Guide to the Human Genome
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Search of human proteins with 157739864

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]
         (1302 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]      2589   0.0  
gi|38327034 ubiquitination factor E4B isoform 2 [Homo sapiens]       1820   0.0  
gi|38327029 ubiquitination factor E4A [Homo sapiens]                  277   5e-74
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    60   2e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   3e-08
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             59   4e-08
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         56   2e-07
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    54   1e-06
gi|91982772 mucin 17 [Homo sapiens]                                    54   1e-06
gi|149408144 TOX high mobility group box family member 2 isoform...    53   2e-06
gi|149408141 TOX high mobility group box family member 2 isoform...    53   2e-06
gi|14249636 TOX high mobility group box family member 2 isoform ...    53   2e-06
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    53   2e-06
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          52   5e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    52   5e-06
gi|24430146 nucleoporin 153kDa [Homo sapiens]                          51   6e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   6e-06
gi|91208420 bassoon protein [Homo sapiens]                             51   6e-06
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    51   8e-06
gi|151301154 mucin 6, gastric [Homo sapiens]                           50   1e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             50   1e-05
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                50   2e-05
gi|42476164 POU class 2 homeobox 1 [Homo sapiens]                      49   3e-05
gi|134244285 Notch homolog 3 [Homo sapiens]                            49   3e-05
gi|55953110 retinoblastoma protein-binding zinc finger protein i...    49   4e-05
gi|20336260 retinoblastoma protein-binding zinc finger protein i...    49   4e-05
gi|20336258 retinoblastoma protein-binding zinc finger protein i...    49   4e-05
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              48   5e-05
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       48   7e-05
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...    48   7e-05

>gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]
          Length = 1302

 Score = 2589 bits (6711), Expect = 0.0
 Identities = 1302/1302 (100%), Positives = 1302/1302 (100%)

Query: 1    MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM 60
            MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM
Sbjct: 1    MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM 60

Query: 61   TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV 120
            TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV
Sbjct: 61   TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV 120

Query: 121  DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL 180
            DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL
Sbjct: 121  DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL 180

Query: 181  SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD 240
            SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD
Sbjct: 181  SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD 240

Query: 241  RNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAA 300
            RNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAA
Sbjct: 241  RNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAA 300

Query: 301  SQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSP 360
            SQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSP
Sbjct: 301  SQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSP 360

Query: 361  QAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSDHFTIET 420
            QAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSDHFTIET
Sbjct: 361  QAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSDHFTIET 420

Query: 421  CKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPR 480
            CKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPR
Sbjct: 421  CKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPR 480

Query: 481  SLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLDSDY 540
            SLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLDSDY
Sbjct: 481  SLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLDSDY 540

Query: 541  FKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFFSFSVF 600
            FKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFFSFSVF
Sbjct: 541  FKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFFSFSVF 600

Query: 601  AEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETREAALSY 660
            AEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETREAALSY
Sbjct: 601  AEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETREAALSY 660

Query: 661  MAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHPRCRITL 720
            MAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHPRCRITL
Sbjct: 661  MAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHPRCRITL 720

Query: 721  PNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRL 780
            PNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRL
Sbjct: 721  PNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRL 780

Query: 781  RAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFL 840
            RAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFL
Sbjct: 781  RAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFL 840

Query: 841  RRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFFIVQYSP 900
            RRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFFIVQYSP
Sbjct: 841  RRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFFIVQYSP 900

Query: 901  QALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHP 960
            QALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHP
Sbjct: 901  QALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHP 960

Query: 961  LSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFMEEFNSG 1020
            LSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFMEEFNSG
Sbjct: 961  LSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFMEEFNSG 1020

Query: 1021 KQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDE 1080
            KQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDE
Sbjct: 1021 KQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDE 1080

Query: 1081 RVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVEN 1140
            RVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVEN
Sbjct: 1081 RVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVEN 1140

Query: 1141 PEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIA 1200
            PEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIA
Sbjct: 1141 PEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIA 1200

Query: 1201 IEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILR 1260
            IEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILR
Sbjct: 1201 IEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILR 1260

Query: 1261 HLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH 1302
            HLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH
Sbjct: 1261 HLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH 1302


>gi|38327034 ubiquitination factor E4B isoform 2 [Homo sapiens]
          Length = 1173

 Score = 1820 bits (4714), Expect = 0.0
 Identities = 919/948 (96%), Positives = 920/948 (97%), Gaps = 6/948 (0%)

Query: 358  SSPQAVPASS-SRQRPSSTG--PPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSD 414
            S P A  A S  R    +TG  P   P   S  S   SSL    SLGASGGASNWDSYSD
Sbjct: 229  SQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLS---SLGASGGASNWDSYSD 285

Query: 415  HFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQG 474
            HFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQG
Sbjct: 286  HFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQG 345

Query: 475  SLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKEC 534
            SLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKEC
Sbjct: 346  SLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKEC 405

Query: 535  SLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAF 594
            SLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAF
Sbjct: 406  SLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAF 465

Query: 595  FSFSVFAEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETR 654
            FSFSVFAEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETR
Sbjct: 466  FSFSVFAEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETR 525

Query: 655  EAALSYMAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHP 714
            EAALSYMAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHP
Sbjct: 526  EAALSYMAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHP 585

Query: 715  RCRITLPNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCR 774
            RCRITLPNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCR
Sbjct: 586  RCRITLPNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCR 645

Query: 775  RYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGL 834
            RYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGL
Sbjct: 646  RYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGL 705

Query: 835  LDESFLRRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFF 894
            LDESFLRRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFF
Sbjct: 706  LDESFLRRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFF 765

Query: 895  IVQYSPQALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFE 954
            IVQYSPQALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFE
Sbjct: 766  IVQYSPQALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFE 825

Query: 955  MIENHPLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFM 1014
            MIENHPLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFM
Sbjct: 826  MIENHPLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFM 885

Query: 1015 EEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQS 1074
            EEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQS
Sbjct: 886  EEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQS 945

Query: 1075 QLAQDERVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCR 1134
            QLAQDERVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCR
Sbjct: 946  QLAQDERVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCR 1005

Query: 1135 DLKVENPEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAG 1194
            DLKVENPEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAG
Sbjct: 1006 DLKVENPEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAG 1065

Query: 1195 IKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMD 1254
            IKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMD
Sbjct: 1066 IKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMD 1125

Query: 1255 RSIILRHLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH 1302
            RSIILRHLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH
Sbjct: 1126 RSIILRHLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH 1173



 Score =  527 bits (1357), Expect = e-149
 Identities = 276/285 (96%), Positives = 276/285 (96%), Gaps = 3/285 (1%)

Query: 1   MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM 60
           MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM
Sbjct: 1   MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM 60

Query: 61  TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV 120
           TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV
Sbjct: 61  TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV 120

Query: 121 DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL 180
           DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL
Sbjct: 121 DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL 180

Query: 181 SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD 240
           SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD
Sbjct: 181 SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD 240

Query: 241 RNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSS 285
           RNLLLNTGSNPGTSPMFCSVASFGASSLSSL  S  A   S W S
Sbjct: 241 RNLLLNTGSNPGTSPMFCSVASFGASSLSSLGASGGA---SNWDS 282


>gi|38327029 ubiquitination factor E4A [Homo sapiens]
          Length = 1073

 Score =  277 bits (708), Expect = 5e-74
 Identities = 246/931 (26%), Positives = 434/931 (46%), Gaps = 89/931 (9%)

Query: 423  ETDMLNYLIECFDRVGIEEKKAPKMCSQPAV---SQLLSNIRSQCISHTALVLQGSLTQP 479
            E  +  YL  CF R   E  K P+     AV   +  +SN R+  ++    V Q    Q 
Sbjct: 170  ERHIFCYLYSCFQRAKEEITKVPENLLPFAVQCRNLTVSNTRTVLLTPEIYVDQNIHEQL 229

Query: 480  RSLQQPSFLVPYMLCRNLPYG----FIQELVRTTHQDEEV--FKQIFIPILQGLALAAKE 533
              L   +          + +     F++E++     DEEV  F ++ IP+   L    K+
Sbjct: 230  VDLMLEAIQGAREYMNKIYFEDVTEFLEEVIEALILDEEVRTFPEVMIPVFDILLGRIKD 289

Query: 534  CSLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGA 593
              L        L  L      K          +A + +   +   P  G+  Q+ + LG 
Sbjct: 290  LELCQILLYAYLDILLYFTRQKD---------MAKVFVEYIQPKDPTNGQMYQK-TLLGV 339

Query: 594  FFSFSVFAEDDVKVVEK--YFSGPAITL-ENTRVVSQSLQHYLELGRQELFKILHSIL-L 649
              S S   +    VVE   YF  P+ +  +  +V   ++  ++    ++++++L ++L L
Sbjct: 340  ILSISCLLKTP-GVVENHGYFLNPSRSSPQEIKVQEANIHQFMAQFHEKIYQMLKNLLQL 398

Query: 650  NGETREAALSYMAAVVNANMKKAQMQTDD------RLVSTDGFMLNFLWVLQQLSTKI-- 701
            + ET+   LS++   ++AN  + ++  +       ++ ++D F LN    L +L      
Sbjct: 399  SPETKHCILSWLGNCLHANAGRTKIWANQMPEIFFQMYASDAFFLNLGAALLKLCQPFCK 458

Query: 702  ----KLETVDPTYIFHPRCRITLPNDETRV--NATMEDVNDWLTELYGDQPPFSEPKFPT 755
                +L T +PTY     C +   NDE R   N  M  ++     +    P   EPKFP 
Sbjct: 459  PRSSRLLTFNPTY-----CALKELNDEERKIKNVHMRGLDKETCLI----PAVQEPKFPQ 509

Query: 756  ECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRTVEDLKNNESQWKD-----SPLATRHR 810
                +T +      L     Y+   R   ++ +  ++L   +  W+D     SP A   R
Sbjct: 510  NYNLVTENL----ALTEYTLYLGFHRLHDQMVKINQNLHRLQVAWRDAQQSSSPAADNLR 565

Query: 811  EMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGLLIQLLLRIL---DPAYP-DIT 866
            E       Q ++L+         + +   L+ CLN    +  LL+++    + + P ++T
Sbjct: 566  E-------QFERLMTIYLSTKTAMTEPQMLQNCLNLQVSMAVLLVQLAIGNEGSQPIELT 618

Query: 867  LPLNSDVPKVFAALPEFYVEDVAEFLFFIVQYSPQALYEPCT--QDIVMFLVVMLCNQNY 924
             PL  D     A +PEF+ +++ +FL F+ +++   L       + ++ F+ +   +   
Sbjct: 619  FPL-PDGYSSLAYVPEFFADNLGDFLIFLRRFADDILETSADSLEHVLHFITIFTGSIER 677

Query: 925  IRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHPLS------TKLLVPSLMKFYTDVE 978
            ++NP+L AKL EV+    P +          + +             L  +L+K + D+E
Sbjct: 678  MKNPHLRAKLAEVLEAVMPHLDQTPNPLVSSVFHRKRVFCNFQYAPQLAEALIKVFVDIE 737

Query: 979  HTGATSEFYDKFTIRYHISTIFKSLW---------QNIAHHGTFMEEFNSGKQFVRYINM 1029
             TG   +F  KF  R  +  I + +W         +++A + +   E  +   F+R++N+
Sbjct: 738  FTGDPHQFEQKFNYRRPMYPILRYMWGTDTYRESIKDLADYASKNLEAMNPPLFLRFLNL 797

Query: 1030 LINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDERVSRSYLAL 1089
            L+ND  FLLDE+++ L +I ++Q+  K++ +WD L  + ++ +++ L    +++R +  +
Sbjct: 798  LMNDAIFLLDEAIQYLSKI-KIQQIEKDRGEWDSLTPEARREKEAGLQMFGQLARFHNIM 856

Query: 1090 ATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPK 1149
            + ET+     LT +++  F+ P L  R+ +MLN+ LQ L GPK   LKV++  ++ F+P+
Sbjct: 857  SNETIGTLAFLTSEIKSLFVHPFLAERIISMLNYFLQHLVGPKMGALKVKDFSEFDFKPQ 916

Query: 1150 KLLDQLTDIYLQL-DCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIAIEKFKLLA 1208
            +L+  +  IYL L D   F   +  D RSYS  LF + +  ++K   K    I  F  LA
Sbjct: 917  QLVSDICTIYLNLGDEENFCATVPKDGRSYSPTLFAQTVRVLKKIN-KPGNMIMAFSNLA 975

Query: 1209 EKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTI-MDRSIILRHLLNSPT 1267
            E+++ +     + E  Y+DA DEF DP+M TLM DPV LPS  + +DRS I RHLL+  T
Sbjct: 976  ERIKSLADLQQQEEETYADACDEFLDPIMSTLMCDPVVLPSSRVTVDRSTIARHLLSDQT 1035

Query: 1268 DPFNRQTLTESMLEPVPELKEQIQAWMREKQ 1298
            DPFNR  LT   + P  ELKE+IQ W+ E++
Sbjct: 1036 DPFNRSPLTMDQIRPNTELKEKIQRWLAERK 1066


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 98/442 (22%), Positives = 153/442 (34%), Gaps = 61/442 (13%)

Query: 5   SADEIRRRRLARLAGG---QTSQPTTPLTSPQRENPP--------GPPIAASAPGPSQSL 53
           +A  + R+ LA  AGG    T   + P   P R + P         PP   ++PGP  S 
Sbjct: 49  AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSP 108

Query: 54  GLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSNSL--------------ETQSQS 99
           G       P   P+G  G+   ++ +      + +P  S                T S +
Sbjct: 109 GRASGTTRPG--PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 166

Query: 100 LSRSQSMDIDGVSCEKSMSQVDVDSGIEN-----MEVDENDRREKRSLSDKEPSSGPEVS 154
           ++R        V   +           E          E+   E    + + PS+G  + 
Sbjct: 167 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 226

Query: 155 EEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMST 214
              +  L      +S   R       +  +      PK          G   +    ++ 
Sbjct: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK--------GLQALRPPQVTP 278

Query: 215 QTRDENPFASLTATSQ---PIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSL 271
             +D  P     ++S    P  +A  SP     L T  +P  +P   +  S G+ +L + 
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338

Query: 272 YESSPAPTPSFWSSVPVMGP-SLASPSRAASQLAVPSTPLSPHSAASGTAAGS------- 323
           +   P+P  S  ++ P   P +LA P   A      S PLSP +  S  A  +       
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398

Query: 324 -----QPSSPRYRPYTVTHPWASSGVSILSSSPS--PPALASSPQAVPASSSRQRPSSTG 376
                 PS P   P++   P AS  VS  ++ PS  PP+LA+ P  VP S     P S  
Sbjct: 399 APFSPPPSPPVQAPFS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 455

Query: 377 PPLPPASPSATSRRPSSLRISP 398
              PP +P   +  P  L   P
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPP 477



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 38/120 (31%), Positives = 56/120 (46%), Gaps = 18/120 (15%)

Query: 275 SPAPTPSFWS-----SVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPR 329
           SP P+P   +     + P + PS   PS+A   LA P   + P   AS   + S    P+
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461

Query: 330 YRPYTVTHPWASSGVSILSSSP-SPPALASSP-QAVPASSSRQRPSSTGPPLPPASPSAT 387
             P     P A+  + +    P +PPALA+ P QA+P+      P ++ P   P SPSA+
Sbjct: 462 APP-----PLAAPPLQLAKPPPQAPPALATPPLQALPS------PPASFPGQAPFSPSAS 510



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 53/199 (26%), Positives = 69/199 (34%), Gaps = 31/199 (15%)

Query: 220 NPFASLTATSQPIAAAAR-----SPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYES 274
           +P A+    + P+ AA       SP  +  L     P T     SV+      L+     
Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG---PRLTLALAP 570

Query: 275 SPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYT 334
            P P PS   S  + GP LA  S +A+     STP       SG   G+  S P      
Sbjct: 571 GPPPPPSRSPSSTLSGPDLAGHSSSAT-----STPEELRGYDSGPEGGAAASPPPDAELA 625

Query: 335 VTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPP--------LPPASPSA 386
             HP A       S  P+PP         P       P +TGP              P +
Sbjct: 626 ACHPAA------WSRGPAPPLAFRGAPGAPL----PWPPATGPGSADGLCTIYETEGPES 675

Query: 387 TSRRPSSLRISPSLGASGG 405
            +  P +L   PS G SGG
Sbjct: 676 ATPAPGALDPGPSPGTSGG 694



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 52/155 (33%), Positives = 71/155 (45%), Gaps = 28/155 (18%)

Query: 262 SFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASP-SRAASQLAVP-STPLSPHSAASGT 319
           S  ++S  S  E SPA         P  G  L  P SR+ S  A P S+P     +A GT
Sbjct: 199 SVSSASEHSTTEPSPAARRR-----PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 253

Query: 320 A-AGSQPSSPR------YRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRP 372
             A + PS P+       RP  VT P   +       +P+   L+SSP A P+ S+   P
Sbjct: 254 PRAPAHPSQPKPKGLQALRPPQVTPPRKDA-------APALGPLSSSPLATPSPSAPPSP 306

Query: 373 SSTGP----PLPPASPSATSRRPSSLRISPSLGAS 403
           S+       P PPA+P   S+  +SL  SP+L A+
Sbjct: 307 SAPPSLQTLPSPPATP--PSQATTSLG-SPTLQAT 338



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 50/145 (34%), Positives = 61/145 (42%), Gaps = 29/145 (20%)

Query: 273 ESSPAPTPSFWSSVPV-------MGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQP 325
           ++ P+P  SF    P        M P    P +A   LA P   + P   AS T      
Sbjct: 490 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL----- 544

Query: 326 SSPRYRPYTVTHPWASSGVSI-LSSSPSPPALASSPQAVPASSSRQRPSST--GPPLPPA 382
            +PR RP T     + SG  + L+ +P PP         P S S   PSST  GP L   
Sbjct: 545 QAPR-RPPTPGPDTSVSGPRLTLALAPGPPP--------PPSRS---PSSTLSGPDLAGH 592

Query: 383 SPSATSRRPSSLRISPSLGASGGAS 407
           S SATS  P  LR   S G  GGA+
Sbjct: 593 SSSATS-TPEELRGYDS-GPEGGAA 615



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 38/139 (27%), Positives = 53/139 (38%), Gaps = 24/139 (17%)

Query: 277 APTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVT 336
           AP     S  PV  P  AS +     L      +S   A    A G    +P+       
Sbjct: 94  APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS---AEETVARGKATEAPKRSAL--- 147

Query: 337 HPWASSGVSILSSSPSP----PALASSPQAV--------PASSSRQRPSSTGP--PLPPA 382
               S+G    +S P+P    PA+A   +A         PA S+R RP + GP   +  A
Sbjct: 148 ----SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 203

Query: 383 SPSATSRRPSSLRISPSLG 401
           S  +T+    + R  PS G
Sbjct: 204 SEHSTTEPSPAARRRPSAG 222


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 57/192 (29%), Positives = 81/192 (42%), Gaps = 19/192 (9%)

Query: 223 ASLTAT-SQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPS 281
           +SLT   + P+  A  SP     L T  +P  +P   +  S G+ +L + +   P+P  S
Sbjct: 328 SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387

Query: 282 FWSSVPVMGP-SLASPSRAASQLAVPSTPLSPHSAASGTAAGS------------QPSSP 328
             ++ P   P +LA P   A      S PLSP +  S  A  +             PS P
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447

Query: 329 RYRPYTVTHPWASSGVSILSSSPS--PPALASSPQAVPASSSRQRPSSTGPPLPPASPSA 386
              P++   P AS  VS  ++ PS  PP+LA+ P  VP S     P S     PP +P  
Sbjct: 448 VQAPFS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504

Query: 387 TSRRPSSLRISP 398
            +  P  L   P
Sbjct: 505 LAAPPLQLAKPP 516



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 38/120 (31%), Positives = 56/120 (46%), Gaps = 18/120 (15%)

Query: 275 SPAPTPSFWS-----SVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPR 329
           SP P+P   +     + P + PS   PS+A   LA P   + P   AS   + S    P+
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500

Query: 330 YRPYTVTHPWASSGVSILSSSP-SPPALASSP-QAVPASSSRQRPSSTGPPLPPASPSAT 387
             P     P A+  + +    P +PPALA+ P QA+P+      P ++ P   P SPSA+
Sbjct: 501 APP-----PLAAPPLQLAKPPPQAPPALATPPLQALPS------PPASFPGQAPFSPSAS 549



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 58/158 (36%), Positives = 69/158 (43%), Gaps = 29/158 (18%)

Query: 262 SFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASP-SRAASQLAVP-STPLSPHSAASGT 319
           S  ++S  S  E SPA         P  G  L  P SR+ S  A P S+P     +A GT
Sbjct: 208 SVSSASEHSTTEPSPAARRR-----PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262

Query: 320 A-AGSQPSSPR------YRPYTVTHPW--ASSGVSILSSSP----SPPALASSPQ----- 361
             A + PS P+       RP  VT P   A+  +  LSSSP    SP A   S       
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP 322

Query: 362 AVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPS 399
           A P SSS     +T  PL P SPSA    P SL+  PS
Sbjct: 323 ATPHSSSLTCQLATPLPLAPPSPSA----PPSLQTLPS 356



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 53/199 (26%), Positives = 69/199 (34%), Gaps = 31/199 (15%)

Query: 220 NPFASLTATSQPIAAAAR-----SPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYES 274
           +P A+    + P+ AA       SP  +  L     P T     SV+      L+     
Sbjct: 553 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG---PRLTLALAP 609

Query: 275 SPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYT 334
            P P PS   S  + GP LA  S +A+     STP       SG   G+  S P      
Sbjct: 610 GPPPPPSRSPSSTLSGPDLAGHSSSAT-----STPEELRGYDSGPEGGAAASPPPDAELA 664

Query: 335 VTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPP--------LPPASPSA 386
             HP A       S  P+PP         P       P +TGP              P +
Sbjct: 665 ACHPAA------WSRGPAPPLAFRGAPGAPL----PWPPATGPGSADGLCTIYETEGPES 714

Query: 387 TSRRPSSLRISPSLGASGG 405
            +  P +L   PS G SGG
Sbjct: 715 ATPAPGALDPGPSPGTSGG 733



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 50/145 (34%), Positives = 61/145 (42%), Gaps = 29/145 (20%)

Query: 273 ESSPAPTPSFWSSVPV-------MGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQP 325
           ++ P+P  SF    P        M P    P +A   LA P   + P   AS T      
Sbjct: 529 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL----- 583

Query: 326 SSPRYRPYTVTHPWASSGVSI-LSSSPSPPALASSPQAVPASSSRQRPSST--GPPLPPA 382
            +PR RP T     + SG  + L+ +P PP         P S S   PSST  GP L   
Sbjct: 584 QAPR-RPPTPGPDTSVSGPRLTLALAPGPPP--------PPSRS---PSSTLSGPDLAGH 631

Query: 383 SPSATSRRPSSLRISPSLGASGGAS 407
           S SATS  P  LR   S G  GGA+
Sbjct: 632 SSSATS-TPEELRGYDS-GPEGGAA 654



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 46/189 (24%), Positives = 73/189 (38%), Gaps = 34/189 (17%)

Query: 244 LLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQL 303
           +L      G  P+       G +++    ES+P   P+  +      P+   P+    + 
Sbjct: 46  VLGAAGAVGRKPLAERAGGIGGATIP---ESAPRAGPTRSAGTSSRNPASRPPASGRGER 102

Query: 304 AVPSTPLSPHSAAS-GTAAGSQPSSPRYRP-------YTVTHPWA---------SSGVSI 346
           A P+   SP   +S G A+G+    P  +         TV    A         S+G   
Sbjct: 103 APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 162

