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Search of human proteins with 16876441
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16876441 dachshund 2 isoform a [Homo sapiens]
(599 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16876441 dachshund 2 isoform a [Homo sapiens] 1185 0.0
gi|213972566 dachshund 2 isoform b [Homo sapiens] 1117 0.0
gi|213972568 dachshund 2 isoform c [Homo sapiens] 849 0.0
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 561 e-160
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 256 5e-68
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 220 3e-57
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 61 3e-09
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 61 3e-09
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 61 3e-09
gi|73476377 LBXCOR1 homolog [Homo sapiens] 57 6e-08
gi|148762982 hypothetical protein LOC387640 [Homo sapiens] 56 1e-07
gi|56549694 enabled homolog isoform a [Homo sapiens] 52 2e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 52 2e-06
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 51 3e-06
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 51 3e-06
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 51 3e-06
gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens] 50 6e-06
gi|223029422 SKI-like isoform 3 [Homo sapiens] 49 1e-05
gi|223029418 SKI-like isoform 1 [Homo sapiens] 49 1e-05
gi|148746195 trichohyalin [Homo sapiens] 48 2e-05
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 47 5e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 47 7e-05
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 47 7e-05
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 47 7e-05
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 47 7e-05
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 47 7e-05
gi|223029420 SKI-like isoform 2 [Homo sapiens] 46 9e-05
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 45 1e-04
gi|67763814 death-inducing-protein [Homo sapiens] 44 4e-04
gi|62244004 modulator of estrogen induced transcription isoform ... 43 7e-04
>gi|16876441 dachshund 2 isoform a [Homo sapiens]
Length = 599
Score = 1185 bits (3065), Expect = 0.0
Identities = 599/599 (100%), Positives = 599/599 (100%)
Query: 1 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 60
MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR
Sbjct: 1 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 60
Query: 61 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 120
GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP
Sbjct: 61 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 120
Query: 121 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG 180
VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG
Sbjct: 121 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG 180
Query: 181 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 240
RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN
Sbjct: 181 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 240
Query: 241 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 300
GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN
Sbjct: 241 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 300
Query: 301 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 360
PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS
Sbjct: 301 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 360
Query: 361 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 420
RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI
Sbjct: 361 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 420
Query: 421 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 480
PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI
Sbjct: 421 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 480
Query: 481 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 540
QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR
Sbjct: 481 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 540
Query: 541 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA 599
EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA
Sbjct: 541 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA 599
>gi|213972566 dachshund 2 isoform b [Homo sapiens]
Length = 571
Score = 1117 bits (2889), Expect = 0.0
Identities = 570/583 (97%), Positives = 570/583 (97%), Gaps = 13/583 (2%)
Query: 1 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 60
MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR
Sbjct: 1 MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 60
Query: 61 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 120
GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP
Sbjct: 61 GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 120
Query: 121 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG 180
VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNA SSRPG
Sbjct: 121 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNA-------------SSRPG 167
Query: 181 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 240
RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN
Sbjct: 168 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 227
Query: 241 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 300
GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN
Sbjct: 228 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 287
Query: 301 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 360
PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS
Sbjct: 288 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 347
Query: 361 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 420
RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI
Sbjct: 348 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 407
Query: 421 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 480
PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI
Sbjct: 408 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 467
Query: 481 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 540
QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR
Sbjct: 468 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 527
Query: 541 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ 583
EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ
Sbjct: 528 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ 570
>gi|213972568 dachshund 2 isoform c [Homo sapiens]
Length = 432
Score = 849 bits (2193), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 168 MTRKQAVNSSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQ 227
MTRKQAVNSSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQ
Sbjct: 1 MTRKQAVNSSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQ 60
Query: 228 KMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAAL 287
KMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAAL
Sbjct: 61 KMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAAL 120
Query: 288 AGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIA 347
AGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIA
Sbjct: 121 AGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIA 180
Query: 348 NMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMD 407
NMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMD
Sbjct: 181 NMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMD 240
Query: 408 HHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLK 467
HHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLK
Sbjct: 241 HHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLK 300
Query: 468 VALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR 527
VALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR
Sbjct: 301 VALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR 360
Query: 528 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNY 587
KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNY
Sbjct: 361 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNY 420
Query: 588 YCLEMAQQLYSA 599
YCLEMAQQLYSA
Sbjct: 421 YCLEMAQQLYSA 432
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 561 bits (1445), Expect = e-160
Identities = 329/643 (51%), Positives = 399/643 (62%), Gaps = 149/643 (23%)
Query: 4 SASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGRGNT 63
S+S S++SS + G +P+YSTP P TP
Sbjct: 148 SSSSSSSSSSSSSSSSCGPLPGKPVYSTP-SPVENTPQ---------------------- 184
Query: 64 NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
NEC+MVD+ G KVASF ++G ELICLPQ FDLFLKHLVGGLHTVYTKLKRL+I+PVVC
Sbjct: 185 -NNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVC 243
Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPGRPP 183
VEQVRILRGLGAIQPGVNRCKLI+RKDFETL+ DCTNA SSRPGRPP
Sbjct: 244 NVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA-------------SSRPGRPP 290
Query: 184 KRSLGVLQ-ENARLLTHAVPGLLSPGLITPTGITAAA----------MAEAMKLQKMKLM 232
KR+ V EN+ ++ H+VPGL+SPG+I PTG+TAAA +AEAMK++K+KL
Sbjct: 291 KRTQSVTSPENSHIMPHSVPGLMSPGIIPPTGLTAAAAAAAAATNAAIAEAMKVKKIKLE 350
Query: 233 AMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPG 292
AM+ + +Q+G +SE D+NS+ G
Sbjct: 351 AMSNYHASNNQHGADSENGDMNSSVG---------------------------------- 376
Query: 293 IGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAA 352
L+LPFMMMPHPL+PVSLPPASV MAM+QMNHL+TIANMAAA
Sbjct: 377 -------------------LELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAA 417
Query: 353 AQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQ------- 405
AQ+ SP SR TSVIKER+P+SPSPAPSLEE RPGS SSH SSSVSSSP++
Sbjct: 418 AQVQSPPSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDR 477
Query: 406 ----------------------------------MDHHLERM----EEVPVQIPIMKSPL 427
M H +RM +E P+ P + L
Sbjct: 478 IPVHQNGLSMNQMLMGLSPNVLPGPKEGDLAGHDMGHESKRMHIEKDETPLSTPTARDSL 537
Query: 428 DKIQLTP-GQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKE 486
DK+ LT GQ LP GFP PF+F D LSS+ETLLTNIQGLLKVA+DNAR QEKQ+Q EK E
Sbjct: 538 DKLSLTGHGQPLPPGFPSPFLFPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTE 597
Query: 487 LRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQA 546
L+++ RERE+RE LE+QLA+E ++R +QKRLKKEKK KRKLQEALEFE+KRREQ EQ
Sbjct: 598 LKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQT 657
Query: 547 LKQATTSDSGLRMLKDTGIPDIEIENNGTPHDS-AAMQGGNYY 588
LKQA ++DS LR+L D+ P+IE + +G D+ +Q G Y
Sbjct: 658 LKQAASTDS-LRVLNDSLTPEIEADRSGGRTDAERTIQDGRLY 699
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 256 bits (653), Expect = 5e-68
Identities = 150/308 (48%), Positives = 190/308 (61%), Gaps = 61/308 (19%)
Query: 4 SASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGRGNT 63
S+S S++SS + G +P+YSTP P TP
Sbjct: 148 SSSSSSSSSSSSSSSSCGPLPGKPVYSTP-SPVENTPQ---------------------- 184
Query: 64 NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
NEC+MVD+ G KVASF ++G ELICLPQ FDLFLKHLVGGLHTVYTKLKRL+I+PVVC
Sbjct: 185 -NNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVC 243
Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPGRPP 183
VEQVRILRGLGAIQPGVNRCKLI+RKDFETL+ DCTNA SSRPGRPP
Sbjct: 244 NVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA-------------SSRPGRPP 290
Query: 184 KRSLGVLQ-ENARLLTHAVPGLLSPGLITPTGITA----------AAMAEAMKLQKMKLM 232
KR+ V EN+ ++ H+VPGL+SPG+I PTG+TA AA+AEAMK++K+KL
Sbjct: 291 KRTQSVTSPENSHIMPHSVPGLMSPGIIPPTGLTAAAAAAAAATNAAIAEAMKVKKIKLE 350
Query: 233 AMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALA--GQ 290
AM+ + +Q+G +SE D+NS+ ++P + P + + +L GQ
Sbjct: 351 AMSNYHASNNQHGADSENGDMNSSVD-----------ETPLSTPTARDSLDKLSLTGHGQ 399
Query: 291 PGIGGAPT 298
P G P+
Sbjct: 400 PLPPGFPS 407
Score = 205 bits (522), Expect = 8e-53
Identities = 110/202 (54%), Positives = 145/202 (71%), Gaps = 3/202 (1%)
Query: 389 SQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTP-GQALPAGFPGPFI 447
+ ++ H S++ + S+ ++E P+ P + LDK+ LT GQ LP GFP PF+
Sbjct: 351 AMSNYHASNNQHGADSENGDMNSSVDETPLSTPTARDSLDKLSLTGHGQPLPPGFPSPFL 410
Query: 448 FADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAV 507
F D LSS+ETLLTNIQGLLKVA+DNAR QEKQ+Q EK EL+++ RERE+RE LE+QLA+
Sbjct: 411 FPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAM 470
Query: 508 ELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPD 567
E ++R +QKRLKKEKK KRKLQEALEFE+KRREQ EQ LKQA ++DS LR+L D+ P+
Sbjct: 471 EQKNRAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDS-LRVLNDSLTPE 529
Query: 568 IEIENNGTPHDS-AAMQGGNYY 588
IE + +G D+ +Q G Y
Sbjct: 530 IEADRSGGRTDAERTIQDGRLY 551
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 220 bits (560), Expect = 3e-57
Identities = 125/230 (54%), Positives = 148/230 (64%), Gaps = 39/230 (16%)
Query: 4 SASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGRGNT 63
S+S S++SS + G +P+YSTP P TP
Sbjct: 148 SSSSSSSSSSSSSSSSCGPLPGKPVYSTP-SPVENTPQ---------------------- 184
Query: 64 NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
NEC+MVD+ G KVASF ++G ELICLPQ FDLFLKHLVGGLHTVYTKLKRL+I+PVVC
Sbjct: 185 -NNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVC 243
Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPGRPP 183
VEQVRILRGLGAIQPGVNRCKLI+RKDFETL+ DCTNA SSRPGRPP
Sbjct: 244 NVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA-------------SSRPGRPP 290
Query: 184 KRSLGVLQ-ENARLLTHAVPGLLSPGLITPTGITAAAMAEAM-KLQKMKL 231
KR+ V EN+ ++ H+VPGL+SPG+I PT T + A L K+ L
Sbjct: 291 KRTQSVTSPENSHIMPHSVPGLMSPGIIPPTDETPLSTPTARDSLDKLSL 340
Score = 203 bits (517), Expect = 3e-52
Identities = 117/211 (55%), Positives = 146/211 (69%), Gaps = 9/211 (4%)
Query: 386 RPGSQTSSHTSSSVS-----SSPSQMDHHL-ERMEEVPVQIPIMKSPLDKIQLTP-GQAL 438
RP +T S TS S S P M + +E P+ P + LDK+ LT GQ L
Sbjct: 288 RPPKRTQSVTSPENSHIMPHSVPGLMSPGIIPPTDETPLSTPTARDSLDKLSLTGHGQPL 347
Query: 439 PAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIR 498
P GFP PF+F D LSS+ETLLTNIQGLLKVA+DNAR QEKQ+Q EK EL+++ RERE+R
Sbjct: 348 PPGFPSPFLFPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELR 407
Query: 499 ENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLR 558
E LE+QLA+E ++R +QKRLKKEKK KRKLQEALEFE+KRREQ EQ LKQA ++DS LR
Sbjct: 408 ETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDS-LR 466
Query: 559 MLKDTGIPDIEIENNGTPHDS-AAMQGGNYY 588
+L D+ P+IE + +G D+ +Q G Y
Sbjct: 467 VLNDSLTPEIEADRSGGRTDAERTIQDGRLY 497
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 60.8 bits (146), Expect = 3e-09
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Query: 59 GRGNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDI 118
G N N+ V ++G+ + S ++DGQE +CL Q+ + LK+ + ++ + L I
Sbjct: 32 GHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNF--SYNEIHNRRVALGI 89
Query: 119 SPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETL 155
+ V CT Q+ ILR GA+ RC +IT+++ E L
Sbjct: 90 TCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERL 126
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 60.8 bits (146), Expect = 3e-09
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Query: 59 GRGNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDI 118
