Guide to the Human Genome
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Search of human proteins with 166795252

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166795252 hypothetical protein LOC23359 [Homo sapiens]
         (539 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166795252 hypothetical protein LOC23359 [Homo sapiens]            1090   0.0  
gi|38146116 hypothetical protein LOC10712 isoform a [Homo sapiens]    262   5e-70
gi|189027139 chromosome 9 open reading frame 61 [Homo sapiens]        185   8e-47
gi|189027135 chromosome 9 open reading frame 61 [Homo sapiens]        185   8e-47
gi|38146118 hypothetical protein LOC10712 isoform b [Homo sapiens]    130   3e-30
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              53   6e-07
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]          52   2e-06
gi|57863314 vacuolar protein sorting 37C [Homo sapiens]                50   5e-06
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         50   7e-06
gi|55750053 atrophin-1 [Homo sapiens]                                  49   1e-05
gi|55750041 atrophin-1 [Homo sapiens]                                  49   1e-05
gi|16933561 sarcospan isoform 1 [Homo sapiens]                         49   2e-05
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               49   2e-05
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap...    48   3e-05
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap...    48   3e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    48   3e-05
gi|223972704 hypothetical protein LOC284418 [Homo sapiens]             47   3e-05
gi|146134388 YLP motif containing 1 [Homo sapiens]                     47   3e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    47   4e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    47   4e-05
gi|4809279 annexin VII isoform 2 [Homo sapiens]                        47   4e-05
gi|4502111 annexin VII isoform 1 [Homo sapiens]                        47   4e-05
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    47   6e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   6e-05
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    46   8e-05
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             46   8e-05
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       46   8e-05
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    46   8e-05
gi|238908524 hypothetical protein LOC389333 [Homo sapiens]             46   1e-04
gi|150170670 piccolo isoform 2 [Homo sapiens]                          46   1e-04

>gi|166795252 hypothetical protein LOC23359 [Homo sapiens]
          Length = 539

 Score = 1090 bits (2818), Expect = 0.0
 Identities = 539/539 (100%), Positives = 539/539 (100%)

Query: 1   MPPAGGPRAPRPAALPRSLSRLRECPGRSRIVLALGATQMALGCLIVAVSFAALALTTSA 60
           MPPAGGPRAPRPAALPRSLSRLRECPGRSRIVLALGATQMALGCLIVAVSFAALALTTSA
Sbjct: 1   MPPAGGPRAPRPAALPRSLSRLRECPGRSRIVLALGATQMALGCLIVAVSFAALALTTSA 60

Query: 61  RVRHSCPFWAGFSVLLSGLIGVVSWKRPLSLVITFFMLLSAVCVMLNLAGSILSCQNAQL 120
           RVRHSCPFWAGFSVLLSGLIGVVSWKRPLSLVITFFMLLSAVCVMLNLAGSILSCQNAQL
Sbjct: 61  RVRHSCPFWAGFSVLLSGLIGVVSWKRPLSLVITFFMLLSAVCVMLNLAGSILSCQNAQL 120

Query: 121 VNSLEGCQLIKFDSVEVCVCCELQHQSSGCSNLGETLKLNPLQENCNAVRLTLKDLLFSV 180
           VNSLEGCQLIKFDSVEVCVCCELQHQSSGCSNLGETLKLNPLQENCNAVRLTLKDLLFSV
Sbjct: 121 VNSLEGCQLIKFDSVEVCVCCELQHQSSGCSNLGETLKLNPLQENCNAVRLTLKDLLFSV 180

Query: 181 CALNVLSTIVCALATAMCCMQMVSSDVLQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEF 240
           CALNVLSTIVCALATAMCCMQMVSSDVLQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEF
Sbjct: 181 CALNVLSTIVCALATAMCCMQMVSSDVLQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEF 240

Query: 241 IPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEA 300
           IPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEA
Sbjct: 241 IPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEA 300

Query: 301 VVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGP 360
           VVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGP
Sbjct: 301 VVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGP 360

Query: 361 VGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCS 420
           VGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCS
Sbjct: 361 VGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCS 420

Query: 421 QDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPATSKERPRSL 480
           QDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPATSKERPRSL
Sbjct: 421 QDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPATSKERPRSL 480

Query: 481 VDSKAYADARVLVAKFLEHSHCALPTEAQHMVGAMRLAVTNEERLEEEAVFGADVLDQV 539
           VDSKAYADARVLVAKFLEHSHCALPTEAQHMVGAMRLAVTNEERLEEEAVFGADVLDQV
Sbjct: 481 VDSKAYADARVLVAKFLEHSHCALPTEAQHMVGAMRLAVTNEERLEEEAVFGADVLDQV 539


>gi|38146116 hypothetical protein LOC10712 isoform a [Homo sapiens]
          Length = 668

 Score =  262 bits (670), Expect = 5e-70
 Identities = 149/361 (41%), Positives = 206/361 (57%), Gaps = 24/361 (6%)

Query: 3   PAGGPRAPRPAALPRSLSRLRECPGRSRIVLALGATQMALGCLIVAVSFAALALTTSARV 62
           P+   R+       R L+ LR      + +L LG  Q+ LG L+V  S  A ++TT+  +
Sbjct: 5   PSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESI 64

Query: 63  RHSCPFWAGFSVLLSGLIGVVSWKRPLSLVITFFMLLSAVCVMLNLAGSILSCQNAQLVN 122
           + SCP WAGFS+  SG++G+VSWKRP +LVI+FF LLS +CVML++AGS+LSC+NAQL  
Sbjct: 65  KRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNAQLAR 124

Query: 123 SLEGCQLIKFDSVEVCVCCELQHQSSGCSNLGETLKLNPLQENCNAVRLTLKDLLFSVCA 182
             + C L      +VCVCC        C   G+ LK+ P    C+  R  LK+LLFSVC 
Sbjct: 125 DFQQCSL----EGKVCVCCPSVPLLRPCPESGQELKVAP-NSTCDEARGALKNLLFSVCG 179

Query: 183 LNVLSTIVCALATAMCCMQMVSSDVLQMFLPQR--SHPANPTCVT--PHGTVLHQTLDFD 238
           L + + I+C L+  +CC+Q+ S D++    P+R  S P  P   T  P   +LH  LD +
Sbjct: 180 LTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPLLHTMLDLE 239

Query: 239 EFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPY 298
           EF+PP+PPPPYYPPEYTC+  T+AQ               Y+ +++SP  LYP + PP Y
Sbjct: 240 EFVPPVPPPPYYPPEYTCSSETDAQ------------SITYNGSMDSPVPLYPTDCPPSY 287

Query: 299 EAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSE-GTATPGSSPSP 357
           EAV+G    SQ T    Q+ + S      ++     V  DS SL++S  G    GSSPS 
Sbjct: 288 EAVMGLRGDSQATLFDPQLHDGSCICERVAS--IVDVSMDSGSLVLSAIGDLPGGSSPSE 345

Query: 358 D 358
           D
Sbjct: 346 D 346



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 50/168 (29%), Positives = 70/168 (41%), Gaps = 20/168 (11%)

Query: 344 VSEGTATPGSSPSPDGPVGAPAPSEPAL-PPGHVSPEDPGMGSQVQPGPGRVSRSTSDPT 402
           V  G   P ++P    P    + S  +L PPGH  P          P P  + RS SDP 
Sbjct: 443 VPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHP------ASPPPLLLPRSHSDPG 496

Query: 403 LCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKT-- 460
           + TSS   D +  R   ++ LE    EA   S++ +   + AC  +L+    P   +   
Sbjct: 497 ITTSS---DTADFRDLYTKVLE---EEAASVSSADTGLCSEACLFRLARCPSPKLLRARS 550

Query: 461 --DQRPTP--EPFPATSKERP-RSLVDSKAYADARVLVAKFLEHSHCA 503
              +RP P  +  P  S   P  SL D K     R LV +FL+ S  A
Sbjct: 551 AEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKA 598


>gi|189027139 chromosome 9 open reading frame 61 [Homo sapiens]
          Length = 450

 Score =  185 bits (470), Expect = 8e-47
 Identities = 144/456 (31%), Positives = 209/456 (45%), Gaps = 81/456 (17%)

Query: 91  LVITFFMLLSAVCVMLNLAGSILSCQNAQLVNSLEGCQLIKFDSVEVCVCCELQHQSSGC 150
           L++  F+LLS VCV+LNLAG IL CQ AQ V+S+  C L+     ++C CCE + Q + C
Sbjct: 3   LLVNLFVLLSVVCVLLNLAGFILGCQGAQFVSSVPRCDLVDLGEGKICFCCE-EFQPAKC 61

Query: 151 SNLGETLKLNPLQENCNAVRLTLKDLLFSVCALNVLSTIVCALATAMCCMQMVSSDVLQM 210
           ++    LKL P+Q  C+AV L LK +LF++CALN L+T VC +A A+          LQ+
Sbjct: 62  TDKENALKLFPVQP-CSAVHLLLKKVLFALCALNALTTTVCLVAAAL--------RYLQI 112

Query: 211 FLPQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDF 270
           F  +RS                +  D D+F+PP+PPP Y+   Y+CTP    +R +  D 
Sbjct: 113 FATRRSCIDESQISAEEAEDHGRIPDPDDFVPPVPPPSYFATFYSCTPRMN-RRMVGPDV 171

Query: 271 APSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAG 330
            P P   +Y   I    +  P + PPPYEAVV Q    Q +S   Q++E S         
Sbjct: 172 IPLPH--IYGARIKGVEVFCPLDPPPPYEAVVSQMDQEQGSSF--QMSEGSE-------- 219

Query: 331 FSTPVPADSTSLLVSEGTATP-------GSSPSPDGPVGAPAPSEPALPPGHVSPEDPGM 383
            +  +P D     V++    P        S+ +P   +  P  S  ALPP          
Sbjct: 220 -AAVIPLDLGCTQVTQDGDIPNIPAEENASTSTPSSTLVRPIRSRRALPPLR-------- 270

Query: 384 GSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATA 443
                      +RS SDP L         S  R +     EA    A      +  +A  
Sbjct: 271 -----------TRSKSDPVL-------HPSEERAAPVLSCEA----ATQTERRLDLAAVT 308

Query: 444 ACRAQLSPAGDPDTWKTDQRPTPEPFPATSKERPRSLVDSKAYADARVLVAKFLEHSHCA 503
             R   S A                    S+ RPRSL+D K+Y D ++LVA+FLE S C 
Sbjct: 309 LRRGLRSRA--------------------SRCRPRSLIDYKSYMDTKLLVARFLEQSSCT 348

Query: 504 LPTEAQHMVGAMRLAVTNEERLEEEAVFGADVLDQV 539
           +  +   +V  ++  + ++E   EEA+  A  L+Q+
Sbjct: 349 MTPDIHELVENIKSVLKSDEEHMEEAITSASFLEQI 384


>gi|189027135 chromosome 9 open reading frame 61 [Homo sapiens]
          Length = 450

 Score =  185 bits (470), Expect = 8e-47
 Identities = 144/456 (31%), Positives = 209/456 (45%), Gaps = 81/456 (17%)

