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Search of human proteins with 157502205
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
(549 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157502205 TBC1 domain family, member 3G [Homo sapiens] 1153 0.0
gi|226693407 TBC1 domain family, member 3H [Homo sapiens] 1151 0.0
gi|183583563 TBC1 domain family, member 3D [Homo sapiens] 1151 0.0
gi|90577185 TBC1 domain family member 3C [Homo sapiens] 1150 0.0
gi|183583565 TBC1 domain family, member 3 [Homo sapiens] 1149 0.0
gi|183583567 TBC1 domain family, member 3E [Homo sapiens] 1149 0.0
gi|14149985 TBC1 domain family, member 3F [Homo sapiens] 1146 0.0
gi|149999613 TBC1 domain family, member 3B [Homo sapiens] 1144 0.0
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 845 0.0
gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ... 495 e-140
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 243 3e-64
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 243 3e-64
gi|148235002 TBC1 domain family, member 26 [Homo sapiens] 238 1e-62
gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo ... 186 5e-47
gi|239756790 PREDICTED: similar to hCG1991532 [Homo sapiens] 181 1e-45
gi|239756750 PREDICTED: similar to TBC1 domain family, member 28... 171 2e-42
gi|151108489 TBC1 domain family, member 28 [Homo sapiens] 171 2e-42
gi|239751314 PREDICTED: hypothetical protein XP_002347802 [Homo ... 154 2e-37
gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo sapi... 130 3e-30
gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo sapi... 130 4e-30
gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo sapi... 130 4e-30
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 107 3e-23
gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 105 8e-23
gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 105 1e-22
gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 88 2e-17
gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 86 1e-16
gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 86 1e-16
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 85 1e-16
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 85 1e-16
gi|7661586 TBC1 domain family, member 29 [Homo sapiens] 84 4e-16
>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
Length = 549
Score = 1153 bits (2982), Expect = 0.0
Identities = 549/549 (100%), Positives = 549/549 (100%)
Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL
Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
Query: 541 ESSQFPPGF 549
ESSQFPPGF
Sbjct: 541 ESSQFPPGF 549
>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
Length = 549
Score = 1151 bits (2978), Expect = 0.0
Identities = 548/549 (99%), Positives = 549/549 (100%)
Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
MDVVEVAGSWWAQEREDIIMKYEKGH+AGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL
Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
Query: 541 ESSQFPPGF 549
ESSQFPPGF
Sbjct: 541 ESSQFPPGF 549
>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
Length = 549
Score = 1151 bits (2977), Expect = 0.0
Identities = 547/549 (99%), Positives = 549/549 (100%)
Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
KLKNPGRYQIMKEKGKRSSEHIQRIDRD+SGTLRKH+FFRDRYGTKQRELLHILLAYEEY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180
Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL
Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
Query: 541 ESSQFPPGF 549
ESSQFPPGF
Sbjct: 541 ESSQFPPGF 549
>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
Length = 549
Score = 1150 bits (2974), Expect = 0.0
Identities = 548/549 (99%), Positives = 548/549 (99%)
Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
HVVATSQ KTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI
Sbjct: 241 HVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL
Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
Query: 541 ESSQFPPGF 549
ESSQFPPGF
Sbjct: 541 ESSQFPPGF 549
>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
Length = 549
Score = 1149 bits (2973), Expect = 0.0
Identities = 546/549 (99%), Positives = 549/549 (100%)
Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
KLKNPGRYQIMKEKGKRSSEHIQRIDRD+SGTLRKH+FFRDRYGTKQRELLHILLAYEEY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180
Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRK+GDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPP 360
Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL
Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
Query: 541 ESSQFPPGF 549
ESSQFPPGF
Sbjct: 541 ESSQFPPGF 549
>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
Length = 549
Score = 1149 bits (2973), Expect = 0.0
Identities = 546/549 (99%), Positives = 549/549 (100%)
Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
KLKNPGRYQIMKEKGKRSSEHIQRIDRD+SGTLRKH+FFRDRYGTKQRELLHILLAYEEY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180
Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRK+GDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPP 360
Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL
Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
Query: 541 ESSQFPPGF 549
ESSQFPPGF
Sbjct: 541 ESSQFPPGF 549
>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
Length = 549
Score = 1146 bits (2965), Expect = 0.0
Identities = 544/549 (99%), Positives = 548/549 (99%)
Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLN EEM
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEM 120
Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
KLKNPGRYQIMKEKGK+SSEHIQRIDRD+SGTLRKH+FFRDRYGTKQRELLHILLAYEEY
Sbjct: 121 KLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180
Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRK+GDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPP 360
Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL
Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
Query: 541 ESSQFPPGF 549
ESSQFPPGF
Sbjct: 541 ESSQFPPGF 549
>gi|149999613 TBC1 domain family, member 3B [Homo sapiens]
Length = 549
Score = 1144 bits (2959), Expect = 0.0
Identities = 546/549 (99%), Positives = 546/549 (99%)
Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
NPEVGYCRDLSHIAALFLLY PEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYFPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
HVVATSQ KTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI
Sbjct: 241 HVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540
RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQ APTSGPCLCGLHL
Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQYAPTSGPCLCGLHL 540
Query: 541 ESSQFPPGF 549
ESSQFPPGF
Sbjct: 541 ESSQFPPGF 549
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 845 bits (2184), Expect = 0.0
Identities = 407/500 (81%), Positives = 440/500 (88%), Gaps = 1/500 (0%)
Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
MD+VE A S AQER+DI+MKY+KGHRAGLPEDKGP+P N+++D GI+HETELPP+
Sbjct: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPV-GINSSIDRFGILHETELPPV 59
Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
TAREAK+IRRE++R SKW++MLG+WE YK S KLIDR YKG+PMNIRGP+WSVLLNI+E+
Sbjct: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
KLKNPGRYQIMKE+GKRSSEHI ID D+ TLR H+FFRDRYG KQREL +ILLAY EY
Sbjct: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
NPEVGYCRDLSHI ALFLLYLPEEDAFWALVQLLASERHSL GFHSPNGGTVQGLQDQQE
Sbjct: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQE 239
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
HVV SQPKTM HQDK+ LCGQC+ LGCL+R LIDGISLGLTLRLWDVYLVEGEQ LMPI
Sbjct: 240 HVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPI 299
Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
T IA KVQQKRL KTSRCG WAR N+F DTWA ++DTVLKHLRAS KKLTRKQGDLPPP
Sbjct: 300 TSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359
Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
AK EQGS A RPVPASRGGKTLCKG RQAPPGPPA+F RPI SASPP A R STPCPGGA
Sbjct: 360 AKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGA 419
Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
VREDTYPVGTQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+ GPWF HYDF SCWV
Sbjct: 420 VREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWV 479
Query: 481 RAISQEDQLAPCWQAEHPAE 500
RAISQEDQLA CWQAEH E
Sbjct: 480 RAISQEDQLATCWQAEHCGE 499
>gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
[Homo sapiens]
Length = 424
Score = 495 bits (1275), Expect = e-140
Identities = 230/240 (95%), Positives = 232/240 (96%)
Query: 310 KRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 369
