BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|161377472 cyclin A1 isoform c [Homo sapiens] (421 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|161377472 cyclin A1 isoform c [Homo sapiens] 847 0.0 gi|161377470 cyclin A1 isoform c [Homo sapiens] 847 0.0 gi|161377468 cyclin A1 isoform b [Homo sapiens] 847 0.0 gi|4502611 cyclin A1 isoform a [Homo sapiens] 847 0.0 gi|4502613 cyclin A [Homo sapiens] 348 4e-96 gi|4757930 cyclin B2 [Homo sapiens] 184 1e-46 gi|14327896 cyclin B1 [Homo sapiens] 172 4e-43 gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 160 2e-39 gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 119 4e-27 gi|118572588 cyclin F [Homo sapiens] 112 5e-25 gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 105 6e-23 gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 105 6e-23 gi|17318565 cyclin E2 [Homo sapiens] 103 4e-22 gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 101 1e-21 gi|153791755 cyclin domain containing [Homo sapiens] 100 4e-21 gi|16950655 cyclin D1 [Homo sapiens] 93 4e-19 gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 91 2e-18 gi|4502617 cyclin D2 [Homo sapiens] 88 1e-17 gi|197276674 cyclin J isoform 1 [Homo sapiens] 78 2e-14 gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 73 6e-13 gi|40254889 cyclin J isoform 2 [Homo sapiens] 66 7e-11 gi|197276676 cyclin J isoform 3 [Homo sapiens] 65 9e-11 gi|40805832 cyclin G1 [Homo sapiens] 55 2e-07 gi|4757934 cyclin G1 [Homo sapiens] 55 2e-07 gi|4757936 cyclin G2 [Homo sapiens] 54 3e-07 gi|5802992 cyclin I [Homo sapiens] 46 6e-05 gi|94680985 cyclin J-like [Homo sapiens] 46 7e-05 gi|89886237 cyclin I family, member 2 [Homo sapiens] 45 1e-04 gi|150417989 cyclin K isoform 1 [Homo sapiens] 40 0.003 gi|38176158 cyclin K isoform 2 [Homo sapiens] 40 0.003 >gi|161377472 cyclin A1 isoform c [Homo sapiens] Length = 421 Score = 847 bits (2187), Expect = 0.0 Identities = 421/421 (100%), Positives = 421/421 (100%) Query: 1 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 60 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI Sbjct: 1 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 60 Query: 61 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 120 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV Sbjct: 61 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 120 Query: 121 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 180 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI Sbjct: 121 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 180 Query: 181 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 240 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG Sbjct: 181 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 240 Query: 241 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 300 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT Sbjct: 241 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 300 Query: 301 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 360 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW Sbjct: 301 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 360 Query: 361 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL Sbjct: 361 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420 Query: 421 Q 421 Q Sbjct: 421 Q 421 >gi|161377470 cyclin A1 isoform c [Homo sapiens] Length = 421 Score = 847 bits (2187), Expect = 0.0 Identities = 421/421 (100%), Positives = 421/421 (100%) Query: 1 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 60 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI Sbjct: 1 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 60 Query: 61 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 120 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV Sbjct: 61 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 120 Query: 121 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 180 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI Sbjct: 121 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 180 Query: 181 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 240 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG Sbjct: 181 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 240 Query: 241 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 300 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT Sbjct: 241 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 300 Query: 301 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 360 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW Sbjct: 301 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 360 Query: 361 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL Sbjct: 361 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420 Query: 421 Q 421 Q Sbjct: 421 Q 421 >gi|161377468 cyclin A1 isoform b [Homo sapiens] Length = 464 Score = 847 bits (2187), Expect = 0.0 Identities = 421/421 (100%), Positives = 421/421 (100%) Query: 1 