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Search of human proteins with 110578663
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
(352 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110578663 hypothetical protein LOC203074 [Homo sapiens] 736 0.0
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 186 4e-47
gi|4503627 coagulation factor XI precursor [Homo sapiens] 183 2e-46
gi|13994276 marapsin [Homo sapiens] 169 4e-42
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 165 6e-41
gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 164 1e-40
gi|4506153 prostasin preproprotein [Homo sapiens] 163 2e-40
gi|58218970 protease, serine, 36 [Homo sapiens] 162 3e-40
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 161 7e-40
gi|11545839 protease, serine, 22 [Homo sapiens] 160 2e-39
gi|223942069 enterokinase precursor [Homo sapiens] 159 3e-39
gi|11415040 matriptase [Homo sapiens] 159 4e-39
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 159 4e-39
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 159 5e-39
gi|117956391 protease, serine, 33 [Homo sapiens] 158 8e-39
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 156 3e-38
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 156 3e-38
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 156 3e-38
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 155 7e-38
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 154 1e-37
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 154 1e-37
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr... 151 7e-37
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 151 7e-37
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 151 7e-37
gi|29244926 corin [Homo sapiens] 151 7e-37
gi|169172917 PREDICTED: hypothetical protein LOC346702 [Homo sap... 151 1e-36
gi|4503625 coagulation factor X preproprotein [Homo sapiens] 151 1e-36
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 150 2e-36
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 150 2e-36
gi|10518503 coagulation factor VII isoform b precursor [Homo sap... 149 4e-36
>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
Length = 352
Score = 736 bits (1899), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MLLFSVLLLLSLVTGTQLGPRTPLPEAGVAILGRARGAHRPQPPHPPSPVSECGDRSIFE 60
MLLFSVLLLLSLVTGTQLGPRTPLPEAGVAILGRARGAHRPQPPHPPSPVSECGDRSIFE
Sbjct: 1 MLLFSVLLLLSLVTGTQLGPRTPLPEAGVAILGRARGAHRPQPPHPPSPVSECGDRSIFE 60
Query: 61 GRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEEL 120
GRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEEL
Sbjct: 61 GRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEEL 120
Query: 121 SVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQ 180
SVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQ
Sbjct: 121 SVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQ 180
Query: 181 PGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKN 240
PGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKN
Sbjct: 181 PGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKN 240
Query: 241 ESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQ 300
ESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQ
Sbjct: 241 ESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQ 300
Query: 301 LEGRPFNAEKRRTSVKQKPMGSPVSGVPEPGSPRSWLLLCPLSHVLFRAILY 352
LEGRPFNAEKRRTSVKQKPMGSPVSGVPEPGSPRSWLLLCPLSHVLFRAILY
Sbjct: 301 LEGRPFNAEKRRTSVKQKPMGSPVSGVPEPGSPRSWLLLCPLSHVLFRAILY 352
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 186 bits (471), Expect = 4e-47
Identities = 103/257 (40%), Positives = 151/257 (58%), Gaps = 18/257 (7%)
Query: 54 GDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQAR---SEPFCGGSILNKWWILTAAHCL 110
GD S+ +T +RI GG + GE+PWQVS+Q + CGGS++ W+LTAAHC
Sbjct: 378 GDNSVCTTKTS-TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF 436
Query: 111 YSEELFP--EELSVVLGTNDLT--SPSMEIKEVASIILHKDFKRANMDNDIALLLLASPI 166
L S +L +D+T +P +IKE II+H+++K + ++DIAL+ L +P+
Sbjct: 437 DGLPLQDVWRIYSGILNLSDITKDTPFSQIKE---IIIHQNYKVSEGNHDIALIKLQAPL 493
Query: 167 KLDDLKVPICLPTQPGPAT-WRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKM 225
+ + PICLP++ +T + CWV GWG + +K ++ L K + ++ EEC K
Sbjct: 494 NYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSK--EKGEIQNILQKVNIPLVTNEECQKR 551
Query: 226 FP--KLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPG 283
+ K+T+ M+CAGYK DACKGDSGGPLVC + W VGI SWG+ C + PG
Sbjct: 552 YQDYKITQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGEGCARREQPG 609
Query: 284 IYTSLVNYNLWIEKVTQ 300
+YT + Y WI + TQ
Sbjct: 610 VYTKVAEYMDWILEKTQ 626
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 183 bits (465), Expect = 2e-46
Identities = 105/246 (42%), Positives = 140/246 (56%), Gaps = 21/246 (8%)
Query: 67 RITGGMEAEVGEFPWQVSIQARSEP---FCGGSILNKWWILTAAHCLYSEELFPEELSVV 123
RI GG + GE+PWQV++ S CGGSI+ WILTAAHC Y E P+ L V
Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVES-PKILRVY 445