G N N+ V ++G+ + S ++DGQE +CL Q+ + LK+ + ++ + L I
Sbjct: 32 GHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNF--SYNEIHNRRVALGI 89
Query: 119 SPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETL 155
+ V CT Q+ ILR GA+ RC +IT+++ E L
Sbjct: 90 TCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERL 126
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 60.8 bits (146), Expect = 3e-09
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Query: 59 GRGNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDI 118
G N N+ V ++G+ + S ++DGQE +CL Q+ + LK+ + ++ + L I
Sbjct: 32 GHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNF--SYNEIHNRRVALGI 89
Query: 119 SPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETL 155
+ V CT Q+ ILR GA+ RC +IT+++ E L
Sbjct: 90 TCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERL 126
>gi|73476377 LBXCOR1 homolog [Homo sapiens]
Length = 921
Score = 56.6 bits (135), Expect = 6e-08
Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 2/119 (1%)
Query: 37 RLTPNMINSFVVNNHSNSAGGGGRGNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFD 96
+L P S N+ G N+ ++G+ + S ++DGQE +CL Q+ +
Sbjct: 37 QLGPGREGSSSPNSKQELQPYSGSSALKPNQVGETSLYGVPIVSLVIDGQERLCLAQISN 96
Query: 97 LFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETL 155
LK+ + ++ + L I+ V CT Q+ ILR GA+ RC +IT+++ E L
Sbjct: 97 TLLKNY--SYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERL 153
>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
Length = 908
Score = 55.8 bits (133), Expect = 1e-07
Identities = 30/115 (26%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Query: 72 DMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRIL 131
++ G+++ ++ G+++ L QVF LK++ TV+ ++ L + C +E++R L
Sbjct: 10 EVDGVRLGYLIIKGKQMFALSQVFTDLLKNIPRT--TVHKRMDHLKVKKHHCDLEELRKL 67
Query: 132 RGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPGRPPKRS 186
+ + +I +C LI+R+D E L+T C R + R+ + PP+R+
Sbjct: 68 KAINSIAFHAAKCTLISREDVEALYTSCKTERVLKTKRRRVGRALATKAPPPERA 122
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 52.0 bits (123), Expect = 2e-06
Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 5/118 (4%)
Query: 470 LDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEK--KTKR 527
L+ R++ ++++QE+ E + ERE +E LERQ +E Q R Q+RL +E+ + +R
Sbjct: 176 LERERLERERLEQEQLERERQ---ERERQERLERQERLERQERLERQERLDRERQERQER 232
Query: 528 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGG 585
+ E LE E + RE+ EQ ++ + R+ +E N DS+A + G
Sbjct: 233 ERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG 290
Score = 36.6 bits (83), Expect = 0.068
Identities = 32/128 (25%), Positives = 65/128 (50%), Gaps = 16/128 (12%)
Query: 470 LDNARIQEKQIQQEKKEL----------RLELYREREIRENLERQLAVELQSRTTMQKRL 519
L+ R++++Q+++E++E RLE E +E L+R+ E Q R ++ RL
Sbjct: 181 LERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRE-RQERQERERLE-RL 238
Query: 520 KKEKKTKRKLQEALE---FESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTP 576
++E++ +R+ QE LE E +R ++ A A+ +L D+ + ++ P
Sbjct: 239 ERERQ-ERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQP 297
Query: 577 HDSAAMQG 584
++ + QG
Sbjct: 298 AETPSQQG 305
Score = 32.0 bits (71), Expect = 1.7
Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
Query: 479 QIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK-RLKKEKKTKRKL------QE 531
Q+Q + LE+ R + + +++L E R M++ RL++E+ + +L QE
Sbjct: 130 QVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQE 189
Query: 532 ALEFESKRREQVEQALKQ 549
LE E + RE+ E+ +Q
Sbjct: 190 QLERERQERERQERLERQ 207
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 52.0 bits (123), Expect = 2e-06
Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 5/118 (4%)
Query: 470 LDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEK--KTKR 527
L+ R++ ++++QE+ E + ERE +E LERQ +E Q R Q+RL +E+ + +R
Sbjct: 176 LERERLERERLEQEQLERERQ---ERERQERLERQERLERQERLERQERLDRERQERQER 232
Query: 528 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGG 585
+ E LE E + RE+ EQ ++ + R+ +E N DS+A + G
Sbjct: 233 ERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG 290
Score = 36.6 bits (83), Expect = 0.068
Identities = 32/128 (25%), Positives = 65/128 (50%), Gaps = 16/128 (12%)
Query: 470 LDNARIQEKQIQQEKKEL----------RLELYREREIRENLERQLAVELQSRTTMQKRL 519
L+ R++++Q+++E++E RLE E +E L+R+ E Q R ++ RL
Sbjct: 181 LERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRE-RQERQERERLE-RL 238
Query: 520 KKEKKTKRKLQEALE---FESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTP 576
++E++ +R+ QE LE E +R ++ A A+ +L D+ + ++ P
Sbjct: 239 ERERQ-ERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQP 297
Query: 577 HDSAAMQG 584
++ + QG
Sbjct: 298 AETPSQQG 305
Score = 32.0 bits (71), Expect = 1.7
Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
Query: 479 QIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK-RLKKEKKTKRKL------QE 531
Q+Q + LE+ R + + +++L E R M++ RL++E+ + +L QE
Sbjct: 130 QVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQE 189
Query: 532 ALEFESKRREQVEQALKQ 549
LE E + RE+ E+ +Q
Sbjct: 190 QLERERQERERQERLERQ 207
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 50.8 bits (120), Expect = 3e-06
Identities = 65/314 (20%), Positives = 131/314 (41%), Gaps = 63/314 (20%)
Query: 301 PLQQNHLLTNRLDLPFMMMPH--PLLPVS-LPPASVAM------------AMNQMNHLNT 345
P +QN ++ LD + + P P + PPAS+ + M +N
Sbjct: 321 PRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDENIELISGQNERMGPLNISTP 380
Query: 346 IANMAAAAQIHSPLSRAGTSVIK-ERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPS 404
+ +AA+ SP+ + S+ +I + PA L E HR S++++H S S
Sbjct: 381 VEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQS--- 437
Query: 405 QMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQG 464
G+ +P P +F+ +L + I
Sbjct: 438 ------------------------------GKVIPDRSTKPVVFSPTLMLTDEEKARIHA 467
Query: 465 LLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKE-- 522
+ ++ + QEK++++ ++E + E R+ E + +++ E T Q++ K+E
Sbjct: 468 ETALLMEKNK-QEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEME 526
Query: 523 -KKTKRKLQEALEFESKRREQV----EQALKQATTSDSGLRMLKDTG----IPDIEIENN 573
K++++ +E E +KR +++ Q+ + TSD+ + ++D G P+I+ ++
Sbjct: 527 KKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDA-KKSVEDRGKRCPTPEIQKKST 585
Query: 574 G-TPHDSAAMQGGN 586
G PH S G+
Sbjct: 586 GDVPHTSVTGDSGS 599
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 50.8 bits (120), Expect = 3e-06
Identities = 65/314 (20%), Positives = 131/314 (41%), Gaps = 63/314 (20%)
Query: 301 PLQQNHLLTNRLDLPFMMMPH--PLLPVS-LPPASVAM------------AMNQMNHLNT 345
P +QN ++ LD + + P P + PPAS+ + M +N
Sbjct: 321 PRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDENIELISGQNERMGPLNISTP 380
Query: 346 IANMAAAAQIHSPLSRAGTSVIK-ERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPS 404
+ +AA+ SP+ + S+ +I + PA L E HR S++++H S S
Sbjct: 381 VEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQS--- 437
Query: 405 QMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQG 464
G+ +P P +F+ +L + I
Sbjct: 438 ------------------------------GKVIPDRSTKPVVFSPTLMLTDEEKARIHA 467
Query: 465 LLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKE-- 522
+ ++ + QEK++++ ++E + E R+ E + +++ E T Q++ K+E
Sbjct: 468 ETALLMEKNK-QEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEME 526
Query: 523 -KKTKRKLQEALEFESKRREQV----EQALKQATTSDSGLRMLKDTG----IPDIEIENN 573
K++++ +E E +KR +++ Q+ + TSD+ + ++D G P+I+ ++
