Guide to the Human Genome
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Search of human proteins with 16445029

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens]
         (613 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens]      1237   0.0  
gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo...   288   1e-77
gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo...   281   2e-75
gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens]      279   5e-75
gi|41152506 prostaglandin F2 receptor negative regulator [Homo s...   228   1e-59
gi|169215606 PREDICTED: similar to immunoglobulin superfamily, m...   134   2e-31
gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens]    134   2e-31
gi|239753216 PREDICTED: similar to immunoglobulin superfamily, m...   124   3e-28
gi|144226847 obscurin-like 1 [Homo sapiens]                            44   6e-04
gi|239757668 PREDICTED: similar to Ig lambda chain [Homo sapiens]      44   6e-04
gi|169217835 PREDICTED: similar to hCG2038921 [Homo sapiens]           43   0.001
gi|169207803 PREDICTED: similar to hCG2038921 [Homo sapiens]           43   0.001
gi|13489095 sialoadhesin precursor [Homo sapiens]                      42   0.002
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             41   0.003
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact...    41   0.003
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    41   0.003
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi...    41   0.003
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap...    41   0.003
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap...    41   0.003
gi|239750758 PREDICTED: hypothetical protein XP_002347493 [Homo ...    40   0.005
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]         40   0.008
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    40   0.008
gi|67188443 CD276 antigen isoform a [Homo sapiens]                     39   0.011
gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]     39   0.018
gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]     39   0.018
gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]      39   0.018
gi|46094014 peptide chain release factor 3 [Homo sapiens]              39   0.018
gi|189571583 intercellular adhesion molecule 5 precursor [Homo s...    37   0.053
gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ...    37   0.053
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    37   0.070

>gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens]
          Length = 613

 Score = 1237 bits (3200), Expect = 0.0
 Identities = 613/613 (100%), Positives = 613/613 (100%)

Query: 1   MGALRPTLLPPSLPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQ 60
           MGALRPTLLPPSLPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQ
Sbjct: 1   MGALRPTLLPPSLPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQ 60

Query: 61  NFEWFLYRPEAPDTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQ 120
           NFEWFLYRPEAPDTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQ
Sbjct: 61  NFEWFLYRPEAPDTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQ 120

Query: 121 DAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQ 180
           DAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQ
Sbjct: 121 DAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQ 180

Query: 181 ELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAA 240
           ELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAA
Sbjct: 181 ELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAA 240

Query: 241 GELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQT 300
           GELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQT
Sbjct: 241 GELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQT 300

Query: 301 LSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVA 360
           LSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVA
Sbjct: 301 LSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVA 360

Query: 361 QLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLR 420
           QLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLR
Sbjct: 361 QLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLR 420

Query: 421 EAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWW 480
           EAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWW
Sbjct: 421 EAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWW 480

Query: 481 VERPEDGELSSVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEG 540
           VERPEDGELSSVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEG
Sbjct: 481 VERPEDGELSSVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEG 540

Query: 541 VYHCAPSAWVQHADYSWYQAGSARSGPVTVYPYMHALDTLFVPLLVGTGVALVTGATVLG 600
           VYHCAPSAWVQHADYSWYQAGSARSGPVTVYPYMHALDTLFVPLLVGTGVALVTGATVLG
Sbjct: 541 VYHCAPSAWVQHADYSWYQAGSARSGPVTVYPYMHALDTLFVPLLVGTGVALVTGATVLG 600

Query: 601 TITCCFMKRLRKR 613
           TITCCFMKRLRKR
Sbjct: 601 TITCCFMKRLRKR 613


>gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo
           sapiens]
          Length = 1194

 Score =  288 bits (736), Expect = 1e-77
 Identities = 186/564 (32%), Positives = 283/564 (50%), Gaps = 41/564 (7%)

Query: 15  LLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDT 74
           L  L +LG+    R+V V EGPLYR  G+ ++I CNV+GY+GP++QNF+W +Y P +P+ 
Sbjct: 8   LSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPER 67

Query: 75  ALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDT 134
            + IVST D+ F YA++  RV  G++ ++R+QG++ +L I  LQA+DAG YECHTPSTD 
Sbjct: 68  EVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDK 127

Query: 135 RYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVH--EGQELALGCLARTST 192
           +Y GSYS K+ L V+PD LQ +A P               T+H  E   L L C   + T
Sbjct: 128 QYFGSYSAKMNLVVIPDSLQTTAMP--------------QTLHRVEQDPLELTCEVASET 173

Query: 193 QKHTHLAVSFGR-SVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTD 251
            +H+HL+V++ R  V E PV      EV+ +  D  + + + YA+R + GE+RL K G  
Sbjct: 174 IQHSHLSVAWLRQKVGEKPV------EVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRT 227

Query: 252 RYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGP 311
            +R+ +   Q  D G ++C AAEWIQDPDGSW  +  KR+  A V+VQ    +  V +  
Sbjct: 228 TFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLET 287

Query: 312 GERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLG 371
            +R    GEP+E  C +     P  R+ A S  +  +     GP   V  L++E      
Sbjct: 288 EKRLHTVGEPVEFRCILEAQNVP-DRYFAVSWAFNSSLIATMGP-NAVPVLNSEFAHREA 345

Query: 372 PGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLP 431
            G     + + K +   + L++   R  D+G Y C      +       +  S R + +P
Sbjct: 346 RG----QLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIP 401

Query: 432 VHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSS 491
           + V      +          +  GE     C++   G P G R +  W +   ++   + 
Sbjct: 402 IIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQG-RFSVIWQLVDRQNRRSN- 459

Query: 492 VPAQLVGGVGQDGVAELG----VRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPS 547
                +  + +DG  + G     R   G V +E V P S  L + +   EDEG Y C  +
Sbjct: 460 -----IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVT 514

Query: 548 AWVQHADYSWYQAGSAR-SGPVTV 570
            WV+  D  W   G  R S P+++
Sbjct: 515 EWVRAVDGEWQIVGERRASTPISI 538



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 109/499 (21%), Positives = 188/499 (37%), Gaps = 58/499 (11%)

Query: 110  VVLKIARLQAQDAGIYEC-------HTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGP 162
            V L I+R    +AG Y+C       +  +T TR     S  +E+RVL  V ++       
Sbjct: 628  VRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKL------- 680

Query: 163  RGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGI 222
               Q   S   +T+ E + + L C  ++ T +++H AV +    P    G+  L+     
Sbjct: 681  ---QVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTT--- 734

Query: 223  RSDLAVEAGAPYAERLAAGELRLGKEGTDR-YRMVVGGAQAGDAGTYHCTAAEWIQDPDG 281
              + A E G    E      L+  +  +   + + V  A+  D+G+Y+C   EW+  P+ 
Sbjct: 735  -HNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNY 793

Query: 282  SWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAY 341
            +W ++AE+ +    V V+   S+L ++   G   +     ++L C V   L      +  
Sbjct: 794  AWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV---LNRTSITSQL 850

Query: 342  SVGWEMAPAGAPGPGRLVAQLDTEGVGSLGP-----GYEGRHIAMEKVASRTYRLRLEAA 396
             V W +     P     VA+L  +     G        +GR + +E  +   YRL ++  
Sbjct: 851  MVEWFVWKPNHP-ERETVARLSRDATFHYGEQAAKNNLKGR-LHLESPSPGVYRLFIQNV 908

Query: 397  RPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGE 456
               D+GTY C  + ++        + A   +    + V      L+    +   TV    
Sbjct: 909  AVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKA 968

Query: 457  TASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPA---------------------- 494
               L C+I  R      R A +W+  R + G   S P                       
Sbjct: 969  AFQLDCSIVSRSSQDS-RFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDP 1027

Query: 495  ---QLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQ 551
                 +  VG D V      P  G +  + + P  +RL +    P+D G Y C    W+ 
Sbjct: 1028 TERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLP 1087

Query: 552  HADYSWYQAGSARSGPVTV 570
                 WY+     S P+ +
Sbjct: 1088 SPQKEWYRLTEEESAPIGI 1106



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 89/441 (20%), Positives = 166/441 (37%), Gaps = 50/441 (11%)

Query: 40   VAGTAVSISCNVTGYEGPAQQNFE----WFLYRPEAPDTALGIVSTKDTQFSYAVF-KSR 94
            V    + ++C+V   +    QN      W++++P   D  L + +T ++ F Y  + +  
Sbjct: 692  VENKPIQLNCSV---KSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEE 748

Query: 95   VVAGEVQVQR-LQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVL 153
             +   +Q +R + G    L + R +  D+G Y CH    +     +Y+       +    
Sbjct: 749  GLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVE--EWLLSPNYAWYKLAEEVSGRT 806

Query: 154  QVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGR 213
            +V+   P  R R +      ++V E +++ L C+    T   + L V +    P  P   
Sbjct: 807  EVTVKQPDSRLRLSQAQG-NLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHP--- 862

Query: 214  STLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAA 273
               + V  +  D     G   A+    G L L       YR+ +      D+GTY C   
Sbjct: 863  -ERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVE 921

Query: 274  EWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALP 333
            EW+  P G W + AE  A    + V    + L V        +      +L C++   + 
Sbjct: 922  EWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSI---VS 978

Query: 334  PAGRHAAYSVGWEMAPAGAPG----PGRLVAQLDTE-----------------GVGSLGP 372
             + + + ++V W      A G    PG    + + E                  + S+GP
Sbjct: 979  RSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGP 1038

Query: 373  G---------YEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAA 423
                      +EGR +  ++++   YRL +  A P D G Y C  + ++           
Sbjct: 1039 DAVFGPEGSPWEGR-LRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLT 1097

Query: 424  SARSRPLPVHVREEGVVLEAV 444
               S P+ + V +    L+++
Sbjct: 1098 EEESAPIGIRVLDTSPTLQSI 1118



 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 97/485 (20%), Positives = 193/485 (39%), Gaps = 42/485 (8%)

Query: 98  GEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVEL---RVLPDVLQ 154
           G VQ++++Q ++  L I   + +D G YECH     T ++ +  G+ ++   R     + 
Sbjct: 482 GGVQMEQVQPNSFSLGIFNSRKEDEGQYECHV----TEWVRAVDGEWQIVGERRASTPIS 537

Query: 155 VSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRS 214
           ++A   G     A +  P +T  +  +L   C+ +        ++V++       PVG  
Sbjct: 538 ITALEMG-FAVTAISRTPGVTYSDSFDLQ--CIIKPHYPAWVPVSVTWRFQ----PVGTV 590

Query: 215 TLQEVVGIRSDLAVEAGAPYAERLAAGELRLG---KEGTDRYRMVVGGAQAGDAGTYHCT 271
              ++V    D     G  + +R ++   R      E ++  R+ +  A   +AG Y C 
Sbjct: 591 EFHDLVTFTRD----GGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCV 646

Query: 272 AAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGA 331
           A  W ++ + +W ++AE+ + L  + V    ++L V+       +   +P++L C+V   
Sbjct: 647 AELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKS- 705

Query: 332 LPPAGRHAAYSVGWEM-APAGAPGPGRLVAQLDTEGVGSLG-----PGYEGRHIAMEKVA 385
                +++ ++V W +  P+ A   G+L+ +         G      G   R      V+
Sbjct: 706 --QTSQNSHFAVLWYVHKPSDA--DGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVS 761

Query: 386 SRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVA 445
              + L ++ A   D+G+Y C  + ++        + A   S    V V++    L    
Sbjct: 762 GGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQ 821

Query: 446 WLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGV 505
                +V       L C +  R      +L   W+V +P   E      + V  + +D  
Sbjct: 822 AQGNLSVLETRQVQLECVVLNRTSITS-QLMVEWFVWKPNHPE-----RETVARLSRDAT 875

Query: 506 AELGVRPG----GGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAG 561
              G +       G + +E   P  +RL + ++  +D G Y C    W+      WY+  
Sbjct: 876 FHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRA 935

Query: 562 SARSG 566
              +G
Sbjct: 936 EDTAG 940


>gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo
           sapiens]
          Length = 1214

 Score =  281 bits (718), Expect = 2e-75
 Identities = 188/586 (32%), Positives = 287/586 (48%), Gaps = 65/586 (11%)

Query: 15  LLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDT 74
           L  L +LG+    R+V V EGPLYR  G+ ++I CNV+GY+GP++QNF+W +Y P +P+ 
Sbjct: 8   LSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPER 67

Query: 75  ALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDT 134
            + IVST D+ F YA++  RV  G++ ++R+QG++ +L I  LQA+DAG YECHTPSTD 
Sbjct: 68  EVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDK 127

Query: 135 RYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVH--EGQELALGCLARTST 192
           +Y GSYS K+ L V+PD LQ +A P               T+H  E   L L C   + T
Sbjct: 128 QYFGSYSAKMNLVVIPDSLQTTAMP--------------QTLHRVEQDPLELTCEVASET 173

Query: 193 QKHTHLAVSFGR-SVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTD 251
            +H+HL+V++ R  V E PV      EV+ +  D  + + + YA+R + GE+RL K G  
Sbjct: 174 IQHSHLSVAWLRQKVGEKPV------EVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRT 227

Query: 252 RYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGP 311
            +R+ +   Q  D G ++C AAEWIQDPDGSW  +  KR+  A V+VQ    +  V +  
Sbjct: 228 TFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLET 287