Query: 347 LSSSPSP----PALASSPQAV--------PASSSRQRPSSTGP--PLPPASPSATSRRPS 392
            +S P+P    PA+A   +A         PA S+R RP + GP   +  AS  +T+    
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222

Query: 393 SLRISPSLG 401
           + R  PS G
Sbjct: 223 AARRRPSAG 231



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 7/97 (7%)

Query: 292 SLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSP 351
           +L++ +R  +    P TP SP  A    AAG++   PR  P     P        +SS+ 
Sbjct: 155 ALSAGARRDTSGPTPGTP-SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS 213

Query: 352 SPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATS 388
                  SP A      R+RPS+ G    PAS S +S
Sbjct: 214 EHSTTEPSPAA------RRRPSAGGGLQRPASRSLSS 244



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 19/99 (19%)

Query: 306 PSTPLSPHSAASGTAAGSQPSSPRYRPYTVT---HPWASSGVSILSSSPSP--------- 353
           PS  ++  S A+GT  G    +P  RP   T       SS     ++ PSP         
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231

Query: 354 -----PALAS-SPQAVPASS-SRQRPSSTGPPLPPASPS 385
                PA  S S  A P SS +R  PS+ G P  PA PS
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 14/92 (15%)

Query: 14  LARLAGGQTSQPTTPLTSPQRENPP--GPPIAASAPGPSQSLGLNVHNMTPATSPIGASG 71
           L R A    S   TPL+SP R  P   G P A + P   +  GL        T P     
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP----- 288

Query: 72  VAHRSQSSEGVSSLSSS----PSNSLETQSQS 99
              R  ++  +  LSSS    PS S   QSQ+
Sbjct: 289 ---RKDAAPALGPLSSSPLATPSPSAALQSQA 317


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 51/165 (30%), Positives = 70/165 (42%), Gaps = 11/165 (6%)

Query: 245  LNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLA 304
            + +G  PG +    S AS  AS  S  Y  + +PTP    S     P + SP  A S   
Sbjct: 1535 VGSGMTPGAAGFSPSAAS-DASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSY 1593

Query: 305  VPSTPL---------SPHSAA-SGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPP 354
             P++P          +P S + S T+    P+SP Y P +  +   S   S  S S SP 
Sbjct: 1594 SPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPT 1653

Query: 355  ALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPS 399
            + + SP +   S +    S T P   P SPS +   PS    SPS
Sbjct: 1654 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1698



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 51/158 (32%), Positives = 71/158 (44%), Gaps = 5/158 (3%)

Query: 247  TGSNPGTSPMFCSV-ASFGASSLSSLYESSP--APTPSFWSSVPVMGPSLASPSRAASQL 303
            +G +PG SP +     S G+   SS Y  SP  A +PS+  + P   P         S  
Sbjct: 1555 SGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPS 1614

Query: 304  AVPSTP-LSPHSAA-SGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQ 361
              P++P  SP S + S T+    P+SP Y P + ++   S   S  S S SP + + SP 
Sbjct: 1615 YSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1674

Query: 362  AVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPS 399
            +   S +    S T P   P SPS +   PS    SPS
Sbjct: 1675 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1712



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 44/147 (29%), Positives = 67/147 (45%), Gaps = 3/147 (2%)

Query: 253  TSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSP 312
            TSP +   +   + +  S   +SP+ +P+  S  P   PS +  S + S  +   +P SP
Sbjct: 1625 TSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPT-SPSYSPTSPSYSPTSPSYSPTSP 1683

Query: 313  HSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRP 372
              + S T+    P+SP Y P + ++   S   S  S S SP + + SP +   S +    
Sbjct: 1684 --SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1741

Query: 373  SSTGPPLPPASPSATSRRPSSLRISPS 399
            S T P   P SP+ T   PS    SPS
Sbjct: 1742 SPTSPNYSPTSPNYTPTSPSYSPTSPS 1768



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 6/166 (3%)

Query: 253  TSPMFCSVASFGASSLSSLYE-SSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLS 311
            TSP +   +  G +  S  Y  +SP+ +P+  S  P   P+ +  S + S  +   +P S
Sbjct: 1596 TSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPT-SPNYSPTSPSYSPTSPSYSPTS 1654

Query: 312  PHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQR 371
            P  + S T+    P+SP Y P + ++   S   S  S S SP + + SP +   S +   
Sbjct: 1655 P--SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1712

Query: 372  PSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSDHFT 417
             S T P   P SPS +   PS    SPS   S  + N+   S ++T
Sbjct: 1713 YSPTSPSYSPTSPSYSPTSPSYSPTSPSY--SPTSPNYSPTSPNYT 1756



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 43/147 (29%), Positives = 67/147 (45%), Gaps = 3/147 (2%)

Query: 253  TSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSP 312
            TSP +   +   + +  S   +SP+ +P+  S  P   PS +  S + S  +   +P SP
Sbjct: 1632 TSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT-SPSYSPTSPSYSPTSPSYSPTSP 1690

Query: 313  HSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRP 372
              + S T+    P+SP Y P + ++   S   S  S S SP + + SP +   S +    
Sbjct: 1691 --SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNY 1748

Query: 373  SSTGPPLPPASPSATSRRPSSLRISPS 399
            S T P   P SPS +   PS    SP+
Sbjct: 1749 SPTSPNYTPTSPSYSPTSPSYSPTSPN 1775



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 13/166 (7%)

Query: 247  TGSNPGT-SPMFCSVASFGASSLSSLYESSPA-----------PTPSFWSSVPVMGPSLA 294
            T  +PG+  P    + S G +   S   +SPA            +PS+  + P   P+  
Sbjct: 1568 TPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSP 1627

Query: 295  SPSRAASQLAVPSTPLSPHSAA-SGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSP 353
            S S  +   +  S   SP S + S T+    P+SP Y P + ++   S   S  S S SP
Sbjct: 1628 SYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1687

Query: 354  PALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPS 399
             + + SP +   S +    S T P   P SPS +   PS    SPS
Sbjct: 1688 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1733



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 42/151 (27%), Positives = 68/151 (45%), Gaps = 3/151 (1%)

Query: 253  TSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSP 312
            TSP +   +   + +  S   +SP+ +P+  S  P   PS +  S + S  +   +P SP
Sbjct: 1660 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT-SPSYSPTSPSYSPTSPSYSPTSP 1718

Query: 313  HSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRP 372
              + S T+    P+SP Y P + ++   S   S  S + +P + + SP +   S +    
Sbjct: 1719 --SYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNY 1776

Query: 373  SSTGPPLPPASPSATSRRPSSLRISPSLGAS 403
            + T P   P SPS +   PS    SPS   S
Sbjct: 1777 TPTSPNYSPTSPSYSPTSPSYSPTSPSYSPS 1807



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 42/151 (27%), Positives = 68/151 (45%), Gaps = 3/151 (1%)

Query: 253  TSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSP 312
            TSP +   +   + +  S   +SP+ +P+  S  P   PS +  S + S  +   +P SP
Sbjct: 1681 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT-SPSYSPTSPSYSPTSPSYSPTSP 1739

Query: 313  HSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRP 372
              + S T+    P+SP Y P + ++   S   S  S + +P +   SP +   S +    
Sbjct: 1740 --SYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSY 1797

Query: 373  SSTGPPLPPASPSATSRRPSSLRISPSLGAS 403
            S T P   P+SP  T + P+    SPS   S
Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTPSSPSYSPS 1828



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 46/149 (30%), Positives = 68/149 (45%), Gaps = 10/149 (6%)

Query: 253  TSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSP 312
            TSP +   +   + +  S   +SP+ +P+  S  P   PS +  S   S  +   TP SP
Sbjct: 1702 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT-SPSYSPTSPNYSPTSPNYTPTSP 1760

Query: 313  HSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRP 372
              + S T+    P+SP Y P +  +   S   S  S S SP + + SP     SS R  P
Sbjct: 1761 --SYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSP-----SSPRYTP 1813

Query: 373  SST--GPPLPPASPSATSRRPSSLRISPS 399
             S    P  P  SPS+ S  P+S + +P+
Sbjct: 1814 QSPTYTPSSPSYSPSSPSYSPTSPKYTPT 1842



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 47/153 (30%), Positives = 72/153 (47%), Gaps = 11/153 (7%)

Query: 253  TSPMFCSVASFGASSLSSLYESSP--APT-PSFWSSVPVMGPSLASPSRAASQLAVPSTP 309
            TSP +   +   + +  +   +SP   PT PS+  + P   P+  + +  +   +  S  
Sbjct: 1730 TSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPS 1789

Query: 310  LSPHSAA-SGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSS 368
             SP S + S T+    PSSPRY P + T+  +S   S  S S SP    +SP+  P S S
Sbjct: 1790 YSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSP----TSPKYTPTSPS 1845

Query: 369  RQRPSST--GPPLPPASPSATSRRPSSLRISPS 399
               PSS    P  P  SP++    P+S + SP+
Sbjct: 1846 -YSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPT 1877



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 4/151 (2%)

Query: 253  TSPMFCSVASFGASSLSSLYESSPA---PTPSFWSSVPVMGPSLASPSRAASQLAVPSTP 309
            TSP +   +        +   SSP+    +PS+  + P   P+  S S ++ +    S  
Sbjct: 1800 TSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPK 1859

Query: 310  LSPHSAA-SGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSS 368
             SP S   S T+    P+SP Y P T  +   S   S  S   +P +   SP +   S +
Sbjct: 1860 YSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPT 1919

Query: 369  RQRPSSTGPPLPPASPSATSRRPSSLRISPS 399
              + S T P   P SP  ++  P+S   SP+
Sbjct: 1920 SPKYSPTSPTYSPTSPKGSTYSPTSPGYSPT 1950



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 47/153 (30%), Positives = 61/153 (39%), Gaps = 12/153 (7%)

Query: 254  SPMFCSVASFGASSLSSLYESSPAPTP---SFWSSVPVMGPSLASPSRAASQLAVPSTPL 310
            SP +   +   + S  S   +SP  TP   S+  S P   P+    S  + + +  S   
Sbjct: 1815 SPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKY 1874

Query: 311  SPHSAA-SGTAAGSQPSSPRYRP----YTVTHPWASSGVSILSSSPSPPALASSPQAVPA 365
            SP S   S T     P+SP Y P    YT T P   S  S   S  SP    +SP   P 
Sbjct: 1875 SPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSP-KYSPTSPTYSPTSPKYSPTSPTYSPT 1933

Query: 366  SSSRQRPSSTGPPLPPASPSATSRRPSSLRISP 398
            S      S T P   P SP+ +   P+   ISP
Sbjct: 1934 SPKGSTYSPTSPGYSPTSPTYSLTSPA---ISP 1963



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 7/155 (4%)

Query: 253  TSPMFCSVASFGASSLSSLYESSPA--PT-PSFWSSVPVMGPSLASPSRAASQLAVPSTP 309
            +SP +   +     S  S   SSP+  PT P +  + P   PS    +  + + +  S  
Sbjct: 1807 SSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPK 1866

Query: 310  LSPHSAA-SGTAAGSQPSSPRYRPYTVTHPWASSGVSILS---SSPSPPALASSPQAVPA 365
             SP S   S T+    P++P+Y P + T+   S   +  S   S  SP    +SP+  P 
Sbjct: 1867 YSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPT 1926

Query: 366  SSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSL 400
            S +    S  G    P SP  +   P+    SP++
Sbjct: 1927 SPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAI 1961



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 23/140 (16%)

Query: 278  PTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGT---AAGSQPS-------- 326
            PT  F+ S P     ++      +Q A P+      S  SG    AAG  PS        
Sbjct: 1498 PTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGF 1557

Query: 327  SPRYRPYTVTHPWASSGVSILSSSPSPPAL-----ASSPQAVPASSSRQRPSSTG--PPL 379
            SP Y P      W+ +  S  S  PS P +     A SP   P S + +  S  G  P  
Sbjct: 1558 SPGYSP-----AWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQS 1612

Query: 380  PPASPSATSRRPSSLRISPS 399
            P  SP++ S  P+S   SP+
Sbjct: 1613 PSYSPTSPSYSPTSPSYSPT 1632


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 59/201 (29%), Positives = 91/201 (45%), Gaps = 27/201 (13%)

Query: 224  SLTATSQPIAAAARSPDRNLLLNTGSN--PG---TSPMFCSVASFGASSLSSLYESSPAP 278
            +L   + P  +++++P   LLL   S+  PG   T    CS     AS+L+S + S+P P
Sbjct: 1506 TLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNP 1565

Query: 279  TPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHP 338
             P+          SL +P+ +ASQ    +TPL+P  AA  TA  +   +P   P  V  P
Sbjct: 1566 APA--------QASLLAPASSASQAL--ATPLAP-MAAPQTAILAPSPAPPLAPLPVLAP 1614

Query: 339  WASSGVSILSSSPSPPALA---------SSPQAVPASSSRQRPSSTGP--PLPPASPSAT 387
               +   + SS    P +A         +S   VPA +    PSST    P P  SP  +
Sbjct: 1615 SPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPS 1674

Query: 388  SRRPSSLRISPSLGASGGASN 408
                 +L ++P+L  + G S+
Sbjct: 1675 PASTQTLALAPALAPTLGGSS 1695



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 47/181 (25%), Positives = 73/181 (40%), Gaps = 24/181 (13%)

Query: 221  PFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCS------VASFGASSLSSLYES 274
            P A + A    I A + +P    L     +PG +P+  S      V +  ++  +SL  +
Sbjct: 1586 PLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASA 1645

Query: 275  SPAPTPSFWSSVPVMGPSLAS-------PSRAASQLAVPSTPLSPHSAASGTAAGSQPSS 327
            SP P P+     PV+ PS          PS   S  +  +  L+P  A + T  GS PS 
Sbjct: 1646 SPVPAPT-----PVLAPSSTQTMLPAPVPSPLPSPASTQTLALAP--ALAPTLGGSSPSQ 1698

Query: 328  P-RYRPYTVTHPWASSGVSILSSS---PSPPALASSPQAVPASSSRQRPSSTGPPLPPAS 383
                       P+ +  +S+  +S   P+P    S     P   ++    +  PPL PAS
Sbjct: 1699 TLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPAS 1758

Query: 384  P 384
            P
Sbjct: 1759 P 1759



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 55/203 (27%), Positives = 85/203 (41%), Gaps = 15/203 (7%)

Query: 218  DENPFASLTAT--SQPIAAAARSPDRNLLLNTGSNPGTSPMFC--SVASFGASSLSSLYE 273
            + +P AS  ++  S P++++        L    S P T P+    +V++ G + L+S+  
Sbjct: 1419 NSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTP 1478

Query: 274  SSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPY 333
               AP        P + PS ASPS +A  L + + P    S   G      P+S      
Sbjct: 1479 PL-APVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGL 1537

Query: 334  TVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTG------PPLPPASPSAT 387
              T   A S V + +S+ + P   S+P   PA +S   P+S+       P  P A+P   
Sbjct: 1538 NSTVAPACSPVLVPASALASP-FPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTA 1596

Query: 388  SRRPS---SLRISPSLGASGGAS 407
               PS    L   P L  S GA+
Sbjct: 1597 ILAPSPAPPLAPLPVLAPSPGAA 1619



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 96/402 (23%), Positives = 148/402 (36%), Gaps = 79/402 (19%)

Query: 22   TSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGAS---GVAHRSQS 78
            TS+P TP  S  +  PP P   + AP P  S  L      P T P G +     A  + +
Sbjct: 1096 TSRPPTPTLS-LKPTPPAPVRLSPAPPPGSSSLLK-----PLTVPPGYTFPPAAATTTST 1149

Query: 79   SEGVSSLSSSPSNSLETQSQSLS-----RSQSMDIDGVSCEKSMSQVDVDSGIENMEVDE 133
            +   ++ ++ P+ +   Q   LS     R  S ++  +    S++Q  V +   +  +  
Sbjct: 1150 TTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTF 1209

Query: 134  NDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFK--QNP 191
              +  K +L+  +      V + + LQ              R+V+ L S   Q      P
Sbjct: 1210 QIQGNKLTLTGAQVRQ-LAVGQPRPLQ--------------RNVVHLVSAGGQHHLISQP 1254

Query: 192  KEV--FSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGS 249
              V          G   + VL  ST +    P    T  S P+AA    P   ++ NTG 
Sbjct: 1255 AHVALIQAVAPTPGPTPVSVLPSSTPSTTPAP----TGLSLPLAANQVPP--TMVNNTGV 1308

Query: 250  NPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTP 309
                  +   V       L+ +   +PAP P       V+ P    P+    +L  P+  
Sbjct: 1309 ------VKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPR---PTLTPGRLPTPTL- 1358

Query: 310  LSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPAS--- 366
                    GTA    P+    RP              L  SPSP   AS+P A P +   
Sbjct: 1359 --------GTARAPMPTPTLVRPLLK-----------LVHSPSPEVSASAPGAAPLTISS 1399

Query: 367  -----SSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGAS 403
                 SS   P+S+  P+P +SP A+   P S  +S  L +S
Sbjct: 1400 PLHVPSSLPGPASSPMPIPNSSPLAS---PVSSTVSVPLSSS 1438



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 39/124 (31%), Positives = 52/124 (41%), Gaps = 18/124 (14%)

Query: 273  ESSPAPTP-----SFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSS 327
            + +P P P     S   S    GP L   SR    + +P  PL P+S   G+     PS 
Sbjct: 1035 QPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLP--PLQPNS---GSLPQVLPS- 1088

Query: 328  PRYRPYTVTHPWASSGVSILSSSPSPPA-LASSPQAVPASSSRQRPSSTGP--PLPPASP 384
                P  V    +      LS  P+PPA +  SP   P SSS  +P +  P    PPA+ 
Sbjct: 1089 ----PLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAA 1144

Query: 385  SATS 388
            + TS
Sbjct: 1145 TTTS 1148



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 23/169 (13%)

Query: 230  QPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVM 289
            +P+     SP   +   + S PG +P+  S      SSL     SSP P P+       +
Sbjct: 1372 RPLLKLVHSPSPEV---SASAPGAAPLTISSPLHVPSSLPGP-ASSPMPIPNSSPLASPV 1427

Query: 290  GPSLASPSRAASQLAVPSTPLSPHSA-------ASGTAAGSQPSSPRYRPYTVTHPWASS 342
              +++ P  ++  ++VP+T  +P SA       A  T + S P+       +VT P A  
Sbjct: 1428 SSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLT----SVTPPLA-- 1481

Query: 343  GVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRP 391
               ++ ++P PP+LA S  A P++S+     +T P L   S S T   P
Sbjct: 1482 --PVVPAAPGPPSLAPS-GASPSASALTLGLATAPSL---SSSQTPGHP 1524



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 78/355 (21%), Positives = 125/355 (35%), Gaps = 46/355 (12%)

Query: 86   SSSPSNSLETQSQSLSRSQSMDIDGVSCE-------KSMSQVDVDSGIENMEVDEND--- 135
            SSS  ++ E + ++++  Q+  ++   C        ++ +Q   +   E  E +END   
Sbjct: 2219 SSSVPSAPEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEFNENDGFP 2278

Query: 136  ----RREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNP 191
                    R  ++ E  S  E      ++ +  I R + K  +  +  +S    + KQ  
Sbjct: 2279 AGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSR--EELKQAE 2336

Query: 192  KEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNP 251
            ++V +  KDL  Q   EV  +  Q  +E P A   ++        R   R+        P
Sbjct: 2337 EQVEAARKDL-DQAKEEVFRLP-QEEEEGPGAGDESSCGTGGGTHR---RSKKAKAPERP 2391

Query: 252  GTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLS 311
            GT      V+     + +    ++  P  S   +     P   SP+R       P    +
Sbjct: 2392 GTR-----VSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPT 2446

Query: 312  PHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSP--------PALASSPQAV 363
            P SA +   A          P +  +P     V IL S P P        PA    P   
Sbjct: 2447 PASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACT 2506

Query: 364  PASSSRQRPSST-----------GPPLPPASPSATSRRPSSLRISPSLGASGGAS 407
            P  +    P+ T           GPP  P S S T+  P  LR    L A   AS
Sbjct: 2507 PPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTN-LPLGLRPEAELCAQALAS 2560



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 1/103 (0%)

Query: 293  LASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWAS-SGVSILSSSP 351
            L  P  AAS   +     +  ++   T A +  SSP      VT   A+ S  S  +SSP
Sbjct: 2652 LELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSP 2711

Query: 352  SPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSL 394
              P+ A  P+   ++    R   TG P  P  P    + P  L
Sbjct: 2712 EGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRL 2754


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 490

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 61/192 (31%), Positives = 77/192 (40%), Gaps = 19/192 (9%)

Query: 211 MMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSS 270
           ++S Q    +P   L +    + +  R     LL    S P   P   S    G  SL S
Sbjct: 78  LVSPQYSPVSPHCPLVSPHYSLVSPHRPLVSPLLSGVPSPPSDVPSLLS----GVPSLPS 133

Query: 271 LYESSPAPTPSFWSSVPVMGPSLASPSR--AASQLAVPSTPLSPHSAASGTAAGSQPSSP 328
              S P+  PS  S VP +   + SP     +    VPS P    S  SG    S PS  
Sbjct: 134 DVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVP--SPPSDV 191

Query: 329 RYRPYTVTHPWASSGVSILSSSPSPPA-------LASSPQAVPASSSRQRPSSTGPPLPP 381
              P  V  P   S V +LS  PSPP+       + S P  VP+  S   PS +G P PP
Sbjct: 192 PSPPSDVPSP--PSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPS-DVPSLSGVPSPP 248

Query: 382 AS-PSATSRRPS 392
           +  PS  S  PS
Sbjct: 249 SDVPSLLSGVPS 260



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 56/181 (30%), Positives = 72/181 (39%), Gaps = 21/181 (11%)

Query: 231 PIAAAARSP--DRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPV 288
           P+ +   SP  D  LL +  S P   P   S       SLS +  S P+  PS  S VP 
Sbjct: 206 PLLSDVPSPPSDVPLLSDVPSPPSDVPSLPS----DVPSLSGV-PSPPSDVPSLLSGVPS 260

Query: 289 MGPSLASPSRAASQLA-VPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTH--------PW 339
               ++ PS   S L+ VPS P    S  SG      PS P   P  ++         P 
Sbjct: 261 PPSDISPPSDVPSLLSDVPSLPSDVPSLLSGV-----PSPPSDVPSLLSDVPSPPSDVPS 315

Query: 340 ASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPS 399
             S + +LS  PSPP+   SP +   S     P  +G P P +     S  PS     PS
Sbjct: 316 PPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSGVPSPLSDVPLLSGVPSPPSDVPS 375

Query: 400 L 400
           L
Sbjct: 376 L 376



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 45/135 (33%), Positives = 54/135 (40%), Gaps = 8/135 (5%)

Query: 266 SSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQP 325
           S L S   S P+  PS  S VP +   ++SP        VPS      S  SG    S P
Sbjct: 108 SPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSD-----VPSLLSDVPSLLSGVP--SPP 160

Query: 326 SSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPS 385
           S     P  V  P  S   S+LS  PSPP+   SP +   S     P  +  P PP+   
Sbjct: 161 SDVPSPPSDVPSP-PSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVP 219

Query: 386 ATSRRPSSLRISPSL 400
             S  PS     PSL
Sbjct: 220 LLSDVPSPPSDVPSL 234



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 49/182 (26%), Positives = 65/182 (35%), Gaps = 25/182 (13%)

Query: 229 SQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAP---TPSFWSS 285
           S P   +  S   +LL +  S P   P   S      S + SL    P+P    PS  S 
Sbjct: 260 SPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSD 319

Query: 286 VPVMGPSLASPSRAASQLA-VPSTPLS-------PHSAASGTAAGSQPSSPRYRP----- 332
           +P++    + PS   S  + VPS P         P   +        PS P   P     
Sbjct: 320 IPLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSGVPSPLSDVPLLSGVPSPPSDVPSLLMS 379

