BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] (693 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] 1393 0.0 gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] 1393 0.0 gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens] 841 0.0 gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 663 0.0 gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 107 4e-23 gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 107 5e-23 gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo... 106 6e-23 gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 104 2e-22 gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 104 2e-22 gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 103 7e-22 gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 103 7e-22 gi|114688046 TBC1 domain family, member 4 [Homo sapiens] 99 2e-20 gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 95 2e-19 gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 92 2e-18 gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member... 89 1e-17 gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 87 7e-17 gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 86 2e-16 gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 83 1e-15 gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 83 1e-15 gi|226693407 TBC1 domain family, member 3H [Homo sapiens] 77 4e-14 gi|157502205 TBC1 domain family, member 3G [Homo sapiens] 77 4e-14 gi|183583565 TBC1 domain family, member 3 [Homo sapiens] 77 5e-14 gi|183583567 TBC1 domain family, member 3E [Homo sapiens] 77 5e-14 gi|183583563 TBC1 domain family, member 3D [Homo sapiens] 77 5e-14 gi|14149985 TBC1 domain family, member 3F [Homo sapiens] 77 7e-14 gi|90577185 TBC1 domain family member 3C [Homo sapiens] 74 3e-13 gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 73 8e-13 gi|149999613 TBC1 domain family, member 3B [Homo sapiens] 73 1e-12 gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 72 2e-12 gi|222352143 TBC1 domain family, member 2 [Homo sapiens] 67 6e-11 >gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] Length = 693 Score = 1393 bits (3606), Expect = 0.0 Identities = 693/693 (100%), Positives = 693/693 (100%) Query: 1 MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS 60 MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS Sbjct: 1 MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS 60 Query: 61 LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER 120 LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER Sbjct: 61 LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER 120 Query: 121 EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL 180 EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL Sbjct: 121 EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL 180 Query: 181 VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA 240 VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA Sbjct: 181 VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA 240 Query: 241 RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV 300 RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV Sbjct: 241 RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV 300 Query: 301 RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL 360 RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL Sbjct: 301 RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL 360 Query: 361 EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN 420 EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN Sbjct: 361 EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN 420 Query: 421 ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF 480 ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF Sbjct: 421 ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF 480 Query: 481 QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM 540 QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM Sbjct: 481 QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM 540 Query: 541 AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA 600 AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA Sbjct: 541 AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA 600 Query: 601 CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT 660 CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT Sbjct: 601 CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT 660 Query: 661 IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 693 IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH Sbjct: 661 IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 693 >gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] Length = 693 Score = 1393 bits (3606), Expect = 0.0 Identities = 693/693 (100%), Positives = 693/693 (100%) Query: 1 MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS 60 MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS Sbjct: 1 MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS 60 Query: 61 LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER 120 LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER Sbjct: 61 LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER 120 Query: 121 EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL 180 EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL Sbjct: 121 EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL 180 Query: 181 VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA 240 VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA Sbjct: 181 VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA 240 Query: 241 RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV 300 RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV Sbjct: 241 RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV 300 Query: 301 RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL 360 RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL Sbjct: 301 RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL 360 Query: 361 EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN 420 EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN Sbjct: 361 EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN 420 Query: 421 ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF 480 ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF Sbjct: 421 ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF 480 Query: 481 QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM 540 QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM Sbjct: 481 QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM 540 Query: 541 AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA 600 AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA Sbjct: 541 AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA 600 Query: 601 CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT 660 CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT Sbjct: 601 CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT 660 Query: 661 IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 693 IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH Sbjct: 661 IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 693 >gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens] Length = 413 Score = 841 bits (2173), Expect = 0.0 Identities = 412/412 (100%), Positives = 412/412 (100%) Query: 282 EYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEM 341 EYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEM Sbjct: 2 EYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEM 61 Query: 342 VVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQG 401 VVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQG Sbjct: 62 VVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQG 121 Query: 402 IPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREA 461 IPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREA Sbjct: 122 IPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREA 181 Query: 462 SLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL 521 SLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL Sbjct: 182 SLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL 241 Query: 522 DTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDI 581 DTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDI Sbjct: 242 DTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDI 301 Query: 582 YLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQF 641 YLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQF Sbjct: 302 YLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQF 361 Query: 642 LTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 693 LTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH Sbjct: 362 LTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 413 >gi|148806902 TBC1 domain family, member 12 [Homo sapiens] Length = 775 Score = 663 bits (1710), Expect = 0.0 Identities = 325/462 (70%), Positives = 387/462 (83%), Gaps = 5/462 (1%) Query: 233 GPFSNFFARNLLARK-QSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPS 291 G F++FF RNL ++ + + H+ GWKLFGK P REN QK SK IQ+EYE + GR Sbjct: 316 GGFADFFTRNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTC 375 Query: 292 KPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELK 351 KPP P+ + RKN +FEPLSTTALILEDRP+NLPAK EEA +HRQ+Y+EMV +AKKRE+K Sbjct: 376 KPP-PQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIK 434 Query: 352 EAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVW 411 EA +RK+ ++ER + EE+I +A++ W NEILPNWE M +R+VR+LWWQG+PPSVRGKVW Sbjct: 435 EAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVW 494 Query: 412 SLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDIS 471 SLA+GNELNIT EL++I L+RAKERW+S S SE N+ G S ADREASLELIKLDIS Sbjct: 495 SLAVGNELNITPELYEIFLSRAKERWKSFSETSSE--NDTEGVSVADREASLELIKLDIS 552 Query: 472 RTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFS 531 RTFP+L IFQ+GGPYHD+LHSILGAYTCYRPDVGYVQGMSFIAAVLILNL+ ADAFIAF+ Sbjct: 553 RTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFA 612 Query: 532 NLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLY 591 NLLNKPCQ+AFFRVDH +ML YFA FEVFFEENL KLF HFK +LTPDIYLIDWIFTLY Sbjct: 613 NLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLY 672 Query: 592 SKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPA 651 SKSLPLDLACR+WDVFCRDGEEFLFRT LGIL+L+EDIL +MDFIH+AQFLT+LPED+ + Sbjct: 673 SKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITS 732 Query: 652 EELFASIATIQMQSRNKKWAQVLTALQKDSREMEK-GSPSLR 692 E+LF+ IA IQMQ+ KKW QV ++ KD +E +K SP+L+ Sbjct: 733 EKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPALK 774 >gi|68299759 ecotropic viral integration site 5 [Homo sapiens] Length = 810 Score = 107 bits (267), Expect = 4e-23 Identities = 97/412 (23%), Positives = 178/412 (43%), Gaps = 49/412 (11%) Query: 291 SKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKREL 350 S+ SP ++ LST AL P+ L E K +Q + +K Sbjct: 47 SQVASPSTSLHTTSSSTTLSTPALS-PSSPSQLSPDDLELLAKLEEQNRLLETDSKSLRS 105 Query: 351 KEAQRRKK--QLEERCRVEESIGN----AVLTWNNEILPNWETMWCSRK--VRDLWWQGI 402 RR L ++ + + + W I+ WE + ++ V++L +GI Sbjct: 106 VNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGR-IVNEWEDVRKKKEKQVKELVHKGI 164 Query: 403 PPSVRGKVWSLAIGNELNITHELFDICLARA---KERWRSLSTGGSEVENEDAGFSAADR 459 P R VW L +C A++ K+++ L S E Sbjct: 165 PHHFRAIVWQL--------------LCSAQSMPIKDQYSELLKMTSPCE----------- 199 Query: 460 EASLELIKLDISRTFPNLCIFQQGGPY-HDMLHSILGAYTCYRPDVGYVQGMSFIAAVLI 518 +LI+ DI+RT+P F++ ++L +++ AY+ +VGY QG +FI +L+ Sbjct: 200 ----KLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLL 255 Query: 519 LNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLT 578 + + +AF F L+ F+ + FE +E+LP+LF HF+ + Sbjct: 256 MQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQSQSFH 315 Query: 579 PDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHM 638 +Y W T++ + PL +A RI+D+F +G E +FR L +L++ + L ++D M Sbjct: 316 TSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGM 375 Query: 639 AQFLTRLP----EDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEK 686 Q ++ + +P + + A+ + KK + T ++ ++EME+ Sbjct: 376 LQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIK--TKEMEE 425 >gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] Length = 1069 Score = 107 bits (266), Expect = 5e-23 Identities = 93/361 (25%), Positives = 147/361 (40%), Gaps = 29/361 (8%) Query: 297 KQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRR 356 KQ RKN L E + + + + V+ + + +E Sbjct: 460 KQRERKNNTDTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDND 519 Query: 357 KKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSR--KVRDLWWQGIPPSVRGKVWSLA 414 + L V + +L E+L W R ++ L G+P ++RG+VW L Sbjct: 520 EPLLSGSGDVSKECAEKILETWGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLL 579 Query: 415 IGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTF 474 G N E++R L T S ++ I DI+RTF Sbjct: 580 AGCHNN----------DHLVEKYRILITKESPQDSA---------------ITRDINRTF 614 Query: 475 PNLCIFQQ-GGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNL 533 P F+ GG D L+ I AY+ Y ++GY QG SF+AAVL+L++ AF + Sbjct: 615 PAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKI 674 Query: 534 LNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSK 593 + F+ + + F E +E +P L+ HF +L +Y W TL++ Sbjct: 675 MFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTA 734 Query: 594 SLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFL-TRLPEDLPAE 652 PL + I D+ +G +F ALG+LK +D L DF +F +LP+ +E Sbjct: 735 KFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSE 794 Query: 653 E 653 E Sbjct: 795 E 795 >gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo sapiens] Length = 815 Score = 106 bits (265), Expect = 6e-23 Identities = 82/278 (29%), Positives = 124/278 (44%), Gaps = 29/278 (10%) Query: 380 EILPNWETMWCSRK--VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERW 437 E+L W + +R + L G+P ++R +VW L G N +R+ Sbjct: 515 ELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDN----------QAMLDRY 564 Query: 438 RSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ-GGPYHDMLHSILGA 496 R L T S E+ +I DI RTFP F+ GG + L+ I A Sbjct: 565 RILITKDSAQES---------------VITRDIHRTFPAHDYFKDTGGDGQESLYKICKA 609 Query: 497 YTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAA 556 Y+ Y D+GY QG SF+AAVL+L++ AF ++ +R + + F Sbjct: 610 YSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQ 669 Query: 557 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 616 E +E LP L +HF NL +Y W TL++ PL + I D+ +G +F Sbjct: 670 LERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIF 729 Query: 617 RTALGILKLFEDILTKMDFIHMAQFL-TRLPEDLPAEE 653 AL +LK ++ L + DF +F +LP+ AEE Sbjct: 730 HVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEE 767 >gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] Length = 828 Score = 104 