KRLTKTSRCGPWARF NRFVD WARD+DTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA
Sbjct: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
Query: 370 SRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG 429
SRPVPASRGGKTLCKGDRQAPPGPPARFP PIWSASPPRAPRSSTPCPGGAVREDTYPVG
Sbjct: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
Query: 430 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQL 489
TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDV PWFR YDFRQSCWVRAISQEDQ
Sbjct: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
Query: 490 APCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 549
A CWQAEHPAERVRSAF+APSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
Sbjct: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 424
Score = 311 bits (798), Expect = 8e-85
Identities = 144/165 (87%), Positives = 157/165 (95%)
Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
MDVVEV GSWWAQEREDIIMKYEKGHRAGLPEDKGPKPF SYNNN+DH G+ HETELPPL
Sbjct: 1 MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
TARE KQIRREISRKSKWV MLG+W+ YK+SRKLIDRAY+G+PMNIRGPMWSVLLNIEE+
Sbjct: 61 TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGT 165
KLKNPGRYQIMKEKGKRSSEHIQ++D D+SGTLR+H+FFRDRYGT
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGT 165
>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
Length = 828
Score = 243 bits (621), Expect = 3e-64
Identities = 147/434 (33%), Positives = 216/434 (49%), Gaps = 25/434 (5%)
Query: 12 AQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRRE 71
AQER +I+ KY++G E + Y D G +HE ELP +Q E
Sbjct: 12 AQERAEIVAKYDRGREGAEIEPWEDADYLVYKVT-DRFGFLHEEELPDHNVAVERQKHLE 70
Query: 72 ISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131
I R +KW+ ML WEKYK++ K R YKG+P+ +RG +W++LL I +MK + Y +
Sbjct: 71 IERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKL 130
Query: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
K + + S I++ID D++ T R H+ FRDRYG KQ+ L H+L AY YN EVGYC+ +S
Sbjct: 131 KHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMS 190
Query: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251
I AL L+Y+ EEDAFWALV+L + +H++ GF + Q+ E ++ K
Sbjct: 191 QITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLK 250
Query: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKR 311
H D +++ + + +D L LR+WD+Y+ EGE+ L ++ K+ +K
Sbjct: 251 QHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKH 310
Query: 312 LTKTSRCGPWARFCNRFVDTWARD----EDTVLKHLRASMKKLTRKQGDLPPPAK----P 363
L K S F +T A+D +D V++ L+ SM +L R + DLP P K P
Sbjct: 311 LMKLS----MEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYP 366
Query: 364 EQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVRE 423
++ P S G L G R G P SP + R + P
Sbjct: 367 KKPLGQLPPELQSWGVHHLSNGQRSV--GRP----------SPLASGRRESGAPHRRHEH 414
Query: 424 DTYPVGTQGVPSPA 437
+P G P A
Sbjct: 415 SPHPQSRTGTPERA 428
>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
Length = 845
Score = 243 bits (621), Expect = 3e-64
Identities = 147/434 (33%), Positives = 216/434 (49%), Gaps = 25/434 (5%)
Query: 12 AQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRRE 71
AQER +I+ KY++G E + Y D G +HE ELP +Q E
Sbjct: 29 AQERAEIVAKYDRGREGAEIEPWEDADYLVYKVT-DRFGFLHEEELPDHNVAVERQKHLE 87
Query: 72 ISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131
I R +KW+ ML WEKYK++ K R YKG+P+ +RG +W++LL I +MK + Y +
Sbjct: 88 IERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKL 147
Query: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
K + + S I++ID D++ T R H+ FRDRYG KQ+ L H+L AY YN EVGYC+ +S
Sbjct: 148 KHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMS 207
Query: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251
I AL L+Y+ EEDAFWALV+L + +H++ GF + Q+ E ++ K
Sbjct: 208 QITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLK 267
Query: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKR 311
H D +++ + + +D L LR+WD+Y+ EGE+ L ++ K+ +K
Sbjct: 268 QHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKH 327
Query: 312 LTKTSRCGPWARFCNRFVDTWARD----EDTVLKHLRASMKKLTRKQGDLPPPAK----P 363
L K S F +T A+D +D V++ L+ SM +L R + DLP P K P
Sbjct: 328 LMKLS----MEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYP 383
Query: 364 EQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVRE 423
++ P S G L G R G P SP + R + P
Sbjct: 384 KKPLGQLPPELQSWGVHHLSNGQRSV--GRP----------SPLASGRRESGAPHRRHEH 431