Query: 124 LGTNDLTSPSMEIKE------VASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICL 177
G + + EIKE V II+H +K A DIALL L + + D + PICL
Sbjct: 446 SGILNQS----EIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICL 501
Query: 178 PTQPGP-ATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFP--KLTKNML 234
P++ + +CWV GWG DK ++ L KA + ++ EEC K + K+T M+
Sbjct: 502 PSKGDRNVIYTDCWVTGWGYRKLRDK--IQNTLQKAKIPLVTNEECQKRYRGHKITHKMI 559
Query: 235 CAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLW 294
CAGY+ DACKGDSGGPL C + E W+ VGI SWG+ C ++ PG+YT++V Y W
Sbjct: 560 CAGYREGGKDACKGDSGGPLSC--KHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDW 617
Query: 295 IEKVTQ 300
I + TQ
Sbjct: 618 ILEKTQ 623
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 169 bits (427), Expect = 4e-42
Identities = 95/256 (37%), Positives = 137/256 (53%), Gaps = 25/256 (9%)
Query: 61 GRTRY-SRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEE 119
GR R +R+ GG + + GE+PWQVSIQ FCGGS++ + W+LTAAHC +
Sbjct: 27 GRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHC-FRNTSETSL 85
Query: 120 LSVVLGTNDLTSPS-----MEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVP 174
V+LG L P +++V S L ++ D+AL+ L +P+ + +P
Sbjct: 86 YQVLLGARQLVQPGPHAMYARVRQVESNPL---YQGTASSADVALVELEAPVPFTNYILP 142
Query: 175 ICLPTQPGP--ATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMF------ 226
+CLP P T CWV GWG + D L K + I+D +C+ ++
Sbjct: 143 VCLP-DPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEF 201
Query: 227 ---PKLTKN-MLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTP 282
PK KN MLCAG++ DACKGDSGGPLVC G+ W Q G+ISWG+ C +N P
Sbjct: 202 GYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCL--VGQSWLQAGVISWGEGCARQNRP 259
Query: 283 GIYTSLVNYNLWIEKV 298
G+Y + ++ WI ++
Sbjct: 260 GVYIRVTAHHNWIHRI 275
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 165 bits (417), Expect = 6e-41
Identities = 95/264 (35%), Positives = 144/264 (54%), Gaps = 15/264 (5%)
Query: 50 VSECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHC 109
+ ECG R E TR + GG A GE PWQVS++ S FCG +++ W+L+AAHC
Sbjct: 489 LQECGARPAMEKPTR---VVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHC 545
Query: 110 LYSEELFPEELSVVLGTNDLTSPSMEIKEVA--SIILHKDFKRANMDNDIALLLLASPIK 167
++ E++ LGT L ++ ++LH + +D D+A+L LASP+
Sbjct: 546 FNHTKV--EQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLA 603
Query: 168 LDDLKVPICLP--TQPGPATWRECWVAGWGQTNAADKNSVKTDLM-KAPMVIMDWEECSK 224
+ P+CLP Q P R+C ++GWG N + N+ K +L+ KA + I+D + CS
Sbjct: 604 FNKYIQPVCLPLAIQKFP-VGRKCMISGWG--NTQEGNATKPELLQKASVGIIDQKTCSV 660
Query: 225 MFP-KLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPG 283
++ LT M+CAG+ D+C+GDSGGPL C PG +Y GI+SWG C + PG
Sbjct: 661 LYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPG-VFYLAGIVSWGIGCAQVKKPG 719
Query: 284 IYTSLVNYNLWIEKVTQLEGRPFN 307
+YT + WI ++ + P +
Sbjct: 720 VYTRITRLKGWILEIMSSQPLPMS 743
Score = 163 bits (413), Expect = 2e-40
Identities = 99/296 (33%), Positives = 148/296 (50%), Gaps = 31/296 (10%)
Query: 20 PRTPLPEAGVAILGRARGAH--------RPQPPHPPSP-------VSECGDRSIFEGRTR 64
P P P A + G+ + R Q P P +P + +CG
Sbjct: 769 PSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCG-----LAPAA 823
Query: 65 YSRITGGMEAEVGEFPWQVSIQARS-EPFCGGSILNKWWILTAAHC--LYSEELFPEELS 121
+RI GG A GE+PWQVS+ R E CG ++ + W+L+AAHC +Y + P++ +
Sbjct: 824 LTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGD---PKQWA 880
Query: 122 VVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLP-TQ 180
LGT L+ +++ VA I H + +D D+ALL LA P++ L PICLP
Sbjct: 881 AFLGTPFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPA 940
Query: 181 PGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFP-KLTKNMLCAGYK 239
P P C + GWG + + S+ L KA + ++ + C + +P +++ MLCAG+
Sbjct: 941 PRPPDGTRCVITGWG--SVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFP 998
Query: 240 NESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWI 295
D+C GD+GGPL C EP +W G+ SWG CG + PG+YT + WI
Sbjct: 999 QGGVDSCSGDAGGPLACR-EPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWI 1053
Score = 160 bits (404), Expect = 2e-39
Identities = 99/284 (34%), Positives = 147/284 (51%), Gaps = 25/284 (8%)
Query: 67 RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGT 126
RI GGMEA GEFPWQ S++ E FCG +I+N W+++AAHC ++E P + +G
Sbjct: 202 RIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHC-FNEFQDPTKWVAYVGA 260
Query: 127 NDL--TSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLP--TQPG 182
L + S +V I+ H + D D+A+L L SP+ P+CLP T
Sbjct: 261 TYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIF 320
Query: 183 PATWRECWVAGWGQTNAADKNSVKTD-LMKAPMVIMDWEECSKMF-PKLTKNMLCAGYKN 240
P + ++C ++GWG + VK + L KA + ++D C+ ++ LT M+CAGY +
Sbjct: 321 PPS-KKCLISGWGYLK--EDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLD 377
Query: 241 ESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQ 300