Query: 312 GERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLG 371
            +R    GEP+E  C +     P  R+ A S  +  +     GP   V  L++E      
Sbjct: 288 EKRLHTVGEPVEFRCILEAQNVP-DRYFAVSWAFNSSLIATMGP-NAVPVLNSEFAHREA 345

Query: 372 PGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLP 431
            G     + + K +   + L++   R  D+G Y C      +       +  S R + +P
Sbjct: 346 RG----QLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIP 401

Query: 432 VHV----------------------REEGVVLEAVAWLAGGTVYRGETASLLCNISVRGG 469
           + V                       E  + +E  +      +  GE     C++   G 
Sbjct: 402 IIVLPLTDNWVVKVPQHHQLLSQGHLESSISVEVAS--NASVILEGEDLRFSCSVRTAGR 459

Query: 470 PPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELG----VRPGGGPVSVELVGPR 525
           P G R +  W +   ++   +      +  + +DG  + G     R   G V +E V P 
Sbjct: 460 PQG-RFSVIWQLVDRQNRRSN------IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPN 512

Query: 526 SHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAGSAR-SGPVTV 570
           S  L + +   EDEG Y C  + WV+  D  W   G  R S P+++
Sbjct: 513 SFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISI 558



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 109/499 (21%), Positives = 188/499 (37%), Gaps = 58/499 (11%)

Query: 110  VVLKIARLQAQDAGIYEC-------HTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGP 162
            V L I+R    +AG Y+C       +  +T TR     S  +E+RVL  V ++       
Sbjct: 648  VRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKL------- 700

Query: 163  RGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGI 222
               Q   S   +T+ E + + L C  ++ T +++H AV +    P    G+  L+     
Sbjct: 701  ---QVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTT--- 754

Query: 223  RSDLAVEAGAPYAERLAAGELRLGKEGTDR-YRMVVGGAQAGDAGTYHCTAAEWIQDPDG 281
              + A E G    E      L+  +  +   + + V  A+  D+G+Y+C   EW+  P+ 
Sbjct: 755  -HNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNY 813

Query: 282  SWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAY 341
            +W ++AE+ +    V V+   S+L ++   G   +     ++L C V   L      +  
Sbjct: 814  AWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV---LNRTSITSQL 870

Query: 342  SVGWEMAPAGAPGPGRLVAQLDTEGVGSLGP-----GYEGRHIAMEKVASRTYRLRLEAA 396
             V W +     P     VA+L  +     G        +GR + +E  +   YRL ++  
Sbjct: 871  MVEWFVWKPNHP-ERETVARLSRDATFHYGEQAAKNNLKGR-LHLESPSPGVYRLFIQNV 928

Query: 397  RPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGE 456
               D+GTY C  + ++        + A   +    + V      L+    +   TV    
Sbjct: 929  AVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKA 988

Query: 457  TASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPA---------------------- 494
               L C+I  R      R A +W+  R + G   S P                       
Sbjct: 989  AFQLDCSIVSRSSQDS-RFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDP 1047

Query: 495  ---QLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQ 551
                 +  VG D V      P  G +  + + P  +RL +    P+D G Y C    W+ 
Sbjct: 1048 TERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLP 1107

Query: 552  HADYSWYQAGSARSGPVTV 570
                 WY+     S P+ +
Sbjct: 1108 SPQKEWYRLTEEESAPIGI 1126



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 89/441 (20%), Positives = 166/441 (37%), Gaps = 50/441 (11%)

Query: 40   VAGTAVSISCNVTGYEGPAQQNFE----WFLYRPEAPDTALGIVSTKDTQFSYAVF-KSR 94
            V    + ++C+V   +    QN      W++++P   D  L + +T ++ F Y  + +  
Sbjct: 712  VENKPIQLNCSV---KSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEE 768

Query: 95   VVAGEVQVQR-LQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVL 153
             +   +Q +R + G    L + R +  D+G Y CH    +     +Y+       +    
Sbjct: 769  GLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVE--EWLLSPNYAWYKLAEEVSGRT 826

Query: 154  QVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGR 213
            +V+   P  R R +      ++V E +++ L C+    T   + L V +    P  P   
Sbjct: 827  EVTVKQPDSRLRLSQAQG-NLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHP--- 882

Query: 214  STLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAA 273
               + V  +  D     G   A+    G L L       YR+ +      D+GTY C   
Sbjct: 883  -ERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVE 941

Query: 274  EWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALP 333
            EW+  P G W + AE  A    + V    + L V        +      +L C++   + 
Sbjct: 942  EWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSI---VS 998

Query: 334  PAGRHAAYSVGWEMAPAGAPG----PGRLVAQLDTE-----------------GVGSLGP 372
             + + + ++V W      A G    PG    + + E                  + S+GP
Sbjct: 999  RSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGP 1058

Query: 373  G---------YEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAA 423
                      +EGR +  ++++   YRL +  A P D G Y C  + ++           
Sbjct: 1059 DAVFGPEGSPWEGR-LRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLT 1117

Query: 424  SARSRPLPVHVREEGVVLEAV 444
               S P+ + V +    L+++
Sbjct: 1118 EEESAPIGIRVLDTSPTLQSI 1138



 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 97/485 (20%), Positives = 193/485 (39%), Gaps = 42/485 (8%)

Query: 98  GEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVEL---RVLPDVLQ 154
           G VQ++++Q ++  L I   + +D G YECH     T ++ +  G+ ++   R     + 
Sbjct: 502 GGVQMEQVQPNSFSLGIFNSRKEDEGQYECHV----TEWVRAVDGEWQIVGERRASTPIS 557

Query: 155 VSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRS 214
           ++A   G     A +  P +T  +  +L   C+ +        ++V++       PVG  
Sbjct: 558 ITALEMG-FAVTAISRTPGVTYSDSFDLQ--CIIKPHYPAWVPVSVTWRFQ----PVGTV 610

Query: 215 TLQEVVGIRSDLAVEAGAPYAERLAAGELRLG---KEGTDRYRMVVGGAQAGDAGTYHCT 271
              ++V    D     G  + +R ++   R      E ++  R+ +  A   +AG Y C 
Sbjct: 611 EFHDLVTFTRD----GGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCV 666

Query: 272 AAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGA 331
           A  W ++ + +W ++AE+ + L  + V    ++L V+       +   +P++L C+V   
Sbjct: 667 AELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKS- 725

Query: 332 LPPAGRHAAYSVGWEM-APAGAPGPGRLVAQLDTEGVGSLG-----PGYEGRHIAMEKVA 385
                +++ ++V W +  P+ A   G+L+ +         G      G   R      V+
Sbjct: 726 --QTSQNSHFAVLWYVHKPSDA--DGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVS 781

Query: 386 SRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVA 445
              + L ++ A   D+G+Y C  + ++        + A   S    V V++    L    
Sbjct: 782 GGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQ 841

Query: 446 WLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGV 505
                +V       L C +  R      +L   W+V +P   E      + V  + +D  
Sbjct: 842 AQGNLSVLETRQVQLECVVLNRTSITS-QLMVEWFVWKPNHPE-----RETVARLSRDAT 895

Query: 506 AELGVRPG----GGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAG 561
              G +       G + +E   P  +RL + ++  +D G Y C    W+      WY+  
Sbjct: 896 FHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRA 955

Query: 562 SARSG 566
              +G
Sbjct: 956 EDTAG 960


>gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens]
          Length = 1021

 Score =  279 bits (714), Expect = 5e-75
 Identities = 192/560 (34%), Positives = 278/560 (49%), Gaps = 59/560 (10%)

Query: 16  LLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDTA 75
           LLL  L +G   REV V +GPL+R  G  VSI CNVTG++GP++Q+F+W +Y P  P   
Sbjct: 12  LLLTKLSIG--QREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQE 69

Query: 76  LGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTR 135
           + I+STKD  FSYAV+  RV +G+V V+R+QG++V+L I++LQ +DAG YECHTP+TD +
Sbjct: 70  VQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEK 129

Query: 136 YLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKH 195
           Y GSYS K  L V+PD L             A  S   +   EG+ LAL C A  +T +H
Sbjct: 130 YYGSYSAKTNLIVIPDTL------------SATMSSQTLGKEEGEPLALTCEASKATAQH 177

Query: 196 THLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRM 255
           THL+V++  +      G S   E++ +  D  +  G  Y ER AA +++L K G   +R+
Sbjct: 178 THLSVTWYLT---QDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRL 234

Query: 256 VVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERR 315
            +   Q+ D G   C A EWIQDPD +W  I +K+     + +Q       V +   +  
Sbjct: 235 SIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNI-TADSL 293

Query: 316 IGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYE 375
              G+PLEL+C V      +GR       W          G  +A +D  GV  L   Y+
Sbjct: 294 FAEGKPLELVCLVVS----SGRDPQLQGIWFF-------NGTEIAHIDAGGVLGLKNDYK 342

Query: 376 GR----HIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVR---GSGTRLREAASARSR 428
            R     + + K+  + + L++ +  P D G YRC+    ++   GS   L+   S  S 
Sbjct: 343 ERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSH 402

Query: 429 PLPVHVRE---EGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPE 485
              VH+R+     VV+          V+ GET + LC       P    L+ SWW   P 
Sbjct: 403 ---VHLRKPAARSVVMSTKN--KQQVVWEGETLAFLCKAGGAESP----LSVSWW-HIPR 452

Query: 486 DGELSSVPAQLVGGVGQDGVAELGVRPG----GGPVSVELVGPRSHRLRLHSLGPEDEGV 541
           D        + V G+GQDG+ +LG   G     G   +E +   + +L +      D G 
Sbjct: 453 D----QTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGT 508

Query: 542 YHCAPS--AWVQHADYSWYQ 559
           Y C  S  +  Q  D SW Q
Sbjct: 509 YECRVSEKSRNQARDLSWTQ 528



 Score = 89.4 bits (220), Expect = 9e-18
 Identities = 130/535 (24%), Positives = 207/535 (38%), Gaps = 41/535 (7%)

Query: 42  GTAVSISCNVTGYEGPAQQNFEWFLYRPE-APDTALGIVSTKDTQFSYAVFKSRVVAGEV 100
           G  + + C V       Q    WF    E A   A G++  K+       +K R   GE+
Sbjct: 297 GKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKND------YKERASQGEL 350

Query: 101 QVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPP 160
           QV +L   A  LKI  L  +D G Y C          GS+   ++ +  PD   V    P
Sbjct: 351 QVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQ-VLQRKQSPDS-HVHLRKP 408

Query: 161 GPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVV 220
             R     T   +  V EG+ LA  C A  +    + L+VS+       P  ++  + V 
Sbjct: 409 AARSVVMSTKNKQQVVWEGETLAFLCKAGGA---ESPLSVSWWH----IPRDQTQPEFVA 461

Query: 221 GIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDP- 279
           G+  D  V+ GA Y      G  RL K     +++ +      D+GTY C  +E  ++  
Sbjct: 462 GMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQA 521

Query: 280 -DGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRH 338
            D SW Q          V V++L S L V++   + ++      +L C V      +   
Sbjct: 522 RDLSWTQKIS-------VTVKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGY--SDLK 572

Query: 339 AAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRL--EAA 396
              +V W+  PA +    +L+ ++   G    G  +  R     KV+   +R +L    A
Sbjct: 573 VPLTVTWQFQPASSHIFHQLI-RITHNGTIEWG-NFLSRFQKKTKVSQSLFRSQLLVHDA 630

Query: 397 RPGDAGTYRCLAKAYVRGSGTRLREA-ASARSRPLPVHVREEGVVLEAVAWLAGGTVYRG 455
              + G Y+C  + Y R S    R   ASA S PL + V      L+  +      +   
Sbjct: 631 TEEETGVYQCEVEVYDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQVQELSIN 690

Query: 456 ETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELG----VR 511
               + C+I  R     L+LA  W+   P     S +    +  + Q  V + G      
Sbjct: 691 SNTDIECSILSRSNG-NLQLAIIWYFS-PVSTNASWLK---ILEMDQTNVIKTGDEFHTP 745

Query: 512 PGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAGSARSG 566
                   E V     +L + ++   D G YHCA   W+   + +W++ G  +SG
Sbjct: 746 QRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSG 800



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 42/189 (22%), Positives = 83/189 (43%), Gaps = 6/189 (3%)

Query: 247 KEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLA 306
           K   D +++ +   +  D G YHC   EW+   +G+W ++ EK++ L  + ++   S++ 
Sbjct: 755 KVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVR 814

Query: 307 VTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEG 366
           V+       +     + + C++      A     YSV W      +    +L+  L  +G
Sbjct: 815 VSKVYWTENVTEHREVAIRCSLESVGSSA---TLYSVMWYWNRENS--GSKLLVHLQHDG 869

Query: 367 VGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRC-LAKAYVRGSGTRLREAASA 425
           +   G     RH+   + +S  + L+L      DAG Y C +A+  + G  ++    AS 
Sbjct: 870 LLEYGEEGLRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASD 929

Query: 426 RSRPLPVHV 434
            S+ + + V
Sbjct: 930 ESQRMVLTV 938



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 97/539 (17%), Positives = 191/539 (35%), Gaps = 49/539 (9%)