Sbjct: 527 KKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDA-KKSVEDRGKRCPTPEIQKKST 585
Query: 574 G-TPHDSAAMQGGN 586
G PH S G+
Sbjct: 586 GDVPHTSVTGDSGS 599
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 50.8 bits (120), Expect = 3e-06
Identities = 65/314 (20%), Positives = 131/314 (41%), Gaps = 63/314 (20%)
Query: 301 PLQQNHLLTNRLDLPFMMMPH--PLLPVS-LPPASVAM------------AMNQMNHLNT 345
P +QN ++ LD + + P P + PPAS+ + M +N
Sbjct: 321 PRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDENIELISGQNERMGPLNISTP 380
Query: 346 IANMAAAAQIHSPLSRAGTSVIK-ERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPS 404
+ +AA+ SP+ + S+ +I + PA L E HR S++++H S S
Sbjct: 381 VEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQS--- 437
Query: 405 QMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQG 464
G+ +P P +F+ +L + I
Sbjct: 438 ------------------------------GKVIPDRSTKPVVFSPTLMLTDEEKARIHA 467
Query: 465 LLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKE-- 522
+ ++ + QEK++++ ++E + E R+ E + +++ E T Q++ K+E
Sbjct: 468 ETALLMEKNK-QEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEME 526
Query: 523 -KKTKRKLQEALEFESKRREQV----EQALKQATTSDSGLRMLKDTG----IPDIEIENN 573
K++++ +E E +KR +++ Q+ + TSD+ + ++D G P+I+ ++
Sbjct: 527 KKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDA-KKSVEDRGKRCPTPEIQKKST 585
Query: 574 G-TPHDSAAMQGGN 586
G PH S G+
Sbjct: 586 GDVPHTSVTGDSGS 599
>gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]
Length = 728
Score = 50.1 bits (118), Expect = 6e-06
Identities = 62/255 (24%), Positives = 111/255 (43%), Gaps = 31/255 (12%)
Query: 346 IANMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGS-QTSSHTSSSVSSSPS 404
+A A + SP A S E + P PG+ +T + ++ S
Sbjct: 421 LAPPAQQKVVSSPPCAAAVSRAPEPLATCTQPRKRKLTVDTPGAPETLAPVAAPEEDKDS 480
Query: 405 QMDHHLERMEEVPVQIPIMKSPL------DKIQLTPG-QALPAGFPGPFIFADSLSSVET 457
+ + +E EE + + SP K +PG +ALP+ P AD+ S +E
Sbjct: 481 EAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLGSPGARALPSAVPDAAAPADAPSGLEA 540
Query: 458 LLTNIQGLLKVALDNARIQEK--------QIQQEKKELRLELYREREIRENLERQLAV-- 507
L +++ L+ LD +EK +++QE+K L L +R + + LE
Sbjct: 541 ELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEK-LSAALQAKRSLHQELEFLRVAKK 599
Query: 508 -ELQSRTTMQKRLKKE-----KKTKRKLQEALEFESKRREQVEQALKQATTSDSG----- 556
+L+ T ++ L+KE + ++K++EA E + + ++EQA +QA D G
Sbjct: 600 EKLREATEAKRNLRKEIERLRAENEKKMKEANESRLRLKRELEQA-RQARVCDKGCEAGR 658
Query: 557 LRMLKDTGIPDIEIE 571
LR I D++++
Sbjct: 659 LRAKYSAQIEDLQVK 673
Score = 46.2 bits (108), Expect = 9e-05
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 3/92 (3%)
Query: 64 NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
+T C V + G ++ F++ G++ +CLPQ+ + L+ L + L I C
Sbjct: 97 STERCETV-LEGETISCFVVGGEKRLCLPQILNSVLRDF--SLQQINAVCDELHIYCSRC 153
Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETL 155
T +Q+ IL+ +G + C LIT+ D E L
Sbjct: 154 TADQLEILKVMGILPFSAPSCGLITKTDAERL 185
Score = 31.6 bits (70), Expect = 2.2
Identities = 14/43 (32%), Positives = 31/43 (72%), Gaps = 1/43 (2%)
Query: 470 LDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSR 512
+++ +++ + + ++++LR +L RERE RE+LE+ + ELQ +
Sbjct: 667 IEDLQVKLQHAEADREQLRADLLREREAREHLEK-VVKELQEQ 708
>gi|223029422 SKI-like isoform 3 [Homo sapiens]
Length = 664
Score = 49.3 bits (116), Expect = 1e-05
Identities = 103/536 (19%), Positives = 193/536 (36%), Gaps = 86/536 (16%)
Query: 64 NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
++ E + G ++ F + G++ +CLPQV + L+ L + T L I C
Sbjct: 120 SSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFT--LQQINTVCDELYIYCSRC 177
Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPGRPP 183
T +Q+ IL+ LG + C LIT D + L C R R + +V ++
Sbjct: 178 TSDQLHILKVLGILPFNAPSCGLITLTDAQRL---CNALLRPRTFPQNGSVLPAKSSLAQ 234
Query: 184 KRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGNGSQ 243
+ G E GL +P E + + M++
Sbjct: 235 LKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHS------- 287
Query: 244 NGTESEPDDLNSNTGGSESSWD---------------------KDKMQSPFAA-PGPQHG 281
PD + G + W ++M+ F+ G ++
Sbjct: 288 ---HRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGKRNQ 344
Query: 282 IAHAALAGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMN 341
A +G P + + +H+ L + V P S+ A++Q
Sbjct: 345 SKTDAPSGMELQSWYPVIKQ-EGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVSQSK 403
Query: 342 HLNTIANMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSS 401
L A+ I +A +S ++ P SLEE + +TS S + +
Sbjct: 404 ELT---KTEASKSISRQSEKAHSSGKLQKTVSYPDV--SLEEQEKMDLKTSRELCSRLDA 458
Query: 402 SPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTN 461
S S + E + ++K+ G L A P + D +
Sbjct: 459 SISNNSTSKRKSESATCNLV---RDINKV----GIGLVAAASSPLLVKDVICED------ 505
Query: 462 IQGLLKVALDNARIQEKQIQ---QEKKELRLELYREREIRENLERQLAVELQSRTTMQKR 518
D +I E+ ++ +++++L L L +++++ Q+ V++ S + K
Sbjct: 506 ---------DKGKIMEEVMRTYLKQQEKLNLILQKKQQL------QMEVKMLSSSKSMKE 550
Query: 519 LKKEKKTKRKLQEALEFESKRR------------EQVEQALKQATTSDSGLRMLKD 562
L +E++ +K E+L+ E +R +++EQ +KQ T DS L K+
Sbjct: 551 LTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE 606
>gi|223029418 SKI-like isoform 1 [Homo sapiens]
Length = 684
Score = 49.3 bits (116), Expect = 1e-05
Identities = 103/536 (19%), Positives = 193/536 (36%), Gaps = 86/536 (16%)
Query: 64 NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
++ E + G ++ F + G++ +CLPQV + L+ L + T L I C
Sbjct: 140 SSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFT--LQQINTVCDELYIYCSRC 197
Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPGRPP 183
T +Q+ IL+ LG + C LIT D + L C R R + +V ++
Sbjct: 198 TSDQLHILKVLGILPFNAPSCGLITLTDAQRL---CNALLRPRTFPQNGSVLPAKSSLAQ 254
Query: 184 KRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGNGSQ 243
+ G E GL +P E + + M++
Sbjct: 255 LKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHS------- 307
Query: 244 NGTESEPDDLNSNTGGSESSWD---------------------KDKMQSPFAA-PGPQHG 281
PD + G + W ++M+ F+ G ++
Sbjct: 308 ---HRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSGKRNQ 364
Query: 282 IAHAALAGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMN 341
A +G P + + +H+ L + V P S+ A++Q
Sbjct: 365 SKTDAPSGMELQSWYPVIKQ-EGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVSQSK 423
Query: 342 HLNTIANMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSS 401
L A+ I +A +S ++ P SLEE + +TS S + +
Sbjct: 424 ELT---KTEASKSISRQSEKAHSSGKLQKTVSYPDV--SLEEQEKMDLKTSRELCSRLDA 478
Query: 402 SPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTN 461
S S + E + ++K+ G L A P + D +
Sbjct: 479 SISNNSTSKRKSESATCNLV---RDINKV----GIGLVAAASSPLLVKDVICED------ 525
Query: 462 IQGLLKVALDNARIQEKQIQ---QEKKELRLELYREREIRENLERQLAVELQSRTTMQKR 518
D +I E+ ++ +++++L L L +++++ Q+ V++ S + K
Sbjct: 526 ---------DKGKIMEEVMRTYLKQQEKLNLILQKKQQL------QMEVKMLSSSKSMKE 570
Query: 519 LKKEKKTKRKLQEALEFESKRR------------EQVEQALKQATTSDSGLRMLKD 562
L +E++ +K E+L+ E +R +++EQ +KQ T DS L K+
Sbjct: 571 LTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE 626
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.1 bits (113), Expect = 2e-05
Identities = 31/87 (35%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
Query: 474 RIQEKQIQQEKKELRLELYREREIRENLERQ-LAVELQSRTTMQKRLKKEKKTKRKL-QE 531
R +E+++Q+E+ + + EL E E LERQ L E Q Q+RL++E++ +RK +E
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 532 ALEFESKRREQVEQALKQATTSDSGLR 558
E + +RREQ E+ +Q + LR
Sbjct: 314 RREQQEERREQQERREQQEERREQQLR 340