Query: 91  LVITFFMLLSAVCVMLNLAGSILSCQNAQLVNSLEGCQLIKFDSVEVCVCCELQHQSSGC 150
           L++  F+LLS VCV+LNLAG IL CQ AQ V+S+  C L+     ++C CCE + Q + C
Sbjct: 3   LLVNLFVLLSVVCVLLNLAGFILGCQGAQFVSSVPRCDLVDLGEGKICFCCE-EFQPAKC 61

Query: 151 SNLGETLKLNPLQENCNAVRLTLKDLLFSVCALNVLSTIVCALATAMCCMQMVSSDVLQM 210
           ++    LKL P+Q  C+AV L LK +LF++CALN L+T VC +A A+          LQ+
Sbjct: 62  TDKENALKLFPVQP-CSAVHLLLKKVLFALCALNALTTTVCLVAAAL--------RYLQI 112

Query: 211 FLPQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDF 270
           F  +RS                +  D D+F+PP+PPP Y+   Y+CTP    +R +  D 
Sbjct: 113 FATRRSCIDESQISAEEAEDHGRIPDPDDFVPPVPPPSYFATFYSCTPRMN-RRMVGPDV 171

Query: 271 APSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAG 330
            P P   +Y   I    +  P + PPPYEAVV Q    Q +S   Q++E S         
Sbjct: 172 IPLPH--IYGARIKGVEVFCPLDPPPPYEAVVSQMDQEQGSSF--QMSEGSE-------- 219

Query: 331 FSTPVPADSTSLLVSEGTATP-------GSSPSPDGPVGAPAPSEPALPPGHVSPEDPGM 383
            +  +P D     V++    P        S+ +P   +  P  S  ALPP          
Sbjct: 220 -AAVIPLDLGCTQVTQDGDIPNIPAEENASTSTPSSTLVRPIRSRRALPPLR-------- 270

Query: 384 GSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATA 443
                      +RS SDP L         S  R +     EA    A      +  +A  
Sbjct: 271 -----------TRSKSDPVL-------HPSEERAAPVLSCEA----ATQTERRLDLAAVT 308

Query: 444 ACRAQLSPAGDPDTWKTDQRPTPEPFPATSKERPRSLVDSKAYADARVLVAKFLEHSHCA 503
             R   S A                    S+ RPRSL+D K+Y D ++LVA+FLE S C 
Sbjct: 309 LRRGLRSRA--------------------SRCRPRSLIDYKSYMDTKLLVARFLEQSSCT 348

Query: 504 LPTEAQHMVGAMRLAVTNEERLEEEAVFGADVLDQV 539
           +  +   +V  ++  + ++E   EEA+  A  L+Q+
Sbjct: 349 MTPDIHELVENIKSVLKSDEEHMEEAITSASFLEQI 384


>gi|38146118 hypothetical protein LOC10712 isoform b [Homo sapiens]
          Length = 572

 Score =  130 bits (327), Expect = 3e-30
 Identities = 76/189 (40%), Positives = 105/189 (55%), Gaps = 19/189 (10%)

Query: 175 DLLFSVCALNVLSTIVCALATAMCCMQMVSSDVLQMFLPQRS--HPANPTCVT--PHGTV 230
           +LLFSVC L + + I+C L+  +CC+Q+ S D++    P+RS   P  P   T  P   +
Sbjct: 76  NLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHTLAPERSVSGPLGPLGCTSPPPAPL 135

Query: 231 LHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLY 290
           LH  LD +EF+PP+PPPPYYPPEYTC+  T+AQ               Y+ +++SP  LY
Sbjct: 136 LHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQ------------SITYNGSMDSPVPLY 183

Query: 291 PAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSE-GTA 349
           P + PP YEAV+G    SQ T    Q+ + S      ++     V  DS SL++S  G  
Sbjct: 184 PTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICERVAS--IVDVSMDSGSLVLSAIGDL 241

Query: 350 TPGSSPSPD 358
             GSSPS D
Sbjct: 242 PGGSSPSED 250



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 29/80 (36%), Positives = 43/80 (53%)

Query: 3  PAGGPRAPRPAALPRSLSRLRECPGRSRIVLALGATQMALGCLIVAVSFAALALTTSARV 62
          P+   R+       R L+ LR      + +L LG  Q+ LG L+V  S  A ++TT+  +
Sbjct: 5  PSDSSRSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESI 64

Query: 63 RHSCPFWAGFSVLLSGLIGV 82
          + SCP WAGFS LL  + G+
Sbjct: 65 KRSCPSWAGFSNLLFSVCGL 84



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 50/168 (29%), Positives = 70/168 (41%), Gaps = 20/168 (11%)

Query: 344 VSEGTATPGSSPSPDGPVGAPAPSEPAL-PPGHVSPEDPGMGSQVQPGPGRVSRSTSDPT 402
           V  G   P ++P    P    + S  +L PPGH  P          P P  + RS SDP 
Sbjct: 347 VPRGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRPPHP------ASPPPLLLPRSHSDPG 400

Query: 403 LCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKT-- 460
           + TSS   D +  R   ++ LE    EA   S++ +   + AC  +L+    P   +   
Sbjct: 401 ITTSS---DTADFRDLYTKVLE---EEAASVSSADTGLCSEACLFRLARCPSPKLLRARS 454

Query: 461 --DQRPTP--EPFPATSKERP-RSLVDSKAYADARVLVAKFLEHSHCA 503
              +RP P  +  P  S   P  SL D K     R LV +FL+ S  A
Sbjct: 455 AEKRRPVPTFQKVPLPSGPAPAHSLGDLKGSWPGRGLVTRFLQISRKA 502


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 77/315 (24%), Positives = 113/315 (35%), Gaps = 46/315 (14%)

Query: 194 ATAMCCMQMVSSDVLQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYYPPE 253
           A A+    +V   V       +S P   T +TP        +  D+  PP PPP Y+PP 
Sbjct: 684 APALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQE--SPVISKDQSPPPSPPPSYHPPP 741

Query: 254 Y-TCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPP-PYEAVVGQ----PPA 307
             T  P    +       APS   T  +  +  P   +P   PP P E  +      PP 
Sbjct: 742 PPTKKPEVVVE-------APSASETAEE-PLQDPN--WPPPPPPAPEEQDLSMADFPPPE 791

Query: 308 SQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPS 367
               S+        SG P   +      PA S+S   +     PGS   PD P   PAP+
Sbjct: 792 EAFFSVASPEPAGPSGSPELVSS-----PAASSSSATALQIQPPGS---PDPPPAPPAPA 843

Query: 368 EPALPPGHVS--PEDPGMGSQVQPGPGRVS----------------RSTSDPTLCTSSMA 409
             +  PGHV+  P+   +G     GP R                  RS   P    +   
Sbjct: 844 PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903

Query: 410 GDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPF 469
           G ++  +P   +   +G +  VP  +S   +A       L+ +    + + +  P  EP 
Sbjct: 904 GPSAPQKP--LRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPR 961

Query: 470 PATSKERPRSLVDSK 484
           P  S     S + SK
Sbjct: 962 PPQSPASTASFIFSK 976



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 45/166 (27%), Positives = 60/166 (36%), Gaps = 23/166 (13%)

Query: 243 PLPPPPY--YPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEA 300
           P PP P   + P  +   S    R      +PS   + Y     +P L       PP   
Sbjct: 549 PCPPNPANSWVPGLSPGGSRRPPRSPERTLSPS---SGYSSQSGTPTLPPKGLAGPPASP 605

Query: 301 VVGQPPASQ-VTSIGQQVAESSSGDPNTSAGFSTPVPADST--SLLVSEGT--------- 348
              QPP  + VTS+    A  SS   +  +  S P P+D +   +L   G          
Sbjct: 606 GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPK 665

Query: 349 -----ATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQP 389
                + P S P    P  APA + PA+ PG VS  D    S   P
Sbjct: 666 VPAPFSPPPSKPRSPNP-AAPALAAPAVVPGPVSTTDASPQSPPTP 710



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 40/151 (26%), Positives = 51/151 (33%), Gaps = 39/151 (25%)

Query: 334 PVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPSE----PALPPGHVSPEDPGMGSQ--- 386
           P P   T  L   G A P      DGP+G P   E    P LP    +    G G+    
Sbjct: 498 PPPPRRTHSLHQRGLAVP------DGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCP 551

Query: 387 ----------VQPGPGR---------------VSRSTSDPTLCTSSMAGDASSHRPSCSQ 421
                     + PG  R                S  +  PTL    +AG  +S   +   
Sbjct: 552 PNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPP 611

Query: 422 DLEAGLSEAVPGSASMSRSATAACRAQLSPA 452
             E   S   PG AS+S S T+ C +   PA
Sbjct: 612 KPERVTSLRSPG-ASVSSSLTSLCSSSSDPA 641



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 49/181 (27%), Positives = 63/181 (34%), Gaps = 32/181 (17%)

Query: 320 SSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPSE--------PAL 371
           ++ G     A    P PA+S    +S G    GS   P  P    +PS         P L
Sbjct: 538 TTGGSEGAGAAPCPPNPANSWVPGLSPG----GSRRPPRSPERTLSPSSGYSSQSGTPTL 593

Query: 372 PPGHVSPEDPGMGSQVQPGPGRV--------SRSTSDPTLCTSSMAGDASSHRPSCSQDL 423
           PP  ++      G    P P RV        S S+S  +LC+SS +  A S R       
Sbjct: 594 PPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSS-SDPAPSDRSGPQILT 652

Query: 424 EAGLSEAVP----------GSASMSRSATAACRAQLSPAGDP-DTWKTDQRPTPEPFPAT 472
             G    +P             S  RS   A  A  +PA  P     TD  P   P P T
Sbjct: 653 PLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQT 712

Query: 473 S 473
           +
Sbjct: 713 T 713


>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
          Length = 845

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 58/206 (28%), Positives = 82/206 (39%), Gaps = 31/206 (15%)

Query: 293 ELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPG 352
           ++PP  EA     P +  TS   +  E S G   TS+G  T     S + L    ++TPG
Sbjct: 460 DVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPG 519

Query: 353 SSPSPDGPVGAPAPSEPALP---------PGHVSPEDPGMGSQVQPGPGRVSRSTSD-PT 402
             P  +         +PA P         PG   P  PG+G+     P   S  T+  P 
Sbjct: 520 GPPGAENSTS----HQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPE 575

Query: 403 LCTSS----MAGDASSHRPS-----CSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAG 453
             TS       G ++SH+P+      +Q  EAG S+ +P     S S         +P G
Sbjct: 576 PGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTS-----HQPTTPGG 630

Query: 454 DPDTWKTDQRPTPEPFPATSKERPRS 479
              T +T +  T +P P  SK  P S
Sbjct: 631 --GTAQTPEPGTSQPMP-LSKSTPSS 653



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 9/57 (15%)

Query: 351 PGSSPSPDG-PVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTS 406
           P  SP+ D  P  AP P+EPA PPG  SP          P P   +R+   PT   S
Sbjct: 728 PVPSPTHDPKPAEAPMPAEPA-PPGPASPGG-------APEPPAAARAGGSPTAVRS 776


>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
          Length = 355

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 47/160 (29%), Positives = 59/160 (36%), Gaps = 17/160 (10%)

Query: 242 PPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSP-GLLYPAELPPPYEA 300
           PP PPPP  P      P  E Q    L   P P    Y  + + P G      LPP    
Sbjct: 172 PPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLP--YSPSPSLPVGPTAHGALPPAPFP 229