D+C+GDSGGPLVC EP +++ GI+SWG C E PG+Y + WI + T
Sbjct: 378 GKVDSCQGDSGGPLVC-EEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEAT- 435
Query: 301 LEGRPFNAEKRRTSVKQKPMGSPVSGVPE---PGSPRSWLLLCP 341
+ S+ P +P P P SP S ++ P
Sbjct: 436 ----------TKASMPLAPTMAPAPAAPSTAWPTSPESPVVSTP 469
>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
Length = 717
Score = 164 bits (414), Expect = 1e-40
Identities = 96/256 (37%), Positives = 133/256 (51%), Gaps = 12/256 (4%)
Query: 52 ECGDRSIFEGRT------RYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILT 105
+C D S EG T RI GG + G +PWQVS+ +CG S++++ W+L+
Sbjct: 458 DCPDGSDEEGCTCSRSSSALHRIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLS 517
Query: 106 AAHCLYSEELF-PEELSVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLL-- 162
AAHC + L P + LG + + + V I++H+ + D DIALL L
Sbjct: 518 AAHCFHGNRLSDPTPWTAHLGMY-VQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSI 576
Query: 163 ASPIKLDDLKVPICLP-TQPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEE 221
A P L L PIC+P T + +CWV GWG+ + AD N L +A + ++D
Sbjct: 577 AWPETLKQLIQPICIPPTGQRVRSGEKCWVTGWGRRHEAD-NKGSLVLQQAEVELIDQTL 635
Query: 222 CSKMFPKLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNT 281
C + +T MLCAG + DACKGDSGGPL C + KW GI+SWG G N
Sbjct: 636 CVSTYGIITSRMLCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNF 695
Query: 282 PGIYTSLVNYNLWIEK 297
PG+YT + N+ WI K
Sbjct: 696 PGVYTRVSNFVPWIHK 711
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 163 bits (412), Expect = 2e-40
Identities = 97/252 (38%), Positives = 134/252 (53%), Gaps = 16/252 (6%)
Query: 66 SRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLG 125
+RITGG A G++PWQVSI CGGS++++ W+L+AAHC SE E V LG
Sbjct: 43 ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEH-HKEAYEVKLG 101
Query: 126 TNDLTSPSMEIK--EVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGP 183
+ L S S + K + II H + + DIALL L+ PI PICLP
Sbjct: 102 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANAS 161
Query: 184 -ATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMF-----PK----LTKNM 233
C V GWG + L + + ++ E C+ ++ P+ + ++M
Sbjct: 162 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDM 221
Query: 234 LCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNL 293
+CAGY DAC+GDSGGPL C E WY GI+SWG +CG +N PG+YT +Y
Sbjct: 222 VCAGYVEGGKDACQGDSGGPLSCPVE--GLWYLTGIVSWGDACGARNRPGVYTLASSYAS 279
Query: 294 WIE-KVTQLEGR 304
WI+ KVT+L+ R
Sbjct: 280 WIQSKVTELQPR 291
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 162 bits (411), Expect = 3e-40
Identities = 100/292 (34%), Positives = 147/292 (50%), Gaps = 23/292 (7%)
Query: 66 SRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELF--PEELSVV 123
+RI GG A+ G +PWQVS+ CGGS++ W+L+AAHC + E SV+
Sbjct: 45 ARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVL 104
Query: 124 LGTNDLTSP--SMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQP 181
LG + P + VA+I++ ++ + + D+ALL LASP L P+CLP
Sbjct: 105 LGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRAS 164
Query: 182 GP-ATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFP---------KLTK 231
CW GWG AD + L + + ++ C ++ ++
Sbjct: 165 HRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILP 224
Query: 232 NMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNY 291
MLCAGY D C+GDSGGPLVC E G +W+Q GI S+G CG +N PG++T++ Y
Sbjct: 225 GMLCAGYPEGRRDTCQGDSGGPLVC--EEGGRWFQAGITSFGFGCGRRNRPGVFTAVATY 282
Query: 292 NLWI-EKVTQLE-GRPFNAEKRRT-SVKQKPMGSPVS-GVPEPGS---PRSW 336
WI E+V E G F + ++T S Q+P + +PE G P +W
Sbjct: 283 EAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAW 334
Score = 64.3 bits (155), Expect = 2e-10
Identities = 63/248 (25%), Positives = 100/248 (40%), Gaps = 36/248 (14%)
Query: 71 GMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLY---SEELFPEELSVVLGTN 127
G G +PW+ + C G+++++ W+L A C S + P +L
Sbjct: 326 GKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLD---AWR 382
Query: 128 DLTSPSMEIKEVASIILHKDFKRANMDN--DIALLLLASPIKLDDLKVPICLPTQ----- 180
L + VA ++ H++ A+ DN D+ALL L +P+ L P+CLP
Sbjct: 383 VLLPSRPRAERVARLVQHEN---ASWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFL 439
Query: 181 PGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEEC-------SKMFPKLTKNM 233
PG C +A WG+ A L++A ++ W C + P +
Sbjct: 440 PG----SRCRLARWGRGEPALGPGA---LLEAELLGGWWCHCLYGRQGAAVPLPGDPPHA 492
Query: 234 LCAGY-KNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYN 292
LC Y + E +C DS L+C E W+ GI + C P + L +
Sbjct: 493 LCPAYQEKEEVGSCWNDSRWSLLCQEE--GTWFLAGIRDFPSGC---LRPRAFFPLQTHG 547
Query: 293 LWIEKVTQ 300
WI VT+
Sbjct: 548 PWISHVTR 555
Score = 53.9 bits (128), Expect = 2e-07
Identities = 50/197 (25%), Positives = 77/197 (39%), Gaps = 11/197 (5%)
Query: 79 FPWQVSIQARSEPFCGGSILNKWWILTAAHC-LYSEELFPEELSVVLGTNDLTSPSMEIK 137
+PW + + C G +L W+L A HC L + V LG +S +
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQ 660