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 5/86 (5%)
Query: 474 RIQEKQIQQEKKELRLELYRERE-----IRENLERQLAVELQSRTTMQKRLKKEKKTKRK 528
R +EK+++QE++E RL+ +E RE RQ ++ + +++RLK+E+ + +
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLE 611
Query: 529 LQEALEFESKRREQVEQALKQATTSD 554
+E E KR E E+ +Q S+
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSE 637
Score = 39.7 bits (91), Expect = 0.008
Identities = 24/72 (33%), Positives = 43/72 (59%), Gaps = 5/72 (6%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVE-LQSRTTMQKRLKKEKKTKR----KLQ 530
+E++ QQE++E +L +E + L+RQ E LQ R +++L++E++ +R K +
Sbjct: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553
Query: 531 EALEFESKRREQ 542
E E +RREQ
Sbjct: 554 EEKRLEQERREQ 565
Score = 39.3 bits (90), Expect = 0.010
Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 3/73 (4%)
Query: 474 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE-A 532
R +E+Q+Q E++E RL R+R+ R E Q A + +SR Q+ ++E++ +R+ +E
Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYR--AEEQFATQEKSRREEQELWQEEEQKRRQERERK 1879
Query: 533 LEFESKRREQVEQ 545
L E RR+Q E+
Sbjct: 1880 LREEHIRRQQKEE 1892
Score = 38.5 bits (88), Expect = 0.018
Identities = 24/84 (28%), Positives = 50/84 (59%), Gaps = 10/84 (11%)
Query: 476 QEKQIQQEKKELRL----ELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE 531
+++++Q+E+++LR EL RER+ E +++L E Q R ++ +++++ +R+ QE
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 532 ALEFESKRREQV------EQALKQ 549
E + +RREQ E+ +Q
Sbjct: 327 RREQQEERREQQLRREQEERREQQ 350
Score = 38.1 bits (87), Expect = 0.023
Identities = 25/74 (33%), Positives = 48/74 (64%), Gaps = 3/74 (4%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+++QQE+++L E RE+ R+ LERQ E + + +++L +E+ KR+ QE LE
Sbjct: 1112 EEEELQQEEEQLLRE-EREKRRRQELERQYREEEEVQQE-EEQLLREEPEKRRRQE-LER 1168
Query: 536 ESKRREQVEQALKQ 549
+ + E+++Q +Q
Sbjct: 1169 QYREEEELQQEEEQ 1182
Score = 37.0 bits (84), Expect = 0.052
Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
Query: 474 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL 533
R QE++ +++++E R + R + E E+QL E + R Q R ++E++ +R+ Q
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE-RREQQLRR 366
Query: 534 EFESKRREQ 542
E E +RREQ
Sbjct: 367 EQEEERREQ 375
Score = 37.0 bits (84), Expect = 0.052
Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 5/90 (5%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKR----LKKEKKTKRKLQE 531
+E+Q+++E++E R E RE + E+QL E Q R Q R L++E++ +R+ Q
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 532 ALEFESKRREQVEQALKQATTSDSGLRMLK 561
E + RREQ E+ +Q + + LK
Sbjct: 420 RRE-QQLRREQEEERHEQKHEQERREQRLK 448
Score = 37.0 bits (84), Expect = 0.052
Identities = 23/82 (28%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
Query: 467 KVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTK 526
K AL +E+Q+ QE++E RE+ R+ ERQ E Q + ++ L++E++ +
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
Query: 527 RKLQEALEF-ESKRREQVEQAL 547
R+ + ++ + K+ +Q E+ L
Sbjct: 952 RRQERERQYRKDKKLQQKEEQL 973
Score = 36.6 bits (83), Expect = 0.068
Identities = 22/67 (32%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q ++E++E R E RE E E+QL E Q +++L++E++ +R+ Q+
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRRE-QEEERREQQLRREQEEERREQQLRRE 380
Query: 536 ESKRREQ 542
+ RREQ
Sbjct: 381 QQLRREQ 387
Score = 36.6 bits (83), Expect = 0.068
Identities = 26/76 (34%), Positives = 48/76 (63%), Gaps = 7/76 (9%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAV--ELQSRTTMQKRLKKEKKTKRKLQEAL 533
+E+++QQE+++L E RE+ R+ ERQ ELQ +++L +E++ KR+LQE
Sbjct: 992 EEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQE---EEQLLREEREKRRLQER- 1046
Query: 534 EFESKRREQVEQALKQ 549
E + + E+++Q +Q
Sbjct: 1047 ERQYREEEELQQEEEQ 1062
Score = 36.2 bits (82), Expect = 0.088
Identities = 23/84 (27%), Positives = 49/84 (58%), Gaps = 3/84 (3%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
++++ ++ ++ L+LE RE +E E+QL E + R ++RLK++++ +R LQ+ L
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERR--EQRLKRQEEEER-LQQRLRS 534
Query: 536 ESKRREQVEQALKQATTSDSGLRM 559
E + R + E+ +Q + R+
Sbjct: 535 EQQLRREQEERREQLLKREEEKRL 558
Score = 36.2 bits (82), Expect = 0.088
Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q+ +E+ E R RER+ RE E Q E R +KR ++E + + + +E ++
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
Query: 536 ESKR--REQVEQALKQ 549
E ++ RE+ E+ +Q
Sbjct: 1149 EEEQLLREEPEKRRRQ 1164
Score = 35.8 bits (81), Expect = 0.12
Identities = 22/76 (28%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q+ +E++E R RER+ R++ + Q E +KR ++E++ K + +E L+
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Query: 536 ESKR--REQVEQALKQ 549
E ++ RE+ E+ +Q
Sbjct: 999 EEEQLLREEREKRRRQ 1014
Score = 35.4 bits (80), Expect = 0.15
Identities = 24/88 (27%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 476 QEKQIQQEKKELR-LELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRK-LQEAL 533
+E+Q+++E++ R +L RE+++R E + + + ++RLK+E++ +R L+
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
Query: 534 EFESKRREQVEQALKQATTSDSGLRMLK 561
E E +E+ +Q LK+ + R LK
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLK 490
Score = 35.0 bits (79), Expect = 0.20
Identities = 23/74 (31%), Positives = 46/74 (62%), Gaps = 3/74 (4%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q+++E+ +LR E RE + E+QL E Q R +++L++E++ +R+ +E
Sbjct: 379 REQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLR--REQQLRREQQLRREQEEERHE 435
Query: 536 ESKRREQVEQALKQ 549
+ +E+ EQ LK+
Sbjct: 436 QKHEQERREQRLKR 449
Score = 35.0 bits (79), Expect = 0.20
Identities = 22/77 (28%), Positives = 48/77 (62%), Gaps = 5/77 (6%)
Query: 474 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSR-TTMQKRLKKEKKTKRKLQEA 532
R +E+Q++++++E + ++ R+ LER+ E Q R T Q++L+++++ ++ L+E
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE- 1752
Query: 533 LEFESKRREQVEQALKQ 549
E R E+ EQ L++
Sbjct: 1753 ---EQLRPEREEQQLRR 1766
Score = 34.7 bits (78), Expect = 0.26
Identities = 21/83 (25%), Positives = 46/83 (55%), Gaps = 8/83 (9%)
Query: 471 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAV--------ELQSRTTMQKRLKKE 522
D + +E+Q+ +E++E R RER+ RE E Q E + R ++++ +KE
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Query: 523 KKTKRKLQEALEFESKRREQVEQ 545
++ +++ ++ L E ++R + E+
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQER 1106
Score = 34.3 bits (77), Expect = 0.34
Identities = 20/74 (27%), Positives = 47/74 (63%), Gaps = 3/74 (4%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
++ ++QQE+++L E +R ++E ERQ E + + ++ L +E++T+R+ + LE
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQER-ERQYREEEELQQEEEQLLGEERETRRR--QELER 1078
Query: 536 ESKRREQVEQALKQ 549
+ ++ E+++Q +Q
Sbjct: 1079 QYRKEEELQQEEEQ 1092
Score = 33.9 bits (76), Expect = 0.44
Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q+ E++E R ER+ R+ E Q E R +KR ++E++ + + +E L+
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Query: 536 ESKR--REQVEQALKQ 549
E ++ RE+ E+ +Q
Sbjct: 1119 EEEQLLREEREKRRRQ 1134
Score = 33.9 bits (76), Expect = 0.44
Identities = 21/70 (30%), Positives = 39/70 (55%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q+ +E++E R ER+ RE E Q E R +KR ++E + + + +E L+
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
Query: 536 ESKRREQVEQ 545
E ++ + EQ
Sbjct: 1179 EEEQLLREEQ 1188
Score = 33.5 bits (75), Expect = 0.57
Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 12/86 (13%)
