Guide to the Human Genome
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Search of human proteins with 16554585

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16554585 coronin, actin binding protein, 2A [Homo sapiens]
         (525 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209529711 coronin, actin binding protein, 2A [Homo sapiens]       1077   0.0  
gi|16554585 coronin, actin binding protein, 2A [Homo sapiens]        1077   0.0  
gi|148529011 coronin, actin binding protein, 2B [Homo sapiens]        670   0.0  
gi|65787364 coronin, actin binding protein, 1B [Homo sapiens]         422   e-118
gi|14149734 coronin, actin binding protein, 1B [Homo sapiens]         422   e-118
gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo sa...   410   e-114
gi|109627650 coronin 6 [Homo sapiens]                                 399   e-111
gi|5902134 coronin, actin binding protein, 1A [Homo sapiens]          396   e-110
gi|168229161 coronin 7 [Homo sapiens]                                 210   2e-54
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]          73   6e-13
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]          73   6e-13
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]          73   6e-13
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]            73   6e-13
gi|19913367 transducin beta-like 1Y [Homo sapiens]                     72   1e-12
gi|19913365 transducin beta-like 1Y [Homo sapiens]                     72   1e-12
gi|15150805 transducin beta-like 1Y [Homo sapiens]                     72   1e-12
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s...    72   1e-12
gi|23199987 WD repeat domain 5B [Homo sapiens]                         65   1e-10
gi|16554629 WD repeat domain 5 [Homo sapiens]                          65   2e-10
gi|16554627 WD repeat domain 5 [Homo sapiens]                          65   2e-10
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]             64   3e-10
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa...    63   6e-10
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa...    63   6e-10
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi...    63   6e-10
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]     60   5e-09
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               59   8e-09
gi|4757988 WD repeat domain 39 [Homo sapiens]                          57   3e-08
gi|113865883 WD repeat domain 38 [Homo sapiens]                        57   5e-08
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]              56   9e-08
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi...    55   1e-07

>gi|209529711 coronin, actin binding protein, 2A [Homo sapiens]
          Length = 525

 Score = 1077 bits (2786), Expect = 0.0
 Identities = 525/525 (100%), Positives = 525/525 (100%)

Query: 1   MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF 60
           MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF
Sbjct: 1   MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF 60

Query: 61  LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN 120
           LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN
Sbjct: 61  LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN 120

Query: 121 LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ 180
           LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ
Sbjct: 121 LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ 180

Query: 181 DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMST 240
           DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMST
Sbjct: 181 DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMST 240

Query: 241 GTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEV 300
           GTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEV
Sbjct: 241 GTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEV 300

Query: 301 SADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRR 360
           SADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRR
Sbjct: 301 SADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRR 360

Query: 361 SESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMA 420
           SESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMA
Sbjct: 361 SESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMA 420

Query: 421 PASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTE 480
           PASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTE
Sbjct: 421 PASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTE 480

Query: 481 NELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL 525
           NELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL
Sbjct: 481 NELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL 525


>gi|16554585 coronin, actin binding protein, 2A [Homo sapiens]
          Length = 525

 Score = 1077 bits (2786), Expect = 0.0
 Identities = 525/525 (100%), Positives = 525/525 (100%)

Query: 1   MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF 60
           MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF
Sbjct: 1   MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF 60

Query: 61  LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN 120
           LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN
Sbjct: 61  LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN 120

Query: 121 LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ 180
           LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ
Sbjct: 121 LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ 180

Query: 181 DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMST 240
           DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMST
Sbjct: 181 DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMST 240

Query: 241 GTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEV 300
           GTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEV
Sbjct: 241 GTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEV 300

Query: 301 SADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRR 360
           SADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRR
Sbjct: 301 SADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRR 360

Query: 361 SESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMA 420
           SESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMA
Sbjct: 361 SESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMA 420

Query: 421 PASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTE 480
           PASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTE
Sbjct: 421 PASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTE 480

Query: 481 NELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL 525
           NELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL
Sbjct: 481 NELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL 525


>gi|148529011 coronin, actin binding protein, 2B [Homo sapiens]
          Length = 480

 Score =  670 bits (1729), Expect = 0.0
 Identities = 319/519 (61%), Positives = 403/519 (77%), Gaps = 50/519 (9%)

Query: 1   MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF 60
           MSW PQYRSSKFR+V+GK A++E+C+D +PIT++VHDNHFCAVN  F+A+VTE AGGG+F
Sbjct: 6   MSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSF 65

Query: 61  LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN 120
           LVIPL QTG+++P+YPKVCGH+GNVLD+KWNPF D  IASCSED +++IW IP+  L RN
Sbjct: 66  LVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRN 125

Query: 121 LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ 180
           +T    EL GH+RRVGLVEWHPT  NILFSAGYDYKV+IWNLD  E     P+  I CH 
Sbjct: 126 MTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGE-----PVKMIDCHT 180

Query: 181 DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMST 240
           DVIL MSFNT+GSLL TTCKD+K+RVI+PR+G VLQEA+ K HR ++V+FLGN+K+L++T
Sbjct: 181 DVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTT 240

Query: 241 GTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEV 300
           G SRWN RQ+ALWDQ++LS+PL+EE++DG SG+LFPFYDADT MLY+ GKGDGNIRYYE+
Sbjct: 241 GVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEI 300

Query: 301 SADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRR 360
           S +KP+LSYL E+RS  PQKG+GVMPK GLDVS+CE+FRFYKL+T K LIEPISMIVPRR
Sbjct: 301 STEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRR 360

Query: 361 SESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMA 420
           S+SYQEDIYP T G +P+LT  EWL G+NRDP+L+SL+                      
Sbjct: 361 SDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLK---------------------- 398

Query: 421 PASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTE 480
                           +G++ SS +  K P       ++EKK+ + NG D+ E  PP+TE
Sbjct: 399 ----------------EGYKKSSKMVFKAP-------IKEKKSVVVNGIDLLENVPPRTE 435

Query: 481 NELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLR 519
           NELL+MF+RQQ+EIRRL+E L Q++++ +QL+LE+KNLR
Sbjct: 436 NELLRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLR 474


>gi|65787364 coronin, actin binding protein, 1B [Homo sapiens]
          Length = 489

 Score =  422 bits (1086), Expect = e-118
 Identities = 215/454 (47%), Positives = 297/454 (65%), Gaps = 20/454 (4%)

Query: 1   MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF 60
           MS+    R SKFRHVFG+P   + CY+ + ++R   D+ FCAVNP F+AV+ E +GGGAF
Sbjct: 1   MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 60

Query: 61  LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN 120
           LV+PL +TG++D  YP VCGH G VLD+ W P +D  IAS SED T+ +W IP+  LT  
Sbjct: 61  LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 120

Query: 121 LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ 180
           LT     L GH +RVG++ WHPTA N+L SAG D  V+IWN+ T E +        S H 
Sbjct: 121 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLD----SLHP 176

Query: 181 DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVL--QEASYKGHRASKVLFLGNLKKLM 238
           D+I ++S+N NGSL  + CKD+ +R+IDPR GT++  +E +++G R  + +FL +  K+ 
Sbjct: 177 DLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLAD-GKVF 235

Query: 239 STGTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYY 298
           +TG SR + RQ+ALWD +NL  P+  ++LD S+G L PFYD DTS++YV GKGD +IRY+
Sbjct: 236 TTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYF 295

Query: 299 EVSADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVP 358
           E++ + P++ +L  + S  PQ+G+G MPKRGL+VS CEI RFYKL   K   EPI M VP
Sbjct: 296 EITEEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERK--CEPIVMTVP 353

Query: 359 RRSESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPG--------SELLRPHPLP 410
           R+S+ +Q+D+YP TAG + +L A+EW+SG + DPIL+SLR           ++ R + L 
Sbjct: 354 RKSDLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLS 413