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 60 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI Sbjct: 44 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 103 Query: 61 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 120 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV Sbjct: 104 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 163 Query: 121 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 180 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI Sbjct: 164 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 223 Query: 181 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 240 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG Sbjct: 224 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 283 Query: 241 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 300 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT Sbjct: 284 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 343 Query: 301 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 360 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW Sbjct: 344 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 403 Query: 361 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL Sbjct: 404 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 463 Query: 421 Q 421 Q Sbjct: 464 Q 464 >gi|4502611 cyclin A1 isoform a [Homo sapiens] Length = 465 Score = 847 bits (2187), Expect = 0.0 Identities = 421/421 (100%), Positives = 421/421 (100%) Query: 1 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 60 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI Sbjct: 45 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 104 Query: 61 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 120 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV Sbjct: 105 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 164 Query: 121 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 180 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI Sbjct: 165 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 224 Query: 181 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 240 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG Sbjct: 225 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 284 Query: 241 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 300 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT Sbjct: 285 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 344 Query: 301 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 360 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW Sbjct: 345 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 404 Query: 361 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL Sbjct: 405 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 464 Query: 421 Q 421 Q Sbjct: 465 Q 465 >gi|4502613 cyclin A [Homo sapiens] Length = 432 Score = 348 bits (894), Expect = 4e-96 Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%) Query: 91 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 143 F I++DE E+ + + + + ED ++ G K L + +D + SP + Sbjct: 99 FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158 Query: 144 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 203 D S++ + E S+ V +Y E+I+ YLRE E++ +PK YMKKQPDIT MR IL Sbjct: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214 Query: 204 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 263 VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE Sbjct: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274 Query: 264 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 322 V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL PT NQFL QY L +Q + E+LA Sbjct: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334 Query: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 382 ++ ELSL++ADP+LKYLPS+IA AAF LA YTV WPE+L TGY+L + PCL +L Sbjct: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394 Query: 383 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420 H+ YL P QQ+IREKYK SKY VSL+ PP L L Sbjct: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432 >gi|4757930 cyclin B2 [Homo sapiens] Length = 398 Score = 184 bits (468), Expect = 1e-46 Identities = 107/270 (39%), Positives = 164/270 (60%), Gaps = 5/270 (1%) Query: 146 SLLSQSEDISSLGTDVINV-TEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILV 204 +LL + EDI + + + ++Y ++IYQYLR+ E+ H++ + DI MR ILV Sbjct: 112 ALLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGR-DINGRMRAILV 170 Query: 205 DWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEV 264 DWLV+V +++L ETLY+ V +DRFL V R KLQLVG A+LLASKYEE++ P + Sbjct: 171 DWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNI 230 Query: 265 DEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYV 324 ++FVYITD+ YT Q+ +ME L+LK L F+L P FL + + V V LAKY+ Sbjct: 231 EDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYL 290 Query: 325 AELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHK 384 EL+L++ D + Y PS +AAAA CL+ + + W +TGY+ +E++ + + K Sbjct: 291 MELTLIDYD-MVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAK 349 Query: 385 AYLDIPHRPQQ--AIREKYKASKYLCVSLM 412 + + + AI+ KY +SK L +S++ Sbjct: 350 NVVKVNENLTKFIAIKNKYASSKLLKISMI 379 >gi|14327896 cyclin B1 [Homo sapiens] Length = 433 Score = 172 bits (437), Expect = 4e-43 Identities = 96/257 (37%), Positives = 149/257 (57%), Gaps = 4/257 (1%) Query: 158 GTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLR 217 G D +EY ++IY YLR+ E + Y+ + ++T MR IL+DWLV+V +++L Sbjct: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGNMRAILIDWLVQVQMKFRLL 219 Query: 218 AETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTK 277 ET+Y+ V+ +DRF+ V + LQLVG AM +ASKYEE+YPPE+ +F ++TD+TYTK Sbjct: 220 QETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTK 279 Query: 278 RQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLK 337 Q+ +ME +L+ L F L P FL + + V V LAKY+ EL++L+ D + Sbjct: 280 HQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYD-MVH 338 Query: 338 YLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPH--RPQQ 395 + PS IAA AFCLA ++ W TL + Y+ ++P + L K + + Sbjct: 339 FPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHM 398 Query: 396 AIREKYKASKYLCVSLM 412 ++ KY SK+ +S + Sbjct: 399 TVKNKYATSKHAKISTL 415 >gi|90669307 cyclin B3 isoform 3 [Homo sapiens] Length = 1395 Score = 160 bits (406), Expect = 2e-39 Identities = 94/254 (37%), Positives = 146/254 (57%), Gaps = 2/254 (0%) Query: 148 LSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWL 207 ++ EDI +D YA+EI+ Y++E E + YM +Q +IT MR ILVDWL Sbjct: 1110 ITPREDIDEDSSDPSFNPMYAKEIFSYMKEREEQFI-LTDYMNRQIEITSDMRAILVDWL 1168 Query: 208 VEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEF 267 VEV +++ ETLYLAV +D +L + KLQL+G A ++A+K+EE P VD+F Sbjct: 1169 VEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDF 1228 Query: 268 VYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAEL 327 VYI DD Y + ++L ME +L VL D+ +P FL +Y R ++T L++Y+ E+ Sbjct: 1229 VYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEM 1288 Query: 328 SLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYL 387 +L E +++ S +AAA+ LA Y +W L ++GYS+SE+ P + +L+K Sbjct: 1289 TLQEYH-YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLT 1347 Query: 388 DIPHRPQQAIREKY 401 + +A+ KY Sbjct: 1348 FSSYDSLKAVYYKY 1361 >gi|16306525 cyclin B3 isoform 1 [Homo sapiens] Length = 291 Score = 119 bits (299), Expect = 4e-27 Identities = 67/188 (35%), Positives = 109/188 (57%), Gaps = 1/188 (0%) Query: 214 YKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDD 273 +++ ETLYLAV +D +L + KLQL+G A ++A+K+EE P VD+FVYI DD Sbjct: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130 Query: 274 TYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEAD 333 Y + ++L ME +L VL D+ +P FL +Y R ++T L++Y+ E++L E Sbjct: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 190 Query: 334 PFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRP 393 +++ S +AAA+ LA Y +W L ++GYS+SE+ P + +L+K + Sbjct: 191 -YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDS 249 Query: 394 QQAIREKY 401 +A+ KY Sbjct: 250 LKAVYYKY 257 >gi|118572588 cyclin F [Homo sapiens] Length = 786 Score = 112 bits (281), Expect = 5e-25 Identities = 91/333 (27%), Positives = 153/333 (45%), Gaps = 20/333 (6%) Query: 84 QEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHF---LLDFNTVSP 140 +E +Q D++ + QG C + +E D LH L D+ Sbjct: 200 EEKQQQAHDLFEEAAHQG----CLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGC 255 Query: 141 MLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMR 200 SL + + LG +V +E +++Q + K Q + + MR Sbjct: 256 WEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVS-----KQQVFSVQKGLNDTMR 310 Query: 201 TILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIY 260 IL+DWLVEV + L+L V +DR+L V R +LQL+G A M++ +++ Sbjct: 311 YILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE 370 Query: 261 PPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL 320 + E V++TD+TY L++M ++ L + VPT + L V +RT++L Sbjct: 371 ILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHL 430 Query: 321 AKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNK-HFWPETLAAFTGYSLSEIVPCL 379 ++ ELSLL Y P+ +AAAA LA T + W L TG+S +++PC+ Sbjct: 431 CSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCV 489 Query: 380 SELHKA--YLDIPHRPQQ----AIREKYKASKY 406 LHK + D P +Q A++++++ +Y Sbjct: 490 LSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRY 522 >gi|17318559 cyclin E1 isoform 1 [Homo sapiens] Length = 410 Score = 105 bits (263), Expect = 6e-23 Identities = 52/142 (36%), Positives = 92/142 (64%), Gaps = 1/142 (0%) Query: 169 EEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFL 228 EE+++ + E + H++++ P + MR IL+DWL+EV E YKL ET YLA +F Sbjct: 114 EEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFF 173 Query: 229 DRFLSCM-SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287 DR+++ +V++ LQL+G +++ +A+K EEIYPP++ +F