Query: 301 VVGQP--------PASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATP- 351
           VV QP        P      +G + A   S  P  S     P P    + + + G   P 
Sbjct: 230 VVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSM---PPRPGYPGTPMGASGPGYPL 286

Query: 352 --GSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQP 389
             G +PSP  P  +P P+    PP  + P+ P    Q QP
Sbjct: 287 RGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQP 326



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 45/162 (27%), Positives = 54/162 (33%), Gaps = 29/162 (17%)

Query: 242 PPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAV 301
           PPL  PPY P  Y+ +PS       H    P+PF  +      S    Y   L P Y A 
Sbjct: 196 PPLAMPPY-PLPYSPSPSLPVGPTAHGALPPAPFPVV------SQPSFYSGPLGPTYPAA 248

Query: 302 -VGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEG-------TATPGS 353
            +G   A+  +   Q+      G P T  G S P          S G        AT G 
Sbjct: 249 QLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGK 308

Query: 354 --------------SPSPDGPVGAPAPSEPALPPGHVSPEDP 381
                          P P  P+  P P  PA P G   P  P
Sbjct: 309 PPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGP 350



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 37/129 (28%), Positives = 42/129 (32%), Gaps = 41/129 (31%)

Query: 244 LPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVVG 303
           +PP P YP     TP   +  G  L    +P          SPG  YP +   PY A  G
Sbjct: 266 MPPRPGYPG----TPMGASGPGYPLRGGRAP----------SPG--YPQQ--SPYPATGG 307

Query: 304 QPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGA 363
           +PP        Q    S  G P  S     P P                  P P  P G 
Sbjct: 308 KPPYPI-----QPQLPSFPGQPQPSVPLQPPYP------------------PGPAPPYGF 344

Query: 364 PAPSEPALP 372
           P P  PA P
Sbjct: 345 PPPPGPAWP 353


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 83/318 (26%), Positives = 110/318 (34%), Gaps = 59/318 (18%)

Query: 212  LPQRSHPANPTCVTPHGTVL----HQTLDFDEFIPPLPPPPYYP---------PEYTCTP 258
            LP  ++   PT V   G V         D    +PPL P P  P         P  T TP
Sbjct: 1291 LPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTP 1350

Query: 259  STEAQRGLHLDFAPSPFGTLY------------DVAINSPG---------LLYPAELPPP 297
                   L    AP P  TL             +V+ ++PG         L  P+ LP P
Sbjct: 1351 GRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGP 1410

Query: 298  YEAVVGQPPASQVTS-IGQQVAESSSGDPNTSAGFSTPVPAD-------STSLLVS-EGT 348
              + +  P +S + S +   V+   S     S   + P PA        S  L VS  G 
Sbjct: 1411 ASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGP 1470

Query: 349  ATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTL----C 404
            A   S   P  PV   AP  P+L P   SP    +   +   P   S  T    L     
Sbjct: 1471 ALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPT 1530

Query: 405  TSSMAGDASSHRPSCSQDLEAGLSEA---------VPGSASM---SRSATAACRAQLSPA 452
            +S + G  S+  P+CS  L    + A          P  AS+   + SA+ A    L+P 
Sbjct: 1531 SSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPM 1590

Query: 453  GDPDTWKTDQRPTPEPFP 470
              P T      P P   P
Sbjct: 1591 AAPQTAILAPSPAPPLAP 1608



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 72/268 (26%), Positives = 97/268 (36%), Gaps = 36/268 (13%)

Query: 216  SHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPF 275
            S PA  T VTP              +P  P PP   P    +PS  A   L L  APS  
Sbjct: 1468 SGPALLTSVTP---------PLAPVVPAAPGPPSLAPS-GASPSASALT-LGLATAPSLS 1516

Query: 276  GTLYDVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPV 335
             +       +PG  +P  L P    V G             V  S+   P  SA    P 
Sbjct: 1517 SS------QTPG--HPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSA----PN 1564

Query: 336  PADSTSLLVSEGTATPGSSPSPDGPVGAP-----APS-EPALPPGHVSPEDPG----MGS 385
            PA + + L++  ++   +  +P  P+ AP     APS  P L P  V    PG    + S
Sbjct: 1565 PAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLAS 1624

Query: 386  QVQPGPGRVSRSTSDPTLCTSS-MAGDASSHRPSCSQD-LEAGLSEAVPGSASMSRSATA 443
               P P     ST   +L ++S +        PS +Q  L A +   +P  AS    A A
Sbjct: 1625 SQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALA 1684

Query: 444  ACRAQLSPAGDPDTWKTDQRPTPE-PFP 470
               A       P    +     P+ PFP
Sbjct: 1685 PALAPTLGGSSPSQTLSLGTGNPQGPFP 1712



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 39/132 (29%), Positives = 47/132 (35%), Gaps = 16/132 (12%)

Query: 242  PPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAV 301
            PPL P    PP     P  +   G      PSP G L        G   P   P P  ++
Sbjct: 1058 PPLIPASR-PPGPVLLPPLQPNSGSLPQVLPSPLGVL-------SGTSRP---PTPTLSL 1106

Query: 302  VGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPV 361
               PPA    S       SS   P T     T  PA +T+   +  TAT  + P+P    
Sbjct: 1107 KPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAP---- 1162

Query: 362  GAPAPSEPALPP 373
              PAP    L P
Sbjct: 1163 -TPAPQRLILSP 1173


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 80/286 (27%), Positives = 108/286 (37%), Gaps = 56/286 (19%)

Query: 245 PPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQ 304
           PPP  +P       S  A       +A SP  +L  +    PG   PA LPPP+  V   
Sbjct: 510 PPPGAFPHPLEGGSSHHAH-----PYAMSP--SLGSLRPYPPG---PAHLPPPHSQV--- 556

Query: 305 PPASQVTSIGQQVAESSSGDPNTSAGFST------------------PVPADSTS-LLVS 345
              SQ    G  V+ SS+   +TS G                     PVP  +TS   +S
Sbjct: 557 -SYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLS 615

Query: 346 EGTATPGSSP------SPDGP--VGAPAPS----EPALPPGHVSPEDPGMGSQVQPGPGR 393
              AT  SSP      SP GP   G  APS    + A PPG+     P   +   PG   
Sbjct: 616 TVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPG--- 672

Query: 394 VSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGL-SEAVPGSASMSRSATAACRAQLSPA 452
             R TS P    +   G  +           +GL S   P +A  S    +A + +  PA
Sbjct: 673 -YRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPA 731

Query: 453 GDPDTWKTDQRPTPEPFPATSKERPRSLVDSKAYADARVLVAKFLE 498
              + ++T + P P   PA S   P  +VD  ++A       K L+
Sbjct: 732 ---EEYETPESPVP---PARSPSPPPKVVDVPSHASQSARFNKHLD 771



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 65/247 (26%), Positives = 86/247 (34%), Gaps = 52/247 (21%)

Query: 243 PLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPG---LLYPAELPPPYE 299
           P  PPP +PP      ST  Q     +  PS   T Y   +  P       P   PPP+ 
Sbjct: 158 PYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP 217

Query: 300 --------AVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATP 351
                    V+  PP           A SS G PN   G   P P    S+  S  +  P
Sbjct: 218 QLYPGGTGGVLSGPPMGPKGG----GAASSVGGPN--GGKQHPPPTTPISVSSSGASGAP 271

Query: 352 GSSPSPDGPVG------APAPSE-----PALPP-------GHVSPEDPGMGSQVQPG--- 390
            + P P  PVG      AP P+      P LPP        + S   PG+G+Q  PG   
Sbjct: 272 PTKP-PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLP 330

Query: 391 -------------PGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASM 437
                        PG     T  P+  +   A  ++   P       +  S A   S+S 
Sbjct: 331 SPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390

Query: 438 SRSATAA 444
           S S++A+
Sbjct: 391 SSSSSAS 397



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 46/189 (24%), Positives = 65/189 (34%), Gaps = 22/189 (11%)

Query: 236 DFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLD-FAPSP------FGTLYDVAINSPGL 288
           +F    P LPPPP   P    + S        L    PSP       G L       P L
Sbjct: 293 NFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTL 352

Query: 289 LYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGT 348
                  PP  +    PP     S     + ++S   ++S+  ++P PA           
Sbjct: 353 APSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF 412

Query: 349 ATPGSSPSPDGPVGAPAPSEPALPPGHV----SPEDPGMG-----SQVQPG---PGRVSR 396
             P S    + P   P  ++P+LP   V     P  P  G     S   PG   P   ++
Sbjct: 413 PPPTSLSVSNQP---PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ 469

Query: 397 STSDPTLCT 405
           ST+ P + T
Sbjct: 470 STAHPPVST 478


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 80/286 (27%), Positives = 108/286 (37%), Gaps = 56/286 (19%)

Query: 245 PPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQ 304
           PPP  +P       S  A       +A SP  +L  +    PG   PA LPPP+  V   
Sbjct: 510 PPPGAFPHPLEGGSSHHAH-----PYAMSP--SLGSLRPYPPG---PAHLPPPHSQV--- 556

Query: 305 PPASQVTSIGQQVAESSSGDPNTSAGFST------------------PVPADSTS-LLVS 345
              SQ    G  V+ SS+   +TS G                     PVP  +TS   +S
Sbjct: 557 -SYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLS 615

Query: 346 EGTATPGSSP------SPDGP--VGAPAPS----EPALPPGHVSPEDPGMGSQVQPGPGR 393
              AT  SSP      SP GP   G  APS    + A PPG+     P   +   PG   
Sbjct: 616 TVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPG--- 672

Query: 394 VSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGL-SEAVPGSASMSRSATAACRAQLSPA 452
             R TS P    +   G  +           +GL S   P +A  S    +A + +  PA
Sbjct: 673 -YRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPA 731

Query: 453 GDPDTWKTDQRPTPEPFPATSKERPRSLVDSKAYADARVLVAKFLE 498
              + ++T + P P   PA S   P  +VD  ++A       K L+
Sbjct: 732 ---EEYETPESPVP---PARSPSPPPKVVDVPSHASQSARFNKHLD 771



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 65/247 (26%), Positives = 86/247 (34%), Gaps = 52/247 (21%)

Query: 243 PLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPG---LLYPAELPPPYE 299
           P  PPP +PP      ST  Q     +  PS   T Y   +  P       P   PPP+ 
Sbjct: 158 PYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP 217

Query: 300 --------AVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATP 351
                    V+  PP           A SS G PN   G   P P    S+  S  +  P
Sbjct: 218 QLYPGGTGGVLSGPPMGPKGG----GAASSVGGPN--GGKQHPPPTTPISVSSSGASGAP 271

Query: 352 GSSPSPDGPVG------APAPSE-----PALPP-------GHVSPEDPGMGSQVQPG--- 390
            + P P  PVG      AP P+      P LPP        + S   PG+G+Q  PG   
Sbjct: 272 PTKP-PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLP 330

Query: 391 -------------PGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASM 437
                        PG     T  P+  +   A  ++   P       +  S A   S+S 
Sbjct: 331 SPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390

