Homo sapiens] 258 2e-69
gi|14211837 cryptic [Homo sapiens] 76 2e-14
gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens] 76 2e-14
gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens] 44 9e-05
gi|148833508 notch1 preproprotein [Homo sapiens] 43 1e-04
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 41 6e-04
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 40 0.001
gi|134244285 Notch homolog 3 [Homo sapiens] 40 0.002
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 40 0.002
gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens] 40 0.002
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 38 0.005
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 37 0.008
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 37 0.008
gi|148886654 polydom [Homo sapiens] 37 0.008
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 37 0.011
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 37 0.014
gi|24430141 fibrillin 1 precursor [Homo sapiens] 36 0.018
gi|24041035 notch 2 preproprotein [Homo sapiens] 36 0.018
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti... 36 0.018
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] 36 0.018
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 36 0.018
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 36 0.018
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 36 0.018
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 36 0.018
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 36 0.018
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 36 0.018
gi|55770876 notch4 preproprotein [Homo sapiens] 35 0.031
gi|126012562 low density lipoprotein-related protein 1 [Homo sap... 35 0.040
>gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens]
Length = 195
Score = 424 bits (1089), Expect = e-119
Identities = 195/195 (100%), Positives = 195/195 (100%)
Query: 1 MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE 60
MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE
Sbjct: 1 MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE 60
Query: 61 GDLAFRDDSIQPQEEPAICPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF 120
GDLAFRDDSIQPQEEPAICPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF
Sbjct: 61 GDLAFRDDSIQPQEEPAICPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF 120
Query: 121 YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP 180
YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP
Sbjct: 121 YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP 180
Query: 181 RTPELPPSACTTFIC 195
RTPELPPSACTTFIC
Sbjct: 181 RTPELPPSACTTFIC 195
>gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens]
Length = 195
Score = 419 bits (1077), Expect = e-118
Identities = 194/195 (99%), Positives = 194/195 (99%)
Query: 1 MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE 60
MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE
Sbjct: 1 MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE 60
Query: 61 GDLAFRDDSIQPQEEPAICPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF 120
GDLAFRDDSIQPQEEPAI PRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF
Sbjct: 61 GDLAFRDDSIQPQEEPAIRPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF 120
Query: 121 YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP 180
YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP
Sbjct: 121 YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP 180
Query: 181 RTPELPPSACTTFIC 195
RTPELPPSACTTFIC
Sbjct: 181 RTPELPPSACTTFIC 195
>gi|4507425 teratocarcinoma-derived growth factor 1 [Homo sapiens]
Length = 188
Score = 258 bits (660), Expect = 2e-69
Identities = 120/139 (86%), Positives = 123/139 (88%)
Query: 54 EVSRVKEGDLAFRDDSIQPQEEPAICPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSF 113
E +R G LAFRDDSI PQEEPAI PRSSQ VPPMGIQ SKE NRTCCLNGGTCMLGSF
Sbjct: 35 EFARPSRGYLAFRDDSIWPQEEPAIRPRSSQRVPPMGIQHSKELNRTCCLNGGTCMLGSF 94
Query: 114 CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVM 173
CAC PSFYG NCEH VRKENCGSVPHDT LPKKCS+CKCWHGQLRCFPQAFLPGCDGLVM
Sbjct: 95 CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVM 154
Query: 174 DEHLMAPRTPELPPSACTT 192
DEHL+A RTPELPPSA TT
Sbjct: 155 DEHLVASRTPELPPSARTT 173
>gi|14211837 cryptic [Homo sapiens]
Length = 223
Score = 75.9 bits (185), Expect = 2e-14
Identities = 31/69 (44%), Positives = 38/69 (55%)
Query: 101 CCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCF 160
CC NGGTC+LGSFC C F G CEH R+ CG++ H + C +C+C G L C
Sbjct: 90 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149
Query: 161 PQAFLPGCD 169
P CD
Sbjct: 150 PLQTPDRCD 158
>gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens]
Length = 223
Score = 75.9 bits (185), Expect = 2e-14
Identities = 31/69 (44%), Positives = 38/69 (55%)
Query: 101 CCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCF 160
CC NGGTC+LGSFC C F G CEH R+ CG++ H + C +C+C G L C
Sbjct: 90 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149
Query: 161 PQAFLPGCD 169
P CD
Sbjct: 150 PLQTPDRCD 158
>gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]
Length = 379
Score = 43.9 bits (102), Expect = 9e-05
Identities = 31/98 (31%), Positives = 36/98 (36%), Gaps = 32/98 (32%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEH-----------------------GVRKENC--GS 136
