Guide to the Human Genome
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Name: TPSG1 Sequence: fasta or formatted (321aa) NCBI GI: 156938340
Description:

transmembrane tryptase preproprotein

Referenced in:

Neutrophils, Eosinophils, and Basophils
Serine Proteases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.2         23           2
 C cysteine            4.4         14           1
 D aspartate           4.0         13           2
 E glutamate           3.1         10           1
 F phenylalanine       2.2          7           2
 G glycine            12.5         40           2
 H histidine           2.5          8           1
 I isoleucine          3.4         11           2
 K lysine              0.6          2           1
 L leucine            12.5         40           5
 M methionine          0.6          2           1
 N asparagine          1.2          4           1
 P proline            10.0         32           3
 Q glutamine           3.4         11           1
 R arginine            6.2         20           2
 S serine              9.0         29           2
 T threonine           4.0         13           1
 V valine              8.4         27           2
 W tryptophan          2.5          8           1
 Y tyrosine            2.2          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transmembrane tryptase preproprotein 
TPSB2                 0.323   tryptase beta 2 precursor 
PRSS27                0.321   marapsin 
TPSAB1                0.320   tryptase alpha/beta 1 precursor 
PRSS33                0.309   protease, serine, 33 
PRSS21                0.307   testisin isoform 2 
PRSS21                0.304   testisin isoform 1 
TESSP1                0.301   testis-specific serine protease 1 
PRSS8                 0.300   prostasin preproprotein 
PRSS22                0.296   protease, serine, 22 
PRSS36                0.296   protease, serine, 36 
PRSS21                0.281   testisin isoform 3 
TMPRSS13              0.269   transmembrane protease, serine 13 
TMPRSS6               0.264   transmembrane protease, serine 6 
KLKB1                 0.260   plasma kallikrein B1 precursor 
PLG                   0.253   plasminogen 
ESSPL                 0.247   epidermis-specific serine protease-like protein [Ho...
MPN2                  0.246   marapsin 2 
TMPRSS4               0.241   transmembrane protease, serine 4 isoform 3 
TMPRSS4               0.241   transmembrane protease, serine 4 isoform 1 
TMPRSS11D             0.240   transmembrane protease, serine 11D 
TMPRSS3               0.240   transmembrane protease, serine 3 isoform 1 
ACR                   0.240   acrosin precursor 
TMPRSS11B             0.238   transmembrane protease, serine 11B 
TMPRSS2               0.238   transmembrane protease, serine 2 isoform 1 
TMPRSS2               0.238   transmembrane protease, serine 2 isoform 2 
TMPRSS5               0.238   transmembrane protease, serine 5 
TMPRSS7               0.235   transmembrane protease, serine 7 
LPA                   0.233   lipoprotein Lp(a) precursor 
TPSD1                 0.232   tryptase delta 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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