Query: 138 EVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECWVAGWGQT 197
+I + + + +ALL L+S ++ +PICL G CWV GW +
Sbjct: 661 VSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICL-HPAGIPPGASCWVLGWKEP 719
Query: 198 NAADKNSVKTDLMKAPMVIMDWEECSKMFPK-LTKNMLCAGYKNESYDACKGDSGGPLVC 256
D+ V A + I+ C ++ L LC Y + C+ S PL+C
Sbjct: 720 Q--DRVPV-----AAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLC 772
Query: 257 TPEPGEKWYQVGIISWG 273
G W VG+ G
Sbjct: 773 QMTEG-SWILVGMAVQG 788
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 161 bits (408), Expect = 7e-40
Identities = 97/262 (37%), Positives = 145/262 (55%), Gaps = 28/262 (10%)
Query: 53 CGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYS 112
CG R I ++ + GG+E+ G +PWQ S++ R CGGS+L++ W+L+AAHC +
Sbjct: 46 CGHREI------HALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHC-FQ 98
Query: 113 EELFPEELSVVLGTNDLTSPSMEIK--------EVASIILHKDFKRANMDNDIALLLLAS 164
+ +P E +V LG +LTS +V II++ D + NDIALL LAS
Sbjct: 99 KHYYPSEWTVQLG--ELTSRPTPWNLRAYSSRYKVQDIIVNPD-ALGVLRNDIALLRLAS 155
Query: 165 PIKLDDLKVPICLPTQPGPATWR-ECWVAGWGQTN-AADKNSVKTDLMKAPMVIMDWEEC 222
+ + PIC+ + R +CWV GWG + + +L +A + I++ C
Sbjct: 156 SVTYNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRC 215
Query: 223 SKMFPK------LTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSC 276
+ +F + + +M CAG ++ S D CKGDSGGPLVC + WYQVGI+SWG C
Sbjct: 216 NYLFEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVC--DKDGLWYQVGIVSWGMDC 273
Query: 277 GEKNTPGIYTSLVNYNLWIEKV 298
G+ N PG+YT++ Y WI +V
Sbjct: 274 GQPNRPGVYTNISVYFHWIRRV 295
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 160 bits (404), Expect = 2e-39
Identities = 106/293 (36%), Positives = 145/293 (49%), Gaps = 35/293 (11%)
Query: 27 AGVAILGRARGAHRPQPPHPPSPVSECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQ 86
A AIL AR P PP+ CG + +R+ GG ++ E+PW VSIQ
Sbjct: 25 ASTAILNAAR------IPVPPA----CGKPQ------QLNRVVGGEDSTDSEWPWIVSIQ 68
Query: 87 ARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEIKE--VASIIL 144
C GS+L W++TAAHC P SV+LG L +P ++ VA +
Sbjct: 69 KNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEP 128
Query: 145 HKDFK-RANMDNDIALLLLASPIKLDDLKVPICLPTQP---GPATWRECWVAGWGQTNAA 200
H + + DIAL+ L I+ + +PICLP P T CW++GWG
Sbjct: 129 HPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNT--HCWISGWGSIQDG 186
Query: 201 DKNSVKTDLMKAPMVIMDWEECSKMFPK------LTKNMLCAGYKNESYDACKGDSGGPL 254
L K + I+D E CS ++ + +T++MLCAGY DAC GDSGGPL
Sbjct: 187 VPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPL 246
Query: 255 VCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKV---TQLEGR 304
+C + W GIISWG+ C E+N PG+Y SL + W+EK+ QL GR
Sbjct: 247 MCQVDGA--WLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGR 297
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 159 bits (403), Expect = 3e-39
Identities = 80/240 (33%), Positives = 131/240 (54%), Gaps = 18/240 (7%)
Query: 67 RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLG- 125
+I GG A+ G +PW V + CG S+++ W+++AAHC+Y L P + + +LG
Sbjct: 784 KIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGL 843
Query: 126 --TNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQ--- 180
++LTSP + + I+++ + R DNDIA++ L + D PICLP +
Sbjct: 844 HMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQV 903
Query: 181 --PGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPK--LTKNMLCA 236
PG R C +AGWG + + L +A + ++ E C + P+ +T+NM+CA
Sbjct: 904 FPPG----RNCSIAGWG--TVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICA 957
Query: 237 GYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIE 296
GY+ D+C+GDSGGPL+C + +W+ G+ S+G C N PG+Y + + WI+
Sbjct: 958 GYEEGGIDSCQGDSGGPLMC--QENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQ 1015
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 159 bits (402), Expect = 4e-39
Identities = 90/259 (34%), Positives = 142/259 (54%), Gaps = 19/259 (7%)
Query: 52 ECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEP-FCGGSILNKWWILTAAHCL 110
+CG RS TR +R+ GG +A+ GE+PWQVS+ A + CG S+++ W+++AAHC
Sbjct: 603 DCGLRSF----TRQARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCY 658
Query: 111 YSEELF----PEELSVVLGTNDLT---SPSMEIKEVASIILHKDFKRANMDNDIALLLLA 163
+ F P + + LG +D + +P ++ + + II H F D DIALL L
Sbjct: 659 IDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELE 718
Query: 164 SPIKLDDLKVPICLP--TQPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEE 221
P + + PICLP + PA + WV GWG T ++ L K + +++
Sbjct: 719 KPAEYSSMVRPICLPDASHVFPAG-KAIWVTGWGHTQYGGTGALI--LQKGEIRVINQTT 775
Query: 222 CSKMFPK-LTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKN 280
C + P+ +T M+C G+ + D+C+GDSGGPL G + +Q G++SWG C ++N
Sbjct: 776 CENLLPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADG-RIFQAGVVSWGDGCAQRN 834
Query: 281 TPGIYTSLVNYNLWIEKVT 299
PG+YT L + WI++ T
Sbjct: 835 KPGVYTRLPLFRDWIKENT 853
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 159 bits (402), Expect = 4e-39