Query: 438 SRSATAA 444
           S S++A+
Sbjct: 391 SSSSSAS 397



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 46/189 (24%), Positives = 65/189 (34%), Gaps = 22/189 (11%)

Query: 236 DFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLD-FAPSP------FGTLYDVAINSPGL 288
           +F    P LPPPP   P    + S        L    PSP       G L       P L
Sbjct: 293 NFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTL 352

Query: 289 LYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGT 348
                  PP  +    PP     S     + ++S   ++S+  ++P PA           
Sbjct: 353 APSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF 412

Query: 349 ATPGSSPSPDGPVGAPAPSEPALPPGHV----SPEDPGMG-----SQVQPG---PGRVSR 396
             P S    + P   P  ++P+LP   V     P  P  G     S   PG   P   ++
Sbjct: 413 PPPTSLSVSNQP---PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ 469

Query: 397 STSDPTLCT 405
           ST+ P + T
Sbjct: 470 STAHPPVST 478


>gi|16933561 sarcospan isoform 1 [Homo sapiens]
          Length = 243

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 57/198 (28%), Positives = 83/198 (41%), Gaps = 16/198 (8%)

Query: 1   MPPAGGPRAPRPAALPRSLSRLRECPGRSRIVLALGATQMALGCLIVAVSFAALALTTSA 60
           M P  G  AP+           R C G  R  L L   Q+ALG  +  V F   ++++S 
Sbjct: 27  MEPKKGTGAPKECGEEEP----RTCCG-CRFPLLLALLQLALGIAVTVVGFLMASISSSL 81

Query: 61  RVRHSCPFWAGFSVLLSGLIGV----VSWKRPLSLVITFFMLLSAVCVMLNLAGSILSCQ 116
            VR + PFWAG  V L   +G+    VS++      I F M L  +  +L+  G +  C 
Sbjct: 82  LVRDT-PFWAGIIVCLVAYLGLFMLCVSYQVDERTCIQFSMKL--LYFLLSALG-LTVCV 137

Query: 117 NAQLVNSLEGCQLIKFDSVEVCVCCELQHQSSGCSNLGETLKLNPLQENCNAVRLTLKDL 176
            A    +    QL +F        C+ +  SS    L  T     + + C +V  T K  
Sbjct: 138 LAVAFAAHHYSQLTQFTCETTLDSCQCKLPSS--EPLSRTFVYRDVTD-CTSVTGTFKLF 194

Query: 177 LFSVCALNVLSTIVCALA 194
           L     LN++  +VC LA
Sbjct: 195 LLIQMILNLVCGLVCLLA 212


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 68/264 (25%), Positives = 95/264 (35%), Gaps = 56/264 (21%)

Query: 252 PEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPP---PYEAVVGQPPAS 308
           PE   +    A+ G  L   PSP   L+ VA+ SP    P   PP   P     G+P   
Sbjct: 200 PEACSSAERRARAGPFL--TPSP---LHAVAMRSPR---PCGRPPTDSPDAGGAGRPLDG 251

Query: 309 QVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLV-------SEGTATPGSSPSPDGPV 361
            ++++ ++     +G P TS G +   P    S+         S G+A P   PS +   
Sbjct: 252 YISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVG 311

Query: 362 GAP-----------------APSEPALPPGHVSPED-------------PGMGSQVQPGP 391
           G P                 A  EPA PP   SP D             PG  +  +  P
Sbjct: 312 GHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLP 371

Query: 392 GRVSRSTSDPTLCTSSMAGDASSHRPSCS----QDLEAGLSEAVPGSASMSRSATAAC-- 445
           GR +R    P     S+       RP  +    +  EA      P +   SRS +     
Sbjct: 372 GRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLL 431

Query: 446 -RAQLSPAGDPDTWKTDQRPTPEP 468
            RA   P+G P  + T +R  P P
Sbjct: 432 GRASAVPSG-PPKYPTAEREEPRP 454


>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
           sapiens]
          Length = 1038

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 59/221 (26%), Positives = 72/221 (32%), Gaps = 43/221 (19%)

Query: 191 CALATAMCCMQMVSSDVLQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYY 250
           CA + A   M   S       L   + P +PT   P    LH T   D    PLPPPP Y
Sbjct: 585 CAPSLAQLAMDACS-------LLDETPPQSPTRALPRP--LHPTPVVDWDARPLPPPPAY 635

Query: 251 PP------EYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVV-- 302
                   ++          G  +   PS   T Y            A  PPP E  +  
Sbjct: 636 DDVAQDEDDFEICSINSTLVGAGVPAGPSQGQTNYAFVPEQ------ARPPPPLEDNLFL 689

Query: 303 -----GQPPAS-QVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPS 356
                G+PP+S Q   I Q + +         AG   P P+             PG    
Sbjct: 690 PPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPS-------------PGGDDK 736

Query: 357 PDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQ-PGPGRVSR 396
           P  P   P P  P  P   +SP  PG     Q PGP    R
Sbjct: 737 PQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPR 777


>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
           sapiens]
          Length = 1086

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 59/221 (26%), Positives = 72/221 (32%), Gaps = 43/221 (19%)

Query: 191 CALATAMCCMQMVSSDVLQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYY 250
           CA + A   M   S       L   + P +PT   P    LH T   D    PLPPPP Y
Sbjct: 663 CAPSLAQLAMDACS-------LLDETPPQSPTRALPRP--LHPTPVVDWDARPLPPPPAY 713

Query: 251 PP------EYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVV-- 302
                   ++          G  +   PS   T Y            A  PPP E  +  
Sbjct: 714 DDVAQDEDDFEICSINSTLVGAGVPAGPSQGQTNYAFVPEQ------ARPPPPLEDNLFL 767

Query: 303 -----GQPPAS-QVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPS 356
                G+PP+S Q   I Q + +         AG   P P+             PG    
Sbjct: 768 PPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPS-------------PGGDDK 814

Query: 357 PDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQ-PGPGRVSR 396
           P  P   P P  P  P   +SP  PG     Q PGP    R
Sbjct: 815 PQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPR 855


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 44/151 (29%), Positives = 54/151 (35%), Gaps = 18/151 (11%)

Query: 242 PPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAV 301
           PP  PPP  PP +   P  +  +       P P  +   V    PG         P   V
Sbjct: 73  PPQQPPPQQPPPHQPPPHPQPHQ--QQQPPPPPQDSSKPVVAQGPG---------PAPGV 121

Query: 302 VGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPV 361
              PPAS   S        +SG P  S    TP P  + +   +   A P + PS   P 
Sbjct: 122 GSAPPAS---SSAPPATPPTSGAPPGSGPGPTPTPPPAVTS--APPGAPPPTPPSSGVPT 176

Query: 362 GAPAPSEPALPPGHVSPEDPGMGSQVQPGPG 392
             P    P  PP  V    PG G +  PGPG
Sbjct: 177 TPPQAGGPPPPPAAVP--GPGPGPKQGPGPG 205



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 41/150 (27%), Positives = 54/150 (36%), Gaps = 31/150 (20%)

Query: 242 PPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAV 301
           PP+PPPP +  +    P             P P           P    P   P P++  
Sbjct: 58  PPIPPPPPHQQQQQPPPQQ-----------PPP---------QQPPPHQPPPHPQPHQQQ 97

Query: 302 VGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGT--ATPGSSPSPDG 359
             QPP     S    VA+     P  + G  +  PA S++   +  T  A PGS P   G
Sbjct: 98  --QPPPPPQDSSKPVVAQG----PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGP---G 148

Query: 360 PVGAPAPSEPALPPGHVSPEDPGMGSQVQP 389
           P   P P+  + PPG   P  P  G    P
Sbjct: 149 PTPTPPPAVTSAPPGAPPPTPPSSGVPTTP 178



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 18/111 (16%)

Query: 291 PAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTAT 350
           P + PPP +    QPP        QQ                 P P DS+  +V++G   
Sbjct: 73  PPQQPPPQQPPPHQPPPHPQPHQQQQ---------------PPPPPQDSSKPVVAQG--- 114

Query: 351 PGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDP 401
           PG +P       A + + PA PP   +P   G G    P P   S     P
Sbjct: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP 165


>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
          Length = 922

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 52/201 (25%), Positives = 81/201 (40%), Gaps = 18/201 (8%)

Query: 291 PAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVP---ADSTSLLVSEG 347
           P  L PP +A     P  +  ++     ++ +    +    + P P   A + S    + 
Sbjct: 433 PPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKA 492

Query: 348 TATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSS 407
           +A P + P    P    APS P +P   VSP  P   S + P P + +  TS PT    +
Sbjct: 493 SAVP-APPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTS-PTEYQMA 550

Query: 408 MAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTD------ 461
           ++  AS  +     D+   L   +PG A + RS +     +  P     T +TD      
Sbjct: 551 LSPPASRGKLPGDFDV---LPTGIPGRAVLERSQSG---GKPEPVVTVRTQETDVVEMTT 604

Query: 462 QRPTPE-PFPATSKERPRSLV 481
           Q  +PE PF  T KE    L+
Sbjct: 605 QAKSPESPFTVTKKESKDILI 625


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 61/204 (29%), Positives = 73/204 (35%), Gaps = 36/204 (17%)

Query: 241 IPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLY---PAELPPP 297
           +PP  PPP  PP     P+T    G+     P    T        P L     P  LPPP
Sbjct: 538 LPPSLPPPVMPP---ALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPP 594

Query: 298 YEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSP 357
             +  G PP     S+      SS+  P        P+P       +S  T  PG  P P
Sbjct: 595 SLSSAGPPPVLPPPSL------SSTAPPPV-----MPLPP------LSSATPPPG-IPPP 636

Query: 358 DGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRP 417
             P G P    P L    V P      SQV   P    R    PT  +   A   + H P
Sbjct: 637 GVPQGIP----PQLTAAPVPPASSSQSSQVPEKP----RPALLPTPVSFGSAPPTTYHPP 688

Query: 418 SCSQDLEAGLSEAVPGSASMSRSA 441
             S    AG SE V   A +S+SA
Sbjct: 689 LQS----AGPSEQVNSKAPLSKSA 708



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 70/285 (24%), Positives = 93/285 (32%), Gaps = 59/285 (20%)

Query: 245 PPPPYYPP--------------EYTCTPSTEAQRGLHLDFAPSPFGTLYDV--------- 281
           PPPP  PP                + TP+  +  G  + F       L  +         
Sbjct: 15  PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGF-MSFREQHLAQLQQLQQMHQKQMQ 73

Query: 282 AINSPGLLYPAELPPPYEAVVG-----QPP--------------ASQVTSIGQQVAESSS 322
            +  P  L P  LPPP     G     QPP                Q     Q +     
Sbjct: 74  CVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRD 133

Query: 323 GDPN------TSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHV 376
           G P        S   S PVP  S  +  S+    P   P P      P  S+P LPP   
Sbjct: 134 GPPGLVPMELESPPESPPVPPGS-YMPPSQSYMPP---PQPPPSYYPPTSSQPYLPPAQP 189

Query: 377 SP-EDPGMGSQVQPGPGRVSRSTSDPTLCTSSM----AGDASSHRPSCSQDLEAGLSEAV 431
           SP + P   S + P P   S S+S  +  + S     +  AS  RPS     ++ L    
Sbjct: 190 SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS-KSQLLAPP 248

