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Search of human proteins with 157384986
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
sapiens]
(769 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ... 1575 0.0
gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ... 1570 0.0
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ... 1547 0.0
gi|34915994 transducin-like enhancer protein 4 [Homo sapiens] 1291 0.0
gi|21541824 transducin-like enhancer protein 1 [Homo sapiens] 1246 0.0
gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo s... 974 0.0
gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo ... 843 0.0
gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo ... 783 0.0
gi|5706731 amino-terminal enhancer of split isoform b [Homo sapi... 231 1e-60
gi|39812027 amino-terminal enhancer of split isoform c [Homo sap... 229 7e-60
gi|39812019 amino-terminal enhancer of split isoform a [Homo sap... 226 5e-59
gi|221136834 transducin-like enhancer of split 6 isoform 1 [Homo... 199 1e-50
gi|13376099 transducin-like enhancer of split 6 isoform 2 [Homo ... 199 1e-50
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 89 2e-17
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 89 2e-17
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 89 2e-17
gi|26665869 WD repeat domain 51B [Homo sapiens] 87 8e-17
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 84 5e-16
gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is... 75 2e-13
gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i... 75 2e-13
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 74 5e-13
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 74 7e-13
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 70 7e-12
gi|5174447 guanine nucleotide binding protein (G protein), beta ... 69 2e-11
gi|16554629 WD repeat domain 5 [Homo sapiens] 69 2e-11
gi|16554627 WD repeat domain 5 [Homo sapiens] 69 2e-11
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 69 2e-11
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 69 2e-11
gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [H... 68 4e-11
gi|21071067 TBP-associated factor 5 [Homo sapiens] 68 4e-11
>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
sapiens]
Length = 769
Score = 1575 bits (4078), Expect = 0.0
Identities = 769/769 (100%), Positives = 769/769 (100%)
Query: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH
Sbjct: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
Query: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN
Sbjct: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
Query: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTV 180
AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTV
Sbjct: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTV 180
Query: 181 KDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDS 240
KDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDS
Sbjct: 181 KDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDS 240
Query: 241 DGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSK 300
DGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSK
Sbjct: 241 DGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSK 300
Query: 301 TKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTPISI 360
TKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTPISI
Sbjct: 301 TKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTPISI 360
Query: 361 TSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGF 420
TSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGF
Sbjct: 361 TSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGF 420
Query: 421 DPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTL 480
DPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTL
Sbjct: 421 DPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTL 480
Query: 481 SHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD 540
SHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD
Sbjct: 481 SHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD 540
Query: 541 GRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVW 600
GRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVW
Sbjct: 541 GRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVW 600
Query: 601 DLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIF 660
DLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIF
Sbjct: 601 DLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIF 660
Query: 661 SLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNL 720
SLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNL
Sbjct: 661 SLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNL 720
Query: 721 LNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 769
LNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY
Sbjct: 721 LNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 769