Query: 411 AERPIFNSMAPASPRLLNQTEKLAAEDGWRSSSL 444
             RP   +MAP S  L        A D   S SL
Sbjct: 414 DSRP---AMAPGSSHLGAPASTTTAADATPSGSL 444


>gi|14149734 coronin, actin binding protein, 1B [Homo sapiens]
          Length = 489

 Score =  422 bits (1086), Expect = e-118
 Identities = 215/454 (47%), Positives = 297/454 (65%), Gaps = 20/454 (4%)

Query: 1   MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAF 60
           MS+    R SKFRHVFG+P   + CY+ + ++R   D+ FCAVNP F+AV+ E +GGGAF
Sbjct: 1   MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 60

Query: 61  LVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRN 120
           LV+PL +TG++D  YP VCGH G VLD+ W P +D  IAS SED T+ +W IP+  LT  
Sbjct: 61  LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 120

Query: 121 LTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQ 180
           LT     L GH +RVG++ WHPTA N+L SAG D  V+IWN+ T E +        S H 
Sbjct: 121 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLD----SLHP 176

Query: 181 DVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVL--QEASYKGHRASKVLFLGNLKKLM 238
           D+I ++S+N NGSL  + CKD+ +R+IDPR GT++  +E +++G R  + +FL +  K+ 
Sbjct: 177 DLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLAD-GKVF 235

Query: 239 STGTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYY 298
           +TG SR + RQ+ALWD +NL  P+  ++LD S+G L PFYD DTS++YV GKGD +IRY+
Sbjct: 236 TTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYF 295

Query: 299 EVSADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVP 358
           E++ + P++ +L  + S  PQ+G+G MPKRGL+VS CEI RFYKL   K   EPI M VP
Sbjct: 296 EITEEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERK--CEPIVMTVP 353

Query: 359 RRSESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPG--------SELLRPHPLP 410
           R+S+ +Q+D+YP TAG + +L A+EW+SG + DPIL+SLR           ++ R + L 
Sbjct: 354 RKSDLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLS 413

Query: 411 AERPIFNSMAPASPRLLNQTEKLAAEDGWRSSSL 444
             RP   +MAP S  L        A D   S SL
Sbjct: 414 DSRP---AMAPGSSHLGAPASTTTAADATPSGSL 444


>gi|7656991 coronin, actin binding protein, 1C isoform 1 [Homo
           sapiens]
          Length = 474

 Score =  410 bits (1054), Expect = e-114
 Identities = 195/395 (49%), Positives = 276/395 (69%), Gaps = 9/395 (2%)

Query: 8   RSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQ 67
           R SKFRHVFG+    + CYD + ++R   D+ FCAVNP F+A++ E +GGGAFLV+PLH+
Sbjct: 6   RQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHK 65

Query: 68  TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
           TG++D  YP VCGH G VLD+ W P +D  IAS SED T+ +W IP+  LT +LT     
Sbjct: 66  TGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVI 125

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
           L GH++RVG+V WHPTA N+L SAG D  ++IWN+ T E++I    +    H D+I ++S
Sbjct: 126 LEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALI----NLDDMHSDMIYNVS 181

Query: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVL--QEASYKGHRASKVLFLGNLKKLMSTGTSRW 245
           +N NGSL+ T  KD+K+RVIDPR   ++  +E +++G R  + +FL +   + +TG SR 
Sbjct: 182 WNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLAD-GNVFTTGFSRM 240

Query: 246 NNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKP 305
           + RQ+ALW+  N+  P+   ++D S+GVL PFYD DTS++Y+ GKGD +IRY+E++ + P
Sbjct: 241 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP 300

Query: 306 HLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQ 365
           ++ YL  + S  PQ+G+G MPKRGLDV+ CEI RF+KL   K   EPI M VPR+S+ +Q
Sbjct: 301 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERK--CEPIIMTVPRKSDLFQ 358

Query: 366 EDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPG 400
           +D+YP TAG + +L A+EW  G N DPIL+SL+ G
Sbjct: 359 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHG 393


>gi|109627650 coronin 6 [Homo sapiens]
          Length = 472

 Score =  399 bits (1026), Expect = e-111
 Identities = 201/443 (45%), Positives = 286/443 (64%), Gaps = 10/443 (2%)

Query: 8   RSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQ 67
           R SKFRHVFG+ A  +  Y+ + +++   D+ FCAVNP F+A++ E  GGGAF+V+PL +
Sbjct: 7   RQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVLPLAK 66

Query: 68  TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
           TG++D +YP V GH   VLD+ W P +D  IAS S+D TI +W IP     RN+T     
Sbjct: 67  TGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIIT 126

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
           L GH++RVG++ WHPTA N+L SAG D  ++IWN+ T E +    +S    H DVI S+ 
Sbjct: 127 LEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVL----LSLDDMHPDVIHSVC 182

Query: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVLQE--ASYKGHRASKVLFLGNLKKLMSTGTSRW 245
           +N+NGSLLATTCKD+ +R+IDPR G V+ E  A+++G R  + +F      + +TG +R 
Sbjct: 183 WNSNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFT-RQGHIFTTGFTRM 241

Query: 246 NNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKP 305
           + R++ LWD +N   P+  +++D S+GVL PFYD D+S++Y+ GKGD +IRY+E++ + P
Sbjct: 242 SQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPP 301

Query: 306 HLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQ 365
            + YL  + S  PQ+G+G MPKRGLDVS CEI RFYKL   K   EPI M VPR+S+ +Q
Sbjct: 302 FVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERK--CEPIIMTVPRKSDLFQ 359

Query: 366 EDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPL-PAERPIFNSMAPASP 424
           +D+YP T G +P+L A EWLSG + +P+L+SLR G    +   L   +R I +   P+ P
Sbjct: 360 DDLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGP 419

Query: 425 RLLNQTEKLAAEDGWRSSSLLEE 447
           R                 +LLEE
Sbjct: 420 RRSQSASDAPLSQQHTLETLLEE 442


>gi|5902134 coronin, actin binding protein, 1A [Homo sapiens]
          Length = 461

 Score =  396 bits (1017), Expect = e-110
 Identities = 194/419 (46%), Positives = 282/419 (67%), Gaps = 8/419 (1%)

Query: 8   RSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQ 67
           RSSKFRHVFG+PA  + CY+ V ++++  D+ FCAVNP F+A++ E +GGGAFLV+PL +
Sbjct: 7   RSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLGK 66

Query: 68  TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
           TG++D + P VCGH   VLD+ W P +D  IAS SED T+ +W IP   L   L      
Sbjct: 67  TGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVT 126

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
           L GH +RVG+V WH TA N+L SAG D  +M+W++ T  +++T        H D I S+ 
Sbjct: 127 LEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEV---HPDTIYSVD 183

Query: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVLQEAS--YKGHRASKVLFLGNLKKLMSTGTSRW 245
           ++ +G L+ T+C+D+++R+I+PR GTV+ E    ++G R  + +F+    K+++TG SR 
Sbjct: 184 WSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSE-GKILTTGFSRM 242

Query: 246 NNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKP 305
           + RQVALWD  +L  PL  ++LD SSGVL PF+D DT+++Y+ GKGD +IRY+E++++ P
Sbjct: 243 SERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAP 302

Query: 306 HLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQ 365
            L YL+ + S   Q+G+G MPKRGL+V+ CEI RFYKL   +   EPI+M VPR+S+ +Q
Sbjct: 303 FLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERR--CEPIAMTVPRKSDLFQ 360

Query: 366 EDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMAPASP 424
           ED+YPPTAG  P+LTA+EWL G +  P+L+SL+ G    +   L   R +      A+P
Sbjct: 361 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAP 419


>gi|168229161 coronin 7 [Homo sapiens]
          Length = 925

 Score =  210 bits (535), Expect = 2e-54
 Identities = 140/429 (32%), Positives = 226/429 (52%), Gaps = 20/429 (4%)