Query: 333 --------YTVTHPWASSGVSILSSSPSP-PALASSPQAVPASSSRQRPSSTGPPLPPAS 383
                   Y++  P      S+LS  PS    + SSP  VP+  S     S  P LP   
Sbjct: 380 PHRLLMSHYSLVSPHRLDVPSLLSDVPSLLSGVPSSPSGVPSLPSGVPILSGVPSLPSGV 439

Query: 384 PS 385
           PS
Sbjct: 440 PS 441



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 45/126 (35%), Positives = 50/126 (39%), Gaps = 31/126 (24%)

Query: 249 SNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVP--VMGP--------SLASPSR 298
           S P   P+   V S     LS +   S  P+P   S VP  +M P        SL SP R
Sbjct: 342 SPPSDVPLLSGVPS----PLSDVPLLSGVPSPP--SDVPSLLMSPHRLLMSHYSLVSPHR 395

Query: 299 AASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALAS 358
               L VPS      S  SG      PSSP   P         SGV ILS  PS P+   
Sbjct: 396 ----LDVPSLLSDVPSLLSGV-----PSSPSGVPSL------PSGVPILSGVPSLPSGVP 440

Query: 359 SPQAVP 364
           SP  VP
Sbjct: 441 SPSGVP 446


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 47/394 (11%)

Query: 23   SQPTTPLTS-PQRENPPGPPIAAS-APGPSQSLGLNVHNMTPATSPIGASGVAHR-SQSS 79
            S+ +TPLTS P    P   P A++ +  P  S    V +   ++SP  A G +   S  S
Sbjct: 3042 SEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYS 3101

Query: 80   EGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREK 139
            EG + L+  P ++    S ++S              ++S   VD+        E      
Sbjct: 3102 EGSTPLTGVPVSTTPVTSSAIS--------------TLSTTPVDTSTPVTTSTEAHSSPT 3147

Query: 140  RSLSDKEPSSGP-EVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDF 198
             S     P+S P E S       V  +  VS +D        S+LSA        V +  
Sbjct: 3148 TSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSED--------STLSATPVDTSTPVTTS- 3198

Query: 199  KDLIGQILMEVLMMSTQTRDEN--PFASLTATSQPIAAAARS------PDRNLLLNTGSN 250
             +       E   + T T  E   P  S+  ++ P+A++  S       D N  L T + 
Sbjct: 3199 TEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTE 3258

Query: 251  PGTSP-------MFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQL 303
              +SP       M  S  S G++ L+S+  S+     S  S++       ++P    SQ 
Sbjct: 3259 ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQA 3318

Query: 304  AVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAV 363
            +  S+P      +  T+  S+ S+P       T P  SS  S LS++P      S+P   
Sbjct: 3319 S--SSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVD---TSTPVTT 3373

Query: 364  PASSSRQRPSSTGPPLPPASPSATSRRPSSLRIS 397
               +S    ++ G  +P +SPS  +   +S+ +S
Sbjct: 3374 STEASLSPTTAEGTSIPTSSPSEGTTPLASMPVS 3407



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 107/484 (22%), Positives = 174/484 (35%), Gaps = 129/484 (26%)

Query: 22  TSQPTTP------LTSPQRENPPGP-PIAASAPGPS----QSLGLNVHNMTPATSPIGAS 70
           TS PTTP      +++P  E+        ++AP PS     SL   V   TP T+   AS
Sbjct: 136 TSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQAS 195

Query: 71  G--------VAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDV 122
                       +S +SEG + L+S P+++++  S           + ++   +  ++  
Sbjct: 196 SSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASS----------EAITLLTTPVEIST 245

Query: 123 DSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFR----VSWKDRDRDVI 178
              I           E  SLS+  PS G        L ++  +      +S      ++ 
Sbjct: 246 PVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIP 305

Query: 179 FLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARS 238
            ++S  A       E  S             +  ST T    P  S  A++ P+A +  S
Sbjct: 306 VITSTEASSSPTTAEGTS-------------IPTSTYTEGSTPLTSTPASTMPVATSEMS 352

Query: 239 P------DRNLLLNTGSNPGTSP-------MFCSVASFGASSLSSL-------------- 271
                  D + L+ T + P + P       M  S  S G++ L+++              
Sbjct: 353 TLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEAST 412

Query: 272 ---------------YESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAA 316
                           E+S +PT +  +S+    PS    S   + + V +TP++   A+
Sbjct: 413 TSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPS--EGSTPLTSMPVSTTPVASSEAS 470

Query: 317 S--------------GTAAGSQP----------------SSPRYRPYTVTHPWASSGVSI 346
           +               T A S P                S+P       T P ASS  S 
Sbjct: 471 NLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAST 530

Query: 347 LSSSP---SPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGAS 403
           LS++P   S P   SS     ASSS   P  T   +P ++PS  S   +++ +S  L  S
Sbjct: 531 LSTTPVDTSTPVTTSS----EASSSSTTPEGTS--IPTSTPSEGSTPLTNMPVSTRLVVS 584

Query: 404 GGAS 407
             AS
Sbjct: 585 SEAS 588



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 101/419 (24%), Positives = 158/419 (37%), Gaps = 42/419 (10%)

Query: 4    LSADEIRRRRLARLAGGQTSQPTT------PLTSPQRENPPGPPIAASAPGPSQSLGLNV 57
            LS   +  R L   + G +S PTT      P ++P   + P   I  S    + S    +
Sbjct: 2653 LSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTL 2712

Query: 58   HNMTPATS-PIGASGVAHRSQSS-EGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEK 115
                  TS P+  S  A  S ++ EG S   S+PS+     S  L+      +   S E 
Sbjct: 2713 STTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDG----STPLTSILVSTLPVASSEA 2768

Query: 116  S-MSQVDVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRD 174
            S +S   VD+ I      E       +     P+S P  +      +      V+  +  
Sbjct: 2769 STVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEA- 2827

Query: 175  RDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILME--VLMMSTQTRDENPFASLTATSQPI 232
                   +LS         V +  K        E  V+ +ST +       S+  ++ P+
Sbjct: 2828 ------GTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPV 2881

Query: 233  AAAARSP------DRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSV 286
            A++  S       D ++ + T +   +SP      S   S+ S   E S   T    S+V
Sbjct: 2882 ASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPS---EVSTPLTSILVSTV 2938

Query: 287  PVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAG-SQPSSP---RYRPYTV----THP 338
            PV G   ++ S        P T  +  S++  TA G S P S    R  P T     T P
Sbjct: 2939 PVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMP 2998

Query: 339  WASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRIS 397
             ASS  S LS +   PA  S+P      +S    ++ G  +P ++PS  S   +S+ +S
Sbjct: 2999 VASSEASTLSRT---PADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVS 3054



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 101/419 (24%), Positives = 157/419 (37%), Gaps = 82/419 (19%)

Query: 22   TSQP--TTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATS-PIGASGVA-HRSQ 77
            TS P  TTP+ S +       P+  S P         V   T ATS P  A G +   S 
Sbjct: 927  TSMPDSTTPVVSSEARTLSATPVDTSTP---------VTTSTEATSSPTTAEGTSIPTST 977

Query: 78   SSEGVSSLSSSP-SNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDR 136
             SEG + L+S+P S++L   S++                ++S   VDS        E   
Sbjct: 978  PSEGTTPLTSTPVSHTLVANSEA---------------STLSTTPVDSNTPLTTSTEASS 1022

Query: 137  REKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFS 196
                +     P+S P        ++      V+  +        S+LS         V +
Sbjct: 1023 PPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSET-------STLSTTPADTSTPVTT 1075

Query: 197  DFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPM 256
              +        +   M T T  E    S   TS P++       R ++ +  S   T+P+
Sbjct: 1076 YSQASSSSTTADGTSMPTSTYSEG---STPLTSVPVST------RLVVSSEASTLSTTPV 1126

Query: 257  FCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPS-----LAS---------------- 295
              S+       +++  E+S +PT +  +S+P   PS     LAS                
Sbjct: 1127 DTSIP------VTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTL 1180

Query: 296  ---PSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYT---VTH-PWASSGVSILS 348
               P  + +Q+A  +   SP   A  T+  +     R  P T   V H P ASS  S LS
Sbjct: 1181 STTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLS 1240

Query: 349  SSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGAS 407
            +SP      S+P    A +S    ++ G  LP ++ S  S   +S+ +S +L  S  AS
Sbjct: 1241 TSPVD---TSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEAS 1296



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 97/436 (22%), Positives = 174/436 (39%), Gaps = 79/436 (18%)

Query: 23   SQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPA--TSPIGASGVAHRSQSSE 80
            S+ +T  T+P   N P     A +  P+ + G ++   TP+  ++ + +  V+  + +S 
Sbjct: 1470 SEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASS 1529

Query: 81   GVSSLSSSPS-NSLETQSQSLSRSQSMDIDGVSCEKS----------------------- 116
             ++SLS++P+  S    + S + S     DG S + S                       
Sbjct: 1530 EINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSE 1589

Query: 117  ---MSQVDVDSGIE---NMEVDENDRREKRSLSDKEPSSGP------EVSEEQALQLVCK 164
               +S   +DS  +   + E   +   E  S++   PS G        VS          
Sbjct: 1590 ANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEAS 1649

Query: 165  IFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFAS 224
                +  D +  VI  + +S+     P E  S             +  ST T    P  S
Sbjct: 1650 TLSTTPVDSNSPVITSTEVSS--SPTPAEGTS-------------MPTSTYTEGRTPLTS 1694

Query: 225  LTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLS---SLYESSPAPTPS 281
            +T  + P+A++A S      L+T     ++P+  S  +  + + S   S+  S+P+   +
Sbjct: 1695 ITVRTTPVASSAIS-----TLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTT 1749

Query: 282  FWSSVPVMGPSLASPSRAASQLAVP---STPL-------SPHSAASGTAAGSQPSSPRYR 331
              +S+PV    + S S A++  A P   STP+       S  + A GT+  +   S    
Sbjct: 1750 PLTSIPVSTTPVLS-SEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMT 1808

Query: 332  PYT---VTHPW-ASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSAT 387
            P T   V+H   A+S  S LS++P     ++SP     + S     + G  +  ++PS  
Sbjct: 1809 PLTSTPVSHTLVANSEASTLSTTPVD---SNSPVVTSTAVSSSPTPAEGTSIATSTPSEG 1865

Query: 388  SRRPSSLRISPSLGAS 403
            S   +S+ +S +  AS
Sbjct: 1866 STALTSIPVSTTTVAS 1881



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 87/398 (21%), Positives = 149/398 (37%), Gaps = 51/398 (12%)

Query: 26   TTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVA-HRSQSSEGVSS 84
            TTP+ S +       P+  S PG + +           +SP  A G++   S  SEG + 
Sbjct: 1405 TTPVVSSEASTLSATPVDTSTPGTTSA--------EATSSPTTAEGISIPTSTPSEGKTP 1456

Query: 85   LSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREKRSLSD 144
            L S P ++    +   S   +  +D      S S V   + + +         E  S++ 
Sbjct: 1457 LKSIPVSNTPVANSEASTLSTTPVD------SNSPVVTSTAVSSSPTPA----EGTSIAI 1506

Query: 145  KEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQ 204
              PS G       AL  +     VS        I   S +      P   +S        
Sbjct: 1507 STPSEG-----STALTSI----PVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTT 1557

Query: 205  ILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFG 264
                 +  ST +    P  SL  ++  +     S + N L  T  +  T     + AS  
Sbjct: 1558 ADGTSMQTSTYSEGSTPLTSLPVSTMLVV----SSEANTLSTTPIDSKTQVTASTEASSS 1613

Query: 265  ASSL-SSLYESSPAPTPSFWSSVPVMGPSLASP-------------SRAASQLAVPSTPL 310
             ++  SS+  S+P+      +S+PV    +ASP             S   +   V S+P 
Sbjct: 1614 TTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPT 1673

Query: 311  SPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQ 370
                 +  T+  ++  +P       T P ASS +S LS++P    + +S     ++ +R 
Sbjct: 1674 PAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTP----VDNSTPVTTSTEARS 1729

Query: 371  RP-SSTGPPLPPASPSATSRRPSSLRISPSLGASGGAS 407
             P +S G  +P ++PS  +   +S+ +S +   S  AS
Sbjct: 1730 SPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEAS 1767



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 93/407 (22%), Positives = 152/407 (37%), Gaps = 60/407 (14%)

Query: 23   SQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPAT-------SPIGASG-VAH 74
            S+ +TPLTS    + P   +A+S  G   +    V   TP T       SP  A G V  
Sbjct: 2806 SETSTPLTSMPVNHTP---VASSEAGTLSTTP--VDTSTPVTTSTKASSSPTTAEGIVVP 2860

Query: 75   RSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDEN 134
             S +SEG + L+S P ++    S   S              ++S   VD+ I      E 
Sbjct: 2861 ISTASEGSTLLTSIPVSTTPVASSEAS--------------TLSTTPVDTSIPVTTSTEG 2906

Query: 135  DRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEV 194
                  +     P S P         ++     V+  +        S+LS         V
Sbjct: 2907 SSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEA-------STLSTTPVDTRTPV 2959

Query: 195  FSDFKDLIGQILMEVLMMSTQTRDEN--PFASLTATSQPIAAA-----ARSP-DRNLLLN 246
             +  +        E   M   T  E   P  S++ ++ P+A++     +R+P D +  + 
Sbjct: 2960 TTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVT 3019

Query: 247  TGSNPGTSPMFC-------SVASFGASSLSSLYESSPA---PTPSFWSSVPVMGPSLASP 296
            T +   +SP          S  S G++ L+S+  S+     P  S  S+ PV      S 
Sbjct: 3020 TSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPV-----DSN 3074

Query: 297  SRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPAL 356
            S   +   V S+P      +   +  S+ S+P       T P  SS +S LS++P     
Sbjct: 3075 SPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVD--- 3131

Query: 357  ASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGAS 403
             S+P      +     +S G  +P ++PS  S   + + +S  L  S
Sbjct: 3132 TSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVS 3178



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 85/402 (21%), Positives = 152/402 (37%), Gaps = 70/402 (17%)

Query: 22   TSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPA--TSPIGASGVAHRSQSS 79
            +S+ +   T+P   N P      ++  P  + G ++   TP+  ++P+ +  V+  + +S
Sbjct: 3236 SSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVAS 3295

Query: 80   EGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREK 139
               S+LS++P+   +T +   + SQ+     ++   SM       G              
Sbjct: 3296 SETSTLSTTPA---DTSTPVTTYSQASSSPPIADGTSMPTSTYSEG-------------S 3339

Query: 140  RSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFK 199
              L++   S+ P VS E +         +S    D      +S  A       E  S   
Sbjct: 3340 TPLTNMSFSTTPVVSSEAST--------LSTTPVDTSTPVTTSTEASLSPTTAEGTS--- 3388

Query: 200  DLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAA-----ARSP-DRNLLLNTGSNPGT 253
                      +  S+ +    P AS+  ++ P+ ++     + +P D N L+ T +   +
Sbjct: 3389 ----------IPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASS 3438

Query: 254  SPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPH 313
            SP      S   S+ S   E S   +    S+ PV     ++ S      + P T  SP 
Sbjct: 3439 SPTIAEGTSLPTSTTS---EGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPT 3495

Query: 314  SAASGTA--------AGSQPSSPRYRPYTVTHPWASSGVSILSSSP--------SPPALA 357
            +++  TA           + S+P       T P ASS  S LS++P        S    +
Sbjct: 3496 NSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQAS 3555

Query: 358  SSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPS 399
            SSP  +  ++ R    S G      S S T+   SS  ++ S
Sbjct: 3556 SSPATLQVTTMRMSTPSEG------SSSLTTMLLSSTYVTSS 3591



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 95/430 (22%), Positives = 158/430 (36%), Gaps = 58/430 (13%)

Query: 23   SQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPA--TSPIGASGVAHRSQSSE 80
            S+ +T  T+P   N P      ++  P  + G ++   TP+  ++P+    V+    +S 
Sbjct: 998  SEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASS 1057

Query: 81   GVSSLSSSPSN-SLETQSQSLSRSQSMDIDGVSCEKS----------------------- 116
              S+LS++P++ S    + S + S S   DG S   S                       
Sbjct: 1058 ETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSE 1117

Query: 117  ---MSQVDVDSGIENMEVDENDRREKRSLSDKEPSSGP-EVSEEQALQLVCKIFRVSWKD 172
               +S   VD+ I      E       +     P+S P E +   A   V     VS + 
Sbjct: 1118 ASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSE- 1176

Query: 173  RDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDEN--PFASLTATSQ 230
                    ++LS     +  +V +  +        EV  M T T  E   P  S+     
Sbjct: 1177 -------ANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHT 1229

Query: 231  PIAAAARSP------DRNLLLNTGSNPGTSPMFCSVASFGASSLS---SLYESSPAPTPS 281
            P+A++  S       D +  + T +   +SP      S   S+ S   +L  S P  T  
Sbjct: 1230 PVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTL 1289

Query: 282  FWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTV----TH 337
              S  P     L +P      +   +   S  + A GT+  +   S    P T     T 
Sbjct: 1290 VTS--PEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTT 1347

Query: 338  PWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRIS 397
              ASS +SILS++P      S+P      +     +S G  +P ++PS  +   +S+ +S
Sbjct: 1348 LVASSAISILSTTPVDN---STPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVS 1404

Query: 398  PSLGASGGAS 407
             +   S  AS
Sbjct: 1405 TTPVVSSEAS 1414



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 85/394 (21%), Positives = 156/394 (39%), Gaps = 43/394 (10%)

Query: 22   TSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPA--TSPIGASGVAHRSQSS 79
            +S+ +T  T+P   + P      ++  P+ + G ++    P+  T+P+ +  V+     S
Sbjct: 2411 SSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVS 2470

Query: 80   EGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREK 139
                +LS++P ++    + S   S S                  +  E++ V  +   E 
Sbjct: 2471 SEAGTLSTTPVDTSTPMTTSTEASSS-----------------PTTAEDIVVPISTASEG 2513

Query: 140  RSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFK 199
             +L    P S   V+  +A  L       +        I  S+ SA+    P   +S+  
Sbjct: 2514 STLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSE-- 2571

Query: 200  DLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGT---SPM 256
               G   +  + +ST+     P AS  A++        S        T S+P T   + M
Sbjct: 2572 ---GSTPLRSMPVSTK-----PLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSM 2623

Query: 257  FCSVASFGASSLSSLYESS---PAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPH 313
              S  S  ++SL+S+  S+    +   S  S+ PV   +L + S   S     S+P +  
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTS-----SSPTTAE 2678

Query: 314  SAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPS 373
             ++  T+   + S+P       T   A+S  S LS++P      S+P    A +S    +
Sbjct: 2679 GSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVD---TSTPVTTSAEASSSPTT 2735

Query: 374  STGPPLPPASPSATSRRPSSLRISPSLGASGGAS 407
            + G  +  ++PS  S   +S+ +S    AS  AS
Sbjct: 2736 AEGTSMRISTPSDGSTPLTSILVSTLPVASSEAS 2769



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 89/425 (20%), Positives = 161/425 (37%), Gaps = 58/425 (13%)

Query: 23  SQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGV 82
           S+ +TPLT     N P   I  ++   S +  + V + T  T+   AS     ++ +   
Sbjct: 389 SEGSTPLT-----NMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIA 443

Query: 83  SSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREKRSL 142
           +S  S  S  L +   S +   S +   +S     S+  V +  E          E  S+
Sbjct: 444 TSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPT--AEVNSM 501

Query: 143 SDKEPSSGPEVSEEQALQLV----CKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDF 198
               PS G       ++  +     +   +S    D      +S  A       E  S  
Sbjct: 502 PTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTS-- 559

Query: 199 KDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFC 258
                      +  ST +    P  ++  +++ + ++  S        T + P  S  F 
Sbjct: 560 -----------IPTSTPSEGSTPLTNMPVSTRLVVSSEAS-------TTSTTPADSNTFV 601

Query: 259 SVASFGASSLSSLYESSPAPTPSF---WSSVPVMGPS--LASPSRAASQLAVP---STPL 310
           + +S  ASS S+  E +  PT ++    +++  M  S  L + S A++    P   +TP+
Sbjct: 602 TTSS-EASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPV 660

Query: 311 SPHSAASGTAAGSQPSSPRYRPYTV-----------THPWASSGVSILSSSPSPPALASS 359
           +  + A+ ++  ++ +S     YT            T   ASS  S LS++P      S+
Sbjct: 661 TTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVD---TST 717

Query: 360 PQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDS----YSDH 415
           P      +S    ++ G  +P ++PS  S   +S+ +S +L  S  AS   +     S H
Sbjct: 718 PVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTH 777

Query: 416 FTIET 420
            T  T
Sbjct: 778 ITTST 782



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 91/406 (22%), Positives = 142/406 (34%), Gaps = 68/406 (16%)

Query: 26   TTPLTSPQRENPPGPPI-----------AASAPGPSQSLGLNVHNMTPATSPIGASGVAH 74
            TTP+ SP+       P+            +S+P P++   +     +   +P+ +  V+ 
Sbjct: 2111 TTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVST 2170

Query: 75   RSQSSEGVSSLSSSP-SNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDE 133
               +S  +S+LS++P   S    + + +RS     +G S   S                 
Sbjct: 2171 TVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPS-------------- 2216

Query: 134  NDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKE 193
                E  +     P S   V   +A  L       S           S  +A+    P  
Sbjct: 2217 ----EGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTS 2272

Query: 194  VFSDFKDLIGQILM--------EVLMMSTQTRDEN-PFASLTATSQPIAAAARSPDRNLL 244
              S+    +  I +        EV  +ST   D N PF + T  S P   A  +      
Sbjct: 2273 TLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTST 2332

Query: 245  LNTGSNPGTSPMFCS--VASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQ 302
             + G+ P T     +  VASF  S+LS+    +PA T     S PV   S A        
Sbjct: 2333 SSEGNTPLTRMPVSTTMVASFETSTLST----TPADT-----STPVTTYSQAG------- 2376

Query: 303  LAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSP---SPPALASS 359
                S+P +    +  T+  S+ S+P       T P  SS  S  S++P   S P   S+
Sbjct: 2377 ----SSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTST 2432

Query: 360  PQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGG 405
                 ASSS      T  P  P S   T      +  +P + +  G
Sbjct: 2433 ----EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAG 2474



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 100/437 (22%), Positives = 169/437 (38%), Gaps = 72/437 (16%)

Query: 23   SQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPA--TSPIGASGVAHRSQS-S 79
            S+ +TPLT        G P++ +   P  S  ++  + TP   ++P+  S  AH S + S
Sbjct: 3101 SEGSTPLT--------GVPVSTT---PVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTS 3149

Query: 80   EGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIE-NMEVDENDRRE 138
            EG S  +S+PS    T    +  S  + +       S + VD  + +  + E   +   E
Sbjct: 3150 EGTSMPTSTPSEG-STPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAE 3208

Query: 139  KRSLSDKEPSSGPE------VSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPK 192
              S+    PS G        VS          I   +  D +  +   +  S+       
Sbjct: 3209 GTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEG 3268

Query: 193  EVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTAT----------------SQPIAAAA 236
                      G   +  + +ST T   +  ++L+ T                S PIA   
Sbjct: 3269 TSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGT 3328

Query: 237  RSPDRNLLLNTGSNPGTSPMFCS--VASFGASSLSSL-----------YESSPAPTPSFW 283
              P      + GS P T+  F +  V S  AS+LS+             E+S +PT +  
Sbjct: 3329 SMPTSTY--SEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEG 3386

