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Search of human proteins with 157694489
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157694489 immunoglobulin superfamily, member 2 [Homo
sapiens]
(1021 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens] 2063 0.0
gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo... 629 e-180
gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo... 620 e-177
gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens] 279 8e-75
gi|41152506 prostaglandin F2 receptor negative regulator [Homo s... 227 4e-59
gi|239753216 PREDICTED: similar to immunoglobulin superfamily, m... 194 3e-49
gi|169215606 PREDICTED: similar to immunoglobulin superfamily, m... 173 6e-43
gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens] 173 6e-43
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 56 2e-07
gi|24111244 MAM domain containing glycosylphosphatidylinositol a... 53 2e-06
gi|222144244 fibroblast growth factor receptor 2 isoform 9 precu... 47 7e-05
gi|222144231 fibroblast growth factor receptor 2 isoform 3 precu... 47 7e-05
gi|221316638 fibroblast growth factor receptor 2 isoform 2 precu... 47 7e-05
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 47 9e-05
gi|190341099 hypothetical protein LOC196740 isoform 1 [Homo sapi... 47 1e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 46 2e-04
gi|144226847 obscurin-like 1 [Homo sapiens] 46 2e-04
gi|8393638 F11 receptor precursor [Homo sapiens] 45 3e-04
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 45 3e-04
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 45 3e-04
gi|118572606 hemicentin 1 [Homo sapiens] 44 6e-04
gi|19923629 Fc receptor-like 2 precursor [Homo sapiens] 43 0.001
gi|109150416 peroxidasin [Homo sapiens] 42 0.002
gi|21450677 hypothetical protein LOC196740 isoform 2 [Homo sapiens] 41 0.005
gi|7657361 contactin 6 [Homo sapiens] 40 0.015
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 39 0.019
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 39 0.025
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 39 0.025
gi|139948432 adlican [Homo sapiens] 39 0.025
gi|142976733 surface glycoprotein, Ig superfamily member [Homo s... 39 0.033
>gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens]
Length = 1021
Score = 2063 bits (5345), Expect = 0.0
Identities = 1021/1021 (100%), Positives = 1021/1021 (100%)
Query: 1 MAGISYVASFFLLLTKLSIGQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSV 60
MAGISYVASFFLLLTKLSIGQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSV
Sbjct: 1 MAGISYVASFFLLLTKLSIGQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSV 60
Query: 61 YLPTNPTQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYE 120
YLPTNPTQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYE
Sbjct: 61 YLPTNPTQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYE 120
Query: 121 CHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHL 180
CHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHL
Sbjct: 121 CHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHL 180
Query: 181 SVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQ 240
SVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQ
Sbjct: 181 SVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQ 240
Query: 241 SSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPL 300
SSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPL
Sbjct: 241 SSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPL 300
Query: 301 ELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAF 360
ELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAF
Sbjct: 301 ELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAF 360
Query: 361 SLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNK 420
SLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNK
Sbjct: 361 SLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNK 420
Query: 421 QQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSY 480
QQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSY
Sbjct: 421 QQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSY 480
Query: 481 HGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLESS 540
HGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLESS
Sbjct: 481 HGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLESS 540
Query: 541 LQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGT 600
LQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGT
Sbjct: 541 LQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGT 600
Query: 601 IEWGNFLSRFQKKTKVSQSLFRSQLLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASA 660
IEWGNFLSRFQKKTKVSQSLFRSQLLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASA
Sbjct: 601 IEWGNFLSRFQKKTKVSQSLFRSQLLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASA 660
Query: 661 ISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSILSRSNGNLQLAIIWYFSPVST 720
ISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSILSRSNGNLQLAIIWYFSPVST
Sbjct: 661 ISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSILSRSNGNLQLAIIWYFSPVST 720
Query: 721 NASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAV 780
NASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAV
Sbjct: 721 NASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAV 780
Query: 781 EEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVG 840
EEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVG
Sbjct: 781 EEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVG 840
Query: 841 SSATLYSVMWYWNRENSGSKLLVHLQHDGLLEYGEEGLRRHLHCYRSSSTDFVLKLHQVE 900
SSATLYSVMWYWNRENSGSKLLVHLQHDGLLEYGEEGLRRHLHCYRSSSTDFVLKLHQVE
Sbjct: 841 SSATLYSVMWYWNRENSGSKLLVHLQHDGLLEYGEEGLRRHLHCYRSSSTDFVLKLHQVE 900
Query: 901 MEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPTLPSRICSSAPLLYFLF 960
MEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPTLPSRICSSAPLLYFLF
Sbjct: 901 MEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPTLPSRICSSAPLLYFLF 960
Query: 961 ICPFVLLLLLLISLLCLYWKARKLSTLRSNTRKEKALWVDLKEAGGVTTNRREDEEEDEG 1020
ICPFVLLLLLLISLLCLYWKARKLSTLRSNTRKEKALWVDLKEAGGVTTNRREDEEEDEG
Sbjct: 961 ICPFVLLLLLLISLLCLYWKARKLSTLRSNTRKEKALWVDLKEAGGVTTNRREDEEEDEG 1020
Query: 1021 N 1021
N
Sbjct: 1021 N 1021
>gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo
sapiens]
Length = 1194
Score = 629 bits (1621), Expect = e-180
Identities = 366/961 (38%), Positives = 549/961 (57%), Gaps = 36/961 (3%)
Query: 10 FFLLLTKLSI-----GQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPT 64
FF +L+ L++ QR+VTVQ+GPL+R EG ++I CNV+G+QGPSEQ+FQWS+YLP+
Sbjct: 4 FFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPS 63
Query: 65 NPTQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTP 124
+P +EVQI+ST D++F YA+YTQRVR G +++ERVQGNS LLHI+ LQ +DAGEYECHTP
Sbjct: 64 SPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTP 123
Query: 125 NTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTW 184
+TD++Y+GSYSAK NL+VIPD+L T QTL + E +PL LTCE + T QH+HLSV W
Sbjct: 124 STDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAW 183
Query: 185 YLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQ 244
+ G + E+ISLS+DF+L Y +R + +V+L+KLG TTFRL+I LQ SDQ
Sbjct: 184 --LRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQ 241
Query: 245 GQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNI-TADSLFAEGKPLELV 303
G+ +CEA EWIQDPD +W +T+K+++ + +QP K+F V + T L G+P+E
Sbjct: 242 GEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFR 301
Query: 304 CLVVSSG-RDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSL 362
C++ + D W FN + IA + V L +++ R ++G+L+V+K F L
Sbjct: 302 CILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVL 361
Query: 363 KIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQ 422
KI+ L ED G Y C V E KT TG + + + + P + + P S+ + +
Sbjct: 362 KIYHLRQEDSGKYNCRVTEREKTVTGEF-IDKESKRPKNIPIIVLPLKSSISVEVASNAS 420
Query: 423 VVWEGETLAFLCK---AGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPS 479
V+ EGE L F C AG + SV W + R Q + + + +DG VQ G+SY S
Sbjct: 421 VILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDR-QNRRSNIMWLDRDGTVQPGSSYWERS 479
Query: 480 YHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSW------TQKISVT 533
G ++E++ +F L I + D G YEC V+E R A D W ++
Sbjct: 480 SFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR--AVDGEWQIVGERRASTPIS 537
Query: 534 VKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLI 593
+ +LE V+ +SR P V +++FDL C+++ Y VP++VTW+FQP + FH L+
Sbjct: 538 ITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHY-PAWVPVSVTWRFQPVGTVEFHDLV 596
Query: 594 RITHNGTIEWGNFLSRFQKKTKV--SQSLFRSQLLVHDATEEETGVYQCEVEVYDRNSLY 651
T +G ++WG+ S F+ +T + ++S +L + A++ E G YQC E++ +N Y
Sbjct: 597 TFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKN--Y 654
Query: 652 NNRPPR-ASAISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSILSRSNGNLQLA 710
NN R A S+ L I V P +KL+V+ + L N + CS+ S+++ N A
Sbjct: 655 NNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFA 714
Query: 711 IIWYFSPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEK-VSQDLFQLHILNVE 769
++WY S +A IL+ + + G + + E+ VS LF L + E
Sbjct: 715 VLWYVHKPS-DADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAE 773
Query: 770 DSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHRE 829
SD G Y+C VEEWLLS N W+KL E+ SG TE+ +K S++R+S+ +V E R+
Sbjct: 774 VSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQ 833
Query: 830 VAIRCSLESVGSSATLYSVMWY-WNRENSGSKLLVHLQHDGLLEYGEE----GLRRHLHC 884
V + C + + S + V W+ W + + + L D YGE+ L+ LH
Sbjct: 834 VQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHL 893
Query: 885 YRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPT 944
S + L + V ++D+G Y C V EW L W +A D + + LTV+ + +
Sbjct: 894 ESPSPGVYRLFIQNVAVQDSGTYSCHVEEW-LPSPSGMWYKRAEDTAGQTALTVMRPDAS 952
Query: 945 L 945
L
Sbjct: 953 L 953
Score = 267 bits (682), Expect = 4e-71
Identities = 276/1070 (25%), Positives = 448/1070 (41%), Gaps = 107/1070 (10%)
Query: 5 SYVASFFLLLTKLSIGQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPT 64
SY A L++ S+ + T L R E P+ + C V + QH SV
Sbjct: 132 SYSAKMNLVVIPDSL---QTTAMPQTLHRVEQDPLELTCEVASE---TIQHSHLSVAWLR 185
Query: 65 NPTQE--VQIIS-TKDAAF-SYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYE 120
E V++IS ++D S + Y QR G+V ++++ + L I LQ D GE+
Sbjct: 186 QKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFY 245
Query: 121 CHTPNTDEKYYGSYSAKTN-------LIVIPDTLSATMSSQTLGKEE--GEPLALTCEAS 171
C + GS+ A T + V P T+ +T + GEP+ C
Sbjct: 246 CEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILE 305
Query: 172 KATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTT 231
+ +V+W ++ I ++ + + V + R A +++ K +
Sbjct: 306 AQNVPDRYFAVSWAFN-------SSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSV 358
Query: 232 FRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITK--KQTDQTTLRIQPAVKDFQVNIT 289
F L I L+ D G+ C TE ++ T FI K K+ + + P V +
Sbjct: 359 FVLKIYHLRQEDSGKYNCRVTE--REKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVA 416
Query: 290 AD-SLFAEGKPLELVCLVVSSGRDP-QLQGIWFF-----NGTEIAHIDAGGVLGLKNDYK 342
++ S+ EG+ L C V ++GR + IW + I +D G + + Y
Sbjct: 417 SNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYW 476
Query: 343 ERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVL--QRKQSPD 400
ER+S G +Q+ ++ P +FSL IF+ EDEG Y C V E ++ G WQ++ +R +P
Sbjct: 477 ERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPI 536
Query: 401 SHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGG---AESPLSVSWWHIPRDQTQP 457
S L A + + T V ++ C A P+SV+W P +
Sbjct: 537 SITALEMGFAVTAISRTPG----VTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEF 592
Query: 458 EFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWAT-FQLEITFTAITDSGTYECRVSEK 516
+ +DG VQ G S+ T +EK + + +L I+ + T++G Y+C V+E
Sbjct: 593 HDLVTFTRDGGVQWGDRSS--SFRTRTAIEKAESSNNVRLSISRASDTEAGKYQC-VAEL 649
Query: 517 SRNQARDLSWTQKISVTVKSLE-------SSLQVSLMSRQPQVMLTNTFDLSCVVRAGYS 569
R + +WT+ T LE + LQVS R ++ L+C V++ S
Sbjct: 650 WRKNYNN-TWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTS 708
Query: 570 DLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNFL------SRFQKKTKVSQSLFRS 623
V W S +++ THN E+G + +R Q + VS LF
Sbjct: 709 Q-NSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLF-- 765
Query: 624 QLLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQ 683
L V A ++G Y C VE + + Y A +S + V P+S+L+++
Sbjct: 766 SLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYK-LAEEVSGRTEVTVKQPDSRLRLSQAQG 824
Query: 684 VQELSINSNTDIECSILSRSNGNLQLAIIWY-FSPVSTNASWLKILEMDQTNVIKTGDEF 742
+ +EC +L+R++ QL + W+ + P + L D T G++
Sbjct: 825 NLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDAT--FHYGEQA 882
Query: 743 HTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLT 802
K + H E S +++L I NV D G Y C VEEWL S +G W+K E +G T
Sbjct: 883 AKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQT 942
Query: 803 ELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVGSSATLYSVMWYWNRENSGSK-- 860
L + + ++V V V+E + CS+ S S + ++V WY R +G K
Sbjct: 943 ALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRS 1002
Query: 861 -----------------------------LLVHLQHDGLLEYGEEG--LRRHLHCYRSSS 889
L+ + D + +G EG L R S
Sbjct: 1003 SPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAV--FGPEGSPWEGRLRFQRLSP 1060
Query: 890 TDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPTLPSRI 949
+ L + Q +D G Y C V EW L +W +ES + + VL + PTL S I
Sbjct: 1061 VLYRLTVLQASPQDTGNYSCHVEEW-LPSPQKEWYRLTEEESAPIGIRVLDTSPTLQSII 1119
Query: 950 CSSAPLLYFLFICPFVLLLLLLISLLCLYWKARKLSTLRSNTRKEKALWV 999
CS+ L YF+F PF + +L+I++L + +K+R S LW+
Sbjct: 1120 CSNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSDGKNGVPLLWI 1169
>gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo
sapiens]
Length = 1214
Score = 620 bits (1598), Expect = e-177
Identities = 368/980 (37%), Positives = 549/980 (56%), Gaps = 54/980 (5%)
Query: 10 FFLLLTKLSI-----GQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPT 64
FF +L+ L++ QR+VTVQ+GPL+R EG ++I CNV+G+QGPSEQ+FQWS+YLP+
Sbjct: 4 FFPVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPS 63
Query: 65 NPTQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTP 124
+P +EVQI+ST D++F YA+YTQRVR G +++ERVQGNS LLHI+ LQ +DAGEYECHTP
Sbjct: 64 SPEREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTP 123
Query: 125 NTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTW 184
+TD++Y+GSYSAK NL+VIPD+L T QTL + E +PL LTCE + T QH+HLSV W