>gi|157384982 transducin-like enhancer protein 3 isoform a [Homo
sapiens]
Length = 772
Score = 1570 bits (4064), Expect = 0.0
Identities = 769/772 (99%), Positives = 769/772 (99%), Gaps = 3/772 (0%)
Query: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH
Sbjct: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
Query: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN
Sbjct: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
Query: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTV 180
AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTV
Sbjct: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTV 180
Query: 181 KDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDS 240
KDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDS
Sbjct: 181 KDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDS 240
Query: 241 DGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSK 300
DGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSK
Sbjct: 241 DGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSK 300
Query: 301 TKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPI---ASALRTP 357
TKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPI ASALRTP
Sbjct: 301 TKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIGIMASALRTP 360
Query: 358 ISITSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGA 417
ISITSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGA
Sbjct: 361 ISITSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGA 420
Query: 418 VGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQI 477
VGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQI
Sbjct: 421 VGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQI 480
Query: 478 NTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKL 537
NTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKL
Sbjct: 481 NTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKL 540
Query: 538 LPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNI 597
LPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNI
Sbjct: 541 LPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNI 600
Query: 598 AVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTS 657
AVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTS
Sbjct: 601 AVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTS 660
Query: 658 QIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGK 717
QIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGK
Sbjct: 661 QIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGK 720
Query: 718 DNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 769
DNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY
Sbjct: 721 DNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 772
>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
sapiens]
Length = 760
Score = 1547 bits (4005), Expect = 0.0
Identities = 760/769 (98%), Positives = 760/769 (98%), Gaps = 9/769 (1%)
Query: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH
Sbjct: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
Query: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN
Sbjct: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
Query: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTV 180
AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTV
Sbjct: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTV 180
Query: 181 KDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDS 240
KDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDS
Sbjct: 181 KDEKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDS 240
Query: 241 DGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSK 300
DGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSK
Sbjct: 241 DGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSK 300
Query: 301 TKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTPISI 360
TKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMP ASALRTPISI
Sbjct: 301 TKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMP---------ASALRTPISI 351
Query: 361 TSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGF 420
TSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGF
Sbjct: 352 TSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGF 411
Query: 421 DPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTL 480
DPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTL
Sbjct: 412 DPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTL 471
Query: 481 SHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD 540
SHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD
Sbjct: 472 SHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD 531
Query: 541 GRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVW 600
GRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVW
Sbjct: 532 GRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVW 591