Query: 284  SSVPVMGPS-----LAS------PSRAASQLAVPSTPLSPHS-AASGTAAGSQPSSPRYR 331
            +S+P   PS     LAS      P  ++    + +TP+  ++   + T A S P+     
Sbjct: 3387 TSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGT 3446

Query: 332  PY-TVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRR 390
               T T    S+ +SI+  S +P  +ASS     AS+    P  T  P+  +SP+ +S  
Sbjct: 3447 SLPTSTTSEGSTPLSIMPLSTTP--VASS----EASTLSTTPVDTSTPVTTSSPTNSSPT 3500

Query: 391  PSSLRISPSLGASGGAS 407
             + +   P+  A  G++
Sbjct: 3501 TAEVTSMPTSTAGEGST 3517



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 82/397 (20%), Positives = 146/397 (36%), Gaps = 51/397 (12%)

Query: 22   TSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPA--TSPIGASGVAHRSQSS 79
            +S+ +T  T+P   + P       +  P+ + G ++   TP+  T+P+    V+     S
Sbjct: 1999 SSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVS 2058

Query: 80   EGVSSLSSSP-------SNSLETQSQSLSRSQSMDIDGVS------CEKSMSQVDV---- 122
               ++LS++P       +NS E  S + +   SM I   S          +S   V    
Sbjct: 2059 SEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPE 2118

Query: 123  DSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSS 182
             S +    VD N       ++  E SS P  +E  ++Q        ++ DR   +  +  
Sbjct: 2119 ASTLSTTPVDSN----SPVITSTEVSSSPIPTEGTSMQ------TSTYSDRRTPLTSM-- 2166

Query: 183  LSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRN 242
                    P          I  +    +  ST   +     S   TS+  +    +P   
Sbjct: 2167 --------PVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEG 2218

Query: 243  LLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQ 302
                T     T P+  S AS    S + +  S+P  T +  +S P      + P+   S 
Sbjct: 2219 STPFTSMPVSTMPVVTSEAS--TLSATPVDTSTPVTTSTEATSSPTTAEGTSIPT---ST 2273

Query: 303  LAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQA 362
            L+  +TPL+    +    A S+ S+    P     P+ +S     + + SPP  A     
Sbjct: 2274 LSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTS-----TEASSPPPTAEGTSM 2328

Query: 363  VPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPS 399
              ++SS      T   +P ++    S   S+L  +P+
Sbjct: 2329 PTSTSSEGNTPLT--RMPVSTTMVASFETSTLSTTPA 2363



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 6/188 (3%)

Query: 207  MEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGAS 266
            +  L++ST      P AS+ +T     +   +P  +   +T + P  + +  SV + G++
Sbjct: 3876 LTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTA-STPTIPVATTISVSVITEGST 3934

Query: 267  SLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPS 326
              ++++  S   T S     P    ++++P   +++L  PST     S++S T + S   
Sbjct: 3935 PGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPST-----SSSSTTTSFSTTK 3989

Query: 327  SPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSA 386
                   T   P     +S   S+P   +   +  A   S++    +ST     P +PS+
Sbjct: 3990 EFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSS 4049

Query: 387  TSRRPSSL 394
             S RPS++
Sbjct: 4050 ESSRPSTI 4057



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 52/216 (24%), Positives = 85/216 (39%), Gaps = 22/216 (10%)

Query: 208  EVLMMSTQTRDEN--PFASLTATSQPIAAAARSP------DRNLLLNTGSNPGTSPMFCS 259
            EV  M T T  E   P  S+     P+A++          D +  + T +   +SP   +
Sbjct: 2796 EVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSP---T 2852

Query: 260  VASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGT 319
             A      +S+  E S   T    S+ PV     ++ S      ++P T  +  S++  T
Sbjct: 2853 TAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTT 2912

Query: 320  AAG--------SQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQR 371
            A G        S+ S+P       T P A S  S LS++P       +P    A +S   
Sbjct: 2913 AEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVD---TRTPVTTSAEASSSP 2969

Query: 372  PSSTGPPLPPASPSATSRRPSSLRISPSLGASGGAS 407
             ++ G  +P ++P       +S+ +S    AS  AS
Sbjct: 2970 TTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEAS 3005



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 49/206 (23%), Positives = 85/206 (41%), Gaps = 13/206 (6%)

Query: 212  MSTQTRDENPFASLTATSQPIAAAARSP------DRNLLLNTGSNPGTSPMFCSVASFGA 265
            +ST +    P  S+  ++ P+A    S       D N  + T +   +SP      S   
Sbjct: 3038 ISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPI 3097

Query: 266  SSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVP-STPLSPHSAASGTAAGSQ 324
            S+ S   E S   T    S+ PV   ++++ S      + P +T    HS+ + +   S 
Sbjct: 3098 STYS---EGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSM 3154

Query: 325  PSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSST---GPPLPP 381
            P+S      T       S + ++SS  S  +      + P ++S +  SST   G  +P 
Sbjct: 3155 PTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPT 3214

Query: 382  ASPSATSRRPSSLRISPSLGASGGAS 407
            ++PS      +S+ +S +  AS  AS
Sbjct: 3215 STPSEGMTPLTSVPVSNTPVASSEAS 3240



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 48/204 (23%), Positives = 77/204 (37%), Gaps = 30/204 (14%)

Query: 213  STQTRDENPFASLTATSQPIAAAARSPDRNLLL-NTGSNPGTSPMF------CSVASFGA 265
            ST T         T  S  +     +P   + + +T     T+ +F       S     +
Sbjct: 3909 STDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITS 3968

Query: 266  SSLSSLYESSPAPTPSFWSSVPVMGPSL--ASPSRAASQLAVPSTPLS------------ 311
            + L++   SS + T SF ++     P++  A+P    +    PSTP +            
Sbjct: 3969 TELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTL 4028

Query: 312  -----PHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASS----PQA 362
                 PH++ S T     PSS   RP T+T            SS  P   ASS    P+A
Sbjct: 4029 SATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEA 4088

Query: 363  VPASSSRQRPSSTGPPLPPASPSA 386
            V   ++R +PS+     P  + +A
Sbjct: 4089 VTTMTTRTKPSTRTTSFPTVTTTA 4112



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 98/448 (21%), Positives = 168/448 (37%), Gaps = 66/448 (14%)

Query: 22   TSQPTTPLT---SPQRENPPGPPIAASAPGPSQSLGLNVHNMTPAT-------SPIGASG 71
            TS PT+  T   +P    P    + AS+   + S    V   TP T       SP  A G
Sbjct: 676  TSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLST-TPVDTSTPVTTSTEASSSPTTADG 734

Query: 72   VAH-RSQSSEGVSSLSSSP-SNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENM 129
             +   S  SEG + L+S P S +L T S++ + S +          S       +  E  
Sbjct: 735  ASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGT 794

Query: 130  EVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQ 189
             +  +   E   L    P S   V+  +A  L       +        +  S   A+   
Sbjct: 795  SMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTS 854

Query: 190  NPKEVFSDFKDLIGQILMEVLMMSTQ---TRDENPFASLT------------ATSQPIAA 234
             P   +S+ +  +  + +   +++T    T    P  + T             TS+  + 
Sbjct: 855  MPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM 914

Query: 235  AARSPDRNLLLNTGSNPGTSPMFCSVASFGASS-------LSSLYESSPAPTPSFWSSVP 287
               +P       T     T+P+  S A   +++       +++  E++ +PT +  +S+P
Sbjct: 915  PTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 974

Query: 288  VMGPS--------------LASPSRAASQLAVP---STPLSPHSAASG-----------T 319
               PS              L + S A++    P   +TPL+  + AS            T
Sbjct: 975  TSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPT 1034

Query: 320  AAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPL 379
            +  S+ S+P  R    T   ASS  S LS++   PA  S+P    + +S    ++ G  +
Sbjct: 1035 STPSEGSTPLTRMPVSTTMVASSETSTLSTT---PADTSTPVTTYSQASSSSTTADGTSM 1091

Query: 380  PPASPSATSRRPSSLRISPSLGASGGAS 407
            P ++ S  S   +S+ +S  L  S  AS
Sbjct: 1092 PTSTYSEGSTPLTSVPVSTRLVVSSEAS 1119



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 89/449 (19%), Positives = 160/449 (35%), Gaps = 102/449 (22%)

Query: 26   TTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQS-SEGVSS 84
            TT + S +  +    P   S P  + S          ++SP  A G + ++ + SEG + 
Sbjct: 1523 TTTVASSEINSLSTTPAVTSTPVTTYSQA--------SSSPTTADGTSMQTSTYSEGSTP 1574

Query: 85   LSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREKRSLSD 144
            L+S P +++   S   +   +  ID  +   + ++    +  E   +  +   E   L  
Sbjct: 1575 LTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLT 1634

Query: 145  KEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQ 204
              P S   V+  +A  L       S    D +   ++S        P E  S        
Sbjct: 1635 SIPVSTTPVASPEASTL-------STTPVDSNSPVITSTEVSSSPTPAEGTS-------- 1679

Query: 205  ILMEVLMMSTQTRDENPFASLTATSQPIAAAARSP------------------------- 239
                 +  ST T    P  S+T  + P+A++A S                          
Sbjct: 1680 -----MPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTS 1734

Query: 240  DRNLLLNTGSNPGTSPMFC------SVASFGASSLSSL-----------YESSPAPTPSF 282
            +   + N+  + GT+P+         V S  AS+LS+             E++ +PT + 
Sbjct: 1735 EGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAE 1794

Query: 283  WSSVPV------MGPSLASP----------------------SRAASQLAVPSTPLSPHS 314
             +S+P       M P  ++P                      S   +  AV S+P     
Sbjct: 1795 GTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEG 1854

Query: 315  AASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSS 374
             +  T+  S+ S+        T   ASS  + LS++   PA+ S+P    A  S    ++
Sbjct: 1855 TSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTT---PAVTSTPVTTYAQVSSSPTTA 1911

Query: 375  TGPPLPPASPSATSRRPSSLRISPSLGAS 403
             G  +P ++P       +S+ +S +  AS
Sbjct: 1912 DGSSMPTSTPREGRPPLTSIPVSTTTVAS 1940



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 84/431 (19%), Positives = 163/431 (37%), Gaps = 70/431 (16%)

Query: 26   TTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPA--TSPIGASGVAHRSQSSEGVS 83
            TTP+ S   +        AS+P P+  +  ++   TP   ++P+ +  V H   +S   S
Sbjct: 1182 TTPVDS---KTQVATSTEASSPPPTAEV-TSMPTSTPGERSTPLTSMPVRHTPVASSEAS 1237

Query: 84   SLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREKRSLS 143
            +LS+SP ++    + S   S S                  +  E   +  +   E  +L 
Sbjct: 1238 TLSTSPVDTSTPVTTSAETSSS-----------------PTTAEGTSLPTSTTSEGSTLL 1280

Query: 144  DKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIG 203
               P S   V+  +A  L+             + +  S   A+    P   +S+ +  + 
Sbjct: 1281 TSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLT 1340

Query: 204  QILMEVLMMSTQT---RDENPFASLT--ATSQPIAAAARSPDRNLLLNTGSNPGTSPMFC 258
             I +   ++++         P  + T   TS    ++  + +   + N+  + GT+P+  
Sbjct: 1341 SIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTS 1400

Query: 259  ------SVASFGASSLSS--LYESSPAPTPSFWSSVPVMGPSLASPSRAASQ-------L 303
                   V S  AS+LS+  +  S+P  T +  +S P     ++ P+   S+       +
Sbjct: 1401 IPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSI 1460

Query: 304  AVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTH-PWASSGVSILSSSPSP--------- 353
             V +TP++   A++ +      +SP      V+  P  + G SI  S+PS          
Sbjct: 1461 PVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIP 1520

Query: 354  -----------------PALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRI 396
                             PA+ S+P    + +S    ++ G  +  ++ S  S   +SL +
Sbjct: 1521 VSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPV 1580

Query: 397  SPSLGASGGAS 407
            S  L  S  A+
Sbjct: 1581 STMLVVSSEAN 1591



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 48/188 (25%), Positives = 82/188 (43%), Gaps = 13/188 (6%)

Query: 213  STQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLY 272
            ST +    P  S+  ++ P+ ++  S      ++T S P T+    S +   A   +S+ 
Sbjct: 2390 STYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDT-STPVTTSTEASSSPTTAEG-TSIP 2447

Query: 273  ESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVP---STPLSPHSAASGTAAGSQPSSPR 329
             S P+   +  +S+PV    + S S A +    P   STP++     + T A S P++  
Sbjct: 2448 TSPPSEGTTPLASMPVSTTPVVS-SEAGTLSTTPVDTSTPMT-----TSTEASSSPTTAE 2501

Query: 330  YRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSR 389
                 V    AS G ++L+S P      +SP+A   S++    +S        S SATS 
Sbjct: 2502 --DIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSA 2559

Query: 390  RPSSLRIS 397
              +S+  S
Sbjct: 2560 EGTSMPTS 2567



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 104/452 (23%), Positives = 166/452 (36%), Gaps = 85/452 (18%)

Query: 23   SQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPAT-------SPIGASGVA-H 74
            S+ +TPLTS      P     AS    +      V   TP T       SP  A G +  
Sbjct: 2393 SEGSTPLTSVPVSTMPVVSSEASTHSTTP-----VDTSTPVTTSTEASSSPTTAEGTSIP 2447

Query: 75   RSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDG-----VSCEKSMSQVDVDSGIENM 129
             S  SEG + L+S P ++    S       +  +D       S E S S        E++
Sbjct: 2448 TSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTA----EDI 2503

Query: 130  EVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQ 189
             V  +   E  +L    P S   V+  +A  L       +        I  S+ SA+   
Sbjct: 2504 VVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTS 2563

Query: 190  NPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTAT----SQPIAAAARSPDRNLLL 245
             P   +S+     G   +  + +ST+    +  ++L+ T    S P+  +  +       
Sbjct: 2564 MPTSTYSE-----GSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTA 2618

Query: 246  NTGSNPGTSPMFCS------------VASFGASSLSSL-----------YESSPAPTPSF 282
               S P ++P   S            VAS  AS+LS+              +S +PT + 
Sbjct: 2619 KDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAE 2678

Query: 283  WSSVPVMGP--------------SLASPSRAASQLAVP---STPLSPHSAASG---TAAG 322
             SS+P   P              +L + S A++    P   STP++  + AS    TA G
Sbjct: 2679 GSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEG 2738

Query: 323  --------SQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSS 374
                    S  S+P       T P ASS  S +S++       S P      +S    ++
Sbjct: 2739 TSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVD---TSIPVTTSTEASSSPTTA 2795

Query: 375  TGPPLPPASPSATSRRPSSLRISPSLGASGGA 406
                +P ++PS TS   +S+ ++ +  AS  A
Sbjct: 2796 EVTSMPTSTPSETSTPLTSMPVNHTPVASSEA 2827



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 77/391 (19%), Positives = 140/391 (35%), Gaps = 52/391 (13%)

Query: 26   TTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSSL 85
            TTP+ S +       P+  S P  + S      N +P T+ + +      S + EG + L
Sbjct: 3467 TTPVASSEASTLSTTPVDTSTPVTTSS----PTNSSPTTAEVTSMPT---STAGEGSTPL 3519

Query: 86   SSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSG---IENMEVDENDRREKRSL 142
            ++ P ++    S   S   +  +D  +   S SQ         +  M +         SL
Sbjct: 3520 TNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSS-SL 3578

Query: 143  SDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLI 202
            +    SS    S E +      +        DR     +S  +     P EV +      
Sbjct: 3579 TTMLLSSTYVTSSEASTPSTPSV--------DRSTPVTTSTQSNSTPTPPEVIT------ 3624

Query: 203  GQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVAS 262
                   L MST +    P   +  ++  +  +       L ++T +   TS    S   
Sbjct: 3625 -------LPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPV 3677

Query: 263  FGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAG 322
                +   ++  S   TP     V     + +  S  ++   V STP++  + A  ++A 
Sbjct: 3678 TPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSAT 3737

Query: 323  SQPSSPRYRPYTVTHPWASS--GVSIL-----------SSSPSPPALASSPQAVPASSSR 369
               ++      +V+ P   S  G +IL           SS+PS P++ +S     AS   
Sbjct: 3738 LDSTT-----MSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGS 3792

Query: 370  QRPSST--GPPLPPASPSATSRRPSSLRISP 398
              P++      +P ++ S  S   +++ ISP
Sbjct: 3793 SSPTTLEGTTTMPMSTTSERSTLLTTVLISP 3823



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 41/197 (20%), Positives = 78/197 (39%), Gaps = 17/197 (8%)

Query: 221  PFASLTATSQPIAAAARSP-DRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPT 279
            P ++    S   +  + +P D N  + T +   +SP    + + G S  +S Y     P 
Sbjct: 2108 PLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSP----IPTEGTSMQTSTYSDRRTPL 2163

Query: 280  PSFWSSVPVMGPSLASP---------SRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRY 330
             S   S  V+  S  S          +   +     S+P +    +  T+  S+ S+P  
Sbjct: 2164 TSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFT 2223

Query: 331  RPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRR 390
                 T P  +S  S LS++P      S+P      ++    ++ G  +P ++ S  +  
Sbjct: 2224 SMPVSTMPVVTSEASTLSATPVD---TSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTP 2280

Query: 391  PSSLRISPSLGASGGAS 407
             +S+ +S +L A+   S
Sbjct: 2281 LTSIPVSHTLVANSEVS 2297


>gi|149408144 TOX high mobility group box family member 2 isoform a
           [Homo sapiens]
          Length = 506

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 96/402 (23%), Positives = 145/402 (36%), Gaps = 79/402 (19%)

Query: 38  PGPPIAASAPGPSQSLGLNVHNMTPATSPIGA-SGVAHRSQSSEGVSSLSSSPSNSLETQ 96
           PGP +   A   S    L+   +    S +G  S +AH S S  G  S + SPS+S + +
Sbjct: 154 PGPLLGRPAMLASHMSALSQSQLI---SQMGIRSSIAHSSPSPPGSKSATPSPSSSTQEE 210

Query: 97  SQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEE 156
              +          +S EK  S    D G    +  +N +++K+    K+P+   +    
Sbjct: 211 ESEVHFK-------ISGEKRPS---ADPG----KKAKNPKKKKK----KDPNEPQKPVSA 252

Query: 157 QALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFK-------DLIGQILMEV 209
            AL                   F  + +A   QNP   F D         D +G+   + 
Sbjct: 253 YAL------------------FFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQA 294

Query: 210 LMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTS------PMFC--SVA 261
               T+   +    +L A    + + + SPD+    +T +NP         PM+    +A
Sbjct: 295 YKRKTEAAKKEYLKALAAYRASLVSKS-SPDQGETKSTQANPPAKMLPPKQPMYAMPGLA 353

Query: 262 SFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAA 321
           SF   S    + S  +P     S    +G     P  +AS    PS PLSP         
Sbjct: 354 SFLTPSDLQAFRSGASPA----SLARTLGSKSLLPGLSASPPPPPSFPLSP-------TL 402

Query: 322 GSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPP 381
             Q S P +    +  P  S     +S +P PP L +     P +   Q   S  PP P 
Sbjct: 403 HQQLSLPPHAQGALLSPPVS-----MSPAPQPPVLPT-----PMALQVQLAMSPSPPGPQ 452

Query: 382 ASPSATSRRPSSLRISPSLGASGGASNWDSY--SDHFTIETC 421
             P  +    SS   SP       + +WDS   S    I TC
Sbjct: 453 DFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGISTC 494


>gi|149408141 TOX high mobility group box family member 2 isoform c
           [Homo sapiens]
          Length = 464

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 96/402 (23%), Positives = 145/402 (36%), Gaps = 79/402 (19%)

Query: 38  PGPPIAASAPGPSQSLGLNVHNMTPATSPIGA-SGVAHRSQSSEGVSSLSSSPSNSLETQ 96
           PGP +   A   S    L+   +    S +G  S +AH S S  G  S + SPS+S + +
Sbjct: 112 PGPLLGRPAMLASHMSALSQSQLI---SQMGIRSSIAHSSPSPPGSKSATPSPSSSTQEE 168

Query: 97  SQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEE 156
              +          +S EK  S    D G    +  +N +++K+    K+P+   +    
Sbjct: 169 ESEVHFK-------ISGEKRPS---ADPG----KKAKNPKKKKK----KDPNEPQKPVSA 210

Query: 157 QALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFK-------DLIGQILMEV 209
            AL                   F  + +A   QNP   F D         D +G+   + 
Sbjct: 211 YAL------------------FFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQA 252

Query: 210 LMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTS------PMFC--SVA 261
               T+   +    +L A    + + + SPD+    +T +NP         PM+    +A
Sbjct: 253 YKRKTEAAKKEYLKALAAYRASLVSKS-SPDQGETKSTQANPPAKMLPPKQPMYAMPGLA 311

Query: 262 SFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAA 321
           SF   S    + S  +P     S    +G     P  +AS    PS PLSP         
Sbjct: 312 SFLTPSDLQAFRSGASPA----SLARTLGSKSLLPGLSASPPPPPSFPLSP-------TL 360

Query: 322 GSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPP 381
             Q S P +    +  P  S     +S +P PP L +     P +   Q   S  PP P 
Sbjct: 361 HQQLSLPPHAQGALLSPPVS-----MSPAPQPPVLPT-----PMALQVQLAMSPSPPGPQ 410

Query: 382 ASPSATSRRPSSLRISPSLGASGGASNWDSY--SDHFTIETC 421
             P  +    SS   SP       + +WDS   S    I TC
Sbjct: 411 DFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGISTC 452


>gi|14249636 TOX high mobility group box family member 2 isoform c
           [Homo sapiens]
          Length = 464

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 96/402 (23%), Positives = 145/402 (36%), Gaps = 79/402 (19%)

Query: 38  PGPPIAASAPGPSQSLGLNVHNMTPATSPIGA-SGVAHRSQSSEGVSSLSSSPSNSLETQ 96
           PGP +   A   S    L+   +    S +G  S +AH S S  G  S + SPS+S + +
Sbjct: 112 PGPLLGRPAMLASHMSALSQSQLI---SQMGIRSSIAHSSPSPPGSKSATPSPSSSTQEE 168

Query: 97  SQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEE 156
              +          +S EK  S    D G    +  +N +++K+    K+P+   +    
Sbjct: 169 ESEVHFK-------ISGEKRPS---ADPG----KKAKNPKKKKK----KDPNEPQKPVSA 210

Query: 157 QALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFK-------DLIGQILMEV 209
            AL                   F  + +A   QNP   F D         D +G+   + 
Sbjct: 211 YAL------------------FFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQA 252

Query: 210 LMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTS------PMFC--SVA 261
               T+   +    +L A    + + + SPD+    +T +NP         PM+    +A
Sbjct: 253 YKRKTEAAKKEYLKALAAYRASLVSKS-SPDQGETKSTQANPPAKMLPPKQPMYAMPGLA 311

Query: 262 SFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAA 321
           SF   S    + S  +P     S    +G     P  +AS    PS PLSP         
Sbjct: 312 SFLTPSDLQAFRSGASPA----SLARTLGSKSLLPGLSASPPPPPSFPLSP-------TL 360

Query: 322 GSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPP 381
             Q S P +    +  P  S     +S +P PP L +     P +   Q   S  PP P 
Sbjct: 361 HQQLSLPPHAQGALLSPPVS-----MSPAPQPPVLPT-----PMALQVQLAMSPSPPGPQ 410

Query: 382 ASPSATSRRPSSLRISPSLGASGGASNWDSY--SDHFTIETC 421
             P  +    SS   SP       + +WDS   S    I TC
Sbjct: 411 DFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGISTC 452


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 41/151 (27%), Positives = 65/151 (43%), Gaps = 17/151 (11%)