bits (260), Expect = 2e-22 Identities = 84/298 (28%), Positives = 134/298 (44%), Gaps = 26/298 (8%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 ++L WE + K ++GIP +RG+VW+L + + + KE R Sbjct: 79 KMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLE-------------IPKMKEETRD 125 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQG-GPYHDMLHSILGAYT 498 L S++++ G S R+ I LD++RTF + +F+ G L +L AY+ Sbjct: 126 LY---SKLKHRARGCSPDIRQ-----IDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYS 177 Query: 499 CYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKP--CQMAFFRVDHGLMLTYFAA 556 Y +VGY QGMS I A+L++ ++ DAF A L + P FF +L + Sbjct: 178 IYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEH 237 Query: 557 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 616 E + L KL H + Y + W F + P L RIWD++ +GE L Sbjct: 238 HEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLT 297 Query: 617 RTALGILKLFEDILTKMDFIHMAQFLTR-LPEDLPAEELFASIATIQMQSRNKKWAQV 673 + ILKL + L K+ + +F L +D E+ F I +Q+ K A++ Sbjct: 298 AMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFV-IEQLQISMTELKRAKL 354 >gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] Length = 845 Score = 104 bits (260), Expect = 2e-22 Identities = 84/298 (28%), Positives = 134/298 (44%), Gaps = 26/298 (8%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 ++L WE + K ++GIP +RG+VW+L + + + KE R Sbjct: 96 KMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLE-------------IPKMKEETRD 142 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQG-GPYHDMLHSILGAYT 498 L S++++ G S R+ I LD++RTF + +F+ G L +L AY+ Sbjct: 143 LY---SKLKHRARGCSPDIRQ-----IDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYS 194 Query: 499 CYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKP--CQMAFFRVDHGLMLTYFAA 556 Y +VGY QGMS I A+L++ ++ DAF A L + P FF +L + Sbjct: 195 IYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEH 254 Query: 557 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 616 E + L KL H + Y + W F + P L RIWD++ +GE L Sbjct: 255 HEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLT 314 Query: 617 RTALGILKLFEDILTKMDFIHMAQFLTR-LPEDLPAEELFASIATIQMQSRNKKWAQV 673 + ILKL + L K+ + +F L +D E+ F I +Q+ K A++ Sbjct: 315 AMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFV-IEQLQISMTELKRAKL 371 >gi|229577000 ecotropic viral integration site 5-like isoform 1 [Homo sapiens] Length = 805 Score = 103 bits (256), Expect = 7e-22 Identities = 84/316 (26%), Positives = 142/316 (44%), Gaps = 41/316 (12%) Query: 381 ILPNWETMWCSRK---VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLAR---AK 434 I WE W RK +++L +GIP R VW L +C A K Sbjct: 93 IANEWEE-WRRRKEKLLKELIRKGIPHHFRAIVWQL--------------LCSATDMPVK 137 Query: 435 ERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSI 493 ++ L S E +LI+ DI+RT+P F+ Q ++L ++ Sbjct: 138 NQYSELLKMSSPCE---------------KLIRRDIARTYPEHEFFKGQDSLGQEVLFNV 182 Query: 494 LGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTY 553 + AY+ +VGY QG +FI +L++ + +AF F L+ + F+ + Sbjct: 183 MKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLC 242 Query: 554 FAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEE 613 FE +E LP L HF+ + +Y W TL+ + PL +A R++D+F +G E Sbjct: 243 IYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLE 302 Query: 614 FLFRTALGILKLFEDILTKMDFIHMAQFLTR-LPE--DLPAEELFASIATIQMQSRNKKW 670 +FR L +L++ + L ++D M+Q+ R +P D ++L ++ + K Sbjct: 303 IVFRVGLALLQVNQAELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKR 362 Query: 671 AQVLTALQKDSREMEK 686 + A K S+EME+ Sbjct: 363 LEKEYAAMK-SKEMEE 377 >gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo sapiens] Length = 794 Score = 103 bits (256), Expect = 7e-22 Identities = 84/316 (26%), Positives = 142/316 (44%), Gaps = 41/316 (12%) Query: 381 ILPNWETMWCSRK---VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLAR---AK 434 I WE W RK +++L +GIP R VW L +C A K Sbjct: 93 IANEWEE-WRRRKEKLLKELIRKGIPHHFRAIVWQL--------------LCSATDMPVK 137 Query: 435 ERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSI 493 ++ L S E +LI+ DI+RT+P F+ Q ++L ++ Sbjct: 138 NQYSELLKMSSPCE---------------KLIRRDIARTYPEHEFFKGQDSLGQEVLFNV 182 Query: 494 LGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTY 553 + AY+ +VGY QG +FI +L++ + +AF F L+ + F+ + Sbjct: 183 MKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLC 242 Query: 554 FAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEE 613 FE +E LP L HF+ + +Y W TL+ + PL +A R++D+F +G E Sbjct: 243 IYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLE 302 Query: 614 FLFRTALGILKLFEDILTKMDFIHMAQFLTR-LPE--DLPAEELFASIATIQMQSRNKKW 670 +FR L +L++ + L ++D M+Q+ R +P D ++L ++ + K Sbjct: 303 IVFRVGLALLQVNQAELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKR 362 Query: 671 AQVLTALQKDSREMEK 686 + A K S+EME+ Sbjct: 363 LEKEYAAMK-SKEMEE 377 >gi|114688046 TBC1 domain family, member 4 [Homo sapiens] Length = 1298 Score = 98.6 bits (244), Expect = 2e-20 