Query: 42  GTAVSISCNVTGYEGPAQQNFEWFLYRPEA-PDTALGIVSTKDTQFSYAVFKSRVVAGEV 100
           G  ++  C   G E P   ++ W + R +  P+   G+      Q   A +      G  
Sbjct: 427 GETLAFLCKAGGAESPLSVSW-WHIPRDQTQPEFVAGMGQDGIVQLG-ASYGVPSYHGNT 484

Query: 101 QVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLG--SYSGKVELRV--LPDVLQVS 156
           +++++      L+I      D+G YEC             S++ K+ + V  L   LQVS
Sbjct: 485 RLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLESSLQVS 544

Query: 157 AAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTL 216
                P+     T              L C+ R     ++ L V    +    P      
Sbjct: 545 LMSRQPQVMLTNT------------FDLSCVVRAG---YSDLKVPLTVTWQFQPASSHIF 589

Query: 217 QEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWI 276
            +++ I  +  +E G   +      ++    +   R +++V  A   + G Y C     +
Sbjct: 590 HQLIRITHNGTIEWGNFLSRFQKKTKV---SQSLFRSQLLVHDATEEETGVYQCEVE--V 644

Query: 277 QDPDGSWAQIAEKRAVLAH---VDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALP 333
            D +  +     + + ++H   + V    S+L V      + +      ++ C++   L 
Sbjct: 645 YDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSI---LS 701

Query: 334 PAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEG----RHIAMEKVASRTY 389
            +  +   ++ W  +P         + ++D   V   G  +      +    EKV+   +
Sbjct: 702 RSNGNLQLAIIWYFSPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQDLF 761

Query: 390 RLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEG--VVLEAVAWL 447
           +L +      D G Y C  + ++  +     +    +S    + ++  G  V +  V W 
Sbjct: 762 QLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWT 821

Query: 448 AGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAE 507
              T +R    ++ C++   G    L  +  W+  R   G      ++L+  +  DG+ E
Sbjct: 822 ENVTEHR--EVAIRCSLESVGSSATL-YSVMWYWNRENSG------SKLLVHLQHDGLLE 872

Query: 508 LGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYS-WYQAGSARS 565
            G       +           L+LH +  ED G+Y C  + W  H   S W    S  S
Sbjct: 873 YGEEGLRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASDES 931


>gi|41152506 prostaglandin F2 receptor negative regulator [Homo
           sapiens]
          Length = 879

 Score =  228 bits (581), Expect = 1e-59
 Identities = 163/565 (28%), Positives = 260/565 (46%), Gaps = 33/565 (5%)

Query: 12  SLPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEA 71
           S PLLL L+    C  R V VP   L RV GT + I CNV+ Y+GP++QNF+W       
Sbjct: 6   SRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF--SSL 63

Query: 72  PDTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPS 131
             + + + ST +  F   +++ R+  GE+ ++R   DAV L I  +Q  D G Y+C TPS
Sbjct: 64  GSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPS 123

Query: 132 TDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTS 191
           TD    G+Y   V+++VL D L V     GP  R     PP +++ EG+   L C A ++
Sbjct: 124 TDATVQGNYEDTVQVKVLADSLHV-----GPSAR----PPPSLSLREGEPFELRCTAASA 174

Query: 192 TQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTD 251
           +  HTHLA+ +   V   P  RS    V+ +  +     G  Y +R  +G++RL   G+D
Sbjct: 175 SPLHTHLALLW--EVHRGPARRS----VLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSD 228

Query: 252 RYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGP 311
            YR+ V  A + D G+Y C  +EWI +  G+W +I EK   +A V +Q    + AV   P
Sbjct: 229 AYRLSVSRALSADQGSYRCIVSEWIAE-QGNWQEIQEKAVEVATVVIQPSVLRAAV---P 284

Query: 312 GERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLG 371
               +  G+ L+L CN++       R         M  +  PG  R++A+LD + +    
Sbjct: 285 KNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPG-SRVLARLDRDSLVHSS 343

Query: 372 PGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLP 431
           P     H+A+  V +R+Y L +      ++G Y C    +  G      + A A S P  
Sbjct: 344 P-----HVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAG 398

Query: 432 VHVREEGVVLEAVAWLAGGTVYRGETASLLCN-ISVRGGPPGLRLAASWWVERPEDGELS 490
           V V       +     +    +  +   L C  +  + G   +R   SW+       + +
Sbjct: 399 VGVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSD-N 457

Query: 491 SVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSH----RLRLHSLGPEDEGVYHCAP 546
            V ++L+  +  D   + G R        + +  + H      R+     ED G Y+C  
Sbjct: 458 VVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVV 517

Query: 547 SAWVQHADYSWYQAGSARSGPVTVY 571
           SAW +  + SW ++    S PV ++
Sbjct: 518 SAWTKQRNNSWVKSKDVFSKPVNIF 542



 Score =  129 bits (325), Expect = 6e-30
 Identities = 110/500 (22%), Positives = 201/500 (40%), Gaps = 16/500 (3%)

Query: 112 LKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSP 171
           L +  +  +++G Y CH       +  S+    E    P  + V+   P  +     +  
Sbjct: 358 LLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKV 417

Query: 172 PRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAG 231
           P     +  ELA   +   S + +    VS+   +        T + +  +  D  ++ G
Sbjct: 418 PGFA-DDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYG 476

Query: 232 APYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRA 291
               +R   G+    KE TD +   +      D G Y+C  + W +  + SW +  +  +
Sbjct: 477 ERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFS 536

Query: 292 VLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWE-MAPA 350
              ++      S L V     +     G   E+ C VS     + R++   +  + +   
Sbjct: 537 KPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDL 596

Query: 351 GAPGPGRLVAQLDTEGVGSLGPGYEGRHI---AMEKVASRTYRLRLEAARPGDAGTYRCL 407
            +P   + +  LD + V  L    +   +    +EKV    +R R+   +  DAG YRC+
Sbjct: 597 SSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCM 656

Query: 408 AKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVR 467
             A+    G+  REAA++ S P+ +  +  G +  A       +V RG+   L C I+V 
Sbjct: 657 VTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVE 716

Query: 468 GG---PPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGP 524
           G    P  +    SW+       + + V   L+  + + G+     R     +S+E V  
Sbjct: 717 GAALDPDDMAFDVSWFAVHSFGLDKAPV---LLSSLDRKGIVTTSRRDWKSDLSLERVSV 773

Query: 525 RSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAGSARSGPVTVYPYMHALDTLFVPL 584
               L++H    +D G Y+C+ + WV+    SW +     S PV +   M  L+    PL
Sbjct: 774 LEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITVKMDVLNAFKYPL 833

Query: 585 LVGTGVALVTGATVLGTITC 604
           L+G G+     +TV+G ++C
Sbjct: 834 LIGVGL-----STVIGLLSC 848


>gi|169215606 PREDICTED: similar to immunoglobulin superfamily,
           member 3 [Homo sapiens]
          Length = 195

 Score =  134 bits (337), Expect = 2e-31
 Identities = 58/112 (51%), Positives = 84/112 (75%)

Query: 28  REVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDTALGIVSTKDTQFS 87
           R+V V EGPLYR  G+ ++I CNV+GY+GP++QNF+W +Y P +P+  + IVST D+ F 
Sbjct: 84  RQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTMDSSFP 143

Query: 88  YAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGS 139
           YA++  RV  G++ ++R+QG+  +L I  LQA+DAG YECHTPST+ +Y GS
Sbjct: 144 YAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECHTPSTEKQYFGS 195



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 13/140 (9%)

Query: 268 YHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCN 327
           +H    E+++  DG         A L   +   +S+Q  VTV  G      G  + + CN
Sbjct: 56  WHLFHHEFLRQSDG---------ATLFQNNHSVVSAQRQVTVQEGPLYRTEGSHITIWCN 106

Query: 328 VSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSL-GPGYEGRHIAMEKVAS 386
           VSG   P+ ++  +S+     P+      ++V+ +D+    ++      G  I +E+V  
Sbjct: 107 VSGYQGPSEQNFQWSI---YLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQG 163

Query: 387 RTYRLRLEAARPGDAGTYRC 406
               L +   +  DAG Y C
Sbjct: 164 NPTLLHITDLQARDAGEYEC 183


>gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens]
          Length = 155

 Score =  134 bits (337), Expect = 2e-31
 Identities = 58/112 (51%), Positives = 84/112 (75%)

Query: 28  REVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDTALGIVSTKDTQFS 87
           R+V V EGPLYR  G+ ++I CNV+GY+GP++QNF+W +Y P +P+  + IVST D+ F 
Sbjct: 44  RQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTMDSSFP 103

Query: 88  YAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGS 139
           YA++  RV  G++ ++R+QG+  +L I  LQA+DAG YECHTPST+ +Y GS
Sbjct: 104 YAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECHTPSTEKQYFGS 155



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 13/140 (9%)

Query: 268 YHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCN 327
           +H    E+++  DG         A L   +   +S+Q  VTV  G      G  + + CN
Sbjct: 16  WHLFHHEFLRQSDG---------ATLVQNNHSVVSAQRQVTVQEGPLYRTEGSHITIWCN 66

Query: 328 VSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSL-GPGYEGRHIAMEKVAS 386
           VSG   P+ ++  +S+     P+      ++V+ +D+    ++      G  I +E+V  
Sbjct: 67  VSGYQGPSEQNFQWSI---YLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQG 123

Query: 387 RTYRLRLEAARPGDAGTYRC 406
               L +   +  DAG Y C
Sbjct: 124 NPTLLHITDLQARDAGEYEC 143


>gi|239753216 PREDICTED: similar to immunoglobulin superfamily,
           member 3 [Homo sapiens]
          Length = 376

 Score =  124 bits (310), Expect = 3e-28
 Identities = 97/360 (26%), Positives = 158/360 (43%), Gaps = 22/360 (6%)

Query: 218 EVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQ 277
           EV+ +  D  + +G+ YA R + GE+RL K G   +R+ +   Q  D G ++C AAEWIQ
Sbjct: 27  EVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQ 86

Query: 278 DPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGR 337
           +PDGSW  +  KR+  A V+VQ    +  V +   +R    GEP+E  C +  A     R
Sbjct: 87  NPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRC-IPEAQNVPDR 145

Query: 338 HAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAAR 397
           + A S  +  +     GP   V  L++E       G     + + K +   + L++   R
Sbjct: 146 YFAVSWAFNSSLIATMGP-NAVPVLNSEFAHREARG----QLNVAKESDSVFVLKIYHLR 200

Query: 398 PGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHV--REEGVVLEAVAWLAGGTVYRG 455
             D+G Y C      +       +  S   + +P+ V   E  + +E  +      +  G
Sbjct: 201 QEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVAS--NASVILEG 258

Query: 456 ETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELG----VR 511
           E     C++ + G P G R +  W +   ++          +  + +DG  + G     R
Sbjct: 259 EDLRFSCSVRMAGRPQG-RFSVIWQLVDRQNRRSD------IMWLDRDGTVQPGSSYWER 311

Query: 512 PGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAGSAR-SGPVTV 570
              G V +E V P S  L + +   EDEG Y C  + WV+  D  W   G  R S P+++
Sbjct: 312 SSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISI 371



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 44/208 (21%), Positives = 87/208 (41%), Gaps = 22/208 (10%)

Query: 91  FKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGK------- 143
           F  R   G++ V +      VLKI  L+ +D+G Y C     +    G +  K       
Sbjct: 173 FAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKN 232

Query: 144 VELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFG 203
           + + VLP    +S             +     + EG++L   C  R + +     +V   
Sbjct: 233 IPIIVLPLESSIS----------VEVASNASVILEGEDLRFSCSVRMAGRPQGRFSV--- 279

Query: 204 RSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAG 263
             + +    ++   +++ +  D  V+ G+ Y ER + G +++ +   + + + +  ++  
Sbjct: 280 --IWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKE 337

Query: 264 DAGTYHCTAAEWIQDPDGSWAQIAEKRA 291
           D G Y C   EW++  DG W  + E+RA
Sbjct: 338 DEGQYECHVTEWVRVVDGEWQIVGERRA 365



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 74/320 (23%), Positives = 119/320 (37%), Gaps = 22/320 (6%)

Query: 98  GEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSA 157
           GEV++ +L      L I  LQ  D G + C          GS+      R    V+ V  
Sbjct: 50  GEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQ- 108

Query: 158 APPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQ 217
             P  +         +     G+ +   C+         + AVS+  +        S+L 
Sbjct: 109 --PTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFN--------SSLI 158

Query: 218 EVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQ 277
             +G   +      + +A R A G+L + KE    + + +   +  D+G Y+C   E  +
Sbjct: 159 ATMG--PNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREK 216

Query: 278 DPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGR 337
              G +     K      + V  L S ++V V      I  GE L   C+V  A  P GR
Sbjct: 217 TVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGR 276

Query: 338 HAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGR----HIAMEKVASRTYRLRL 393
              +SV W++           +  LD +G    G  Y  R     + ME+V   ++ L +
Sbjct: 277 ---FSVIWQL--VDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGI 331

Query: 394 EAARPGDAGTYRCLAKAYVR 413
             +R  D G Y C    +VR
Sbjct: 332 FNSRKEDEGQYECHVTEWVR 351


>gi|144226847 obscurin-like 1 [Homo sapiens]
          Length = 1896

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 101/415 (24%), Positives = 145/415 (34%), Gaps = 103/415 (24%)

Query: 95   VVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDV-- 152
            V   E  V    G    L +   Q +D G + C        +  + +   E  V P    
Sbjct: 1029 VEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARS 1088