Query: 273 ESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTP--LSPHSAASGTAAGSQPSSPRY 330
           ++SPAP P   ++ P+ GP  +S      Q  +  +P   SPH           PS P  
Sbjct: 753 QASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPT-------RPPSRPPS 805

Query: 331 RPYTVTHPWASSGVSILSSSPSPPAL-----ASSPQAVPASSSRQRPSSTGPPLPPASPS 385
           RP +V+ P +   +       +PP L       +   VP  +S   P++ GPP PP  P 
Sbjct: 806 RPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQ 865

Query: 386 ATSRR---PSSLRISPSLGASGGASNWDSYS 413
           +       P +  + PS  +S  AS+ ++ S
Sbjct: 866 SQPPEGPLPPAPHLPPSSTSSAVASSSETSS 896



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 38/163 (23%), Positives = 61/163 (37%), Gaps = 18/163 (11%)

Query: 276  PAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTV 335
            P P P  +  V    P+L  P     +     + +   + A G  A  Q S       T 
Sbjct: 936  PPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTS-------TS 988

Query: 336  THPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTG-PPLPPASPSATSRRPSSL 394
              P  S   S+L S  +P    ++P   PA +     ++TG PPL PA   A +    +L
Sbjct: 989  LGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPM---AATGLPPLLPAENKAFASNLPTL 1045

Query: 395  RISPSLGASGGASNWDSYSDHF-------TIETCKETDMLNYL 430
             ++ +  +  G  +   Y           T++  KE   L +L
Sbjct: 1046 NVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHL 1088



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 38/148 (25%), Positives = 59/148 (39%), Gaps = 33/148 (22%)

Query: 289 MGPSLASPSRAASQLAVPSTPLSPHSAAS-----GTAAGSQPSSPRYRPYTVTHPWASSG 343
           +GP LA  S A S   + + P+     A        AAGS P+  +  P          G
Sbjct: 526 LGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQG 585

Query: 344 VSILSSS------------PSPPALAS-----------SPQAVPASSSR-----QRPSST 375
           V++  S+            P+ PA A+           +PQA PA S+      Q+P + 
Sbjct: 586 VTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQ 645

Query: 376 GPPLPPASPSATSRRPSSLRISPSLGAS 403
            PP  P   +A   + ++ + SP L +S
Sbjct: 646 QPPQAPTPQAAAPPQATTPQPSPGLASS 673


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 52/160 (32%), Positives = 72/160 (45%), Gaps = 24/160 (15%)

Query: 251 PGTSPMFCSVASF--GASSLSSLYESSPAPT---------PSFWSSVPVMGPSLASPSRA 299
           P  SP+  S ASF  G+S      ES+P P+         PSF  S   +  +L+    A
Sbjct: 534 PAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTA 593

Query: 300 ASQLAVPST-----PLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSS-PSP 353
           A+     S+     P+SP S+AS  AA    S P   P  ++ P   S V + SS  PSP
Sbjct: 594 AATSTPVSSSQSAPPMSPFSSASKPAA----SGPLSHPTPLSAP--PSSVPLKSSVLPSP 647

Query: 354 PALASSPQAVPASSSRQR-PSSTGPPLPPASPSATSRRPS 392
              ++   + P  S  Q+ P  T P   P SP A S +P+
Sbjct: 648 SGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPA 687



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 96/402 (23%), Positives = 148/402 (36%), Gaps = 68/402 (16%)

Query: 19   GGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQ----SLGLNVHNMTPATSPIGASGVAH 74
            G Q +  T P ++P       PP  A+ P P+     S G  + + T  + P+ A     
Sbjct: 1442 GSQQTNSTVPPSAP-------PPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTE 1494

Query: 75   RSQSSE-----GVSSLSSSPSNSLETQ-SQSLSRSQSMDIDGVSCEKSMSQVDVD----- 123
             + SS      G S +S+S ++ LE Q S  L ++     D V  E  ++Q  V      
Sbjct: 1495 EATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTA 1554

Query: 124  -SGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSS 182
             S    + +          + D    + P  S           F V  +         S+
Sbjct: 1555 ASSTSLVALSAEATPATTGVPDARTEAVPPASS----------FSVPGQTAVTAAAISSA 1604

Query: 183  LSAQFKQNPKEVFSDFKDLIGQ-ILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDR 241
                 + +   + S    ++      E     T T   + FA      QP AA++ S   
Sbjct: 1605 GPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFA------QPPAASSSSAFN 1658

Query: 242  NLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAAS 301
             L  NT + P  +P+F  VA+  A SL      S A T            + A+P  ++S
Sbjct: 1659 QLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTAST------------AAATPQVSSS 1706

Query: 302  QLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQ 361
              + P         A GT A        +   +V    ASS  S+ S   S P  +S P 
Sbjct: 1707 GFSSP---------AFGTTAPGVFGQTTFGQASVFGQSASSAASVFSF--SQPGFSSVPA 1755

Query: 362  -AVPASSSRQRPSST-GPPLPPASPSATSRRPSSLRISPSLG 401
               PASS+   P+ST G     AS +++S   S  + SP+ G
Sbjct: 1756 FGQPASST---PTSTSGSVFGAASSTSSSSSFSFGQSSPNTG 1794



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 52/208 (25%), Positives = 79/208 (37%), Gaps = 24/208 (11%)

Query: 223  ASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSF 282
            +S T  S P++A  RS +          PG S +  S AS      S+    +P  T   
Sbjct: 1478 SSATTPSLPMSAG-RSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDS 1536

Query: 283  WSSVPVMG-PSLASPSRAASQL--------AVPST------------PLSPHSAASGTA- 320
                PV+  P++++   AAS          A P+T            P S  S    TA 
Sbjct: 1537 VKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAV 1596

Query: 321  -AGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPL 379
             A +  S+      T + P ASS  SI++  PS  A A       +S   Q P+++    
Sbjct: 1597 TAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSA 1656

Query: 380  PPASPSATSRRPSSLRISPSLGASGGAS 407
                 + T+  PS+  +   + AS   S
Sbjct: 1657 FNQLTNNTATAPSATPVFGQVAASTAPS 1684



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 4/147 (2%)

Query: 246 NTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAV 305
           +T + P +S     + +  A++ +SL  SSPA   + +S +P  G        ++S  + 
Sbjct: 433 STPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSS 492

Query: 306 PSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPA 365
            +    P S +SG+ +      P    ++   P  +S     ++SP  P+ AS       
Sbjct: 493 ATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAAS----FSF 548

Query: 366 SSSRQRPSSTGPPLPPASPSATSRRPS 392
            SS  +P+    P+P  S    + +PS
Sbjct: 549 GSSGFKPTLESTPVPSVSAPNIAMKPS 575



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 44/169 (26%), Positives = 68/169 (40%), Gaps = 24/169 (14%)

Query: 224  SLTATSQPIAA--AARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPS 281
            S   T  P+    AA    +  L+N+    G +P    ++S   +S ++  E++   TPS
Sbjct: 1146 STAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPS 1205

Query: 282  FWSSVPVMGPSLASPSRA----------------ASQLAVPSTPLSPHSAASGTAAGSQP 325
              +S     P   SPS                  A+Q A PST  S    A  +  GS+P
Sbjct: 1206 --ASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKP 1263

Query: 326  SSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSS 374
            S   Y     + P  S   S  +++P  PA +SS    P+ ++    SS
Sbjct: 1264 S---YEAIPESSP-PSGITSASNTTPGEPAASSSRPVAPSGTALSTTSS 1308



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 53/220 (24%), Positives = 82/220 (37%), Gaps = 30/220 (13%)

Query: 223  ASLTATSQPIAAAAR--SPDRNLLLNTGSNPGTSPMFCSVASFGAS-------SLSSLY- 272
            AS T   +P A+++R  +P    L  T S   T P       F +S       S S L  
Sbjct: 1280 ASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRV 1339

Query: 273  ---ESSPAPT------------PSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAAS 317
               + S  PT            P+  S VP  G +  +P         P T  +  ++ +
Sbjct: 1340 GQADDSTKPTNKASSTSLTSTQPTKTSGVP-SGFNFTAPPVLGKHTEPPVTSSATTTSVA 1398

Query: 318  GTAAGSQPSSPRYRPYTVTHPWASSGVSI----LSSSPSPPALASSPQAVPASSSRQRPS 373
              AA S  S+  +    VT   +S  +S     LS+  +  +  S         S   P+
Sbjct: 1399 PPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPT 1458

Query: 374  STGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYS 413
            +   PLP + P+ +     S   +PSL  S G S  ++ S
Sbjct: 1459 TAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATS 1498



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 44/204 (21%), Positives = 75/204 (36%), Gaps = 22/204 (10%)

Query: 215  QTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNP--GTSPMFCSVASF--------- 263
            +T  E+   SL      ++   ++  RN L    + P   T+P   S ++F         
Sbjct: 922  KTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDL 981

Query: 264  ----GASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAAS---QLAVPSTPLSPHSAA 316
                  SS+S   ES  A T        V  P  A   R  S    L   + P +     
Sbjct: 982  DEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLV 1041

Query: 317  SGTAAGSQPSSPRYRPYTVTHPWASSGV----SILSSSPSPPALASSPQAVPASSSRQRP 372
             G++ G   +S       +    A S +    ++   +PSP    S+PQA  A++ R++ 
Sbjct: 1042 HGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQM 1101

Query: 373  SSTGPPLPPASPSATSRRPSSLRI 396
            +S  P +   + S     P  + +
Sbjct: 1102 ASQAPAVNTLTESTLKNVPQVVNV 1125


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 46/207 (22%), Positives = 80/207 (38%), Gaps = 26/207 (12%)

Query: 219  ENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSP-- 276
            + P  +L++   P+ A+    +      +  +P T+      +  GA + S++   SP  
Sbjct: 818  DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKG 877

Query: 277  -------APTPSFWS--------------SVPVMGPSLASPSRAASQLAVPSTPLSPHSA 315
                    PTPS  +                P +  + +SP +A +  A    P SP   
Sbjct: 878  VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPK 937

Query: 316  ASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSST 375
             + T   + P SP+  P T +  WA +  +    SP       SP+  P   +   PS  
Sbjct: 938  GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997

Query: 376  GPPLPPA---SPSATSRRPSSLRISPS 399
            G P  P+   +P+  +  P S + SP+
Sbjct: 998  GGPATPSPKGAPTPPAVTPPSPKGSPA 1024



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 52/199 (26%), Positives = 81/199 (40%), Gaps = 27/199 (13%)

Query: 224  SLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFW 283
            +L A + P   + + P     + T S+P  +P   + A  GA +L ++  SSP   P+  
Sbjct: 1466 TLPAVTPP---SPKEPPAPKQVATSSSPKKAP--ATPAPMGAPTLPAVIPSSPKEVPATP 1520

Query: 284  SSV--PVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWAS 341
            SS   P+   +     +  + LA     + P              +P+  P T +   AS
Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS 1580

Query: 342  SGVSILSSS----PSP-------------PALASSPQAVPASSSRQRPSSTGPPLPPASP 384
            S  ++  S+    PSP             P  A +P AV   S  + P++  P   P SP
Sbjct: 1581 SPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640

Query: 385  SATSRRPSSLRISPSLGAS 403
              T   PSSL+ SP+  AS
Sbjct: 1641 PVT---PSSLKDSPTSPAS 1656



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 45/140 (32%), Positives = 63/140 (45%), Gaps = 18/140 (12%)

Query: 277  APTP-SFWSSVPVMGPSLASPSRAASQLAV--PST---PLSPHSAASGTAAGSQPSSPRY 330
            APTP +     P  GP+  SP  A +  A   PS    P +P    + T   + P SP+ 
Sbjct: 939  APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998

Query: 331  RPYTVTHPWASSGVSILSSSP--SPPAL-----ASSPQAVPASSSRQRPSSTGPPLP--- 380
             P T +   A +  ++   SP  SP A      AS+P A    S +  P++T  PLP   
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAAT--PLPKGA 1056

Query: 381  PASPSATSRRPSSLRISPSL 400
            P +P+AT   P     +PSL
Sbjct: 1057 PTTPAATLPSPKGGPATPSL 1076



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 38/137 (27%), Positives = 56/137 (40%), Gaps = 12/137 (8%)

Query: 277  APTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVT 336
            APTP   ++ P +   LA+P    +      TP SP    + +     P+ P   P +  
Sbjct: 1263 APTPPA-ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS-- 1319

Query: 337  HPWASSGVSILSSSPSPPALAS-SPQAVPASSSRQRPSSTGPPLPPAS------PSATSR 389
             P  S G      +P+PPA+   SP+  P   +   PSS G P  P+S      P+AT  
Sbjct: 1320 -PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT-PSSKGGPTTPSSKEGPTPPAATPS 1377

Query: 390  RPSSLRISPSLGASGGA 406
                  ++P     G A
Sbjct: 1378 HKGGPAMTPPSPKRGPA 1394



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 45/186 (24%), Positives = 68/186 (36%), Gaps = 16/186 (8%)

Query: 233  AAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPS 292
            AA   SP   L   +     T+P     A+   S    L   SP   P+  ++ P     
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTP-----AATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230

Query: 293  -LASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRP-------YTVTHPWASSGV 344
             LA+PS   +     +TP SP    +       P+ P   P        T  H  A +  
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290

Query: 345  SILSSSPSPPALASSPQAVPASSSRQRPSSTGP---PLPPASPSATSRRPSSLRISPSLG 401
             +   SP      S P+  P   +   PS  G    P P  +P+  +  P S + +P+L 
Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP 1350

Query: 402  ASGGAS 407
            A+  +S
Sbjct: 1351 ATTPSS 1356



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 50/187 (26%), Positives = 80/187 (42%), Gaps = 23/187 (12%)

Query: 230 QPIAAAARSPDRNLLLNTGS--NPG-TSPMFCSVASFGASSLSSLYESSPAPTPSFWSSV 286
           QP A  A  P  + L  T +   PG T P  CS A      LS+  ++SP P+PS  +S 
Sbjct: 18  QPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAP-QQCPLSAANQASPFPSPSTIAST 76

Query: 287 PVMGPSLASPSRAASQLAV-PSTP------LSPHSAASGTAAGSQPSSPRYRPYTVTHPW 339
           P+  P   S S  A  L   P  P      + P  + +  A     +SP   P     P 
Sbjct: 77  PLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALAL----ASPMIAPTLKGTPS 132

Query: 340 ASSGVSILSSSPS--------PPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRP 391
           +S+ +++++ +P         PP L +SP +V  + S    + + P  P    +  ++ P
Sbjct: 133 SSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVP 192

Query: 392 SSLRISP 398
           S +  +P
Sbjct: 193 SEVVPNP 199



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 40/142 (28%), Positives = 53/142 (37%), Gaps = 26/142 (18%)

Query: 266  SSLSSLYESSPAPT--PSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGS 323
            SS      ++PAP   P+  S      P  A+P       A PS   +P      T   +
Sbjct: 915  SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP------TPPAA 968

Query: 324  QPSSPRYRPYT-----------VTHPWASSGVSILS--SSPSPPALA-----SSPQAVPA 365
             P SP+  P T            T P    G +  S   +P+PPA+       SP A P 
Sbjct: 969  TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028

Query: 366  SSSRQRPSSTGPPLPPASPSAT 387
                  P +  PP P  SP+AT
Sbjct: 1029 PKGASTPPAATPPSPKGSPAAT 1050



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 10/137 (7%)

Query: 272  YESSPAP---TPSFWSSVPVMGPSLASPSRAASQLAVPS-TPLSPHSAASGTAAGSQPSS 327
            ++ +P P   TP      P   P   +P+  A+    P  +P +P    + T     P S
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342

Query: 328  PRYRP-YTVTHPWASSGVSILSSS--PSPPALASSPQAVPA---SSSRQRPSSTGPPLPP 381
            P+  P    T P +  G +  SS   P+PPA   S +  PA    S ++ P+   P   P
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402

Query: 382  ASPSATSRRPSSLRISP 398
             SP+     P     +P
Sbjct: 1403 TSPAVIPLSPKKAPATP 1419



 Score = 37.4 bits (85), Expect = 0.094
 Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 20/163 (12%)

Query: 247  TGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVP 306
            T  +  TSP  C   S    S   L   +PAP       +PV   S +  ++       P
Sbjct: 1706 TKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL------LPVQKDS-SKTAKGKDASHSP 1758

Query: 307  STPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPP-ALASSPQAVPA 365
              PL+P  + + T     P +       +  P ++S    +S++PSPP +L  +P  VP 
Sbjct: 1759 KGPLAPPESKAST-----PLTAAAFEKVLPKPESAS----VSAAPSPPVSLPLAPSPVPT 1809

Query: 366  SSSRQR--PSSTGPPL-PPASPSATSRRPSSLRISPSLGASGG 405
               +Q+  PSS G  L  P+ P A +     L + P    SGG
Sbjct: 1810 LPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGG 1852



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 38/135 (28%), Positives = 56/135 (41%), Gaps = 26/135 (19%)

Query: 277  APTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGT----AAGSQPS----SP 328
            APTP   +     G   A+P    +     +TP SP  + + T     A + P+    SP
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067

Query: 329  RYRPYTVTHPWASSGVSILSSSPSPPALA-SSPQAVPASSSRQRPSSTGPPLPPASPSAT 387
            +  P T +          L  +P+PPA    SP+  PA+     PS  G P+PPA+   +
Sbjct: 1068 KGGPATPS----------LKGAPTPPAATPPSPKGGPAT-----PSPKGAPMPPAATPPS 1112

Query: 388  SRRPSSLRISPSLGA 402
             +    L   P  GA
Sbjct: 1113 PK--GGLATPPHKGA 1125



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 36/138 (26%), Positives = 55/138 (39%), Gaps = 25/138 (18%)

Query: 274  SSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPY 333
            ++PA TP      P     LA+PS   +     +TP SP    +  +    P++P   P 
Sbjct: 1173 TTPAATP------PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP- 1225

Query: 334  TVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPL---PPASPSATSRR 390
                P    G++    +PSP    ++P A P       PS  G P    P  +P+  +  
Sbjct: 1226 ----PSPKGGLA----TPSPKGAPTTPAATP-------PSPKGGPATPPPKGAPTPPAAT 1270

Query: 391  PSSLRISPSLGASGGASN 408
            P SL+   +     GA N
Sbjct: 1271 PPSLKGGLATPPHKGAPN 1288



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 45/170 (26%), Positives = 73/170 (42%), Gaps = 20/170 (11%)

Query: 227  ATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSV 286
            ATS P    A +P      +   +PGT P        GA +  ++   SP  TP+  ++ 
Sbjct: 1302 ATSPP--KGAPTPPAATPPSPKGSPGTPP------PKGAPTPPAVTPPSPKGTPTLPATT 1353

Query: 287  PVM--GPSLAS-------PSRAASQLAVPS-TPLSPHSAASGTAAGSQPSSPRYRPYTVT 336
            P    GP+  S       P+   S    P+ TP SP    +  +    P+SP   P +  
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413

Query: 337  HPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSA 386
               A+      +++PS   L  +P AV   S ++ P+++ P   PA+PS+
Sbjct: 1414 KAPATPVTREGAATPSKGDL--TPPAVTPVSLKKAPATSAPKGGPATPSS 1461



 Score = 35.0 bits (79), Expect = 0.47
 Identities = 51/186 (27%), Positives = 72/186 (38%), Gaps = 19/186 (10%)

Query: 220  NPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPT 279
            +P  S  AT  P    A +P      +   +P  +P+     +  A++L S  +  PA T
Sbjct: 1018 SPKGSPAAT--PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP-KGGPA-T 1073

Query: 280  PSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPW 339
            PS     P   P  A+P    S    P+TP SP  A    AA   P SP+    T  H  
Sbjct: 1074 PSL-KGAPT--PPAATPP---SPKGGPATP-SPKGAPMPPAA--TPPSPKGGLATPPHKG 1124

Query: 340  ASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTG------PPLPPASPSATSRRPSS 393
            A +  +    SP        P+  P + +   PS  G      P   P +P+AT   P  
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184

Query: 394  LRISPS 399
               +PS
Sbjct: 1185 GLATPS 1190



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 32/137 (23%), Positives = 52/137 (37%), Gaps = 4/137 (2%)

Query: 274  SSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLS-PHSAASGTAAGSQPSSPRYRP 332
            ++PA TP          P   +P+  A+    P   L+ P    + T   + P SP+   
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186

Query: 333  YTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTG---PPLPPASPSATSR 389
             T +   A +  +    SP       SP+  P + +   PS  G    P P  +P+  + 
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246

Query: 390  RPSSLRISPSLGASGGA 406
             P S +  P+     GA
Sbjct: 1247 TPPSPKGGPATPPPKGA 1263



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 41/187 (21%), Positives = 62/187 (33%), Gaps = 7/187 (3%)

Query: 213  STQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLY 272
            +T    +   A+ +    P   AA  P     L T S  G      +        L++  
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236

Query: 273  ESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLS------PHSAASGTAAGSQPS 326
                  TP+     P  GP+   P  A +  A     L       PH  A   A  + PS
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS 1296

Query: 327  SPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSA 386
             P+  P T     A +  +    SP        P+  P   +   PS  G P  PA+  +
Sbjct: 1297 -PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355

Query: 387  TSRRPSS 393
            +   P++
Sbjct: 1356 SKGGPTT 1362



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 56/261 (21%), Positives = 100/261 (38%), Gaps = 28/261 (10%)

Query: 251 PGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPL 310
           P   P     +  G +S +S+ ++     P   S+ P++  SL +P+ AA  L       
Sbjct: 600 PIGKPASSMTSPLGVNSSASVIKTDSYAGPD--SAGPLLKSSLITPTVAAFPLESADPAG 657

Query: 311 SPHSAASGTAAGSQPSSPRYRPYTVT-----HPWASSGVSILSSSPSPP---ALASSPQ- 361
              + A GT+  +  +SP +   TV+     HP     ++ L   P+      +A SPQ 
Sbjct: 658 VAPTTAKGTSTYTTTASP-FLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQN 716

Query: 362 -AVPASSSRQRP----SSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSDHF 416
              P ++    P    S   P LPPA     +++   +  + +L     +       D  
Sbjct: 717 TCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSG 776

Query: 417 TIETCKETDMLNYLIECFDRVGI----EEKKAP--KMCSQP-----AVSQLLSNIRSQCI 465
              T      L YL +    +G+    + K+ P  K  + P      +S  +S + +  +
Sbjct: 777 ASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL 836

Query: 466 SHTALVLQGSLTQPRSLQQPS 486
              +L  QGS   P +   P+
Sbjct: 837 PENSLSFQGSKDSPATTHSPT 857


>gi|24430146 nucleoporin 153kDa [Homo sapiens]
          Length = 1475

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 55/195 (28%), Positives = 81/195 (41%), Gaps = 16/195 (8%)

Query: 222  FASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGAS-SLSSLYESSPAPTP 280
            F S T++S P       P    +    SNP +S  F + A    S SL    +S  A T 
Sbjct: 1212 FGSSTSSSNP-------PVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTS 1264

Query: 281  SFWSSVP--VMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHP 338
            S  ++V   V GP  +S +   S     +T  S  SA S    G+ PS+P   P    + 
Sbjct: 1265 STGTAVTPFVFGPGASSNNTTTSGFGFGATTTSS-SAGSSFVFGTGPSAPSASPAFGANQ 1323

Query: 339  WASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISP 398
              + G S  +S P+PP   S      +SS+   P+ + P  P     ++S +P      P
Sbjct: 1324 TPTFGQSQGASQPNPPGFGSI-----SSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQP 1378

Query: 399  SLGASGGASNWDSYS 413
            S  A G  +  +S S
Sbjct: 1379 SQSAFGSGTTPNSSS 1393


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 49/137 (35%), Positives = 57/137 (41%), Gaps = 7/137 (5%)