Query: 432 PGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPATSKER 476
           P SA      T       S A +  T +    P P+P   T +E+
Sbjct: 249 PPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQ 293



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 30/110 (27%), Positives = 42/110 (38%), Gaps = 29/110 (26%)

Query: 242  PPLPPPPYYPPEYTCTPSTEA-------------------QRGLHLDFAPSPFGTLYDVA 282
            PP PPPP  PP     P T A                   ++GL+ +F           A
Sbjct: 1548 PPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSE------TAA 1601

Query: 283  INSPGLLYP----AELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTS 328
            I S  +L P    + +PPP    +G PP S+   + Q V      D +T+
Sbjct: 1602 IPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTN 1651



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 35/135 (25%), Positives = 47/135 (34%), Gaps = 46/135 (34%)

Query: 242 PPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAV 301
           PP PPP YYPP       T +Q  L                   P    P++ PP    +
Sbjct: 167 PPQPPPSYYPP-------TSSQPYL------------------PPAQPSPSQSPPSQSYL 201

Query: 302 VGQPPASQVTSIGQQ-VAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGP 360
              P  S  +S  Q  ++ S S  P++ A  S P    S S L+                
Sbjct: 202 APTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLL---------------- 245

Query: 361 VGAPAPSEPALPPGH 375
               AP  P+ PPG+
Sbjct: 246 ----APPPPSAPPGN 256



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 54/246 (21%), Positives = 76/246 (30%), Gaps = 32/246 (13%)

Query: 242 PPLPPPPYYP-------PEYTC--TPSTEAQRGLHLDFAPSPFGTLYDVAI----NSPGL 288
           PP+PPPP          P Y+   TP+  +  G  + F       L  +          +
Sbjct: 17  PPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGF-MSFREQHLAQLQQLQQMHQKQMQCV 75

Query: 289 LYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGT 348
           L P  LPPP       PP   +   G        GD         P P  + S    +  
Sbjct: 76  LQPHHLPPP-----PLPPPPVMPGGGY-------GDWQPPPPPMPPPPGPALSYQKQQQY 123

Query: 349 ATPGSSPSPDGPVGA------PAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPT 402
                    DGP G         P  P +PPG   P         QP P     ++S P 
Sbjct: 124 KHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPY 183

Query: 403 LCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQ 462
           L  +  +   S    S      +  S +    + +S S +    +Q SP+         Q
Sbjct: 184 LPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQ 243

Query: 463 RPTPEP 468
              P P
Sbjct: 244 LLAPPP 249


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 66/266 (24%), Positives = 95/266 (35%), Gaps = 44/266 (16%)

Query: 213 PQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPP---PYYPPEY-----TCTPSTEAQR 264
           P  S  A P+   P+   +H  L    F PP  PP   P+ PP       + TP ++A  
Sbjct: 415 PPLSPLATPSPQAPNALAVH--LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472

Query: 265 GLH---LDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAV---VGQPPASQVTSIGQQVA 318
            L    L   PSP  +       SP    P + PPP  A    + +PP     ++     
Sbjct: 473 SLAAPPLQVPPSPPAS----PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 528

Query: 319 ESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSS-------------PSPDGPVGAPA 365
           ++    P+  A F    P   ++ L     ATP                PSP       A
Sbjct: 529 QAL---PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585

Query: 366 PSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDL-- 423
           P  P  P    S   P +   + PGP      +   TL    +AG +SS   S  ++L  
Sbjct: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS-ATSTPEELRG 644

Query: 424 -----EAGLSEAVPGSASMSRSATAA 444
                E G + + P  A ++    AA
Sbjct: 645 YDSGPEGGAAASPPPDAELAACHPAA 670



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 80/307 (26%), Positives = 101/307 (32%), Gaps = 68/307 (22%)

Query: 219 ANPTC-VTPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGT 277
           A PT   TPH + L  T      +P  PP P  PP     PS  A         PS   T
Sbjct: 317 APPTLPATPHSSSL--TCQLATPLPLAPPSPSAPPSLQTLPSPPAT-------PPSQATT 367

Query: 278 LYDVAINSPGL-----------LYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPN 326
               ++ SP L           L P   PPP       PPA  +  +  Q   S    P 
Sbjct: 368 ----SLGSPTLQATHSFLPSPPLSPLATPPPQ-----APPALALPPL--QAPPSPPASPP 416

Query: 327 TSAGFSTPVPADSTSLLVS--EGTATPGSSP---SPDGPVGAPAPSEPALPPGHVSPEDP 381
            S   +TP P    +L V   +   +P  SP   +P  P  +P  S  A PP    P   
Sbjct: 417 LSP-LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 475

Query: 382 GMGSQVQPGPGR---VSRSTSDPTLCTSSMAG---DASSHRPSCSQDLEAGLSEAV---- 431
               QV P P     +S S + P      +A      +   P     L     +A+    
Sbjct: 476 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535

Query: 432 ---PGSASMSRSAT-----------------AACRAQLSPAGDPDTWKTDQRPTPEPFPA 471
              PG A  S SA+                 AA   Q+ P+          R  P P P 
Sbjct: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 595

Query: 472 TSKERPR 478
           TS   PR
Sbjct: 596 TSVSGPR 602



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 51/187 (27%), Positives = 73/187 (39%), Gaps = 15/187 (8%)

Query: 294 LPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNT------SAGFSTPVPADSTSLLVSEG 347
           LP P  +   +PP           +E S+ +P+       SAG     PA S SL     
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA-SRSL---SS 244

Query: 348 TATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSS 407
           +ATP SSP+  GP     P  PA P     P+  G+   ++P      R  + P L   S
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPS---QPKPKGL-QALRPPQVTPPRKDAAPALGPLS 300

Query: 408 MAGDASSHRPSCSQDLEAGLSEAVPGSASMS-RSATAACRAQLSPAGDPDTWKTDQRPTP 466
            +  A+    +  Q        A P S+S++ + AT    A  SP+  P        P  
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360

Query: 467 EPFPATS 473
            P  AT+
Sbjct: 361 PPSQATT 367



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 60/223 (26%), Positives = 82/223 (36%), Gaps = 24/223 (10%)

Query: 242 PPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGL---LYPAELPPPY 298
           PP  PP    P     PS  A   L     P   G   D +++ P L   L P   PPP 
Sbjct: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP--DTSVSGPRLTLALAPGPPPPPS 616

Query: 299 EA---VVGQPP----ASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATP 351
            +    +  P     +S  TS  +++    SG P   A  S P  A+  +   +  +  P
Sbjct: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSG-PEGGAAASPPPDAELAACHPAAWSRGP 675

Query: 352 GSSPSPDGPVGAPAPSEPALPPGHVSP-----EDPGMGSQVQPGPGRVSRSTSDPTLCTS 406
               +  G  GAP P  PA  PG         E  G  S   P PG +    S  T    
Sbjct: 676 APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES-ATPAPGALDPGPSPGTSGGK 734

Query: 407 SMAG---DASSHRPSCSQ--DLEAGLSEAVPGSASMSRSATAA 444
           + AG    ASS  P  ++  +L  G  +A      +SR+   A
Sbjct: 735 AAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLA 777



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 64/246 (26%), Positives = 83/246 (33%), Gaps = 42/246 (17%)

Query: 241 IPPL---PPPPYYPP-EYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPP 296
           +PPL   P PP  PP     TPS +A   L +    +PF                   PP
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS------------------PP 443

Query: 297 PYEAVVG--QPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSS 354
           P   V     PPAS    +       S   P+ +A      P+   S  +S     P  +
Sbjct: 444 PSPPVQAPFSPPAS--PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 501

Query: 355 PSP-DGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDAS 413
           P P   P    A   P  PP   +P    + S     PG+   S S      S      +
Sbjct: 502 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS-----ASLPMSPLA 556

Query: 414 SHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQR------PTPE 467
           +  P     L A L + VP S   S +  A  R    P   PDT  +  R      P P 
Sbjct: 557 TPPPQAPPVLAAPLLQ-VPPSPPASPTLQAPRR---PPTPGPDTSVSGPRLTLALAPGPP 612

Query: 468 PFPATS 473
           P P+ S
Sbjct: 613 PPPSRS 618


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 66/266 (24%), Positives = 95/266 (35%), Gaps = 44/266 (16%)

Query: 213 PQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPP---PYYPPEY-----TCTPSTEAQR 264
           P  S  A P+   P+   +H  L    F PP  PP   P+ PP       + TP ++A  
Sbjct: 376 PPLSPLATPSPQAPNALAVH--LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433

Query: 265 GLH---LDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAV---VGQPPASQVTSIGQQVA 318
            L    L   PSP  +       SP    P + PPP  A    + +PP     ++     
Sbjct: 434 SLAAPPLQVPPSPPAS----PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 489

Query: 319 ESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSS-------------PSPDGPVGAPA 365
           ++    P+  A F    P   ++ L     ATP                PSP       A
Sbjct: 490 QAL---PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546

Query: 366 PSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDL-- 423
           P  P  P    S   P +   + PGP      +   TL    +AG +SS   S  ++L  
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS-ATSTPEELRG 605

Query: 424 -----EAGLSEAVPGSASMSRSATAA 444
                E G + + P  A ++    AA
Sbjct: 606 YDSGPEGGAAASPPPDAELAACHPAA 631



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 60/223 (26%), Positives = 82/223 (36%), Gaps = 24/223 (10%)

Query: 242 PPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGL---LYPAELPPPY 298
           PP  PP    P     PS  A   L     P   G   D +++ P L   L P   PPP 
Sbjct: 520 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP--DTSVSGPRLTLALAPGPPPPPS 577

Query: 299 EA---VVGQPP----ASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATP 351
            +    +  P     +S  TS  +++    SG P   A  S P  A+  +   +  +  P
Sbjct: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSG-PEGGAAASPPPDAELAACHPAAWSRGP 636

Query: 352 GSSPSPDGPVGAPAPSEPALPPGHVSP-----EDPGMGSQVQPGPGRVSRSTSDPTLCTS 406
               +  G  GAP P  PA  PG         E  G  S   P PG +    S  T    
Sbjct: 637 APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES-ATPAPGALDPGPSPGTSGGK 695

Query: 407 SMAG---DASSHRPSCSQ--DLEAGLSEAVPGSASMSRSATAA 444
           + AG    ASS  P  ++  +L  G  +A      +SR+   A
Sbjct: 696 AAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLA 738



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 64/246 (26%), Positives = 83/246 (33%), Gaps = 42/246 (17%)

Query: 241 IPPL---PPPPYYPP-EYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPP 296
           +PPL   P PP  PP     TPS +A   L +    +PF                   PP
Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS------------------PP 404

Query: 297 PYEAVVG--QPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSS 354
           P   V     PPAS    +       S   P+ +A      P+   S  +S     P  +
Sbjct: 405 PSPPVQAPFSPPAS--PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462

Query: 355 PSP-DGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDAS 413
           P P   P    A   P  PP   +P    + S     PG+   S S      S      +
Sbjct: 463 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS-----ASLPMSPLA 517

Query: 414 SHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQR------PTPE 467
           +  P     L A L + VP S   S +  A  R    P   PDT  +  R      P P 
Sbjct: 518 TPPPQAPPVLAAPLLQ-VPPSPPASPTLQAPRR---PPTPGPDTSVSGPRLTLALAPGPP 573