Query: 601 DLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIF 660
DLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIF
Sbjct: 592 DLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIF 651
Query: 661 SLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNL 720
SLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNL
Sbjct: 652 SLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNL 711
Query: 721 LNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 769
LNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY
Sbjct: 712 LNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 760
>gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]
Length = 773
Score = 1291 bits (3342), Expect = 0.0
Identities = 640/775 (82%), Positives = 696/775 (89%), Gaps = 15/775 (1%)
Query: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
MYPQ RHPAPHQP QP FKFT++ESCDRIK+EFQFLQAQYHSLK+E +KLA+EKTEMQRH
Sbjct: 8 MYPQTRHPAPHQPAQP-FKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH 66
Query: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
YVMYYEMSYGLNIEMHKQ EI KRLN I AQ++PFLSQEHQQQV QAVERAKQVTM ELN
Sbjct: 67 YVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELN 126
Query: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALG-ALGSQAHLT 179
AIIGQQ LQAQHLSH HG PV L PHPSGLQPP IPP+ GSS+GLLAL ALG Q+HL
Sbjct: 127 AIIGQQ-LQAQHLSHG-HGLPVPLTPHPSGLQPPAIPPI-GSSAGLLALSSALGGQSHLP 183
Query: 180 VKDEKNHHELDH-RERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRY 238
+KDEK HH+ DH R+R+S ++SVSPS S R +EKHR SADYS E+KK+K EEK+ +RY
Sbjct: 184 IKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARY 243
Query: 239 DSDGDKSDD-LVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTP 297
DSDG+KSDD LVVDVSNEDP++PR SPAHSP ENGLDK R LKKDAP SPAS+ASSSSTP
Sbjct: 244 DSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSSSTP 303
Query: 298 SSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPIASALRTP 357
SSK+K+L N+KS+TP KSNTPTPR DAPTPG+++TPGLR +PGKPPG+DP+AS+LRTP
Sbjct: 304 SSKSKELSLNEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLASSLRTP 363
Query: 358 ISITSSYAAPFAMMSHHEMNGSLTSPGA-YAGLHNIPPQMSAAAAAAAAA--YGRSPMVS 414
+++ Y PF ++ H MNG LTSPGA YAGLHNI PQMSAAAAAAAAA YGRSP+V
Sbjct: 364 MAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSPVV- 422
Query: 415 FGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHA 474
GFDPH MR +P +L IPGGKPAYSFHVSADGQMQPVPFP DAL GPGIPRHA
Sbjct: 423 ----GFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHA 478
Query: 475 RQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRS 534
RQINTL+HGEVVCAVTISNPTRHVYTGGKGCVK+WDIS PG+KSP+SQLDCLNRDNYIRS
Sbjct: 479 RQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRS 538
Query: 535 CKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSD 594
C+LLPDGRTLIVGGEASTL+IWDLA+PTPRIKAELTSSAPACYALAISPD+KVCFSCCSD
Sbjct: 539 CRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSD 598
Query: 595 GNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHD 654
GNIAVWDLHNQTLVRQFQGHTDGASCIDIS+DGTKLWTGGLDNTVRSWDLREGRQLQQHD
Sbjct: 599 GNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHD 658
Query: 655 FTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVS 714
FTSQIFSLGYCPTGEWLAVGME+SNVEVLH TKPDKYQLHLHESCVLSLKFA+CGKWFVS
Sbjct: 659 FTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVS 718
Query: 715 TGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 769
TGKDNLLNAWRTPYGASIFQSKESSSVLSCDIS DDKYIVTGSGDKKATVYEVIY
Sbjct: 719 TGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 773
>gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]
Length = 770
Score = 1246 bits (3225), Expect = 0.0
Identities = 621/778 (79%), Positives = 680/778 (87%), Gaps = 17/778 (2%)
Query: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
M+PQ RHP PHQ FKFT+ ES DRIK+EFQFLQAQYHSLK+E +KLA+EKTEMQRH
Sbjct: 1 MFPQSRHPTPHQAAGQPFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH 60
Query: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
YVMYYEMSYGLNIEMHKQTEIAKRLNTI AQ++PFLSQEHQQQVAQAVERAKQVTM ELN
Sbjct: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELN 120
Query: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALG-ALGSQAHLT 179
AIIGQQQLQAQHLSH HGPPV L PHPSGLQPPGIPP+ G S+GLLAL AL Q+HL
Sbjct: 121 AIIGQQQLQAQHLSHG-HGPPVPLTPHPSGLQPPGIPPL-GGSAGLLALSSALSGQSHLA 178
Query: 180 VKDEKNHHELDH-RERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRY 238
+KD+K HH+ +H R+RE +NS+ +SLR ++K R ++S + KKRK ++KDS S Y
Sbjct: 179 IKDDKKHHDAEHHRDREPGTSNSLLVPDSLRGTDKRRNGPEFSNDIKKRKVDDKDS-SHY 237
Query: 239 DSDGDKSDD-LVVDVSNEDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTP 297
DSDGDKSDD LVVDVSNEDP++PR SPAHSP ENG+DK R LKKDA +SPAS ASS+S+
Sbjct: 238 DSDGDKSDDNLVVDVSNEDPSSPRASPAHSPRENGIDKNRLLKKDASSSPASTASSASST 297
Query: 298 SSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPI----ASA 353