Query: 476 QEKQIQQEKKELRLELYREREIREN------------LERQLAVELQSRTTMQKRLKKEK 523
+E+Q+++E++E R E E+E RE L+R+ E + +++LK+++
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 524 KTKRKLQEALEFESKRREQVEQALKQ 549
+ +R+ + E +RREQ E+ +Q
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQ 506
Score = 33.5 bits (75), Expect = 0.57
Identities = 24/78 (30%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLER---QLAVELQSRTTMQ-KRLKKEKKTKRKLQE 531
Q K+ Q+E++ R E E RE ER QL E + R + KR ++E++ +++L+
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534
Query: 532 ALEFESKRREQVEQALKQ 549
+ ++ E+ EQ LK+
Sbjct: 535 EQQLRREQEERREQLLKR 552
Score = 33.5 bits (75), Expect = 0.57
Identities = 20/76 (26%), Positives = 46/76 (60%), Gaps = 3/76 (3%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q+QQE+++L E RE+ R+ ERQ + + + ++ L +E + +R+ + ++
Sbjct: 932 EEEQLQQEEEQLLRE-EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 536 --ESKRREQVEQALKQ 549
E + +++ EQ L++
Sbjct: 991 REEEELQQEEEQLLRE 1006
Score = 33.5 bits (75), Expect = 0.57
Identities = 24/75 (32%), Positives = 45/75 (60%), Gaps = 5/75 (6%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAV-ELQSRTTMQKRLKKEKKTKRKLQEALE 534
+E+++QQE+++L L E E R ER+ E + +++L +E++ KR+ QE LE
Sbjct: 1082 KEEELQQEEEQL---LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE-LE 1137
Query: 535 FESKRREQVEQALKQ 549
+ + E+V+Q +Q
Sbjct: 1138 RQYREEEEVQQEEEQ 1152
Score = 33.1 bits (74), Expect = 0.75
Identities = 24/74 (32%), Positives = 43/74 (58%), Gaps = 4/74 (5%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q Q+ ++E +L +E E RE E + E Q R Q+ ++E++ +R+ +E E
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERR--EQQERREQQEE-RREQQLRREQEERRE- 348
Query: 536 ESKRREQVEQALKQ 549
+ RREQ E+ +Q
Sbjct: 349 QQLRREQEEERREQ 362
Score = 33.1 bits (74), Expect = 0.75
Identities = 27/85 (31%), Positives = 50/85 (58%), Gaps = 15/85 (17%)
Query: 476 QEKQIQQEKKELRLELYREREIR-----ENLERQLAVELQSRTTMQKR----LKKEKKTK 526
+E+Q+++E++E R RE+++R E E+QL E Q R Q R L++E++ +
Sbjct: 347 REQQLRREQEEER----REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 527 RKLQEALEFESKRREQV--EQALKQ 549
R+ Q E + +R +Q+ EQ L++
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRR 427
Score = 32.7 bits (73), Expect = 0.98
Identities = 22/84 (26%), Positives = 45/84 (53%), Gaps = 10/84 (11%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL-- 533
+E+Q+ +E++E R ER+ R+ E Q E R +KR +E++ + + +E L
Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058
Query: 534 --------EFESKRREQVEQALKQ 549
E E++RR+++E+ ++
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRK 1082
Score = 32.3 bits (72), Expect = 1.3
Identities = 21/85 (24%), Positives = 44/85 (51%), Gaps = 15/85 (17%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRL---------------K 520
+E+Q+++E++E R + + +E E L+++L E Q R ++R +
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 521 KEKKTKRKLQEALEFESKRREQVEQ 545
+E++ KR+ +E + KR E+ Q
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQ 587
Score = 32.0 bits (71), Expect = 1.7
Identities = 25/84 (29%), Positives = 46/84 (54%), Gaps = 11/84 (13%)
Query: 476 QEKQIQQEKK---ELRLELYREREIREN-------LERQLAVELQSRTTMQKRLKKEKKT 525
QE++ QE++ + R +L ER+ R + L+ QL E Q ++ L++E++
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Query: 526 KRKLQEALEFESKRREQVEQALKQ 549
KR+ QE E + + EQ++Q +Q
Sbjct: 920 KRRRQEQ-ERQYREEEQLQQEEEQ 942
Score = 31.6 bits (70), Expect = 2.2
Identities = 21/76 (27%), Positives = 44/76 (57%), Gaps = 9/76 (11%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q+++E++E R + R + E E+QL E Q+ ++E++ +R+ Q E
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRRE-------QEEERREQQLRREQQLRREQ 387
Query: 536 ESKRREQV--EQALKQ 549
+ +R +Q+ EQ L++
Sbjct: 388 QLRREQQLRREQQLRR 403
Score = 31.6 bits (70), Expect = 2.2
Identities = 20/69 (28%), Positives = 36/69 (52%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q+ +E+ E R ER+ RE E Q E R +KR ++ ++ R+ +E
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Query: 536 ESKRREQVE 544
+ K+R + E
Sbjct: 1209 KRKQRYRDE 1217
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 2/71 (2%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQ-KRLKKEKKTKRKLQEALE 534
+E+Q+++E+ +LR E RE + E+QL E Q R Q +R ++E++ ++K ++
Sbjct: 385 REQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Query: 535 FESKRREQVEQ 545
+ +REQ E+
Sbjct: 444 EQRLKREQEER 454
Score = 31.2 bits (69), Expect = 2.8
Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 14/97 (14%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKR---LKKEKKTKRKLQEA 532
+E+++++E++E R L RE E + + + +L+ ++R LK E++ +R+ QE
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 533 LEFE-----SKRREQ------VEQALKQATTSDSGLR 558
E + +RREQ E+ L+Q S+ LR
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 7/73 (9%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQ------LAVELQSRTTMQKRLKKEKKTKRKL 529
+++++++E++E RLE +RE E LE++ L E Q+ LK E++ +R+
Sbjct: 586 RQQRLKREQEE-RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 530 QEALEFESKRREQ 542
Q+ + +RREQ
Sbjct: 645 QQLRREQQERREQ 657
Score = 31.2 bits (69), Expect = 2.8
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 9/83 (10%)
Query: 471 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEK------- 523
+ R Q + ++ ++E R +L + E E ++QL E Q R ++RLK+E+
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR--EQRLKREEEEERLEQ 670
Query: 524 KTKRKLQEALEFESKRREQVEQA 546
+ KR+ +E + E+ EQA
Sbjct: 671 RLKREHEEERREQELAEEEQEQA 693
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/87 (25%), Positives = 47/87 (54%), Gaps = 10/87 (11%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 535
+E+Q+ E+ E R RE++ RE E Q +++L +E++ KR+ QE E
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQ---------QEEEQLLREEREKRRRQE-WER 1018
Query: 536 ESKRREQVEQALKQATTSDSGLRMLKD 562
+ +++++++Q +Q + R L++
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQE 1045
Score = 30.8 bits (68), Expect = 3.7
Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 7/82 (8%)
Query: 475 IQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKR----LKKEKKTK---R 527
+QE++ Q +++ R +RE E+R + + +E + R Q+R LK+E++ + R
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 528 KLQEALEFESKRREQVEQALKQ 549
+ Q + + K RE+ +Q +Q
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQ 1426
Score = 30.8 bits (68), Expect = 3.7
Identities = 21/79 (26%), Positives = 46/79 (58%), Gaps = 6/79 (7%)
Query: 476 QEKQIQQEKKELRLELY-REREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALE 534
+E+Q+ QE++E +L R+R+ E E+QL + + R ++ L+ ++ ++ L+E +
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEE-EQQLRRQERDRKFREQELRSQEPERKFLEEEQQ 1523
Query: 535 FESKRRE----QVEQALKQ 549
++R+ Q EQ L++
Sbjct: 1524 LHRQQRQRKFLQEEQQLRR 1542
Score = 30.8 bits (68), Expect = 3.7
Identities = 22/91 (24%), Positives = 52/91 (57%), Gaps = 12/91 (13%)
Query: 476 QEKQIQQEKKELRLELYREREIRENL-------ERQLAVELQSRTTMQK--RLKKEKKTK 526
+E Q++++++E +L R+R+ RE E+QL + + R ++ +L+++++ +
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 527 RKLQEALEF---ESKRREQVEQALKQATTSD 554
+ LQE + E +R+ + E+ L+Q T +
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Score = 30.0 bits (66), Expect = 6.3
Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 474 RIQEKQIQQEKKELRLELYREREIRENLERQL--AVELQSRTTMQKRLKKEKKTKRKLQE 531
R +E+ Q+E++ L E RE R+ LERQ ELQ R + EK+ +++ +
Sbjct: 1051 REEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Query: 532 ALEFESKRREQVEQALKQ 549