Sbjct: 124 STDKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVAW 183
Query: 185 YLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQ 244
+ G + E+ISLS+DF+L Y +R + +V+L+KLG TTFRL+I LQ SDQ
Sbjct: 184 --LRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQ 241
Query: 245 GQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNI-TADSLFAEGKPLELV 303
G+ +CEA EWIQDPD +W +T+K+++ + +QP K+F V + T L G+P+E
Sbjct: 242 GEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFR 301
Query: 304 CLVVSSG-RDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSL 362
C++ + D W FN + IA + V L +++ R ++G+L+V+K F L
Sbjct: 302 CILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVL 361
Query: 363 KIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQS------------------PDSHVH 404
KI+ L ED G Y C V E KT TG + + K+ P H
Sbjct: 362 KIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQL 421
Query: 405 LRK-PAARSVVMSTKNKQQVVWEGETLAFLCK---AGGAESPLSVSWWHIPRDQTQPEFV 460
L + S+ + + V+ EGE L F C AG + SV W + R Q + +
Sbjct: 422 LSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDR-QNRRSNI 480
Query: 461 AGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQ 520
+ +DG VQ G+SY S G ++E++ +F L I + D G YEC V+E R
Sbjct: 481 MWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR-- 538
Query: 521 ARDLSW------TQKISVTVKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVP 574
A D W +++ +LE V+ +SR P V +++FDL C+++ Y VP
Sbjct: 539 AVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHY-PAWVP 597
Query: 575 LTVTWQFQPASSHIFHQLIRITHNGTIEWGNFLSRFQKKTKV--SQSLFRSQLLVHDATE 632
++VTW+FQP + FH L+ T +G ++WG+ S F+ +T + ++S +L + A++
Sbjct: 598 VSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASD 657
Query: 633 EETGVYQCEVEVYDRNSLYNNRPPR-ASAISHPLRIAVTLPESKLKVNSRSQVQELSINS 691
E G YQC E++ +N YNN R A S+ L I V P +KL+V+ + L N
Sbjct: 658 TEAGKYQCVAELWRKN--YNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENK 715
Query: 692 NTDIECSILSRSNGNLQLAIIWYFSPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKF 751
+ CS+ S+++ N A++WY S +A IL+ + + G + +
Sbjct: 716 PIQLNCSVKSQTSQNSHFAVLWYVHKPS-DADGKLILKTTHNSAFEYGTYAEEEGLRARL 774
Query: 752 HTEK-VSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTG 810
E+ VS LF L + E SD G Y+C VEEWLLS N W+KL E+ SG TE+ +K
Sbjct: 775 QFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPD 834
Query: 811 SKVRVSKVYWTENVTEHREVAIRCSLESVGSSATLYSVMWY-WNRENSGSKLLVHLQHDG 869
S++R+S+ +V E R+V + C + + S + V W+ W + + + L D
Sbjct: 835 SRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDA 894
Query: 870 LLEYGEE----GLRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWIN 925
YGE+ L+ LH S + L + V ++D+G Y C V EW L W
Sbjct: 895 TFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEW-LPSPSGMWYK 953
Query: 926 QASDESQRMVLTVLPSEPTL 945
+A D + + LTV+ + +L
Sbjct: 954 RAEDTAGQTALTVMRPDASL 973
Score = 258 bits (658), Expect = 3e-68
Identities = 276/1090 (25%), Positives = 448/1090 (41%), Gaps = 127/1090 (11%)
Query: 5 SYVASFFLLLTKLSIGQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPT 64
SY A L++ S+ + T L R E P+ + C V + QH SV
Sbjct: 132 SYSAKMNLVVIPDSL---QTTAMPQTLHRVEQDPLELTCEVASE---TIQHSHLSVAWLR 185
Query: 65 NPTQE--VQIIS-TKDAAF-SYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYE 120
E V++IS ++D S + Y QR G+V ++++ + L I LQ D GE+
Sbjct: 186 QKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFY 245
Query: 121 CHTPNTDEKYYGSYSAKTN-------LIVIPDTLSATMSSQTLGKEE--GEPLALTCEAS 171
C + GS+ A T + V P T+ +T + GEP+ C
Sbjct: 246 CEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILE 305
Query: 172 KATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTT 231
+ +V+W ++ I ++ + + V + R A +++ K +
Sbjct: 306 AQNVPDRYFAVSWAFN-------SSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSV 358
Query: 232 FRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITK--KQTDQTTLRIQPAVKDFQVNIT 289
F L I L+ D G+ C TE ++ T FI K K+ + + P ++ V +
Sbjct: 359 FVLKIYHLRQEDSGKYNCRVTE--REKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVP 416
Query: 290 AD---------------------SLFAEGKPLELVCLVVSSGRDP-QLQGIWFF-----N 322
S+ EG+ L C V ++GR + IW
Sbjct: 417 QHHQLLSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNR 476
Query: 323 GTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEV 382
+ I +D G + + Y ER+S G +Q+ ++ P +FSL IF+ EDEG Y C V E
Sbjct: 477 RSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEW 536
Query: 383 MKTRTGSWQVL--QRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGG-- 438
++ G WQ++ +R +P S L A + + T V ++ C
Sbjct: 537 VRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTPG----VTYSDSFDLQCIIKPHY 592
Query: 439 -AESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWAT-FQL 496
A P+SV+W P + + +DG VQ G S+ T +EK + + +L
Sbjct: 593 PAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSS--SFRTRTAIEKAESSNNVRL 650
Query: 497 EITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLE-------SSLQVSLMSRQ 549
I+ + T++G Y+C V+E R + +WT+ T LE + LQVS R
Sbjct: 651 SISRASDTEAGKYQC-VAELWRKNYNN-TWTRLAERTSNLLEIRVLQPVTKLQVSKSKRT 708
Query: 550 PQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNFL-- 607
++ L+C V++ S V W S +++ THN E+G +
Sbjct: 709 LTLVENKPIQLNCSVKSQTSQ-NSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEE 767
Query: 608 ----SRFQKKTKVSQSLFRSQLLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASAISH 663
+R Q + VS LF L V A ++G Y C VE + + Y A +S
Sbjct: 768 EGLRARLQFERHVSGGLF--SLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYK-LAEEVSG 824
Query: 664 PLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSILSRSNGNLQLAIIWY-FSPVSTNA 722
+ V P+S+L+++ + +EC +L+R++ QL + W+ + P
Sbjct: 825 RTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPER 884
Query: 723 SWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEE 782
+ L D T G++ K + H E S +++L I NV D G Y C VEE
Sbjct: 885 ETVARLSRDAT--FHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEE 942
Query: 783 WLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVGSS 842
WL S +G W+K E +G T L + + ++V V V+E + CS+ S S
Sbjct: 943 WLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQ 1002
Query: 843 ATLYSVMWYWNRENSGSK-------------------------------LLVHLQHDGLL 871
+ ++V WY R +G K L+ + D +
Sbjct: 1003 DSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAV- 1061
Query: 872 EYGEEG--LRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASD 929
+G EG L R S + L + Q +D G Y C V EW L +W +
Sbjct: 1062 -FGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEW-LPSPQKEWYRLTEE 1119
Query: 930 ESQRMVLTVLPSEPTLPSRICSSAPLLYFLFICPFVLLLLLLISLLCLYWKARKLSTLRS 989
ES + + VL + PTL S ICS+ L YF+F PF + +L+I++L + +K+R S
Sbjct: 1120 ESAPIGIRVLDTSPTLQSIICSNDALFYFVFFYPFPIFGILIITILLVRFKSRNSSKNSD 1179
Query: 990 NTRKEKALWV 999
LW+
Sbjct: 1180 GKNGVPLLWI 1189
>gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens]
Length = 613
Score = 279 bits (714), Expect = 8e-75
Identities = 192/560 (34%), Positives = 278/560 (49%), Gaps = 59/560 (10%)
Query: 12 LLLTKLSIG--QREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQE 69
LLL L +G REV V +GPL+R G VSI CNVTG++GP++Q+F+W +Y P P
Sbjct: 16 LLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEAPDTA 75
Query: 70 VQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEK 129
+ I+STKD FSYAV+ RV +G+V V+R+QG++V+L I++LQ +DAG YECHTP+TD +
Sbjct: 76 LGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTR 135
Query: 130 YYGSYSAKTNLIVIPDTL------------SATMSSQTLGKEEGEPLALTCEASKATAQH 177
Y GSYS K L V+PD L A S + EG+ LAL C A +T +H
Sbjct: 136 YLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKH 195
Query: 178 THLSVTWYLT---QDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRL 234
THL+V++ + G S E++ + D + G Y ER AA +++L K G +R+
Sbjct: 196 THLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRM 255
Query: 235 SIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNI-TADSL 293
+ Q+ D G C A EWIQDPD +W I +K+ + +Q V + +
Sbjct: 256 VVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERR 315
Query: 294 FAEGKPLELVCLVVS----SGRDPQLQGIWFF-------NGTEIAHIDAGGVLGLKNDYK 342
G+PLEL+C V +GR W G +A +D GV L Y+
Sbjct: 316 IGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYE 375
Query: 343 ERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSH 402
R + + K+ + + L++ + P D G YRC+ ++ GS L+ S S
Sbjct: 376 GR----HIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVR---GSGTRLREAASARSR 428
Query: 403 ---VHLRKPAARSVVMSTKN--KQQVVWEGETLAFLCKAGGAESP----LSVSWW-HIPR 452
VH+R+ VV+ V+ GET + LC P L+ SWW P
Sbjct: 429 PLPVHVRE---EGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPE 485
Query: 453 D----QTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGT 508
D + V G+GQDG+ +LG G G +E + + +L + D G
Sbjct: 486 DGELSSVPAQLVGGVGQDGVAELGVRPG----GGPVSVELVGPRSHRLRLHSLGPEDEGV 541
Query: 509 YECRVSEKSRNQARDLSWTQ 528
Y C S + Q D SW Q
Sbjct: 542 YHCAPS--AWVQHADYSWYQ 559
Score = 89.4 bits (220), Expect = 2e-17
Identities = 130/535 (24%), Positives = 207/535 (38%), Gaps = 41/535 (7%)
Query: 297 GKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKND------YKERASQGEL 350
G + + C V Q WF E A A G++ K+ +K R GE+
Sbjct: 42 GTAVSISCNVTGYEGPAQQNFEWFLYRPE-APDTALGIVSTKDTQFSYAVFKSRVVAGEV 100
Query: 351 QVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQ-VLQRKQSPDS-HVHLRKP 408
QV +L A LKI L +D G Y C GS+ ++ + PD V P
Sbjct: 101 QVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPP 160
Query: 409 AARSVVMSTKNKQQVVWEGETLAFLCKAGGA---ESPLSVSWWH----IPRDQTQPEFVA 461
R T + V EG+ LA C A + + L+VS+ P ++ + V
Sbjct: 161 GPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVV 220
Query: 462 GMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQA 521
G+ D V+ GA Y G RL K +++ + D+GTY C +E ++
Sbjct: 221 GIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDP- 279
Query: 522 RDLSWTQKIS-------VTVKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGY--SDLK 572
D SW Q V V++L S L V++ + ++ +L C V +
Sbjct: 280 -DGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRH 338
Query: 573 VPLTVTWQFQPASSHIFHQLI-RITHNGTIEWG-NFLSRFQKKTKVSQSLFRSQLLVHDA 630
+V W+ PA + +L+ ++ G G + R KV+ +R +L A
Sbjct: 339 AAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRL--EAA 396
Query: 631 TEEETGVYQCEVEVYDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQVQELSIN 690
+ G Y+C + Y R S R ASA S PL + V L+ + +
Sbjct: 397 RPGDAGTYRCLAKAYVRGSGTRLREA-ASARSRPLPVHVREEGVVLEAVAWLAGGTVYRG 455
Query: 691 SNTDIECSILSRSNG-NLQLAIIWYFS-PVSTNASWLK---ILEMDQTNVIKTGDEFHTP 745
+ C+I R L+LA W+ P S + + + Q V + G
Sbjct: 456 ETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELG----VR 511
Query: 746 QRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSG 800
E V +L + ++ D G YHCA W+ + +W++ G +SG
Sbjct: 512 PGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAGSARSG 566
Score = 57.8 bits (138), Expect = 5e-08
Identities = 42/189 (22%), Positives = 83/189 (43%), Gaps = 6/189 (3%)
Query: 755 KVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVR 814
K D +++ + + D G YHC EW+ +G+W ++ EK++ L + ++ S++
Sbjct: 247 KEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLA 306
Query: 815 VSKVYWTENVTEHREVAIRCSLESVGSSA---TLYSVMWYWNRENS--GSKLLVHLQHDG 869
V+ + + + C++ A YSV W + +L+ L +G
Sbjct: 307 VTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEG 366
Query: 870 LLEYGEEGLRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASD 929
+ G RH+ + +S + L+L DAG Y C +A+ + G ++ AS
Sbjct: 367 VGSLGPGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRC-LAKAYVRGSGTRLREAASA 425
Query: 930 ESQRMVLTV 938
S+ + + V
Sbjct: 426 RSRPLPVHV 434
Score = 54.3 bits (129), Expect = 6e-07
Identities = 97/539 (17%), Positives = 191/539 (35%), Gaps = 49/539 (9%)
Query: 427 GETLAFLCKAGGAESPLSVSW-WHIPRDQTQPEFVAGMGQDGIVQLG-ASYGVPSYHGNT 484
G ++ C G E P ++ W + R + P+ G+ Q A + G
Sbjct: 42 GTAVSISCNVTGYEGPAQQNFEWFLYRPEA-PDTALGIVSTKDTQFSYAVFKSRVVAGEV 100
Query: 485 RLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLESSLQVS 544
+++++ L+I D+G YEC S++ K+ + V L LQVS
Sbjct: 101 QVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLG--SYSGKVELRV--LPDVLQVS 156
Query: 545 LMSRQPQVMLTNT------------FDLSCVVRAG---YSDLKVPLTVTWQFQPASSHIF 589
P+ T L C+ R ++ L V + P
Sbjct: 157 AAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTL 216
Query: 590 HQLIRITHNGTIEWGNFLSRFQKKTKV---SQSLFRSQLLVHDATEEETGVYQCEVE--V 644
+++ I + +E G + ++ + R +++V A + G Y C +
Sbjct: 217 QEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWI 276
Query: 645 YDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSI---LS 701
D + + + + ++H + V S+L V + + ++ C++ L
Sbjct: 277 QDPDGSWAQIAEKRAVLAH---VDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALP 333
Query: 702 RSNGNLQLAIIWYFSPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQDLF 761
+ + ++ W +P + ++D V G + + EKV+ +
Sbjct: 334 PAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEG----RHIAMEKVASRTY 389
Query: 762 QLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWT 821
+L + D G Y C + ++ + + +S + ++ G V + V W
Sbjct: 390 RLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEG--VVLEAVAWL 447
Query: 822 ENVTEHR--EVAIRCSLESVGSSATL-YSVMWYWNRENSG------SKLLVHLQHDGLLE 872
T +R ++ C++ G L + W+ R G ++L+ + DG+ E
Sbjct: 448 AGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAE 507
Query: 873 YGEEGLRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASDES 931
G + L+LH + ED G+Y C + W H S W S S
Sbjct: 508 LGVRPGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYS-WYQAGSARS 565
>gi|41152506 prostaglandin F2 receptor negative regulator [Homo
sapiens]
Length = 879
Score = 227 bits (579), Expect = 4e-59
Identities = 210/831 (25%), Positives = 365/831 (43%), Gaps = 64/831 (7%)
Query: 7 VASFFLLLTKLSIGQ---REVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLP 63
+AS LLL LS+ R V V L R G + I CNV+ + GPSEQ+F WS
Sbjct: 4 LASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWS--FS 61
Query: 64 TNPTQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHT 123
+ + V++ ST + F +Y +R++ G++ + R ++V LHI +Q D G Y+C T
Sbjct: 62 SLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCST 121
Query: 124 PNTDEKYYGSYSAKTNLIVIPDTLSATMSSQ---TLGKEEGEPLALTCEASKATAQHTHL 180
P+TD G+Y + V+ D+L S++ +L EGEP L C A+ A+ HTHL
Sbjct: 122 PSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHL 181
Query: 181 SVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQ 240
++ W + + G +++L+ + PG Y +R+ + DV+L+ +G +RLS+ R
Sbjct: 182 ALLWEVHR---GPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRAL 238