Identities = 86/242 (35%), Positives = 130/242 (53%), Gaps = 16/242 (6%)
Query: 66 SRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEEL-SVVL 124
SRI GG + GE+PWQ S+Q R CGG+++ W++TAAHC + + L +V L
Sbjct: 575 SRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFL 634
Query: 125 GT--NDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPT--- 179
G + P +V+ ++LH + + D D+ALL L P+ P+CLP
Sbjct: 635 GKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSH 694
Query: 180 --QPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFP-KLTKNMLCA 236
+PG CW+ GWG + + L K + ++ + CS+++ ++T MLCA
Sbjct: 695 FFEPG----LHCWITGWGALR--EGGPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCA 748
Query: 237 GYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIE 296
GY+ DAC+GDSGGPLVC G +W+ G++SWG CG N G+YT + WI+
Sbjct: 749 GYRKGKKDACQGDSGGPLVCKALSG-RWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQ 807
Query: 297 KV 298
+V
Sbjct: 808 QV 809
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 159 bits (401), Expect = 5e-39
Identities = 91/259 (35%), Positives = 137/259 (52%), Gaps = 15/259 (5%)
Query: 51 SECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCL 110
S CG R++ RI GG A ++PWQVS+ + CGG++++ W+LTAAHC
Sbjct: 315 SHCGLRAMT------GRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCF 368
Query: 111 Y-SEELFPEELSVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLD 169
+ + E E V GT++L E +A II++ ++ D DIAL+ L+ P+ L
Sbjct: 369 FVTREKVLEGWKVYAGTSNL-HQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLS 427
Query: 170 DLKVPICLPTQPGPATWRE-CWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMF-- 226
P CLP + E CW+ G+G+T D + L + + ++D+++C+
Sbjct: 428 AHIHPACLPMHGQTFSLNETCWITGFGKTRETD-DKTSPFLREVQVNLIDFKKCNDYLVY 486
Query: 227 -PKLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIY 285
LT M+CAG D+C+GDSGGPLVC E +WY G+ SWG CG++N PG+Y
Sbjct: 487 DSYLTPRMMCAGDLRGGRDSCQGDSGGPLVC--EQNNRWYLAGVTSWGTGCGQRNKPGVY 544
Query: 286 TSLVNYNLWIEKVTQLEGR 304
T + WI + E R
Sbjct: 545 TKVTEVLPWIYSKMESEVR 563
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 158 bits (399), Expect = 8e-39
Identities = 97/259 (37%), Positives = 126/259 (48%), Gaps = 21/259 (8%)
Query: 54 GDRSIFEGRTRYS-RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYS 112
G +S G+ R S RI GG + GE+PWQ SIQ R CGGS++ W+LTAAHC +
Sbjct: 22 GRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHC-FP 80
Query: 113 EELFPEELSVVLGTNDL--TSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDD 170
P E V LG L TSP V ++L D+ D+ALL L P+ L
Sbjct: 81 RRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSA 140
Query: 171 LKVPICLP---TQPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMF- 226
P+CLP +P P T C V GWG L + ++D C ++
Sbjct: 141 RVQPVCLPVPGARPPPGT--PCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYH 198
Query: 227 -----PKLTK----NMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCG 277
P+ + LCAGY DAC+GDSGGPL C W VG++SWGK C
Sbjct: 199 VGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCL--QSGSWVLVGVVSWGKGCA 256
Query: 278 EKNTPGIYTSLVNYNLWIE 296
N PG+YTS+ Y+ WI+
Sbjct: 257 LPNRPGVYTSVATYSPWIQ 275
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 156 bits (394), Expect = 3e-38
Identities = 89/241 (36%), Positives = 128/241 (53%), Gaps = 15/241 (6%)
Query: 64 RYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVV 123
R SR+ GG+ A ++PWQVS+Q + CGGS++++ W+LTAAHC++ + ++
Sbjct: 159 RVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLL 218
Query: 124 LGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGP 183
G + K + II +F A + +DIAL LLA + P CLP +
Sbjct: 219 AG---IGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFE 275
Query: 184 A-TWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPK--------LTKNML 234
ECWV GWGQ + + + L + + IM E+C +M +T+ +
Sbjct: 276 VEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTV 335
Query: 235 CAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLW 294
C GY ++ DAC+GDSGGPLVC E W QVGI+SWG CG K PG+YT + Y W
Sbjct: 336 C-GYNDQGKDACQGDSGGPLVC--ELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKW 392
Query: 295 I 295
I
Sbjct: 393 I 393
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 156 bits (394), Expect = 3e-38
Identities = 89/241 (36%), Positives = 128/241 (53%), Gaps = 15/241 (6%)
Query: 64 RYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVV 123
R SR+ GG+ A ++PWQVS+Q + CGGS++++ W+LTAAHC++ + ++
Sbjct: 159 RVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLL 218
Query: 124 LGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGP 183
G + K + II +F A + +DIAL LLA + P CLP +
Sbjct: 219 AG---IGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFE 275
Query: 184 A-TWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPK--------LTKNML 234
ECWV GWGQ + + + L + + IM E+C +M +T+ +
Sbjct: 276 VEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTV 335