Query: 153  LQVSAAPPG---------PRGRQAPTSPPRMTVHEGQELALGCLA--RTSTQKHT----- 196
            L +    PG         P G Q       + V     L LG     RT T  H      
Sbjct: 1089 LDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDA 1148

Query: 197  --------HLAVSFGRSVPEAPVGRSTLQ-----------EVVGIRSDLAVEAGAPYA-- 235
                    H A++F   + E PV    L+           E V +  +L+  AGAP    
Sbjct: 1149 GEYVCETRHEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELS-RAGAPVVWS 1207

Query: 236  ---ERLAAGE-LRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWA-QIAEKR 290
                 +  GE L L  EG  R  + +  A    AG Y C +      P  S+  Q+AE  
Sbjct: 1208 HNGRPVQEGEGLELHAEGPRRV-LCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEP- 1265

Query: 291  AVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPA 350
                   V+ ++ + A T      R  PG  LEL+ ++SG   P G    Y  G  +A  
Sbjct: 1266 ------PVRVVAPEAAQT----RVRSTPGGDLELVVHLSG---PGGPVRWYKDGERLASQ 1312

Query: 351  GAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKA 410
            G                           + +E+  +R   LR++ AR GDAG Y C    
Sbjct: 1313 G--------------------------RVQLEQAGARQV-LRVQGARSGDAGEYLC---- 1341

Query: 411  YVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNIS 465
                        A   SR   V V EE ++++ V+ L   TV+ G+ A+  C +S
Sbjct: 1342 -----------DAPQDSRIFLVSV-EEPLLVKLVSELTPLTVHEGDDATFRCEVS 1384



 Score = 37.4 bits (85), Expect = 0.041
 Identities = 80/336 (23%), Positives = 115/336 (34%), Gaps = 91/336 (27%)

Query: 252  RYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGP 311
            R+R+V+ G    D+G    TA           +     R ++  V V        +  GP
Sbjct: 1593 RHRLVLNGLGLADSGCVSFTAD----------SLRCAARLIVREVPV-------TIVRGP 1635

Query: 312  GERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEM-APAGAPGPGRLVAQLDTEGVGSL 370
             +  +  G+     C +S AL          V WE    A  P P   +  L T  +  L
Sbjct: 1636 HDLEVTEGDTATFECELSQALA--------DVTWEKDGNALTPSPRLRLQALGTRRLLQL 1687

Query: 371  ---GPGYEG--------------RHIAMEKVASRTYRLRLEAARPGDAGTYRC-LAKAYV 412
               GP   G              R    E+  +    LR  +AR GD  T+ C +++   
Sbjct: 1688 RRCGPSDAGTYSCAVGTARAGPVRLTVRERTVAVLSELRSVSAREGDGATFECTVSEVET 1747

Query: 413  RG----SGTRLREAASARSRPLPVHVREEG-----VVLEAVAWLAGGTVYRGETASLLCN 463
             G     G  LR  A  R       +R+EG     V+ E  A  AG   ++   A  L  
Sbjct: 1748 TGRWELGGRPLRPGARVR-------IRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLAL 1800

Query: 464  ISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELGVRPGGGPV-----S 518
            + V   P  +                   P +    VG+  V E+ V   GG V      
Sbjct: 1801 LEVEALPLQM---------------CRHPPREKTVLVGRRAVLEVTVSRSGGHVCWLREG 1845

Query: 519  VELV----------GPRSHRLRLHSLGPEDEGVYHC 544
             EL           GP +H L +H + PED+G Y C
Sbjct: 1846 AELCPGDKYEMRSHGP-THSLVIHDVRPEDQGTYCC 1880



 Score = 29.6 bits (65), Expect = 8.5
 Identities = 38/170 (22%), Positives = 62/170 (36%), Gaps = 54/170 (31%)

Query: 98   GEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSA 157
            G VQ+++  G   VL++   ++ DAG Y C  P     +L S    + ++++ ++     
Sbjct: 1313 GRVQLEQA-GARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLVSELTP--- 1368

Query: 158  APPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQ 217
                            +TVHEG +    C                  S P+A        
Sbjct: 1369 ----------------LTVHEGDDATFRCEV----------------SPPDA-------- 1388

Query: 218  EVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGT 267
            +V  +R+   V  G P  E    G  R+         + + G Q GDAGT
Sbjct: 1389 DVTWLRNGAVVTPG-PQVEMAQNGSSRI---------LTLRGCQLGDAGT 1428


>gi|239757668 PREDICTED: similar to Ig lambda chain [Homo sapiens]
          Length = 288

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 37/141 (26%), Positives = 57/141 (40%), Gaps = 13/141 (9%)

Query: 12  SLPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRP-E 70
           +L  L LL  G G WA+  L     +    G +++ISC  T  +        W+   P +
Sbjct: 4   ALLFLTLLTQGTGSWAQSALTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQHPGK 63

Query: 71  APDTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHT- 129
           AP   +  VS + +  S     S+            G+   L I+ LQA+D   Y C + 
Sbjct: 64  APKLMIYDVSNRPSGVSNRFSGSK-----------SGNTASLTISGLQAEDEADYYCSSY 112

Query: 130 PSTDTRYLGSYSGKVELRVLP 150
            S+ T + G  S   E +  P
Sbjct: 113 TSSSTLHSGPSSWGTETKTCP 133


>gi|169217835 PREDICTED: similar to hCG2038921 [Homo sapiens]
          Length = 120

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 6/116 (5%)

Query: 15  LLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDT 74
           +LLL+    G  A   LV  G   +  G  V ISC V+GY         W    P     
Sbjct: 7   ILLLVAAATGTHAEVQLVQSGAEVKKPGATVKISCKVSGYTF-TDYYMHWVQQAPGKGLE 65

Query: 75  ALGIVSTKDTQFSYA-VFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHT 129
            +G+V  +D +  YA  F+ RV            D   ++++ L+++D  +Y C T
Sbjct: 66  WMGLVDPEDGETIYAEKFQGRVTI----TADTSTDTAYMELSSLRSEDTAVYYCAT 117


>gi|169207803 PREDICTED: similar to hCG2038921 [Homo sapiens]
          Length = 120

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 6/116 (5%)

Query: 15  LLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDT 74
           +LLL+    G  A   LV  G   +  G  V ISC V+GY         W    P     
Sbjct: 7   ILLLVAAATGTHAEVQLVQSGAEVKKPGATVKISCKVSGYTF-TDYYMHWVQQAPGKGLE 65

Query: 75  ALGIVSTKDTQFSYA-VFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHT 129
            +G+V  +D +  YA  F+ RV            D   ++++ L+++D  +Y C T
Sbjct: 66  WMGLVDPEDGETIYAEKFQGRVTI----TADTSTDTAYMELSSLRSEDTAVYYCAT 117


>gi|13489095 sialoadhesin precursor [Homo sapiens]
          Length = 1709

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 93/394 (23%), Positives = 132/394 (33%), Gaps = 119/394 (30%)

Query: 207 PEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQ----- 261
           P  P   S ++ + G   D       PY       ++RL  +G D  R V   +Q     
Sbjct: 139 PRVPTIASPVELLEGTEVDF--NCSTPYV--CLQEQVRLQWQGQDPARSVTFNSQKFEPT 194

Query: 262 -AGDAGTYHCTAAEWIQDPDG---SWAQIAEKRAVLA-HVDVQTLSSQLAVTVGPGERRI 316
             G   T H  A  W QD          +A  RA    H+ V+     + + + P  R I
Sbjct: 195 GVGHLETLHM-AMSW-QDHGRILRCQLSVANHRAQSEIHLQVKYAPKGVKILLSPSGRNI 252

Query: 317 GPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEG 376
            PGE + L C V+ + P     A  S+ W                   +GV         
Sbjct: 253 LPGELVTLTCQVNSSYP-----AVSSIKWLK-----------------DGV--------- 281

Query: 377 RHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVRE 436
                 ++ ++T  L L  A   DAG Y C A+  V           S  S P+ +H+  
Sbjct: 282 ------RLQTKTGVLHLPQAAWSDAGVYTCQAENGV----------GSLVSPPISLHI-- 323

Query: 437 EGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQL 496
               +  V     G +   +T +L+CN +    P  LR   SW+                
Sbjct: 324 ---FMAEVQVSPAGPILENQTVTLVCN-TPNEAPSDLRY--SWYKNH------------- 364

Query: 497 VGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYS 556
                                 V L    SH LRLH     D G Y C     VQ+    
Sbjct: 365 ----------------------VLLEDAHSHTLRLHLATRADTGFYFCE----VQNVH-- 396

Query: 557 WYQAGSARSGPVTV---YPYMHALDTLFVPLLVG 587
               GS RSGPV+V   +P +  + T F+    G
Sbjct: 397 ----GSERSGPVSVVVNHPPLTPVLTAFLETQAG 426



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 111/505 (21%), Positives = 170/505 (33%), Gaps = 121/505 (23%)

Query: 104  RLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPR 163
            + + +++ L++  L   D+G Y C      T  LGS +  +  +V    +QVS +P    
Sbjct: 853  KAEANSLKLEVRELGLGDSGSYRCEA----TNVLGSSNTSLFFQVRGAWVQVSPSPELQE 908

Query: 164  GR------QAPTSPPRMTVH----EGQEL-------------------ALGCLARTSTQK 194
            G+      Q  T  P  T +    +GQ L                   A  C A+     
Sbjct: 909  GQAVVLSCQVHTGVPEGTSYRWYRDGQPLQESTSATLRFAAITLTQAGAYHCQAQAPGSA 968

Query: 195  HTHLAVSFGRSVPEAP--VGRSTLQE---------VVGIRSDLAVEAGAPYAERLAAGEL 243
             T LA      V  AP  V  +TL +         +  + SD   +    + +RL A  L
Sbjct: 969  TTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLVASTL 1028

Query: 244  RL--GKEGT----------DRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGS--------- 282
            +   G EG+          +  R+ + GA   D G Y C A+  +     S         
Sbjct: 1029 QGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLEDEGVYICEASNTLGQASASADFDAQAVN 1088

Query: 283  ---WAQIAEKRAVLAHVDV---QTLSSQLAVT-VGPGERRIG------PGEPLELLCNVS 329
               W     +   L ++      T  +QL  T    G++R+       P   +    +  
Sbjct: 1089 VQVWPGATVREGQLVNLTCLVWTTHPAQLTYTWYQDGQQRLDAHSIPLPNVTVRDATSYR 1148

Query: 330  GALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEG--------------VGSLGPGYE 375
              + P GR    S    +    AP   RL   L++ G                 L   + 
Sbjct: 1149 CGVGPPGRAPRLSRPITLDVLYAPRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHA 1208

Query: 376  GRHIAMEKVAS--RTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLR------------E 421
            GR +A    AS   T RL L   +P D G Y C A++ +  + T L             E
Sbjct: 1209 GRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANTSLELRLEGVRVILAPE 1268

Query: 422  AASARSRPLPVHVREEGVVLEAV-AWLAGGT-VYRGETASLLCNISVRG----------- 468
            AA     P+ V   +       +  W   G  +  G  ASL   ++ R            
Sbjct: 1269 AAVPEGAPITVTCADPAAHAPTLYTWYHNGRWLQEGPAASLSFLVATRAHAGAYSCQAQD 1328

Query: 469  --GPPGLRLAASWWVERPEDGELSS 491
              G    R AA   +  P+D  LSS
Sbjct: 1329 AQGTRSSRPAALQVLYAPQDAVLSS 1353



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 64/250 (25%), Positives = 89/250 (35%), Gaps = 41/250 (16%)

Query: 314  RRIGPGEPLELLCNVSGALPPAGRHAAYSV--GW-EMAPAGAPGPGRLVA---QLDTEGV 367
            R +G G+     C  +  L  +     + V   W +++P+     G+ V    Q+ T GV
Sbjct: 864  RELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPELQEGQAVVLSCQVHT-GV 922

Query: 368  GSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARS 427
               G  Y           S +  LR  A     AG Y C A+A   GS T      ++ +
Sbjct: 923  PE-GTSYRWYRDGQPLQESTSATLRFAAITLTQAGAYHCQAQA--PGSAT------TSLA 973

Query: 428  RPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPG-LRLAASWWVERPED 486
             P+ +HV      +     +  G    G    LLC +     PP  LRL           
Sbjct: 974  APISLHVSYAPRHVTLTTLMDTGP---GRLGLLLCRVD--SDPPAQLRLL--------HG 1020

Query: 487  GELSSVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAP 546
              L +   Q VGG             G  P     V P + RL +H    EDEGVY C  
Sbjct: 1021 DRLVASTLQGVGGP-----------EGSSPRLHVAVAPNTLRLEIHGAMLEDEGVYICEA 1069

Query: 547  SAWVQHADYS 556
            S  +  A  S
Sbjct: 1070 SNTLGQASAS 1079


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 82/376 (21%), Positives = 120/376 (31%), Gaps = 126/376 (33%)

Query: 31   LVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDTALGIVSTKDTQFSYAV 90
            ++PEGP++   G AV++ C   G              R  A  T +     K  Q +Y +
Sbjct: 3116 VLPEGPVWVKVGKAVTLECVSAGEP------------RSSARWTRISSTPAKLEQRTYGL 3163