Query: 241 SSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPL 300
S+DQG C +EWI + W I +K + T+ IQP+V + + + AEGK L
Sbjct: 239 SADQGSYRCIVSEWIAE-QGNWQEIQEKAVEVATVVIQPSV--LRAAVPKNVSVAEGKEL 295
Query: 301 ELVC-LVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKA 359
+L C + D + + W F+ + + VL + S + +S + ++
Sbjct: 296 DLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARS 355
Query: 360 FSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKN 419
+ L + + E+ G Y C V+ SW + S + V + V +
Sbjct: 356 YHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNAS 415
Query: 420 KQQVVWEGETLAFLC-----KAGGAESPLSVSWWHIPRDQTQ----PEFVAGMGQDGIVQ 470
K + T C K+G A +VSW++ ++ E +A M D ++
Sbjct: 416 KVPGFADDPT-ELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLK 474
Query: 471 LGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKI 530
G + G+ K TF I T D G Y C VS ++ R+ SW +
Sbjct: 475 YGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQ--RNNSWVKSK 532
Query: 531 SVTVK------SLESSLQVSLMSRQPQVMLT--NTFDLSCVVRAGYSDLKVP--LTVTWQ 580
V K +LE S+ V + +RQP+ NTF+++C V + ++K P +
Sbjct: 533 DVFSKPVNIFWALEDSVLV-VKARQPKPFFAAGNTFEMTCKVSS--KNIKSPRYSVLIMA 589
Query: 581 FQP----ASSHIFHQLIRITHNGTIEWGNFLSRFQKK----TKVSQSLFRSQLLVHDATE 632
+P +S + +I + + ++ N+ + KV + FR ++ +
Sbjct: 590 EKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRM--YQTQV 647
Query: 633 EETGVYQCEVEVYD--RNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQVQELSIN 690
+ G+Y+C V + R SL+ A+++S+P+ I + S +
Sbjct: 648 SDAGLYRCMVTAWSPVRGSLWRE---AATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRG 704
Query: 691 SNTDIECSI----LSRSNGNLQLAIIWY-FSPVSTNASWLKILEMDQTNVIKTGDEFHTP 745
+ C I + ++ + W+ + + + + +D+ ++ T
Sbjct: 705 DLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRR---- 760
Query: 746 QRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGE 796
K E+VS F L + ED D G Y+C+V W+ S G+W K E
Sbjct: 761 DWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAE 811
Score = 147 bits (370), Expect = 7e-35
Identities = 188/835 (22%), Positives = 330/835 (39%), Gaps = 112/835 (13%)
Query: 209 PGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKK 268
P LY ER ++ L + L I+ +Q SDQG C
Sbjct: 79 PAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCS------------------ 120
Query: 269 QTDQTTLRIQPAVKD-FQVNITADSLFA-------------EGKPLELVCLVVS-SGRDP 313
T T +Q +D QV + ADSL EG+P EL C S S
Sbjct: 121 -TPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHT 179
Query: 314 QLQGIWFFNGTEIAHIDAGGVLGLKND--------YKERASQGELQVSKLGPKAFSLKIF 365
L +W + VL L ++ Y++R G++++ +G A+ L +
Sbjct: 180 HLALLWEVHRGPARR----SVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVS 235
Query: 366 SLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVW 425
D+G+YRC+V+E + + G+WQ +Q K + V ++ R+ V K V
Sbjct: 236 RALSADQGSYRCIVSEWIAEQ-GNWQEIQEKAVEVATVVIQPSVLRAAVP----KNVSVA 290
Query: 426 EGETLAFLC-----KAGGAESPLSVSWWHIPRDQTQP--EFVAGMGQDGIVQLGASYGVP 478
EG+ L C +A ++ S+ +P D T P +A + +D +V
Sbjct: 291 EGKELDLTCNITTDRADDVRPEVTWSFSRMP-DSTLPGSRVLARLDRDSLVHSSP----- 344
Query: 479 SYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKS-- 536
+ L +D ++ L + + +SG Y C VS + R SW K++ V S
Sbjct: 345 ----HVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNR--SW-HKVAEAVSSPA 397
Query: 537 ------LESSLQVSLMSRQPQVMLTNTFDLSC-VVRAGYSDLKVPLTVTWQFQP---ASS 586
LE QV L + + + +L+C VV + V TV+W ++ + +
Sbjct: 398 GVGVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDN 457
Query: 587 HIFHQLIRITHNG-TIEWGNFLSRFQKKTKVSQSLFRSQ------LLVHDATEEETGVYQ 639
+ +L+ + T+++G R +++ + +F + + TEE+ G Y
Sbjct: 458 VVTSELLAVMDGDWTLKYGE---RSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYY 514
Query: 640 CEVEVYDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSI 699
C V + + N+ S P+ I L +S L V +R + + ++ C +
Sbjct: 515 CVVSAWTKQR-NNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKV 573
Query: 700 LSRSNGNLQLAI-IWYFSPVSTNASWLK---ILEMDQTNVIKTGDEFHTPQRKQKFHTEK 755
S++ + + ++ I PV +S + I+ +DQ +V+K + + R EK
Sbjct: 574 SSKNIKSPRYSVLIMAEKPVGDLSSPNETKYIISLDQDSVVKL-ENWTDASRVDGVVLEK 632
Query: 756 VSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRV 815
V +D F+ + + SD G Y C V W W + S E+ + +G
Sbjct: 633 VQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNA 692
Query: 816 SKVYWTENVTEHREVAIRCSLESVGSSA----TLYSVMWYWNRE---NSGSKLLVHLQHD 868
S T +V + + C + G++ + V W+ + LL L
Sbjct: 693 SVHSDTPSVIRGDLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRK 752
Query: 869 GLLEYGEEGLRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQAS 928
G++ + L R S +F+L++H E +D G Y+C V W + W +A
Sbjct: 753 GIVTTSRRDWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPW-VKSPTGSWQKEAE 811
Query: 929 DESQRMVLTVLPSEPTLPSRICSSAPLLYFLFICPFVLLLLLLISLLCLYWKARK 983
S+ + +TV + PLL + + + LL LI +W +K
Sbjct: 812 IHSKPVFITV-----KMDVLNAFKYPLLIGVGLSTVIGLLSCLIGYCSSHWCCKK 861
>gi|239753216 PREDICTED: similar to immunoglobulin superfamily,
member 3 [Homo sapiens]
Length = 376
Score = 194 bits (494), Expect = 3e-49
Identities = 118/329 (35%), Positives = 179/329 (54%), Gaps = 7/329 (2%)
Query: 192 GSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEA 251
G + E+ISLS+DF+L G Y R + +V+L+KLG TTFRL+I LQ SDQG+ +CEA
Sbjct: 22 GEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEA 81
Query: 252 TEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNI-TADSLFAEGKPLELVCLVVSSG 310
EWIQ+PD +W +T+K+++ + +QP K+F V + T L G+P+E C+ +
Sbjct: 82 AEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQN 141
Query: 311 -RDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGP 369
D W FN + IA + V L +++ R ++G+L V+K F LKI+ L
Sbjct: 142 VPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQ 201
Query: 370 EDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGET 429
ED G Y C V E KT TG + + + + P + + P S+ + + V+ EGE
Sbjct: 202 EDSGKYNCRVTEREKTVTGEF-IDKESKHPKNIPIIVLPLESSISVEVASNASVILEGED 260
Query: 430 LAFLCK---AGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRL 486
L F C AG + SV W + R Q + + + +DG VQ G+SY S G+ ++
Sbjct: 261 LRFSCSVRMAGRPQGRFSVIWQLVDR-QNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQM 319
Query: 487 EKMDWATFQLEITFTAITDSGTYECRVSE 515
E++ +F L I + D G YEC V+E
Sbjct: 320 EQVQPNSFSLGIFNSRKEDEGQYECHVTE 348
Score = 97.1 bits (240), Expect = 8e-20
Identities = 91/357 (25%), Positives = 152/357 (42%), Gaps = 29/357 (8%)
Query: 69 EVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDE 128
EV +S S + Y R G+V ++++ + L I LQ D GE+ C +
Sbjct: 27 EVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQ 86
Query: 129 KYYGSYSAKTN-------LIVIPDTLSATMSSQTLGKEE--GEPLALTCEASKATAQHTH 179
GS+ A T + V P T+ +T + GEP+ C +
Sbjct: 87 NPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRY 146
Query: 180 LSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERL 239
+V+W ++ I ++ + + V + R A + + K + F L I L
Sbjct: 147 FAVSWAFN-------SSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHL 199
Query: 240 QSSDQGQLFCEATEWIQDPDETWMFITK--KQTDQTTLRIQPAVKDFQVNITAD-SLFAE 296
+ D G+ C TE ++ T FI K K + + P V + ++ S+ E
Sbjct: 200 RQEDSGKYNCRVTE--REKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILE 257
Query: 297 GKPLELVCLVVSSGRDP-QLQGIWFF-----NGTEIAHIDAGGVLGLKNDYKERASQGEL 350
G+ L C V +GR + IW ++I +D G + + Y ER+S G +
Sbjct: 258 GEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSV 317
Query: 351 QVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVL--QRKQSPDSHVHL 405
Q+ ++ P +FSL IF+ EDEG Y C V E ++ G WQ++ +R +P S + L
Sbjct: 318 QMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374
Score = 86.3 bits (212), Expect = 1e-16
Identities = 54/245 (22%), Positives = 118/245 (48%), Gaps = 10/245 (4%)
Query: 716 SPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGK 775
+P ++++ + + ++ +G E+ Q + +K+ + F+L I +++ SD+G+
Sbjct: 17 APCKVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGE 76
Query: 776 YHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCS 835
++C EW+ + +G+W+ + K+S + ++PT + V V RC
Sbjct: 77 FYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCI 136
Query: 836 LESVGSSATLYSVMWYWNRENSGSKLLVHLQHDGL----LEYGEEGLRRHLHCYRSSSTD 891
E+ ++V W +N S L+ + + + E+ R L+ + S +
Sbjct: 137 PEAQNVPDRYFAVSWAFN-----SSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSV 191
Query: 892 FVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPTLPSRICS 951
FVLK++ + ED+G Y CRV E + ++I++ S + + + VLP E ++ + S
Sbjct: 192 FVLKIYHLRQEDSGKYNCRVTERE-KTVTGEFIDKESKHPKNIPIIVLPLESSISVEVAS 250
Query: 952 SAPLL 956
+A ++
Sbjct: 251 NASVI 255
Score = 82.8 bits (203), Expect = 2e-15
Identities = 87/357 (24%), Positives = 143/357 (40%), Gaps = 28/357 (7%)
Query: 456 QPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSE 515
+P V + +D ++ G+ Y G RL+K+ TF+L I +D G + C +E
Sbjct: 24 KPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAE 83
Query: 516 KSRNQARDLSW---TQKIS----VTVKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGY 568
+N D SW T+K S V V+ E V L + + M+ + C+ A
Sbjct: 84 WIQNP--DGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQ- 140
Query: 569 SDLKVP---LTVTWQFQPASSHIFHQLIRITHNGTIEWGNFLSRFQKKT-KVSQSLFRSQ 624
VP V+W F SS I E+ + +R Q K S S+F
Sbjct: 141 ---NVPDRYFAVSWAFN--SSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVF--V 193
Query: 625 LLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASAISHPLRIAV-TLP-ESKLKVNSRS 682
L ++ +E++G Y C V ++ + HP I + LP ES + V S
Sbjct: 194 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESK---HPKNIPIIVLPLESSISVEVAS 250
Query: 683 QVQELSINSNTDIECSILSRSNGNLQLAIIWYFSPVSTNASWLKILEMDQTNVIKTGDEF 742
+ + CS+ + ++IW S I+ +D+ ++ G +
Sbjct: 251 NASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRS--DIMWLDRDGTVQPGSSY 308
Query: 743 HTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKS 799
E+V + F L I N D G+Y C V EW+ +G W +GE+++
Sbjct: 309 WERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRA 365
Score = 62.0 bits (149), Expect = 3e-09
Identities = 65/308 (21%), Positives = 120/308 (38%), Gaps = 22/308 (7%)
Query: 615 KVSQSLFRSQLLVHDATEEETGVYQCEVEVYDRN---SLYNNRPPRASAISHPLRIAVTL 671
K+ ++ FR L + + G + CE + +N S Y R+ + V
Sbjct: 56 KLGRTTFR--LTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAV----VNVQP 109
Query: 672 PESKLKVNSRSQVQELSINSNTDIECSILSRSNGNLQLAIIWYFSPVSTNASWLKILEMD 731
E + V ++ + + + C +++ + A+ W F N+S + + +
Sbjct: 110 TEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAF-----NSSLIATMGPN 164
Query: 732 QTNVIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTW 791
V+ + EF + + + + K S +F L I ++ D GKY+C V E + G +
Sbjct: 165 AVPVLNS--EFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEF 222
Query: 792 HKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVGSSATLYSVMWY 851
K + + P S + V + E ++ CS+ G +SV+W
Sbjct: 223 IDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQ 282
Query: 852 W-NRENSGSKLLVHLQHDGLLE----YGEEGLRRHLHCYRSSSTDFVLKLHQVEMEDAGM 906
+R+N S ++ L DG ++ Y E + + F L + ED G
Sbjct: 283 LVDRQNRRSDIM-WLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQ 341
Query: 907 YWCRVAEW 914
Y C V EW
Sbjct: 342 YECHVTEW 349
>gi|169215606 PREDICTED: similar to immunoglobulin superfamily,
member 3 [Homo sapiens]
Length = 195
Score = 173 bits (439), Expect = 6e-43
Identities = 74/113 (65%), Positives = 100/113 (88%)
Query: 21 QREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQEVQIISTKDAAF 80
QR+VTVQ+GPL+R EG ++I CNV+G+QGPSEQ+FQWS+YLP++P +EVQI+ST D++F
Sbjct: 83 QRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTMDSSF 142
Query: 81 SYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGS 133
YA+YTQRVR G +++ERVQGN LLHI+ LQ +DAGEYECHTP+T+++Y+GS
Sbjct: 143 PYAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECHTPSTEKQYFGS 195
>gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens]
Length = 155
Score = 173 bits (439), Expect = 6e-43
Identities = 74/113 (65%), Positives = 100/113 (88%)
Query: 21 QREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQEVQIISTKDAAF 80
QR+VTVQ+GPL+R EG ++I CNV+G+QGPSEQ+FQWS+YLP++P +EVQI+ST D++F
Sbjct: 43 QRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTMDSSF 102
Query: 81 SYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGS 133
YA+YTQRVR G +++ERVQGN LLHI+ LQ +DAGEYECHTP+T+++Y+GS
Sbjct: 103 PYAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECHTPSTEKQYFGS 155
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 55.8 bits (133), Expect = 2e-07
Identities = 114/524 (21%), Positives = 182/524 (34%), Gaps = 132/524 (25%)
Query: 81 SYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNL 140
++A T R G + R Q + LL + ++ D+GEY CH T S
Sbjct: 2179 AHAQVTWHKRGGSLPA-RHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEA 2237
Query: 141 IVIPDTL-SATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEII 199
VIP + + S + EG+ L L+C A H VTWY + GG A +
Sbjct: 2238 SVIPGPIPPVRIESSSSTVAEGQTLDLSC----VVAGQAHAQVTWY--KRGGSLPARHQV 2291
Query: 200 SLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPD 259
S+ +I P +D GQ C A+ +
Sbjct: 2292 RGSRLYIFQASP------------------------------ADAGQYVCRASNGM---- 2317
Query: 260 ETWMFITKKQTDQTTLRIQPAVKDFQVNI-TADSLFAEGKPLELVCLVVSSGRDPQLQGI 318
E + +T T L PA + I + S AEG+ L+L C+V
Sbjct: 2318 EASITVTVTGTQGANL-AYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSH------- 2369
Query: 319 WFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCV 378
++ GG L +++ + G L L+++ P D G Y C
Sbjct: 2370 -----AQVTWHKRGGSLPVRHQ-----THGSL-----------LRLYQASPADSGEYVC- 2407
Query: 379 VAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSV-------VMSTKNKQQVVWEGETLA 431
+VL ++ V + A SV + ++ V EG+TL
Sbjct: 2408 ------------RVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLD 2455
Query: 432 FLCKAGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDW 491
C G ++ V+W + G+ HG+
Sbjct: 2456 LNCLVAG-QAHAQVTWHK--------------------RGGSLPARHQVHGS-------- 2486
Query: 492 ATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWT--QKISVTVKSLESSLQVSLMSRQ 549
+L + DSG Y CRV S Q + T Q++S + S + V + S
Sbjct: 2487 ---RLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGS-HSQGVAYPVRIESSS 2542
Query: 550 PQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLI 593
+ +T DL+C+V + + P T+TW + S HQ++
Sbjct: 2543 ASLANGHTLDLNCLVAS-----QAPHTITWYKRGGSLPSRHQIV 2581
Score = 49.3 bits (116), Expect = 2e-05
Identities = 134/608 (22%), Positives = 208/608 (34%), Gaps = 159/608 (26%)
Query: 34 AEGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQEVQIISTKDAAF------------- 80