Query: 9   SSKFRHVFGKPASKENCYDSVP---ITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPL 65
           SSKFRH  G    +++   ++    +T     + FCA N   +AV    + GG   V+ L
Sbjct: 470 SSKFRHAQGTVLHRDSHITNLKGLNLTTPGESDGFCA-NKLRVAVPL-LSSGGQVAVLEL 527

Query: 66  HQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYR 125
            + G+L         +   V D+ W+PFD   +A   EDA I++W +P + L   LT   
Sbjct: 528 RKPGRLPDTALPTLQNGAAVTDLAWDPFDPHRLAVAGEDARIRLWRVPAEGLEEVLTTPE 587

Query: 126 KELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILS 185
             L GH  ++  + +HP AAN+L S+ YD  V IW+L      +      +  HQD I S
Sbjct: 588 TVLTGHTEKICSLRFHPLAANVLASSSYDLTVRIWDLQAGADRL-----KLQGHQDQIFS 642

Query: 186 MSFNTNGSLLATTCKDRKIRVIDPRAG-TVLQEA-SYKGHRASKVLFLGNLKKLMSTGTS 243
           ++++ +G  LAT CKD ++RV  PR+G   LQE    KG R ++++++ + + L+ +G  
Sbjct: 643 LAWSPDGQQLATVCKDGRVRVYRPRSGPEPLQEGPGPKGGRGARIVWVCDGRCLLVSGFD 702

Query: 244 RWNNRQVALWDQDNLS-VPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSA 302
             + RQ+ L++ + L+  PL    LD +   L P YD DT ++ + GKGD  +  YE+  
Sbjct: 703 SQSERQLLLYEAEALAGGPLAVLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYELLP 762

Query: 303 DKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPR-RS 361
           + P       + S +P KG+ ++PK   DV   E+ R  +L   +S +EP++  +PR R 
Sbjct: 763 ESPFFLECNSFTSPDPHKGLVLLPKTECDVREVELMRCLRL--RQSSLEPVAFRLPRVRK 820

Query: 362 ESYQEDIYPPTAGA-QPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMA 420
           E +Q+D++P TA   +P L+A+ WL G N  P L+SL+P  ++      P E P     A
Sbjct: 821 EFFQDDVFPDTAVIWEPVLSAEAWLQGANGQPWLLSLQP-PDMSPVSQAPREAPA--RRA 877

Query: 421 PASPRLLNQ 429
           P+S + L +
Sbjct: 878 PSSAQYLEE 886



 Score =  192 bits (487), Expect = 8e-49
 Identities = 126/426 (29%), Positives = 219/426 (51%), Gaps = 24/426 (5%)

Query: 6   QYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPL 65
           ++R SKFRH   +P  +E+    +    +    +    +   IA  ++  G     ++PL
Sbjct: 3   RFRVSKFRHTEARPPRRESWISDIRAGTAPSCRNHIKSSCSLIAFNSDRPG--VLGIVPL 60

Query: 66  HQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYR 125
              G+       +  H   V D+ ++PFDDF +A+ S D T+K+W +P     + L +  
Sbjct: 61  QGQGEDKRRVAHLGCHSDLVTDLDFSPFDDFLLATGSADRTVKLWRLPGP--GQALPSAP 118

Query: 126 KELVG-HARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVIL 184
             ++G     V ++++HPT+  IL SA     V +W+   ++     P++ ++ H D++ 
Sbjct: 119 GVVLGPEDLPVEVLQFHPTSDGILVSAA-GTTVKVWDAAKQQ-----PLTELAAHGDLVQ 172

Query: 185 SMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEAS--YKGHRASKVLFLGNLKKLMSTGT 242
           S  ++ +G+L+ T CKD+++R+ DPR      +++  ++  R S++ ++G  + L+STG 
Sbjct: 173 SAVWSRDGALVGTACKDKQLRIFDPRTKPRASQSTQAHENSRDSRLAWMGTWEHLVSTGF 232

Query: 243 SRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSA 302
           ++   R+V LWD    S  L    LD S G L P  D D+ +L + GKG+  +  YEV  
Sbjct: 233 NQMREREVKLWDTRFFSSALASLTLDTSLGCLVPLLDPDSGLLVLAGKGERQLYCYEVVP 292

Query: 303 DKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSE 362
            +P LS +T+    +  +G  ++P++ L V SCE+ R  +L  T   I PI   VPR++ 
Sbjct: 293 QQPALSPVTQCVLESVLRGAALVPRQALAVMSCEVLRVLQLSDT--AIVPIGYHVPRKAV 350

Query: 363 SYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHP------LPAERPIF 416
            + ED++P TAG  P+     W +G N+    VSL P     RPHP      +P   P+ 
Sbjct: 351 EFHEDLFPDTAGCVPATDPHSWWAGDNQQVQKVSLNPA---CRPHPSFTSCLVPPAEPLP 407

Query: 417 NSMAPA 422
           ++  PA
Sbjct: 408 DTAQPA 413


>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
          Length = 526

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 47/151 (31%), Positives = 83/151 (54%), Gaps = 23/151 (15%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   V  +KW+P     +ASCS+D T+KIWS+ +++   +L A+ KE+         ++
Sbjct: 359 GHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY-------TIK 410

Query: 140 WHPTA-------ANI-LFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTN 191
           W PT        +NI L SA +D  V +W  D +  V T    T++ HQ+ + S++F+ +
Sbjct: 411 WSPTGPATSNPNSNIMLASASFDSTVRLW--DIERGVCT---HTLTKHQEPVYSVAFSPD 465

Query: 192 GSLLATTCKDRKIRVIDPRAGTVLQEASYKG 222
           G  LA+   D+ + + + ++G ++   SY+G
Sbjct: 466 GKYLASGSFDKCVHIWNTQSGNLVH--SYRG 494



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 15/161 (9%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK-------QLLTRNLTAYRKELVGHA 132
           GH   V    WNP  D  +AS S D+T +IW++ +       QL+ R+        V   
Sbjct: 179 GHESEVFICAWNPVSDL-LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 237

Query: 133 RRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNG 192
           + V  ++W+ T   +L +  YD    IW  D   +      ST+  H+  I ++ +N  G
Sbjct: 238 KDVTSLDWN-TNGTLLATGSYDGFARIWTEDGNLA------STLGQHKGPIFALKWNRKG 290

Query: 193 SLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGN 233
           + + +   D+   + D   G   Q+  +    A  V +  N
Sbjct: 291 NYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN 331



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 10/88 (11%)

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDV----- 182
           L GH   V +  W+P + ++L S   D    IWNL+   +  ++ +    C ++      
Sbjct: 177 LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 235

Query: 183 ----ILSMSFNTNGSLLATTCKDRKIRV 206
               + S+ +NTNG+LLAT   D   R+
Sbjct: 236 SNKDVTSLDWNTNGTLLATGSYDGFARI 263


>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
          Length = 526

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 47/151 (31%), Positives = 83/151 (54%), Gaps = 23/151 (15%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   V  +KW+P     +ASCS+D T+KIWS+ +++   +L A+ KE+         ++
Sbjct: 359 GHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY-------TIK 410

Query: 140 WHPTA-------ANI-LFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTN 191
           W PT        +NI L SA +D  V +W  D +  V T    T++ HQ+ + S++F+ +
Sbjct: 411 WSPTGPATSNPNSNIMLASASFDSTVRLW--DIERGVCT---HTLTKHQEPVYSVAFSPD 465

Query: 192 GSLLATTCKDRKIRVIDPRAGTVLQEASYKG 222
           G  LA+   D+ + + + ++G ++   SY+G
Sbjct: 466 GKYLASGSFDKCVHIWNTQSGNLVH--SYRG 494