Query: 468 PFPATS 473
           P P+ S
Sbjct: 574 PPPSRS 579



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 72/283 (25%), Positives = 91/283 (32%), Gaps = 65/283 (22%)

Query: 242 PPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGL-----------LY 290
           P  PP P  PP     PS  A         PS   T    ++ SP L           L 
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPAT-------PPSQATT----SLGSPTLQATHSFLPSPPLS 348

Query: 291 PAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVS--EGT 348
           P   PPP       PPA  +  +  Q   S    P  S   +TP P    +L V   +  
Sbjct: 349 PLATPPPQ-----APPALALPPL--QAPPSPPASPPLSP-LATPSPQAPNALAVHLLQAP 400

Query: 349 ATPGSSP---SPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGR---VSRSTSDPT 402
            +P  SP   +P  P  +P  S  A PP    P       QV P P     +S S + P 
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460

Query: 403 LCTSSMAG---DASSHRPSCSQDLEAGLSEAV-------PGSASMSRSAT---------- 442
                +A      +   P     L     +A+       PG A  S SA+          
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520

Query: 443 -------AACRAQLSPAGDPDTWKTDQRPTPEPFPATSKERPR 478
                  AA   Q+ P+          R  P P P TS   PR
Sbjct: 521 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 563



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 40/135 (29%), Positives = 56/135 (41%), Gaps = 15/135 (11%)

Query: 294 LPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNT------SAGFSTPVPADSTSLLVSEG 347
           LP P  +   +PP           +E S+ +P+       SAG     PA S SL     
Sbjct: 180 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA-SRSL---SS 235

Query: 348 TATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQP--GPGRVSRSTSDPTLCT 405
           +ATP SSP+  GP     P  PA P     P+  G+ +   P   P R   + +   L +
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPS---QPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292

Query: 406 SSMAGDASSHRPSCS 420
           S +A  + S  PS S
Sbjct: 293 SPLATPSPSAPPSPS 307


>gi|4809279 annexin VII isoform 2 [Homo sapiens]
          Length = 488

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 40/110 (36%), Positives = 45/110 (40%), Gaps = 14/110 (12%)

Query: 290 YPAELPPPYEAVVGQPPASQVTSI---GQQVAESSSGDPNTSAGFSTPVPADSTSLLVSE 346
           YP   P  Y    G PPA Q +S    GQ      SG P    G    VP  S+    + 
Sbjct: 3   YPGYPPTGYPPFPGYPPAGQESSFPPSGQY--PYPSGFPPMGGGAYPQVP--SSGYPGAG 58

Query: 347 GTATPGSSPSPDGPVGAP----APSEPALPPGH---VSPEDPGMGSQVQP 389
           G   PG  P+P G  GAP    APS P +PPG    V P   G     QP
Sbjct: 59  GYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQP 108


>gi|4502111 annexin VII isoform 1 [Homo sapiens]
          Length = 466

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 40/110 (36%), Positives = 45/110 (40%), Gaps = 14/110 (12%)

Query: 290 YPAELPPPYEAVVGQPPASQVTSI---GQQVAESSSGDPNTSAGFSTPVPADSTSLLVSE 346
           YP   P  Y    G PPA Q +S    GQ      SG P    G    VP  S+    + 
Sbjct: 3   YPGYPPTGYPPFPGYPPAGQESSFPPSGQY--PYPSGFPPMGGGAYPQVP--SSGYPGAG 58

Query: 347 GTATPGSSPSPDGPVGAP----APSEPALPPGH---VSPEDPGMGSQVQP 389
           G   PG  P+P G  GAP    APS P +PPG    V P   G     QP
Sbjct: 59  GYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQP 108


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 68/239 (28%), Positives = 84/239 (35%), Gaps = 34/239 (14%)

Query: 235  LDFDEFIPPLPP---PPYYPPEYTCTPSTEAQRG--LHLDFAPSPFGTLYDVAINSPGLL 289
            L      PP  P   PP  P  Y   P    Q    LH    P P      +  +S  L 
Sbjct: 978  LQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQD--PLPAHSGALP 1035

Query: 290  YPAELPP-PYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGT 348
            +P+  PP P    +   PA     +G Q A  +   P+ SAG STP P      LV    
Sbjct: 1036 FPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPS-SAGQSTPSPH-----LVPSPA 1089

Query: 349  ATPGSSPSPDGPVGAPAPSEPALPPGHV-------SPEDPGMGSQVQPGPGRVSRSTSDP 401
             +PG  P P  P  A  P  P L  G         SPE    G+Q  PG G+        
Sbjct: 1090 PSPGPGPVPPRPPAAEPP--PCLRRGAAAADLLSSSPESQHGGTQ-SPGGGQ-------- 1138

Query: 402  TLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDT-WK 459
             L   +    A   RP   + +E    E  P      +    A R QL   G  DT W+
Sbjct: 1139 PLLQPTKVDAAEGRRPQALRLIERDPYEH-PERLRQLQQELEAFRGQLGDVGALDTVWR 1196



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 40/155 (25%), Positives = 57/155 (36%), Gaps = 19/155 (12%)

Query: 242 PPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPP----P 297
           P L P P Y PE    P +  Q G+      SP+     V    P    P+  PP    P
Sbjct: 819 PALYPAPAYTPELGLVPRSSPQHGV----VSSPY---VGVGPAPPVAGLPSAPPPQFSGP 871

Query: 298 YEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTP-VPADSTSLLVSEGTATPGSSPS 356
             A+  +P  + V SI   +   ++  PN +     P  P      L +  T   G+   
Sbjct: 872 ELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQ- 930

Query: 357 PDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGP 391
              P+ A       +P G  +P    +G Q QP P
Sbjct: 931 ---PIPAQHHFSSGIPAGFPAPR---IGPQPQPHP 959


>gi|163965366 nascent polypeptide-associated complex alpha subunit
           isoform a [Homo sapiens]
          Length = 2078

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 73/281 (25%), Positives = 98/281 (34%), Gaps = 38/281 (13%)

Query: 221 PTCVTPHGTVLH-QTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTL- 278
           P   +P  T     TL     IP   P P  PP  T  P T+   G+    A +P  +  
Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGT-PPGTKKVDGISHTSALAPVASSP 767

Query: 279 ---------YDVAINSPGLL-YPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTS 328
                         +S G L Y A+ P P    V        T  G       S  P+T 
Sbjct: 768 KECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKG-------SAGPDTP 820

Query: 329 AG-FSTPV--------PADSTSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPE 379
            G  S+PV        P +S S   S+ +     SP+P  P GAP PS  A+ P  +SP+
Sbjct: 821 IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPS--AVTP--LSPK 876

Query: 380 DPGMGSQVQPGPGRVSR--STSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASM 437
              +  +  P P  V+       P       A   S    S  +       + +P S S 
Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936

Query: 438 SRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPATSKERPR 478
             + T       SP G P T      PTP   PA +   P+
Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAPTP---PAATPPSPK 974



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 63/250 (25%), Positives = 88/250 (35%), Gaps = 26/250 (10%)

Query: 246  PPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSP--GLLYPAELPP------- 296
            PP   PP     P+T + +G     A +P       A  SP      PA  PP       
Sbjct: 965  PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024

Query: 297  --PYEAVVGQPPASQVTSIGQQVAESS--SGDPNTSAGFSTPVPADSTSLLVSEGTATPG 352
              P+      PPA+   S     A +    G P T A  + P P    +    +G  TP 
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA-TLPSPKGGPATPSLKGAPTPP 1083

Query: 353  SS--PSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAG 410
            ++  PSP G    P+P    +PP   +P  P  G    P  G    + + P     S  G
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPA-ATPPSPKGGLATPPHKG----APTTPAATPPSPKG 1138

Query: 411  DASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTD-QRPTPEPF 469
              ++  P  +    A    A P S     +      A  +PA  P + K     P+P+  
Sbjct: 1139 GLATPPPKGAPTTPA----ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA 1194

Query: 470  PATSKERPRS 479
            P T    P S
Sbjct: 1195 PTTPAATPPS 1204



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 64/266 (24%), Positives = 87/266 (32%), Gaps = 27/266 (10%)

Query: 245  PPPPYYPPEYTCTP-------STEAQRGLHLDFAPSPFGTLYDVAINSP--GLLYPAELP 295
            PPP   P     TP       +T + +G     A +P      +A  SP      PA  P
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225

Query: 296  PPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPG--- 352
            P  +  +  P      +       S  G P T      P P  +T   +  G ATP    
Sbjct: 1226 PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKG 1285

Query: 353  -------SSPSPDG------PVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTS 399
                   + PSP G      P GAP P     P    SP  P       P          
Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345

Query: 400  DPTLCTSSMAGDASSHRPSCSQ-DLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTW 458
             PTL  ++ +       PS  +       + +  G  +M+  +     A  SP GDP T 
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP-TS 1404

Query: 459  KTDQRPTPEPFPATSKERPRSLVDSK 484
                  +P+  PAT   R  +   SK
Sbjct: 1405 PAVIPLSPKKAPATPVTREGAATPSK 1430



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 61/268 (22%), Positives = 91/268 (33%), Gaps = 40/268 (14%)

Query: 246  PPPYYPPEYTCTPSTEAQRGLHLDFA---PSPFGTL----YDVAINSPGLLYPAE----L 294
            PP   PP     P+T + +G  +  A   PSP G L    +  A  +P    P+      
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141

Query: 295  PPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSA--------GFSTPVPADSTSLLVSE 346
             PP +     P A+  +  G        G P T A        G +TP P  + +   + 
Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201

Query: 347  ------GTATPG----------SSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPG 390
                  G ATP           + PSP G +  P+P      P   +P  P  G    P 
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGPATPPP 1260

Query: 391  PGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLS 450
             G  +   + P      +A       P+ +  +     +  P ++    + T       S
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAV-VTPPSPKGGPATSPPKGAPTPPAATPPS 1319

Query: 451  PAGDPDTWKTDQRPTPEPFPATSKERPR 478
            P G P T      PTP   PA +   P+
Sbjct: 1320 PKGSPGTPPPKGAPTP---PAVTPPSPK 1344



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 54/217 (24%), Positives = 74/217 (34%), Gaps = 16/217 (7%)

Query: 259  STEAQRGLHLDFAPSPFGTLYDVAIN--SPG--LLYPAELPPPYEAVVGQPPASQVTSIG 314
            S ++    H    PSP G     A+   SP    L P E P P    +  P     T   
Sbjct: 846  SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905

Query: 315  QQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSS--PSPDGPVGAPAPSEPALP 372
            +Q    S    +     +TP P    +    +G  TP ++  PSP G    P+P     P
Sbjct: 906  KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965

Query: 373  PGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVP 432
            P    P     G    P P     + + P     S  G  ++  P  +    A      P
Sbjct: 966  PAATPPSP--KGGPATPSP---KGAPTPPAATPPSPKGGPATPSPKGAPTPPA----VTP 1016

Query: 433  GSASMSRSATAACR-AQLSPAGDPDTWKTDQRPTPEP 468
             S   S +AT   + A   PA  P + K     TP P
Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 79/311 (25%), Positives = 107/311 (34%), Gaps = 56/311 (18%)