E + +++ EQ L++
Sbjct: 1109 QCREEEELQQEEEQLLRE 1126
Score = 29.6 bits (65), Expect = 8.3
Identities = 16/69 (23%), Positives = 37/69 (53%)
Query: 474 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL 533
R+ +++ ++E ++ L +E E + E Q ELQ ++L++++ + + +E
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Query: 534 EFESKRREQ 542
+ + RREQ
Sbjct: 296 QQQRLRREQ 304
Score = 29.6 bits (65), Expect = 8.3
Identities = 24/95 (25%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Query: 456 ETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTM 515
E L + LL+ + R QE + +Q ++E ++ E+ +RE E++ EL+ +
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELE-RQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Query: 516 QKRL-KKEKKTKRKLQEALEFESKRREQVEQALKQ 549
++ L ++E++ R+ QE E +R+ + E+ L++
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQR 1207
Score = 29.6 bits (65), Expect = 8.3
Identities = 15/72 (20%), Positives = 45/72 (62%), Gaps = 3/72 (4%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSR--TTMQKRLKKEKKTKRKLQEAL 533
+E+Q++ +++E +L R+R+ RE E+QL+ + + R +++++++++ ++ L+E
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREE-EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 534 EFESKRREQVEQ 545
+ +R + +
Sbjct: 1454 QLRQERHRKFRE 1465
Score = 29.6 bits (65), Expect = 8.3
Identities = 24/82 (29%), Positives = 48/82 (58%), Gaps = 10/82 (12%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRT-TMQKRLKK----EKKTKRKLQ 530
+E+Q++++++ + R+R+ RE E QL E + + + Q+R +K E+K +R+ Q
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFRE--EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 531 EALEFESK---RREQVEQALKQ 549
E E + RR++ +Q L+Q
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQ 1615
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 47.0 bits (110), Expect = 5e-05
Identities = 27/70 (38%), Positives = 43/70 (61%), Gaps = 2/70 (2%)
Query: 471 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQ 530
+ AR+Q +++Q E + RLE RER RE LER+ + R Q+R+ +E++ R+ Q
Sbjct: 659 EKARLQRERLQLECQRQRLE--RERMERERLERERMRVERERRKEQERIHREREELRRQQ 716
Query: 531 EALEFESKRR 540
E L +E +RR
Sbjct: 717 EQLRYEQERR 726
Score = 36.2 bits (82), Expect = 0.088
Identities = 21/72 (29%), Positives = 46/72 (63%), Gaps = 7/72 (9%)
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQ-LAVELQSRTTMQKRLKKEKKTKRKLQ-EAL 533
+ ++ +Q ++E RLE + ER+ + L+R+ L +E Q ++RL++E+ + +L+ E +
Sbjct: 638 RRREREQREREQRLEAFHERKEKARLQRERLQLECQ-----RQRLERERMERERLERERM 692
Query: 534 EFESKRREQVEQ 545
E +RR++ E+
Sbjct: 693 RVERERRKEQER 704
Score = 32.7 bits (73), Expect = 0.98
Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 474 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL 533
R +E+Q Q+E++ E RERE RE R+ +E + RL++E+ ++ L
Sbjct: 621 RERERQRQREREIRETERRREREQRE---REQRLEAFHERKEKARLQRERLQLECQRQRL 677
Query: 534 EFESKRREQVEQ 545
E E RE++E+
Sbjct: 678 ERERMERERLER 689
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 46.6 bits (109), Expect = 7e-05
Identities = 38/130 (29%), Positives = 66/130 (50%), Gaps = 16/130 (12%)
Query: 453 SSVETLLTNIQGLL------KVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLA 506
S++E+ L + Q LL K++L + KQ++ EK R +L E E + NLE+Q+A
Sbjct: 1304 SALESQLQDTQELLQEENRQKLSLST---KLKQVEDEKNSFREQLEEEEEAKHNLEKQIA 1360
Query: 507 VELQSRTTMQKR-------LKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRM 559
M+K+ L+ ++ KRKLQ+ LE S+R E+ A + + + L+
Sbjct: 1361 TLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQ 1420
Query: 560 LKDTGIPDIE 569
D + D++
Sbjct: 1421 ELDDLLVDLD 1430
Score = 35.0 bits (79), Expect = 0.20
Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 8/118 (6%)
Query: 452 LSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYRER----EIRENLERQLAV 507
L+ +ETL + + K+ L E ++ E +ELR L ++ EI +LE ++
Sbjct: 868 LTEMETLQSQLMAE-KLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEE 926
Query: 508 ELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGI 565
E + +Q KK ++ ++L+E LE E R++++ + T+++ L+ L++ I
Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ---LEKVTTEAKLKKLEEEQI 981
Score = 30.4 bits (67), Expect = 4.9
Identities = 24/113 (21%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Query: 451 SLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQ 510
S++++E + ++ L + KQ+++ +K+L+ L + + R N E Q +
Sbjct: 1808 SITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAE-QYKDQAD 1866
Query: 511 SRTTMQKRLKKE-KKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKD 562
+T K+LK++ ++ + + Q A K + ++E A + A + + LK+
Sbjct: 1867 KASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKN 1919
Score = 30.0 bits (66), Expect = 6.3
Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 27/140 (19%)
Query: 450 DSLSSVET-------LLTNIQGLLK------VALDNARIQEKQIQQEKKELRLELYRERE 496
DS+ +ET L +++GL + A D + ++QQE +L ++L +R+
Sbjct: 1375 DSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQ 1434
Query: 497 IRENLERQ-------------LAVELQSRTTMQKRLKKEKKTKR-KLQEALEFESKRREQ 542
NLE++ ++ + + +EK+TK L ALE +++ +
Sbjct: 1435 SACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE 1494
Query: 543 VEQALKQATTSDSGLRMLKD 562
+E+ KQ T L KD
Sbjct: 1495 LERLNKQFRTEMEDLMSSKD 1514
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 46.6 bits (109), Expect = 7e-05
Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 6/93 (6%)
Query: 459 LTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLE--RQLAVELQSRTTMQ 516
+ N+ G + D R+Q++ ++ + R +L +E+++RE E RQL E Q R Q
Sbjct: 343 IVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQ 402
Query: 517 K----RLKKEKKTKRKLQEALEFESKRREQVEQ 545
K RL+++++ +R+ + E E +RREQ E+
Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEK 435
Score = 35.4 bits (80), Expect = 0.15
Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
Query: 458 LLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK 517
LL Q ++ + R E+Q Q+ ++E R + RE+ RE E++ EL+ R ++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQ-QRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449
Query: 518 RLKKEKKTKRKLQEALEFESKRREQVEQALK 548
++ ++ KR+++ E+ ++ E+ ++ L+
Sbjct: 450 ERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 46.6 bits (109), Expect = 7e-05
Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 6/93 (6%)
Query: 459 LTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLE--RQLAVELQSRTTMQ 516
+ N+ G + D R+Q++ ++ + R +L +E+++RE E RQL E Q R Q
Sbjct: 343 IVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQ 402
Query: 517 K----RLKKEKKTKRKLQEALEFESKRREQVEQ 545
K RL+++++ +R+ + E E +RREQ E+
Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEK 435
Score = 35.4 bits (80), Expect = 0.15
Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
Query: 458 LLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK 517
LL Q ++ + R E+Q Q+ ++E R + RE+ RE E++ EL+ R ++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQ-QRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449
Query: 518 RLKKEKKTKRKLQEALEFESKRREQVEQALK 548
++ ++ KR+++ E+ ++ E+ ++ L+
Sbjct: 450 ERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 46.6 bits (109), Expect = 7e-05
Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 6/93 (6%)
Query: 459 LTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLE--RQLAVELQSRTTMQ 516
+ N+ G + D R+Q++ ++ + R +L +E+++RE E RQL E Q R Q
Sbjct: 343 IVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQ 402
Query: 517 K----RLKKEKKTKRKLQEALEFESKRREQVEQ 545