C+NGG C+ FC C P FYG NC+ G+ E C
Sbjct: 218 CMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISK 277
Query: 137 VPHDTRLPKKC---SMCKC---WHGQLRCFPQAFLPGC 168
P R KC S CKC + G L C PGC
Sbjct: 278 CPQPCRNGGKCIGKSKCKCSKGYQGDL-CSKPVCEPGC 314
Score = 40.8 bits (94), Expect = 7e-04
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Query: 79 CPRSSQLVPPMGIQDSKEPNRTC---CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG 135
C + + P G++ + C C NGG C+ S C C + G C V + CG
Sbjct: 256 CFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCG 315
Query: 136 SVPHDT-RLPKKCSMCKCWHGQ 156
+ H T P KC + WHG+
Sbjct: 316 A--HGTCHEPNKCQCQEGWHGR 335
Score = 30.0 bits (66), Expect = 1.3
Identities = 12/33 (36%), Positives = 15/33 (45%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC 134
C NGG C C C F+G +CE + C
Sbjct: 186 CRNGGFCNERRICECPDGFHGPHCEKALCTPRC 218
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 43.1 bits (100), Expect = 1e-04
Identities = 35/116 (30%), Positives = 47/116 (40%), Gaps = 21/116 (18%)
Query: 72 PQEEPAICPRSSQLVP-PMGIQDSKEP-----NRTCCLNGGTCM--LGSF-CACLPSFYG 122
P CPR +Q V + + D P C N GTC+ +G + C C P F G
Sbjct: 1202 PNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVG 1261
Query: 123 WNCEHGVRKENCGSVPHDTRLPKKCSM--------CKCWHGQLRCFPQAFLPGCDG 170
CE V + C S P D R + C C+ H RC ++ + GC G
Sbjct: 1262 ERCEGDVNE--CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRC--ESVINGCKG 1313
Score = 39.7 bits (91), Expect = 0.002
Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 14/77 (18%)
Query: 102 CLNGGTCMLG--SF-CACLPSFYGWNCEHGVRKENCGSVP--HDTRLPKKCSMCKCWHGQ 156
C NGGTC+ G SF C C P F G C+H V + C S P H C +C
Sbjct: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNE--CDSQPCLHGGTCQDGCGSYRC---- 1045
Query: 157 LRCFPQAFL-PGCDGLV 172
PQ + P C LV
Sbjct: 1046 --TCPQGYTGPNCQNLV 1060
Score = 36.6 bits (83), Expect = 0.014
Identities = 24/61 (39%), Positives = 29/61 (47%), Gaps = 9/61 (14%)
Query: 93 DSKEPNRTCCLNGGTCMLG---SFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSM 149
D PN C NGG+C G +FC CLP F G CE + + C S P R C+
Sbjct: 909 DDCRPNP--CHNGGSCTDGINTAFCDCLPGFRGTFCEEDINE--CASDP--CRNGANCTD 962
Query: 150 C 150
C
Sbjct: 963 C 963
Score = 36.2 bits (82), Expect = 0.018
Identities = 16/32 (50%), Positives = 18/32 (56%), Gaps = 4/32 (12%)
Query: 102 CLNGGTCM----LGSFCACLPSFYGWNCEHGV 129
C NGGTC + CACLP F G NCE +
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258
Score = 34.3 bits (77), Expect = 0.069
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 7/56 (12%)
Query: 102 CLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP--HDTRLPKKCSMCKC 152
C N TC+ +G F C C+P + G +CE V + C S P H+ R K + +C
Sbjct: 461 CQNDATCLDQIGEFQCICMPGYEGVHCE--VNTDECASSPCLHNGRCLDKINEFQC 514
Score = 33.1 bits (74), Expect = 0.15
Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 8/65 (12%)
Query: 102 CLNGGTCM---LGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLR 158
C NGG C+ C C PSF+G C V + CG P L + C G R
Sbjct: 149 CANGGQCLPFEASYICHCPPSFHGPTCRQDVNE--CGQKP---GLCRHGGTCHNEVGSYR 203
Query: 159 CFPQA 163
C +A
Sbjct: 204 CVCRA 208
Score = 33.1 bits (74), Expect = 0.15
Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 14/72 (19%)
Query: 93 DSKEPNRTCCLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSM 149
D E + CL+GGTC GS+ C C + G NC++ V C S P +
Sbjct: 1021 DVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHW--CDSSPCK-------NG 1071
Query: 150 CKCW--HGQLRC 159
KCW H Q RC
Sbjct: 1072 GKCWQTHTQYRC 1083
Score = 33.1 bits (74), Expect = 0.15
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 9/60 (15%)
Query: 88 PMGIQDSKEPN--RTC----CLNGGTCMLG---SFCACLPSFYGWNCEHGVRKENCGSVP 138
P G + + N RTC CLNGGTC+ G C CL F G C+ G P
Sbjct: 1337 PAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNP 1396
Score = 32.3 bits (72), Expect = 0.26
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 102 CLNGGTCM---LGSFCACLPSFYGWNCEHGVRKENCGSVP 138
C+NGGTC G C C F G NC+ + + C S P
Sbjct: 762 CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINE--CASNP 799
Score = 32.3 bits (72), Expect = 0.26
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 8/42 (19%)
Query: 102 CLNGGTCMLGS------FCACLPSFYGWNCEHGVRKENCGSV 137
C NGGTC + S C C F G CE+ R CGS+
Sbjct: 1316 CKNGGTCAVASNTARGFICKCPAGFEGATCENDAR--TCGSL 1355
Score = 28.9 bits (63), Expect = 2.9
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 5/40 (12%)
Query: 102 CLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
C NG TC LG + C C+ ++G NC + + C S P
Sbjct: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI--DECLSHP 1191
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 41.2 bits (95), Expect = 6e-04
Identities = 35/105 (33%), Positives = 44/105 (41%), Gaps = 21/105 (20%)
Query: 78 ICPRS-SQLVPPMGIQDSKEP--NRTCCLNGGTCMLGS----FCACLPSFYGWNCEHGVR 130
ICPR + I + EP N CLNGG C+ G C CLP F G CE +
Sbjct: 1104 ICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININ 1163
Query: 131 KENCGSVP--HDTRLPKKCS--MCKC---WHG-----QLRCFPQA 163
+ C S P H + +CKC W G +L C P +
Sbjct: 1164 E--CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNS 1206
Score = 28.9 bits (63), Expect = 2.9
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 7/41 (17%)