Query: 91   FKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLP 150
              S                 VL+I+  +  DAG Y C   +     LG+   +VE+    
Sbjct: 3164 MDSH---------------AVLQISSAKPSDAGTYVCLAQNA----LGTAQKQVEV---- 3200

Query: 151  DVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAP 210
             ++   A  PG    Q       +TV  G    L C A  S     H +           
Sbjct: 3201 -IVDTGAMAPG--APQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWS----------- 3246

Query: 211  VGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHC 270
                       +RS L      P+  RL    L            ++      D+G Y C
Sbjct: 3247 ----------KLRSPL------PWQHRLEGDTL------------IIPRVAQQDSGQYIC 3278

Query: 271  TAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSG 330
             A      P G       +  ++ HV+    S   A TV P    +  GE ++L C   G
Sbjct: 3279 NAT----SPAGH-----AEATIILHVE----SPPYATTV-PEHASVQAGETVQLQCLAHG 3324

Query: 331  ALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYR 390
              P         + ++ +  G+  PGR  A                          R   
Sbjct: 3325 TPP---------LTFQWSRVGSSLPGRATA--------------------------RNEL 3349

Query: 391  LRLEAARPGDAGTYRC 406
            L  E A P D+G YRC
Sbjct: 3350 LHFERAAPEDSGRYRC 3365



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 48/201 (23%), Positives = 75/201 (37%), Gaps = 37/201 (18%)

Query: 255  MVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGER 314
            + +   Q  DAGTY CT +       G+            HV      S   V++ P + 
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGT---------ATLHVQASGTLSAPVVSIHPPQL 1875

Query: 315  RIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGY 374
             + PG+  E  C+ +G+  P       ++ W     G PG G+L A+    G G L    
Sbjct: 1876 TVQPGQLAEFRCSATGSPTP-------TLEW----TGGPG-GQLPAKAQIHG-GIL---- 1918

Query: 375  EGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARS-----RP 429
              R  A+E      Y  R  ++    AG     A  +V G G    + +  R+     R 
Sbjct: 1919 --RLPAVEPTDQAQYLCRAHSS----AGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRT 1972

Query: 430  LPVHVREEGVVLEAVAWLAGG 450
            + ++ R  GV    + W   G
Sbjct: 1973 VRLYCRAAGVPSATITWRKEG 1993



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 48/183 (26%), Positives = 64/183 (34%), Gaps = 47/183 (25%)

Query: 265  AGTYHCTAAEWIQDPDGSWAQIAEK--RAVLAHVDVQ-------TLSSQLAVTVGPGERR 315
            AG Y CTA E      G   Q  E+     + +  VQ       T  + L V V P    
Sbjct: 1633 AGGYRCTACE-----PGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHPARSI 1687

Query: 316  IGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYE 375
            +  G    L C VSG+ P    H  Y   W     G P P                 G +
Sbjct: 1688 VPQGGSHSLRCQVSGSPP----HYFY---WSRED-GRPVPS----------------GTQ 1723

Query: 376  GRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLR-EAASARSRPLPVHV 434
             RH   E        L   + +P DAG Y C  +   + + +R       A S+P+ V V
Sbjct: 1724 QRHQGSE--------LHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTV 1775

Query: 435  REE 437
             E+
Sbjct: 1776 EEQ 1778



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 87/350 (24%), Positives = 117/350 (33%), Gaps = 67/350 (19%)

Query: 104  RLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPR 163
            R Q    +L++ ++   D+G Y CH   T        SG +E  VL  +       P P 
Sbjct: 2195 RHQTHGSLLRLHQVTPADSGEYVCHVVGT--------SGPLEASVLVTIEASVIPGPIPP 2246

Query: 164  GRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLA-VSFGRSVP--------------- 207
             R   +S    TV EGQ L L C+   + Q H  +     G S+P               
Sbjct: 2247 VRIESSS---STVAEGQTLDLSCV--VAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQA 2301

Query: 208  -EAPVGRSTLQEVVGIRSDLAVEAGAPYAERLA--AGELRLGKEGTDRYRMVVGGAQAGD 264
              A  G+   +   G+ + + V         LA  AG        T   R+    +Q  +
Sbjct: 2302 SPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAG-------STQPIRIEPSSSQVAE 2354

Query: 265  AGTYHCTAAEWIQDPDGSWAQIA-EKRAVLAHVDVQTLSSQL----AVTVGPGE---RRI 316
              T           P  S AQ+   KR     V  QT  S L    A     GE   R +
Sbjct: 2355 GQTLDLNCVV----PGQSHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVL 2410

Query: 317  GPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEG 376
            G   PLE   +V   + PAG   A  V               VA+  T  +  L  G   
Sbjct: 2411 GSSVPLE--ASVLVTIEPAGSVPALGV---TPTVRIESSSSQVAEGQTLDLNCLVAGQAH 2465

Query: 377  RHIAMEKVAS--------RTYRLRLEAARPGDAGTYRCLAKAYVRGSGTR 418
              +   K              RLRL    P D+G Y C     V  SGT+
Sbjct: 2466 AQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVC---RVVGSSGTQ 2512



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 31/99 (31%), Positives = 42/99 (42%), Gaps = 25/99 (25%)

Query: 383  KVASRTYRL-------RLEAARPGDAGTYRCLAKAYVRGSGTRLREAA----SARSRPLP 431
            K+  RTY L       ++ +A+P DAGTY CLA+      GT  ++      +    P  
Sbjct: 3155 KLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQ---NALGTAQKQVEVIVDTGAMAPGA 3211

Query: 432  VHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGP 470
              V+ E   L         TV  G TA+L C  S  G P
Sbjct: 3212 PQVQAEEAEL---------TVEAGHTATLRC--SATGSP 3239



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 57/239 (23%), Positives = 82/239 (34%), Gaps = 55/239 (23%)

Query: 323  ELLCNVSGALPPAGRHAAYSVGWEMAPAGAPG---PGRL------VAQLDTEGVGSLGPG 373
            E +C  +  +         SV        APG   P R+      VA+ +T  +  + PG
Sbjct: 2693 EYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPG 2752

Query: 374  YEGRHIAMEKVA--------SRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASA 425
                 +   K          +R  RLRL    P D+G Y C     V GS          
Sbjct: 2753 QAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVC----RVMGS---------- 2798

Query: 426  RSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPE 485
             S PL   V    V +EA             + S   ++   GG P +R+  S    R  
Sbjct: 2799 -SGPLEASVL---VTIEA-------------SGSSAVHVPAPGGAPPIRIEPS--SSRVA 2839

Query: 486  DGELSSVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHC 544
            +G+   +   + G            R G  P   ++ GP    LRL+ + P D G Y C
Sbjct: 2840 EGQTLDLKCVVPGQA--HAQVTWHKRGGNLPARHQVHGP---LLRLNQVSPADSGEYSC 2893


>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
           RhoGEF isoform a [Homo sapiens]
          Length = 6620

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 50/198 (25%), Positives = 74/198 (37%), Gaps = 44/198 (22%)

Query: 239 AAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDV 298
           A    RL ++G D YR+ +     GD+G Y C A   I +            AV   VD 
Sbjct: 52  AGARFRLAQDG-DLYRLTILDLALGDSGQYVCRARNAIGEAFA---------AVGLQVDA 101

Query: 299 QTLSSQLA--VTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPG 356
           +   ++ A    + P   R+  G      C V G+  PA       V W          G
Sbjct: 102 EAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPA-------VSWSK-------DG 147

Query: 357 RLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSG 416
           R + + D            G  + +E++   +  LR+ AARP D GTY   A+  +  + 
Sbjct: 148 RRLGEPD------------GPRVRVEELGEAS-ALRIRAARPRDGGTYEVRAENPLGAAS 194

Query: 417 TRL-----REAASARSRP 429
                    +AA   SRP
Sbjct: 195 AAAALVVDSDAADTASRP 212



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 95/362 (26%), Positives = 125/362 (34%), Gaps = 70/362 (19%)

Query: 65  FLYRPEAPDTALG--------IVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIAR 116
           FL RP+A   ++G        IV     Q S+   +  V AG        GD   L I  
Sbjct: 12  FLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILD 71

Query: 117 LQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTV 176
           L   D+G Y C   +     +G     V L+V     + + A   P     PTS   + V
Sbjct: 72  LALGDSGQYVCRARNA----IGEAFAAVGLQV---DAEAACAEQAPHFLLRPTS---IRV 121

Query: 177 HEGQELALGCLARTSTQKHTHLAVSF---GRSVPEAPVGRSTLQEVVGIRSDLAVEAGAP 233
            EG E    C    S +     AVS+   GR + E P G     E +G  S L + A  P
Sbjct: 122 REGSEATFRCRVGGSPRP----AVSWSKDGRRLGE-PDGPRVRVEELGEASALRIRAARP 176

Query: 234 YAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVL 293
                     R G     R    +G A A  A      AA+    P  S A      A+L
Sbjct: 177 ----------RDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTA------ALL 220

Query: 294 AHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAP 353
           AH+  Q     +     P      P       C V+      G+HA  S        G P
Sbjct: 221 AHL--QRRREAMRAEGAPAS----PPSTGTRTCTVT-----EGKHARLSC----YVTGEP 265

Query: 354 GPGRLV---AQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKA 410
            P  +     QL TEG          RH+  E  A   + L++   +  D G Y C A  
Sbjct: 266 KPETVWKKDGQLVTEG---------RRHVVYED-AQENFVLKILFCKQSDRGLYTCTASN 315

Query: 411 YV 412
            V
Sbjct: 316 LV 317


>gi|148833506 obscurin, cytoskeletal calmodulin and
           titin-interacting RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 50/198 (25%), Positives = 74/198 (37%), Gaps = 44/198 (22%)

Query: 239 AAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDV 298
           A    RL ++G D YR+ +     GD+G Y C A   I +            AV   VD 
Sbjct: 52  AGARFRLAQDG-DLYRLTILDLALGDSGQYVCRARNAIGEAFA---------AVGLQVDA 101

Query: 299 QTLSSQLA--VTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPG 356
           +   ++ A    + P   R+  G      C V G+  PA       V W          G
Sbjct: 102 EAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPA-------VSWSK-------DG 147

Query: 357 RLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSG 416
           R + + D            G  + +E++   +  LR+ AARP D GTY   A+  +  + 
Sbjct: 148 RRLGEPD------------GPRVRVEELGEAS-ALRIRAARPRDGGTYEVRAENPLGAAS 194

Query: 417 TRL-----REAASARSRP 429
                    +AA   SRP
Sbjct: 195 AAAALVVDSDAADTASRP 212



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 95/362 (26%), Positives = 125/362 (34%), Gaps = 70/362 (19%)

Query: 65  FLYRPEAPDTALG--------IVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIAR 116
           FL RP+A   ++G        IV     Q S+   +  V AG        GD   L I  
Sbjct: 12  FLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILD 71

Query: 117 LQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTV 176
           L   D+G Y C   +     +G     V L+V     + + A   P     PTS   + V
Sbjct: 72  LALGDSGQYVCRARNA----IGEAFAAVGLQV---DAEAACAEQAPHFLLRPTS---IRV 121

Query: 177 HEGQELALGCLARTSTQKHTHLAVSF---GRSVPEAPVGRSTLQEVVGIRSDLAVEAGAP 233
            EG E    C    S +     AVS+   GR + E P G     E +G  S L + A  P
Sbjct: 122 REGSEATFRCRVGGSPRP----AVSWSKDGRRLGE-PDGPRVRVEELGEASALRIRAARP 176

Query: 234 YAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVL 293
                     R G     R    +G A A  A      AA+    P  S A      A+L
Sbjct: 177 ----------RDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTA------ALL 220

Query: 294 AHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAP 353
           AH+  Q     +     P      P       C V+      G+HA  S        G P
Sbjct: 221 AHL--QRRREAMRAEGAPAS----PPSTGTRTCTVT-----EGKHARLSC----YVTGEP 265

Query: 354 GPGRLV---AQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKA 410
            P  +     QL TEG          RH+  E  A   + L++   +  D G Y C A  
Sbjct: 266 KPETVWKKDGQLVTEG---------RRHVVYED-AQENFVLKILFCKQSDRGLYTCTASN 315

Query: 411 YV 412
            V
Sbjct: 316 LV 317


>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
           sapiens]
          Length = 848

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 64/300 (21%), Positives = 109/300 (36%), Gaps = 67/300 (22%)

Query: 198 LAVSFGRSVPEAPVGRST--LQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTD--RY 253
           L V    S  E  VG S   L +V G   D  +   +P  E+L   + R+     D    
Sbjct: 20  LQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSS 79

Query: 254 RMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGE 313
            + +  A   DAG Y C     +   DGS ++        A V+V+ +  +L     P  
Sbjct: 80  TLTIYNANIDDAGIYKCV----VTGEDGSESE--------ATVNVK-IFQKLMFKNAPTP 126

Query: 314 RRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPG 373
           +    GE   ++C+V  +LPP       ++ W+                           
Sbjct: 127 QEFREGEDAVIVCDVVSSLPP-------TIIWK--------------------------- 152

Query: 374 YEGRHIAMEK-----VASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSR 428
           ++GR + ++K     V S  Y L++   +  D GTYRC  +   RG     ++     + 
Sbjct: 153 HKGRDVILKKDVRFIVLSNNY-LQIRGIKKTDEGTYRCEGRILARGE-INFKDIQVIVNV 210