Query: 235 CAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLW 294
C GY ++ DAC+GDSGGPLVC E W QVGI+SWG CG K PG+YT + Y W
Sbjct: 336 C-GYNDQGKDACQGDSGGPLVC--ELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKW 392
Query: 295 I 295
I
Sbjct: 393 I 393
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 156 bits (394), Expect = 3e-38
Identities = 89/241 (36%), Positives = 128/241 (53%), Gaps = 15/241 (6%)
Query: 64 RYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVV 123
R SR+ GG+ A ++PWQVS+Q + CGGS++++ W+LTAAHC++ + ++
Sbjct: 159 RVSRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLL 218
Query: 124 LGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGP 183
G + K + II +F A + +DIAL LLA + P CLP +
Sbjct: 219 AG---IGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFE 275
Query: 184 A-TWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPK--------LTKNML 234
ECWV GWGQ + + + L + + IM E+C +M +T+ +
Sbjct: 276 VEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTV 335
Query: 235 CAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLW 294
C GY ++ DAC+GDSGGPLVC E W QVGI+SWG CG K PG+YT + Y W
Sbjct: 336 C-GYNDQGKDACQGDSGGPLVC--ELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKW 392
Query: 295 I 295
I
Sbjct: 393 I 393
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 155 bits (391), Expect = 7e-38
Identities = 100/277 (36%), Positives = 134/277 (48%), Gaps = 32/277 (11%)
Query: 28 GVAILGRARGAHRPQPPHPPSPVSECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQA 87
GV++ G RPQ VS+ G RI GG A G +PWQ S++
Sbjct: 16 GVSLRTLQPGCGRPQ-------VSDAG-----------GRIVGGHAAPAGAWPWQASLRL 57
Query: 88 RSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEIKEVASIILHKD 147
R CGGS+L+ W+LTAAHC +S L + V LG ++T S V IILH
Sbjct: 58 RRVHVCGGSLLSPQWVLTAAHC-FSGSLNSSDYQVHLGELEITL-SPHFSTVRQIILHSS 115
Query: 148 -FKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGP-ATWRECWVAGWGQTNAADKNSV 205
+ DIAL+ L+ P+ L +P+CLP CWV GWG T +
Sbjct: 116 PSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPP 175
Query: 206 KTDLMKAPMVIMDWEECSKMFPK-----LTKNMLCAGYKNESYDACKGDSGGPLVCTPEP 260
L + + ++D E C + +P L +MLCA DAC+ DSGGPLVC +
Sbjct: 176 PYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCA---RGPGDACQDDSGGPLVC--QV 230
Query: 261 GEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEK 297
W Q GI+SWG+ CG N PG+YT + Y WI +
Sbjct: 231 NGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRR 267
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 154 bits (389), Expect = 1e-37
Identities = 94/259 (36%), Positives = 132/259 (50%), Gaps = 21/259 (8%)
Query: 51 SECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCL 110
SECG R + SRI GG G +PWQ S+ CGGS+L W++TAAHC+
Sbjct: 207 SECGARPLA------SRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCM 260
Query: 111 YS---EELFPEELSVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIK 167
+S L + L ++ P V II H + N D D+ALL L + +
Sbjct: 261 HSFRLARLSSWRVHAGLVSHSAVRPHQGAL-VERIIPHPLYSAQNHDYDVALLRLQTALN 319
Query: 168 LDDLKVPICLPT--QPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMV-IMDWEECSK 224
D +CLP Q P R CWV+GWG T+ + ++ +D+++ +V + + C+
Sbjct: 320 FSDTVGAVCLPAKEQHFPKGSR-CWVSGWGHTHPS--HTYSSDMLQDTVVPLFSTQLCNS 376
Query: 225 ---MFPKLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNT 281
LT MLCAGY + DAC+GDSGGPLVC G+ W VG++SWG+ C E N
Sbjct: 377 SCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVC--PDGDTWRLVGVVSWGRGCAEPNH 434
Query: 282 PGIYTSLVNYNLWIEKVTQ 300
PG+Y + + WI Q
Sbjct: 435 PGVYAKVAEFLDWIHDTAQ 453
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 154 bits (388), Expect = 1e-37
Identities = 89/251 (35%), Positives = 134/251 (53%), Gaps = 17/251 (6%)
Query: 53 CGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYS 112
CG R R SRI GG + + ++PWQ S+Q + CGGS++ WI+TAAHC+Y
Sbjct: 207 CGHR-----RGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYD 261
Query: 113 EELFPEELSVVLGTNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLK 172
L P+ ++ +G L V I+ H +K + NDIAL+ LA P+ +++
Sbjct: 262 LYL-PKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMI 320
Query: 173 VPICLP-TQPGPATWRECWVAGWGQT--NAADKNSVKTDLMKAPMVIMDWEECSKMFPK- 228
P+CLP ++ + CW +GWG T A D + V L A + ++ + C+
Sbjct: 321 QPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPV---LNHAAVPLISNKICNHRDVYG 377
Query: 229 --LTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYT 286
++ +MLCAGY D+C+GDSGGPLVC + W VG S+G C E N PG+YT
Sbjct: 378 GIISPSMLCAGYLTGGVDSCQGDSGGPLVC--QERRLWKLVGATSFGIGCAEVNKPGVYT 435
Query: 287 SLVNYNLWIEK 297
+ ++ WI +
Sbjct: 436 RVTSFLDWIHE 446
>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
precursor [Homo sapiens]
Length = 686
Score = 151 bits (382), Expect = 7e-37
Identities = 92/264 (34%), Positives = 140/264 (53%), Gaps = 23/264 (8%)
Query: 49 PVSE--CGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTA 106
PV E CG RT RI GG +A+ G+FPWQV I + G++L W+LTA