Query: 94 SKEPNRTCCLNGGTCMLGS---FCACLPSFYGWNCEHGVRK 131
S EP C N GTC+ + FC C P ++G CE V K
Sbjct: 933 SSEP----CKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNK 969
Score = 27.3 bits (59), Expect = 8.4
Identities = 12/31 (38%), Positives = 14/31 (45%), Gaps = 3/31 (9%)
Query: 102 CLNGGTCMLGSF---CACLPSFYGWNCEHGV 129
C NGG C + C CLP + G C V
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV 2914
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 40.4 bits (93), Expect = 0.001
Identities = 29/81 (35%), Positives = 34/81 (41%), Gaps = 14/81 (17%)
Query: 102 CLNGGTC-MLGSFCACLPSFYGWNCEHGV----------RKENCGSVPHDTRLPKKCSMC 150
C NGGTC + C C P G NCE G +K NC + RL C
Sbjct: 570 CQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCD 629
Query: 151 KCWHGQ---LRCFPQAFLPGC 168
+G+ L C P AF PGC
Sbjct: 630 PGLYGRFCHLTCPPWAFGPGC 650
Score = 35.8 bits (81), Expect = 0.024
Identities = 33/98 (33%), Positives = 40/98 (40%), Gaps = 16/98 (16%)
Query: 65 FRDDSIQPQEEPAICPRSSQLVPPMGIQDSK---EPNRTC--CLNGGTCMLG-SFCACLP 118
F+DD + EE A L D + + TC C NGGTC+LG C C
Sbjct: 485 FQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPE 544
Query: 119 SFYGWNCEHGVRKENCGSVPHDTRLPKKCSM-CKCWHG 155
+ G C E C P DT K CS C C +G
Sbjct: 545 GWTGLIC-----NETC---PPDT-FGKNCSFSCSCQNG 573
Score = 33.9 bits (76), Expect = 0.090
Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 15/88 (17%)
Query: 99 RTCCLNGGTCM-LGSFCACLPSFYGWNCEH----GVRKENC-------GSVPHDTRLPKK 146
R C G C + C C P F G CE G E+C G P
Sbjct: 1131 RCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT 1190
Query: 147 CSMCKCWHG---QLRCFPQAFLPGCDGL 171
CS +HG Q RC P + PGC+ L
Sbjct: 1191 CSCAAGYHGPSCQQRCPPGRYGPGCEQL 1218
Score = 33.1 bits (74), Expect = 0.15
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 6/67 (8%)
Query: 94 SKEPNRTCCLNGGTCMLGSF--CACLPSFYGWNCEHGV---RKENCGSVPHDTRLPKKCS 148
S E + + C +GG C+ GS C C P F G C++ V R N G P
Sbjct: 125 SAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGS-Y 183
Query: 149 MCKCWHG 155
+C+C G
Sbjct: 184 LCECKPG 190
Score = 32.7 bits (73), Expect = 0.20
Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 21/119 (17%)
Query: 76 PAICPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGS-FCACLPSFYGWNCEHGVRKENC 134
P Q V P G R C N G C + C+C P + G++C+ R +
Sbjct: 806 PGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQ---RACDT 862
Query: 135 GSVPHDTRLPKKCS-----------MCKCWHGQL--RCFPQA----FLPGCDGLVMDEH 176
G D P CS +C C G + RC Q F PGC+ +H
Sbjct: 863 GHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQH 921
Score = 32.3 bits (72), Expect = 0.26
Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 14/102 (13%)
Query: 81 RSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGS-FCACLPSFYGWNCEH----GVRKENCG 135
R +L P G + C N TC + C C P FYG CEH G C
Sbjct: 1329 RHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQ 1388
Query: 136 SV---PHDTRLPKKCSMCKC---WHG---QLRCFPQAFLPGC 168
+ H C C +HG + C P +F GC
Sbjct: 1389 GLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGC 1430
Score = 29.6 bits (65), Expect = 1.7
Identities = 22/84 (26%), Positives = 31/84 (36%), Gaps = 20/84 (23%)
Query: 102 CLNGGTC------------MLGSFC--ACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKC 147
C NG +C +G C AC YG NC H +N G+ + C
Sbjct: 1005 CFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC---DPVSGHC 1061
Query: 148 SMCKCWHG---QLRCFPQAFLPGC 168
+ + W G + C P+ GC
Sbjct: 1062 ACPEGWAGLACEKECLPRDVRAGC 1085
Score = 28.5 bits (62), Expect = 3.8
Identities = 21/68 (30%), Positives = 25/68 (36%), Gaps = 8/68 (11%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG-SVPHDTRLPKKCSMCKCW------- 153
C TC +G C + G C G + E+CG P T S C C
Sbjct: 695 CWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGV 754
Query: 154 HGQLRCFP 161
GQ RC P
Sbjct: 755 TGQCRCPP 762
Score = 28.5 bits (62), Expect = 3.8
Identities = 14/40 (35%), Positives = 18/40 (45%), Gaps = 1/40 (2%)
Query: 88 PMGIQDSKEPNRTCCLNGGTC-MLGSFCACLPSFYGWNCE 126
P G+ + C NGGTC + CAC + G CE
Sbjct: 1034 PAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACE 1073
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 39.7 bits (91), Expect = 0.002
Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 19/102 (18%)
Query: 92 QDSKEPNRTCCLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCS 148
QD + + CLNGG+C +GSF C+CLP F G C V D L C
Sbjct: 848 QDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDV----------DECLSNPCG 897
Query: 149 MCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAPRTPELPPSAC 190
C + F PG G ++ L P+ PS+C
Sbjct: 898 PGTC-TDHVASFTCTCPPGYGGFHCEQDL-----PDCSPSSC 933
Score = 37.4 bits (85), Expect = 0.008
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 102 CLNGGTC---MLGSFCACLPSFYGWNCEHGVRKENCGSVP 138
C +GGTC M G C CLP + G NCE V + C S P
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDV--DECASQP 1130
Score = 37.0 bits (84), Expect = 0.011
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 16/74 (21%)
Query: 92 QDSKEPNRTCCLNGGTCMLG--SF-CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKC- 147
QD + + + C NGGTC+ G SF C C P + G +C+H D L + C
Sbjct: 923 QDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEA----------DPCLSRPCL 972
Query: 148 --SMCKCWHGQLRC 159