+ G SI VTG QG + + P TQ ++I +
Sbjct: 2314 SNGMEASITVTVTGTQGANLAY-------PAGSTQPIRIEPSSSQVAEGQTLDLNCVVPG 2366
Query: 81 -SYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSY----- 134
S+A T R G + V R Q + LL + + D+GEY C + S
Sbjct: 2367 QSHAQVTWHKRGGSLPV-RHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIE 2425
Query: 135 --SAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGG 192
+ L V P + SSQ EG+ L L C A H VTW+ + GG
Sbjct: 2426 PAGSVPALGVTPTVRIESSSSQV---AEGQTLDLNC----LVAGQAHAQVTWH--KRGGS 2476
Query: 193 SQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEAT 252
A + S RL + ++ +D G+ C
Sbjct: 2477 LPARHQVHGS------------------------------RLRLLQVTPADSGEYVCRVV 2506
Query: 253 EWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRD 312
E + +T +Q + Q ++ ++ SL A G L+L CLV S
Sbjct: 2507 -GSSGTQEASVLVTIQQR-LSGSHSQGVAYPVRIESSSASL-ANGHTLDLNCLVASQAPH 2563
Query: 313 PQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDE 372
W+ G + S+ ++ S+ L+I + P D
Sbjct: 2564 TI---TWYKRGGSL------------------PSRHQIVGSR-------LRIPQVTPADS 2595
Query: 373 GAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAF 432
G Y C V+ +R S ++ + S SHV P R ++ V EG+TL
Sbjct: 2596 GEYVCHVSNGAGSRETS-LIVTIQGSGSSHVPSVSPPIR-----IESSSPTVVEGQTLDL 2649
Query: 433 LCKAGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYH----GNTRLEK 488
C A P ++ W+ + G S +PS H + RL +
Sbjct: 2650 NCVV--ARQPQAIITWY--------------------KRGGS--LPSRHQTHGSHLRLHQ 2685
Query: 489 MDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLE---SSLQVSL 545
M ++ DSG Y CR + + A + S +S + S SS+ + +
Sbjct: 2686 M------------SVADSGEYVCRAN--NNIDALEASIVISVSPSAGSPSAPGSSMPIRI 2731
Query: 546 MSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQL----IRITHNGTI 601
S V T DL+CVV + VTW + S HQ +R+ H
Sbjct: 2732 ESSSSHVAEGETLDLNCVVPG-----QAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPA 2786
Query: 602 EWGNFLSR 609
+ G ++ R
Sbjct: 2787 DSGEYVCR 2794
Score = 31.6 bits (70), Expect = 4.0
Identities = 69/358 (19%), Positives = 122/358 (34%), Gaps = 81/358 (22%)
Query: 98 RVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSY-----SAKTNLIVIPDTLSAT-- 150
+ +G+ + LH + D+GEY C + S ++ ++ + +P A
Sbjct: 2772 QTRGSRLRLH--HVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPI 2829
Query: 151 -MSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVP 209
+ + EG+ L L C H VTW+ + GG A V
Sbjct: 2830 RIEPSSSRVAEGQTLDLKC----VVPGQAHAQVTWH--KRGGNLPARH---------QVH 2874
Query: 210 GPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQ 269
GPL ++LN++ P +D G+ C+ T E + +T +
Sbjct: 2875 GPL---------LRLNQVSP------------ADSGEYSCQVTG-SSGTLEASVLVTIEP 2912
Query: 270 TDQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHI 329
+ + + + ++ + EG+ L+L C+V Q W+ G
Sbjct: 2913 SSPGPIPAPGLAQPIYIEASSSHV-TEGQTLDLNCVVPGQAH---AQVTWYKRGGS---- 2964
Query: 330 DAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGS 389
L ++ SQ L++ + P D G Y C A +
Sbjct: 2965 -------LPARHQTHGSQ--------------LRLHLVSPADSGEYVCRAASGPGPEQEA 3003
Query: 390 WQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSW 447
+ S S LR P V+S V +G+ +F C +P+S+ W
Sbjct: 3004 SFTVTVPPSEGSSYRLRSP-----VISIDPPSSTVQQGQDASFKCLIHDGAAPISLEW 3056
Score = 31.2 bits (69), Expect = 5.2
Identities = 55/251 (21%), Positives = 90/251 (35%), Gaps = 49/251 (19%)
Query: 362 LKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQ 421
L++ ++ P D+ Y C + + + Q + R + +H+ V +S + Q
Sbjct: 1918 LRLPAVEPTDQAQYLC------RAHSSAGQQVAR-----AVLHVHGGGGPRVQVSPERTQ 1966
Query: 422 QVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYH 481
V G T+ C+A G P + W P+
Sbjct: 1967 --VHAGRTVRLYCRAAGV--PSATITWRKEGGSLPPQ----------------------- 1999
Query: 482 GNTRLEKMDWATFQLEITFTAITDSGTYEC-RVSEKSRNQARDLSWTQKISVTVKSLESS 540
R E+ D AT + TA D+G Y C S QAR ++ V S S
Sbjct: 2000 --ARSERTDIATLLIPAITTA--DAGFYLCVATSPAGTAQARI-----QVVVLSASDASP 2050
Query: 541 LQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGT 600
V + S P V T DL+CVV AG + +V P + + +R+
Sbjct: 2051 PPVKIESSSPSVTEGQTLDLNCVV-AGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSP 2109
Query: 601 IEWGNFLSRFQ 611
+ G ++ R +
Sbjct: 2110 ADSGEYVCRVE 2120
>gi|24111244 MAM domain containing glycosylphosphatidylinositol
anchor 1 [Homo sapiens]
Length = 955
Score = 52.8 bits (125), Expect = 2e-06
Identities = 73/338 (21%), Positives = 125/338 (36%), Gaps = 74/338 (21%)
Query: 234 LSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSL 293
L IER+ + G+ +C+A + P + + + D+ L + V D + N
Sbjct: 93 LRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPMLTVHQTVSDVRGN------ 146
Query: 294 FAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVS 353
F + K + L C V S +P + IW ++H GV + Y+ +QGE +V
Sbjct: 147 FYQEKTVFLRCTVNS---NPPARFIWKRGSDTLSHSQDNGV----DIYEPLYTQGETKV- 198
Query: 354 KLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHV--HLRKPAAR 411
LK+ +L P+D +Y C V+ V PD + L A
Sbjct: 199 --------LKLKNLRPQDYASYTCQVS-----------VRNVCGIPDKAITFRLTNTTAP 239
Query: 412 SVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQL 471
+ + N+ VV GE + C G + + W H P G G +
Sbjct: 240 PALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLQWSHGP----------GPLPLGALAQ 289
Query: 472 GASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKIS 531
G + +PS DSG Y C + N A+ + ++
Sbjct: 290 GGTLSIPSVQAR---------------------DSGYYNCTATNNVGNPAK-----KTVN 323
Query: 532 VTVKSLESS---LQVSLMSRQPQVMLTNTFDLSCVVRA 566
+ V+S++++ + ++ + L LSC V A
Sbjct: 324 LLVRSMKNATFQITPDVIKESENIQLGQDLKLSCHVDA 361
Score = 31.2 bits (69), Expect = 5.2
Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 21/147 (14%)
Query: 234 LSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSL 293
LSI +Q+ D G C AT + +P + + + + T +I P V NI
Sbjct: 293 LSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSMKNATFQITPDVIKESENIQL--- 349
Query: 294 FAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVS 353
G+ L+L C V + ++ ++ WF NG + +L +ND
Sbjct: 350 ---GQDLKLSCHVDAVPQE-KVTYQWFKNGKPARM--SKRLLVTRND------------P 391
Query: 354 KLGPKAFSLKIFSLGPEDEGAYRCVVA 380
+L SL++ L D G Y C+ +
Sbjct: 392 ELPAVTSSLELIDLHFSDYGTYLCMAS 418
>gi|222144244 fibroblast growth factor receptor 2 isoform 9
precursor [Homo sapiens]
Length = 680
Score = 47.4 bits (111), Expect = 7e-05
Identities = 63/248 (25%), Positives = 96/248 (38%), Gaps = 47/248 (18%)
Query: 736 IKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLG 795
+K G EF +++ + KV + L + +V SD+G Y C VE S N T+H
Sbjct: 103 LKNGKEF---KQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDV 159
Query: 796 EKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVGSSATLYSVMWYWNRE 855
++S + G S V + V C + S + W + E
Sbjct: 160 VERS--PHRPILQAGLPANASTVVGGD-------VEFVCKVYSDAQP----HIQWIKHVE 206
Query: 856 NSGSKLLVHLQHDGLLEYGEEGL---RRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVA 912
+GSK YG +GL + H +SS VL L V DAG Y C+V+
Sbjct: 207 KNGSK------------YGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICKVS 254
Query: 913 EWQLHGHPSKWINQASDESQRMVLTVLPSE--PTLPSRICSSAPLLYFLFIC--PFVLLL 968
+ + S W LTVLP + P I +S L C F++
Sbjct: 255 NYIGQANQSAW------------LTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIAC 302
Query: 969 LLLISLLC 976
+++ +LC
Sbjct: 303 MVVTVILC 310
>gi|222144231 fibroblast growth factor receptor 2 isoform 3
precursor [Homo sapiens]
Length = 769
Score = 47.4 bits (111), Expect = 7e-05
Identities = 63/248 (25%), Positives = 96/248 (38%), Gaps = 47/248 (18%)
Query: 736 IKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLG 795
+K G EF +++ + KV + L + +V SD+G Y C VE S N T+H
Sbjct: 192 LKNGKEF---KQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDV 248
Query: 796 EKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVGSSATLYSVMWYWNRE 855
++S + G S V + V C + S + W + E
Sbjct: 249 VERS--PHRPILQAGLPANASTVVGGD-------VEFVCKVYSDAQP----HIQWIKHVE 295
Query: 856 NSGSKLLVHLQHDGLLEYGEEGL---RRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVA 912
+GSK YG +GL + H +SS VL L V DAG Y C+V+
Sbjct: 296 KNGSK------------YGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICKVS 343
Query: 913 EWQLHGHPSKWINQASDESQRMVLTVLPSE--PTLPSRICSSAPLLYFLFIC--PFVLLL 968
+ + S W LTVLP + P I +S L C F++
Sbjct: 344 NYIGQANQSAW------------LTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIAC 391
Query: 969 LLLISLLC 976
+++ +LC
Sbjct: 392 MVVTVILC 399
>gi|221316638 fibroblast growth factor receptor 2 isoform 2
precursor [Homo sapiens]
Length = 822
Score = 47.4 bits (111), Expect = 7e-05
Identities = 63/248 (25%), Positives = 96/248 (38%), Gaps = 47/248 (18%)
Query: 736 IKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLG 795
+K G EF +++ + KV + L + +V SD+G Y C VE S N T+H
Sbjct: 192 LKNGKEF---KQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDV 248
Query: 796 EKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVGSSATLYSVMWYWNRE 855
++S + G S V + V C + S + W + E
Sbjct: 249 VERS--PHRPILQAGLPANASTVVGGD-------VEFVCKVYSDAQP----HIQWIKHVE 295
Query: 856 NSGSKLLVHLQHDGLLEYGEEGL---RRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVA 912
+GSK YG +GL + H +SS VL L V DAG Y C+V+
Sbjct: 296 KNGSK------------YGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICKVS 343
Query: 913 EWQLHGHPSKWINQASDESQRMVLTVLPSE--PTLPSRICSSAPLLYFLFIC--PFVLLL 968
+ + S W LTVLP + P I +S L C F++
Sbjct: 344 NYIGQANQSAW------------LTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIAC 391
Query: 969 LLLISLLC 976
+++ +LC
Sbjct: 392 MVVTVILC 399
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 47.0 bits (110), Expect = 9e-05
Identities = 51/216 (23%), Positives = 81/216 (37%), Gaps = 47/216 (21%)
Query: 233 RLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADS 292
RL+I D G C+AT+ K QT + T+ ++ K + +
Sbjct: 77 RLTIYNANIEDAGIYRCQATD------------AKGQTQEATVVLEIYQKLTFREVVSPQ 124
Query: 293 LFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQV 352
F +G+ E+VC V SS P W ++ E+ I L N+
Sbjct: 125 EFKQGEDAEVVCRVSSS---PAPAVSWLYHNEEVTTISDNRFAMLANN------------ 169
Query: 353 SKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARS 412
+L+I ++ DEG YRC G + D V + P A
Sbjct: 170 --------NLQILNINKSDEGIYRC---------EGRVEARGEIDFRDIIVIVNVPPA-- 210
Query: 413 VVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSWW 448
+ M K+ GE + F C+A G+ P ++SW+
Sbjct: 211 ISMPQKSFNATAERGEEMTFSCRASGSPEP-AISWF 245
>gi|190341099 hypothetical protein LOC196740 isoform 1 [Homo
sapiens]
Length = 320
Score = 46.6 bits (109), Expect = 1e-04
Identities = 49/190 (25%), Positives = 82/190 (43%), Gaps = 14/190 (7%)
Query: 426 EGETLAFLCKAGGA---ESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYHG 482
EGE LC +S L+V W+ +Q + M + +VQ ++ +
Sbjct: 38 EGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRR 97
Query: 483 NTRL-EKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVT---VKSLE 538
RL E+ A ++L + +D G Y CRV E SR++ + +W+ S T V SL+
Sbjct: 98 RLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQEISRHRNKWTAWSNGSSATEMRVISLK 157
Query: 539 SSLQVSL-MSRQPQVMLTNTF---DLSCVVRAGYSDLKVPLTVTWQ--FQPASSHIFHQL 592
+S + S +++ + + L C V S L L + WQ F S + H L
Sbjct: 158 ASEESSFEKTKETWAFFEDLYVYAVLVCCVGI-LSILLFMLVIVWQSVFNKRKSRVRHYL 216
Query: 593 IRITHNGTIE 602
++ N + E
Sbjct: 217 VKCPQNSSGE 226
Score = 38.1 bits (87), Expect = 0.043
Identities = 24/107 (22%), Positives = 53/107 (49%), Gaps = 9/107 (8%)
Query: 692 NTDIECSILSRSNGNLQLAIIWYFSPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKF 751
N + C + + + LA+ W+F+ S ++ +++M + V++ F ++++
Sbjct: 41 NATLLCHVSQKRRKDSLLAVRWFFAH-SFDSQEALMVKMTKLRVVQYYGNFSRSAKRRRL 99
Query: 752 HT-EKVSQDLFQLHILNVEDSDRGKYHCAVEE-------WLLSTNGT 790
E+ L++L +L ++ SD+G Y C V+E W +NG+
Sbjct: 100 RLLEEQRGALYRLSVLTLQPSDQGHYVCRVQEISRHRNKWTAWSNGS 146
Score = 33.5 bits (75), Expect = 1.0
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 10/99 (10%)
Query: 160 EGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAA 219
EGE L C S+ + + L+V W+ +A ++ ++K ++ Y F+
Sbjct: 38 EGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEAL-MVKMTKLRVVQ----YYGNFSR 92
Query: 220 SDVQ-----LNKLGPTTFRLSIERLQSSDQGQLFCEATE 253
S + L + +RLS+ LQ SDQG C E
Sbjct: 93 SAKRRRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131
Score = 30.4 bits (67), Expect = 8.9
Identities = 34/169 (20%), Positives = 71/169 (42%), Gaps = 16/169 (9%)
Query: 826 EHREVAIRCSLESVGSSATLYSVMWYWNRE-NSGSKLLVHLQHDGLLEY----GEEGLRR 880
E + C + +L +V W++ +S L+V + +++Y RR
Sbjct: 38 EGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRR 97
Query: 881 HLHCYRSS-STDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWI--NQASDESQRMVLT 937
L + L + ++ D G Y CRV E + H +KW + S ++ V++
Sbjct: 98 RLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE--ISRHRNKWTAWSNGSSATEMRVIS 155
Query: 938 VLPSEPTLPSRICSSAPL-----LYFLFICPFVLLLLLLISLLCLYWKA 981
+ SE + + + +Y + +C V +L +L+ +L + W++
Sbjct: 156 LKASEESSFEKTKETWAFFEDLYVYAVLVC-CVGILSILLFMLVIVWQS 203
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 45.8 bits (107), Expect = 2e-04
Identities = 88/387 (22%), Positives = 138/387 (35%), Gaps = 94/387 (24%)
Query: 69 EVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNT-- 126
E ++ T S+ + +RSG Y + +HI + D GEY+C N
Sbjct: 7419 ECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVG 7478
Query: 127 DEKYYGSYSAKTNLIVIPDTLSATMS--SQTLGKEEGEPLALTCEASKATAQHTHLSVTW 184
+ GS + K P +S S +GKE L T E ++ +SV W
Sbjct: 7479 SDTCVGSIALKA-----PPRFVKKLSDISTVVGKE--VQLQTTIEGAEP------ISVVW 7525
Query: 185 YLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQ 244
+ +D G EI+ S + + Y+E A L R++ ++
Sbjct: 7526 F--KDKG-----EIVRESDNIWI----SYSENIAT--------------LQFSRVEPANA 7560
Query: 245 GQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPLELVC 304
G+ C+ D F T + T+ +P + +T G L C
Sbjct: 7561 GKYTCQIK---NDAGMQECFATLSVLEPATIVEKPE----SIKVTT------GDTCTLEC 7607
Query: 305 LVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKI 364
V + P+L WF +G KE S + ++S K LKI
Sbjct: 7608 TVAGT---PELSTKWFKDG------------------KELTSDNKYKISFFN-KVSGLKI 7645
Query: 365 FSLGPEDEGAYRCVVAEVM--KTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQ 422
++ P D G Y V + + T S QV R P + K K+
Sbjct: 7646 INVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPS--------------FTRKLKET 7691
Query: 423 VVWEGETLAFLCKAGGAESPLSVSWWH 449
G ++ CK G+ P+SVSW+H
Sbjct: 7692 NGLSGSSVVMECKVYGS-PPISVSWFH 7717
Score = 42.7 bits (99), Expect = 0.002
Identities = 141/680 (20%), Positives = 236/680 (34%), Gaps = 197/680 (28%)