Sbjct: 428 PVCEPVCG----LSARTTGGRIYGGQKAKPGDFPWQVLILGGTT--AAGALLYDNWVLTA 481
Query: 107 AHCLYSEELFPEELSVVLGTNDLTSPSMEIKEVASIILHKDFKR-ANMDNDIALLLLASP 165
AH +Y ++ L + +GT SP ++ +H+ + A DNDIAL+ L +
Sbjct: 482 AHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNK 541
Query: 166 IKLDDLKVPICLPTQPGPATWRECWV---AGWGQTNAADKNSVKTDLMKAPMVIMDWEEC 222
+ ++ PICLP + + R + +GWG T + + +LM + I+D ++C
Sbjct: 542 VVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ---RGFLARNLMYVDIPIVDHQKC 598
Query: 223 SKMFPK-------LTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGK- 274
+ + K +T NMLCAG ++ D+C+GDSGG LV E+W+ GI+SWG
Sbjct: 599 TAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSM 658
Query: 275 SCGEKNTPGIYTSLVNYNLWIEKV 298
+CGE G+YT ++NY WIE +
Sbjct: 659 NCGEAGQYGVYTKVINYIPWIENI 682
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 151 bits (382), Expect = 7e-37
Identities = 91/243 (37%), Positives = 133/243 (54%), Gaps = 17/243 (6%)
Query: 67 RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGT 126
R+ GG EA V +PWQVSIQ + CGGSIL+ W+LTAAHC + + V G+
Sbjct: 199 RVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHC-FRKHTDVFNWKVRAGS 257
Query: 127 NDLTS-PSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLP---TQPG 182
+ L S PS+ + ++ I + + + DNDIAL+ L P+ PICLP +
Sbjct: 258 DKLGSFPSLAVAKIIIIEFNPMYPK---DNDIALMKLQFPLTFSGTVRPICLPFFDEELT 314
Query: 183 PATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECS---KMFPKLTKNMLCAGYK 239
PAT W+ GWG T + + L++A + ++D C+ ++T+ M+CAG
Sbjct: 315 PAT--PLWIIGWGFTK-QNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIP 371
Query: 240 NESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVT 299
D C+GDSGGPL+ ++W+ VGI+SWG CG +TPG+YT + Y WI V
Sbjct: 372 EGGVDTCQGDSGGPLM---YQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVW 428
Query: 300 QLE 302
+ E
Sbjct: 429 KAE 431
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 151 bits (382), Expect = 7e-37
Identities = 91/243 (37%), Positives = 133/243 (54%), Gaps = 17/243 (6%)
Query: 67 RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGT 126
R+ GG EA V +PWQVSIQ + CGGSIL+ W+LTAAHC + + V G+
Sbjct: 204 RVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHC-FRKHTDVFNWKVRAGS 262
Query: 127 NDLTS-PSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLP---TQPG 182
+ L S PS+ + ++ I + + + DNDIAL+ L P+ PICLP +
Sbjct: 263 DKLGSFPSLAVAKIIIIEFNPMYPK---DNDIALMKLQFPLTFSGTVRPICLPFFDEELT 319
Query: 183 PATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECS---KMFPKLTKNMLCAGYK 239
PAT W+ GWG T + + L++A + ++D C+ ++T+ M+CAG
Sbjct: 320 PAT--PLWIIGWGFTK-QNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIP 376
Query: 240 NESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVT 299
D C+GDSGGPL+ ++W+ VGI+SWG CG +TPG+YT + Y WI V
Sbjct: 377 EGGVDTCQGDSGGPLM---YQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVW 433
Query: 300 QLE 302
+ E
Sbjct: 434 KAE 436
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 151 bits (382), Expect = 7e-37
Identities = 90/241 (37%), Positives = 130/241 (53%), Gaps = 19/241 (7%)
Query: 67 RITGGMEAEVGEFPWQVSIQAR-SEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLG 125
RI GG + G +PWQ S+Q+ S CG ++ K W+LT AHC E VVLG
Sbjct: 801 RILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGREN-AAVWKVVLG 859
Query: 126 TNDLTSPS--MEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGP 183
N+L PS M+ + V +IILH + RA +D DI+++ L+ I P+CLP P
Sbjct: 860 INNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVRPVCLPN---P 916
Query: 184 ATWRE----CWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPK--LTKNMLCAG 237
W E C++ GWG N + L + + I+ E C F +T M+CAG
Sbjct: 917 EQWLEPDTYCYITGWGHMG----NKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAG 972
Query: 238 YKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNT-PGIYTSLVNYNLWIE 296
Y++ + D+C GDSGGPLVC +PG +W G+ SWG C K PG+Y+++ + WI+
Sbjct: 973 YESGTVDSCMGDSGGPLVC-EKPGGRWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVEWIK 1031
Query: 297 K 297
+
Sbjct: 1032 R 1032
>gi|169172917 PREDICTED: hypothetical protein LOC346702 [Homo
sapiens]
Length = 213
Score = 151 bits (381), Expect = 1e-36
Identities = 77/207 (37%), Positives = 124/207 (59%), Gaps = 10/207 (4%)
Query: 93 CGGSILNKWWILTAAHCLYSE--ELFPEELSVVLGTNDLTSPSMEIKEVASIILHKDFKR 150
CGGSIL+ WW+LTAAHC ++ ++VV+GT ++ E K+V +I+HKD+K
Sbjct: 7 CGGSILHWWWVLTAAHCFRRTLLDMAVVNVTVVMGTRTFSNIHSERKQVQKVIIHKDYKP 66
Query: 151 ANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECWVAGWGQTNAADK-NSVKTDL 209
+D+D++LLLLA+P++ + K+P+CL Q TW CW+A W TN D+ + + L
Sbjct: 67 PQLDSDLSLLLLATPVQFSNFKMPVCL--QEEERTWDWCWMAQWVTTNGYDQYDDLNMHL 124
Query: 210 MKAPMVIMDWEECSKMFPKLTKNMLCAGYKN-----ESYDACKGDSGGPLVCTPEPGEKW 264
K +V + +EC+K +L++NM+CA + S+ +GDSG PLVC ++
Sbjct: 125 EKLRVVQISRKECAKRINQLSRNMICAWNEPGTNDCSSFPHSQGDSGAPLVCAIYGTQRL 184
Query: 265 YQVGIISWGKSCGEKNTPGIYTSLVNY 291
+QVG+ S G G + PG++ S+ +