+C H RC
Sbjct: 973 HGGVCSAAHPGFRC 986
Score = 36.2 bits (82), Expect = 0.018
Identities = 18/32 (56%), Positives = 18/32 (56%), Gaps = 4/32 (12%)
Query: 102 CLNGGTCM----LGSFCACLPSFYGWNCEHGV 129
C NGGTC L CACLP F G NCE V
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNV 237
Score = 30.8 bits (68), Expect = 0.76
Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 3/38 (7%)
Query: 102 CLNGGTC--MLGSF-CACLPSFYGWNCEHGVRKENCGS 136
CL+ GTC ++G F C C P + G CE + + G+
Sbjct: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGA 1213
Score = 29.6 bits (65), Expect = 1.7
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 10/64 (15%)
Query: 102 CLNGGTCML---GSFCACLPSFYGWNCEHGVRKENCGSVP--HDTRLPKKCSMCKC---W 153
CL+GG C G C CL SF G C+ V + C P + R + + C C W
Sbjct: 971 CLHGGVCSAAHPGFRCTCLESFTGPQCQTLV--DWCSRQPCQNGGRCVQTGAYCLCPPGW 1028
Query: 154 HGQL 157
G+L
Sbjct: 1029 SGRL 1032
Score = 29.3 bits (64), Expect = 2.2
Identities = 26/72 (36%), Positives = 29/72 (40%), Gaps = 21/72 (29%)
Query: 102 CLNGGTCM---LGSFCACLPSFYGWN-----------CEHGVRKENCGSVPHDTRLPKKC 147
C GGTC +G C C P G CEHG R C S P +LP C
Sbjct: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGR---CESAP--GQLP-VC 796
Query: 148 SMCKCWHGQLRC 159
S + W G RC
Sbjct: 797 SCPQGWQGP-RC 807
Score = 29.3 bits (64), Expect = 2.2
Identities = 12/30 (40%), Positives = 18/30 (60%), Gaps = 1/30 (3%)
Query: 98 NRTCCLNGGTCM-LGSFCACLPSFYGWNCE 126
+R C NGG C+ G++C C P + G C+
Sbjct: 1005 SRQPCQNGGRCVQTGAYCLCPPGWSGRLCD 1034
Score = 28.1 bits (61), Expect = 4.9
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 3/31 (9%)
Query: 102 CLNGGTCMLG---SFCACLPSFYGWNCEHGV 129
CLNGGTC+ G C C P + G C V
Sbjct: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV 275
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 39.7 bits (91), Expect = 0.002
Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 16/84 (19%)
Query: 98 NRTCCLNGGTCM-LGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSM-CKCWHG 155
NR C NG C + C C F GW CE E C H K C + C+C HG
Sbjct: 144 NRCQCQNGALCNPITGACVCAAGFRGWRCE-----ELCAPGTHG----KGCQLPCQCRHG 194
Query: 156 QLRCFPQA----FLPGCDGLVMDE 175
C P+A PG G+ +E
Sbjct: 195 -ASCDPRAGECLCAPGYTGVYCEE 217
Score = 27.7 bits (60), Expect = 6.5
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 11/57 (19%)
Query: 106 GTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCS-MCKCWHGQLRCFP 161
G C+ C C P + G +C G ++ G PH CS C+C +G L C P
Sbjct: 110 GRCVSPDTCHCEPGWGGPDCSSGCDSDHWG--PH-------CSNRCQCQNGAL-CNP 156
Score = 27.7 bits (60), Expect = 6.5
Identities = 12/31 (38%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 98 NRTC-CLNGGTCM-LGSFCACLPSFYGWNCE 126
N +C C NG C + C+C P + G CE
Sbjct: 490 NESCTCANGAACSPIDGSCSCTPGWLGDTCE 520
>gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens]
Length = 4349
Score = 39.7 bits (91), Expect = 0.002
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 10/65 (15%)
Query: 98 NRTCCLNGGTCM----LGSFCACLPSFYGWNCEHGVRKENCGSVP----HDTRLPKKCSM 149
++ CLNGG C G C C P F G +CE G +ENC P L K +
Sbjct: 3952 SQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQG--RENCTFAPCLEGGTCILSPKGAS 4009
Query: 150 CKCWH 154
C C H
Sbjct: 4010 CNCPH 4014
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 38.1 bits (87), Expect = 0.005
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 10/66 (15%)
Query: 88 PMGIQDSKEPNRTCCLNGGTCML-GSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKK 146
P G+ N C NGGTC+ C C P F G +C+ + G K+
Sbjct: 568 PEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYG---------KR 618
Query: 147 CSMCKC 152
C CKC
Sbjct: 619 CVPCKC 624
Score = 30.8 bits (68), Expect = 0.76
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 16/66 (24%)
Query: 114 CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQL--------RCFPQAFL 165
C+CLP + G +C E+C P DT P C C HG + +C P
Sbjct: 380 CSCLPGWAGLHC-----NESC---PQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTG 431
Query: 166 PGCDGL 171
P C L
Sbjct: 432 PHCASL 437
Score = 27.7 bits (60), Expect = 6.5
Identities = 20/85 (23%), Positives = 33/85 (38%), Gaps = 9/85 (10%)
Query: 106 GTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFL 165
G C+ + C C+P + G +C C + K CS C + C P++ +
Sbjct: 112 GRCVAPNQCQCVPGWRGDDC-----SSECAPGMWGPQCDKPCS---CGNNS-SCDPKSGV 162
Query: 166 PGCDGLVMDEHLMAPRTPELPPSAC 190
C + + + P TP AC
Sbjct: 163 CSCPSGLQPPNCLQPCTPGYYGPAC 187
>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
Length = 814
Score = 37.4 bits (85), Expect = 0.008
Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 1/52 (1%)
Query: 144 PKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAPRTPELPPSACTTFIC 195
P C+ C C G C PQA LP C G + P ACTT C
Sbjct: 111 PDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYG-NGETFSPDACTTCRC 161
Score = 29.6 bits (65), Expect = 1.7
Identities = 9/20 (45%), Positives = 12/20 (60%)
Query: 147 CSMCKCWHGQLRCFPQAFLP 166
C +C CW G + C P+A P
Sbjct: 743 CHLCLCWEGSVSCEPKACAP 762
Score = 28.5 bits (62), Expect = 3.8
Identities = 29/119 (24%), Positives = 45/119 (37%), Gaps = 31/119 (26%)
Query: 75 EPAICPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC 134
+P CPR+ P G TCC N C+ C G ++
Sbjct: 575 QPRPCPRAPCAHPLPG---------TCCPND--------CS--------GCAFGGKEYPS 609