Query: 105 LLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPL 164
+L I +DAG+Y C N E A + + P ++ + L G+ +
Sbjct: 6042 ILEILNSTKRDAGQYSCEIEN--EAGRDVCGALVSTLEPPYFVT---ELEPLEAAVGDSV 6096
Query: 165 ALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQL 224
+L C+ A ++V+WY D L P P Y F
Sbjct: 6097 SLQCQ----VAGTPEITVSWY----------------KGDTKLRPTPEYRTYFT------ 6130
Query: 225 NKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMF-ITKKQTDQTTLRIQPAVKD 283
N + F ++ +D G+ C+A I +F I ++Q + R +KD
Sbjct: 6131 NNVATLVF----NKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFAR---QLKD 6183
Query: 284 FQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKE 343
+ + G P+ L C + S +Q W+ +G + L++D
Sbjct: 6184 IEQTV--------GLPVTLTCRLNGSA---PIQVCWYRDG-----------VLLRDD--- 6218
Query: 344 RASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQR--KQSPDS 401
LQ S + A +LKI G Y C + + T + S ++ R K+SP
Sbjct: 6219 ----ENLQTSFVDNVA-TLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFF 6273
Query: 402 HVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFVA 461
+ KP + V+ GE+ F C GA+ P+ ++W +D +
Sbjct: 6274 DI---KPVSIDVI-----------AGESADFECHVTGAQ-PMRITW---SKDNKE----- 6310
Query: 462 GMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQA 521
++ G +Y + GNT L I DSG Y C + + +
Sbjct: 6311 -------IRPGGNYTITCV-GNTP---------HLRILKVGKGDSGQYTC---QATNDVG 6350
Query: 522 RDLSWTQKISVTVKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQF 581
+D+ Q L+ S +++Q + + L C + +G ++KV
Sbjct: 6351 KDMCSAQLSVKEPPKFVKKLEASKVAKQGE-----SIQLECKI-SGSPEIKV-------- 6396
Query: 582 QPASSHIFHQLIRITHNGTIEWGNFLSRFQKKTKVSQSLFRS--QLLVHDATEEETGVYQ 639
W S + K + S S L +++A+ E++G Y
Sbjct: 6397 --------------------SWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYI 6436
Query: 640 CEVEVYDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSI 699
CE +N AS + A+T+ + S V L S+ ++C I
Sbjct: 6437 CEA---------HNGVGDASCST-----ALTVKAPPVFTQKPSPVGALK-GSDVILQCEI 6481
Query: 700 LSRSNGNLQLAIIWYFSPVST-NASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQ 758
+G ++W N+ KI T F T
Sbjct: 6482 ----SGTPPFEVVWVKDRKQVRNSKKFKI----------TSKHFDT-------------- 6513
Query: 759 DLFQLHILNVEDSDRGKYHC 778
LHILN+E SD G+YHC
Sbjct: 6514 ---SLHILNLEASDVGEYHC 6530
Score = 42.0 bits (97), Expect = 0.003
Identities = 90/384 (23%), Positives = 139/384 (36%), Gaps = 84/384 (21%)
Query: 69 EVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDE 128
+ Q+ T + S+ ++R Y + N L +++ + D+GEY C N+
Sbjct: 7981 QCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENS-- 8038
Query: 129 KYYGSYSAKTNLIVIPDTLSATMSSQTLGKEE--GEPLALTCEASKATAQHTHLSVTWYL 186
G SA T L V L + S Q +E G P+ C S + +SV+WY
Sbjct: 8039 --VGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEP----ISVSWY- 8091
Query: 187 TQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQ 246
+DG KD + +VQ + L T L+I + S GQ
Sbjct: 8092 -KDG---------KPLKD--------------SPNVQTSFL-DNTATLNIFKTDRSLAGQ 8126
Query: 247 LFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLV 306
C AT I + I + + I+ A D V +AD C V
Sbjct: 8127 YSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESAD----------FECHV 8176
Query: 307 VSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFS 366
+G P ++ W D +E S G+ Q+S L A L +
Sbjct: 8177 --TGTQP-IKVSW------------------AKDSREIRSGGKYQISYLENSA-HLTVLK 8214
Query: 367 LGPEDEGAYRC-VVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVW 425
+ D G Y C V EV K + ++ + P S TK + V
Sbjct: 8215 VDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF--------------TKRLSETVE 8260
Query: 426 EGETLAFLCKAGGAES-PLSVSWW 448
E E +F + A S P++V+W+
Sbjct: 8261 ETEGNSFKLEGRVAGSQPITVAWY 8284
Score = 37.0 bits (84), Expect = 0.095
Identities = 29/119 (24%), Positives = 50/119 (42%), Gaps = 10/119 (8%)
Query: 69 EVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDE 128
+ Q+ T + S+ ++R Y N L +K+ + D+GEY C N+
Sbjct: 6099 QCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENS-- 6156
Query: 129 KYYGSYSAKTNLIVIPDTLSATMSSQTLGKEE--GEPLALTCEASKATAQHTHLSVTWY 185
G+ S+KT + L + + Q E+ G P+ LTC + + + V WY
Sbjct: 6157 --IGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAP----IQVCWY 6209
Score = 36.2 bits (82), Expect = 0.16
Identities = 116/576 (20%), Positives = 202/576 (35%), Gaps = 143/576 (24%)
Query: 67 TQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNT 126
T +V+ TK+ + Q + G Y V +L I + KD+GEY N
Sbjct: 4597 TLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQND 4656
Query: 127 DEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWYL 186
+ S A+ N++ + S T + + +G + L C A +S+ W+
Sbjct: 4657 VGR--SSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLEC----IVAGSHPISIQWF- 4709
Query: 187 TQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQ 246
KD + +AS+ T L I +L+ +D G
Sbjct: 4710 ----------------KD---------DQEISASEKYKFSFHDNTAFLEISQLEGTDSGT 4744
Query: 247 LFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLV 306
C AT ++ +T K+ + Q + + +L P+ +
Sbjct: 4745 YTCSATN-KAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIK--- 4800
Query: 307 VSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFS 366
WF + E+ H A ++ +K+ S SL++F+
Sbjct: 4801 ------------WFKDNKEL-HSGAA-----RSVWKDDTST-------------SLELFA 4829
Query: 367 LGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWE 426
D G Y C ++ + T T S L K+ P ++KP S V+ +N
Sbjct: 4830 AKATDSGTYICQLSNDVGTAT-SKATLFVKEPPQ---FIKKP---SPVLVLRN------- 4875
Query: 427 GETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRL 486
G++ F C+ G + VSW+ + T + HG + +
Sbjct: 4876 GQSTTFECQITGTPK-IRVSWYLDGNEITAIQ---------------------KHGISFI 4913
Query: 487 EKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLESSLQVSLM 546
+ + ATFQ I+ + +SGTY C +AR+ + T S+ +K E + +
Sbjct: 4914 DGL--ATFQ--ISGARVENSGTYVC--------EARNDAGTASCSIELKVKEPPTFIREL 4961
Query: 547 SRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNF 606
+ +V+ + +L C V P VTW + +N I
Sbjct: 4962 -KPVEVVKYSDVELECEVTG-----TPPFEVTW---------------LKNNREI----- 4995
Query: 607 LSRFQKKTKVSQSLFRSQLLVHDATEEETGVYQCEV 642
R KK ++ + L + +TG YQC V
Sbjct: 4996 --RSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIV 5029
Score = 36.2 bits (82), Expect = 0.16
Identities = 28/121 (23%), Positives = 51/121 (42%), Gaps = 10/121 (8%)
Query: 67 TQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNT 126
T + ++ T + S+ ++RS Y + + N L I+K+ D GEY C N+
Sbjct: 7038 TLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNS 7097
Query: 127 DEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEE--GEPLALTCEASKATAQHTHLSVTW 184
G+ ++ L++ L + + E G P+A C + + L V+W
Sbjct: 7098 ----VGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEP----LQVSW 7149
Query: 185 Y 185
Y
Sbjct: 7150 Y 7150
Score = 36.2 bits (82), Expect = 0.16
Identities = 87/444 (19%), Positives = 156/444 (35%), Gaps = 106/444 (23%)
Query: 103 SVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGE 162
S +L I ++DAG+Y C+ N K S SA+ I+I + + + G+
Sbjct: 7922 SAILEIPSSTVEDAGQYNCYIENASGK--DSCSAQ---ILILEPPYFVKQLEPVKVSVGD 7976
Query: 163 PLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDV 222
+L C+ A + V+WY D L P Y F
Sbjct: 7977 SASLQCQ----LAGTPEIGVSWY----------------KGDTKLRPTTTYKMHFR---- 8012
Query: 223 QLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVK 282
N + F ++ +D G+ C+A + + + ++Q + Q ++
Sbjct: 8013 --NNVATLVF----NQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQ--LR 8064
Query: 283 DFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYK 342
D Q + G P+ C + SG +P + W+ +G K
Sbjct: 8065 DVQETV--------GLPVVFDCAI--SGSEP-ISVSWYKDG------------------K 8095
Query: 343 ERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSH 402
+Q S L A +L IF G Y C + + + S +++ +
Sbjct: 8096 PLKDSPNVQTSFLDNTA-TLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPF 8154
Query: 403 VHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFVAG 462
+R +VV GE+ F C G + P+ VSW R+
Sbjct: 8155 FDIRLAPVDAVV------------GESADFECHVTGTQ-PIKVSWAKDSRE--------- 8192
Query: 463 MGQDGIVQLGASYGVPSYHGNT------RLEKMDWATFQLEITFTAITDSGTYECRVSEK 516
++ G Y + SY N+ +++K D + T A+ + G C
Sbjct: 8193 ------IRSGGKYQI-SYLENSAHLTVLKVDKGDSGQY----TCYAVNEVGKDSCTAQLN 8241
Query: 517 SRNQARDLSWTQKISVTVKSLESS 540
+ + S+T+++S TV+ E +
Sbjct: 8242 IKERLIPPSFTKRLSETVEETEGN 8265
Score = 35.8 bits (81), Expect = 0.21
Identities = 62/303 (20%), Positives = 104/303 (34%), Gaps = 75/303 (24%)
Query: 215 ERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTT 274
+ AASD T L I R+ +D G C AT + D + I ++ T
Sbjct: 4151 KEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVT 4210
Query: 275 LRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGV 334
+P KD P VCL + L WF
Sbjct: 4211 ---KPGSKDV-------------LPGSAVCLKSTFQGSTPLTIRWF-------------- 4240
Query: 335 LGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQ 394
KE S G ++K ++ SL+++ + D G Y C V+ V G +
Sbjct: 4241 ----KGNKELVSGGSCYITKEALES-SLELYLVKTSDSGTYTCKVSNV----AGGVEC-- 4289
Query: 395 RKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQ 454
+++ +++PA + Q++ +G+ CK G P+ ++W+ R+
Sbjct: 4290 -----SANLFVKEPA---TFVEKLEPSQLLKKGDATQLACKVTGT-PPIKITWFANDREI 4340
Query: 455 TQPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVS 514
+ S H + +E +T L +T I DSG Y C
Sbjct: 4341 KE---------------------SSKHRMSFVE----STAVLRLTDVGIEDSGEYMCEAQ 4375
Query: 515 EKS 517
++
Sbjct: 4376 NEA 4378
Score = 34.7 bits (78), Expect = 0.47
Identities = 65/347 (18%), Positives = 125/347 (36%), Gaps = 85/347 (24%)
Query: 102 NSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEG 161
N +L +S L ++D G Y C N +G+ + LI+I D + +
Sbjct: 3604 NKHILELSNLTIQDRGVYSCKASNK----FGADICQAELIII-DKPHFIKELEPVQSAIN 3658
Query: 162 EPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASD 221
+ + L C+ + ++VTW ++DG + + KD+ + + ++ A +
Sbjct: 3659 KKVHLECQVD----EDRKVTVTW--SKDG------QKLPPGKDYKI----CFEDKIATLE 3702
Query: 222 VQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAV 281
+ L KL + + S++ G C AT +++P
Sbjct: 3703 IPLAKLKDSGTYVC---TASNEAGSSSCSATVTVREP----------------------- 3736
Query: 282 KDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDY 341
F + L G+ L C + S P +Q WF N
Sbjct: 3737 PSFVKKVDPSYLMLPGESARLHCKLKGS---PVIQVTWFKNN------------------ 3775
Query: 342 KERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDS 401
KE + +++ + +A L I + ED G+Y C + + + S +++ ++ P S
Sbjct: 3776 KELSESNTVRMYFVNSEAI-LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE--PPS 3832
Query: 402 HVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSWW 448
+ +PA + G C+ G P +SW+
Sbjct: 3833 FIKTLEPAD-------------IVRGTNALLQCEVSGT-GPFEISWF 3865
Score = 34.3 bits (77), Expect = 0.62
Identities = 31/138 (22%), Positives = 54/138 (39%), Gaps = 20/138 (14%)
Query: 73 ISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYG 132
+S +D + + +++ D V R +G L + ++++DAGE + +
Sbjct: 12219 LSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD------- 12271
Query: 133 SYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGG 192
+ NL V + T + EEG L CE S+ A+ V W+
Sbjct: 12272 -FKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAK-----VKWF------- 12318
Query: 193 SQATEIISLSKDFILVPG 210
TEI+ K I+ G
Sbjct: 12319 KNGTEILKSKKYEIVADG 12336
Score = 33.5 bits (75), Expect = 1.0
Identities = 82/387 (21%), Positives = 135/387 (34%), Gaps = 89/387 (22%)
Query: 65 NPTQEVQIIS----TKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYE 120
NP VQ+ + T + + + SG S L + + D+G Y
Sbjct: 4780 NPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYI 4839
Query: 121 CHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHL 180
C N G+ ++K L V S L G+ C+ + +
Sbjct: 4840 CQLSND----VGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPK----I 4891
Query: 181 SVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQ 240
V+WYL G++ T I FI G TF++S R++
Sbjct: 4892 RVSWYLD----GNEITAIQKHGISFID--------------------GLATFQISGARVE 4927
Query: 241 SSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPL 300
+S G CEA + + I+ VK+ + E KP+
Sbjct: 4928 NS--GTYVCEA---------------RNDAGTASCSIELKVKE------PPTFIRELKPV 4964
Query: 301 ELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAF 360
E+V D +L+ E+ V LKN+ + R+S+ ++ F
Sbjct: 4965 EVV-----KYSDVELE-------CEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVS--VF 5010
Query: 361 SLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNK 420
+L I P D G Y+C+V+ GS S + V L++P S + +N
Sbjct: 5011 NLHITKCDPSDTGEYQCIVS----NEGGSC-------SCSTRVALKEPP--SFIKKIENT 5057
Query: 421 QQVVWEGETLAFLCKAGGAESPLSVSW 447
V+ T F G+ P+S++W
Sbjct: 5058 TTVLKSSAT--FQSTVAGS-PPISITW 5081
Score = 33.1 bits (74), Expect = 1.4
Identities = 26/117 (22%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 69 EVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDE 128
E + + +++ + +R G Y GN+ L I K+ D+G+Y C N
Sbjct: 6291 ECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVG 6350
Query: 129 KYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWY 185
K SA+ ++ P + +S+ ++GE + L C+ S + + V+W+
Sbjct: 6351 K--DMCSAQLSVKEPPKFVKKLEASKV--AKQGESIQLECKISGS----PEIKVSWF 6399
Score = 32.7 bits (73), Expect = 1.8
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 89 VRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLS 148
+RSG Y +Q + V L I K DAGEY+C T+E SA+ L P +
Sbjct: 4433 LRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRV--TNEVGSSICSARVTLREPPSFIK 4490
Query: 149 ATMSSQTL 156
S+ +L
Sbjct: 4491 KIESTSSL 4498
Score = 32.7 bits (73), Expect = 1.8
Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 72 IISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYY 131
++S A ++ +R + G LHI +Q+ DAGEY C +++
Sbjct: 11141 LVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKE-- 11198
Query: 132 GSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASK 172
+ +AK + +P T+ + + +G+PL L+CE +K
Sbjct: 11199 KTSTAKLVVEELPVRFVKTLEEE-VTVVKGQPLYLSCELNK 11238
Score = 31.6 bits (70), Expect = 4.0
Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 10/99 (10%)
Query: 73 ISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYG 132
I+ + S+ T+++ D + + G+ L + Q+KD G Y G
Sbjct: 8681 INYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRL--------VCG 8732
Query: 133 SYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEAS 171
+ A L VI + TL +EG+ +TC+ S
Sbjct: 8733 PHIASAKLTVIEPAWERHLQDVTL--KEGQTCTMTCQFS 8769
Score = 31.2 bits (69), Expect = 5.2
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 8/33 (24%)