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 15/161 (9%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK-------QLLTRNLTAYRKELVGHA 132
           GH   V    WNP  D  +AS S D+T +IW++ +       QL+ R+        V   
Sbjct: 179 GHESEVFICAWNPVSDL-LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 237

Query: 133 RRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNG 192
           + V  ++W+ T   +L +  YD    IW  D   +      ST+  H+  I ++ +N  G
Sbjct: 238 KDVTSLDWN-TNGTLLATGSYDGFARIWTEDGNLA------STLGQHKGPIFALKWNRKG 290

Query: 193 SLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGN 233
           + + +   D+   + D   G   Q+  +    A  V +  N
Sbjct: 291 NYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN 331



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 10/88 (11%)

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDV----- 182
           L GH   V +  W+P + ++L S   D    IWNL+   +  ++ +    C ++      
Sbjct: 177 LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 235

Query: 183 ----ILSMSFNTNGSLLATTCKDRKIRV 206
               + S+ +NTNG+LLAT   D   R+
Sbjct: 236 SNKDVTSLDWNTNGTLLATGSYDGFARI 263


>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
          Length = 577

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 47/151 (31%), Positives = 83/151 (54%), Gaps = 23/151 (15%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   V  +KW+P     +ASCS+D T+KIWS+ +++   +L A+ KE+         ++
Sbjct: 410 GHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY-------TIK 461

Query: 140 WHPTA-------ANI-LFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTN 191
           W PT        +NI L SA +D  V +W  D +  V T    T++ HQ+ + S++F+ +
Sbjct: 462 WSPTGPATSNPNSNIMLASASFDSTVRLW--DIERGVCT---HTLTKHQEPVYSVAFSPD 516

Query: 192 GSLLATTCKDRKIRVIDPRAGTVLQEASYKG 222
           G  LA+   D+ + + + ++G ++   SY+G
Sbjct: 517 GKYLASGSFDKCVHIWNTQSGNLVH--SYRG 545



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 15/161 (9%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK-------QLLTRNLTAYRKELVGHA 132
           GH   V    WNP  D  +AS S D+T +IW++ +       QL+ R+        V   
Sbjct: 230 GHESEVFICAWNPVSDL-LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 288

Query: 133 RRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNG 192
           + V  ++W+ T   +L +  YD    IW  D   +      ST+  H+  I ++ +N  G
Sbjct: 289 KDVTSLDWN-TNGTLLATGSYDGFARIWTEDGNLA------STLGQHKGPIFALKWNRKG 341

Query: 193 SLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGN 233
           + + +   D+   + D   G   Q+  +    A  V +  N
Sbjct: 342 NYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN 382



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 10/88 (11%)

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDV----- 182
           L GH   V +  W+P + ++L S   D    IWNL+   +  ++ +    C ++      
Sbjct: 228 LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 286

Query: 183 ----ILSMSFNTNGSLLATTCKDRKIRV 206
               + S+ +NTNG+LLAT   D   R+
Sbjct: 287 SNKDVTSLDWNTNGTLLATGSYDGFARI 314


>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
          Length = 577

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 47/151 (31%), Positives = 83/151 (54%), Gaps = 23/151 (15%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   V  +KW+P     +ASCS+D T+KIWS+ +++   +L A+ KE+         ++
Sbjct: 410 GHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY-------TIK 461

Query: 140 WHPTA-------ANI-LFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTN 191
           W PT        +NI L SA +D  V +W  D +  V T    T++ HQ+ + S++F+ +
Sbjct: 462 WSPTGPATSNPNSNIMLASASFDSTVRLW--DIERGVCT---HTLTKHQEPVYSVAFSPD 516

Query: 192 GSLLATTCKDRKIRVIDPRAGTVLQEASYKG 222
           G  LA+   D+ + + + ++G ++   SY+G
Sbjct: 517 GKYLASGSFDKCVHIWNTQSGNLVH--SYRG 545



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 15/161 (9%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK-------QLLTRNLTAYRKELVGHA 132
           GH   V    WNP  D  +AS S D+T +IW++ +       QL+ R+        V   
Sbjct: 230 GHESEVFICAWNPVSDL-LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 288

Query: 133 RRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNG 192
           + V  ++W+ T   +L +  YD    IW  D   +      ST+  H+  I ++ +N  G
Sbjct: 289 KDVTSLDWN-TNGTLLATGSYDGFARIWTEDGNLA------STLGQHKGPIFALKWNRKG 341

Query: 193 SLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGN 233
           + + +   D+   + D   G   Q+  +    A  V +  N
Sbjct: 342 NYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN 382



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 10/88 (11%)

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDV----- 182
           L GH   V +  W+P + ++L S   D    IWNL+   +  ++ +    C ++      
Sbjct: 228 LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVP 286

Query: 183 ----ILSMSFNTNGSLLATTCKDRKIRV 206
               + S+ +NTNG+LLAT   D   R+
Sbjct: 287 SNKDVTSLDWNTNGTLLATGSYDGFARI 314


>gi|19913367 transducin beta-like 1Y [Homo sapiens]
          Length = 522

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 45/151 (29%), Positives = 82/151 (54%), Gaps = 23/151 (15%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   V  +KW+P     +ASCS+D T+KIWS+ +     +L A+ KE+         ++
Sbjct: 357 GHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY-------TIK 408

Query: 140 WHPT--------AANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTN 191
           W PT        ++ +L SA +D  V +W  D ++ V T    T+  HQ+ + S++F+ +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLW--DVEQGVCT---HTLMKHQEPVYSVAFSPD 463

Query: 192 GSLLATTCKDRKIRVIDPRAGTVLQEASYKG 222
           G  LA+   D+ + + + ++G+++   SY+G
Sbjct: 464 GKYLASGSFDKYVHIWNTQSGSLVH--SYQG 492



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 38/162 (23%), Positives = 68/162 (41%), Gaps = 15/162 (9%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK-------QLLTRNLTAYRKELVGHA 132
           GH   V    WNP  D  +AS S D+T +IW++ +       QL+ R+        V   
Sbjct: 177 GHESEVFICAWNPVSDL-LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 235

Query: 133 RRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNG 192
           + V  ++W+ +   +L    YD    IW  +   +      ST+  H+  I ++ +N  G
Sbjct: 236 KDVTSLDWN-SDGTLLAMGSYDGFARIWTENGNLA------STLGQHKGPIFALKWNKKG 288

Query: 193 SLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNL 234
           + + +   D+   + D   G   Q+  +    A  V +  N+
Sbjct: 289 NYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNM 330


>gi|19913365 transducin beta-like 1Y [Homo sapiens]
          Length = 522

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 45/151 (29%), Positives = 82/151 (54%), Gaps = 23/151 (15%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   V  +KW+P     +ASCS+D T+KIWS+ +     +L A+ KE+         ++
Sbjct: 357 GHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY-------TIK 408

Query: 140 WHPT--------AANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTN 191
           W PT        ++ +L SA +D  V +W  D ++ V T    T+  HQ+ + S++F+ +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLW--DVEQGVCT---HTLMKHQEPVYSVAFSPD 463

Query: 192 GSLLATTCKDRKIRVIDPRAGTVLQEASYKG 222
           G  LA+   D+ + + + ++G+++   SY+G
Sbjct: 464 GKYLASGSFDKYVHIWNTQSGSLVH--SYQG 492



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 38/162 (23%), Positives = 68/162 (41%), Gaps = 15/162 (9%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK-------QLLTRNLTAYRKELVGHA 132
           GH   V    WNP  D  +AS S D+T +IW++ +       QL+ R+        V   
Sbjct: 177 GHESEVFICAWNPVSDL-LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 235

Query: 133 RRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNG 192
           + V  ++W+ +   +L    YD    IW  +   +      ST+  H+  I ++ +N  G
Sbjct: 236 KDVTSLDWN-SDGTLLAMGSYDGFARIWTENGNLA------STLGQHKGPIFALKWNKKG 288