Query: 274 SSPAPTPSFWSSVPVMGPSLASPSRAASQLAVP-STPLSPHSAASGTAAGSQPSSPRYRP 332
           S PA  P   S+ P   PS A PS AA  L VP S P SP  + S T     P      P
Sbjct: 678 SPPASPPVSPSATP---PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734

Query: 333 YTVT-HPWASSGVSILSSSPS--PPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSR 389
             V   P AS  +S  ++ P   PP LA+ P  VP S     P S     PP +P A + 
Sbjct: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794

Query: 390 RPSSLRISPSLGASGGA 406
            P     SP     G A
Sbjct: 795 PPLQALPSPPASFPGQA 811



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 56/202 (27%), Positives = 83/202 (41%), Gaps = 33/202 (16%)

Query: 223 ASLTATSQPIAAAARSPDR--------NLLLNTGSNPGTSPMFCSVASFGASSLSSLYES 274
           AS  +T++P  AA R P          +  L++ + P +SP     ++ G     + + S
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA-HPS 270

Query: 275 SPAP-----------TPSFWSSVPVMGPSLASPSRAASQLAVPSTPL-SPHSAASGTAAG 322
            P P           TP    + P +GP  +SP    S     + P+  P +AA+   A 
Sbjct: 271 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT 330

Query: 323 SQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPL--P 380
             PS P   P  +  P  S+  S L + PSPP  A+ P   P       PS T PP+  P
Sbjct: 331 LPPSPPLATPLPLAPPSPSAPPS-LQTLPSPP--ATPPSQAP-------PSMTTPPMQAP 380

Query: 381 PASPSATSRRPSSLRISPSLGA 402
           P+  +    +      SPSL A
Sbjct: 381 PSLQTIPPIQVPHSLTSPSLQA 402



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 59/216 (27%), Positives = 82/216 (37%), Gaps = 38/216 (17%)

Query: 221 PFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFC--SVASFGASSLSSLYESSPAP 278
           P  +L + + P    A +P     L T   P   P+    S  +       S   + P  
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593

Query: 279 TPSFWSSVPVMG-------PSLASPSRAASQLAVP----------STPLSPHSAASGTAA 321
            P   +S P+ G       P    P +A   LA+P          S PLSP +  S  A 
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653

Query: 322 GS------------QPSSPRYRPYTVTHPWASSGVSILSSSPS--PPALASSPQAVPASS 367
            +             PS P   P++   P AS  VS  ++ PS  PP+LA+ P  VP S 
Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710

Query: 368 SRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGAS 403
               P S     PP +P   +  P  L++ PS  AS
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPP--LQVPPSPPAS 744



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 46/148 (31%), Positives = 64/148 (43%), Gaps = 17/148 (11%)

Query: 250 NPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTP 309
           +P  SP     A+  + +  SL  + P   P    + P M PS   P +A   LA P   
Sbjct: 678 SPPASPPVSPSATPPSQAPPSL-AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736

Query: 310 LSPHSAASGTAAGSQPSSPRYRPYTVTHPW-------ASSGVSILSSSP--SPPALASSP 360
           + P   AS   + S    PR  P     P        AS  +S L+  P  +PPALA+ P
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796

Query: 361 -QAVPASSSRQRPSSTGPPLPPASPSAT 387
            QA+P+      P ++ P   P SPSA+
Sbjct: 797 LQALPS------PPASFPGQAPFSPSAS 818



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 58/195 (29%), Positives = 77/195 (39%), Gaps = 23/195 (11%)

Query: 223 ASLTATSQPIAAAARSPDRNLLLN--------TGSNPGTSPMFCSVASFGASSLSSLYES 274
           ASLT+ S+P +    SP     L+        T  +P  SP+   +      +LSSL   
Sbjct: 439 ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498

Query: 275 SP-APTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPY 333
           SP AP  S          SLA PS      ++ + PL  +  +         S+P   P+
Sbjct: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE-NLPSLAPPPLQTASAPLTTPH 557

Query: 334 TVTHPWASSGVSILSSSP---SPPALASS-----PQAVPASSSRQRPSSTGPPLPPASPS 385
             T P  +        SP    PP   SS     PQA PA +S   P   G P PP SP 
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS---PPLQGLPSPPLSPL 614

Query: 386 AT--SRRPSSLRISP 398
           AT   + P  L + P
Sbjct: 615 ATPPPQAPPXLALPP 629



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 57/193 (29%), Positives = 74/193 (38%), Gaps = 20/193 (10%)

Query: 219 ENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAP 278
           E P +  T   Q   A A  P + L      +P  SP+                ++ P+P
Sbjct: 582 ETPSSIATPPPQAPPALASPPLQGL-----PSPPLSPLATPPPQAPPXLALPPLQAPPSP 636

Query: 279 TPSFWSSVPVMGPSLASPS-RAASQLAVP--STPLSPHSAASGTAAGSQPSSPRYRPYTV 335
             S     P + P LA+PS +A + LAV     P SP  +    A  S P+SP   P   
Sbjct: 637 PAS-----PPLSP-LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690

Query: 336 THPWASSGVSI--LSSSPSPPAL-ASSPQAVP---ASSSRQRPSSTGPPLPPASPSATSR 389
               A   ++   L   PSPPA    SP A P   A      P    PP PPASP  +  
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750

Query: 390 RPSSLRISPSLGA 402
                R+ P L A
Sbjct: 751 ATPPPRVPPLLAA 763



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 53/199 (26%), Positives = 69/199 (34%), Gaps = 31/199 (15%)

Query: 220  NPFASLTATSQPIAAAAR-----SPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYES 274
            +P A+    + P+ AA       SP  +  L     P T     SV+      L+     
Sbjct: 822  SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG---PRLTLALAP 878

Query: 275  SPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYT 334
             P P PS   S  + GP LA  S +A+     STP       SG   G+  S P      
Sbjct: 879  GPPPPPSRSPSSTLSGPDLAGHSSSAT-----STPEELRGYDSGPEGGAAASPPPDAELA 933

Query: 335  VTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPP--------LPPASPSA 386
              HP A       S  P+PP         P       P +TGP              P +
Sbjct: 934  ACHPAA------WSRGPAPPLAFRGAPGAPL----PWPPATGPGSADGLCTIYETEGPES 983

Query: 387  TSRRPSSLRISPSLGASGG 405
             +  P +L   PS G SGG
Sbjct: 984  ATPAPGALDPGPSPGTSGG 1002



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 64/223 (28%), Positives = 85/223 (38%), Gaps = 68/223 (30%)

Query: 235 AARSPDRNLLL------NTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPV 288
           A  +P R+ L        +G  PGT     +  S  A +   L    P P PS     P 
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL----PRPAPSARPRPPT 202

Query: 289 MGP----------SLASPSRAASQ---------------LAVPSTPLSPHSAASGTAAG- 322
            GP          S   PS AA +               L+  +TPLS  + +  +A G 
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262

Query: 323 ----SQPSSPR------YRPYTVTHPW--ASSGVSILSSSP--------------SPPAL 356
               + PS P+       RP  VT P   A+  +  LSSSP               PP  
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDN 322

Query: 357 ASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPS 399
           A++P  +PA+     P +T  PL P SPSA    P SL+  PS
Sbjct: 323 AATP--LPATLPPSPPLATPLPLAPPSPSA----PPSLQTLPS 359



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 50/145 (34%), Positives = 61/145 (42%), Gaps = 29/145 (20%)

Query: 273 ESSPAPTPSFWSSVPV-------MGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQP 325
           ++ P+P  SF    P        M P    P +A   LA P   + P   AS T      
Sbjct: 798 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL----- 852

Query: 326 SSPRYRPYTVTHPWASSGVSI-LSSSPSPPALASSPQAVPASSSRQRPSST--GPPLPPA 382
            +PR RP T     + SG  + L+ +P PP         P S S   PSST  GP L   
Sbjct: 853 QAPR-RPPTPGPDTSVSGPRLTLALAPGPPP--------PPSRS---PSSTLSGPDLAGH 900

Query: 383 SPSATSRRPSSLRISPSLGASGGAS 407
           S SATS  P  LR   S G  GGA+
Sbjct: 901 SSSATS-TPEELRGYDS-GPEGGAA 923



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 69/218 (31%), Positives = 83/218 (38%), Gaps = 53/218 (24%)

Query: 233 AAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSL-SSLYESSPAPTPSFWSSVPVMGP 291
           AA A  P  +  L T S  GT           A+ L ++L  S P  TP     +P+  P
Sbjct: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP-----LPLAPP 346

Query: 292 SLASPSRAASQLAVPSTPLSPHSAA--SGTAAGSQ--PSSPRYRPYTVTHPWASSGVSIL 347
           S   PS   S   +PS P +P S A  S T    Q  PS     P  V H   S     L
Sbjct: 347 S---PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS---L 400

Query: 348 SSSPSPPALAS---------------------SPQAVPAS-SSRQRPSST---GPPL--- 379
            + PSP AL+S                     SP+   AS +S  RP+ST    PPL   
Sbjct: 401 QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460

Query: 380 --PPASP-------SATSRRPSSLRISPSLGASGGASN 408
              PASP        A S   S L I P    S  AS+
Sbjct: 461 LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 46/189 (24%), Positives = 73/189 (38%), Gaps = 34/189 (17%)

Query: 244 LLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQL 303
           +L      G  P+       G +++    ES+P   P+  +      P+   P+    + 
Sbjct: 46  VLGAAGAVGRKPLAERAGGIGGATIP---ESAPRAGPTRSAGTSSRNPASRPPASGRGER 102

Query: 304 AVPSTPLSPHSAAS-GTAAGSQPSSPRYRP-------YTVTHPWA---------SSGVSI 346
           A P+   SP   +S G A+G+    P  +         TV    A         S+G   
Sbjct: 103 APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 162

Query: 347 LSSSPSP----PALASSPQAV--------PASSSRQRPSSTGP--PLPPASPSATSRRPS 392
            +S P+P    PA+A   +A         PA S+R RP + GP   +  AS  +T+    
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222

Query: 393 SLRISPSLG 401
           + R  PS G
Sbjct: 223 AARRRPSAG 231



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 13/93 (13%)

Query: 14  LARLAGGQTSQPTTPLTSPQRENPP--GPPIAASAPGPSQSLGLNVHNMTPATSPIGASG 71
           L R A    S   TPL+SP R  P   G P A + P   +  GL        T P     
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP----- 288

Query: 72  VAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQ 104
              R  ++  +  LSSSP   L T S S ++++
Sbjct: 289 ---RKDAAPALGPLSSSP---LATPSPSGTKAR 315


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 55/192 (28%), Positives = 75/192 (39%), Gaps = 33/192 (17%)

Query: 232  IAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGP 291
            +AAA R+  R   L+     G +P      S+ ASS   L  SSP+ +P+F  S   MGP
Sbjct: 1442 LAAAGRAA-REKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTF--SPGKMGP 1498

Query: 292  SLA--------SPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRY--------RPYTV 335
                       SP+ A+     P  P      A GT    +PS+PR          P+ V
Sbjct: 1499 RATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMV 1558

Query: 336  -------------THPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPA 382
                          H  AS+   + S + + P      Q  P S S+  P   GPP  P 
Sbjct: 1559 ITLASDASSQTRMVHASASTS-PLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPR 1617

Query: 383  SPSATSRRPSSL 394
             PSA +  P +L
Sbjct: 1618 VPSAGADGPLAL 1629



 Score = 37.4 bits (85), Expect = 0.094
 Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 21/133 (15%)

Query: 295  SPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRP-YTVTHPWASSGVSILS--SSP 351
            +P  + +QLA P +  +P S+ S        S  R  P   VT  +A      L   SSP
Sbjct: 1309 TPGTSPTQLAAPVSFSTPTSSDS--------SGGRVIPDVRVTQHFAKETQDPLKLHSSP 1360

Query: 352  SPPALASSPQAVPASSSRQRPSSTG-PPLP---------PASPSATSRRPSSLRISPSLG 401
            + P+ AS    +P S     P++T   P P         PASP+ + R PS    + S G
Sbjct: 1361 ASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYG 1420

Query: 402  ASGGASNWDSYSD 414
             S   +N+ S ++
Sbjct: 1421 HSPTTANYGSQTE 1433



 Score = 35.0 bits (79), Expect = 0.47
 Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 17/141 (12%)

Query: 248  GSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMG------PSLAS------ 295
            GS    SP   +  S+G S  ++ Y S     P   S +   G      P  AS      
Sbjct: 1405 GSERSPSPS-STAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGT 1463

Query: 296  --PSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSP 353
              PSRA S  A  S PLSP S +           PR      T   + +  S +  SP  
Sbjct: 1464 PQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGA 1523

Query: 354  PALASSPQAVPASSSRQRPSS 374
            P    SP     + +  RPS+
Sbjct: 1524 P--TPSPMVAQGTQTPHRPST 1542



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 37/134 (27%), Positives = 51/134 (38%), Gaps = 19/134 (14%)

Query: 270 SLYESSPAPTPSFWSSVPVMGPSLASPSRAASQ-----LAVPSTPLSPHSAASGTAAGSQ 324
           SL E +P P P+     PV  P  AS +    Q     L  PS PL   ++   T A   
Sbjct: 524 SLGEPTPLPPPTS-QQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPL 582

Query: 325 PS--SPRYRPYTVTHPWASSGVSILSSS----------PSPPALASSPQAVPASSSRQRP 372
           PS  SP+ +P   + P + +  S+              P PP   +   A P   S  R 
Sbjct: 583 PSKASPQAKPLRASEP-SKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRR 641

Query: 373 SSTGPPLPPASPSA 386
           +    P+  A P A
Sbjct: 642 AEPATPVVKAVPEA 655



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 71/296 (23%), Positives = 113/296 (38%), Gaps = 50/296 (16%)

Query: 45   SAPGPSQSLGLNVHNMT-PATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRS 103
            S  G  +      H+ T PA++P   SG +  S SS    S  SSPS     +     R 
Sbjct: 966  SLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDS-DSSPSRRQRLEEAKQQRK 1024

Query: 104  QSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVC 163
                       +  S   +   IE+   +E  R E+  L ++E     EV +++      
Sbjct: 1025 A----------RHRSHGPLLPTIEDSSEEEELREEEELLREQEKMR--EVEQQRIRSTAR 1072

Query: 164  KIFRV-----SWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRD 218
            K  R      + + R+R     S+LS      P E  S  ++L     ME L  S+ + +
Sbjct: 1073 KTRRDKEELRAQRRRERSKTPPSNLS------PIEDASPTEELRQAAEMEELHRSSCS-E 1125

Query: 219  ENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAP 278
             +P  SL + ++ +                 + G S ++ S + +   +  SLY  SP  
Sbjct: 1126 YSPSPSLDSEAEAL-----------------DGGPSRLYKSGSEYNLPTFMSLY--SPTE 1166

Query: 279  TPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAG-----SQPSSPR 329
            TPS  S+ P  G  L S   A  ++   +  L      +  A G     SQP+ PR
Sbjct: 1167 TPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPR 1222



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 32/126 (25%), Positives = 50/126 (39%), Gaps = 12/126 (9%)

Query: 16  RLAGGQTSQPTTPLTSPQRENPP-GPPIAASAPGP-----SQSLGLNVHNMTPATSPIGA 69
           RL  G   +P TPL  P  + PP G P  AS   P      Q LG     +    SP+  
Sbjct: 519 RLLEGSLGEP-TPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLST 577

Query: 70  SGVAHRSQSSEGVSSL-----SSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDS 124
                 S++S     L     S +PS+  E +++  ++++ M         + +   V S
Sbjct: 578 KASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKS 637

Query: 125 GIENME 130
           G+   E
Sbjct: 638 GVRRAE 643



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 4/57 (7%)

Query: 21   QTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQ 77
            Q SQPTT  ++P    P G P     PGPS + G        A    G+ G A   Q
Sbjct: 3801 QQSQPTTRGSAPAASQPAGKP----QPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQ 3853


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 89/401 (22%), Positives = 153/401 (38%), Gaps = 37/401 (9%)

Query: 21  QTSQPTTPLTSPQRENPPG-PPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSS 79
           +T    +P  +P R +P G PP A+ +  PS +L +        T  +  + +  +  S+
Sbjct: 213 RTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLT-KMDST 271

Query: 80  EGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDEND---- 135
             ++   S PS +  T + S + S SM     S  + + +      +    + + D    
Sbjct: 272 ASITRTPSRPSTASPTGTPSRA-SLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTAS 330

Query: 136 --RREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVS--WKDRDRDVIFLSSLSAQFKQNP 191
             R   R+   + PS      +           R S         +  LSS ++     P
Sbjct: 331 ISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPP 390

Query: 192 KEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNP 251
           +   +                 T          + +T+ P     R+P R     TG+ P
Sbjct: 391 RASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASP----TRTPPR--ASPTGTPP 444

Query: 252 GTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTP-- 309
             SP   +     AS   +   +SP  +PS  ++ P   PS ASP+ + S+ ++  TP  
Sbjct: 445 RASP---TGTPSRASPTGTQSTASPTGSPS--TASPTGSPSTASPTGSPSRASLTRTPSR 499

Query: 310 ---LSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPAS 366
                  S AS T   S+ +SP + P T + P  S   ++   SPS  AL  +P     +
Sbjct: 500 ASLTKMESTASITRTPSR-ASPTWTPSTAS-PTGSPSTALAMGSPSRAALTRTPSRASLT 557

Query: 367 SSRQRPSSTGPPLPPASPSATSRRPSSL---RISPSLGASG 404
            +  R S T P     S ++ +R PS++   R+ PS   +G
Sbjct: 558 RTPSRASLTTP-----SRASLTRTPSTVLLTRMPPSASPTG 593



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 81/373 (21%), Positives = 124/373 (33%), Gaps = 53/373 (14%)

Query: 22  TSQPTT--PLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSS 79
           T +P+T  P  +P R +P G P  AS  G S +         P  SP G    A  ++  
Sbjct: 350 TGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPT--GTPPRASPTGTPSTASLTRKP 407

Query: 80  EGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREK 139
              S        S+     + S +++      +     +         +    ++     
Sbjct: 408 PRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPT 467

Query: 140 RSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFK 199
            S S   P+  P  +          + R       R  +     +A   + P      + 
Sbjct: 468 GSPSTASPTGSPSTASPTGSPSRASLTRTP----SRASLTKMESTASITRTPSRASPTWT 523

Query: 200 DLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCS 259
                        ST +   +P  +L   S   AA  R+P R  L  T S          
Sbjct: 524 P------------STASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSR--------- 562

Query: 260 VASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGT 319
                 +SL++   +S   TPS  + +    P  ASP+   S+ +    P S       +
Sbjct: 563 ------ASLTTPSRASLTRTPS--TVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDS 614

Query: 320 AAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPL 379
            A    + PR  P T T P A       S + +PP   +SP   P      R S TG P 
Sbjct: 615 TASITRTPPRASP-TETPPRA-------SPTGTPP--RASPTGTP-----PRASPTGTP- 658

Query: 380 PPASPSATSRRPS 392
           P ASP+ T  R S
Sbjct: 659 PRASPTGTPSRAS 671



 Score = 35.0 bits (79), Expect = 0.47
 Identities = 39/146 (26%), Positives = 58/146 (39%), Gaps = 30/146 (20%)

Query: 287 PVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWAS----- 341
           P   PS ASP+R  S  ++  TP S  S     +  S   +P     T T P AS     
Sbjct: 4   PTRTPSRASPTRTPSTASLTGTP-SRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTT 62

Query: 342 -----------------SGVSILSSSPS------PPALASSPQAVPASSSRQRPSSTGPP 378
                               S+L+ +PS       P  AS  + +P +S  +RPS+    
Sbjct: 63  SMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLT 122

Query: 379 LPPASPS-ATSRRPSSLRISPSLGAS 403
             P+  S  T+   +SL ++PS  A+
Sbjct: 123 RSPSRASLTTTPSRASLSMTPSTAAA 148



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 44/180 (24%), Positives = 71/180 (39%), Gaps = 21/180 (11%)

Query: 223 ASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLS---SLYESSPAPT 279
           +SL   +  +A+  R P R       S   T P    +     +SL+   S    +  P+
Sbjct: 82  SSLLTRTPSMASLKRMPPR------ASRTRTLPRASLMRRPSTASLTRSPSRASLTTTPS 135

Query: 280 PSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPW 339
            +  S  P    +L  PSRA+    +  TP       + + A    + PR  P  +    
Sbjct: 136 RASLSMTPSTAAALTMPSRAS----LTRTPPRASLTMTPSTASLTRTPPRASPTGMPSRT 191

Query: 340 ASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPS 399
           + +G+      PS  +L         + +  R S TG P P ASP+ +  R +SL + PS
Sbjct: 192 SPTGM------PSTASLTKMDSTASITRTLSRASPTGTP-PRASPTGSPPR-ASLSMMPS 243


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 63/225 (28%), Positives = 93/225 (41%), Gaps = 21/225 (9%)

Query: 214  TQTRDENPFASLTATSQPIAAAARSPDRNLL--LNTGSNPGTSPMFCSVASFGASSL--S 269
            T T +  P  + T T  P+A    +    L     T S P  S  F S     A+S   +
Sbjct: 1933 TSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTT 1992

Query: 270  SLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPS---TPLSPHSAASGT------- 319
            + Y +   P  +  + VP    SL +PS     +   +   T  S HS  +GT       
Sbjct: 1993 TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTL 2052

Query: 320  -AAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPP 378
             A GS  ++P   P TVT    S   S  S++ +  +  SS   +P +SS + PSS    
Sbjct: 2053 KATGSTHTAP---PMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT 2109

Query: 379  LPPASPSATSRRPSSLRISPSLGASGGA-SNWDSY--SDHFTIET 420
              P   SAT+   ++ ++S S   S  A S   SY  S H + +T
Sbjct: 2110 QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQT 2154



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 56/210 (26%), Positives = 83/210 (39%), Gaps = 30/210 (14%)

Query: 213  STQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNP-----------GTSPMFCSVA 261
            ST   +  P ++ T T  P +   R+P  +    T S P           G+SP F S  
Sbjct: 1531 STHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSP-FSSTG 1589

Query: 262  SFGASSL--SSLYESSPAPTPSFWSSVPVMGPSLASPSR---AASQLAVPSTPLSPHSAA 316
               A+S   ++ Y +   P  +  + VP    SL +PS         A  +T  S HS  
Sbjct: 1590 PMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMP 1649

Query: 317  SGT--------AAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSS 368
            +GT        A GS  ++P     T     A S ++   +S S  +  SS     A+S+
Sbjct: 1650 TGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATST 1709

Query: 369  -----RQRPSSTGPPLPPASPSATSRRPSS 393
                    P+STG P    + S TS+  SS
Sbjct: 1710 STTNITPNPTSTGTPPMTVTTSGTSQSRSS 1739



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 54/237 (22%), Positives = 91/237 (38%), Gaps = 37/237 (15%)

Query: 211  MMSTQTRDENPFASLTATSQPIAAAARSPDRN-----LLLNTGSNPGTSPMFCSVASFGA 265
            + ST T+     A+  AT+   + A  S  ++     + L T +  GTSP      +   
Sbjct: 1292 LRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQEL 1351

Query: 266  SSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPST----------PLSPHSA 315
               ++   + P PTP+        GP+   P +     A  +T          P +PH+ 
Sbjct: 1352 PGTTATQTTGPRPTPA-----STTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTT 1406

Query: 316  ASGTAAGSQ-----PSSPRYRPYTVTHPWASSGVSILSS----------SPSPPALASSP 360
             S   AGS      P +      T T+P  S   + L +          +PS   + +  
Sbjct: 1407 HSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPT 1466

Query: 361  QAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSDHFT 417
             A  A+S+    + TG   PP +  AT    ++  I+P+   SG +    S+S + T
Sbjct: 1467 HAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPT--TSGTSQAHSSFSTNKT 1521