Query: 749 QKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVE 781
+ FHT +HILNV+ SD G+YHC +
Sbjct: 5568 KNFHTS--------IHILNVDTSDIGEYHCKAQ 5592
Score = 30.8 bits (68), Expect = 6.8
Identities = 56/282 (19%), Positives = 92/282 (32%), Gaps = 57/282 (20%)
Query: 100 QGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGK- 158
+ N+++L + K M DAG Y C N + T+ IVI + + Q L
Sbjct: 8301 KNNTLVLQVRKAGMNDAGLYTCKVSND-----AGSALCTSSIVIKEPKKPPVFDQHLTPV 8355
Query: 159 --EEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTER 216
EGE + L+C GS+ I L + P +
Sbjct: 8356 TVSEGEYVQLSCHVQ--------------------GSEPIRIQWLKAGREIKPSDRCSFS 8395
Query: 217 FAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLR 276
FA+ T L + + +D G C+A+ + D T +T K
Sbjct: 8396 FASG----------TAVLELRDVAKADSGDYVCKASN-VAGSDTTKSKVTIKDKPAVAPA 8444
Query: 277 IQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLG 336
+ A D ++ ++ + G DP W
Sbjct: 8445 TKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW----------------- 8487
Query: 337 LKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCV 378
K +++ G + + + G +A L+I D G YRCV
Sbjct: 8488 TKGKWRQLNQGGRVFIHQKGDEA-KLEIRDTTKTDSGLYRCV 8528
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 45.8 bits (107), Expect = 2e-04
Identities = 79/353 (22%), Positives = 125/353 (35%), Gaps = 90/353 (25%)
Query: 106 LHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLA 165
L + +Q++D+GEY C + + + + I+ P T+ + TL E +
Sbjct: 955 LVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIYPRD-EVTLIAVTL-----ECVV 1008
Query: 166 LTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLN 225
L CE S+ A V WY +DG + +E + L +D
Sbjct: 1009 LMCELSREDA-----PVRWY--KDGLEVEESEALVLERD--------------------- 1040
Query: 226 KLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQ 285
GP RL + Q D G+ C+A + F T T + PA +
Sbjct: 1041 --GPRC-RLVLPAAQPEDGGEFVCDA-------GDDSAFFTVTVTAPPERIVHPAARSLD 1090
Query: 286 VNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERA 345
++ F +EL C V +G Q W+ +G E+ DA
Sbjct: 1091 LH------FGAPGRVELRCEVAPAGS----QVRWYKDGLEVEASDA-------------- 1126
Query: 346 SQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHL 405
LQ+ GP +L + PED G Y C R ++ +V L
Sbjct: 1127 ----LQLGAEGPTR-TLTLPHAQPEDAGEYVCET---------------RHEAITFNVIL 1166
Query: 406 RKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPE 458
+P + + + T V GE + C+ A +P V W H R + E
Sbjct: 1167 AEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAP--VVWSHNGRPVQEGE 1217
Score = 36.2 bits (82), Expect = 0.16
Identities = 69/307 (22%), Positives = 105/307 (34%), Gaps = 76/307 (24%)
Query: 73 ISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYG 132
+S +DA + V + V G L + Q +D GE+ C + +
Sbjct: 1013 LSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTV 1072
Query: 133 SYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGG 192
+ +A IV P S + G+ E L CE + A +Q V WY +DG
Sbjct: 1073 TVTAPPERIVHPAARSLDLHFGAPGRVE-----LRCEVAPAGSQ-----VRWY--KDG-- 1118
Query: 193 SQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEAT 252
E A+ +QL GPT L++ Q D G+ CE
Sbjct: 1119 ---------------------LEVEASDALQLGAEGPTR-TLTLPHAQPEDAGEYVCETR 1156
Query: 253 EWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSL-FAEGKPLELVCLVVSSGR 311
E F + +P V+ + T L A G+P+ L C + +G
Sbjct: 1157 H------EAITF--------NVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGA 1202
Query: 312 DPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGE-LQVSKLGPKAFSLKIFSLGPE 370
+W NG + +GE L++ GP+ L I + GP
Sbjct: 1203 PV----VWSHNGRPV-------------------QEGEGLELHAEGPRRV-LCIQAAGPA 1238
Query: 371 DEGAYRC 377
G Y C
Sbjct: 1239 HAGLYTC 1245
>gi|8393638 F11 receptor precursor [Homo sapiens]
Length = 299
Score = 45.4 bits (106), Expect = 3e-04
Identities = 55/242 (22%), Positives = 85/242 (35%), Gaps = 48/242 (19%)
Query: 12 LLLTKLSIGQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQEVQ 71
+LL L++G V + + E PV + C +G P +W
Sbjct: 19 ILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSP---RVEWKF----------- 64
Query: 72 IISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYY 131
+ Y ++ + Y +RV + + +D G Y C Y
Sbjct: 65 ---DQGDTTRLVCYNNKITAS--YEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGGNSY 119
Query: 132 GSYSAKTNLIVIPDTLSATM-SSQTLGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDG 190
G K ++V P + + SS T+G LTC + + TW+
Sbjct: 120 GEVKVKLIVLVPPSKPTVNIPSSATIGNRA----VLTCSEQDGSPPSEY---TWF----- 167
Query: 191 GGSQATEIISLSKDFILVP-GPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFC 249
KD I++P P T F+ S LN PTT L + L +SD G+ C
Sbjct: 168 ------------KDGIVMPTNPKSTRAFSNSSYVLN---PTTGELVFDPLSASDTGEYSC 212
Query: 250 EA 251
EA
Sbjct: 213 EA 214
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 45.4 bits (106), Expect = 3e-04
Identities = 57/256 (22%), Positives = 100/256 (39%), Gaps = 55/256 (21%)
Query: 211 PLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQT 270
PL RF QL + ++S+ + SD+G+ FC+ ++ Q
Sbjct: 91 PLKDSRF-----QLLNFSSSELKVSLTNVSISDEGRYFCQ------------LYTDPPQE 133
Query: 271 DQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHID 330
TT+ + ++ ++I D+ EG+ +E+ C ++S P WF TE+
Sbjct: 134 SYTTITVLVPPRNLMIDIQKDTA-VEGEEIEVNCTAMAS--KPATTIRWFKGNTELK--- 187
Query: 331 AGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTR-TGS 389
+ +D SQ L+V K ED+G V+ +V TG+
Sbjct: 188 GKSEVEEWSDMYTVTSQLMLKVHK---------------EDDGVP--VICQVEHPAVTGN 230
Query: 390 WQV---LQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVS 446
Q L+ + P H+ + P Q + EG+ L C+A G P+ V+
Sbjct: 231 LQTQRYLEVQYKPQVHIQMTYPL-----------QGLTREGDALELTCEAIGKPQPVMVT 279
Query: 447 WWHIPRDQTQPEFVAG 462
W + + Q ++G
Sbjct: 280 WVRVDDEMPQHAVLSG 295
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 45.4 bits (106), Expect = 3e-04
Identities = 57/256 (22%), Positives = 100/256 (39%), Gaps = 55/256 (21%)
Query: 211 PLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQT 270
PL RF QL + ++S+ + SD+G+ FC+ ++ Q
Sbjct: 91 PLKDSRF-----QLLNFSSSELKVSLTNVSISDEGRYFCQ------------LYTDPPQE 133
Query: 271 DQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHID 330
TT+ + ++ ++I D+ EG+ +E+ C ++S P WF TE+
Sbjct: 134 SYTTITVLVPPRNLMIDIQKDTA-VEGEEIEVNCTAMAS--KPATTIRWFKGNTELK--- 187
Query: 331 AGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTR-TGS 389
+ +D SQ L+V K ED+G V+ +V TG+
Sbjct: 188 GKSEVEEWSDMYTVTSQLMLKVHK---------------EDDGVP--VICQVEHPAVTGN 230
Query: 390 WQV---LQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVS 446
Q L+ + P H+ + P Q + EG+ L C+A G P+ V+
Sbjct: 231 LQTQRYLEVQYKPQVHIQMTYPL-----------QGLTREGDALELTCEAIGKPQPVMVT 279
Query: 447 WWHIPRDQTQPEFVAG 462
W + + Q ++G
Sbjct: 280 WVRVDDEMPQHAVLSG 295
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 44.3 bits (103), Expect = 6e-04
Identities = 159/766 (20%), Positives = 259/766 (33%), Gaps = 230/766 (30%)
Query: 25 TVQKGP--LFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQEVQIISTKDAAFSY 82
T+Q G L EG PV++ C +G+ PS WS ++ ++IST A FS
Sbjct: 982 TIQHGQQILSTIEGIPVTLPCKASGNPKPS---VIWS--------KKGELISTSSAKFSA 1030
Query: 83 AVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIV 142
G +YV G +++GEY C NT Y + + V
Sbjct: 1031 GA------DGSLYVVSPGG------------EESGEYVCTATNTAG--YAKRKVQLTVYV 1070
Query: 143 IPDTLSATMS-SQTLGKE----EGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATE 197
P SQ E GE + L CE +TW ++ T+
Sbjct: 1071 RPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPP----IITW--------AKETQ 1118
Query: 198 IISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQD 257
+IS P +T + S + I ++SD G C AT +
Sbjct: 1119 LISPFS-------PRHTFLPSGS-------------MKITETRTSDSGMYLCVATNIAGN 1158
Query: 258 PDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQG 317
+ K +IQ K +V + G+ +++ C + + L
Sbjct: 1159 VTQA-----VKLNVHVPPKIQRGPKHLKVQV--------GQRVDIPC----NAQGTPLPV 1201
Query: 318 IWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRC 377
I + G +D GE VS P +L I P D G Y C
Sbjct: 1202 ITWSKGGSTMLVD-----------------GEHHVSN--PDG-TLSIDQATPSDAGIYTC 1241
Query: 378 VVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAG 437
V + T ++ Q P + L P +T +++V + + F C A
Sbjct: 1242 VATNI--AGTDETEITLHVQEPPTVEDLEPP------YNTTFQERVA--NQRIEFPCPAK 1291
Query: 438 GAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLE 497
G P ++ W H R+ T E + +DG + + AS V Y
Sbjct: 1292 GTPKP-TIKWLHNGRELTGREPGISILEDGTLLVIAS--VTPY----------------- 1331
Query: 498 ITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLESSLQVSLMSRQPQVMLTNT 557
D+G Y C ++ R + + +K E VS++ Q LTN
Sbjct: 1332 -------DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ----LTNL 1380
Query: 558 FDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNFLSRFQKKTKVS 617
F C V S + + W + +++T + TI+ N K+
Sbjct: 1381 F---CEVEGTPSPI-----IMW---------YKDNVQVTESSTIQTVN-------NGKIL 1416
Query: 618 QSLFRSQLLVHDATEEETGVYQCE-VEVYDRNSLYNNRPPRASAISHPLRIAVTLPESKL 676
+ LFR AT E+ G Y C+ + + + Y N I V +P + +
Sbjct: 1417 K-LFR-------ATPEDAGRYSCKAINIAGTSQKYFN-------------IDVLVPPTII 1455
Query: 677 KVNSRSQVQELSINSNTDIECSILSRSNGNLQLAIIWY--FSPVSTNASWLKILEMDQTN 734
N ++V + +N + +EC + G I W+ P+ +++L+ Q
Sbjct: 1456 GTNFPNEV-SVVLNRDVALECQV----KGTPFPDIHWFKDGKPLFLGDPNVELLDRGQV- 1509
Query: 735 VIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAV 780
LH+ N +D+G+Y C V
Sbjct: 1510 ----------------------------LHLKNARRNDKGRYQCTV 1527
Score = 38.9 bits (89), Expect = 0.025
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 106 LHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLA 165
LHI ++Q++D GEY C N + KT +V+ + Q L EG P+
Sbjct: 945 LHIERVQLQDGGEYTCVASNV-----AGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVT 999
Query: 166 LTCEAS 171
L C+AS
Sbjct: 1000 LPCKAS 1005
Score = 38.9 bits (89), Expect = 0.025
Identities = 71/294 (24%), Positives = 110/294 (37%), Gaps = 64/294 (21%)
Query: 102 NSVLLHISKLQMKDAGEYECHTPNT---DEKYYGSYSAKTNLIVIPDTLSATMSSQTLGK 158
N +L I Q+ D G Y C NT +KY+ N+ V P + S+ L
Sbjct: 2924 NGRILQILNTQITDIGRYVCVAENTAGSAKKYF-----NLNVHVPPSVIGP--KSENLTV 2976
Query: 159 EEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFA 218
++LTCE S ++W + + I L+ + ++VPG
Sbjct: 2977 VVNNFISLTCEVSGFPPP----DLSWLKNE--------QPIKLNTNTLIVPG-------- 3016
Query: 219 ASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQ 278
G T L I R + SD G+ C A I E+ K+ T+ +
Sbjct: 3017 ---------GRT---LQIIRAKVSDGGEYTCIA---INQAGES------KKKFSLTVYVP 3055
Query: 279 PAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNG---TEIAHIDA---G 332
P++KD + EG + L C S P W+ NG TE H++ G
Sbjct: 3056 PSIKDHDSESLSVVNVREGTSVSLEC---ESNAVPPPVITWYKNGRMITESTHVEILADG 3112
Query: 333 GVLGLKNDYKERASQ---GELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVM 383
+L +K Q + V+ K F L ++ + P EG R V+ E +
Sbjct: 3113 QMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY-VPPSIEGPEREVIVETI 3165
Score = 37.4 bits (85), Expect = 0.073
Identities = 50/239 (20%), Positives = 82/239 (34%), Gaps = 52/239 (21%)
Query: 341 YKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPD 400
YK+ E + LK+F PED G Y C + T + + P
Sbjct: 1395 YKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNI--DVLVPP 1452
Query: 401 SHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFV 460
+ + P SVV++ +A C+ G P + W+
Sbjct: 1453 TIIGTNFPNEVSVVLN-----------RDVALECQVKGTPFP-DIHWF------------ 1488
Query: 461 AGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQ 520
G P + G+ +E +D L + D G Y+C VS + Q
Sbjct: 1489 -------------KDGKPLFLGDPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQ 1534
Query: 521 ARDLSWTQKISVTVKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTW 579
A+D+ T I ++K + +S V++ + L C R L +P +TW
Sbjct: 1535 AKDIKLTIYIPPSIKGGNVTTDIS-------VLINSLIKLECETRG----LPMP-AITW 1581
Score = 36.6 bits (83), Expect = 0.12
Identities = 56/240 (23%), Positives = 94/240 (39%), Gaps = 61/240 (25%)
Query: 211 PLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEA-TEWIQDPDETWMFITKKQ 269
P+++ F+ S + + G L I L +SD+G CEA ++ + ET + +T
Sbjct: 833 PIFSRPFSVSSISQLRTGA----LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLV 888
Query: 270 TDQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHI 329
+ I P+V + EG+ L L C +++ P+ + W N +
Sbjct: 889 AP--LIGISPSVANV----------IEGQQLTLPCTLLAGNPIPERR--WIKNSAML--- 931
Query: 330 DAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGS 389
L+N Y S G L + ++ +D G Y CV + V T +
Sbjct: 932 -------LQNPYITVRSDGSLHIERVQL------------QDGGEYTCVASNVAGTNNKT 972
Query: 390 WQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVV--WEGETLAFLCKAGGAESPLSVSW 447
V+ VH V+ + ++ QQ++ EG + CKA G P SV W
Sbjct: 973 TSVV---------VH--------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKP-SVIW 1014
Score = 36.2 bits (82), Expect = 0.16
Identities = 65/353 (18%), Positives = 129/353 (36%), Gaps = 84/353 (23%)
Query: 43 CNVTGHQGPSEQHFQWSVYLPTN----PTQEVQIISTKDAAF------SYAVYTQRV--- 89
C G S++ F +VY+P + ++ + +++ ++ S AV +
Sbjct: 3035 CIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWY 3094
Query: 90 RSGDVYVE----RVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPD 145
++G + E + + +LHI K ++ D G+Y C N + ++ + +P
Sbjct: 3095 KNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLN---VYVPP 3151
Query: 146 TLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDF 205
++ + + + P+ LTC+A+ ++ W
Sbjct: 3152 SIEGP-EREVIVETISNPVTLTCDATGIPPP----TIAWLKNH----------------- 3189
Query: 206 ILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFI 265
+R SD ++ +L I R Q SD G C A+ ++ + + F+
Sbjct: 3190 ---------KRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN-MEGKAQKYYFL 3239
Query: 266 TKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTE 325
++++ P+V I +D G+ +ELVC + P +Q W +G
Sbjct: 3240 --------SIQVPPSVAG--AEIPSDVSVLLGENVELVC-NANGIPTPLIQ--WLKDGKP 3286
Query: 326 IAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCV 378
IA GE + ++ +L I+ D G Y CV
Sbjct: 3287 IA-------------------SGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320
Score = 33.9 bits (76), Expect = 0.80
Identities = 35/146 (23%), Positives = 55/146 (37%), Gaps = 38/146 (26%)
Query: 496 LEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLESSLQVSLMSRQPQVMLT 555
L +T I+D+G Y C + + RD+ + + E ++ V+++
Sbjct: 2068 LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNV---------SVLIS 2118
Query: 556 NTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNFLSRFQKKTK 615
+L C SD P T+TW H L+ KK
Sbjct: 2119 QAVELLC-----QSDAIPPPTLTWLKDG------HPLL------------------KKPG 2149