Sbjct: 185 FQVGVFSGGIRSGSRGRPGMFVSVAQF 211
>gi|4503625 coagulation factor X preproprotein [Homo sapiens]
Length = 488
Score = 151 bits (381), Expect = 1e-36
Identities = 95/285 (33%), Positives = 145/285 (50%), Gaps = 10/285 (3%)
Query: 26 EAGVAILGRARGAHRPQPPHPPSPVSECGDRSIFEGRTRYSRITGGMEAEVGEFPWQ-VS 84
EA +I + A P P + + G +RI GG E + GE PWQ +
Sbjct: 193 EAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALL 252
Query: 85 IQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEIKEVASIIL 144
I +E FCGG+IL++++ILTAAHCLY + F ++ V + + EV +I
Sbjct: 253 INEENEGFCGGTILSEFYILTAAHCLYQAKRF--KVRVGDRNTEQEEGGEAVHEVEVVIK 310
Query: 145 HKDFKRANMDNDIALLLLASPIKLDDLKVPICLP----TQPGPATWRECWVAGWGQTNAA 200
H F + D DIA+L L +PI P CLP + T + V+G+G+T+
Sbjct: 311 HNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEK 370
Query: 201 DKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKNESYDACKGDSGGPLVCTPEP 260
+ S + +++ P V + + S F +T+NM CAGY + DAC+GDSGGP V +
Sbjct: 371 GRQSTRLKMLEVPYVDRNSCKLSSSF-IITQNMFCAGYDTKQEDACQGDSGGPHVTRFK- 428
Query: 261 GEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQLEGRP 305
+ ++ GI+SWG+ C K GIYT + + WI++ + G P
Sbjct: 429 -DTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLP 472
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 150 bits (379), Expect = 2e-36
Identities = 85/249 (34%), Positives = 132/249 (53%), Gaps = 15/249 (6%)
Query: 63 TRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSV 122
+R SRI GG A G +PWQVS+ ++ CGGSI+ WI+TAAHC+ P +
Sbjct: 288 SRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTA 347
Query: 123 VLGTNDLTSPSMEI---KEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPT 179
G L M +V +I H ++ +NDIAL+ L P+ +DL P+CLP
Sbjct: 348 FAGI--LRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLP- 404
Query: 180 QPGPATWRE--CWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMF---PKLTKNML 234
PG E CW++GWG T +K L A +++++ + C+ + +T M+
Sbjct: 405 NPGMMLQPEQLCWISGWGATE--EKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMI 462
Query: 235 CAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLW 294
CAG+ + D+C+GDSGGPLV + W+ +G SWG C + PG+Y +++ + W
Sbjct: 463 CAGFLQGNVDSCQGDSGGPLVTS--KNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDW 520
Query: 295 IEKVTQLEG 303
I + + +G
Sbjct: 521 IYRQMRADG 529
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 150 bits (379), Expect = 2e-36
Identities = 85/249 (34%), Positives = 132/249 (53%), Gaps = 15/249 (6%)
Query: 63 TRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSV 122
+R SRI GG A G +PWQVS+ ++ CGGSI+ WI+TAAHC+ P +
Sbjct: 251 SRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTA 310
Query: 123 VLGTNDLTSPSMEI---KEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPT 179
G L M +V +I H ++ +NDIAL+ L P+ +DL P+CLP
Sbjct: 311 FAGI--LRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLP- 367
Query: 180 QPGPATWRE--CWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMF---PKLTKNML 234
PG E CW++GWG T +K L A +++++ + C+ + +T M+
Sbjct: 368 NPGMMLQPEQLCWISGWGATE--EKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMI 425
Query: 235 CAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLW 294
CAG+ + D+C+GDSGGPLV + W+ +G SWG C + PG+Y +++ + W
Sbjct: 426 CAGFLQGNVDSCQGDSGGPLVTS--KNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDW 483
Query: 295 IEKVTQLEG 303
I + + +G
Sbjct: 484 IYRQMRADG 492
>gi|10518503 coagulation factor VII isoform b precursor [Homo
sapiens]
Length = 444
Score = 149 bits (376), Expect = 4e-36
Identities = 95/274 (34%), Positives = 139/274 (50%), Gaps = 20/274 (7%)
Query: 47 PSPVSECGDRSIFEGRTR---YSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWI 103
P+ CG I E R RI GG GE PWQV + CGG+++N W+
Sbjct: 167 PTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWV 226
Query: 104 LTAAHCLYSEELFPEELSVVLGTNDLT--SPSMEIKEVASIILHKDFKRANMDNDIALLL 161
++AAHC + + L VLG +DL+ + + VA +I+ + ++DIALL
Sbjct: 227 VSAAHCFDKIKNW-RNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLR 285
Query: 162 LASPIKLDDLKVPICLP----TQPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIM 217
L P+ L D VP+CLP ++ A R V+GWGQ D+ + +LM + +
Sbjct: 286 LHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQ--LLDRGATALELMVLNVPRL 343
Query: 218 DWEECSKM------FPKLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIIS 271
++C + P +T+ M CAGY + S D+CKGDSGGP T G WY GI+S
Sbjct: 344 MTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGP-HATHYRG-TWYLTGIVS 401
Query: 272 WGKSCGEKNTPGIYTSLVNYNLWIEKVTQLEGRP 305
WG+ C G+YT + Y W++K+ + E RP
Sbjct: 402 WGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRP 435
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,754,337
Number of Sequences: 37866
Number of extensions: 873488
Number of successful extensions: 4093
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 3353
Number of HSP's gapped (non-prelim): 228
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.