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 47/176 (26%), Positives = 75/176 (42%), Gaps = 26/176 (14%)

Query: 239  PDRNLLLNTGSNP-------GTSPMFCSVASFGASSLSSLYESSPAPTP----SFWSSVP 287
            P    L  TGS P       GTS     ++S G S  S+   +SP  TP    +  SS P
Sbjct: 1205 PTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKP 1264

Query: 288  VMG------PSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWAS 341
                     P+ A   +A S L   +T  S  +  + T A ++ ++    P T +   A 
Sbjct: 1265 TASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTS--TAQ 1322

Query: 342  SGVSILSSSPSPPALASSPQAVPASSSRQRP-----SSTGP-PLPPASPSATSRRP 391
            S      + P+P    +SP  +P S++++ P      +TGP P P ++   T+ +P
Sbjct: 1323 STTRTTMTLPTPATSGTSP-TLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQP 1377



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 43/165 (26%), Positives = 67/165 (40%), Gaps = 30/165 (18%)

Query: 260  VASFGASSLSSLYESSPAPTPSFWSS-----VPVMGPSLASPSR---AASQLAVPSTPLS 311
            V S G  + +S + ++  PTPS   +     VP    SL +PS         A  +T  S
Sbjct: 1416 VPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSAS 1475

Query: 312  PHSAASGT--------AAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAV 363
             HSA +GT        A GS  ++P   P T T    S   S  S++ +P +L S     
Sbjct: 1476 NHSAPTGTIPPPTTLKATGSTHTAP---PITPTTSGTSQAHSSFSTNKTPTSLHSHTS-- 1530

Query: 364  PASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASN 408
                     S+  P + P S +  +  P+S R    +  +  A++
Sbjct: 1531 ---------STHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS 1566



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 50/204 (24%), Positives = 72/204 (35%), Gaps = 37/204 (18%)

Query: 208  EVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASS 267
            EV   ST T   NP ++ T T      +A S        T S P  S  F S     A+S
Sbjct: 1536 EVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATS 1595

Query: 268  L--SSLYESSPAPTPSFWSSVPVMGPSLASPSR---AASQLAVPSTPLSPHSAASGT--- 319
               ++ Y +   P  +  + VP    SL +PS         A  +T  S HS  +GT   
Sbjct: 1596 FKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPP 1655

Query: 320  -----AAGSQPSSPRYRPYTV------------------------THPWASSGVSILSSS 350
                 A GS  ++P     T                         TH   ++  S  + +
Sbjct: 1656 PTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNIT 1715

Query: 351  PSPPALASSPQAVPASSSRQRPSS 374
            P+P +  + P  V  S + Q  SS
Sbjct: 1716 PNPTSTGTPPMTVTTSGTSQSRSS 1739



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 5/69 (7%)

Query: 17   LAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRS 76
            L  G T  PT+P+T+    +P GP ++ +    + SL    H  TPA++P+ + G    +
Sbjct: 2288 LTSGVTGIPTSPVTNLTTRHP-GPTLSPTTRFLTSSL--TAHGSTPASAPVSSLGTP--T 2342

Query: 77   QSSEGVSSL 85
             +S GV S+
Sbjct: 2343 PTSPGVCSV 2351


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 81/376 (21%), Positives = 154/376 (40%), Gaps = 60/376 (15%)

Query: 30   TSPQRENPPGPPIAASAPGP-----SQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSS 84
            + P+ E   GPP  +   GP     + + G+++ N + A    G      +  S +    
Sbjct: 1568 SGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGK 1627

Query: 85   LSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDEND--------R 136
                P    +   + +      D++  +    +      + IE+ + + ND        +
Sbjct: 1628 KREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSK 1687

Query: 137  REKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFS 196
            ++++ L D+E        EEQ +Q+        W  ++ +    S  S    +  K+  +
Sbjct: 1688 KQQKRLQDEERRK----KEEQVIQV--------WNKKNANEKGRSQTSKLPPRFAKKQAT 1735

Query: 197  DFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPM 256
              +                       A  +A+  P+A+A   P  +  +   ++   +P+
Sbjct: 1736 GIQQ----------------------AQSSASVPPLASAPLPPSTSASVPASTS---APL 1770

Query: 257  FCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAA 316
              ++    AS+ + +  S+ AP  +  +S PV    LA  S +AS  A  S P S  SAA
Sbjct: 1771 PATLTPVPASTSAPVPASTLAPVLAS-TSAPVPASPLAPVSASASVSA--SVPAST-SAA 1826

Query: 317  SGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSP---PALASS--PQAVPASSSRQR 371
            + T++ +  S+P   P   +    +S V+IL+S+  P    ALAS+  P   PA+SS   
Sbjct: 1827 AITSSSAPASAPAPTPILASVSTPAS-VTILASASIPILASALASTSAPTPAPAASSPAA 1885

Query: 372  PSSTGPPLPPASPSAT 387
            P  T P +P ++P+A+
Sbjct: 1886 PVITAPTIPASAPTAS 1901



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 10/135 (7%)

Query: 274  SSPAPTPSFWSSVPVMG----PSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPR 329
            S+P P PS  +SVP       P+  +P  A++   VP++ L+P  A++     + P +P 
Sbjct: 1751 SAPLP-PSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPV 1809

Query: 330  YRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQR-----PSSTGPPLPPASP 384
                +V+    +S  +   +S S PA A +P  + AS S         S++ P L  A  
Sbjct: 1810 SASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALA 1869

Query: 385  SATSRRPSSLRISPS 399
            S ++  P+    SP+
Sbjct: 1870 STSAPTPAPAASSPA 1884



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 37/121 (30%), Positives = 58/121 (47%), Gaps = 11/121 (9%)

Query: 284  SSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSG 343
            +SVP +  +   PS +AS  A  S PL     A+ T   +  S+P   P +   P  +S 
Sbjct: 1744 ASVPPLASAPLPPSTSASVPASTSAPL----PATLTPVPASTSAP--VPASTLAPVLAST 1797

Query: 344  VSILSSSPSPP--ALASSPQAVPASSSRQRPSSTGPPLPPASPS---ATSRRPSSLRISP 398
             + + +SP  P  A AS   +VPAS+S    +S+  P    +P+   A+   P+S+ I  
Sbjct: 1798 SAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILA 1857

Query: 399  S 399
            S
Sbjct: 1858 S 1858



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 10/100 (10%)

Query: 298  RAASQLAVP---STPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPP 354
            +A S  +VP   S PL P ++AS  A+ S P      P T+T   AS+   + +S+ +P 
Sbjct: 1739 QAQSSASVPPLASAPLPPSTSASVPASTSAPL-----PATLTPVPASTSAPVPASTLAP- 1792

Query: 355  ALASSPQAVPASSSRQRPSSTGPPLP-PASPSATSRRPSS 393
             LAS+   VPAS      +S       PAS SA +   SS
Sbjct: 1793 VLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSS 1832



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 15/80 (18%)

Query: 340  ASSGVSILSSSPSPPALASSPQAVPASSSRQR-------PSSTGPPLP-----PASPSAT 387
            +S+ V  L+S+P PP+ ++S   VPAS+S          P+ST  P+P     P   S +
Sbjct: 1742 SSASVPPLASAPLPPSTSAS---VPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTS 1798

Query: 388  SRRPSSLRISPSLGASGGAS 407
            +  P+S     S  AS  AS
Sbjct: 1799 APVPASPLAPVSASASVSAS 1818


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 48/147 (32%), Positives = 65/147 (44%), Gaps = 17/147 (11%)

Query: 274 SSPAPTPSFWSSVPVMGPSLASPS-RAASQLAVPSTPLSPHSAASG--TAAGSQPSSPRY 330
           ++PAP P+     P   P+LAS + +  ++  VP  P SP    S   TAA  +  + R 
Sbjct: 509 TTPAPAPA---PAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRT 565

Query: 331 ------RPYTVTHPWASSGVSILSSSPSPPALAS--SPQAVPAS--SSRQRPSSTGPPLP 380
                 RP T+  P  S   S   + P PP   S  +PQA+P     S  R  +  PPLP
Sbjct: 566 KRPAPARP-TMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLP 624

Query: 381 PASPSATSRRPSSLRISPSLGASGGAS 407
           P  P    R+      SPS  + G AS
Sbjct: 625 PTPPQPARRQSRRSPASPSPASPGPAS 651



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 18/118 (15%)

Query: 291 PSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSS 350
           P++  P  + S+ + P+ PL P S + GT        P+  P  +         S L + 
Sbjct: 573 PTMPPPQVSGSRSSPPAPPLPPGSGSPGT--------PQALPRRLVG-------SSLRAP 617

Query: 351 PSPPALASSPQAVPASSSRQRPSSTGPPLP-PASPSATS-RRPSSLRISPSLGASGGA 406
             PP L  +P       SR+ P+S  P  P PASPS  S   P+ + +  +  A GGA
Sbjct: 618 TVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAAT-AEGGA 674



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 29/112 (25%), Positives = 42/112 (37%), Gaps = 12/112 (10%)

Query: 12  RRLARLAGGQTSQPTTPLTSPQRENPPGPPI--AASAPGPSQSL-------GLNVHNMTP 62
           RR  R A  + + P  P  S  R +PP PP+   + +PG  Q+L        L    + P
Sbjct: 563 RRTKRPAPARPTMPP-PQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPP 621

Query: 63  ATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCE 114
              P        R QS    +S S +          SLS    +D+   + E
Sbjct: 622 PLPPTPPQPA--RRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAE 671


>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
          Length = 743

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 41/146 (28%), Positives = 65/146 (44%), Gaps = 6/146 (4%)

Query: 262 SFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAA 321
           S G +S S +    P+PT     S+    PSL + S A +    P  PL+  +  + +  
Sbjct: 441 SSGGTSSSPIKAIFPSPT-----SLVATTPSLVTSSAATTLTVSPVLPLTSAAVTNLSVT 495

Query: 322 GSQPSSPRYRPYTV-THPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLP 380
           G+  ++       + T P ASS V+  S SPSP A AS+ +A  AS +    +++ P   
Sbjct: 496 GTSDTTSNNTATVISTAPPASSAVTSPSLSPSPSASASTSEASSASETSTTQTTSTPLSS 555

Query: 381 PASPSATSRRPSSLRISPSLGASGGA 406
           P   S      S L+ + +    G A
Sbjct: 556 PLGTSQVMVTASGLQTAAAAALQGAA 581



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 16/175 (9%)

Query: 214 TQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYE 273
           T     N  A++ +T+ P ++A  SP      +   +P  S    S AS  + + ++   
Sbjct: 497 TSDTTSNNTATVISTAPPASSAVTSP------SLSPSPSASAS-TSEASSASETSTTQTT 549

Query: 274 SSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPY 333
           S+P  +P   S V V    L + + AA Q A    P +   AA   AAG  PS       
Sbjct: 550 STPLSSPLGTSQVMVTASGLQTAAAAALQGAA-QLPANASLAAMAAAAGLNPS------- 601

Query: 334 TVTHPWASSGVSILSSSPSPPALASSPQAVPASS-SRQRPSSTGPPLPPASPSAT 387
            +     ++G ++LS +P   + A SP  +  S+ +  +  ++G  LP  S  AT
Sbjct: 602 LMAPSQFAAGGALLSLNPGTLSGALSPALMSNSTLATIQALASGGSLPITSLDAT 656


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 59/206 (28%), Positives = 85/206 (41%), Gaps = 40/206 (19%)

Query: 219  ENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAP 278
            E P+A+ TAT+  +A     P R  L       G  P    V S G  +        P  
Sbjct: 2124 EGPYAAATATAVSLAQLG-GPGRAGL-------GRQPPGGCVLSLGLLN--------PVA 2167

Query: 279  TPSFWSSVPVM---GPSLASPSRAASQLAVPSTPLSPHS------AASG-----TAAGSQ 324
             P  W+ +P     GPS   P     QL  P TP+SP        A  G      AAG+ 
Sbjct: 2168 VPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGTPVSPQERPPPYLAVPGHGEEYPAAGAH 2227

Query: 325  PSSPRYRPYTVT--HPWASSGVSILS--SSPSPPALA--SSPQAVPASSSRQRPSSTG-- 376
             S P+ R   V   HP+ +         +SPSPP+L+  S     PA+++    ++TG  
Sbjct: 2228 SSPPKARFLRVPSEHPYLTPSPESPEHWASPSPPSLSDWSESTPSPATATGAMATTTGAL 2287

Query: 377  --PPLPPASPSATSRRPSSLRISPSL 400
               PLP + PS+ ++  + L   P +
Sbjct: 2288 PAQPLPLSVPSSLAQAQTQLGPQPEV 2313


>gi|55953110 retinoblastoma protein-binding zinc finger protein
           isoform c [Homo sapiens]
          Length = 1481

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 43/141 (30%), Positives = 63/141 (44%), Gaps = 9/141 (6%)

Query: 276 PAPTPSFWSSVPVMGPSLASPSRAASQLA---VPSTPLSPHSAASGTAAGSQPSSPRYRP 332
           PAPT      V    P+L +PS ++ QL    +P+ P SP          + P  P   P
Sbjct: 733 PAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPP--PPLLP 790

Query: 333 YTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPS 392
            TV  P  SS  S     PSP + A++   +P  S    PS +  P+PP  P  ++  P 
Sbjct: 791 -TVPLPAPSSSASP-HPCPSPLSNATAQSPLPILSPTVSPSPS--PIPPVEPLMSAASPG 846

Query: 393 SLRISPSLGASGGASNWDSYS 413
              +S S  +S  +S++ S S
Sbjct: 847 PPTLSSSSSSSSSSSSFSSSS 867



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 101/422 (23%), Positives = 157/422 (37%), Gaps = 64/422 (15%)

Query: 21  QTSQPTTPLTSPQRENPPGPPIAASAPG---PSQSLGLNVHNMTPATSPIGASGVAHRSQ 77
           QT    TP      E     P+  SAP    P  S        +P +SP  +  +    +
Sbjct: 495 QTQDKLTPAGISATEIAKLGPVCVSAPASMLPVTSSRFKRRTSSPPSSPQHSPALRDFGK 554

Query: 78  SSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRR 137
            S+G ++ + +   S +++ +S S S +  + G    +++S    D     M  +     
Sbjct: 555 PSDGKAAWTDAGLTSKKSKLESHSDSPAWSLSGRDERETVSPPCFDE--YKMSKEWTASS 612

Query: 138 EKRSLSDKEP---SSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEV 194
              S+ +++P   SSG +   E   +       V W+        +  LS   K      
Sbjct: 613 AFSSVCNQQPLDLSSGVKQKAEGTGKTP-----VQWES-------VLDLSVHKKHCSDSE 660

Query: 195 FSDFKDLIGQ---------------ILMEVLMMSTQTRD---ENPFASLTATSQPIAAAA 236
             +FK+                   +L +VL+      D   ENP A  T +  P  +  
Sbjct: 661 GKEFKESHSVQPTCSAVKKRKPTTCMLQKVLLNEYNGIDLPVENP-ADGTRSPSPCKSLE 719

Query: 237 RSPDRNLLLNTG-------SNPGTSPMFCSVASFGASS------LSSLYESSPAPTPSFW 283
             PD +L   +G       S P   P   ++ +   SS      L     SSP P P   
Sbjct: 720 AQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVL 779

Query: 284 SSV---PVMGPS--LASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHP 338
           +     P + P+  L +PS +AS    PS PLS  +A S     S   SP   P     P
Sbjct: 780 TVATPPPPLLPTVPLPAPSSSASPHPCPS-PLSNATAQSPLPILSPTVSPSPSPIPPVEP 838

Query: 339 WASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISP 398
             S+      +SP PP L+SS  +  +SSS    SS+  P PP   + +S   S   +  
Sbjct: 839 LMSA------ASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNLEA 892

Query: 399 SL 400
           SL
Sbjct: 893 SL 894



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 45/163 (27%), Positives = 59/163 (36%), Gaps = 37/163 (22%)

Query: 25  PTTPLTSPQRENPPGP--------------PIAASAPGPSQSLGLNVHNMTPATSP---- 66
           PT PL +P     P P              PI +    PS S    V  +  A SP    
Sbjct: 790 PTVPLPAPSSSASPHPCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEPLMSAASPGPPT 849

Query: 67  IGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGI 126
           + +S  +  S SS   SS SSSPS         LS   S+   G + E S+  +      
Sbjct: 850 LSSSSSSSSSSSSFSSSSSSSSPS------PPPLSAISSVVSSGDNLEASLPMISF---- 899

Query: 127 ENMEVDENDRREKRSLSDKEPSSGPE----VSEEQALQLVCKI 165
              E  EN+  + R    +EP S  E    V E      VC +
Sbjct: 900 -KQEELENEGLKPR----EEPQSAAEQDVVVQETFNKNFVCNV 937


>gi|20336260 retinoblastoma protein-binding zinc finger protein
            isoform b [Homo sapiens]
          Length = 1682

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 43/141 (30%), Positives = 63/141 (44%), Gaps = 9/141 (6%)

Query: 276  PAPTPSFWSSVPVMGPSLASPSRAASQLA---VPSTPLSPHSAASGTAAGSQPSSPRYRP 332
            PAPT      V    P+L +PS ++ QL    +P+ P SP          + P  P   P
Sbjct: 934  PAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPP--PPLLP 991

Query: 333  YTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPS 392
             TV  P  SS  S     PSP + A++   +P  S    PS +  P+PP  P  ++  P 
Sbjct: 992  -TVPLPAPSSSASP-HPCPSPLSNATAQSPLPILSPTVSPSPS--PIPPVEPLMSAASPG 1047

Query: 393  SLRISPSLGASGGASNWDSYS 413
               +S S  +S  +S++ S S
Sbjct: 1048 PPTLSSSSSSSSSSSSFSSSS 1068



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 101/422 (23%), Positives = 157/422 (37%), Gaps = 64/422 (15%)

Query: 21   QTSQPTTPLTSPQRENPPGPPIAASAPG---PSQSLGLNVHNMTPATSPIGASGVAHRSQ 77
            QT    TP      E     P+  SAP    P  S        +P +SP  +  +    +
Sbjct: 696  QTQDKLTPAGISATEIAKLGPVCVSAPASMLPVTSSRFKRRTSSPPSSPQHSPALRDFGK 755

Query: 78   SSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRR 137
             S+G ++ + +   S +++ +S S S +  + G    +++S    D     M  +     
Sbjct: 756  PSDGKAAWTDAGLTSKKSKLESHSDSPAWSLSGRDERETVSPPCFDE--YKMSKEWTASS 813

Query: 138  EKRSLSDKEP---SSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEV 194
               S+ +++P   SSG +   E   +       V W+        +  LS   K      
Sbjct: 814  AFSSVCNQQPLDLSSGVKQKAEGTGKTP-----VQWES-------VLDLSVHKKHCSDSE 861

Query: 195  FSDFKDLIGQ---------------ILMEVLMMSTQTRD---ENPFASLTATSQPIAAAA 236
              +FK+                   +L +VL+      D   ENP A  T +  P  +  
Sbjct: 862  GKEFKESHSVQPTCSAVKKRKPTTCMLQKVLLNEYNGIDLPVENP-ADGTRSPSPCKSLE 920

Query: 237  RSPDRNLLLNTG-------SNPGTSPMFCSVASFGASS------LSSLYESSPAPTPSFW 283
              PD +L   +G       S P   P   ++ +   SS      L     SSP P P   
Sbjct: 921  AQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVL 980

Query: 284  SSV---PVMGPS--LASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHP 338
            +     P + P+  L +PS +AS    PS PLS  +A S     S   SP   P     P
Sbjct: 981  TVATPPPPLLPTVPLPAPSSSASPHPCPS-PLSNATAQSPLPILSPTVSPSPSPIPPVEP 1039

Query: 339  WASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISP 398
              S+      +SP PP L+SS  +  +SSS    SS+  P PP   + +S   S   +  
Sbjct: 1040 LMSA------ASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNLEA 1093

Query: 399  SL 400
            SL
Sbjct: 1094 SL 1095



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 45/163 (27%), Positives = 59/163 (36%), Gaps = 37/163 (22%)

Query: 25   PTTPLTSPQRENPPGP--------------PIAASAPGPSQSLGLNVHNMTPATSP---- 66
            PT PL +P     P P              PI +    PS S    V  +  A SP    
Sbjct: 991  PTVPLPAPSSSASPHPCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEPLMSAASPGPPT 1050

Query: 67   IGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGI 126
            + +S  +  S SS   SS SSSPS         LS   S+   G + E S+  +      
Sbjct: 1051 LSSSSSSSSSSSSFSSSSSSSSPS------PPPLSAISSVVSSGDNLEASLPMISF---- 1100

Query: 127  ENMEVDENDRREKRSLSDKEPSSGPE----VSEEQALQLVCKI 165
               E  EN+  + R    +EP S  E    V E      VC +
Sbjct: 1101 -KQEELENEGLKPR----EEPQSAAEQDVVVQETFNKNFVCNV 1138


>gi|20336258 retinoblastoma protein-binding zinc finger protein
            isoform a [Homo sapiens]
          Length = 1718

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 43/141 (30%), Positives = 63/141 (44%), Gaps = 9/141 (6%)

Query: 276  PAPTPSFWSSVPVMGPSLASPSRAASQLA---VPSTPLSPHSAASGTAAGSQPSSPRYRP 332
            PAPT      V    P+L +PS ++ QL    +P+ P SP          + P  P   P
Sbjct: 934  PAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPP--PPLLP 991

Query: 333  YTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPS 392
             TV  P  SS  S     PSP + A++   +P  S    PS +  P+PP  P  ++  P 
Sbjct: 992  -TVPLPAPSSSASP-HPCPSPLSNATAQSPLPILSPTVSPSPS--PIPPVEPLMSAASPG 1047

Query: 393  SLRISPSLGASGGASNWDSYS 413
               +S S  +S  +S++ S S
Sbjct: 1048 PPTLSSSSSSSSSSSSFSSSS 1068



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 101/422 (23%), Positives = 157/422 (37%), Gaps = 64/422 (15%)

Query: 21   QTSQPTTPLTSPQRENPPGPPIAASAPG---PSQSLGLNVHNMTPATSPIGASGVAHRSQ 77
            QT    TP      E     P+  SAP    P  S        +P +SP  +  +    +
Sbjct: 696  QTQDKLTPAGISATEIAKLGPVCVSAPASMLPVTSSRFKRRTSSPPSSPQHSPALRDFGK 755

Query: 78   SSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRR 137
             S+G ++ + +   S +++ +S S S +  + G    +++S    D     M  +     
Sbjct: 756  PSDGKAAWTDAGLTSKKSKLESHSDSPAWSLSGRDERETVSPPCFDE--YKMSKEWTASS 813

Query: 138  EKRSLSDKEP---SSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEV 194
               S+ +++P   SSG +   E   +       V W+        +  LS   K      
Sbjct: 814  AFSSVCNQQPLDLSSGVKQKAEGTGKTP-----VQWES-------VLDLSVHKKHCSDSE 861

Query: 195  FSDFKDLIGQ---------------ILMEVLMMSTQTRD---ENPFASLTATSQPIAAAA 236
              +FK+                   +L +VL+      D   ENP A  T +  P  +  
Sbjct: 862  GKEFKESHSVQPTCSAVKKRKPTTCMLQKVLLNEYNGIDLPVENP-ADGTRSPSPCKSLE 920

Query: 237  RSPDRNLLLNTG-------SNPGTSPMFCSVASFGASS------LSSLYESSPAPTPSFW 283
              PD +L   +G       S P   P   ++ +   SS      L     SSP P P   
Sbjct: 921  AQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVL 980