Query: 213  PQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFA- 271
            P +  P NP  VTP            +  P   PP   PP    +P T   +G     A 
Sbjct: 1282 PHKGAP-NPAVVTPPSPKGGPATSPPKGAPT--PPAATPPSPKGSPGTPPPKGAPTPPAV 1338

Query: 272  --PSPFGTLYDVAIN-----SPGLLYPAELPPPYEAVV---GQPPASQVTSIGQQVAESS 321
              PSP GT    A        P      E P P  A     G P  +  +        S 
Sbjct: 1339 TPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398

Query: 322  SGDPNTSAGFSTPVPADSTSLLVSEGTATPGS---------------SPSPDGPVGAPA- 365
             GDP + A           + +  EG ATP                 +P+   P G PA 
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458

Query: 366  ------PSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSD---PTLCTSSMAGDASSHR 416
                  P+ PA+ P   SP++P       P P +V+ S+S    P       A    +  
Sbjct: 1459 PSSKGDPTLPAVTPP--SPKEP-------PAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509

Query: 417  PSCSQDLEAGLSEA----VPGSASMSRS--ATAACRAQLSPAGD--PDTWKTDQRPTPEP 468
            PS  +++ A  S       P +  +S+   AT A +  L P     P   KT   PTP+ 
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569

Query: 469  FPATSKERPRS 479
             PAT   +  S
Sbjct: 1570 APATPSSKEAS 1580



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 50/226 (22%), Positives = 82/226 (36%), Gaps = 30/226 (13%)

Query: 203 VSSDVLQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEFI-PPLPPP------PYYPPEYT 255
           ++S  L++  PQ S         P GT           I PP+ P       P   P   
Sbjct: 73  IASTPLEVPFPQSSSGT----ALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLK 128

Query: 256 CTPSTEAQRGL----------HLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQP 305
            TPS+ A   L             F P+   +   VA+   G +     P     +    
Sbjct: 129 GTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAP-----IAPSE 183

Query: 306 PASQVTSIGQQVAESSSGDPNTSAGFST-PVPADSTSLLVSEGTAT-PGSSPSPDGPVGA 363
           P + +  +  +V  +  G P+     ST P    +    +  G A+ P ++P+    + +
Sbjct: 184 PKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIAS 243

Query: 364 PAPSEPALPPGHVSPEDPGMGSQVQP--GPGRVSRSTSDPTLCTSS 407
           P   +  +    +SP++PG  S   P   P  +S ST    + TSS
Sbjct: 244 PQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSS 289



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 65/281 (23%), Positives = 99/281 (35%), Gaps = 42/281 (14%)

Query: 221  PTCVTPHGTVLHQTLDFDEFIPPLPPP-PYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLY 279
            P    P G     +   D  +P + PP P  PP      ++ + +      AP    TL 
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506

Query: 280  DVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSA--------GF 331
             V  +SP      E+P          P+S+   I       S   P T A          
Sbjct: 1507 AVIPSSP-----KEVPAT--------PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553

Query: 332  STPVPADSTSLLV-SEGTATPGSSPSPDGPV-------GAPAPSEPALPPGHVSP---ED 380
            + P P  + ++    E  ATP S  +   P        GAP+P E  +PP   SP   E 
Sbjct: 1554 TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA 1613

Query: 381  PGMGSQVQPGPGR-----VSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSA 435
            P   +   P P +       + T      T S   D+ +   S +  + A + +A  G  
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLP 1673

Query: 436  SMSRSATAACRAQLSPAGDPD---TWKTDQRPTPEPFPATS 473
            +  +  TA     ++PA +     T  T + P  +   ATS
Sbjct: 1674 A-KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATS 1713


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 45/179 (25%), Positives = 71/179 (39%), Gaps = 22/179 (12%)

Query: 296 PPYEAVVGQPPASQVTSI-------GQQVAESSSGDPNTSAGFSTPVPADSTSLLVS--- 345
           P   +  G P  + +T +       G     S +G P+T++    P  A  T +L     
Sbjct: 362 PSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSI 421

Query: 346 ---EGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPT 402
              + TA+P  +P    P G P  + P   P   SP     G+Q    P   S ST+ PT
Sbjct: 422 TKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASP----TGTQSTASP-TGSPSTASPT 476

Query: 403 LCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAA----CRAQLSPAGDPDT 457
              S+ +   S  R S ++         +  +AS++R+ + A      +  SP G P T
Sbjct: 477 GSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPST 535



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 59/280 (21%), Positives = 98/280 (35%), Gaps = 54/280 (19%)

Query: 218 PANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGT 277
           P+ P+  +P GT    +L                     TPST +   + +    SP G 
Sbjct: 278 PSRPSTASPTGTPSRASLSM-------------------TPSTASL--MRMLPRASPTGM 316

Query: 278 LYDVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPA 337
           L   ++            PP  ++   P  S+ +  G+    S +G P+ ++   +P  A
Sbjct: 317 LSRTSLTKMDSTASISRTPPRASITRTP--SRASPTGKPSTASPTGTPSRASPTGSPSTA 374

Query: 338 DSTSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSP------------------- 378
             T L     TA+P  +P    P G P+ +     P   SP                   
Sbjct: 375 SLTGL---SSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPT 431

Query: 379 EDPGMGSQVQPGP-----GRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPG 433
             P   S     P     G  SR++   T  T+S  G  S+  P+ S    +      P 
Sbjct: 432 RTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGS--PS 489

Query: 434 SASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPATS 473
            AS++R+ + A   ++         +T  R +P   P+T+
Sbjct: 490 RASLTRTPSRASLTKMESTA--SITRTPSRASPTWTPSTA 527



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 67/283 (23%), Positives = 96/283 (33%), Gaps = 57/283 (20%)

Query: 243 PLPPPPYYPPEYTCTPSTEAQRGLHLDFAP---SPFGTLYDVAINSPGLLYPAELPPPYE 299
           P   PP   P  T TPST +     L   P   SP G L   +I            PP  
Sbjct: 385 PTGTPPRASP--TGTPSTAS-----LTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRA 437

Query: 300 AVVGQPPA-------SQVTSIGQQVAESSSGDPNTSAGFSTPVPADST------------ 340
           +  G PP        S+ +  G Q   S +G P+T++   +P  A  T            
Sbjct: 438 SPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTP 497

Query: 341 ---SLLVSEGTAT------------------PGSSPSPDGPVGAPAPSEPALPPGHVS-P 378
              SL   E TA+                  P  SPS    +G+P+ +     P   S  
Sbjct: 498 SRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLT 557

Query: 379 EDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDAS----SHRPSCSQDLEAGLSEAVPGS 434
             P   S   P    ++R+ S  T+  + M   AS      R S +    + L   +  +
Sbjct: 558 RTPSRASLTTPSRASLTRTPS--TVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDST 615

Query: 435 ASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPATSKERP 477
           AS++R+   A   +  P   P        PT  P  A+    P
Sbjct: 616 ASITRTPPRASPTETPPRASPTGTPPRASPTGTPPRASPTGTP 658



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 47/189 (24%), Positives = 63/189 (33%), Gaps = 17/189 (8%)

Query: 303 GQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLL----------VSEGTATPG 352
           G PP +  T  G     S S  P+T+    TP  A  T +L           +  T TP 
Sbjct: 222 GTPPRASPT--GSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTP- 278

Query: 353 SSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDA 412
           S PS   P G P+ +  ++ P   S       +       R S +  D T   S     A
Sbjct: 279 SRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRA 338

Query: 413 S----SHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEP 468
           S      R S +           P  AS + S + A    LS    P        PT  P
Sbjct: 339 SITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTP 398

Query: 469 FPATSKERP 477
             A+   +P
Sbjct: 399 STASLTRKP 407


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 63/277 (22%), Positives = 99/277 (35%), Gaps = 29/277 (10%)

Query: 245 PPPPYYPPEYTCTPSTEAQRGLHLDFAPSP---FGTLYDVAINSPGLLYPAELPPPYEAV 301
           PP  +  P     P   ++ G  +  AP P     T   V + +PG   PA +P   E  
Sbjct: 11  PPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPGSAETS 70

Query: 302 VGQP-----PASQVTSIGQQV----AESSSGDPNTSAGFSTPVPAD----STSLLVSEGT 348
              P     PA  VT     V    A   +  P   +G  +P PA      TS  ++ G 
Sbjct: 71  APAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGA 130

Query: 349 -------ATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDP 401
                  A P  +P P  P G P  +     PG ++ + P     + P PG    S    
Sbjct: 131 DSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPP-----LAPKPGTTVASGVTA 185

Query: 402 TLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTD 461
              +  + G   +   + +   +A    + PG+              ++PA +P     D
Sbjct: 186 RSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAVVTVTPAPEPAENSQD 245

Query: 462 QRPTPEPFPATSKERPRSLVDSKAYADARVLVAKFLE 498
              T    P  S  R ++  D+ +Y D+  L++  LE
Sbjct: 246 LGSTSSLGPGISGPRGQA-PDTLSYLDSVSLMSGTLE 281


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 54/191 (28%), Positives = 76/191 (39%), Gaps = 23/191 (12%)

Query: 292  AELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATP 351
            AE P P EA    PP   ++S+  + ++ S+   +  +    P    S  LL   G + P
Sbjct: 1319 AEHPAP-EAPESSPPLP-LSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376

Query: 352  -GSSPSPDGPVGAPA---PSEPALPPGHVSPEDPGMGSQVQPG-PGRVSRSTSDPTLCTS 406
             G+ P+P  P   P    P + A P     PE P  G+  Q G PG     TS+  L TS
Sbjct: 1377 PGAPPAPLAPSSPPVTALPQDGAAPATSTMPE-PASGTASQAGGPGTPQGLTSE--LETS 1433

Query: 407  SMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTP 466
                + +   P   Q L  GL+   P   + S    +A R  L P            P P
Sbjct: 1434 QPLAE-THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPP------------PAP 1480

Query: 467  EPFPATSKERP 477
            EP P +   +P
Sbjct: 1481 EPSPHSGTPQP 1491



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 45/151 (29%), Positives = 54/151 (35%), Gaps = 13/151 (8%)

Query: 241 IPPLPPPPYYPPEY----TCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPP 296
           +PP+PPP Y+ P         P   A   L L     P      +A+    ++  A    
Sbjct: 825 VPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATI 884

Query: 297 PYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPAD---STSLLVSEGTATPGS 353
           P  AV   PP     SI   VA+   G P   A F    P D   S    V    ATP  
Sbjct: 885 PLLAVA--PPGVAALSIHSAVAQ-LPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQ 941

Query: 354 SPSPDGPVGAP---APSEPALPPGHVSPEDP 381
              P  P   P    P +P LPP  V P  P
Sbjct: 942 PALPPQPTLPPQPVLPPQPTLPPQPVLPPQP 972



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 73/304 (24%), Positives = 100/304 (32%), Gaps = 60/304 (19%)

Query: 190  VCALATAMCCMQMVSSDVLQMFLPQRSHPANPTCVTPHGTVLHQ-------------TLD 236
            V AL+      Q+    V     PQ +    P   +PH TV +              TL 
Sbjct: 894  VAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPP--SPHHTVQNMRATPPQPALPPQPTLP 951