S K+K++ ++K+STP LKS+TPTPR+D PTPGTS TPGLR GKPP +DP+ A+
Sbjct: 298 SLKSKEMSLHEKASTPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKPPAIDPLVNQAAAG 357
Query: 354 LRTPISITSSYAAPFAMMSHHEMNGSLTSPGA-YAGLHNIPPQMSAAAAAAAA-AYGRSP 411
LRTP+++ Y APF M+ H MNG LTSPGA YA LHN+ PQMSAAAAAAA AYGRSP
Sbjct: 358 LRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAAYASLHNMSPQMSAAAAAAAVVAYGRSP 417
Query: 412 MVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIP 471
MV GFDP P MR +P +LA IPGGKPAYSFHV+ADGQMQPVPFP DAL GPGIP
Sbjct: 418 MV-----GFDPPPHMRVPTIPPNLAGIPGGKPAYSFHVTADGQMQPVPFPPDALIGPGIP 472
Query: 472 RHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNY 531
RHARQINTL+HGEVVCAVTISNPTRHVYTGGKGCVK+WDIS PG+KSP+SQLDCLNRDNY
Sbjct: 473 RHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNY 532
Query: 532 IRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSC 591
IRSCKLLPDG TLIVGGEASTL+IWDLA+PTPRIKAELTSSAPACYALAISPD+KVCFSC
Sbjct: 533 IRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSC 592
Query: 592 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQ 651
CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDIS+DGTKLWTGGLDNTVRSWDLREGRQLQ
Sbjct: 593 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQ 652
Query: 652 QHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKW 711
QHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLH KPDKYQLHLHESCVLSLKFAYCGKW
Sbjct: 653 QHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKW 712
Query: 712 FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 769
FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDIS DDKYIVTGSGDKKATVYEVIY
Sbjct: 713 FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY 770
>gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo
sapiens]
Length = 743
Score = 974 bits (2518), Expect = 0.0
Identities = 512/778 (65%), Positives = 601/778 (77%), Gaps = 44/778 (5%)
Query: 1 MYPQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRH 60
MYPQGRHP P Q GQP FKF++ E CDRIK+EFQFLQAQYHSLK+E +KLA+EKTEMQRH
Sbjct: 1 MYPQGRHPTPLQSGQP-FKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH 59
Query: 61 YVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELN 120
YVMYYEMSYGLNIEMHKQ EI KRL+ I AQI+PFL+QEHQQQV QAVERAKQVT+ ELN
Sbjct: 60 YVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELN 119
Query: 121 AIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLAL-GALGSQAHLT 179
++IGQQ Q LSH H PPV L P P+GL V GS++GLLAL GAL +QA L
Sbjct: 120 SLIGQQ---LQPLSH--HAPPVPLTPRPAGL-------VGGSATGLLALSGALAAQAQLA 167
Query: 180 --VKDEKNHHELDHR--ERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSL 235
VK+++ E + ER S + S SP ESL E+ G K++A+EK+
Sbjct: 168 AAVKEDRAGVEAEGSRVERAPSRSASPSPPESLVEEERPSGPGG----GGKQRADEKEPS 223
Query: 236 SRYDSDGDKSD-DLVVDVSN-EDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASS 293
Y+SD DKSD +LVVD +P +P +P P ++D SPAS+ASS
Sbjct: 224 GPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKVPI-----CIPARRDLVDSPASLASS 278
Query: 294 SSTPSSKTKDLGHND-KSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKP-PGMDPIA 351
+P + K+L ND +STP KS +P DA TPG S+ L + KP P D +A
Sbjct: 279 LGSPLPRAKELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVA 338
Query: 352 SALRTPISITSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSP 411
LR+P++++S + F++ SH +NG L+ P +Y LH + PQ+S++ YGRSP
Sbjct: 339 --LRSPLTLSSPFTTSFSLGSHSTLNGDLSVPSSYVSLH-LSPQVSSSVV-----YGRSP 390
Query: 412 MVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIP 471
+++F + HP +R + + SSL SIPGGKPAYSFHVSADGQMQPVPFP DAL G GIP
Sbjct: 391 VMAF-----ESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIP 445
Query: 472 RHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNY 531
RHARQ++TL+HGEVVCAVTIS T+HVYTGGKGCVK+WD+ QPG+K+P++QLDCLNRDNY
Sbjct: 446 RHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNY 505
Query: 532 IRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSC 591
IRSCKLLPDGR+LIVGGEASTL+IWDLA+PTPRIKAELTSSAPACYALA+SPDAKVCFSC
Sbjct: 506 IRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSC 565
Query: 592 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQ 651
CSDGNI VWDL NQT+VRQFQGHTDGASCIDIS GT+LWTGGLDNTVR WDLREGRQLQ
Sbjct: 566 CSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQ 625
Query: 652 QHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKW 711
QHDF+SQIFSLG+CP +WLAVGMESSNVE+LH KP+KYQLHLHESCVLSLKFA CG+W
Sbjct: 626 QHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRW 685
Query: 712 FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 769
FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDIS ++KYIVTGSGDKKATVYEV+Y
Sbjct: 686 FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY 743
>gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo
sapiens]
Length = 706
Score = 843 bits (2179), Expect = 0.0
Identities = 450/708 (63%), Positives = 535/708 (75%), Gaps = 43/708 (6%)