Query: 616 VSQSLFRSQLLVHDATEEETGVYQCE 641
+S S RS L + DA ++TG Y CE
Sbjct: 2150 LSISENRSVLKIEDAQVQDTGRYTCE 2175
Score = 33.5 bits (75), Expect = 1.0
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 3/73 (4%)
Query: 99 VQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGK 158
+ N +L I Q++D G Y C N K +Y+ I +P + + L
Sbjct: 2152 ISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVN---IWVPPNIGGSDELTQLTV 2208
Query: 159 EEGEPLALTCEAS 171
EG ++L CE+S
Sbjct: 2209 IEGNLISLLCESS 2221
Score = 33.5 bits (75), Expect = 1.0
Identities = 71/346 (20%), Positives = 123/346 (35%), Gaps = 89/346 (25%)
Query: 106 LHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIV-IPDTLSA--TMSSQTLGKEEGE 162
L I + ++ D GEY C N G K +L V +P ++ + S + EG
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQA----GESKKKFSLTVYVPPSIKDHDSESLSVVNVREGT 3075
Query: 163 PLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDV 222
++L CE++ +TWY G TE + IL G +
Sbjct: 3076 SVSLECESNAVPPP----VITWYKN----GRMITESTHVE---ILADGQM---------- 3114
Query: 223 QLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVK 282
L I++ + SD GQ C A D+ + + + P+++
Sbjct: 3115 -----------LHIKKAEVSDTGQYVCRAINVAGRDDKNF---------HLNVYVPPSIE 3154
Query: 283 DFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYK 342
+ + +++ P+ L C + I + LKN +
Sbjct: 3155 GPEREVIVETI---SNPVTLTC--------------------DATGIPPPTIAWLKNHKR 3191
Query: 343 -ERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDS 401
E + E+++ G K L+I D G Y C+ + M+ + + L Q P S
Sbjct: 3192 IENSDSLEVRILSGGSK---LQIARSQHSDSGNYTCIASN-MEGKAQKYYFLSI-QVPPS 3246
Query: 402 HVHLRKPAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSW 447
P+ SV++ GE + +C A G +PL + W
Sbjct: 3247 VAGAEIPSDVSVLL-----------GENVELVCNANGIPTPL-IQW 3280
Score = 33.1 bits (74), Expect = 1.4
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 14/85 (16%)
Query: 105 LLHISKLQMKDAGEYECHTPN----TDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEE 160
+L + + + D G Y C N TD+KY S A P + S + + E
Sbjct: 2347 ILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP------PSIIGNHRSPENISVVE 2400
Query: 161 GEPLALTCEASKATAQHTHLSVTWY 185
++LTCEAS S+TW+
Sbjct: 2401 KNSVSLTCEASGIPLP----SITWF 2421
Score = 33.1 bits (74), Expect = 1.4
Identities = 35/160 (21%), Positives = 66/160 (41%), Gaps = 28/160 (17%)
Query: 43 CNVTGHQGPSEQHFQWSVYLPTNP-----TQEVQIISTKDAAFSYAVYTQR--------V 89
C + G +H+ V+ P N T+E+ ++ K ++ S A T +
Sbjct: 3413 CVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVL--KGSSTSMACITDGTPAPSMAWL 3470
Query: 90 RSG-----DVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIP 144
R G D ++ V + ++L + K + +D+G+Y C N + + K ++ P
Sbjct: 3471 RDGQPLGLDAHLT-VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILK---VLEP 3526
Query: 145 DTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTW 184
++ + + + PL LTC AS A +TW
Sbjct: 3527 PHINGSEEHEEISVIVNNPLELTCIASGIPAP----KMTW 3562
Score = 31.6 bits (70), Expect = 4.0
Identities = 42/175 (24%), Positives = 62/175 (35%), Gaps = 30/175 (17%)
Query: 31 LFRAEGYPVSIG---CNVTGHQGPSEQHFQWSVYLP-----TNPTQEVQIISTKDAAFSY 82
LFRA P G C G S+++F V +P TN EV ++ +D A
Sbjct: 1418 LFRAT--PEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALEC 1475
Query: 83 AVYT------------QRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKY 130
V + + GD VE + VL H+ + D G Y+C N K
Sbjct: 1476 QVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVL-HLKNARRNDKGRYQCTVSNAAGKQ 1534
Query: 131 YGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWY 185
I IP ++ + + + L CE T ++TWY
Sbjct: 1535 AKDIKL---TIYIPPSIKGGNVTTDISVLINSLIKLECE----TRGLPMPAITWY 1582
Score = 30.4 bits (67), Expect = 8.9
Identities = 32/148 (21%), Positives = 52/148 (35%), Gaps = 36/148 (24%)
Query: 763 LHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTE 822
L I+ + SD G+Y C ++ GE K + P K S+
Sbjct: 3020 LQIIRAKVSDGGEYTCIAI----------NQAGESKKKFSLTVYVPPSIKDHDSESLSVV 3069
Query: 823 NVTEHREVAIRCSLESVGSSATLYSVMWYWNRENSGSKLLVHLQHDGLLEYGEEGLRRHL 882
NV E V++ C +V + WY N +++ H +L G+
Sbjct: 3070 NVREGTSVSLECESNAVPPPV----ITWYKN-----GRMITESTHVEILADGQ------- 3113
Query: 883 HCYRSSSTDFVLKLHQVEMEDAGMYWCR 910
+L + + E+ D G Y CR
Sbjct: 3114 ----------MLHIKKAEVSDTGQYVCR 3131
>gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
Length = 508
Score = 43.1 bits (100), Expect = 0.001
Identities = 54/211 (25%), Positives = 85/211 (40%), Gaps = 49/211 (23%)
Query: 242 SDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFA--EGKP 299
SD G FC + +F+ K ++ +++Q FQ + S F EG P
Sbjct: 75 SDSGNYFCST--------KGQLFLWDKTSNIVKIKVQEL---FQRPVLTASSFQPIEGGP 123
Query: 300 LELVCLVVSSGR--DPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGP 357
+ L C S + D QLQ +F VLG +S ELQ+S
Sbjct: 124 VSLKCETRLSPQRLDVQLQFCFFRENQ---------VLG-----SGWSSSPELQIS---- 165
Query: 358 KAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMST 417
++ ED G+Y C K T + ++ RKQS S +H+++ +V +
Sbjct: 166 --------AVWSEDTGSYWC------KAETVTHRI--RKQSLQSQIHVQRIPISNVSLEI 209
Query: 418 KNKQQVVWEGETLAFLCKAGGAESPLSVSWW 448
+ V EG+ L LC G ++ SW+
Sbjct: 210 RAPGGQVTEGQKLILLCSVAGGTGNVTFSWY 240
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 42.4 bits (98), Expect = 0.002
Identities = 78/348 (22%), Positives = 119/348 (34%), Gaps = 113/348 (32%)
Query: 36 GYPVSIGCNVTGHQGPSEQHFQWS----VYLPTNPTQEVQIISTKDAAFSYAVYTQRVRS 91
G V++ C+ TGH P W+ LP +P + S
Sbjct: 356 GESVTLECSATGHPPP---RISWTRGDRTPLPVDPRVNI------------------TPS 394
Query: 92 GDVYVERV-QGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSAT 150
G +Y++ V QG D+GEY C N + + T I++ T
Sbjct: 395 GGLYIQNVVQG-------------DSGEYACSATNNIDSVHA-----TAFIIVQALPQFT 436
Query: 151 MSSQTLGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPG 210
++ Q EG+ + CEA + W GGSQ +S+ + ++
Sbjct: 437 VTPQDRVVIEGQTVDFQCEAKGNPPP----VIAW----TKGGSQ----LSVDRRHLV--- 481
Query: 211 PLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQT 270
L T R+S L DQGQ C+A I Q
Sbjct: 482 ----------------LSSGTLRISGVALH--DQGQYECQAVN-----------IIGSQK 512
Query: 271 DQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHID 330
L +QP V +I +D+ G ++L C SS +P+ W +G ++
Sbjct: 513 VVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPC---SSQGEPEPAITWNKDGVQVTE-- 567
Query: 331 AGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCV 378
G+ +S P+ F L I +GP D G Y CV
Sbjct: 568 ----------------SGKFHIS---PEGF-LTINDVGPADAGRYECV 595
>gi|21450677 hypothetical protein LOC196740 isoform 2 [Homo sapiens]
Length = 191
Score = 41.2 bits (95), Expect = 0.005
Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 4/112 (3%)
Query: 426 EGETLAFLCKAGGA---ESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYHG 482
EGE LC +S L+V W+ +Q + M + +VQ ++ +
Sbjct: 38 EGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRR 97
Query: 483 NTRL-EKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVT 533
RL E+ A ++L + +D G Y CRV E SR++ + +W+ S T
Sbjct: 98 RLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQEISRHRNKWTAWSNGSSAT 149
Score = 38.1 bits (87), Expect = 0.043
Identities = 24/107 (22%), Positives = 53/107 (49%), Gaps = 9/107 (8%)
Query: 692 NTDIECSILSRSNGNLQLAIIWYFSPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKF 751
N + C + + + LA+ W+F+ S ++ +++M + V++ F ++++
Sbjct: 41 NATLLCHVSQKRRKDSLLAVRWFFAH-SFDSQEALMVKMTKLRVVQYYGNFSRSAKRRRL 99
Query: 752 HT-EKVSQDLFQLHILNVEDSDRGKYHCAVEE-------WLLSTNGT 790
E+ L++L +L ++ SD+G Y C V+E W +NG+
Sbjct: 100 RLLEEQRGALYRLSVLTLQPSDQGHYVCRVQEISRHRNKWTAWSNGS 146
Score = 33.5 bits (75), Expect = 1.0
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 10/99 (10%)
Query: 160 EGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAA 219
EGE L C S+ + + L+V W+ +A ++ ++K ++ Y F+
Sbjct: 38 EGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEAL-MVKMTKLRVVQ----YYGNFSR 92
Query: 220 SDVQ-----LNKLGPTTFRLSIERLQSSDQGQLFCEATE 253
S + L + +RLS+ LQ SDQG C E
Sbjct: 93 SAKRRRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQE 131
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 39.7 bits (91), Expect = 0.015
Identities = 63/303 (20%), Positives = 113/303 (37%), Gaps = 73/303 (24%)
Query: 97 ERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTL 156
ER+Q + L I+ L + D+G Y+C N + Y + + L PD + + ++
Sbjct: 362 ERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRV-LASAPDFSKSPVKKKSF 420
Query: 157 GKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKD-FILVPGPLYTE 215
+ G+ + + C+ + +++W + TE + SK F+L G
Sbjct: 421 VQVGGD-IVIGCKPN----AFPRAAISW--------KRGTETLRQSKRIFLLEDG----- 462
Query: 216 RFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTL 275
L I + SD G C AT T I K ++T +
Sbjct: 463 -----------------SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVK---ERTVI 502
Query: 276 RIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQ--GIWFFNGTEIAHIDAGG 333
+ P+ D V G+ + L C V DP ++ +WFFN G
Sbjct: 503 TVPPSKMDVTV----------GESIVLPCQV---SHDPSIEVVFVWFFN---------GD 540
Query: 334 VLGLKNDYKERASQGELQVSKLGPKAF-SLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQV 392
V+ LK +G ++G ++ L I ++ G Y C V +++ + +
Sbjct: 541 VIDLK--------KGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADI 592
Query: 393 LQR 395
+ R
Sbjct: 593 IVR 595
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 39.3 bits (90), Expect = 0.019
Identities = 45/178 (25%), Positives = 66/178 (37%), Gaps = 14/178 (7%)
Query: 36 GYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQEVQIISTKDAAFSYAVYTQRVRSGDVY 95
G + C G G W+ QE+ ++ +K Y RV
Sbjct: 45 GQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPP 104
Query: 96 VERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQT 155
+ G SVLL D GEYEC GS+ A+ L V+ L +
Sbjct: 105 RNPLDG-SVLLR--NAVQADEGEYECRVSTFPA---GSFQARLRLRVLVPPLPSLNPGPA 158
Query: 156 LGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGS----QATEIISLSKDFILVP 209
L + +G LA +C A + A SVTW G S + + +++ +F LVP
Sbjct: 159 LEEGQGLTLAASCTAEGSPAP----SVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVP 212
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 38.9 bits (89), Expect = 0.025
Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 8/109 (7%)
Query: 67 TQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNT 126
T +Q +K A + ++ +R GD Y R G L I L + D GEY C
Sbjct: 3818 TAVLQCELSKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVC--G 3875
Query: 127 DEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATA 175
E+ + + + V + L Q+L EEG L CE S+ TA
Sbjct: 3876 QERTSATLTVRAPQPVFREPL------QSLQAEEGSTATLQCELSEPTA 3918
Score = 35.4 bits (80), Expect = 0.28
Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 12/104 (11%)
Query: 72 IISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYY 131
++S+ A + +R GD Y R +G + L + L+ +D+G Y C +
Sbjct: 3207 VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCS--------F 3258
Query: 132 GSYSAKTNLIVIPDTLSATMSSQTLGKE--EGEPLALTCEASKA 173
G + L V L A + KE EG L CE SKA
Sbjct: 3259 GDQTTSATLTV--TALPAQFIGKLRNKEATEGATATLRCELSKA 3300
Score = 34.3 bits (77), Expect = 0.62
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 87 QRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDT 146
+ +R GD Y+ R +G L I L M DAGEY C SA + +P
Sbjct: 3486 ENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQE------RTSATLTIRALPAR 3539
Query: 147 LSATMSSQTLGKEEGEPLALTCEASKA 173
+ +Q EG L CE + A
Sbjct: 3540 FIEDVKNQE--AREGATAVLQCELNSA 3564
Score = 33.9 bits (76), Expect = 0.80
Identities = 74/337 (21%), Positives = 112/337 (33%), Gaps = 98/337 (29%)
Query: 99 VQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGK 158
++G L I +L DAG Y C GS + T + V ++ T Q
Sbjct: 2518 LEGQMAELRILRLMPADAGVYRCQA--------GSAHSSTEVTVEAREVTVTGPLQDAEA 2569
Query: 159 EEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFA 218
E + +CE S H V W L PLY + F
Sbjct: 2570 TEEGWASFSCELS-----HEDEEVEWSLNGM---------------------PLYNDSFH 2603
Query: 219 ASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQ 278
+++ G L ++ +Q +D G + + + T+ R++
Sbjct: 2604 ----EISHKG-RRHTLVLKSIQRADAGIVRASSLKV-----------------STSARLE 2641
Query: 279 PAVKDFQVNITADSLFAEGK-PLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGL 337
VK D L AE + L L C V DP+ +W +G ++ D
Sbjct: 2642 VRVKPVVFLKALDDLSAEERGTLALQCEV----SDPEAHVVWRKDGVQLGPSD------- 2690
Query: 338 KNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQ 397
K D+ A L + + PED G Y C V GS + R +
Sbjct: 2691 KYDFLHTAGTR------------GLVVHDVSPEDAGLYTCHV--------GSEETRARVR 2730
Query: 398 SPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLC 434
D HV + K + K V EGE+ +F C
Sbjct: 2731 VHDLHVGITK----------RLKTMEVLEGESCSFEC 2757
Score = 33.1 bits (74), Expect = 1.4
Identities = 26/87 (29%), Positives = 31/87 (35%), Gaps = 8/87 (9%)
Query: 86 TQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPD 145
++ +R GD Y R G L I L M D GEY C G L V
Sbjct: 3573 SETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSC--------VCGQERTSAMLTVRAL 3624
Query: 146 TLSATMSSQTLGKEEGEPLALTCEASK 172
+ T + EG L CE SK
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELSK 3651
Score = 32.7 bits (73), Expect = 1.8
Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 13/87 (14%)
Query: 98 RVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLG 157
R+QG + L + LQ +D GEY C GS + L V + Q
Sbjct: 3938 RLQGCTAELVLQDLQREDTGEYTCTC--------GSQATSATLTVTAAPVRFLRELQHQE 3989
Query: 158 KEEGEPLALTCEASKATAQHTHLSVTW 184
+EG L CE S+A A SV W
Sbjct: 3990 VDEGGTAHLCCELSRAGA-----SVEW 4011
Score = 32.3 bits (72), Expect = 2.3
Identities = 133/644 (20%), Positives = 224/644 (34%), Gaps = 163/644 (25%)
Query: 73 ISTKDAAFSYAVYTQRVRSGDVYV-----------ERVQGNSVLLHISKLQMKDAGEYEC 121
I+ + A S +Y VYV +VQG + L ++ +DAGE +
Sbjct: 2213 IAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQF 2272
Query: 122 HTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQ-TLGKEEGEPLALTCEASKATAQHTHL 180
N + + A+ + +P TL + + + K G L C+ S+A+AQ
Sbjct: 2273 VAENAESR------AQLRVKELPVTLVRPLRDKIAMEKHRG---VLECQVSRASAQ---- 2319
Query: 181 SVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQ 240
V W+ GSQ L PGP Y SD KL + E
Sbjct: 2320 -VRWF-----KGSQE-----------LQPGPKYE---LVSDGLYRKLIISDVHAEDEDTY 2359
Query: 241 SSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPL 300
+ D G + A ++++ T I + D T + PA + + +I
Sbjct: 2360 TCDAGDVKTSAQFFVEEQSIT---IVRGLQDVTVMEPAPAWFECETSI------------ 2404
Query: 301 ELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKND-YKERASQGELQVSKLGPKA 359