Identities = 76/325 (23%), Positives = 146/325 (44%), Gaps = 28/325 (8%) Query: 335 RQQYEEMVVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRK- 393 R + E ++A + EL ++++ K EE ++ + ++TW+ ++L + C + Sbjct: 855 RMEKENQKLEASRDEL-QSRKVKLDYEEVGACQKEV---LITWDKKLLNCRAKIRCDMED 910 Query: 394 VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAG 453 + L +G+P S RG++W + + + H L ++ + D Sbjct: 911 IHTLLKEGVPKSRRGEIWQF-LALQYRLRHRL------------------PNKQQPPDIS 951 Query: 454 FSAADRE--ASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSILGAYTCYRPDVGYVQGM 510 + ++ A I +D+ RTFP F Q GP L ++L AY+ +VGY QG+ Sbjct: 952 YKELLKQLTAQQHAILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEVGYCQGI 1011 Query: 511 SFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFA 570 SF+A VL+L++ AF L+ +R D + + L+ Sbjct: 1012 SFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYN 1071 Query: 571 HFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDIL 630 H ++N ++P +Y W TL++ L R++D+ G E +F+ AL +L E ++ Sbjct: 1072 HLEENEISPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLSSQETLI 1131 Query: 631 TKMD-FIHMAQFLTRLPEDLPAEEL 654 + + F ++ +FL D+ E+ Sbjct: 1132 MECESFENIVEFLKNTLPDMNTSEM 1156 >gi|13994322 TBC1 domain family, member 10A [Homo sapiens] Length = 508 Score = 95.1 bits (235), Expect = 2e-19 Identities = 63/251 (25%), Positives = 113/251 (45%), Gaps = 32/251 (12%) Query: 380 EILPNWETMWCSR--KVRDLWWQGIPPSVRGKVWSLAIGNELNITH---ELFDICLARAK 434 ++L NW+ + K+R +GIPPS+RG+ W G ++ + + ++ ++ Sbjct: 88 DMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGD 147 Query: 435 ERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF-QQGGPYHDMLHSI 493 +W L++I+ D+ R FP +F +GG L + Sbjct: 148 PKW-------------------------LDVIERDLHRQFPFHEMFVSRGGHGQQDLFRV 182 Query: 494 LGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTY 553 L AYT YRP+ GY Q + IAAVL++++ AF + K + + L Sbjct: 183 LKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLDG 242 Query: 554 FAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEE 613 F + ++ P H + + P +Y+ +W +S++LP R+WD+F +G + Sbjct: 243 EILFSLL-QKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVK 301 Query: 614 FLFRTALGILK 624 +FR L +LK Sbjct: 302 IIFRVGLVLLK 312 >gi|167614488 TBC1 domain family, member 10B [Homo sapiens] Length = 808 Score = 91.7 bits (226), Expect = 2e-18 Identities = 69/256 (26%), Positives = 113/256 (44%), Gaps = 42/256 (16%) Query: 380 EILPNWETMWCSR---KVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKER 436 ++ NW+ W SR KV+ +GIP S+R K W Sbjct: 337 DMFSNWDK-WLSRRFQKVKLRCRKGIPSSLRAKAWQY----------------------- 372 Query: 437 WRSLSTGGSEVENEDAGFSAADREAS----LELIKLDISRTFPNLCIFQ-QGGPYHDMLH 491 LS +E F +R L++I+ D+ R FP +F +GG L+ Sbjct: 373 ---LSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLY 429 Query: 492 SILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLML 551 IL AYT YRPD GY Q + +AAVL++++ AF + +K + + L Sbjct: 430 RILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQL 489 Query: 552 TYFAAFEVFF---EENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFC 608 E+FF P H ++ + P +Y+ +W +++++LP R+WD+F Sbjct: 490 DG----EIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFF 545 Query: 609 RDGEEFLFRTALGILK 624 +G + +FR AL +L+ Sbjct: 546 CEGVKIIFRVALVLLR 561 >gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 [Homo sapiens] Length = 1168 Score = 89.4 bits (220), Expect = 1e-17 Identities = 76/356 (21%), Positives = 148/356 (41%), Gaps = 43/356 (12%) Query: 305 DFEPLSTTALILEDRPANLPAKPAEEAQKH-RQQYEEMVVQAKKRELKEAQRRKKQLEER 363 + P S + ED P P + + + R+ +++ ++Q E + +K Q E Sbjct: 690 ELPPRSPLEPVCEDGPFGPPPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASEN 749 Query: 364 CRVEESIG---NAVLTWNNEILPNWETMWCS----------RKVRDLWWQGIPPSVRGKV 410 + + + + E+ WE M + K+ QG+P RG++ Sbjct: 750 DLLNKRLKLDYEEITPCLKEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEI 809 Query: 411 WSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLE--LIKL 468 W + + ++ H+ S+ + +D + ++ + + I + Sbjct: 810 WKF-LAEQFHLKHQF------------------PSKQQPKDVPYKELLKQLTSQQHAILI 850 Query: 469 DISRTFPNLCIFQ-QGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAF 527 D+ RTFP F Q G L++IL AY+ +VGY QG+SF+A +L+L++ +AF Sbjct: 851 DLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAF 910 Query: 528 IAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWI 587 L+ +R D ++ + L+ H +++ + P +Y W Sbjct: 911 KMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWF 970 Query: 588 FTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGIL-------KLFEDILTKMDFI 636 T+++ PL R++D+ G E +F+ AL +L E++ T +DFI Sbjct: 971 LTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHKPLILQHENLETIVDFI 1026 >gi|38348348 TBC1 domain family, member 10C [Homo sapiens] Length = 446 Score = 86.7 bits (213), Expect = 7e-17 Identities = 64/253 (25%), Positives = 110/253 (43%), Gaps = 34/253 (13%) Query: 380 EILPNWETMWCSR--KVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERW 437 E+ +WE R KV+ +GIP ++R + W L G +C + + Sbjct: 69 EMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAH---------VCQKNSPGTY 119 Query: 438 RSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFP--NLCIFQQGGPYHDMLHSILG 495 + L+ + + +E I D+ R FP + + QG +L +L Sbjct: 120 QELAEAPGDPQ-------------WMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQ-VLK 165 Query: 496 AYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM---AFFRVDHGLMLT 552 AYT YRP+ GY Q +AAVL+++L +AF + C++ ++ + Sbjct: 166 AYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQI----CEVYLPGYYGPHMEAVRL 221 Query: 553 YFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGE 612 F LP + H ++ + P +YL +W L+++SLP R+WD F +G Sbjct: 222 DAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGA 281 Query: 613 EFLFRTALGILKL 625 LFR L +++L Sbjct: 282 RVLFRVGLTLVRL 294 >gi|29648315 small G protein signaling modulator 3 [Homo sapiens] Length = 749 Score = 85.5 bits (210), Expect = 2e-16 Identities = 69/271 (25%), Positives = 116/271 (42%), Gaps = 22/271 (8%) Query: 391 SRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENE 450 S K+R L GIP +R ++W G A K+R LS E Sbjct: 104 SEKLRSLVLAGIPHGMRPQLWMRLSG--------------ALQKKRNSELSY------RE 143 Query: 451 DAGFSAADREASLELIKLDISRTFP-NLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQG 509 S+ D + + I+ D+ RT P N C G L +L A P++GY QG Sbjct: 144 IVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQG 203 Query: 510 MSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLF 569 +AA L+L L+ DAF S ++ ++F + T + LP+L Sbjct: 204 TGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLD 263 Query: 570 AHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKL-FED 628 +++++ + + W T ++ + + L RIWD+F +G LF+ LG+L L E+ Sbjct: 264 KLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEE 323 Query: 629 ILTKMDFIHMAQFLTRLPEDLPAEELFASIA 659 ++ + + L+ +P + EL +A Sbjct: 324 LIQSENSASIFNTLSDIPSQMEDAELLLGVA 354 >gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] Length = 963 Score = 82.8 bits (203), Expect = 1e-15 Identities = 64/255 (25%), Positives = 107/255 (41%), Gaps = 34/255 (13%) Query: 388 MWCSRKVRDLWWQGIPPSVRGKVWSLAIGNEL-----NITHELFDICLARAKERWRSLST 442 M CS ++++L GIP R KVW + N F L +A E+ S Sbjct: 649 MMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPAS- 707 Query: 443 GGSEVENEDAGFSAADREASLELIKLDISRTFPN----LCIFQQGGPYHDMLHSILGAYT 498 + I+LD+ RT PN C +G L ++L A++ Sbjct: 708 ---------------------KQIELDLLRTLPNNKHYSCPTSEG---IQKLRNVLLAFS 743 Query: 499 CYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFE 558 PD+GY QG++ + AV +L L+ DAF ++ ++ F Sbjct: 744 WRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFR 803 Query: 559 VFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRT 618 E LP+L HF++ + + +W ++ S+ D+ +IWD F +G + +FR Sbjct: 804 DLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRF 863 Query: 619 ALGILKLFEDILTKM 633 AL + K E+ + K+ Sbjct: 864 ALALFKYKEEEILKL 878 >gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] Length = 914 Score = 82.8 bits (203), Expect = 1e-15 Identities = 64/255 (25%), Positives = 107/255 (41%), Gaps = 34/255 (13%) Query: 388 MWCSRKVRDLWWQGIPPSVRGKVWSLAIGNEL-----NITHELFDICLARAKERWRSLST 442 M CS ++++L GIP R KVW + N F L +A E+ S Sbjct: 649 MMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPAS- 707 Query: 443 GGSEVENEDAGFSAADREASLELIKLDISRTFPN----LCIFQQGGPYHDMLHSILGAYT 498 + I+LD+ RT PN C +G L ++L A++ Sbjct: 708 ---------------------KQIELDLLRTLPNNKHYSCPTSEG---IQKLRNVLLAFS 743 Query: 499 CYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFE 558 PD+GY QG++ + AV +L L+ DAF ++ ++ F Sbjct: 744 WRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFR 803 Query: 559 VFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRT 618 E LP+L HF++ + + +W ++ S+ D+ +IWD F +G + +FR Sbjct: 804 DLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRF 863 Query: 619 ALGILKLFEDILTKM 633 AL + K E+ + K+ Sbjct: 864 ALALFKYKEEEILKL 878 >gi|226693407 TBC1 domain family, member 3H [Homo sapiens] Length = 549 Score = 77.4 bits (189), Expect = 4e-14 Identities = 70/257 (27%), Positives = 112/257 (43%), Gaps = 26/257 (10%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 ++L +WE SRK+ D ++G+P ++RG +WS+ LNI E + Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497 + G ++ E S+ ++ I DIS T F+ G ++LH +L AY Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL-AY 177 Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555 Y P+VGY + +S IAA+ +L L DAF A LL + F + G + Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237 Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615 E + PK H K +L + + + + L L R+WDV+ +GE+ L Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297 Query: 616 FRTALGILKLFEDILTK 632 K+ + LTK Sbjct: 298 MPITRIAFKVQQKRLTK 314 >gi|157502205 TBC1 domain family, member 3G [Homo sapiens] Length = 549 Score = 77.4 bits (189), Expect = 4e-14 