Query: 429 PLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGE 488
           P  +  R+          +   T   G++ +L+C+      P          +E+ ED E
Sbjct: 211 PPTIQARQN---------IVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDE 261


>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
           sapiens]
          Length = 858

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 64/300 (21%), Positives = 109/300 (36%), Gaps = 67/300 (22%)

Query: 198 LAVSFGRSVPEAPVGRST--LQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTD--RY 253
           L V    S  E  VG S   L +V G   D  +   +P  E+L   + R+     D    
Sbjct: 20  LQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSS 79

Query: 254 RMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGE 313
            + +  A   DAG Y C     +   DGS ++        A V+V+ +  +L     P  
Sbjct: 80  TLTIYNANIDDAGIYKCV----VTGEDGSESE--------ATVNVK-IFQKLMFKNAPTP 126

Query: 314 RRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPG 373
           +    GE   ++C+V  +LPP       ++ W+                           
Sbjct: 127 QEFREGEDAVIVCDVVSSLPP-------TIIWK--------------------------- 152

Query: 374 YEGRHIAMEK-----VASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSR 428
           ++GR + ++K     V S  Y L++   +  D GTYRC  +   RG     ++     + 
Sbjct: 153 HKGRDVILKKDVRFIVLSNNY-LQIRGIKKTDEGTYRCEGRILARGE-INFKDIQVIVNV 210

Query: 429 PLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGE 488
           P  +  R+          +   T   G++ +L+C+      P          +E+ ED E
Sbjct: 211 PPTIQARQN---------IVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDE 261


>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
           sapiens]
          Length = 761

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 64/300 (21%), Positives = 109/300 (36%), Gaps = 67/300 (22%)

Query: 198 LAVSFGRSVPEAPVGRST--LQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTD--RY 253
           L V    S  E  VG S   L +V G   D  +   +P  E+L   + R+     D    
Sbjct: 20  LQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSS 79

Query: 254 RMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGE 313
            + +  A   DAG Y C     +   DGS ++        A V+V+ +  +L     P  
Sbjct: 80  TLTIYNANIDDAGIYKCV----VTGEDGSESE--------ATVNVK-IFQKLMFKNAPTP 126

Query: 314 RRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPG 373
           +    GE   ++C+V  +LPP       ++ W+                           
Sbjct: 127 QEFREGEDAVIVCDVVSSLPP-------TIIWK--------------------------- 152

Query: 374 YEGRHIAMEK-----VASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSR 428
           ++GR + ++K     V S  Y L++   +  D GTYRC  +   RG     ++     + 
Sbjct: 153 HKGRDVILKKDVRFIVLSNNY-LQIRGIKKTDEGTYRCEGRILARGE-INFKDIQVIVNV 210

Query: 429 PLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGE 488
           P  +  R+          +   T   G++ +L+C+      P          +E+ ED E
Sbjct: 211 PPTIQARQN---------IVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDE 261


>gi|239750758 PREDICTED: hypothetical protein XP_002347493 [Homo
           sapiens]
          Length = 120

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 29/116 (25%), Positives = 51/116 (43%), Gaps = 6/116 (5%)

Query: 15  LLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDT 74
           +L L+    G  A+  LV  G   +  G +V +SC V+GY    + +  W    P     
Sbjct: 7   ILFLVAAATGTHAQVQLVQSGAEVKKPGASVKVSCKVSGYT-LTELSMHWVRQAPGKGLE 65

Query: 75  ALGIVSTKDTQFSYA-VFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHT 129
            +G    +D +  YA  F+ RV       +    D   ++++ L+++D  +Y C T
Sbjct: 66  WMGGFDPEDGETIYAQKFQGRV----TMTEDTSTDTAYMELSSLRSEDTAVYYCAT 117


>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
          Length = 1215

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 71/294 (24%), Positives = 101/294 (34%), Gaps = 97/294 (32%)

Query: 255 MVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGER 314
           +++ G    DAG Y C A   +           ++   L + D  ++S+  AV +     
Sbjct: 545 LIIQGVAPEDAGNYSCQATNEVGTD--------QETVTLYYTDPPSVSAVNAVVL----- 591

Query: 315 RIGPGEPLELLCNVSGALPPAGRHAAYSVGWEM--APAGAPGPGRLVAQLDTEGVGSLGP 372
            +  GE   L+C  SG  PP  R   Y  G EM  AP G                     
Sbjct: 592 -VAVGEEAVLVCEASGVPPP--RVIWYRGGLEMILAPEG--------------------- 627

Query: 373 GYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAA--SARSRPL 430
                        S + +LR+ AA+  DAGTY C A   +  +   ++ A   + +   L
Sbjct: 628 -------------SSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTEL 674

Query: 431 PVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELS 490
           P  V                TV  G +A L C  + R  P       +W   R  DG+  
Sbjct: 675 PRDV----------------TVELGRSALLACRATGRPPP-----TVTW---RRGDGQ-- 708

Query: 491 SVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHC 544
                            LG+R G G  S     P S  L   S+ PED+  Y C
Sbjct: 709 ----------------PLGLRLGAGRGS-RSRQPDSGVLFFESVAPEDQAPYVC 745



 Score = 33.5 bits (75), Expect = 0.59
 Identities = 49/189 (25%), Positives = 67/189 (35%), Gaps = 55/189 (29%)

Query: 227 AVEAGAPYAERLAAGELRLGKE------GTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPD 280
           +V +  P+  +L  GE RLG+E      G   + ++   A   + GTY CTA        
Sbjct: 332 SVHSALPFRLQLRRGEARLGEERHFQESGNSSWEIL--RASKAEEGTYECTAV------- 382

Query: 281 GSWAQIAEKRAVLAHVDVQT-LSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHA 339
            S A     +A +   D    L     VTV PGE  +       L C V G  P    + 
Sbjct: 383 -SRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAV-------LSCRVLGEAP---YNL 431

Query: 340 AYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPG 399
            +   W + PA     GR VAQL                            L +    P 
Sbjct: 432 TWVRDWRVLPAST---GR-VAQL------------------------ADLSLEISGIIPT 463

Query: 400 DAGTYRCLA 408
           D G Y+C+A
Sbjct: 464 DGGRYQCVA 472



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 96/410 (23%), Positives = 141/410 (34%), Gaps = 103/410 (25%)

Query: 112 LKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRV--LPDVLQVSAAPPGPRGRQAPT 169
           L+I   Q +DAG Y C   +     LG  S +++L V   P + ++        GR A  
Sbjct: 633 LRIPAAQERDAGTYTCRAVNE----LGDASAEIQLAVGHAPQLTELPRDVTVELGRSALL 688

Query: 170 S-------PPRMTVHEGQELALGC---LARTSTQKHTHLAVSFGRSVP---EAPV---GR 213
           +       PP +T   G    LG      R S  +     V F  SV    +AP     R
Sbjct: 689 ACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEAR 748

Query: 214 STLQEVVGIRSDLAVEAGAPYAERLAAGELRL--------------GKEGTDRYRMVVGG 259
           +   +V    + L V   AP     +A  +R+              G+   +R+ +  G 
Sbjct: 749 NVFGKVQA-EARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDG- 806

Query: 260 AQAGDAGTYHCTAAEW-------IQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPG 312
            +    G+ H   A+        +Q+  G ++ +A   A   H DV+     L V V P 
Sbjct: 807 -RPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVE-----LVVQVPP- 859

Query: 313 ERRIGP---------GEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLD 363
             RI P         G P  L C  SG   P       ++ W                 +
Sbjct: 860 --RIHPTATHHITNEGVPASLPCVASGVPAP-------TITWTK---------------E 895

Query: 364 TEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAA 423
           T  + S GP Y           S+   L +      DAG Y C A   V  S   +R + 
Sbjct: 896 TNALTSRGPHYN---------VSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSV 946

Query: 424 SARSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGL 473
           + + R      R   V L+        T   GE  +L C    +G PP L
Sbjct: 947 NTKPRIHMNGSRNANVPLQV-------TAKAGEEVTLDC--EAKGSPPPL 987



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 44/171 (25%), Positives = 64/171 (37%), Gaps = 49/171 (28%)

Query: 112  LKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSP 171
            L IA+  AQDAG Y C   +T+T    S   ++ +   P +           G +    P
Sbjct: 914  LLIAQPSAQDAGAYVC--TATNTVGFSSQEMRLSVNTKPRIHM--------NGSRNANVP 963

Query: 172  PRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAG 231
             ++T   G+E+ L C A+ S      L      S P  P+         G+         
Sbjct: 964  LQVTAKAGEEVTLDCEAKGSPPP---LVTWTKDSRPVPPITNR-----YGL--------- 1006

Query: 232  APYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGS 282
                  L +G LRL +             Q GD+G Y CTA+    +P GS
Sbjct: 1007 ------LPSGSLRLAQ------------VQVGDSGHYECTAS----NPAGS 1035



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)

Query: 242 ELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTL 301
           E+ L  EG+   ++ +  AQ  DAGTY C A   + D        AE +  + H      
Sbjct: 620 EMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDAS------AEIQLAVGHAP---- 669

Query: 302 SSQLAVTVGPGERRIGPGEPLELLCNVSGALPP 334
                +T  P +  +  G    L C  +G  PP
Sbjct: 670 ----QLTELPRDVTVELGRSALLACRATGRPPP 698


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 71/294 (24%), Positives = 101/294 (34%), Gaps = 97/294 (32%)

Query: 255 MVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGER 314
           +++ G    DAG Y C A   +           ++   L + D  ++S+  AV +     
Sbjct: 662 LIIQGVAPEDAGNYSCQATNEVGTD--------QETVTLYYTDPPSVSAVNAVVL----- 708

Query: 315 RIGPGEPLELLCNVSGALPPAGRHAAYSVGWEM--APAGAPGPGRLVAQLDTEGVGSLGP 372
            +  GE   L+C  SG  PP  R   Y  G EM  AP G                     
Sbjct: 709 -VAVGEEAVLVCEASGVPPP--RVIWYRGGLEMILAPEG--------------------- 744

Query: 373 GYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAA--SARSRPL 430
                        S + +LR+ AA+  DAGTY C A   +  +   ++ A   + +   L
Sbjct: 745 -------------SSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTEL 791

Query: 431 PVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELS 490
           P  V                TV  G +A L C  + R  P       +W   R  DG+  
Sbjct: 792 PRDV----------------TVELGRSALLACRATGRPPP-----TVTW---RRGDGQ-- 825

Query: 491 SVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHC 544
                            LG+R G G  S     P S  L   S+ PED+  Y C
Sbjct: 826 ----------------PLGLRLGAGRGS-RSRQPDSGVLFFESVAPEDQAPYVC 862



 Score = 36.6 bits (83), Expect = 0.070
 Identities = 90/373 (24%), Positives = 131/373 (35%), Gaps = 84/373 (22%)

Query: 48   SCNVTGYEGPAQQNFEWFLYRPE------APDTALGIVSTK-----------DTQFSYAV 90
            SC      G AQ++F   +  P       A    LG+                 Q  +  
Sbjct: 1385 SCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTK 1444

Query: 91   FKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKV------ 144
             +  V+ G   +Q +Q D  VL+I      D G Y+C   S   +    +  +V      
Sbjct: 1445 DRQPVLPGGPHLQ-VQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTI 1503

Query: 145  -------ELRVLPD----VLQVSAAPPGPR------GRQAPTSPPRMTVHEGQELALG-- 185
                   E+ V+ D    +L  +   P P       G   PTS   +    G++L LG  
Sbjct: 1504 WGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRA 1563

Query: 186  ---------CLART---STQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDL--AVEAG 231
                     C A     + +K T L V    ++ E   GR  + + V  R      V  G
Sbjct: 1564 QSSDAGVYTCKASNAVGAAEKATRLDVYVPPTI-EGAGGRPYVVKAVAGRPVALECVARG 1622

Query: 232  AP------YAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQ 285
             P      + E L   E    +  TD   + +       +G Y C A+     P G    
Sbjct: 1623 HPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS----SPAG---- 1674

Query: 286  IAEKRAVLAH-VDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPA------GRH 338
                 AVL + V+VQ +  QL V  G G+     G+PLEL C  SG+  P       GR 
Sbjct: 1675 ----EAVLQYSVEVQ-VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRP 1729

Query: 339  AAYSVGWEMAPAG 351
            A    G ++A  G
Sbjct: 1730 AEELAGVQVASQG 1742



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 66/276 (23%), Positives = 97/276 (35%), Gaps = 66/276 (23%)

Query: 105  LQGDAVVLKIARLQAQDAGIYEC--HTPSTDTRYLGSY--------------SGKVELR- 147
            L G ++VLK   L+A DAG Y C  H P+ +   L +               SG +  R 
Sbjct: 3270 LDGGSLVLK--GLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRP 3327

Query: 148  --VLPDVLQVSAAPPG-----PRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAV 200
              ++  V  V  +PP        G   P S   +    G  L +  +        T +A 
Sbjct: 3328 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 3387

Query: 201  SFGRSVPEAPVGRS-TLQ-------EVVGIRSDLAVEAGA-------------PYAERLA 239
            S     P     R+ TLQ       E V  ++D+ V  G+             P    + 
Sbjct: 3388 S-----PAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK 3442