Query: 193 SLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNL 234
           + + +   D+   + D   G   Q+  +    A  V +  N+
Sbjct: 289 NYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNM 330


>gi|15150805 transducin beta-like 1Y [Homo sapiens]
          Length = 522

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 45/151 (29%), Positives = 82/151 (54%), Gaps = 23/151 (15%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   V  +KW+P     +ASCS+D T+KIWS+ +     +L A+ KE+         ++
Sbjct: 357 GHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY-------TIK 408

Query: 140 WHPT--------AANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTN 191
           W PT        ++ +L SA +D  V +W  D ++ V T    T+  HQ+ + S++F+ +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLW--DVEQGVCT---HTLMKHQEPVYSVAFSPD 463

Query: 192 GSLLATTCKDRKIRVIDPRAGTVLQEASYKG 222
           G  LA+   D+ + + + ++G+++   SY+G
Sbjct: 464 GKYLASGSFDKYVHIWNTQSGSLVH--SYQG 492



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 38/162 (23%), Positives = 68/162 (41%), Gaps = 15/162 (9%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK-------QLLTRNLTAYRKELVGHA 132
           GH   V    WNP  D  +AS S D+T +IW++ +       QL+ R+        V   
Sbjct: 177 GHESEVFICAWNPVSDL-LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 235

Query: 133 RRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNG 192
           + V  ++W+ +   +L    YD    IW  +   +      ST+  H+  I ++ +N  G
Sbjct: 236 KDVTSLDWN-SDGTLLAMGSYDGFARIWTENGNLA------STLGQHKGPIFALKWNKKG 288

Query: 193 SLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNL 234
           + + +   D+   + D   G   Q+  +    A  V +  N+
Sbjct: 289 NYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNM 330


>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
           sapiens]
          Length = 514

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 45/151 (29%), Positives = 81/151 (53%), Gaps = 23/151 (15%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   V  +KW+P  +  +ASCS+D T+KIWS+ +     +L A+ KE+         ++
Sbjct: 347 GHTNEVNAIKWDPTGNL-LASCSDDMTLKIWSMKQDNCVHDLQAHNKEIY-------TIK 398

Query: 140 WHPTA-------ANI-LFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTN 191
           W PT        AN+ L SA +D  V +W++D    +      T++ HQ+ + S++F+ +
Sbjct: 399 WSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICI-----HTLTKHQEPVYSVAFSPD 453

Query: 192 GSLLATTCKDRKIRVIDPRAGTVLQEASYKG 222
           G  LA+   D+ + + + + G ++   SY+G
Sbjct: 454 GRYLASGSFDKCVHIWNTQTGALVH--SYRG 482



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 15/161 (9%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK-------QLLTRNLTAYRKELVGHA 132
           GH   V    WNP  D  +AS S D+T +IW++ +       QL+ R+      + V   
Sbjct: 167 GHESEVFICAWNPVSDL-LASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSN 225

Query: 133 RRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNG 192
           + V  ++W+ +   +L +  YD    IW  D   +      ST+  H+  I ++ +N  G
Sbjct: 226 KDVTSLDWN-SEGTLLATGSYDGFARIWTKDGNLA------STLGQHKGPIFALKWNKKG 278

Query: 193 SLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGN 233
           + + +   D+   + D   G   Q+  +    A  V +  N
Sbjct: 279 NFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSN 319



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 10/88 (11%)

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISC----HQDV- 182
           L GH   V +  W+P + ++L S   D    IWNL    +  ++ +    C     QDV 
Sbjct: 165 LRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVP 223

Query: 183 ----ILSMSFNTNGSLLATTCKDRKIRV 206
               + S+ +N+ G+LLAT   D   R+
Sbjct: 224 SNKDVTSLDWNSEGTLLATGSYDGFARI 251



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 27/126 (21%), Positives = 52/126 (41%), Gaps = 15/126 (11%)

Query: 81  HRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEW 140
           H+G +  +KWN   +F I S   D T  IW         +    +++   H+     V+W
Sbjct: 265 HKGPIFALKWNKKGNF-ILSAGVDKTTIIWD-------AHTGEAKQQFPFHSAPALDVDW 316

Query: 141 HPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCK 200
              + N   S   D  + +  L         P+ T   H + + ++ ++  G+LLA+   
Sbjct: 317 Q--SNNTFASCSTDMCIHVCKLGQDR-----PIKTFQGHTNEVNAIKWDPTGNLLASCSD 369

Query: 201 DRKIRV 206
           D  +++
Sbjct: 370 DMTLKI 375


>gi|23199987 WD repeat domain 5B [Homo sapiens]
          Length = 330

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 43/149 (28%), Positives = 70/149 (46%), Gaps = 15/149 (10%)

Query: 69  GKLDPHYPKVC-GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
           G  D  Y K   GH   + DV W+  D   + S S+D T+K+W +             K 
Sbjct: 69  GAYDGKYEKTLYGHNLEISDVAWSS-DSSRLVSASDDKTLKLWDVRSGKCL-------KT 120

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
           L GH+  V    ++P + N++ S  +D  V IW + T +      + T+S H D + ++ 
Sbjct: 121 LKGHSNYVFCCNFNPPS-NLIISGSFDETVKIWEVKTGKC-----LKTLSAHSDPVSAVH 174

Query: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVLQ 216
           FN +GSL+ +   D   R+ D  +G  L+
Sbjct: 175 FNCSGSLIVSGSYDGLCRIWDAASGQCLK 203



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 13/121 (10%)

Query: 88  VKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEWHPTAANI 147
           VK++P   + I + + D T+K+W   +    +  T ++ E     +      +  T    
Sbjct: 216 VKFSPNGKY-ILTATLDNTLKLWDYSRGRCLKTYTGHKNE-----KYCIFANFSVTGGKW 269

Query: 148 LFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTC--KDRKIR 205
           + S   D  V IWNL TKE V       +  H DV++S + +   +L+A+     D+ I+
Sbjct: 270 IVSGSEDNLVYIWNLQTKEIV-----QKLQGHTDVVISAACHPTENLIASAALENDKTIK 324

Query: 206 V 206
           +
Sbjct: 325 L 325


>gi|16554629 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 43/149 (28%), Positives = 73/149 (48%), Gaps = 15/149 (10%)

Query: 69  GKLDPHYPK-VCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
           G  D  + K + GH+  + DV W+  D   + S S+D T+KIW +             K 
Sbjct: 73  GAYDGKFEKTISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDVSSGKCL-------KT 124

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
           L GH+  V    ++P + N++ S  +D  V IW++ T + + T P      H D + ++ 
Sbjct: 125 LKGHSNYVFCCNFNPQS-NLIVSGSFDESVRIWDVKTGKCLKTLP-----AHSDPVSAVH 178

Query: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVLQ 216
           FN +GSL+ ++  D   R+ D  +G  L+
Sbjct: 179 FNRDGSLIVSSSYDGLCRIWDTASGQCLK 207



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 14/153 (9%)

Query: 78  VCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGL 137
           + GH   V  VK++P  ++ +AS S D  IKIW             + K + GH   +  
Sbjct: 41  LAGHTKAVSSVKFSPNGEW-LASSSADKLIKIWGAYDG-------KFEKTISGHKLGISD 92

Query: 138 VEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLAT 197
           V W  + +N+L SA  D  + IW++ + +      + T+  H + +   +FN   +L+ +
Sbjct: 93  VAWS-SDSNLLVSASDDKTLKIWDVSSGKC-----LKTLKGHSNYVFCCNFNPQSNLIVS 146

Query: 198 TCKDRKIRVIDPRAGTVLQEASYKGHRASKVLF 230
              D  +R+ D + G  L+         S V F
Sbjct: 147 GSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 30/121 (24%), Positives = 56/121 (46%), Gaps = 13/121 (10%)