Query: 424 DTYPVGTQGVPSPA 437
+P G P A
Sbjct: 432 SPHPQSRTGTPERA 445
>gi|148235002 TBC1 domain family, member 26 [Homo sapiens]
Length = 250
Score = 238 bits (606), Expect = 1e-62
Identities = 122/206 (59%), Positives = 148/206 (71%), Gaps = 5/206 (2%)
Query: 18 IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
II KYE+GHRAG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
Query: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
+KW ML DW KY+S++KL R YK +P+ +RG WS+LL+I+ +K +NPG+Y++MKEKG
Sbjct: 76 NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195
KRSS I I D+S TL+KHM F R+G KQ+EL IL+AY YNPEVGY RDLS I A
Sbjct: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195
Query: 196 LFLLYLPEEDAFWALVQLLASERHSL 221
+ LL LPEEDAFWAL QLLA ERHSL
Sbjct: 196 ILLLCLPEEDAFWALTQLLAGERHSL 221
>gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo
sapiens]
Length = 279
Score = 186 bits (472), Expect = 5e-47
Identities = 105/209 (50%), Positives = 122/209 (58%), Gaps = 22/209 (10%)
Query: 279 LGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDT 338
+GL R + G PI + K L K SR G WARF ++F TWA D D
Sbjct: 79 VGLPRRRSGLVSRAGHSDAEPIPHVTQMKVGKHLMKASRSGLWARFQDQFPQTWALDSDA 138
Query: 339 VLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASR-GGKTLCKGDRQAPPGPPARF 397
VL+HL+AS+ +KP+QGSSA RP AS G KTLCKG RQAPPGP A F
Sbjct: 139 VLRHLQASVL------------SKPKQGSSAPRPELASPCGRKTLCKGSRQAPPGPQAHF 186
Query: 398 PRPIWSASPPRAPRSSTPCPGGAVREDTYPVG-TQGVPSPALAQGGPQGSWRFLQWNSMP 456
+ IWSASPP P TPCP VG +QGVP A AQGGP+ SWR+LQWNS+P
Sbjct: 187 QQCIWSASPPWVPLPFTPCP--------VLVGLSQGVPRLAPAQGGPRVSWRYLQWNSLP 238
Query: 457 RLPTDLDVEGPWFRHYDFRQSCWVRAISQ 485
+LP D DV PWF HYDF Q CW R S+
Sbjct: 239 QLPMDSDVVSPWFPHYDFEQGCWARVPSK 267
>gi|239756790 PREDICTED: similar to hCG1991532 [Homo sapiens]
Length = 167
Score = 181 bits (460), Expect = 1e-45
Identities = 97/174 (55%), Positives = 111/174 (63%), Gaps = 22/174 (12%)
Query: 314 KTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPV 373
K SR G WARF ++F TWA D D VL+HL+AS+ +KP+QGSSA RP
Sbjct: 2 KASRSGLWARFQDQFPQTWALDSDAVLRHLQASVL------------SKPKQGSSAPRPE 49
Query: 374 PASR-GGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG-TQ 431
AS G KTLCKG RQAPPGP A F + IWSASPP P TPCP VG +Q
Sbjct: 50 LASPCGRKTLCKGSRQAPPGPQAHFQQRIWSASPPWVPLPFTPCP--------VLVGLSQ 101
Query: 432 GVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQ 485
GVP A AQGGP+ SWR+LQWNS+P+LP D DV PWF HYDF Q CW R S+
Sbjct: 102 GVPRLAPAQGGPRVSWRYLQWNSLPQLPMDSDVVSPWFPHYDFEQGCWARVPSK 155
>gi|239756750 PREDICTED: similar to TBC1 domain family, member 28
[Homo sapiens]
Length = 234
Score = 171 bits (432), Expect = 2e-42
Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)
Query: 18 IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
II KYE+GHRAG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 43 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPHVSALEVKQRRKESKRT 99
Query: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
+KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159
Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182
KRSS I I D+S TL+KHM F R+G KQ+EL IL+AY YNP
Sbjct: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206
>gi|151108489 TBC1 domain family, member 28 [Homo sapiens]
Length = 210
Score = 171 bits (432), Expect = 2e-42
Identities = 89/167 (53%), Positives = 115/167 (68%), Gaps = 5/167 (2%)
Query: 18 IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75
II KYE+GHRAG D G + R Y NN LGIVHE ELP ++A E KQ R+E R
Sbjct: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
Query: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
+KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG
Sbjct: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135
Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182
KRSS I I D+S TL+KHM F R+G KQ+EL IL+AY YNP
Sbjct: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182
>gi|239751314 PREDICTED: hypothetical protein XP_002347802 [Homo
sapiens]
Length = 179
Score = 154 bits (389), Expect = 2e-37
Identities = 93/190 (48%), Positives = 108/190 (56%), Gaps = 27/190 (14%)
Query: 300 ITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDE--DTVLKHLRASMKKLTRKQGDL 357
+ R AFKVQ+ + T C W + A+ + TV L +S