Query: 240  AGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQ 299
             GE  L +       + +    AGD+GTY C A             ++E      H  + 
Sbjct: 3443 DGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVA-------------VSEAGEARRHFQLT 3489

Query: 300  TLSSQLAVTVG-PGERRIGPGEPLELLCNVSGALPP 334
             +        G P E  + PG P+ELLC+  G   P
Sbjct: 3490 VMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQP 3525



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 86/365 (23%), Positives = 129/365 (35%), Gaps = 96/365 (26%)

Query: 96   VAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRV-LPDVLQ 154
            VA  V  Q L G    L+IA    +DAG Y C   ++     GS  GK  L V +P V++
Sbjct: 3988 VATGVSTQVLPGGQ--LRIAHASPEDAGNYLCIAKNS----AGSAMGKTRLVVQVPPVIE 4041

Query: 155  VSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRS 214
                             P ++  EG    L C AR S + +       G+ V  A  G+ 
Sbjct: 4042 --------------NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKD-GQPVSGAE-GKF 4085

Query: 215  TLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAE 274
            T+Q                      +GEL            +V   +  DAGTY CTA  
Sbjct: 4086 TIQP---------------------SGEL------------LVKNLEGQDAGTYTCTAEN 4112

Query: 275  WIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPP 334
             +          A +R    H+ +  L      T  PG+R +  G+ L L C   G+  P
Sbjct: 4113 AVGR--------ARRR---VHLTILVLP---VFTTLPGDRSLRLGDRLWLRCAARGSPTP 4158

Query: 335  AGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLE 394
                    +GW +                TEGV     G   +  A+ +  S TY    E
Sbjct: 4159 -------RIGWTVNDRPV-----------TEGVSEQDGGSTLQRAAVSREDSGTYVCWAE 4200

Query: 395  AARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVV----LEAVAWLAGG 450
                   G  + ++  +V+ +     EA S    P+   ++ + VV    +  + W+  G
Sbjct: 4201 ----NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDG 4256

Query: 451  TVYRG 455
               RG
Sbjct: 4257 LPLRG 4261



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 97/435 (22%), Positives = 141/435 (32%), Gaps = 81/435 (18%)

Query: 112  LKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSP 171
            L IA+  AQDAG Y C    T T  +G  S   E+R+  + L +S       G     S 
Sbjct: 1031 LLIAQPSAQDAGAYVC----TATNTVGFSS--QEMRLSVNRLALSKYVWEEYGLLPSGSL 1084

Query: 172  PRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAG 231
                V  G      C A       +H  V   +  P+   G   L+ +VG   DL   A 
Sbjct: 1085 RLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAE 1144

Query: 232  APYAERLAAGELRLGKEGTDRYRMV-VGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKR 290
                 +L+  +  +  +G      V     +  DAG Y C A+                 
Sbjct: 1145 GNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASN---------------- 1188

Query: 291  AVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALP-PAGRHAAYSVGWEMAP 349
                   V     +L V   P          LE +   + +LP PA       V W   P
Sbjct: 1189 ----SAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKPQVTWRKGP 1244

Query: 350  AGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAK 409
            +  P  G+        GV  L  G                 L L +  P D+G Y C A 
Sbjct: 1245 SSEPLHGQ-------PGVAVLEEG----------------SLFLASVSPADSGDYECQAT 1281

Query: 410  AYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGG 469
              V  +  R +         +P  +RE+G         A  +   G++ +L C+ +    
Sbjct: 1282 NEVGSTSRRAKLVVY-----VPPSIREDG-------RKANVSGMAGQSLTLECDAN---- 1325

Query: 470  PPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRL 529
              G  +    W+   +D +L  VP          G A  G   G G V    +      L
Sbjct: 1326 --GFPVPEIVWL---KDAQLVGVPL---------GWAGYGWDLGWGQVGGHRLLDEGQSL 1371

Query: 530  RLHSLGPEDEGVYHC 544
                +   D G+Y C
Sbjct: 1372 HFPRIQEGDSGLYSC 1386



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 107/497 (21%), Positives = 162/497 (32%), Gaps = 149/497 (29%)

Query: 112  LKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSP 171
            L++ R +  D+G+Y C   +   R                ++Q+S   P P  RQAP  P
Sbjct: 2993 LQLGRARLSDSGMYTCEALNAAGRD-------------QKLVQLSVLVP-PAFRQAPRGP 3038

Query: 172  P-RMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEA 230
               + V  G +  L C                  ++PE  V                 + 
Sbjct: 3039 QDAVLVRVGDKAVLSCETD---------------ALPEPTV--------------TWYKD 3069

Query: 231  GAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKR 290
            G P         LR G+      R+ +  AQ  D G Y C  +    +   ++    +  
Sbjct: 3070 GQPLVLAQRTQALRGGQ------RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVP 3123

Query: 291  AVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPA 350
                +   +T+S Q+A            G PL L C+VSG   P       +V W     
Sbjct: 3124 PTFENPKTETVS-QVA------------GSPLVLTCDVSGVPAP-------TVTW----- 3158

Query: 351  GAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAK- 409
                   L  ++  E              A+  V SR  RL+L   +P  AGTY C+A+ 
Sbjct: 3159 -------LKDRMPVESS------------AVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 3199

Query: 410  ----------------AYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVY 453
                              +R SG   RE      + + +    +G     VAWL  G+  
Sbjct: 3200 TQAEARKDFVVAVLVAPRIRSSGV-AREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPL 3258

Query: 454  RGETASLLCNISVRGGP---PGLRL----AASWWVERP--EDGELSSVPAQLVGGV--GQ 502
             G+         + GG     GLR     A +     P  ED  L +V   +   +  G 
Sbjct: 3259 -GQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGA 3317

Query: 503  DGVAELGVRP-----------GGGPVSVE--------------LVGPRSHRLRLHSLGPE 537
            DG   L  RP           G  P+ V               L+    H LR+  +   
Sbjct: 3318 DGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLA 3377

Query: 538  DEGVYHCAPSAWVQHAD 554
            D G++ C  ++    AD
Sbjct: 3378 DAGIFTCVAASPAGVAD 3394



 Score = 33.9 bits (76), Expect = 0.45
 Identities = 46/156 (29%), Positives = 63/156 (40%), Gaps = 15/156 (9%)

Query: 391  LRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRP---LPVHVREEGVVLEAVAWL 447
            LR+E A+  DAG+YRC+A + V GS T LR        P   LP  +    +V   V   
Sbjct: 1941 LRIEQAQLSDAGSYRCVA-SNVAGS-TELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLT 1998

Query: 448  AGGTVYRGETASLLCN---ISVRGGP-----PGLRLAASWWVERPEDGELSSVPAQLVGG 499
               T     T   L +   +S  G P     PG R+         + G  S V    VG 
Sbjct: 1999 CNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGE 2058

Query: 500  VGQDGVAELGVRPG--GGPVSVELVGPRSHRLRLHS 533
              QD V ++ + P   G  ++V +V   S  L   S
Sbjct: 2059 DRQDVVLQVHMPPSILGEELNVSVVANESVALECQS 2094



 Score = 33.5 bits (75), Expect = 0.59
 Identities = 49/189 (25%), Positives = 67/189 (35%), Gaps = 55/189 (29%)

Query: 227 AVEAGAPYAERLAAGELRLGKE------GTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPD 280
           +V +  P+  +L  GE RLG+E      G   + ++   A   + GTY CTA        
Sbjct: 449 SVHSALPFRLQLRRGEARLGEERHFQESGNSSWEIL--RASKAEEGTYECTAV------- 499

Query: 281 GSWAQIAEKRAVLAHVDVQT-LSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHA 339
            S A     +A +   D    L     VTV PGE  +       L C V G  P    + 
Sbjct: 500 -SRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAV-------LSCRVLGEAP---YNL 548

Query: 340 AYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPG 399
            +   W + PA     GR VAQL                            L +    P 
Sbjct: 549 TWVRDWRVLPAST---GR-VAQL------------------------ADLSLEISGIIPT 580

Query: 400 DAGTYRCLA 408
           D G Y+C+A
Sbjct: 581 DGGRYQCVA 589



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)

Query: 242 ELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTL 301
           E+ L  EG+   ++ +  AQ  DAGTY C A   + D        AE +  + H      
Sbjct: 737 EMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDAS------AEIQLAVGHAP---- 786

Query: 302 SSQLAVTVGPGERRIGPGEPLELLCNVSGALPP 334
                +T  P +  +  G    L C  +G  PP
Sbjct: 787 ----QLTELPRDVTVELGRSALLACRATGRPPP 815


>gi|67188443 CD276 antigen isoform a [Homo sapiens]
          Length = 534

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 91/409 (22%), Positives = 141/409 (34%), Gaps = 79/409 (19%)

Query: 27  AREVLVPEGPLYRVAGTAVSISCNVTGYEG--PAQQNFEWFLYRPEAPDTALGIVSTKDT 84
           A EV VPE P+  + GT  ++ C+ +   G   AQ N  W     +  DT   + S  + 
Sbjct: 28  ALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIW-----QLTDTKQLVHSFAEG 82

Query: 85  QFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKV 144
           Q   + + +R       +   QG+A  L++ R++  D G + C     D       S  V
Sbjct: 83  QDQGSAYANRTALFPDLL--AQGNA-SLRLQRVRVADEGSFTCFVSIRDFG-----SAAV 134

Query: 145 ELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGR 204
            L+V                  AP S P MT+   ++L  G     +   +        +
Sbjct: 135 SLQV-----------------AAPYSKPSMTLEPNKDLRPGDTVTITCSSY--------Q 169

Query: 205 SVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGEL--RLGKEGTDRYRMVVGGAQA 262
             PEA V     Q             G P    +   ++    G         VV GA  
Sbjct: 170 GYPEAEVFWQDGQ-------------GVPLTGNVTTSQMANEQGLFDVHSILRVVLGAN- 215

Query: 263 GDAGTYHCTAAEWIQDPDG-SWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEP 321
              GTY C     +   D  S   I  +R+    V+VQ     +   V         G  
Sbjct: 216 ---GTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALV---------GTD 263

Query: 322 LELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGR-HIA 380
             L C+ S    P    A  ++ W++         + +    TEG    G  Y  R  + 
Sbjct: 264 ATLRCSFSP--EPGFSLAQLNLIWQLTDT------KQLVHSFTEG-RDQGSAYANRTALF 314

Query: 381 MEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRP 429
            + +A     LRL+  R  D G++ C       GS     + A+  S+P
Sbjct: 315 PDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKP 363



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 40/161 (24%), Positives = 64/161 (39%), Gaps = 32/161 (19%)

Query: 27  AREVLVPEGPLYRVAGTAVSISCNVTGYEG--PAQQNFEWFLYRPEAPDTALGIVSTKDT 84
           A EV VPE P+  + GT  ++ C+ +   G   AQ N  W     +  DT   + S  + 
Sbjct: 246 AVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIW-----QLTDTKQLVHSFTEG 300

Query: 85  QFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKV 144
           +   + + +R       +   QG+A  L++ R++  D G + C     D       S  V
Sbjct: 301 RDQGSAYANRTALFPDLL--AQGNA-SLRLQRVRVADEGSFTCFVSIRDFG-----SAAV 352

Query: 145 ELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALG 185
            L+V                  AP S P MT+   ++L  G
Sbjct: 353 SLQV-----------------AAPYSKPSMTLEPNKDLRPG 376


>gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]
          Length = 428

 Score = 38.5 bits (88), Expect = 0.018
 Identities = 42/186 (22%), Positives = 66/186 (35%), Gaps = 41/186 (22%)

Query: 13  LPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAP 72
           LP LLLL+    C   E+ +   P +   G+ V+++C                       
Sbjct: 2   LPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCK---------------------- 39

Query: 73  DTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPST 132
              +  + + D QF +  F+     G          +  L+IA +  +D G Y C   + 
Sbjct: 40  ---MPFLQSSDAQFQFCFFRDTRALGPG-----WSSSPKLQIAAMWKEDTGSYWCEAQTM 91

Query: 133 DTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTST 192
            ++ L S   ++ +  +P V  VS            T PP   V EG  L L C     T
Sbjct: 92  ASKVLRSRRSQINVHRVP-VADVS----------LETQPPGGQVMEGDRLVLICSVAMGT 140

Query: 193 QKHTHL 198
              T L
Sbjct: 141 GDITFL 146


>gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]
          Length = 366

 Score = 38.5 bits (88), Expect = 0.018
 Identities = 42/186 (22%), Positives = 66/186 (35%), Gaps = 41/186 (22%)

Query: 13  LPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAP 72
           LP LLLL+    C   E+ +   P +   G+ V+++C                       
Sbjct: 2   LPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCK---------------------- 39

Query: 73  DTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPST 132
              +  + + D QF +  F+     G          +  L+IA +  +D G Y C   + 
Sbjct: 40  ---MPFLQSSDAQFQFCFFRDTRALGPG-----WSSSPKLQIAAMWKEDTGSYWCEAQTM 91

Query: 133 DTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTST 192
            ++ L S   ++ +  +P V  VS            T PP   V EG  L L C     T
Sbjct: 92  ASKVLRSRRSQINVHRVP-VADVS----------LETQPPGGQVMEGDRLVLICSVAMGT 140

Query: 193 QKHTHL 198
              T L
Sbjct: 141 GDITFL 146


>gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]
          Length = 429

 Score = 38.5 bits (88), Expect = 0.018
 Identities = 42/186 (22%), Positives = 66/186 (35%), Gaps = 41/186 (22%)