Identities = 70/257 (27%), Positives = 112/257 (43%), Gaps = 26/257 (10%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 ++L +WE SRK+ D ++G+P ++RG +WS+ LNI E + Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497 + G ++ E S+ ++ I DIS T F+ G ++LH +L AY Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL-AY 177 Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555 Y P+VGY + +S IAA+ +L L DAF A LL + F + G + Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237 Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615 E + PK H K +L + + + + L L R+WDV+ +GE+ L Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297 Query: 616 FRTALGILKLFEDILTK 632 K+ + LTK Sbjct: 298 MPITRIAFKVQQKRLTK 314 >gi|183583565 TBC1 domain family, member 3 [Homo sapiens] Length = 549 Score = 77.0 bits (188), Expect = 5e-14 Identities = 69/257 (26%), Positives = 112/257 (43%), Gaps = 26/257 (10%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 ++L +WE SRK+ D ++G+P ++RG +WS+ LNI E + Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497 + G ++ E S+ ++ I D+S T F+ G ++LH +L AY Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL-AY 177 Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555 Y P+VGY + +S IAA+ +L L DAF A LL + F + G + Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237 Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615 E + PK H K +L + + + + L L R+WDV+ +GE+ L Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297 Query: 616 FRTALGILKLFEDILTK 632 K+ + LTK Sbjct: 298 MPITRIAFKVQQKRLTK 314 >gi|183583567 TBC1 domain family, member 3E [Homo sapiens] Length = 549 Score = 77.0 bits (188), Expect = 5e-14 Identities = 69/257 (26%), Positives = 112/257 (43%), Gaps = 26/257 (10%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 ++L +WE SRK+ D ++G+P ++RG +WS+ LNI E + Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497 + G ++ E S+ ++ I D+S T F+ G ++LH +L AY Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL-AY 177 Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555 Y P+VGY + +S IAA+ +L L DAF A LL + F + G + Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237 Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615 E + PK H K +L + + + + L L R+WDV+ +GE+ L Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297 Query: 616 FRTALGILKLFEDILTK 632 K+ + LTK Sbjct: 298 MPITRIAFKVQQKRLTK 314 >gi|183583563 TBC1 domain family, member 3D [Homo sapiens] Length = 549 Score = 77.0 bits (188), Expect = 5e-14 Identities = 69/257 (26%), Positives = 112/257 (43%), Gaps = 26/257 (10%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 ++L +WE SRK+ D ++G+P ++RG +WS+ LNI E + Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497 + G ++ E S+ ++ I D+S T F+ G ++LH +L AY Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL-AY 177 Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555 Y P+VGY + +S IAA+ +L L DAF A LL + F + G + Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237 Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615 E + PK H K +L + + + + L L R+WDV+ +GE+ L Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297 Query: 616 FRTALGILKLFEDILTK 632 K+ + LTK Sbjct: 298 MPITRIAFKVQQKRLTK 314 >gi|14149985 TBC1 domain family, member 3F [Homo sapiens] Length = 549 Score = 76.6 bits (187), Expect = 7e-14 Identities = 66/257 (25%), Positives = 110/257 (42%), Gaps = 26/257 (10%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 ++L +WE SRK+ D ++G+P ++RG +WS+ + E + Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTE-----------------EMKL 122 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497 + G ++ E S+ ++ I D+S T F+ G ++LH +L AY Sbjct: 123 KNPGRYQIMKEKGKKSSEH----IQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL-AY 177 Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555 Y P+VGY + +S IAA+ +L L DAF A LL + F + G + Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237 Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615 E + PK H K +L + + + + L L R+WDV+ +GE+ L Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297 Query: 616 FRTALGILKLFEDILTK 632 K+ + LTK Sbjct: 298 MPITRIAFKVQQKRLTK 314 >gi|90577185 TBC1 domain family member 3C [Homo sapiens] Length = 549 Score = 74.3 bits (181), Expect = 3e-13 Identities = 69/257 (26%), Positives = 111/257 (43%), Gaps = 26/257 (10%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 ++L +WE SRK+ D ++G+P ++RG +WS+ LNI E + Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497 + G ++ E S+ ++ I DIS T F+ G ++LH +L AY Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL-AY 177 Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555 Y P+VGY + +S IAA+ +L L DAF A LL + F + G + Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237 Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615 E + K H K +L + + + + L L R+WDV+ +GE+ L Sbjct: 238 QQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297 Query: 616 FRTALGILKLFEDILTK 632 K+ + LTK Sbjct: 298 