Query: 284  SSV---PVMGPS--LASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHP 338
            +     P + P+  L +PS +AS    PS PLS  +A S     S   SP   P     P
Sbjct: 981  TVATPPPPLLPTVPLPAPSSSASPHPCPS-PLSNATAQSPLPILSPTVSPSPSPIPPVEP 1039

Query: 339  WASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISP 398
              S+      +SP PP L+SS  +  +SSS    SS+  P PP   + +S   S   +  
Sbjct: 1040 LMSA------ASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNLEA 1093

Query: 399  SL 400
            SL
Sbjct: 1094 SL 1095



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 45/163 (27%), Positives = 59/163 (36%), Gaps = 37/163 (22%)

Query: 25   PTTPLTSPQRENPPGP--------------PIAASAPGPSQSLGLNVHNMTPATSP---- 66
            PT PL +P     P P              PI +    PS S    V  +  A SP    
Sbjct: 991  PTVPLPAPSSSASPHPCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEPLMSAASPGPPT 1050

Query: 67   IGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGI 126
            + +S  +  S SS   SS SSSPS         LS   S+   G + E S+  +      
Sbjct: 1051 LSSSSSSSSSSSSFSSSSSSSSPS------PPPLSAISSVVSSGDNLEASLPMISF---- 1100

Query: 127  ENMEVDENDRREKRSLSDKEPSSGPE----VSEEQALQLVCKI 165
               E  EN+  + R    +EP S  E    V E      VC +
Sbjct: 1101 -KQEELENEGLKPR----EEPQSAAEQDVVVQETFNKNFVCNV 1138


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 59/221 (26%), Positives = 93/221 (42%), Gaps = 25/221 (11%)

Query: 208 EVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNP-GTSPMFCSVASFGAS 266
           E L  S+   +  P  +  AT+ P+  A+  P      +  S P  T+    ++AS   +
Sbjct: 293 EALRRSSTPIEHAPVCTSQATT-PLLPASAQPPAAASPSAASPPLATAAAHTAIASASTT 351

Query: 267 SLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASG-TAAGSQP 325
           + +S    SP P  S +S      P++A+ S  A+  +    P +P       T A  +P
Sbjct: 352 APASSPADSPRPQASSYS------PAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRP 405

Query: 326 SSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPS 385
           S  +  P +   P   +  S    +PSP A A +P   PA +    P+ T  P P  +PS
Sbjct: 406 SVYQPVPASTYSPSPGANYSPTPYTPSP-APAYTPSPAPAYTPSPVPTYTPSPAPAYTPS 464

Query: 386 -ATSRRPSSLRISPSLGASGGASN------W---DSYSDHF 416
            A +  P+     PS+  SGG +       W   DS+S  F
Sbjct: 465 PAPNYNPA-----PSVAYSGGPAEPASRPPWVTDDSFSQKF 500



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 19/80 (23%)

Query: 22  TSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEG 81
           TSQ TTPL  P    PP    AA++P               A SP  A+  AH + +S  
Sbjct: 309 TSQATTPLL-PASAQPP----AAASPS--------------AASPPLATAAAHTAIASAS 349

Query: 82  VSSLSSSPSNSLETQSQSLS 101
            ++ +SSP++S   Q+ S S
Sbjct: 350 TTAPASSPADSPRPQASSYS 369


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 53/225 (23%), Positives = 94/225 (41%), Gaps = 29/225 (12%)

Query: 213  STQTRDENPFASLTATSQPI----AAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSL 268
            STQ     P  S TAT+  +    A  + SP     L    +  T+P   S  +  +SSL
Sbjct: 4474 STQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSL 4533

Query: 269  SSLY---ESSPAPTPSFWSSVPVMGP----------SLASPSRAASQLAVPS-TPLSPHS 314
             + +     +  PT +  ++ P   P          + A+ + A   +A PS TP + H+
Sbjct: 4534 GTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHT 4593

Query: 315  AASGTAAGSQ-PSSPRYRPYTVTHP--WASSGVSILSSSPSPPALASSPQAVPASSSRQR 371
                T   +   ++P   P T   P  W S+  +  +++P+      +P ++P ++   R
Sbjct: 4594 TKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTAR 4653

Query: 372  -------PSSTGPPLPPASPSATSRRPSSL-RISPSLGASGGASN 408
                     +TG    P+S + TS  P SL   + ++ A+G  +N
Sbjct: 4654 VLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTN 4698



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 56/206 (27%), Positives = 85/206 (41%), Gaps = 37/206 (17%)

Query: 225  LTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTP---- 280
            LT T+  +A  + +   +    +G+ P  +    ++ + G+++  S   S+P  TP    
Sbjct: 3365 LTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS---STPGTTPIPPV 3421

Query: 281  -SFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPW 339
             +  ++ P    S  +PS A   L    TP  P++ A+       PSSP    +TV   W
Sbjct: 3422 LTTTATTPAATSSTVTPSSA---LGTTHTPPVPNTTATTHGRSLPPSSP----HTVRTAW 3474

Query: 340  ASSGVSILS----------SSPSPPALASSPQ-AVPASSSRQRPSST--GPPLP----PA 382
             S+   IL           +S +P A  S+ Q + PA SS    S T   PP P    P 
Sbjct: 3475 TSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 3534

Query: 383  SPSATSR-----RPSSLRISPSLGAS 403
                TSR      PS  R S  L +S
Sbjct: 3535 HTRGTSRTTATATPSKTRTSTLLPSS 3560



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 23/203 (11%)

Query: 202  IGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVA 261
            + Q       MST T    P  + T+T    A A  +     +    S PGT+     V 
Sbjct: 1998 LSQTTTPTATMSTATPSSTPETAHTSTVLT-ATATTTGATGSVATPSSTPGTAHT-TKVP 2055

Query: 262  SFGASSLSSLYESSP--APTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGT 319
            +   +  ++   SSP  A TP  W S      +  +P+   S +   S P + H+A   T
Sbjct: 2056 TTTTTGFTATPSSSPGTALTPPVWIS------TTTTPTTRGSTVTPSSIPGTTHTATVLT 2109

Query: 320  AAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSST--GP 377
               +          TV     ++  S   +S +PP+L ++   + A+ S   PSST    
Sbjct: 2110 TTTT----------TVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTT 2159

Query: 378  PLPPA-SPSATSRRPSSLRISPS 399
            P+PP  + +AT+   +S  ++PS
Sbjct: 2160 PIPPVLTTTATTPAATSNTVTPS 2182



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 55/206 (26%), Positives = 84/206 (40%), Gaps = 37/206 (17%)

Query: 225  LTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTP---- 280
            LT T+  +A  + +   +    +G+ P  +    ++ + G+++  S   S+P  TP    
Sbjct: 2665 LTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS---STPGTTPIPPV 2721

Query: 281  -SFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPW 339
             +  ++ P    S  +PS A   L    TP  P++ A+       PSS    P+TV   W
Sbjct: 2722 LTTTATTPAATSSTVTPSSA---LGTTHTPPVPNTTATTHGRSLSPSS----PHTVRTAW 2774

Query: 340  ASSGVSIL----------SSSPSPPALASSPQ-AVPASSSRQRPSST--GPPLP----PA 382
             S+    L           +S +P A   + Q + PA SS    S T   PP P    P 
Sbjct: 2775 TSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 2834

Query: 383  SPSATSR-----RPSSLRISPSLGAS 403
               ATSR      PS  R S  L +S
Sbjct: 2835 HTRATSRTTATATPSKTRTSTLLPSS 2860



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 47/209 (22%), Positives = 88/209 (42%), Gaps = 39/209 (18%)

Query: 213  STQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLY 272
            STQ     P  S TAT+  + ++  +P         S+PGT           A++L +L 
Sbjct: 3746 STQATAGTPHVSTTATTPTVTSSKATPF--------SSPGT-----------ATALPALR 3786

Query: 273  ESSPAPTPSFWSSVPVMG--------PSLASPSRAASQLAVPSTPLSPHS-------AAS 317
             ++  PT + ++++P               +P+   S     STP + H+       A +
Sbjct: 3787 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATT 3846

Query: 318  GTAAGS--QPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSST 375
              A GS   PSS     +T   P  ++    ++ S SP    + P  +  +++   P+++
Sbjct: 3847 TRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTT---PTTS 3903

Query: 376  GPPLPPASPSATSRRPSSLRISPSLGASG 404
            G  + P+S   T+  P+ L  + +  A+G
Sbjct: 3904 GSTVTPSSVPGTTHTPTVLTTTTTTVATG 3932



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 55/206 (26%), Positives = 84/206 (40%), Gaps = 37/206 (17%)

Query: 225  LTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTP---- 280
            LT T+  +A  + +   +    +G+ P       ++ + G+++  S   S+P  TP    
Sbjct: 3922 LTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPS---STPGTTPIPPV 3978

Query: 281  -SFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPW 339
             +  ++ P    S  +PS A   L    TP  P++ A+       PSS    P+TV   W
Sbjct: 3979 LTTTATTPAATSSTVTPSSA---LGTTHTPPVPNTTATTHGRSLSPSS----PHTVRTAW 4031

Query: 340  ASSGVSIL----------SSSPSPPALASSPQ-AVPASSSRQRPSST--GPPLP----PA 382
             S+    L           +S +P A   + Q + PA SS    S T   PP P    P 
Sbjct: 4032 TSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 4091

Query: 383  SPSATSR-----RPSSLRISPSLGAS 403
              +ATSR      PS  R S  L +S
Sbjct: 4092 HTTATSRTTATATPSKTRTSTLLPSS 4117



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 51/207 (24%), Positives = 85/207 (41%), Gaps = 39/207 (18%)

Query: 225  LTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWS 284
            LT T+  +A  + +   +    +G+ P  +    ++ + G+++       +P+ TP    
Sbjct: 2108 LTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTT-------NPSSTPGTTP 2160

Query: 285  SVPVMGPSLASPSRAA------SQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHP 338
              PV+  +  +P+  +      S L    TP  P++ A+       PSS    P+TV   
Sbjct: 2161 IPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSS----PHTVRTA 2216

Query: 339  W--ASSGV---------SILSSSPSPPALASSPQAVPASSSRQRPSST--GPPLP----P 381
            W  A+SG+         S ++S        ++  + PA SS    S T   PP P    P
Sbjct: 2217 WTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP 2276

Query: 382  ASPSATSR-----RPSSLRISPSLGAS 403
               +ATSR      PS  R S  L +S
Sbjct: 2277 GHTTATSRTTATATPSKTRTSTLLPSS 2303



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 108/491 (21%), Positives = 173/491 (35%), Gaps = 97/491 (19%)

Query: 12   RRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASA-------PGPSQSLGL-------NV 57
            R  + L    T  PTTP  S +   P  P +A S        PG + SLG         +
Sbjct: 1664 RYTSTLGTATTGGPTTPAGSTE---PTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTL 1720

Query: 58   HNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSM 117
               T ATS    +G A  +      +SL+ + ++ L T     S  ++          + 
Sbjct: 1721 APTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTT 1780

Query: 118  SQ--------------VDVD---SGIE--NMEVDENDRREKRSLS------DKEPSSGPE 152
            SQ               DVD   SG+   +ME  EN R     +       +    + PE
Sbjct: 1781 SQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPE 1840

Query: 153  VSEEQALQ-LVCKIFR-VSWKDRDRDVIFLSSLSAQ--------FKQNPKEVFSDFKDLI 202
            VS +Q  Q L C +   ++ K+ D+   F    +          +   P    +      
Sbjct: 1841 VSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATP 1900

Query: 203  GQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVAS 262
                    +++  T      AS  +T+ P +    +P   +L  T + P  +    + +S
Sbjct: 1901 SSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSS 1960

Query: 263  FGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVP----------STPLSP 312
               ++ +     S A TP+  S  P+   SL +     SQ   P          STP + 
Sbjct: 1961 SPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETA 2020

Query: 313  HSA----ASGTAAGSQ-----PSSPRYRPYTVTHPWASSG--VSILSSSP----SPPALA 357
            H++    A+ T  G+      PSS     +T   P  ++    +  SSSP    +PP   
Sbjct: 2021 HTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWI 2080

Query: 358  SSPQAVPASSSRQRPSS-------------------TGPPLPPASPSATSRRPSSL-RIS 397
            S+        S   PSS                   TG    P+S + TS  P SL   +
Sbjct: 2081 STTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTA 2140

Query: 398  PSLGASGGASN 408
             ++ A+G  +N
Sbjct: 2141 TTITATGSTTN 2151



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 44/201 (21%), Positives = 84/201 (41%), Gaps = 19/201 (9%)

Query: 202  IGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVA 261
            + Q       MST T    P    T+T     A       ++     S PGT+       
Sbjct: 2555 LSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVA-TPSSTPGTAH-----T 2608

Query: 262  SFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAA 321
            +   ++ ++ + ++P+ +P    ++PV   +  +P+   S +   S P + H+    T  
Sbjct: 2609 TKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTT 2668

Query: 322  GSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSST--GPPL 379
             +          TV     ++  S   +S +PP+L ++   + A+ S   PSST    P+
Sbjct: 2669 TT----------TVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPI 2718

Query: 380  PPA-SPSATSRRPSSLRISPS 399
            PP  + +AT+   +S  ++PS
Sbjct: 2719 PPVLTTTATTPAATSSTVTPS 2739



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 49/203 (24%), Positives = 81/203 (39%), Gaps = 23/203 (11%)

Query: 202  IGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVA 261
            + Q       MST T    P    T+T             ++     S PGT+     V 
Sbjct: 3255 LSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVA-TPSSTPGTAHT-TKVP 3312

Query: 262  SFGASSLSSLYESSP--APTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGT 319
            +   +  ++   SSP  A TP  W S      +  +P+   S +   S P + H+A   T
Sbjct: 3313 TTTTTGFTATPSSSPGTALTPPVWIS------TTTTPTTRGSTVTPSSIPGTTHTATVLT 3366

Query: 320  AAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPASSSRQRPSST--GP 377
               +          TV     ++  S   +S +PP+L ++   + A+ S   PSST    
Sbjct: 3367 TTTT----------TVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTT 3416

Query: 378  PLPPA-SPSATSRRPSSLRISPS 399
            P+PP  + +AT+   +S  ++PS
Sbjct: 3417 PIPPVLTTTATTPAATSSTVTPS 3439



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 44/207 (21%), Positives = 85/207 (41%), Gaps = 35/207 (16%)

Query: 213  STQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLY 272
            STQ     P  S TAT+  + ++  +P         S+PGT           A++L +L 
Sbjct: 2489 STQATAGTPHVSTTATTPTVTSSKATPF--------SSPGT-----------ATALPALR 2529

Query: 273  ESSPAPTPSFWSSVPVMG--------PSLASPSRAASQLAVPSTPLSPHSA------ASG 318
             ++  PT + ++++P               +P+   S     STP + H++      A+ 
Sbjct: 2530 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATT 2589

Query: 319  TAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSPQAVPA-SSSRQRPSSTGP 377
            T A    ++P   P T  H       +    + +P +   + + +P   S+   P++ G 
Sbjct: 2590 TGATGSVATPSSTPGTA-HTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGS 2648

Query: 378  PLPPASPSATSRRPSSLRISPSLGASG 404
             + P+S   T+  P+ L  + +  A+G
Sbjct: 2649 TVTPSSIPGTTHTPTVLTTTTTTVATG 2675



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 54/223 (24%), Positives = 85/223 (38%), Gaps = 29/223 (13%)

Query: 202  IGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVA 261
            + Q       MST T    P    T+T    A A  +     +    S PGT+     V 
Sbjct: 4540 LSQTTTPTATMSTATPSSTPETVHTSTVLT-ATATTTGATGSVATPSSTPGTAHT-TKVP 4597

Query: 262  SFGASSLSSLYESSP--APTPSFWSSVPVMGPSLASPSRAASQLAVPSTPLSPHSA---- 315
            +   +  ++   SSP  A TP  W S     P+  +P+ + S +   S P + H+A    
Sbjct: 4598 TTTTTGFTATPSSSPGTALTPPVWISTTTT-PTTTTPTTSGSTVTPSSIPGTTHTARVLT 4656

Query: 316  --------------ASGTAAGSQPSSPRYRPYTVTHPWASSGVSIL-SSSPSPPALASSP 360
                          +S T     P S      T+T   +++  S    ++P  P L S+ 
Sbjct: 4657 TTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTA 4716

Query: 361  QAVPASSSRQRPSSTGP----PLPPASPSATSRRPSSLRISPS 399
               PA++S +  SS+ P     LP  + +AT    +S    PS
Sbjct: 4717 -TTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPS 4758



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 48/207 (23%), Positives = 85/207 (41%), Gaps = 24/207 (11%)

Query: 226  TATSQPI----AAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLY---ESSPAP 278
            TAT+  +    A  + SP     L    +  T+P   SV +  +SSL + +     +  P
Sbjct: 3202 TATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTP 3261

Query: 279  TPSFWSSVPVMGPSLASPS----------RAASQLAVPS-TPLSPHSAASGTAAGSQ-PS 326
            T +  ++ P   P     S          RA   +A PS TP + H+    T   +   +
Sbjct: 3262 TATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTA 3321

Query: 327  SPRYRPYTVTHP--WASSGVSILS--SSPSPPALASSPQAVPASSSRQRPSSTGPPLPPA 382
            +P   P T   P  W S+  +  +  S+ +P ++  +       ++     +TG    P+
Sbjct: 3322 TPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPS 3381

Query: 383  SPSATSRRPSSL-RISPSLGASGGASN 408
            S + TS  P SL   + ++ A+G  +N
Sbjct: 3382 SSTQTSGTPPSLTTTATTITATGSTTN 3408



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 33/191 (17%), Positives = 83/191 (43%), Gaps = 15/191 (7%)

Query: 225  LTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWS 284
            LT T+  +A  + +   +    +G+ P  +    ++ + G+++       +P+ TP    
Sbjct: 4655 LTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTT-------NPSSTPGTTP 4707

Query: 285  SVPVMGPSLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGV 344
              PV+  +  +P+  +S+    S+P +  +    T+  ++ ++  + P   +  W +  V
Sbjct: 4708 ITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTV 4767

Query: 345  SILSSSP----SPPALASSPQAVPAS----SSRQRPSSTGPPLPPASPSATSRRPSSLRI 396
               +++P    S    +S+P+    S    ++     +T     P+S   T+R  + L  
Sbjct: 4768 PAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTT 4827

Query: 397  SPSLGASGGAS 407
            + +  A+ G++
Sbjct: 4828 TATTTAATGST 4838



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 33/120 (27%), Positives = 54/120 (45%), Gaps = 13/120 (10%)

Query: 306  PSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSG-----VSILSSSPSPPALASSP 360
            PSTP +  +A   +  G+  +    +P T     AS+G      S L ++P P  L ++ 
Sbjct: 1889 PSTPATSSTATPSSTPGT--TWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTA 1946

Query: 361  QAVPASSSRQRPSS---TGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSDHFT 417
                 +SS+  PSS   T   LP    +AT+  P++  ++P   +S G + W   S   T
Sbjct: 1947 TTPTVTSSKATPSSSPGTATALPALRSTATT--PTATSVTPIPSSSLG-TTWTRLSQTTT 2003



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 10/108 (9%)

Query: 306  PSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPS---PPALASSPQA 362
            PSTP +  +A   +  G+          T T   ++   +  SS+P    PP + +SP  
Sbjct: 4232 PSTPATSSTAMPSSTPGTTWILTELTT-TATTTASTGSTATPSSTPGTAPPPKVLTSPAT 4290

Query: 363  VPASSSRQRPSSTGP----PLPPASPSATSRRPSSLRISPS--LGASG 404
             P ++S +  SS+ P     LP  + +AT    +S+   PS  LG +G
Sbjct: 4291 TPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTG 4338



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 38/161 (23%), Positives = 67/161 (41%), Gaps = 12/161 (7%)

Query: 223  ASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSF 282
            A+ TA++   A  + +P    +L   S   T     +V +   ++ SS   ++  P  S 
Sbjct: 4431 ATTTASTGSTATPSSTPGTTWILTEPSTTAT----VTVPTGSTATASSTQATAGTPHVST 4486

Query: 283  WSSVPVMGPSLASPS----RAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHP 338
             ++ P +  S A+PS     A +  A+ ST  +P + +      S   +   R    T P
Sbjct: 4487 TATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 4546

Query: 339  WASSGVSILSSSP----SPPALASSPQAVPASSSRQRPSST 375
             A+   +  SS+P    +   L ++     A+ S   PSST
Sbjct: 4547 TATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSST 4587



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 43/192 (22%), Positives = 74/192 (38%), Gaps = 27/192 (14%)

Query: 223  ASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSF 282
            A+ T ++   A  + +P    +L   S   T     +V +   ++ SS   ++  P  S 
Sbjct: 3703 ATTTESTGSTATPSSTPGTTWILTEPSTTAT----VTVPTGSTATASSTQATAGTPHVST 3758

Query: 283  WSSVPVMGPSLA----SPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHP 338
             ++ P +  S A    SP  A +  A+ ST  +P + +      S   +   R    T P
Sbjct: 3759 TATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 3818

Query: 339  WASSGVSILSSSP----SPPALASSPQAVPASSSRQRPSS---------------TGPPL 379
             A+   +  SS+P    +   L ++     A+ S   PSS               TG  +
Sbjct: 3819 TATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTV 3878

Query: 380  PPASPSATSRRP 391
             P+S   T+R P
Sbjct: 3879 TPSSSPGTARTP 3890



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 18/165 (10%)

Query: 245  LNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTP-SFW---------SSVPVMGPSLA 294
            ++  S P T+     + +   ++ ++   S+P+ TP + W         ++    GP+ A
Sbjct: 4354 IHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT-A 4412

Query: 295  SPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPP 354
            +PS       + +   +  +  + T + + PSS     + +T P  ++ V++ + S    
Sbjct: 4413 TPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGS---T 4469

Query: 355  ALASSPQAVP----ASSSRQRPSSTGPPLPPASPSATSRRPSSLR 395
            A ASS QA       S++   P+ T     P+S   T+    +LR
Sbjct: 4470 ATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALR 4514


>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 38/119 (31%), Positives = 58/119 (48%), Gaps = 5/119 (4%)

Query: 292 SLASPSRAASQLAVPSTPLSPHSAASGTAAGSQPSSP--RYRPYTVTHPWASSGVSILSS 349
           S+A         A P  P  P S++S +++ S PS P   + P  +  P A+ G+S L S
Sbjct: 27  SMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGTHNPGGLKPP-ATGGLSSLGS 85

Query: 350 SPSPPALASSPQAVPASSSR-QRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGAS 407
            P   + A++P  +    SR   P ++G  LP ASPS +S   SS   + S  A+  A+
Sbjct: 86  PPQQLS-AATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAA 143



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 46/174 (26%), Positives = 71/174 (40%), Gaps = 25/174 (14%)

Query: 221 PFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTP 280
           P    +++S   ++++ SP     L T +  G  P     A+ G SSL S  +   A TP
Sbjct: 44  PAGPPSSSSSSSSSSSPSPP----LGTHNPGGLKPP----ATGGLSSLGSPPQQLSAATP 95

Query: 281 SFWSSVPVMGPSLASPSR-AASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPW 339
              + +      L+ PS   AS  A+PS   S  S++S ++A +  +S            
Sbjct: 96  HGINDI------LSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAA 149

Query: 340 ASSGVSI---------LSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASP 384
           ASS   +         LS  P PP L  SP A   ++  + P      LP  +P
Sbjct: 150 ASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLA-ELPGRTP 202


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,787,646
Number of Sequences: 37866
Number of extensions: 2583041
Number of successful extensions: 26007
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 1151
Number of HSP's that attempted gapping in prelim test: 18489
Number of HSP's gapped (non-prelim): 7141
length of query: 1302
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1188
effective length of database: 13,930,794
effective search space: 16549783272
effective search space used: 16549783272
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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