Query: 237  FDEFIPP---LPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGL-LYPA 292
                +PP   LPP P  PP+ T  P             P P      V    P L + P 
Sbjct: 952  PQPVLPPQPTLPPQPVLPPQPTRPPQPV--------LPPQPMLPPQPVLPPQPALPVRPE 1003

Query: 293  ELPP--PYEAVVGQPPASQVTSIGQQ-------VAESSSGDPNTSAGFSTPVPADSTSLL 343
             L P  P +A     P SQ+  +G          A+  +     +A  S P+P     +L
Sbjct: 1004 PLQPHLPEQAAPAATPGSQIL-LGHPAPYAVDVAAQVPTVPVPPAAVLSPPLP----EVL 1058

Query: 344  VSEGTATPGSSPSPDGPVGAPAPSEPA-----LPPGHVS-PEDPGMGS-----QVQPGPG 392
            +          PS    V A   S P      LPP +   P  PG+ S     Q+   P 
Sbjct: 1059 LPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPV 1118

Query: 393  RVSRSTSD-----PTLCTSSMAGDASSHR---PSCSQDLEAGLSEAVPGSASMSRSATAA 444
            +  +++ D     P  C S    D +S +    SC      G  E         RS  A 
Sbjct: 1119 QEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRAR 1178

Query: 445  CRAQ 448
             R +
Sbjct: 1179 SRQE 1182


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 52/193 (26%), Positives = 73/193 (37%), Gaps = 30/193 (15%)

Query: 241  IPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYE- 299
            +PP  P    PP  T +P    + GL L   P P  +   V +     L+   LPPP E 
Sbjct: 1518 VPPPSPRRSVPPSPT-SPRASEENGLPLLVLPPPAPS---VDVEDGEFLFVEPLPPPLEF 1573

Query: 300  ----------AVVGQP--------PASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTS 341
                         G P        PA+ +  +       ++  P   +  S+    DS  
Sbjct: 1574 SNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAV--AAAPPTLDSTASSLTSYDSEV 1631

Query: 342  LLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDP 401
              +++G +     P P GP    AP+  A  PG   P  PG  S ++      SRS+SD 
Sbjct: 1632 ATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPP--PGTDSGIEEVD---SRSSSDH 1686

Query: 402  TLCTSSMAGDASS 414
             L T S A   SS
Sbjct: 1687 PLETISSASTLSS 1699



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 67/276 (24%), Positives = 91/276 (32%), Gaps = 45/276 (16%)

Query: 243  PLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPG---LLYPAELPPPYE 299
            P PPP    P Y   P T      H      P   L+  +   P    L Y A L    +
Sbjct: 1374 PQPPPRPPSPRYEAPPPTPHHHSPHAHH--EPVLRLWGASPPDPARRELGYRAGLGSQEK 1431

Query: 300  AVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDG 359
            ++   PPA++ + + +         P T+ G           LL+  GT  P   P    
Sbjct: 1432 SLPASPPAARRSLLHRL--------PPTAPGVGP--------LLLQLGTEPPAPHPGVSK 1475

Query: 360  PVGAPAPSEPALPPGHV---------SPEDPGMGSQVQPGPG--RVSRSTSDPTLCTSSM 408
            P  + AP EP   P HV         +P   G G   + GPG    S   S P   TS  
Sbjct: 1476 PWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPR 1535

Query: 409  AGDASS------HRPSCSQDLEAG-------LSEAVPGSASMSRSATAACRAQLSPAGDP 455
            A + +         P+ S D+E G       L   +  S S  +  +        P  D 
Sbjct: 1536 ASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDT 1595

Query: 456  DTWKTDQRPTPEPFPATSKERPRSLVDSKAYADARV 491
                T   P P P  A +     S   S    D+ V
Sbjct: 1596 PAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEV 1631



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 50/203 (24%), Positives = 68/203 (33%), Gaps = 7/203 (3%)

Query: 291  PAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTAT 350
            P  LP     +    P + VTS     +E   G P  S   S  VP   TS   SE    
Sbjct: 1485 PERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRS--VPPSPTSPRASEENGL 1542

Query: 351  P-----GSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCT 405
            P       +PS D   G     EP  PP   S       S + PGP      T  P    
Sbjct: 1543 PLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPL 1602

Query: 406  SSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPT 465
              +   A +  P       + L+      A++++ A+AA      P            P 
Sbjct: 1603 PPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQ 1662

Query: 466  PEPFPATSKERPRSLVDSKAYAD 488
            P P P    +     VDS++ +D
Sbjct: 1663 PGPDPPPGTDSGIEEVDSRSSSD 1685



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 38/121 (31%), Positives = 50/121 (41%), Gaps = 16/121 (13%)

Query: 261  EAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIGQQVAES 320
            E Q+G  L  APSP          SP     +  PPP  A   +  +  + +I  + A S
Sbjct: 1119 EPQKGGGLPPAPSP---------TSPA----SPQPPPAVAAPSEKNSIPIPTIIIK-APS 1164

Query: 321  SSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPED 380
            +S    +S G ST      T    + G    GSSPSP  P  +P P  P+  P   SP  
Sbjct: 1165 TSSSGRSSQGSSTEA-EPPTQPEPTGGGGGGGSSPSP-APAMSPVPPSPSPVPTPASPSG 1222

Query: 381  P 381
            P
Sbjct: 1223 P 1223



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 33/130 (25%), Positives = 48/130 (36%), Gaps = 30/130 (23%)

Query: 284  NSPGLLYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLL 343
            ++PG  YP +L  P +              G+ +  S    P  S G   PV   S ++ 
Sbjct: 1741 STPGPPYPPQLMTPSKLR------------GRALGASGGLRPGPSGGLRDPVTPTSPTVS 1788

Query: 344  VSEGTATPG-------SSPSPDGPVGAPAPSEPALP----------PGHVSPEDPGMGSQ 386
            V+ G  T G       S P   G  G P   EP +P          P  + P + G G  
Sbjct: 1789 VT-GAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPP 1847

Query: 387  VQPGPGRVSR 396
              P PG +++
Sbjct: 1848 PPPLPGPLAQ 1857



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 35/156 (22%), Positives = 51/156 (32%), Gaps = 36/156 (23%)

Query: 291  PAELPPPYEAVVGQPPASQVTSIGQQVAE------------------------SSSGDPN 326
            P   PPP    + QP AS + ++   +                           S G  +
Sbjct: 1844 PGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGD 1903

Query: 327  TSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGA-----PAPSEPALPPGHVSPEDP 381
            +  G ++ VP + TS L  +  +    S     PV +     P P  P LP G       
Sbjct: 1904 SHHGGASYVP-ERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTG------T 1956

Query: 382  GMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRP 417
            G+       PG  S S S  +  T  + G     RP
Sbjct: 1957 GVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRP 1992


>gi|238908524 hypothetical protein LOC389333 [Homo sapiens]
          Length = 1015

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 56/217 (25%), Positives = 73/217 (33%), Gaps = 55/217 (25%)

Query: 232 HQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINS------ 285
           H T  F +   P+ P PY PPE    PS +         A  P G L   A NS      
Sbjct: 678 HYTSVFIKDFLPVVPHPYEPPE----PSFDTVAR----DASQPNGVLRRRAENSTAKPFK 729

Query: 286 ------PGLLYPAELPPPYEAVVGQPPASQVTSIGQQ---------------VAESSSGD 324
                 PG L     P     V  + P  +   +  Q                  SS   
Sbjct: 730 RTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRS 789

Query: 325 PNTSAGFSTPVPAD-----STSLLVSEGTATPGSSPSPDGPVGAPAPSEP---------- 369
           P   AG  +P P       S S  ++    TP ++P P   V AP P EP          
Sbjct: 790 PVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPA 849

Query: 370 -----ALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDP 401
                + PP   SP+ P  G++ QPG   + +   DP
Sbjct: 850 QPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDP 886


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 66/257 (25%), Positives = 81/257 (31%), Gaps = 31/257 (12%)

Query: 239 EFIPPLPPPPYYPPEYTCTPSTE-AQRGLHLDFAPSPF------GTLYDVAINSPGLLYP 291
           E + P  P P  PP    TP    AQ+  H    P P         L       PG + P
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351

Query: 292 AELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATP 351
              PP       QP         Q  +E  S +       + P     T          P
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP------AQQP 405

Query: 352 GSSPSPDGPVGAPAP-------SEPALPPGH----VSPEDPGMGSQVQPGPGRVSRSTSD 400
           G +  P   VG P P         PA  PG     V    PG     Q GPG+ S   + 
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465

Query: 401 PTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSA---SMSRSATAACRAQLSPAGDPDT 457
           PT   S + G A   +P   Q   A      PGSA   S    +T     Q  PA  P  
Sbjct: 466 PTKPPSQLPGPA---KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA-KPSP 521

Query: 458 WKTDQRPTPEPFPATSK 474
            +      P   P ++K
Sbjct: 522 QQPGSTKPPSQQPGSAK 538



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 62/264 (23%), Positives = 84/264 (31%), Gaps = 27/264 (10%)

Query: 212  LPQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFA 271
            LP  S   +     P       +LD     PP PPPP  PP                   
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP---------------P 2420

Query: 272  PSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGF 331
            P P   L       P +L   +L          P    VT++       S+G P T    
Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT 2480

Query: 332  STPVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGP 391
            + P P       +  G       P P  P  AP P  P LP     P D      + P P
Sbjct: 2481 TAPPPVPPKPSSIPSGLVFT-HRPEPSKPPIAPKPVIPQLPTTTQKPTD------IHPKP 2533

Query: 392  GRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSP 451
              +S ++S     T ++   A    PS +  L    +++ P   S S + T       S 
Sbjct: 2534 TGLSLTSS----MTLNLVTSADYKLPSPTSPLSPHSNKSSP-RFSKSLTETYVVITLPSE 2588

Query: 452  AGDPDTWKTDQRPTPEPFPATSKE 475
             G P      Q  T  P  + SK+
Sbjct: 2589 PGTPTDSSASQAITSWPLGSPSKD 2612



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 34/124 (27%), Positives = 46/124 (37%), Gaps = 10/124 (8%)

Query: 286 PGLLYPAELPPPYEAVVGQP-----PASQVTSIGQQVAESS--SGDPNTSAGFSTPVPAD 338
           PGL  PA+ P P +  V QP     PA Q    G+  A+ +  +  P+   G + P P  
Sbjct: 425 PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKPPPQQ 483

Query: 339 STSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRST 398
                       PGS+  P    G+  P      P   SP+ PG        PG    S 
Sbjct: 484 PGP--AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541

Query: 399 SDPT 402
             P+
Sbjct: 542 QQPS 545



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 10/87 (11%)

Query: 297  PYEAVVGQPPASQVTS--------IGQQVAESS--SGDPNTSAGFSTPVPADSTSLLVSE 346
            P  +V+  P   Q+++         GQ+   S   SG P+ S+  + P P   +S L   
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402

Query: 347  GTATPGSSPSPDGPVGAPAPSEPALPP 373
                P   P P  P   P P  P LPP
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPP 2429


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,098,555
Number of Sequences: 37866
Number of extensions: 1581265
Number of successful extensions: 18177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 182
Number of HSP's successfully gapped in prelim test: 1228
Number of HSP's that attempted gapping in prelim test: 10810
Number of HSP's gapped (non-prelim): 6269
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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