Query: 135 GS-VPHDTRLPKKCSMCKCWHGQLRCFPQAFLP-GCDGLVMDEHLMAPRTPELP-PSAC 190
G+ PH + C +C+C G ++C + +P C V+ P+ P P P+ C
Sbjct: 610 GADFPHPS---DPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAPAGC 665
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 37.4 bits (85), Expect = 0.008
Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 1/52 (1%)
Query: 144 PKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAPRTPELPPSACTTFIC 195
P C+ C C G C PQA LP C G + P ACTT C
Sbjct: 111 PDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYG-NGETFSPDACTTCRC 161
Score = 29.6 bits (65), Expect = 1.7
Identities = 9/20 (45%), Positives = 12/20 (60%)
Query: 147 CSMCKCWHGQLRCFPQAFLP 166
C +C CW G + C P+A P
Sbjct: 682 CHLCLCWEGSVSCEPKACAP 701
Score = 28.9 bits (63), Expect = 2.9
Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 17/81 (20%)
Query: 93 DSKEPNRTCCLNGGTCMLGSF------CA--------CLPSFYGWNCEHGVRKENCGSVP 138
D +EP C GG G C+ C P+ G HGV + ++P
Sbjct: 734 DPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRY-HGVTTASGETLP 792
Query: 139 HDTRLPKKCSMCKCWHGQLRC 159
L CS+C C G +RC
Sbjct: 793 DP--LDPTCSLCTCQEGSMRC 811
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 37.4 bits (85), Expect = 0.008
Identities = 25/87 (28%), Positives = 32/87 (36%), Gaps = 4/87 (4%)
Query: 72 PQEEPAICPRSSQLVPPMGIQDSKEPNRTC---CLNGGTCMLGSFCACLPSFYGWNCEHG 128
P + IC R + P G C CLNGG C+ C C P + G C
Sbjct: 3475 PCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTA 3534
Query: 129 VRKENCGSVPHDTRLPKKCSMCKCWHG 155
V + C + R P +C W G
Sbjct: 3535 VCQSPCLNGGKCVR-PNRCHCLSSWTG 3560
Score = 34.3 bits (77), Expect = 0.069
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 6/60 (10%)
Query: 79 CPRSSQLVPPMGIQDSKEPNRTC---CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG 135
C Q P G S+ C CLNGG C+ + C CL S+ G NC RK G
Sbjct: 3514 CVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCS---RKRRTG 3570
Score = 30.4 bits (67), Expect = 1.00
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 11/93 (11%)
Query: 92 QDSKEPNRTCCLNGGTCM---LGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCS 148
++ E + + CLN G C+ G C C+ F G +CE V + C S P +
Sbjct: 1268 ENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNE--CQSNPCLNN-----A 1320
Query: 149 MCKCWHGQLRC-FPQAFLPGCDGLVMDEHLMAP 180
+C+ G C P FL G +DE L P
Sbjct: 1321 VCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP 1353
Score = 27.7 bits (60), Expect = 6.5
Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 21/101 (20%)
Query: 99 RTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLR 158
R+ CL GT C + F C++G + P CS + W G+L
Sbjct: 3453 RSVCLENGTWTSPPICRAVCRF---PCQNGGICQR----------PNACSCPEGWMGRLC 3499
Query: 159 CFPQAFLPGCDGLVMDEHLMAPRTPELPP----SACTTFIC 195
P LP +G +AP + PP S C T +C
Sbjct: 3500 EEPICILPCLNG----GRCVAPYQCDCPPGWTGSRCHTAVC 3536
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 37.0 bits (84), Expect = 0.011
Identities = 16/30 (53%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 99 RTCCLNGGTCMLGSFCACLPSFYGWNCEHG 128
R CL+GGTC G+ C CLP F G C+ G
Sbjct: 4150 REPCLHGGTCQ-GTRCLCLPGFSGPRCQQG 4178
Score = 28.1 bits (61), Expect = 4.9
Identities = 22/69 (31%), Positives = 25/69 (36%), Gaps = 11/69 (15%)
Query: 102 CLNGGTC----MLGSFCACLPSFYGWNCEHG----VRKENCGSVPHDTRLPK-KCSMCKC 152
C NGG C C C F G CEH E CG P + C+C
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRGYTCRC 3912
Query: 153 WHGQ--LRC 159
G+ LRC
Sbjct: 3913 HLGRSGLRC 3921
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 36.6 bits (83), Expect = 0.014
Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 1/54 (1%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHG 155
C +GGTC+ G+ C C F G CE V +C + P C W+G
Sbjct: 1366 CQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCEN-GGQCLTPDICQCKPGWYG 1418
Score = 35.8 bits (81), Expect = 0.024
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 13/100 (13%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQL-RCF 160
CLNGG+C + C C F+G +C++ C + H R ++C C G R F
Sbjct: 1430 CLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMR----NNVCVCREGYTGRRF 1485
Query: 161 PQAFLPGCDGLVMD-EHLMAPRTPELPP----SACTTFIC 195
++ CD M+ + P T P C T IC
Sbjct: 1486 QKSI---CDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPIC 1522
Score = 33.9 bits (76), Expect = 0.090
Identities = 22/87 (25%), Positives = 31/87 (35%), Gaps = 7/87 (8%)
Query: 72 PQEEPAICPRSSQLVPPMGIQDSKEPNRTC---CLNGGTCMLGSFCACLPSFYGWNCEHG 128
P + C + P G + C C NGG C+ C C P +YG C
Sbjct: 1365 PCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTA 1424
Query: 129 VRKENCGSVPHDTRLPKKCSMCKCWHG 155
+ C V + K + C C +G
Sbjct: 1425 L----CDPVCLNGGSCNKPNTCLCPNG 1447
Score = 33.1 bits (74), Expect = 0.15
Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 12/46 (26%)
Query: 102 CLNGGTCML------GS---FCACLPSFYGWNCE---HGVRKENCG 135
CLNGG+C+ GS C CLP F+G CE G + CG
Sbjct: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCG 1228
Score = 33.1 bits (74), Expect = 0.15
Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 23/105 (21%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFP 161
C N G C+ + C CLP G C+ +E+C P C G L P
Sbjct: 1334 CKNHGKCIKPNICQCLPGHGGATCD----EEHCN--------PPCQHGGTCLAGNLCTCP 1381