Query: 88  VKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEWHPTAANI 147
           VK++P   + +A+ + D T+K+W   K    +  T ++ E     +      +  T    
Sbjct: 220 VKFSPNGKYILAA-TLDNTLKLWDYSKGKCLKTYTGHKNE-----KYCIFANFSVTGGKW 273

Query: 148 LFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTC--KDRKIR 205
           + S   D  V IWNL TKE V       +  H DV++S + +   +++A+     D+ I+
Sbjct: 274 IVSGSEDNLVYIWNLQTKEIV-----QKLQGHTDVVISTACHPTENIIASAALENDKTIK 328

Query: 206 V 206
           +
Sbjct: 329 L 329


>gi|16554627 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 43/149 (28%), Positives = 73/149 (48%), Gaps = 15/149 (10%)

Query: 69  GKLDPHYPK-VCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
           G  D  + K + GH+  + DV W+  D   + S S+D T+KIW +             K 
Sbjct: 73  GAYDGKFEKTISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDVSSGKCL-------KT 124

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
           L GH+  V    ++P + N++ S  +D  V IW++ T + + T P      H D + ++ 
Sbjct: 125 LKGHSNYVFCCNFNPQS-NLIVSGSFDESVRIWDVKTGKCLKTLP-----AHSDPVSAVH 178

Query: 188 FNTNGSLLATTCKDRKIRVIDPRAGTVLQ 216
           FN +GSL+ ++  D   R+ D  +G  L+
Sbjct: 179 FNRDGSLIVSSSYDGLCRIWDTASGQCLK 207



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 14/153 (9%)

Query: 78  VCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGL 137
           + GH   V  VK++P  ++ +AS S D  IKIW             + K + GH   +  
Sbjct: 41  LAGHTKAVSSVKFSPNGEW-LASSSADKLIKIWGAYDG-------KFEKTISGHKLGISD 92

Query: 138 VEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLAT 197
           V W  + +N+L SA  D  + IW++ + +      + T+  H + +   +FN   +L+ +
Sbjct: 93  VAWS-SDSNLLVSASDDKTLKIWDVSSGKC-----LKTLKGHSNYVFCCNFNPQSNLIVS 146

Query: 198 TCKDRKIRVIDPRAGTVLQEASYKGHRASKVLF 230
              D  +R+ D + G  L+         S V F
Sbjct: 147 GSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 30/121 (24%), Positives = 56/121 (46%), Gaps = 13/121 (10%)

Query: 88  VKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEWHPTAANI 147
           VK++P   + +A+ + D T+K+W   K    +  T ++ E     +      +  T    
Sbjct: 220 VKFSPNGKYILAA-TLDNTLKLWDYSKGKCLKTYTGHKNE-----KYCIFANFSVTGGKW 273

Query: 148 LFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTC--KDRKIR 205
           + S   D  V IWNL TKE V       +  H DV++S + +   +++A+     D+ I+
Sbjct: 274 IVSGSEDNLVYIWNLQTKEIV-----QKLQGHTDVVISTACHPTENIIASAALENDKTIK 328

Query: 206 V 206
           +
Sbjct: 329 L 329


>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
          Length = 425

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 66/272 (24%), Positives = 108/272 (39%), Gaps = 23/272 (8%)

Query: 16  FGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHY 75
           FG    K  C   +     V+   +   NPH IA  T+       +        K DP  
Sbjct: 107 FGSVTGKIECEIKINHEGEVNRARYMPQNPHIIA--TKTPSSDVLVFDYTKHPAKPDPSG 164

Query: 76  P-----KVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVG 130
                 ++ GH+     + WN      + S S+D T+ +W I        +   +    G
Sbjct: 165 ECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTG 224

Query: 131 HARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNT 190
           H+  V  V WH    ++  S   D K+MIW  DT+ +  + P   +  H   +  +SFN 
Sbjct: 225 HSAVVEDVAWHLLHESLFGSVADDQKLMIW--DTRSNTTSKPSHLVDAHTAEVNCLSFNP 282

Query: 191 NGS-LLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFL-----GNLKKLMSTGTSR 244
               +LAT   D+ + + D R    L+  +++ H+    +F       N   L S+GT  
Sbjct: 283 YSEFILATGSADKTVALWDLR-NLKLKLHTFESHKDE--IFQVHWSPHNETILASSGT-- 337

Query: 245 WNNRQVALWDQDNLSVPLMEEDL-DGSSGVLF 275
             +R++ +WD   +      ED  DG   +LF
Sbjct: 338 --DRRLNVWDLSKIGEEQSAEDAEDGPPELLF 367



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 23/106 (21%), Positives = 44/106 (41%), Gaps = 13/106 (12%)

Query: 81  HRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK---QLLTRNLTAYRKELV----GHAR 133
           H+  +  V W+P ++  +AS   D  + +W + K   +    +      EL+    GH  
Sbjct: 315 HKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTA 374

Query: 134 RVGLVEWHPTAANILFSAGYDYKVMIWNL------DTKESVITSPM 173
           ++    W+P    ++ S   D  + IW +      D +  V TS +
Sbjct: 375 KISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSEL 420



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQL 116
           GH   + D  WNP + + I S SED  ++IW + + +
Sbjct: 371 GHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENI 407


>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
           sapiens]
          Length = 390

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 57/215 (26%), Positives = 95/215 (44%), Gaps = 17/215 (7%)

Query: 68  TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
           +G+ +P   ++ GH+     + WNP     + S S+D TI +W I        +   +  
Sbjct: 129 SGECNPDL-RLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTI 187

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
             GH   V  V WH    ++  S   D K+MIW  DT+ +  + P  ++  H   +  +S
Sbjct: 188 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIW--DTRSNNTSKPSHSVDAHTAEVNCLS 245

Query: 188 FNTNGS-LLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFL-----GNLKKLMSTG 241
           FN     +LAT   D+ + + D R    L+  S++ H+    +F       N   L S+G
Sbjct: 246 FNPYSEFILATGSADKTVALWDLR-NLKLKLHSFESHKDE--IFQVQWSPHNETILASSG 302

Query: 242 TSRWNNRQVALWDQDNLSVPLMEEDL-DGSSGVLF 275
           T    +R++ +WD   +      ED  DG   +LF
Sbjct: 303 T----DRRLNVWDLSKIGEEQSPEDAEDGPPELLF 333



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 18/89 (20%), Positives = 39/89 (43%), Gaps = 7/89 (7%)

Query: 81  HRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK---QLLTRNLTAYRKELV----GHAR 133
           H+  +  V+W+P ++  +AS   D  + +W + K   +    +      EL+    GH  
Sbjct: 281 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTA 340

Query: 134 RVGLVEWHPTAANILFSAGYDYKVMIWNL 162
           ++    W+P    ++ S   D  + +W +
Sbjct: 341 KISDFSWNPNEPWVICSVSEDNIMQVWQM 369



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 12/37 (32%), Positives = 21/37 (56%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQL 116
           GH   + D  WNP + + I S SED  +++W + + +
Sbjct: 337 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENI 373


>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
           sapiens]
          Length = 424

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 57/215 (26%), Positives = 95/215 (44%), Gaps = 17/215 (7%)

Query: 68  TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
           +G+ +P   ++ GH+     + WNP     + S S+D TI +W I        +   +  
Sbjct: 163 SGECNPDL-RLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTI 221

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
             GH   V  V WH    ++  S   D K+MIW  DT+ +  + P  ++  H   +  +S
Sbjct: 222 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIW--DTRSNNTSKPSHSVDAHTAEVNCLS 279

Query: 188 FNTNGS-LLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFL-----GNLKKLMSTG 241
           FN     +LAT   D+ + + D R    L+  S++ H+    +F       N   L S+G
Sbjct: 280 FNPYSEFILATGSADKTVALWDLR-NLKLKLHSFESHKDE--IFQVQWSPHNETILASSG 336