Query: 13  LPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAP 72
           LP LLLL+    C   E+ +   P +   G+ V+++C                       
Sbjct: 2   LPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCK---------------------- 39

Query: 73  DTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPST 132
              +  + + D QF +  F+     G          +  L+IA +  +D G Y C   + 
Sbjct: 40  ---MPFLQSSDAQFQFCFFRDTRALGPG-----WSSSPKLQIAAMWKEDTGSYWCEAQTM 91

Query: 133 DTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTST 192
            ++ L S   ++ +  +P V  VS            T PP   V EG  L L C     T
Sbjct: 92  ASKVLRSRRSQINVHRVP-VADVS----------LETQPPGGQVMEGDRLVLICSVAMGT 140

Query: 193 QKHTHL 198
              T L
Sbjct: 141 GDITFL 146


>gi|46094014 peptide chain release factor 3 [Homo sapiens]
          Length = 628

 Score = 38.5 bits (88), Expect = 0.018
 Identities = 44/196 (22%), Positives = 70/196 (35%), Gaps = 28/196 (14%)

Query: 139 SYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHL 198
           ++S K+ +   P V  V AA   P   + PT PP +    G          T T      
Sbjct: 47  AFSRKLNVNAKPFVPNVHAAEFVPSFLRGPTQPPTLPAGSGSN------DETCTGAGYPQ 100

Query: 199 AVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVV- 257
               GR  P  P     L  + G  S + +E   P  E    GE+ +  E +  +   V 
Sbjct: 101 GKRMGRGAPVEPSREEPLVSLEGSNSAVTMELSEPVVEN---GEVEMALEESWEHSKEVS 157

Query: 258 ----GGAQAGDAGTYHCTAAEWIQD------------PDGSWAQIAEKRAVLAHVDV--Q 299
               GG  +GD+G    +  E +++            P G+  +       + HVD    
Sbjct: 158 EAEPGGGSSGDSGPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKS 217

Query: 300 TLSSQLAVTVGPGERR 315
           T+  Q+    G  ++R
Sbjct: 218 TIGGQIMFLTGMVDKR 233


>gi|189571583 intercellular adhesion molecule 5 precursor [Homo
           sapiens]
          Length = 924

 Score = 37.0 bits (84), Expect = 0.053
 Identities = 100/382 (26%), Positives = 137/382 (35%), Gaps = 83/382 (21%)

Query: 130 PSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLAR 189
           P    + +GS  G  E  +LP       APP P  R AP  P        + LA G    
Sbjct: 602 PQPSVKCVGS-GGATEGVLLP------LAPPDPSPR-APRIP--------RVLAPGIYVC 645

Query: 190 TSTQKHTHLAVSFGRSVPEAP-VGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKE 248
            +T +H  +A +   S    P +  ST              A A  A    +  +R  +E
Sbjct: 646 NATNRHGSVAKTVVVSAESPPEMDESTCPSHQTWLEGAEASALACAARGRPSPGVRCSRE 705

Query: 249 GT---DRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQL 305
           G    ++ R+        DAGTYHC A           A   + R V   V+ + + ++L
Sbjct: 706 GIPWPEQQRV-----SREDAGTYHCVATN---------AHGTDSRTVTVGVEYRPVVAEL 751

Query: 306 AVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLV--AQLD 363
           A +   G R   PG    L C    A PPA       + W  AP GA   G     + L 
Sbjct: 752 AASPPGGVR---PGGNFTLTCRAE-AWPPA------QISWR-APPGALNIGLSSNNSTLS 800

Query: 364 TEG-VGSLGPGYE-------GRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGS 415
             G +GS G  YE       GRH    ++  R     L  A  G AG    LA     G+
Sbjct: 801 VAGAMGSHGGEYECAATNAHGRH--ARRITVRVAGPWLWVAVGGAAGGAALLA----AGA 854

Query: 416 GTRLREAASARSRPLPVHVRE-----EGVVLEAVAWLAGGTVYRGETASLLCNISVRGGP 470
           G      ++A  +    +V+E     E V L      AGG                 GGP
Sbjct: 855 GLAFYVQSTACKKG-EYNVQEAESSGEAVCLNGAGGGAGGAA------------GAEGGP 901

Query: 471 PGLRLAASWWVERPEDGELSSV 492
                AA    E P +GE+ ++
Sbjct: 902 E----AAGGAAESPAEGEVFAI 919


>gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo
           sapiens]
          Length = 523

 Score = 37.0 bits (84), Expect = 0.053
 Identities = 31/124 (25%), Positives = 54/124 (43%), Gaps = 8/124 (6%)

Query: 9   LPPSLPLLLLLMLGMGCWARE----VLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEW 64
           LP SL LLLLL+L   C        V+ P  P+  + G   ++ C+++  +        W
Sbjct: 11  LPASLLLLLLLLLLSLCALVSAQFTVVGPANPILAMVGENTTLRCHLSPEKNAEDMEVRW 70

Query: 65  FLYRPEAPDTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGI 124
           F  +  +P   +     + T+     ++ R+      + R    +V L I  + AQ+ GI
Sbjct: 71  FRSQ-FSPAVFVYKGGRERTEEQMEEYRGRITFVSKDINR---GSVALVIHNVTAQENGI 126

Query: 125 YECH 128
           Y C+
Sbjct: 127 YRCY 130


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 36.6 bits (83), Expect = 0.070
 Identities = 90/373 (24%), Positives = 131/373 (35%), Gaps = 84/373 (22%)

Query: 48  SCNVTGYEGPAQQNFEWFLYRPE------APDTALGIVSTK-----------DTQFSYAV 90
           SC      G AQ++F   +  P       A    LG+                 Q  +  
Sbjct: 103 SCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTK 162

Query: 91  FKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKV------ 144
            +  V+ G   +Q +Q D  VL+I      D G Y+C   S   +    +  +V      
Sbjct: 163 DRQPVLPGGPHLQ-VQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTI 221

Query: 145 -------ELRVLPD----VLQVSAAPPGPR------GRQAPTSPPRMTVHEGQELALG-- 185
                  E+ V+ D    +L  +   P P       G   PTS   +    G++L LG  
Sbjct: 222 WGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRA 281

Query: 186 ---------CLART---STQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDL--AVEAG 231
                    C A     + +K T L V    ++ E   GR  + + V  R      V  G
Sbjct: 282 QSSDAGVYTCKASNAVGAAEKATRLDVYVPPTI-EGAGGRPYVVKAVAGRPVALECVARG 340

Query: 232 AP------YAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQ 285
            P      + E L   E    +  TD   + +       +G Y C A+     P G    
Sbjct: 341 HPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS----SPAG---- 392

Query: 286 IAEKRAVLAH-VDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPA------GRH 338
                AVL + V+VQ +  QL V  G G+     G+PLEL C  SG+  P       GR 
Sbjct: 393 ----EAVLQYSVEVQ-VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRP 447

Query: 339 AAYSVGWEMAPAG 351
           A    G ++A  G
Sbjct: 448 AEELAGVQVASQG 460



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 66/276 (23%), Positives = 97/276 (35%), Gaps = 66/276 (23%)

Query: 105  LQGDAVVLKIARLQAQDAGIYEC--HTPSTDTRYLGSY--------------SGKVELR- 147
            L G ++VLK   L+A DAG Y C  H P+ +   L +               SG +  R 
Sbjct: 1988 LDGGSLVLK--GLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRP 2045

Query: 148  --VLPDVLQVSAAPPG-----PRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAV 200
              ++  V  V  +PP        G   P S   +    G  L +  +        T +A 
Sbjct: 2046 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 2105

Query: 201  SFGRSVPEAPVGRS-TLQ-------EVVGIRSDLAVEAGA-------------PYAERLA 239
            S     P     R+ TLQ       E V  ++D+ V  G+             P    + 
Sbjct: 2106 S-----PAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK 2160

Query: 240  AGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQ 299
             GE  L +       + +    AGD+GTY C A             ++E      H  + 
Sbjct: 2161 DGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVA-------------VSEAGEARRHFQLT 2207

Query: 300  TLSSQLAVTVG-PGERRIGPGEPLELLCNVSGALPP 334
             +        G P E  + PG P+ELLC+  G   P
Sbjct: 2208 VMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQP 2243



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 86/365 (23%), Positives = 129/365 (35%), Gaps = 96/365 (26%)

Query: 96   VAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRV-LPDVLQ 154
            VA  V  Q L G    L+IA    +DAG Y C   ++     GS  GK  L V +P V++
Sbjct: 2706 VATGVSTQVLPGGQ--LRIAHASPEDAGNYLCIAKNS----AGSAMGKTRLVVQVPPVIE 2759

Query: 155  VSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRS 214
                             P ++  EG    L C AR S + +       G+ V  A  G+ 
Sbjct: 2760 --------------NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKD-GQPVSGAE-GKF 2803

Query: 215  TLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAE 274
            T+Q                      +GEL            +V   +  DAGTY CTA  
Sbjct: 2804 TIQP---------------------SGEL------------LVKNLEGQDAGTYTCTAEN 2830

Query: 275  WIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPP 334
             +          A +R    H+ +  L      T  PG+R +  G+ L L C   G+  P
Sbjct: 2831 AVGR--------ARRR---VHLTILVLP---VFTTLPGDRSLRLGDRLWLRCAARGSPTP 2876

Query: 335  AGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLE 394
                    +GW +                TEGV     G   +  A+ +  S TY    E
Sbjct: 2877 -------RIGWTVNDRPV-----------TEGVSEQDGGSTLQRAAVSREDSGTYVCWAE 2918

Query: 395  AARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVV----LEAVAWLAGG 450
                   G  + ++  +V+ +     EA S    P+   ++ + VV    +  + W+  G
Sbjct: 2919 ----NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDG 2974

Query: 451  TVYRG 455
               RG
Sbjct: 2975 LPLRG 2979



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 107/497 (21%), Positives = 162/497 (32%), Gaps = 149/497 (29%)

Query: 112  LKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSP 171
            L++ R +  D+G+Y C   +   R                ++Q+S   P P  RQAP  P
Sbjct: 1711 LQLGRARLSDSGMYTCEALNAAGRD-------------QKLVQLSVLVP-PAFRQAPRGP 1756

Query: 172  P-RMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEA 230
               + V  G +  L C                  ++PE  V                 + 
Sbjct: 1757 QDAVLVRVGDKAVLSCETD---------------ALPEPTV--------------TWYKD 1787

Query: 231  GAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKR 290
            G P         LR G+      R+ +  AQ  D G Y C  +    +   ++    +  
Sbjct: 1788 GQPLVLAQRTQALRGGQ------RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVP 1841

Query: 291  AVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPA 350
                +   +T+S Q+A            G PL L C+VSG   P       +V W     
Sbjct: 1842 PTFENPKTETVS-QVA------------GSPLVLTCDVSGVPAP-------TVTW----- 1876

Query: 351  GAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAK- 409
                   L  ++  E              A+  V SR  RL+L   +P  AGTY C+A+ 
Sbjct: 1877 -------LKDRMPVESS------------AVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 1917

Query: 410  ----------------AYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVY 453
                              +R SG   RE      + + +    +G     VAWL  G+  
Sbjct: 1918 TQAEARKDFVVAVLVAPRIRSSGV-AREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPL 1976

Query: 454  RGETASLLCNISVRGGP---PGLRL----AASWWVERP--EDGELSSVPAQLVGGV--GQ 502
             G+         + GG     GLR     A +     P  ED  L +V   +   +  G 
Sbjct: 1977 -GQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGA 2035

Query: 503  DGVAELGVRP-----------GGGPVSVE--------------LVGPRSHRLRLHSLGPE 537
            DG   L  RP           G  P+ V               L+    H LR+  +   
Sbjct: 2036 DGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLA 2095

Query: 538  DEGVYHCAPSAWVQHAD 554
            D G++ C  ++    AD
Sbjct: 2096 DAGIFTCVAASPAGVAD 2112



 Score = 33.9 bits (76), Expect = 0.45
 Identities = 46/156 (29%), Positives = 63/156 (40%), Gaps = 15/156 (9%)

Query: 391 LRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRP---LPVHVREEGVVLEAVAWL 447
           LR+E A+  DAG+YRC+A + V GS T LR        P   LP  +    +V   V   
Sbjct: 659 LRIEQAQLSDAGSYRCVA-SNVAGS-TELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLT 716

Query: 448 AGGTVYRGETASLLCN---ISVRGGP-----PGLRLAASWWVERPEDGELSSVPAQLVGG 499
              T     T   L +   +S  G P     PG R+         + G  S V    VG 
Sbjct: 717 CNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGE 776

Query: 500 VGQDGVAELGVRPG--GGPVSVELVGPRSHRLRLHS 533
             QD V ++ + P   G  ++V +V   S  L   S
Sbjct: 777 DRQDVVLQVHMPPSILGEELNVSVVANESVALECQS 812


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,388,292
Number of Sequences: 37866
Number of extensions: 1465769
Number of successful extensions: 6892
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 81
Number of HSP's that attempted gapping in prelim test: 6099
Number of HSP's gapped (non-prelim): 722
length of query: 613
length of database: 18,247,518
effective HSP length: 108
effective length of query: 505
effective length of database: 14,157,990
effective search space: 7149784950
effective search space used: 7149784950
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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