K RL+++++ +R+ + E E +RREQ E+
Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEK 435
Score = 35.4 bits (80), Expect = 0.15
Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
Query: 458 LLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK 517
LL Q ++ + R E+Q Q+ ++E R + RE+ RE E++ EL+ R ++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQ-QRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449
Query: 518 RLKKEKKTKRKLQEALEFESKRREQVEQALK 548
++ ++ KR+++ E+ ++ E+ ++ L+
Sbjct: 450 ERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 46.6 bits (109), Expect = 7e-05
Identities = 62/258 (24%), Positives = 108/258 (41%), Gaps = 35/258 (13%)
Query: 310 NRLDLPFMMMPH----PLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGTS 365
+RL LP +PH P SLPP SV AA AQ+ P S
Sbjct: 327 SRLWLPSKSLPHLPGTPRPTSSLPPGSVK---------------AAPAQVRPP-SPGNIR 370
Query: 366 VIKERIPESPSPAPSLEENHRPGSQTS-SHTSSSVSSSPSQMDHHLERMEEVPVQIPIMK 424
+K + P +E + ++ S + V + ++ EV P M
Sbjct: 371 PVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAM- 429
Query: 425 SPLDKIQLTPGQA-LPAGFPGPFIFADSLSSVETLL--------TNIQGLLKVALDNARI 475
+P P A PA P P + + S+V T+ + ++ + R+
Sbjct: 430 APAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRL 489
Query: 476 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQ-KRLKKEKKTKRKLQ---E 531
+Q ++E++E R + ER+ RE L +++A E +R + +RL+ E+ +++ Q +
Sbjct: 490 AREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQ 549
Query: 532 ALEFESKRREQVEQALKQ 549
A E + RE+ E+A +Q
Sbjct: 550 AEERALREREEAERAQRQ 567
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/103 (29%), Positives = 58/103 (56%), Gaps = 8/103 (7%)
Query: 467 KVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK-RLKKEKKT 525
++ + AR +E+Q+Q++ +E L RERE E +RQ E + R ++ R ++EK
Sbjct: 533 RLEAEQAREKEEQLQRQAEERAL---REREEAERAQRQKEEEARVREEAERVRQEREKHF 589
Query: 526 KRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDI 568
+R+ QE LE R++++E+ +K+ +++ + D DI
Sbjct: 590 QREEQERLE----RKKRLEEIMKRTRRTEATDKKTSDQRNGDI 628
Score = 32.3 bits (72), Expect = 1.3
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 11/68 (16%)
Query: 495 REIRENLERQLAV--------ELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQA 546
RE RE E+QLA E ++R +K L++ KK +L+E + E +RR VE+
Sbjct: 71 RERREEREKQLAAREIVWLEREERARQHYEKHLEERKK---RLEEQRQKEERRRAAVEEK 127
Query: 547 LKQATTSD 554
+Q D
Sbjct: 128 RRQRLEED 135
>gi|223029420 SKI-like isoform 2 [Homo sapiens]
Length = 638
Score = 46.2 bits (108), Expect = 9e-05
Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 11/129 (8%)
Query: 64 NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
++ E + G ++ F + G++ +CLPQV + L+ L + T L I C
Sbjct: 140 SSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFT--LQQINTVCDELYIYCSRC 197
Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPGRPP 183
T +Q+ IL+ LG + C LIT D + L C R R + +V P
Sbjct: 198 TSDQLHILKVLGILPFNAPSCGLITLTDAQRL---CNALLRPRTFPQNGSV------LPA 248
Query: 184 KRSLGVLQE 192
K SL L+E
Sbjct: 249 KSSLAQLKE 257
Score = 33.1 bits (74), Expect = 0.75
Identities = 26/107 (24%), Positives = 56/107 (52%), Gaps = 21/107 (19%)
Query: 471 DNARIQEKQIQ---QEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR 527
D +I E+ ++ +++++L L L +++++ Q+ V++ S + K L +E++ +
Sbjct: 480 DKGKIMEEVMRTYLKQQEKLNLILQKKQQL------QMEVKMLSSSKSMKELTEEQQNLQ 533
Query: 528 KLQEALEFESKRR------------EQVEQALKQATTSDSGLRMLKD 562
K E+L+ E +R +++EQ +KQ T DS L K+
Sbjct: 534 KELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE 580
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 45.4 bits (106), Expect = 1e-04
Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Query: 475 IQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALE 534
+ +Q +E+KE RLE + +E LE++ A + R ++RL++E K + K + E
Sbjct: 569 LARRQTIEERKE-RLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQE 627
Query: 535 FESKRREQVEQALKQATTSDSGLRMLKDTGIPDIE 569
E +++ V + L+Q ++ G + KD I D+E
Sbjct: 628 HEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLE 662
Score = 35.8 bits (81), Expect = 0.12
Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 16/87 (18%)
Query: 474 RIQEKQIQQEKKELRLELYRERE-----------IRENLERQLAVELQSRTTM---QKRL 519
R++E++ +Q K+E R+ YRE+E ++E ER+ A + + Q+R+
Sbjct: 790 RLEERK-RQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERV 848
Query: 520 KK-EKKTKRKLQEALEFESKRREQVEQ 545
KK E+ ++K Q LE E + R + E+
Sbjct: 849 KKLEEVERKKRQRELEIEERERRREEE 875
Score = 31.2 bits (69), Expect = 2.8
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 456 ETLLTNIQGLLKVALDNARIQEKQIQ-QEKKELRLELYREREIRENL---ERQLAVELQS 511
E +T +Q + AL++ + ++ ++ +RL+ R+ E L E +LA E +
Sbjct: 730 EERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHN 789
Query: 512 RTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQ 549
R +KR +KE++ +E E E +R E EQ LK+
Sbjct: 790 RLEERKRQRKEERRITYYREKEEEEQRRAE--EQMLKE 825
>gi|67763814 death-inducing-protein [Homo sapiens]
Length = 578
Score = 43.9 bits (102), Expect = 4e-04
Identities = 39/127 (30%), Positives = 66/127 (51%), Gaps = 17/127 (13%)
Query: 399 VSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETL 458
++ SP+ D E +E+P+++P SP D +L PAG PG I A +
Sbjct: 21 LAESPNASD--TECSDEIPLKVP-RTSPRDSEELRD----PAG-PGTLIMATGVQDFNRT 72
Query: 459 ----LTNIQGLLKVALDNARIQEKQIQQEKKE-----LRLELYREREIRENLERQLAVEL 509
L I+G L++AL ++++++ ++E LR EL RER+ R LE+++ L
Sbjct: 73 EFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVL 132
Query: 510 QSRTTMQ 516
++RT Q
Sbjct: 133 KARTEEQ 139
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 43.1 bits (100), Expect = 7e-04
Identities = 23/82 (28%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
Query: 467 KVALDNARIQEKQIQQEKKELRLE---LYREREIRENLERQLAVELQSRTTMQKRLKKEK 523
++ + R + +++Q+E++ L +E L RER RE LER+ Q R +R+ +E+
Sbjct: 629 RIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARER 688
Query: 524 KTKRKLQEALEFESKRREQVEQ 545
+ R+ Q+ L +E ++R +++
Sbjct: 689 EELRRQQQQLRYEQEKRNSLKR 710
Score = 38.1 bits (87), Expect = 0.023
Identities = 22/85 (25%), Positives = 50/85 (58%), Gaps = 5/85 (5%)
Query: 466 LKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKT 525
L+ A++ R +E ++ ++ R+ + RERE RE L+R E + +++L++E+
Sbjct: 607 LRRAMELRRRREIAERERRERERIRIIREREERERLQR----ERERLEIERQKLERERME 662
Query: 526 KRKLQ-EALEFESKRREQVEQALKQ 549
+ +L+ E + E +RR++ E+ ++
Sbjct: 663 RERLERERIRIEQERRKEAERIARE 687
Score = 33.5 bits (75), Expect = 0.57
Identities = 23/74 (31%), Positives = 43/74 (58%), Gaps = 3/74 (4%)
Query: 474 RIQEKQIQQEKKELRLELYREREI--RENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE 531
R++E ++ E+ +EL R REI RE ER+ ++ R ++RL++E++ ++
Sbjct: 596 RLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREE-RERLQRERERLEIERQ 654
Query: 532 ALEFESKRREQVEQ 545
LE E RE++E+
Sbjct: 655 KLERERMERERLER 668
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,981,718
Number of Sequences: 37866
Number of extensions: 1296987
Number of successful extensions: 10169
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 182
Number of HSP's successfully gapped in prelim test: 511
Number of HSP's that attempted gapping in prelim test: 7042
Number of HSP's gapped (non-prelim): 3024
length of query: 599
length of database: 18,247,518
effective HSP length: 108
effective length of query: 491
effective length of database: 14,157,990
effective search space: 6951573090
effective search space used: 6951573090
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.