Query: 242 TSRWNNRQVALWDQDNLSVPLMEEDL-DGSSGVLF 275
           T    +R++ +WD   +      ED  DG   +LF
Sbjct: 337 T----DRRLNVWDLSKIGEEQSPEDAEDGPPELLF 367



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 18/89 (20%), Positives = 39/89 (43%), Gaps = 7/89 (7%)

Query: 81  HRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK---QLLTRNLTAYRKELV----GHAR 133
           H+  +  V+W+P ++  +AS   D  + +W + K   +    +      EL+    GH  
Sbjct: 315 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTA 374

Query: 134 RVGLVEWHPTAANILFSAGYDYKVMIWNL 162
           ++    W+P    ++ S   D  + +W +
Sbjct: 375 KISDFSWNPNEPWVICSVSEDNIMQVWQM 403



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 12/37 (32%), Positives = 21/37 (56%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQL 116
           GH   + D  WNP + + I S SED  +++W + + +
Sbjct: 371 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENI 407


>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
           sapiens]
          Length = 425

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 57/215 (26%), Positives = 95/215 (44%), Gaps = 17/215 (7%)

Query: 68  TGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE 127
           +G+ +P   ++ GH+     + WNP     + S S+D TI +W I        +   +  
Sbjct: 164 SGECNPDL-RLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTI 222

Query: 128 LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMS 187
             GH   V  V WH    ++  S   D K+MIW  DT+ +  + P  ++  H   +  +S
Sbjct: 223 FTGHTAVVEDVSWHLLHESLFGSVADDQKLMIW--DTRSNNTSKPSHSVDAHTAEVNCLS 280

Query: 188 FNTNGS-LLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFL-----GNLKKLMSTG 241
           FN     +LAT   D+ + + D R    L+  S++ H+    +F       N   L S+G
Sbjct: 281 FNPYSEFILATGSADKTVALWDLR-NLKLKLHSFESHKDE--IFQVQWSPHNETILASSG 337

Query: 242 TSRWNNRQVALWDQDNLSVPLMEEDL-DGSSGVLF 275
           T    +R++ +WD   +      ED  DG   +LF
Sbjct: 338 T----DRRLNVWDLSKIGEEQSPEDAEDGPPELLF 368



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 18/89 (20%), Positives = 39/89 (43%), Gaps = 7/89 (7%)

Query: 81  HRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK---QLLTRNLTAYRKELV----GHAR 133
           H+  +  V+W+P ++  +AS   D  + +W + K   +    +      EL+    GH  
Sbjct: 316 HKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTA 375

Query: 134 RVGLVEWHPTAANILFSAGYDYKVMIWNL 162
           ++    W+P    ++ S   D  + +W +
Sbjct: 376 KISDFSWNPNEPWVICSVSEDNIMQVWQM 404



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 12/37 (32%), Positives = 21/37 (56%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQL 116
           GH   + D  WNP + + I S SED  +++W + + +
Sbjct: 372 GHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENI 408


>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
          Length = 589

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 54/204 (26%), Positives = 89/204 (43%), Gaps = 21/204 (10%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   V D+  +P+  +  AS S D T ++WS  +   T  L  Y     GH   V  V+
Sbjct: 382 GHAYPVWDLDISPYSLY-FASGSHDRTARLWSFDR---TYPLRIY----AGHLADVDCVK 433

Query: 140 WHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTC 199
           +HP + N L +   D  V +W+     SV        + H+  +LS++F+ NG  LA+  
Sbjct: 434 FHPNS-NYLATGSTDKTVRLWSAQQGNSV-----RLFTGHRGPVLSLAFSPNGKYLASAG 487

Query: 200 KDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMSTGTSRWNNRQVALWDQDNLS 259
           +D+++++ D  +GT+ +E        + + F  +   + S       +  V +WD  N  
Sbjct: 488 EDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASM----DNSVRVWDIRN-- 541

Query: 260 VPLMEEDLDGSSGVLFPFYDADTS 283
                   DGSS  L   Y    S
Sbjct: 542 -TYCSAPADGSSSELVGVYTGQMS 564



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 54/224 (24%), Positives = 100/224 (44%), Gaps = 27/224 (12%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH G V   ++   D   + SCSED +I+ W +       N   Y+    GHA  V  ++
Sbjct: 340 GHCGPVYSTRFLA-DSSGLLSCSEDMSIRYWDLGS---FTNTVLYQ----GHAYPVWDLD 391

Query: 140 WHPTAANILFSAG-YDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATT 198
             P   ++ F++G +D    +W+ D      T P+   + H   +  + F+ N + LAT 
Sbjct: 392 ISP--YSLYFASGSHDRTARLWSFDR-----TYPLRIYAGHLADVDCVKFHPNSNYLATG 444

Query: 199 CKDRKIRVIDPRAGTVLQEASYKGHRAS--KVLFLGNLKKLMSTGTSRWNNRQVALWDQD 256
             D+ +R+   + G  ++   + GHR     + F  N K L S G     ++++ LWD  
Sbjct: 445 STDKTVRLWSAQQGNSVR--LFTGHRGPVLSLAFSPNGKYLASAG----EDQRLKLWD-- 496

Query: 257 NLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEV 300
            L+   + ++L G +  +     +  S L      D ++R +++
Sbjct: 497 -LASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 539


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 36/147 (24%), Positives = 74/147 (50%), Gaps = 19/147 (12%)

Query: 81  HRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELV-GHARRVGLVE 139
           H+  + +  ++P D+ + A+CS+D T++IW          L  + + ++ GH   V  V+
Sbjct: 201 HKEAIREASFSPTDN-KFATCSDDGTVRIWDF--------LRCHEERILRGHGADVKCVD 251

Query: 140 WHPTAANILF-SAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATT 198
           WHPT   ++  S      +  W+  T +S     ++T+  H++ ++ +  N NG+ L T 
Sbjct: 252 WHPTKGLVVSGSKDSQQPIKFWDPKTGQS-----LATLHAHKNTVMEVKLNLNGNWLLTA 306

Query: 199 CKDRKIRVIDPRAGTVLQEAS-YKGHR 224
            +D   ++ D R   + +E   ++GH+
Sbjct: 307 SRDHLCKLFDIR--NLKEELQVFRGHK 331



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 30/121 (24%), Positives = 57/121 (47%), Gaps = 11/121 (9%)

Query: 81  HRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEW 140
           H+  V++VK N   ++ + + S D   K++ I      RNL    +   GH +    V W
Sbjct: 287 HKNTVMEVKLNLNGNW-LLTASRDHLCKLFDI------RNLKEELQVFRGHKKEATAVAW 339

Query: 141 HPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCK 200
           HP    +  S G D  ++ W++  ++ V    M+    H+ +I S++++  G +L +   
Sbjct: 340 HPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMA----HEGMIWSLAWHPLGHILCSGSN 395

Query: 201 D 201
           D
Sbjct: 396 D 396



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 21/85 (24%), Positives = 32/85 (37%), Gaps = 15/85 (17%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVG----HARRV 135
           GH+     V W+P  +   AS   D ++  W +             KE+ G    H   +
Sbjct: 329 GHKKEATAVAWHPVHEGLFASGGSDGSLLFWHV----------GVEKEVGGMEMAHEGMI 378

Query: 136 GLVEWHPTAANILFSAGYDYKVMIW 160
             + WHP   +IL S   D+    W
Sbjct: 379 WSLAWHP-LGHILCSGSNDHTSKFW 402


>gi|4757988 WD repeat domain 39 [Homo sapiens]
          Length = 339

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 35/127 (27%), Positives = 64/127 (50%), Gaps = 9/127 (7%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   V  V W P  +  +A+CS D ++ +W + ++     ++     L  H + V  V 
Sbjct: 103 GHENEVKSVAWAPSGNL-LATCSRDKSVWVWEVDEEDEYECVSV----LNSHTQDVKHVV 157