MPITRIAFKVQQKRLTK 314 >gi|38570101 TBC1 domain family, member 8B (with GRAM domain) isoform a [Homo sapiens] Length = 1120 Score = 73.2 bits (178), Expect = 8e-13 Identities = 67/261 (25%), Positives = 110/261 (42%), Gaps = 28/261 (10%) Query: 387 TMWCSRKVRDLWWQGIPPSVRGKVWSLAIG--NELNITHELFDICLARAKERWRSLSTGG 444 +M+ ++K RDL +GIP ++RG++W L G N++ + + Sbjct: 473 SMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYY------------------ 514 Query: 445 SEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDV 504 +EV + G + E I+ D+ R+ P FQ L +L AY P + Sbjct: 515 TEVVEQSLGTC----NLATEEIERDLRRSLPEHPAFQSDTGI-SALRRVLTAYAYRNPKI 569 Query: 505 GYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEEN 564 GY Q M+ + +VL+L +AF + + F R G ++ A FE ++ Sbjct: 570 GYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQ-AVFEELIRDH 628 Query: 565 LPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILK 624 LP+L H + L W TL+ LP++ A + D F DG + + + L IL Sbjct: 629 LPQLTEHMTDMTFFSSVSL-SWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILD 687 Query: 625 L-FEDILTKMDFIHMAQFLTR 644 + +LT D L R Sbjct: 688 YNLDKLLTCKDDAEAVTALNR 708 >gi|149999613 TBC1 domain family, member 3B [Homo sapiens] Length = 549 Score = 72.8 bits (177), Expect = 1e-12 Identities = 68/257 (26%), Positives = 110/257 (42%), Gaps = 26/257 (10%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 ++L +WE SRK+ D ++G+P ++RG +WS+ LNI E + Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497 + G ++ E S+ ++ I DIS T F+ G ++LH +L AY Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL-AY 177 Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555 Y P+VGY + +S IAA+ +L DAF A LL + F + G + Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYFPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237 Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615 E + K H K +L + + + + L L R+WDV+ +GE+ L Sbjct: 238 QQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297 Query: 616 FRTALGILKLFEDILTK 632 K+ + LTK Sbjct: 298 MPITRIAFKVQQKRLTK 314 >gi|109638751 ubiquitin specific protease 6 [Homo sapiens] Length = 1406 Score = 72.0 bits (175), Expect = 2e-12 Identities = 71/256 (27%), Positives = 108/256 (42%), Gaps = 24/256 (9%) Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439 E+L WET S K+ D ++GIP ++RG VWS+ LNI + + Sbjct: 79 EMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVL----LNI-------------QEIKL 121 Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSILGAYT 498 + G ++ E S+ + I LD+ T N F+ + G L IL AY+ Sbjct: 122 KNPGRYQIMKERGKRSS----EHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYS 177 Query: 499 CYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFAA 556 Y P+VGY + +S I A+ +L L DAF A LL + F + G + Sbjct: 178 EYNPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQ 237 Query: 557 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 616 E ++ PK H K L + + + L L R+WDV+ +GE+ L Sbjct: 238 QEHVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLM 297 Query: 617 RTALGILKLFEDILTK 632 LK+ + L K Sbjct: 298 PITSIALKVQQKRLMK 313 >gi|222352143 TBC1 domain family, member 2 [Homo sapiens] Length = 917 Score = 67.0 bits (162), Expect = 6e-11 Identities = 64/297 (21%), Positives = 121/297 (40%), Gaps = 32/297 (10%) Query: 391 SRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENE 450 S +++ L G+P R +VW + L + H L T G E Sbjct: 615 SAELKQLLRAGVPREHRPRVWRWLV--HLRVQH----------------LHTPGCYQELL 656 Query: 451 DAGFSAADREASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSILGAYTCYRPDVGYVQG 509 G A + I+LD++RTFPN F + D L +L A++ P +GY QG Sbjct: 657 SRG--QAREHPAARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQG 714 Query: 510 MSFIAAVLILNLDTAD-AFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKL 568 ++ +AA+ +L L+ + AF ++ ++ + E LP+L Sbjct: 715 LNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRL 774 Query: 569 FAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFED 628 AH ++++ + +W +++ SL ++ R+WD F +G ++ + + Sbjct: 775 MAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEGTKYNEK----------E 824 Query: 629 ILTKMDFIHMAQFLTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREME 685 IL + + + Q+L + + +IA M K + L + ++ E E Sbjct: 825 ILRLQNGLEIYQYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAE 881 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,154,381 Number of Sequences: 37866 Number of extensions: 1280117 Number of successful extensions: 6479 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 89 Number of HSP's successfully gapped in prelim test: 137 Number of HSP's that attempted gapping in prelim test: 5830 Number of HSP's gapped (non-prelim): 700 length of query: 693 length of database: 18,247,518 effective HSP length: 109 effective length of query: 584 effective length of database: 14,120,124 effective search space: 8246152416 effective search space used: 8246152416 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.