Sbjct: 1 MARTAFKVQRSKST----CAQWGLGSSGVRPRLAQGQLPHTVPMFLCSS----------- 45
Query: 358 PPPAKPEQGSSASRPVPASR-GGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPC 416
P AKP+QGSSA RP AS G KTLCKG RQAPPGP A F + IWSASPP P TPC
Sbjct: 46 PEEAKPKQGSSAPRPELASPCGRKTLCKGSRQAPPGPQAHFQQCIWSASPPWVPLPFTPC 105
Query: 417 PGGAVREDTYPVG-TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFR 475
P VG +QGVP A AQGGP+ SWR+LQWNS+P+LP D DV PWF HYDF
Sbjct: 106 P--------VLVGLSQGVPRLAPAQGGPRVSWRYLQWNSLPQLPMDSDVVSPWFPHYDFE 157
Query: 476 QSCWVRAISQ 485
Q CW R S+
Sbjct: 158 QGCWARVPSK 167
>gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo
sapiens]
Length = 339
Score = 130 bits (327), Expect = 3e-30
Identities = 91/217 (41%), Positives = 121/217 (55%), Gaps = 22/217 (10%)
Query: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242
EVGY RDLS A+ LLYLPEEDAFW V A+ R PN ++ L QE V
Sbjct: 56 EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
Query: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302
+ S PK M K+ LC + S L L++ +DG S GLTLRLWDV ++EGEQ L +
Sbjct: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
Query: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362
+FK+ ++ L K S W F R +WA ++++VL++L+ SMK+LT+K DLP P
Sbjct: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223
Query: 363 PEQGSSASRPVPA----SRGGKTLC----KGDRQAPP 391
Q +A R A S+ GK C GD +A P
Sbjct: 224 LLQ--NAHRCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
>gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo
sapiens]
Length = 617
Score = 130 bits (326), Expect = 4e-30
Identities = 88/215 (40%), Positives = 118/215 (54%), Gaps = 18/215 (8%)
Query: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242
EVGY RDLS A+ LLYLPEEDAFW V A+ R PN ++ L QE V
Sbjct: 186 EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 234
Query: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302
+ S PK M K+ LC + S L L++ +DG S GLTLRLWDV ++EGEQ L +
Sbjct: 235 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 294
Query: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362
+FK+ ++ L K S W F R +WA ++++VL++L+ SMK+LT+K DLP P
Sbjct: 295 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 353
Query: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391
Q + S+ GK C GD +A P
Sbjct: 354 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 388
>gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo
sapiens]
Length = 339
Score = 130 bits (326), Expect = 4e-30
Identities = 88/215 (40%), Positives = 118/215 (54%), Gaps = 18/215 (8%)
Query: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242
EVGY RDLS A+ LLYLPEEDAFW V A+ R PN ++ L QE V
Sbjct: 56 EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
Query: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302
+ S PK M K+ LC + S L L++ +DG S GLTLRLWDV ++EGEQ L +
Sbjct: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
Query: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362
+FK+ ++ L K S W F R +WA ++++VL++L+ SMK+LT+K DLP P
Sbjct: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223
Query: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391
Q + S+ GK C GD +A P
Sbjct: 224 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 107 bits (267), Expect = 3e-23
Identities = 99/398 (24%), Positives = 167/398 (41%), Gaps = 36/398 (9%)
Query: 74 RKSKWVDMLGDWEKYKSSR--KLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131
R+ KW+DM +W+K+ S R K+ R KG+P ++R W L N +E+ +NPG+++ +
Sbjct: 331 RELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEEL 390
Query: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
E+ + + I++D+ H F R G Q++L IL AY Y P+ GYC+ +
Sbjct: 391 -ERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQA 449
Query: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251
+AA+ L+++P E AFW LVQ+ L G++S +Q + ++ + P
Sbjct: 450 PVAAVLLMHMPAEQAFWCLVQICDK---YLPGYYSAGLEAIQLDGEIFFALLRRASPLAH 506
Query: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKR 311
H ++ + + I + LR+WD++ EG + + + + +
Sbjct: 507 RHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGS 566
Query: 312 LTKTSRCGPWAR----------------FCNRFVDTWARDEDTVLKHLRASMKKLTRKQG 355
+ K C F V E + + A +KK +G
Sbjct: 567 VEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIERENAAQLKKWRETRG 626
Query: 356 DLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQ---APPGPPARFPRPIWSASPPRAP-- 410