Query: 162 QAFL-PGCDGLVMDEH------LMAPRTPELPPS----ACTTFIC 195
F+ P C+ +V + H + P + P C+T +C
Sbjct: 1382 YGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALC 1426
Score = 33.1 bits (74), Expect = 0.15
Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 5/93 (5%)
Query: 79 CPRSSQLVPPMGIQDSKEPNRTC---CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG 135
C R++ V G + C C+NGG C+ S C+C + G C + + C
Sbjct: 1468 CMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCK 1527
Query: 136 SVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGC 168
+ + P C W G +RC P C
Sbjct: 1528 N-GGECIAPSICHCPSSWEG-VRCQIPICNPKC 1558
Score = 32.0 bits (71), Expect = 0.34
Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 2/67 (2%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFP 161
C C+ + C C P + G NC+ + +C + H + C HG C
Sbjct: 1302 CGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKN--HGKCIKPNICQCLPGHGGATCDE 1359
Query: 162 QAFLPGC 168
+ P C
Sbjct: 1360 EHCNPPC 1366
Score = 29.6 bits (65), Expect = 1.7
Identities = 10/29 (34%), Positives = 16/29 (55%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVR 130
CL GG C+ + C+C + G CE ++
Sbjct: 1558 CLYGGRCIFPNVCSCRTEYSGVKCEKKIQ 1586
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 36.2 bits (82), Expect = 0.018
Identities = 16/36 (44%), Positives = 19/36 (52%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSV 137
CLNGG C+ + CAC F G CE R C +V
Sbjct: 154 CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTV 189
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 36.2 bits (82), Expect = 0.018
Identities = 31/122 (25%), Positives = 39/122 (31%), Gaps = 32/122 (26%)
Query: 102 CLNGGTCML------GSFCACLPSFYGWNCEHGVRKENCGS--------------VPHDT 141
CLNGGTC + G C C P F G C+ + C P
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 142 RLPKKCSMCKCWHGQLRCFPQ--------AFLPGCDGLVMDEHLMAPRTPELPPSACTTF 193
C+ C HG C PQ P G + + P T PP+ C +
Sbjct: 1373 DCESGCASSPCQHGG-SCHPQRQPPYYSCQCAPPFSGSRCELYTAPPST---PPATCLSQ 1428
Query: 194 IC 195
C
Sbjct: 1429 YC 1430
Score = 35.4 bits (80), Expect = 0.031
Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 3/33 (9%)
Query: 102 CLNGGTCM--LGSF-CACLPSFYGWNCEHGVRK 131
CLNGG CM +G + C CLP F G CE + +
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINE 1267
Score = 34.7 bits (78), Expect = 0.053
Identities = 16/32 (50%), Positives = 18/32 (56%), Gaps = 4/32 (12%)
Query: 102 CLNGGTC-MLGSF---CACLPSFYGWNCEHGV 129
C+NGGTC G F C CLP F G CE +
Sbjct: 230 CVNGGTCRQTGDFTFECNCLPGFEGSTCERNI 261
Score = 33.9 bits (76), Expect = 0.090
Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 93 DSKEPNRTCCLNGGTC---MLGSFCACLPSFYGWNCEHGVRKENCGSVP 138
D E C NGGTC + G C C F G+NC+ V + C S P
Sbjct: 757 DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ--VNIDECASNP 803
Score = 31.6 bits (70), Expect = 0.45
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 13/79 (16%)
Query: 102 CLNGGTCMLGS---FCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLR 158
C NGG+CM G C CLP F G C+ + + C S P K C +
Sbjct: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE--CLSEP-----CKNGGTCSDYVNSYT 972
Query: 159 CFPQAFLPGCDGLVMDEHL 177
C QA G DG+ + ++
Sbjct: 973 CKCQA---GFDGVHCENNI 988
Score = 31.6 bits (70), Expect = 0.45
Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 5/40 (12%)
Query: 102 CLNGGTC--MLGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
C +G TC +G + C C+P + G NCE+ V + C + P
Sbjct: 1158 CQHGATCSDFIGGYRCECVPGYQGVNCEYEV--DECQNQP 1195
Score = 30.8 bits (68), Expect = 0.76
Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
Query: 93 DSKEPNRTCCLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
D E + C N TC+ +G F C C+P F G +CE + + C S P
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINE--CQSNP 502
Score = 30.4 bits (67), Expect = 1.00
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 5/46 (10%)
Query: 96 EPNRTCCLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
E + C NGGTC+ + SF C C F G C H + + C S P
Sbjct: 990 ECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINE--CSSHP 1033
Score = 29.3 bits (64), Expect = 2.2
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 102 CLNGGTCM---LGSFCACLPSFYGWNCEHGVRKENCGSVP 138
CLN G C+ G C C P G NCE + ++C S P
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCE--INFDDCASNP 653
Score = 28.1 bits (61), Expect = 4.9
Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 7/60 (11%)
Query: 102 CLNGGTCMLGS----FCACLPSFYGWNCE--HGVRKENCGSVPHDTRLPKKCSMCKCWHG 155
CLNGGTC + S C C F G C+ C + T + + S CKC G
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFS-CKCLTG 173
Score = 28.1 bits (61), Expect = 4.9
Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Query: 102 CLNGGTC--MLGSF-CACLPSFYGWNCEHGV 129
C+N G C GS+ C C P F G +CE +
Sbjct: 882 CMNHGLCHNTQGSYMCECPPGFSGMDCEEDI 912
Score = 27.3 bits (59), Expect = 8.4
Identities = 14/33 (42%), Positives = 16/33 (48%), Gaps = 3/33 (9%)
Query: 102 CLNGGTC--MLGSF-CACLPSFYGWNCEHGVRK 131
C NG TC + F C CL F G CE V +
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 185
>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
[Homo sapiens]
Length = 909
Score = 36.2 bits (82), Expect = 0.018
Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Query: 81 RSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG 135
R++++ M Q + C NGGT G CACLP F G C+ R +N G
Sbjct: 826 RTTRITSQMTTQSTLTTTAGTCDNGGTWEQGQ-CACLPGFSGDRCQLQTRCQNGG 879
Score = 29.3 bits (64), Expect = 2.2
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 99 RTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG 135
+T C NGG G C C +FYG +CE V + + G
Sbjct: 872 QTRCQNGGQWD-GLKCQCPSTFYGSSCEFAVEQVDLG 907
>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
Length = 1486
Score = 36.2 bits (82), Expect = 0.018
Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Query: 81 RSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG 135
R++++ M Q + C NGGT G CACLP F G C+ R +N G
Sbjct: 1100 RTTRITSQMTTQSTLTTTAGTCDNGGTWEQGQ-CACLPGFSGDRCQLQTRCQNGG 1153
Score = 27.7 bits (60), Expect = 6.5
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 99 RTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRK 131
+T C NGG G C C +FYG +CE V +
Sbjct: 1146 QTRCQNGGQWD-GLKCQCPSTFYGSSCEFAVEQ 1177
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 36.2 bits (82), Expect = 0.018
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
C NGG C+ + CAC F G +CE + + + G V D+R
Sbjct: 552 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSR 592
Score = 30.8 bits (68), Expect = 0.76
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 14/78 (17%)
Query: 93 DSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC-------GSVPHDTRL-- 143
+S E C +C + C L Y C HG +NC G V H+ ++
Sbjct: 621 ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG---KNCTGDCIHDGKVKHNGQIWV 677
Query: 144 --PKKCSMCKCWHGQLRC 159
+CS+C C +G + C
Sbjct: 678 LENDRCSVCSCQNGFVMC 695
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 36.2 bits (82), Expect = 0.018
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
C NGG C+ + CAC F G +CE + + + G V D+R
Sbjct: 528 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSR 568
Score = 30.8 bits (68), Expect = 0.76
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 14/78 (17%)
Query: 93 DSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC-------GSVPHDTRL-- 143
+S E C +C + C L Y C HG +NC G V H+ ++
Sbjct: 597 ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG---KNCTGDCIHDGKVKHNGQIWV 653
Query: 144 --PKKCSMCKCWHGQLRC 159
+CS+C C +G + C
Sbjct: 654 LENDRCSVCSCQNGFVMC 671
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 36.2 bits (82), Expect = 0.018
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
C NGG C+ + CAC F G +CE + + + G V D+R
Sbjct: 529 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSR 569
Score = 30.8 bits (68), Expect = 0.76
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 14/78 (17%)
Query: 93 DSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC-------GSVPHDTRL-- 143
+S E C +C + C L Y C HG +NC G V H+ ++
Sbjct: 598 ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG---KNCTGDCIHDGKVKHNGQIWV 654
Query: 144 --PKKCSMCKCWHGQLRC 159
+CS+C C +G + C
Sbjct: 655 LENDRCSVCSCQNGFVMC 672
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 36.2 bits (82), Expect = 0.018
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
C NGG C+ + CAC F G +CE + + + G V D+R
Sbjct: 579 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSR 619
Score = 30.8 bits (68), Expect = 0.76
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 14/78 (17%)
Query: 93 DSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC-------GSVPHDTRL-- 143
+S E C +C + C L Y C HG +NC G V H+ ++
Sbjct: 648 ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG---KNCTGDCIHDGKVKHNGQIWV 704
Query: 144 --PKKCSMCKCWHGQLRC 159
+CS+C C +G + C
Sbjct: 705 LENDRCSVCSCQNGFVMC 722
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 36.2 bits (82), Expect = 0.018
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
C NGG C+ + CAC F G +CE + + + G V D+R
Sbjct: 529 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSR 569
Score = 30.8 bits (68), Expect = 0.76
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 14/78 (17%)
Query: 93 DSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC-------GSVPHDTRL-- 143
+S E C +C + C L Y C HG +NC G V H+ ++
Sbjct: 598 ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG---KNCTGDCIHDGKVKHNGQIWV 654
Query: 144 --PKKCSMCKCWHGQLRC 159
+CS+C C +G + C
Sbjct: 655 LENDRCSVCSCQNGFVMC 672
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 36.2 bits (82), Expect = 0.018
Identities = 19/40 (47%), Positives = 23/40 (57%), Gaps = 5/40 (12%)
Query: 102 CLNGGTCM--LGS-FCACLPSFYGWNCEHGVRKENCGSVP 138
CLNG TC LG+ FC C P F G +CE + + C S P
Sbjct: 233 CLNGATCQDALGAYFCDCAPGFLGDHCE--LNTDECASQP 270
Score = 27.7 bits (60), Expect = 6.5
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 93 DSKEPNRTCCLNGGTC---MLGSFCACLPSFYGWNCEHGVRKENCGSVP 138
D E + C NG C + G C C+P + G +C+ + + C S P
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCD--LEVDECASDP 194
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 35.4 bits (80), Expect = 0.031
Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 11/67 (16%)
Query: 102 CLNGGTCML---GSFCACLPSFYGWNCEHGVRKENCGSVP---HDTRLPKKCSM-CKCWH 154
C NG TCM G C C P + G NC + + C S P H T PK C C
Sbjct: 939 CQNGATCMAQPSGYLCQCAPGYDGQNCSKEL--DACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 155 G--QLRC 159