Y+TD + ++L ME ++ Sbjct: 174 DRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMI 233 Query: 288 LKVLAFDLTVPTTNQFLLQYLR 309 +K L + L+ T +L Y++ Sbjct: 234 MKALKWRLSPLTIVSWLNVYMQ 255 >gi|17318561 cyclin E1 isoform 2 [Homo sapiens] Length = 395 Score = 105 bits (263), Expect = 6e-23 Identities = 52/142 (36%), Positives = 92/142 (64%), Gaps = 1/142 (0%) Query: 169 EEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFL 228 EE+++ + E + H++++ P + MR IL+DWL+EV E YKL ET YLA +F Sbjct: 99 EEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFF 158 Query: 229 DRFLSCM-SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287 DR+++ +V++ LQL+G +++ +A+K EEIYPP++ +F Y+TD + ++L ME ++ Sbjct: 159 DRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMI 218 Query: 288 LKVLAFDLTVPTTNQFLLQYLR 309 +K L + L+ T +L Y++ Sbjct: 219 MKALKWRLSPLTIVSWLNVYMQ 240 >gi|17318565 cyclin E2 [Homo sapiens] Length = 404 Score = 103 bits (256), Expect = 4e-22 Identities = 54/143 (37%), Positives = 88/143 (61%), Gaps = 1/143 (0%) Query: 168 AEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227 ++E++ + + E R+ H+ D+ MR+IL+DWL+EV E Y L ET YLA +F Sbjct: 110 SKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDF 169 Query: 228 LDRF-LSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHL 286 DRF L+ + + LQL+G ++ +ASK EEIY P++ EF Y+TD ++ +L+ME + Sbjct: 170 FDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELI 229 Query: 287 LLKVLAFDLTVPTTNQFLLQYLR 309 +LK L ++L T +L +L+ Sbjct: 230 ILKALKWELCPVTIISWLNLFLQ 252 >gi|4502619 cyclin D3 isoform 2 [Homo sapiens] Length = 292 Score = 101 bits (252), Expect = 1e-21 Identities = 76/226 (33%), Positives = 112/226 (49%), Gaps = 9/226 (3%) Query: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227 + + Q L E R+ P+A Y + Q +I MR +L W++EV EE + E LA+N+ Sbjct: 25 QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNY 84 Query: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287 LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E L+ Sbjct: 85 LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 144 Query: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344 L L +DL + FL L R + + L K A+ L+L D F Y PS+IA Sbjct: 145 LGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIA 204 Query: 345 -----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 385 AA L +++ E LA TG + + C ++ A Sbjct: 205 TGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 250 >gi|153791755 cyclin domain containing [Homo sapiens] Length = 350 Score = 99.8 bits (247), Expect = 4e-21 Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 10/201 (4%) Query: 160 DVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAE 219 D+ +Y + Y + + E P+ + +QP +T R L+ WL+ V ++ L E Sbjct: 94 DLQTFRDYGQSCYAFRKAQESHFHPR-EALARQPQVTAESRCKLLSWLIPVHRQFGLSFE 152 Query: 220 TLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQ 279 +L L VN LDRFL+ V QL+G ++L+A K E++PP V + + + ++++Q Sbjct: 153 SLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQ 212 Query: 280 LLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQ--------GVCVRTENLAKYVAELSLLE 331 L +E ++L L F L PT + FL + + + + LA+ VAELSL + Sbjct: 213 LCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLAD 272 Query: 332 ADPFLKYLPSLIAAAAFCLAN 352 F Y PSL+A LA+ Sbjct: 273 Y-AFTSYSPSLLAICCLALAD 292 >gi|16950655 cyclin D1 [Homo sapiens] Length = 295 Score = 93.2 bits (230), Expect = 4e-19 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%) Query: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227 + + + + +AE P Y K Q ++ MR I+ W++EV EE K E LA+N+ Sbjct: 25 DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84 Query: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287 LDRFLS V + +LQL+G M +ASK +E P ++ TD++ +LL+ME LL Sbjct: 85 LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144 Query: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344 + L ++L T + F+ +L + + + + A+ ++L D F+ PS++A Sbjct: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204 Query: 345 AAAFCLANYTVN 356 A + A +N Sbjct: 205 AGSVVAAVQGLN 216 >gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo sapiens] Length = 307 Score = 91.3 bits (225), Expect = 2e-18 Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 14/204 (6%) Query: 152 EDISSLGTDVINVTEYAEEIYQYL---REAEIRHRPKAHYMKKQPDITEGMRTILVDWLV 208 E +S+LG EYA +I+ + R +R P+A +T MR ++VDWLV Sbjct: 67 EALSALGLQ--GEREYAGDIFAEVMVCRVLPLRALPRA--------VTPEMRALVVDWLV 116 Query: 209 EVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFV 268 +V E L +TLYLAV+ LD +LS V +LQL+G A + +A K EE PE Sbjct: 117 QVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLC 176 Query: 269 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELS 328 ++ D++++ +LL+ E +L L F L P L G + LA Y ELS Sbjct: 177 LLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELS 236 Query: 329 LLEADPFLKYLPSLIAAAAFCLAN 352 LLEA+ + P AAAA LA+ Sbjct: 237 LLEAEA-AGWEPGRRAAAALSLAH 259 >gi|4502617 cyclin D2 [Homo sapiens] Length = 289 Score = 88.2 bits (217), Expect = 1e-17 Identities = 63/189 (33%), Positives = 98/189 (51%), Gaps = 8/189 (4%) Query: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227 + + Q L E R+ P+ Y K Q DI MR ++ W++EV EE K E LA+N+ Sbjct: 24 DRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNY 83 Query: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287 LDRFL+ + + LQL+G M LASK +E P ++ TD++ ++LL+ E ++ Sbjct: 84 LDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVV 143 Query: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344 L L ++L T + F+ LR+ +L + A+ ++L D F Y PS+IA Sbjct: 144 LGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIA 203 Query: 345 ----AAAFC 349 AA C Sbjct: 204 TGSVGAAIC 212 >gi|197276674 cyclin J isoform 1 [Homo sapiens] Length = 383 Score = 77.8 bits (190), Expect = 2e-14 Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%) Query: 166 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 225 + A +I+Q LR E++ Y + P ++ +R D + V + L +LAV Sbjct: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65 Query: 226 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 278 LD F+ + +L LV + +LLASK+EE P++++ + T TK+ Sbjct: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125 Query: 279 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 322 LL ME LLL+ ++L +PT F+ YL +C+ L A Sbjct: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185 Query: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 379 Y E+SL + FL Y PSL+AAA C+A+ + WP L T YS +V C+ Sbjct: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242 Query: 380 SEL 382 L Sbjct: 243 ERL 245 >gi|209862835 cyclin D3 isoform 1 [Homo sapiens] Length = 211 Score = 72.8 bits (177), Expect = 6e-13 Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 8/169 (4%) Query: 225 VNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKME 284 +N+LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60 Query: 285 HLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPS 341 L+L L +DL + FL L R + + L K A+ L+L D F Y PS Sbjct: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120 Query: 342 LIA-----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 385 +IA AA L +++ E LA TG + + C ++ A Sbjct: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 169 >gi|40254889 cyclin J isoform 2 [Homo sapiens] Length = 372 Score = 65.9 bits (159), Expect = 7e-11 Identities = 70/240 (29%), Positives = 107/240 (44%), Gaps = 39/240 (16%) Query: 166 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 225 + A +I+Q LR E++ Y + P ++ +R D + V + L +LAV Sbjct: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65 Query: 226 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 278 LD F+ + +L LV + +LLASK+EE P++++ + T TK+ Sbjct: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125 Query: 279 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL--AKYVA 325 LL ME LLL+ ++L +PT F+ YL +C+ L AKY Sbjct: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKY-- 183 Query: 326 ELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCLSEL 382 AD FL+ SL AAA C+A+ + WP L T YS +V C+ L Sbjct: 184 ------ADYFLEV--SLQVAAA-CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 234 >gi|197276676 cyclin J isoform 3 [Homo sapiens] Length = 371 Score = 65.5 bits (158), Expect = 9e-11 Identities = 63/231 (27%), Positives = 101/231 (43%), Gaps = 22/231 (9%) Query: 166 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 225 + A +I+Q LR E++ Y + P ++ +R D + V + L +LAV Sbjct: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65 Query: 226 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 278 LD F+ + +L LV + +LLASK+EE P++++ + T TK+ Sbjct: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125 Query: 279 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL----AKYVAELSLLEADP 334 LL ME LLL+ ++L +PT F+ YL V +L E + L Sbjct: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSE---AVHETDLHDGWPMICLEKTKLYMAK 182 Query: 335 FLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCLSEL 382 + Y + AA C+A+ + WP L T YS +V C+ L Sbjct: 183 YADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 233 >gi|40805832 cyclin G1 [Homo sapiens] Length = 295 Score = 54.7 bits (130), Expect = 2e-07 Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 17/208 (8%) Query: 160 DVINVTEYAEEIYQY--LREAEIRHRPKA---HYMKKQPD----ITEGMRTILVDWLVEV 210 +V+ T+ + ++Q L E E R +PK ++ D +T +R V L+ + Sbjct: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62 Query: 211 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASK--YEEIYPPEVDEFV 268 + + ET LAVN LDRFLS M V L VG + LA K EE P + + Sbjct: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122 Query: 269 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY--LRRQGVCVRTENLAKYVAE 326 I+ +T L++ME ++L+ + + + T QFL Y L ++ + + N + Sbjct: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182 Query: 327 LSLLEADP----FLKYLPSLIAAAAFCL 350 + L+A F K PS++A + L Sbjct: 183 EAQLKACHCRIIFSKAKPSVLALSIIAL 