+L +P + SR + R + G + PG +R R A P P
Sbjct: 627 EL--QYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPGLKSRGSRAAGGAPSPPPPVR 684
Query: 411 -RSSTPCPGGAV-REDTYPVGTQGVPSPALAQGGPQGS 446
S+ P PG V E +P +PSP P GS
Sbjct: 685 RASAGPAPGPVVTAEGLHP----SLPSPT-GNSTPLGS 717
>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
Length = 508
Score = 105 bits (263), Expect = 8e-23
Identities = 70/239 (29%), Positives = 120/239 (50%), Gaps = 14/239 (5%)
Query: 74 RKSKWVDMLGDWEKY--KSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131
R+SKW+DML +W+K+ K +K+ R KG+P ++RG W L + +NPG++ +
Sbjct: 82 RESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDEL 141
Query: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191
+ + + I+RD+ H F R G Q++L +L AY Y PE GYC+ +
Sbjct: 142 -DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQA 200
Query: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251
IAA+ L+++P E AFW LVQ+ E++ L G++S +Q + ++ P
Sbjct: 201 PIAAVLLMHMPAEQAFWCLVQI--CEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAH 257
Query: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGL----TLRLWDVYLVEGEQALMPITRIAFK 306
H ++ + PL + + S L LR+WD++ EG + + + + K
Sbjct: 258 KHLSRQKI----DPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
Length = 446
Score = 105 bits (261), Expect = 1e-22
Identities = 78/286 (27%), Positives = 126/286 (44%), Gaps = 16/286 (5%)
Query: 32 EDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSS 91
E GP P+R D G + + P + R+ R+ KWV+M WEK S
Sbjct: 27 ELSGPGPYRQ----ADRYGFIGGSSAEPGPGHPPADLIRQ--REMKWVEMTSHWEKTMSR 80
Query: 92 R--KLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDI 149
R K+ + KG+P +R W +L + +PG YQ + E + ++ I RD+
Sbjct: 81 RYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQELAE-APGDPQWMETIGRDL 139
Query: 150 SGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWA 209
H F G Q+ LL +L AY Y PE GYC+ +AA+ L++LP E+AFW
Sbjct: 140 HRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWC 199
Query: 210 LVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCL 269
LVQ+ L G++ P+ V+ + ++ P H + +
Sbjct: 200 LVQIC---EVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWF 256
Query: 270 IRILIDGISLGLTLRLWDVYLVEGEQAL----MPITRIAFKVQQKR 311
+ + + LR+WD +L EG + L + + R+A ++R
Sbjct: 257 LCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAEQR 302
>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
Length = 810
Score = 88.2 bits (217), Expect = 2e-17
Identities = 59/249 (23%), Positives = 115/249 (46%), Gaps = 9/249 (3%)
Query: 78 WVDMLGDWE--KYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
W ++ +WE + K +++ + +KG+P + R +W +L + + M +K+ E
Sbjct: 138 WGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQSMPIKDQ-----YSELL 192
Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195
K +S + I RDI+ T +H FF+++ Q L +++ AY + EVGYC+ + I
Sbjct: 193 KMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVG 252
Query: 196 LFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQD 255
L L+ +PEE+AF V+L+ R L+ P+ + Q E ++ P+ H
Sbjct: 253 LLLMQMPEEEAFCVFVKLMQDYR--LRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQ 310
Query: 256 KKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKT 315
+ + I + L + R++D+++ EG + + + ++ Q L +
Sbjct: 311 SQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQL 370
Query: 316 SRCGPWARF 324
G F
Sbjct: 371 DMEGMLQHF 379
>gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]
Length = 963
Score = 85.5 bits (210), Expect = 1e-16
Identities = 59/254 (23%), Positives = 122/254 (48%), Gaps = 14/254 (5%)
Query: 70 REISRKSKWVDMLGDW--EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKN--- 124
+E+S KW + + S +L + G+P R +W ++ K K+
Sbjct: 629 QEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTE 688
Query: 125 PGRYQIMKEKG-KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPE 183
PG +Q + +K ++ + ++I+ D+ TL + + ++L ++LLA+ NP+
Sbjct: 689 PGHFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPD 748
Query: 184 VGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQ---E 240
+GYC+ L+ + A+ LLYL +EDAFW LV ++ E + +++ T+ G Q Q
Sbjct: 749 IGYCQGLNRLVAVALLYLEQEDAFWCLVTIV--EVFMPRDYYTK---TLLGSQVDQRVFR 803
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
+++ P+ GH ++ + + + +D + + ++WD +L EG + +