G LRC
Sbjct: 997 GFVGLRC 1003
Score = 32.7 bits (73), Expect = 0.20
Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 24/85 (28%)
Query: 74 EEPAICPR---------SSQLVPPMGIQDSKEPNRT--C----CLNGGTCML-------G 111
++P CP+ S Q + P+G + + R C C NGGTC L
Sbjct: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF 259
Query: 112 SFCACLPSFYGWNCEHGVRKENCGS 136
C C P F G +CE V +NC S
Sbjct: 260 HLCLCPPGFIGPDCE--VNPDNCVS 282
Score = 32.0 bits (71), Expect = 0.34
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 3/41 (7%)
Query: 102 CLNGGTCMLGS---FCACLPSFYGWNCEHGVRKENCGSVPH 139
C NGGTC G C C ++ GW+C V + PH
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPH 325
Score = 32.0 bits (71), Expect = 0.34
Identities = 32/102 (31%), Positives = 35/102 (34%), Gaps = 29/102 (28%)
Query: 102 CLNGGTCM------LGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHG 155
C +GGTC LG C C F G C H R P C C HG
Sbjct: 1055 CFHGGTCEATAGSPLGFICHCPKGFEGPTCSH--------------RAP-SCGFHHCHHG 1099
Query: 156 QLRCFPQ---AFLPGCDGL--VMDEHLMAPRTPE--LPPSAC 190
L C P F P C L + P P+ PPS C
Sbjct: 1100 GL-CLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC 1140
Score = 31.6 bits (70), Expect = 0.45
Identities = 36/127 (28%), Positives = 45/127 (35%), Gaps = 38/127 (29%)
Query: 85 LVPPMGIQDSKEPNRTCCLNGGTCMLGSF----CACLPSFYGWN------CEHGVRKENC 134
+V P G+ P C NGGTC+ S C C P F G C++ +N
Sbjct: 20 VVRPRGLLCGSFPEP--CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNG 77
Query: 135 GS----VPHDTRLPKKCS------MCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAPRTPE 184
GS +P LP S +C C LPG G E A
Sbjct: 78 GSCQALLPAPLGLPSSPSPLTPSFLCTC------------LPGFTG----ERCQAKLEDP 121
Query: 185 LPPSACT 191
PPS C+
Sbjct: 122 CPPSFCS 128
Score = 31.6 bits (70), Expect = 0.45
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 5/50 (10%)
Query: 92 QDSKEPNRTCCLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
+D E + C NGG C G+F C CLP F G C+ V + C S P
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV--DECLSDP 597
Score = 31.2 bits (69), Expect = 0.58
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 102 CLNGGTC--MLGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
CLN C +L F C CLP F G CE + + C S P
Sbjct: 522 CLNHADCHDLLNGFQCICLPGFSGTRCEEDI--DECRSSP 559
Score = 30.8 bits (68), Expect = 0.76
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 102 CLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
C NGGTC+ G+F C C F G CE G + +C P
Sbjct: 776 CFNGGTCVNRPGTFSCLCAMGFQGPRCE-GKLRPSCADSP 814
Score = 30.4 bits (67), Expect = 1.00
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 102 CLNGGTCML---GSFCACLPSFYGWNCEHGVRKENCGSVP 138
CLNGG+C G +C C PS G C+ + C S P
Sbjct: 738 CLNGGSCNPSPGGYYCTCPPSHTGPQCQ--TSTDYCVSAP 775
Score = 30.4 bits (67), Expect = 1.00
Identities = 23/64 (35%), Positives = 27/64 (42%), Gaps = 8/64 (12%)
Query: 102 CLNGGTCML---GSFCACLPSFYGWNCEHGVRKENCGSVP-HDTRLPKKCSMCKCWHGQL 157
C N GTC G CAC P F G CE V + C P H T S+ ++ Q
Sbjct: 977 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDV--DECLDQPCHPTGTAACHSLANAFYCQ- 1033
Query: 158 RCFP 161
C P
Sbjct: 1034 -CLP 1036
Score = 29.3 bits (64), Expect = 2.2
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 7/57 (12%)
Query: 102 CLNGGTCMLGSF----CACLPSFYGWNCEHGVRK--ENCGSVPHDTRLPKKCSMCKC 152
C+NGG C L ++ C C P F G CE V + ++ G P T +C
Sbjct: 165 CVNGGVC-LATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220
Score = 27.3 bits (59), Expect = 8.4
Identities = 16/40 (40%), Positives = 18/40 (45%), Gaps = 5/40 (12%)
Query: 102 CLNGGTCMLGS---FCACLPSFYGWNCEHGVRKENCGSVP 138
C NGG C+ FC C P F G C+ V C S P
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNP--CESRP 938
>gi|126012562 low density lipoprotein-related protein 1 [Homo sapiens]
Length = 4544
Score = 35.0 bits (79), Expect = 0.040
Identities = 28/98 (28%), Positives = 37/98 (37%), Gaps = 16/98 (16%)
Query: 70 IQPQEEPAICPRSSQL-------VP-PMGIQDSKEPNRTC---CLNGGTCMLGSF----C 114
+ P CP +L VP P D+ P TC C NGG+C L + C
Sbjct: 4162 LSPSGPVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPG-TCNLQCFNGGSCFLNARRQPKC 4220
Query: 115 ACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKC 152
C P + G CE E+C + P C+C
Sbjct: 4221 RCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRC 4258
Score = 28.9 bits (63), Expect = 2.9
Identities = 15/47 (31%), Positives = 19/47 (40%), Gaps = 7/47 (14%)
Query: 88 PMGIQDSKEPNRTC---CLNGGTCMLGSF----CACLPSFYGWNCEH 127
P G K + C C N TC + C CLP F G C++
Sbjct: 4259 PTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQY 4305
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.467
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,435,509
Number of Sequences: 37866
Number of extensions: 464293
Number of successful extensions: 1647
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 95
Number of HSP's that attempted gapping in prelim test: 1264
Number of HSP's gapped (non-prelim): 445
length of query: 195
length of database: 18,247,518
effective HSP length: 97
effective length of query: 98
effective length of database: 14,574,516
effective search space: 1428302568
effective search space used: 1428302568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.