210 >gi|4757934 cyclin G1 [Homo sapiens] Length = 295 Score = 54.7 bits (130), Expect = 2e-07 Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 17/208 (8%) Query: 160 DVINVTEYAEEIYQY--LREAEIRHRPKA---HYMKKQPD----ITEGMRTILVDWLVEV 210 +V+ T+ + ++Q L E E R +PK ++ D +T +R V L+ + Sbjct: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62 Query: 211 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASK--YEEIYPPEVDEFV 268 + + ET LAVN LDRFLS M V L VG + LA K EE P + + Sbjct: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122 Query: 269 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY--LRRQGVCVRTENLAKYVAE 326 I+ +T L++ME ++L+ + + + T QFL Y L ++ + + N + Sbjct: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182 Query: 327 LSLLEADP----FLKYLPSLIAAAAFCL 350 + L+A F K PS++A + L Sbjct: 183 EAQLKACHCRIIFSKAKPSVLALSIIAL 210 >gi|4757936 cyclin G2 [Homo sapiens] Length = 344 Score = 53.5 bits (127), Expect = 3e-07 Identities = 50/168 (29%), Positives = 75/168 (44%), Gaps = 16/168 (9%) Query: 198 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY- 256 G+R V+ L + + ET LAVN LDRFL+ M V L +G + LLA++ Sbjct: 54 GLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIV 113 Query: 257 -EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCV 315 E+ P + + I+ T + +ME ++ + L ++L T FL Y +C Sbjct: 114 EEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY-HTIILCH 172 Query: 316 RTENLAKYVAELSLLEAD--------PFLKYLPSLIAAAAFCLANYTV 355 +E K + L LEA F K PS++ A CL N V Sbjct: 173 TSER--KEILSLDKLEAQLKACNCRLIFSKAKPSVL---ALCLLNLEV 215 >gi|5802992 cyclin I [Homo sapiens] Length = 377 Score = 46.2 bits (108), Expect = 6e-05 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%) Query: 176 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 235 REA++ + M +++ R ++ WL ++ ++ L ET LA + LDRFL+ + Sbjct: 22 REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80 Query: 236 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 292 L + + LA+K E + + D++ + ++L+ME ++L L Sbjct: 81 KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139 Query: 293 FDLTVPTTNQFL 304 +DL T FL Sbjct: 140 WDLHTATPLDFL 151 >gi|94680985 cyclin J-like [Homo sapiens] Length = 435 Score = 45.8 bits (107), Expect = 7e-05 Identities = 37/133 (27%), Positives = 59/133 (44%), Gaps = 23/133 (17%) Query: 274 TYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYL-------------------RRQGVC 314 T TK++LL E LLL+ +++L +PT FL YL R+ C Sbjct: 169 TLTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKEC 228 Query: 315 VRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVN-KHFWPETLAAFTGYSLS 373 ++ A Y E++ L+ F K+ PS++AAA + + +W L + YSL Sbjct: 229 LK--EYAHYFLEVT-LQDHIFYKFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLE 285 Query: 374 EIVPCLSELHKAY 386 + C+ L Y Sbjct: 286 HLSTCIEILLVVY 298 >gi|89886237 cyclin I family, member 2 [Homo sapiens] Length = 369 Score = 45.1 bits (105), Expect = 1e-04 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 3/117 (2%) Query: 190 KKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAA 249 K Q +I + +++ WL+ + + T LA+ R L + V L + Sbjct: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199 Query: 250 MLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFL 304 + LA+K EE + P+V +F Y+ +LL+ME +L L +DL + T FL Sbjct: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFL 256 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 14/117 (11%) Query: 206 WLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVD 265 ++ +VG L +TL + + RF S + + G + LA K EE D Sbjct: 56 FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD 115 Query: 266 ------------EFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR 310 +F DD K +++ +E +LL+ + FDL V QFLL+Y ++ Sbjct: 116 IIKTARSLLNDVQFGQFGDDP--KEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQ 170 >gi|38176158 cyclin K isoform 2 [Homo sapiens] Length = 354 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 14/117 (11%) Query: 206 WLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVD 265 ++ +VG L +TL + + RF S + + G + LA K EE D Sbjct: 56 FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD 115 Query: 266 ------------EFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR 310 +F DD K +++ +E +LL+ + FDL V QFLL+Y ++ Sbjct: 116 IIKTARSLLNDVQFGQFGDDP--KEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQ 170 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.137 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,367,491 Number of Sequences: 37866 Number of extensions: 732370 Number of successful extensions: 1647 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1584 Number of HSP's gapped (non-prelim): 53 length of query: 421 length of database: 18,247,518 effective HSP length: 105 effective length of query: 316 effective length of database: 14,271,588 effective search space: 4509821808 effective search space used: 4509821808 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.