Sbjct: 804 DLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRF 863
Query: 301 TRIAFKVQQKRLTK 314
FK +++ + K
Sbjct: 864 ALALFKYKEEEILK 877
>gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]
Length = 914
Score = 85.5 bits (210), Expect = 1e-16
Identities = 59/254 (23%), Positives = 122/254 (48%), Gaps = 14/254 (5%)
Query: 70 REISRKSKWVDMLGDW--EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKN--- 124
+E+S KW + + S +L + G+P R +W ++ K K+
Sbjct: 629 QEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTE 688
Query: 125 PGRYQIMKEKG-KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPE 183
PG +Q + +K ++ + ++I+ D+ TL + + ++L ++LLA+ NP+
Sbjct: 689 PGHFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPD 748
Query: 184 VGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQ---E 240
+GYC+ L+ + A+ LLYL +EDAFW LV ++ E + +++ T+ G Q Q
Sbjct: 749 IGYCQGLNRLVAVALLYLEQEDAFWCLVTIV--EVFMPRDYYTK---TLLGSQVDQRVFR 803
Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
+++ P+ GH ++ + + + +D + + ++WD +L EG + +
Sbjct: 804 DLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRF 863
Query: 301 TRIAFKVQQKRLTK 314
FK +++ + K
Sbjct: 864 ALALFKYKEEEILK 877
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 85.1 bits (209), Expect = 1e-16
Identities = 58/237 (24%), Positives = 111/237 (46%), Gaps = 9/237 (3%)
Query: 78 WVDMLGDWEKYKSSRK--LIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
W + +WE+++ ++ L + KG+P + R +W +L + +M +KN E
Sbjct: 90 WGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQ-----YSELL 144
Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195
K SS + I RDI+ T +H FF+ + Q L +++ AY + EVGYC+ + I
Sbjct: 145 KMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVG 204
Query: 196 LFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQD 255
L L+ +PEE+AF V+L+ + + L+ P+ + Q E+++ P H
Sbjct: 205 LLLMQMPEEEAFCVFVRLM--QEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFR 262
Query: 256 KKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRL 312
+ + + + L + R++D+++ EG + + + +V Q L
Sbjct: 263 SQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAEL 319
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 85.1 bits (209), Expect = 1e-16
Identities = 58/237 (24%), Positives = 111/237 (46%), Gaps = 9/237 (3%)
Query: 78 WVDMLGDWEKYKSSRK--LIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135
W + +WE+++ ++ L + KG+P + R +W +L + +M +KN E
Sbjct: 90 WGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQ-----YSELL 144
Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195
K SS + I RDI+ T +H FF+ + Q L +++ AY + EVGYC+ + I
Sbjct: 145 KMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVG 204
Query: 196 LFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQD 255
L L+ +PEE+AF V+L+ + + L+ P+ + Q E+++ P H
Sbjct: 205 LLLMQMPEEEAFCVFVRLM--QEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFR 262
Query: 256 KKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRL 312
+ + + + L + R++D+++ EG + + + +V Q L
Sbjct: 263 SQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAEL 319
>gi|7661586 TBC1 domain family, member 29 [Homo sapiens]
Length = 150
Score = 83.6 bits (205), Expect = 4e-16
Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 10/137 (7%)
Query: 251 MGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQK 310
MGH DK+ LC Q S L+R+L DGISLGLT LWD+YL+EGEQ LM IT IAFKVQ+
Sbjct: 1 MGHLDKEGLCTQGSSFSWLLRVLNDGISLGLTPCLWDMYLLEGEQMLMLITSIAFKVQRS 60
Query: 311 RLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSAS 370
+T++ W R + R + + L +S++ LT + +G S
Sbjct: 61 LYEETNK-ETWGPATPRALKGTGRAR-PICESLHSSLQALTASES--------SRGPSLL 110
Query: 371 RPVPASRGGKTLCKGDR 387
+ P G + L +GD+
Sbjct: 111 QTPPRVPGQQALSRGDK 127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,944,835
Number of Sequences: 37866
Number of extensions: 1475436
Number of successful extensions: 8114
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 461
Number of HSP's that attempted gapping in prelim test: 6723
Number of HSP's gapped (non-prelim): 1558
length of query: 549
length of database: 18,247,518
effective HSP length: 107
effective length of query: 442
effective length of database: 14,195,856
effective search space: 6274568352
effective search space used: 6274568352
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.