S R P+ W T + AGG +GL+ + R + GP
Sbjct: 2405 -------PSVRPPK----WLLGKTV---LQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVH 2450
Query: 360 FSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLR--------KPAAR 411
F++ + + R VV+++ VL R P + L+ +PA +
Sbjct: 2451 FTV------GKSRSSARLVVSDIP-------VVLTRPLEPKTGRELQSVVLSCDFRPAPK 2497
Query: 412 SV-------VMSTKNKQQVVWEGETL-------------AFLCKAGGAESPLSVSWWHIP 451
+V +S K ++ EG+ + C+AG A S V+
Sbjct: 2498 AVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEARE 2557
Query: 452 RDQTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYEC 511
T P A ++G AS+ H + E+++W+ + + + +
Sbjct: 2558 VTVTGPLQDAEATEEG----WASFSCELSHED---EEVEWSLNGMPLYNDSFHE------ 2604
Query: 512 RVSEKSRNQARDLSWTQKISVTVKSLESSLQVSLMSR-----QPQVMLTNTFDLSCVVRA 566
+S K R L Q+ + SSL+VS +R +P V L DLS R
Sbjct: 2605 -ISHKGRRHTLVLKSIQRADAGIVR-ASSLKVSTSARLEVRVKPVVFLKALDDLSAEERG 2662
Query: 567 GYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNFLSRFQKKTKVSQSLFRSQLL 626
L + + +H+ + ++ G K + L+
Sbjct: 2663 -------TLALQCEVSDPEAHV------VWRKDGVQLGP-----SDKYDFLHTAGTRGLV 2704
Query: 627 VHDATEEETGVYQCEVEVYDRNSLYNNRPPRASAISHPLRIAVT 670
VHD + E+ G+Y C V + RA H L + +T
Sbjct: 2705 VHDVSPEDAGLYTCHV---------GSEETRARVRVHDLHVGIT 2739
Score = 32.3 bits (72), Expect = 2.3
Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 8/99 (8%)
Query: 75 TKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSY 134
+K A + ++ +R GD Y R G L I L M DA EY C G
Sbjct: 3298 SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC--------VCGEE 3349
Query: 135 SAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKA 173
+L + P + EG L CE SKA
Sbjct: 3350 RTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELSKA 3388
Score = 31.6 bits (70), Expect = 4.0
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 87 QRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDT 146
+ +R GD + R G+ L I L + DAGEY C SA + +P
Sbjct: 3750 ETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQE------RTSATLTVRALPAR 3803
Query: 147 LSATMSSQTLGKEEGEPLALTCEASKA 173
+ +Q EG L CE SKA
Sbjct: 3804 FIEDVKNQE--AREGATAVLQCELSKA 3828
Score = 31.2 bits (69), Expect = 5.2
Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 89 VRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLS 148
+ +G Y R QG + L I +L+ KD GEY C T G +L V ++
Sbjct: 4109 LHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVT--------GGQKTAASLRVTEPEVT 4160
Query: 149 ATMSSQTLGKEEGEPLALTCEASKATA 175
E + +CE S+A A
Sbjct: 4161 IVRGLVDAEVTADEDVEFSCEVSRAGA 4187
Score = 31.2 bits (69), Expect = 5.2
Identities = 44/180 (24%), Positives = 66/180 (36%), Gaps = 33/180 (18%)
Query: 23 EVTVQKGPL--FRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPT----NPTQEVQIISTK 76
EV V+ G + R +G V+ H G Q +V P P Q+VQ+ +
Sbjct: 4206 EVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPLQDVQLSEGQ 4265
Query: 77 DAAFSY---------------AVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYEC 121
DA+F V Q D+ VE QG LL + K+ ++DAG
Sbjct: 4266 DASFQCRLSRASGQEARWALGGVPLQANEMNDITVE--QGTLHLLTLHKVTLEDAGTVSF 4323
Query: 122 HTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASK-ATAQHTHL 180
H + +AK ++ + + A EG C+ S+ A HT L
Sbjct: 4324 HVGTCSSEAQLKVTAKNTVVRGLENVEAL---------EGGEALFECQLSQPEVAAHTWL 4374
Score = 31.2 bits (69), Expect = 5.2
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
Query: 361 SLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQR-----KQSPDSHVHLRKPAARSVVM 415
+L+I S+ ED G Y ++ M S ++L R ++ P S VH + R +
Sbjct: 5317 TLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLER 5376
Query: 416 STKNKQQVVWEGETLAFLCKAGGAESPLSVSW 447
T K V +G ++ F K G P +V W
Sbjct: 5377 FTPKK---VKKGSSITFSVKVEGRPVP-TVHW 5404
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 38.9 bits (89), Expect = 0.025
Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 8/109 (7%)
Query: 67 TQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNT 126
T +Q +K A + ++ +R GD Y R G L I L + D GEY C
Sbjct: 3818 TAVLQCELSKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVC--G 3875
Query: 127 DEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKATA 175
E+ + + + V + L Q+L EEG L CE S+ TA
Sbjct: 3876 QERTSATLTVRAPQPVFREPL------QSLQAEEGSTATLQCELSEPTA 3918
Score = 35.4 bits (80), Expect = 0.28
Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 12/104 (11%)
Query: 72 IISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYY 131
++S+ A + +R GD Y R +G + L + L+ +D+G Y C +
Sbjct: 3207 VLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCS--------F 3258
Query: 132 GSYSAKTNLIVIPDTLSATMSSQTLGKE--EGEPLALTCEASKA 173
G + L V L A + KE EG L CE SKA
Sbjct: 3259 GDQTTSATLTV--TALPAQFIGKLRNKEATEGATATLRCELSKA 3300
Score = 34.3 bits (77), Expect = 0.62
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 87 QRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDT 146
+ +R GD Y+ R +G L I L M DAGEY C SA + +P
Sbjct: 3486 ENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQE------RTSATLTIRALPAR 3539
Query: 147 LSATMSSQTLGKEEGEPLALTCEASKA 173
+ +Q EG L CE + A
Sbjct: 3540 FIEDVKNQE--AREGATAVLQCELNSA 3564
Score = 33.9 bits (76), Expect = 0.80
Identities = 74/337 (21%), Positives = 112/337 (33%), Gaps = 98/337 (29%)
Query: 99 VQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGK 158
++G L I +L DAG Y C GS + T + V ++ T Q
Sbjct: 2518 LEGQMAELRILRLMPADAGVYRCQA--------GSAHSSTEVTVEAREVTVTGPLQDAEA 2569
Query: 159 EEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFA 218
E + +CE S H V W L PLY + F
Sbjct: 2570 TEEGWASFSCELS-----HEDEEVEWSLNGM---------------------PLYNDSFH 2603
Query: 219 ASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQ 278
+++ G L ++ +Q +D G + + + T+ R++
Sbjct: 2604 ----EISHKG-RRHTLVLKSIQRADAGIVRASSLKV-----------------STSARLE 2641
Query: 279 PAVKDFQVNITADSLFAEGK-PLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGL 337
VK D L AE + L L C V DP+ +W +G ++ D
Sbjct: 2642 VRVKPVVFLKALDDLSAEERGTLALQCEV----SDPEAHVVWRKDGVQLGPSD------- 2690
Query: 338 KNDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQ 397
K D+ A L + + PED G Y C V GS + R +
Sbjct: 2691 KYDFLHTAGTR------------GLVVHDVSPEDAGLYTCHV--------GSEETRARVR 2730
Query: 398 SPDSHVHLRKPAARSVVMSTKNKQQVVWEGETLAFLC 434
D HV + K + K V EGE+ +F C
Sbjct: 2731 VHDLHVGITK----------RLKTMEVLEGESCSFEC 2757
Score = 33.1 bits (74), Expect = 1.4
Identities = 26/87 (29%), Positives = 31/87 (35%), Gaps = 8/87 (9%)
Query: 86 TQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPD 145
++ +R GD Y R G L I L M D GEY C G L V
Sbjct: 3573 SETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSC--------VCGQERTSAMLTVRAL 3624
Query: 146 TLSATMSSQTLGKEEGEPLALTCEASK 172
+ T + EG L CE SK
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELSK 3651
Score = 32.7 bits (73), Expect = 1.8
Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 13/87 (14%)
Query: 98 RVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLG 157
R+QG + L + LQ +D GEY C GS + L V + Q
Sbjct: 3938 RLQGCTAELVLQDLQREDTGEYTCTC--------GSQATSATLTVTAAPVRFLRELQHQE 3989
Query: 158 KEEGEPLALTCEASKATAQHTHLSVTW 184
+EG L CE S+A A SV W
Sbjct: 3990 VDEGGTAHLCCELSRAGA-----SVEW 4011
Score = 32.3 bits (72), Expect = 2.3
Identities = 133/644 (20%), Positives = 224/644 (34%), Gaps = 163/644 (25%)
Query: 73 ISTKDAAFSYAVYTQRVRSGDVYV-----------ERVQGNSVLLHISKLQMKDAGEYEC 121
I+ + A S +Y VYV +VQG + L ++ +DAGE +
Sbjct: 2213 IAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQF 2272
Query: 122 HTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQ-TLGKEEGEPLALTCEASKATAQHTHL 180
N + + A+ + +P TL + + + K G L C+ S+A+AQ
Sbjct: 2273 VAENAESR------AQLRVKELPVTLVRPLRDKIAMEKHRG---VLECQVSRASAQ---- 2319
Query: 181 SVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQ 240
V W+ GSQ L PGP Y SD KL + E
Sbjct: 2320 -VRWF-----KGSQE-----------LQPGPKYE---LVSDGLYRKLIISDVHAEDEDTY 2359
Query: 241 SSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPL 300
+ D G + A ++++ T I + D T + PA + + +I
Sbjct: 2360 TCDAGDVKTSAQFFVEEQSIT---IVRGLQDVTVMEPAPAWFECETSI------------ 2404
Query: 301 ELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKND-YKERASQGELQVSKLGPKA 359
S R P+ W T + AGG +GL+ + R + GP
Sbjct: 2405 -------PSVRPPK----WLLGKTV---LQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVH 2450
Query: 360 FSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLR--------KPAAR 411
F++ + + R VV+++ VL R P + L+ +PA +
Sbjct: 2451 FTV------GKSRSSARLVVSDIP-------VVLTRPLEPKTGRELQSVVLSCDFRPAPK 2497
Query: 412 SV-------VMSTKNKQQVVWEGETL-------------AFLCKAGGAESPLSVSWWHIP 451
+V +S K ++ EG+ + C+AG A S V+
Sbjct: 2498 AVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEARE 2557
Query: 452 RDQTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYEC 511
T P A ++G AS+ H + E+++W+ + + + +
Sbjct: 2558 VTVTGPLQDAEATEEG----WASFSCELSHED---EEVEWSLNGMPLYNDSFHE------ 2604
Query: 512 RVSEKSRNQARDLSWTQKISVTVKSLESSLQVSLMSR-----QPQVMLTNTFDLSCVVRA 566
+S K R L Q+ + SSL+VS +R +P V L DLS R
Sbjct: 2605 -ISHKGRRHTLVLKSIQRADAGIVR-ASSLKVSTSARLEVRVKPVVFLKALDDLSAEERG 2662
Query: 567 GYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNFLSRFQKKTKVSQSLFRSQLL 626
L + + +H+ + ++ G K + L+
Sbjct: 2663 -------TLALQCEVSDPEAHV------VWRKDGVQLGP-----SDKYDFLHTAGTRGLV 2704
Query: 627 VHDATEEETGVYQCEVEVYDRNSLYNNRPPRASAISHPLRIAVT 670
VHD + E+ G+Y C V + RA H L + +T
Sbjct: 2705 VHDVSPEDAGLYTCHV---------GSEETRARVRVHDLHVGIT 2739
Score = 32.3 bits (72), Expect = 2.3
Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 8/99 (8%)
Query: 75 TKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSY 134
+K A + ++ +R GD Y R G L I L M DA EY C G
Sbjct: 3298 SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC--------VCGEE 3349
Query: 135 SAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASKA 173
+L + P + EG L CE SKA
Sbjct: 3350 RTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELSKA 3388
Score = 31.6 bits (70), Expect = 4.0
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 87 QRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDT 146
+ +R GD + R G+ L I L + DAGEY C SA + +P
Sbjct: 3750 ETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQE------RTSATLTVRALPAR 3803
Query: 147 LSATMSSQTLGKEEGEPLALTCEASKA 173
+ +Q EG L CE SKA
Sbjct: 3804 FIEDVKNQE--AREGATAVLQCELSKA 3828
Score = 31.2 bits (69), Expect = 5.2
Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 89 VRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLS 148
+ +G Y R QG + L I +L+ KD GEY C T G +L V ++
Sbjct: 4109 LHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVT--------GGQKTAASLRVTEPEVT 4160
Query: 149 ATMSSQTLGKEEGEPLALTCEASKATA 175
E + +CE S+A A
Sbjct: 4161 IVRGLVDAEVTADEDVEFSCEVSRAGA 4187
Score = 31.2 bits (69), Expect = 5.2
Identities = 44/180 (24%), Positives = 66/180 (36%), Gaps = 33/180 (18%)
Query: 23 EVTVQKGPL--FRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPT----NPTQEVQIISTK 76
EV V+ G + R +G V+ H G Q +V P P Q+VQ+ +
Sbjct: 4206 EVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPLQDVQLSEGQ 4265
Query: 77 DAAFSY---------------AVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYEC 121
DA+F V Q D+ VE QG LL + K+ ++DAG
Sbjct: 4266 DASFQCRLSRASGQEARWALGGVPLQANEMNDITVE--QGTLHLLTLHKVTLEDAGTVSF 4323
Query: 122 HTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQTLGKEEGEPLALTCEASK-ATAQHTHL 180
H + +AK ++ + + A EG C+ S+ A HT L
Sbjct: 4324 HVGTCSSEAQLKVTAKNTVVRGLENVEAL---------EGGEALFECQLSQPEVAAHTWL 4374
Score = 31.2 bits (69), Expect = 5.2
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
Query: 361 SLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQR-----KQSPDSHVHLRKPAARSVVM 415
+L+I S+ ED G Y ++ M S ++L R ++ P S VH + R +
Sbjct: 5317 TLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLER 5376
Query: 416 STKNKQQVVWEGETLAFLCKAGGAESPLSVSW 447
T K V +G ++ F K G P +V W
Sbjct: 5377 FTPKK---VKKGSSITFSVKVEGRPVP-TVHW 5404
>gi|139948432 adlican [Homo sapiens]
Length = 2828
Score = 38.9 bits (89), Expect = 0.025
Identities = 50/208 (24%), Positives = 75/208 (36%), Gaps = 40/208 (19%)
Query: 35 EGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQEVQIISTKDAAFSYAVYTQRVRSGDV 94
EG P + CNV + PS W LP + + D+ FS
Sbjct: 493 EGGPCQLSCNVKASESPS---IFW--VLPDGSILKAPM-DDPDSKFSIL----------- 535
Query: 95 YVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSSQ 154
+S L I ++ D+G Y+C DE Y L+ P T A +
Sbjct: 536 -------SSGWLRIKSMEPSDSGLYQCIAQVRDEMDRMVYRV---LVQSPSTQPAEKDTV 585
Query: 155 TLGKEEGEPLALTCEASKATAQHTHLSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYT 214
T+GK GE + L C A H ++W L ++ + S ++L G L
Sbjct: 586 TIGKNPGESVTLPCNALAIPEAH----LSWILP---NRRIINDLANTSHVYMLPNGTLSI 638
Query: 215 ERFAASD------VQLNKLGPTTFRLSI 236
+ SD V +N+ G F + I
Sbjct: 639 PKVQVSDSGYYRCVAVNQQGADHFTVGI 666
Score = 33.9 bits (76), Expect = 0.80
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 13/91 (14%)
Query: 361 SLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNK 420
+L I +L P+D G Y CV A ++ + + Q +++++ AA + + T +
Sbjct: 2106 TLYIRNLAPKDSGRYECVAANLVGSARRTVQ-----------LNVQRAAANARITGTSPR 2154
Query: 421 QQVVWEGETLAFLCKAGGAESPLSVSWWHIP 451
+ V G TL C A G P + W +P
Sbjct: 2155 RTDVRYGGTLKLDCSASGDPWPRIL--WRLP 2183
>gi|142976733 surface glycoprotein, Ig superfamily member [Homo
sapiens]
Length = 1264
Score = 38.5 bits (88), Expect = 0.033
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 8/123 (6%)
Query: 34 AEGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQEVQIISTKDAAFSYAVYTQRVRSGD 93
A+G V++ CN +G P + + + ++P+Q ++ S K S + +
Sbjct: 417 ADGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRK----SQLSRPEGLNLEP 472
Query: 94 VYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKTNLIVIPDTLSATMSS 153
VY Q + LHI + + AG+Y C N +G+ A+ +L+V+P + +
Sbjct: 473 VYFVLSQAGASSLHIQAVTQEHAGKYICEAANE----HGTTQAEASLMVVPFETNTKAET 528
Query: 154 QTL 156
TL
Sbjct: 529 VTL 531
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,169,652
Number of Sequences: 37866
Number of extensions: 1758035
Number of successful extensions: 7456
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 161
Number of HSP's that attempted gapping in prelim test: 5840
Number of HSP's gapped (non-prelim): 1595
length of query: 1021
length of database: 18,247,518
effective HSP length: 112
effective length of query: 909
effective length of database: 14,006,526
effective search space: 12731932134
effective search space used: 12731932134
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.