Query: 140 WHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTC 199
           WHP +  +L SA YD  V ++  +  + V     +T+  H+  + S++F+ +G  LA+  
Sbjct: 158 WHP-SQELLASASYDDTVKLYREEEDDWVC---CATLEGHESTVWSLAFDPSGQRLASCS 213

Query: 200 KDRKIRV 206
            DR +R+
Sbjct: 214 DDRTVRI 220



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 41/125 (32%), Positives = 59/125 (47%), Gaps = 25/125 (20%)

Query: 90  WNPFDDFEIASCSEDATIKIWS------IPKQLLTRNLTAYRKELVGHARRVGLVEWHPT 143
           WNP     +ASC  D  I+IW       I K +L+           GH R V  V W P 
Sbjct: 24  WNPAGTL-LASCGGDRRIRIWGTEGDSWICKSVLSE----------GHQRTVRKVAWSP- 71

Query: 144 AANILFSAGYDYKVMIW--NLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCKD 201
             N L SA +D    IW  N D  E V     +T+  H++ + S+++  +G+LLAT  +D
Sbjct: 72  CGNYLASASFDATTCIWKKNQDDFECV-----TTLEGHENEVKSVAWAPSGNLLATCSRD 126

Query: 202 RKIRV 206
           + + V
Sbjct: 127 KSVWV 131



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 9/104 (8%)

Query: 72  DPHYPKVCG----HRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK---QLLTRNLTAY 124
           DP +  +C     H   + D+ W         +C +DA       P    Q  T +LTA+
Sbjct: 238 DPSWKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTFSLTAH 297

Query: 125 RKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESV 168
             +   H++ V  V W+P    +L S   D +V  W     E +
Sbjct: 298 LHQ--AHSQDVNCVAWNPKEPGLLASCSDDGEVAFWKYQRPEGL 339



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 13/86 (15%)

Query: 32  TRSVHDNHFCAVNPHFIAVVTECAGGGAFLVI-------PLHQTGKLDPHYPKVCGHRGN 84
           +R+++D  +C +     A+ T C G  A  V        P   T  L  H  +   H  +
Sbjct: 252 SRTIYDIAWCQLTG---ALATAC-GDDAIRVFQEDPNSDPQQPTFSLTAHLHQA--HSQD 305

Query: 85  VLDVKWNPFDDFEIASCSEDATIKIW 110
           V  V WNP +   +ASCS+D  +  W
Sbjct: 306 VNCVAWNPKEPGLLASCSDDGEVAFW 331



 Score = 29.6 bits (65), Expect = 7.1
 Identities = 12/31 (38%), Positives = 19/31 (61%), Gaps = 1/31 (3%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIW 110
           GH   V  + ++P     +ASCS+D T++IW
Sbjct: 192 GHESTVWSLAFDPSGQ-RLASCSDDRTVRIW 221


>gi|113865883 WD repeat domain 38 [Homo sapiens]
          Length = 314

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 46/175 (26%), Positives = 83/175 (47%), Gaps = 18/175 (10%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH G V   +++P D    AS S D T+++W + +    R        L GH R V  V 
Sbjct: 61  GHTGPVKFCRFSP-DGHLFASASCDCTVRLWDVARAKCLR-------VLKGHQRSVETVS 112

Query: 140 WHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTC 199
           + P +   L S G+D +VM+W++ + +      +  +  H+D I S  F+   + LAT  
Sbjct: 113 FSPDSRQ-LASGGWDKRVMLWDVQSGQM-----LRLLVGHRDSIQSSDFSPTVNCLATGS 166

Query: 200 KDRKIRVIDPRAGT-VLQEASYKGHRASKVLFLGNLKKLMSTGTSRWNNRQVALW 253
            D  + + D R  T  +   + +GH A+      +   L+++G+  W ++ + +W
Sbjct: 167 WDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASGLLASGS--W-DKTIHIW 218



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 13/110 (11%)

Query: 98  IASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKV 157
           +AS S D TI IW      L         +L GH   V  + + P     L SAGY   V
Sbjct: 206 LASGSWDKTIHIWKPTTSSLLI-------QLKGHVTWVKSIAFSPDEL-WLASAGYSRMV 257

Query: 158 MIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCKDRKIRVI 207
            +W+ +T +      + T+    DV  + +F  +G +L +   D+  R I
Sbjct: 258 KVWDCNTGKC-----LETLKGVLDVAHTCAFTPDGKILVSGAADQTRRQI 302


>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
          Length = 323

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 31/135 (22%), Positives = 61/135 (45%), Gaps = 11/135 (8%)

Query: 81  HRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEW 140
           H+  +L   W  +++  + + + D +++ W +      RN+     EL+GH   +  V++
Sbjct: 197 HQAEILSCDWCKYNENLLVTGAVDCSLRGWDL------RNVRQPVFELLGHTYAIRRVKF 250

Query: 141 HPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCK 200
            P  A++L S  YD+ V  WN    +S+    + T+  H +    + F+         C 
Sbjct: 251 SPFHASVLASCSYDFTVRFWNFSKPDSL----LETVEHHTEFTCGLDFSLQSPTQVADCS 306

Query: 201 -DRKIRVIDPRAGTV 214
            D  I++ DP   T+
Sbjct: 307 WDETIKIYDPACLTI 321



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 13/132 (9%)

Query: 85  VLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEWHPT- 143
           + DV W+  ++  + +CS D ++++W   K      L  Y++    HA+ V  V+W  T 
Sbjct: 70  LFDVTWSENNEHVLITCSGDGSLQLWDTAK--AAGPLQVYKE----HAQEVYSVDWSQTR 123

Query: 144 AANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTN-GSLLATTCKDR 202
              ++ S  +D  V +W     +  +   + T   H+ +I S  ++ +     A+   D+
Sbjct: 124 GEQLVVSGSWDQTVKLW-----DPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQ 178

Query: 203 KIRVIDPRAGTV 214
            +R+ D +A  V
Sbjct: 179 TLRIWDVKAAGV 190



 Score = 33.9 bits (76), Expect = 0.37
 Identities = 14/38 (36%), Positives = 23/38 (60%)

Query: 77  KVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPK 114
           ++ GH   +  VK++PF    +ASCS D T++ W+  K
Sbjct: 237 ELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSK 274


>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
           sapiens]
          Length = 522

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 20/140 (14%)

Query: 80  GHRGNVLDVKWNPFD-------DFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHA 132
           GH  NV  + ++P         D  +ASC+ D ++K+WS+              ++ GH 
Sbjct: 271 GHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPV-------ADIEGHT 323

Query: 133 RRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNG 192
            RV  V WHP +   L +  YD    +W+L+ +E ++         H   +  ++F+ +G
Sbjct: 324 VRVARVMWHP-SGRFLGTTCYDRSWRLWDLEAQEEILHQ-----EGHSMGVYDIAFHQDG 377

Query: 193 SLLATTCKDRKIRVIDPRAG 212
           SL  T   D   RV D R G
Sbjct: 378 SLAGTGGLDAFGRVWDLRTG 397



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 30/127 (23%), Positives = 61/127 (48%), Gaps = 13/127 (10%)

Query: 80  GHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVE 139
           GH   +  + ++P + + IA+ S D T K+W + ++     + A++  + G       V+
Sbjct: 405 GHLKEIYGINFSP-NGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTG-------VK 456

Query: 140 WHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTC 199
           + P   N L +  YD    IW          SP+ T++ H+  ++ +  +++G L+AT  
Sbjct: 457 FEPIHGNFLLTGAYDNTAKIWTHPG-----WSPLKTLAGHEGKVMGLDISSDGQLIATCS 511

Query: 200 KDRKIRV 206
            DR  ++
Sbjct: 512 YDRTFKL 518


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,836,706
Number of Sequences: 37866
Number of extensions: 1033580
Number of successful extensions: 4141
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 142
Number of HSP's that attempted gapping in prelim test: 3342
Number of HSP's gapped (non-prelim): 657
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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