Query: 10 PHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYVMYYEMSY 69
P Q GQP FKF++ E CDRIK+EFQFLQAQYHSLK+E +KLA+EKTEMQRHYVMYYEMSY
Sbjct: 23 PLQSGQP-FKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSY 81
Query: 70 GLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQQQLQ 129
GLNIEMHKQ EI KRL+ I AQI+PFL+QEHQQQV QAVERAKQVT+ ELN++IGQQQLQ
Sbjct: 82 GLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQQLQ 141
Query: 130 AQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLAL-GALGSQAHLT--VKDEKNH 186
LSH H PPV L P P+GL V GS++GLLAL GAL +QA L VK+++
Sbjct: 142 P--LSH--HAPPVPLTPRPAGL-------VGGSATGLLALSGALAAQAQLAAAVKEDRAG 190
Query: 187 HELDHR--ERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDGDK 244
E + ER S + S SP ESL E+ G K++A+EK+ Y+SD DK
Sbjct: 191 VEAEGSRVERAPSRSASPSPPESLVEEERPSGPGG----GGKQRADEKEPSGPYESDEDK 246
Query: 245 SD-DLVVDVSN-EDPATPRVSPAHSPPENGLDKARSLKKDAPTSPASVASSSSTPSSKTK 302
SD +LVVD +P +P +P P ++D SPAS+ASS +P + K
Sbjct: 247 SDYNLVVDEDQPSEPPSPATTPCGKVPI-----CIPARRDLVDSPASLASSLGSPLPRAK 301
Query: 303 DLGHND-KSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKP-PGMDPIASALRTPISI 360
+L ND +STP KS +P DA TPG S+ L + KP P D +A LR+P+++
Sbjct: 302 ELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVA--LRSPLTL 359
Query: 361 TSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSPMVSFGAVGF 420
+S + F++ SH +NG L+ P +Y LH + PQ+S++ YGRSP+++F
Sbjct: 360 SSPFTTSFSLGSHSTLNGDLSVPSSYVSLH-LSPQVSSSVV-----YGRSPVMAF----- 408
Query: 421 DPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIPRHARQINTL 480
+ HP +R + + SSL SIPGGKPAYSFHVSADGQMQPVPFP DAL G GIPRHARQ++TL
Sbjct: 409 ESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTL 468
Query: 481 SHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD 540
+HGEVVCAVTIS T+HVYTGGKGCVK+WD+ QPG+K+P++QLDCLNRDNYIRSCKLLPD
Sbjct: 469 AHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPD 528
Query: 541 GRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVW 600
GR+LIVGGEASTL+IWDLA+PTPRIKAELTSSAPACYALA+SPDAKVCFSCCSDGNI VW
Sbjct: 529 GRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVW 588
Query: 601 DLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIF 660
DL NQT+VRQFQGHTDGASCIDIS GT+LWTGGLDNTVR WDLREGRQLQQHDF+SQIF
Sbjct: 589 DLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIF 648
Query: 661 SLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYC 708
SLG+CP +WLAVGMESSNVE+LH KP+KYQLHLHESCVLSLKFA C
Sbjct: 649 SLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASC 696
Score = 30.0 bits (66), Expect = 8.5
Identities = 29/148 (19%), Positives = 53/148 (35%), Gaps = 8/148 (5%)
Query: 626 DGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQI---FSLGYCPTGEWLAVGMESSNV-- 680
DG L GG +T+ WDL + + TS ++L P + N+
Sbjct: 528 DGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVV 587
Query: 681 -EVLHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESS 739
++ + T ++Q H + + + W + G DN + W G + Q SS
Sbjct: 588 WDLQNQTMVRQFQGHTDGASCIDISDYGTRLW--TGGLDNTVRCWDLREGRQLQQHDFSS 645
Query: 740 SVLSCDISADDKYIVTGSGDKKATVYEV 767
+ S + ++ G + V
Sbjct: 646 QIFSLGHCPNQDWLAVGMESSNVEILHV 673
>gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo
sapiens]
Length = 621
Score = 783 bits (2023), Expect = 0.0
Identities = 426/718 (59%), Positives = 497/718 (69%), Gaps = 102/718 (14%)
Query: 57 MQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTM 116
MQRHYVMYYEMSYGLNIEMHKQ EI KRL+ I AQI+PFL+QEHQQQV QAVERAKQVT+
Sbjct: 1 MQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTV 60
Query: 117 TELNAIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQA 176
ELN++IG A+ PP L P G G +
Sbjct: 61 GELNSLIGS----------ASPSPPESLVEEERPSGPGG-----------------GGKQ 93
Query: 177 HLTVKDEKNHHELDHRERESSANNSV---SPSESLRASEKHRGSADYSMEAKKRKAEEKD 233
K+ +E D E +S N V PSE + G + A++
Sbjct: 94 RADEKEPSGPYESD--EDKSDYNLVVDEDQPSEPPSPATTPCGKVPICIPARR------- 144
Query: 234 SLSRYDSDGDKSDDLVVDVSNEDPATPRVSPAHSPPENGLDKARSL-KKDAPTSPASVAS 292
DLV D S SP L +A+ L D P
Sbjct: 145 -------------DLV------DSPASLASSLGSP----LPRAKELILNDLP-------- 173
Query: 293 SSSTPSSKTKDLGHNDKSSTPGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKP-PGMDPIA 351
+STP+SK+ D +P DA TPG S+ L + KP P D +
Sbjct: 174 -ASTPASKSCD----------------SSPPQDASTPGPSSASHLCQLAAKPAPSTDSV- 215
Query: 352 SALRTPISITSSYAAPFAMMSHHEMNGSLTSPGAYAGLHNIPPQMSAAAAAAAAAYGRSP 411
ALR+P++++S + F++ SH +NG L+ P +Y LH + PQ+S ++ YGRSP
Sbjct: 216 -ALRSPLTLSSPFTTSFSLGSHSTLNGDLSVPSSYVSLH-LSPQVS-----SSVVYGRSP 268
Query: 412 MVSFGAVGFDPHPPMRATGLPSSLASIPGGKPAYSFHVSADGQMQPVPFPHDALAGPGIP 471
+++ F+ HP +R + + SSL SIPGGKPAYSFHVSADGQMQPVPFP DAL G GIP
Sbjct: 269 VMA-----FESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIP 323
Query: 472 RHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNY 531
RHARQ++TL+HGEVVCAVTIS T+HVYTGGKGCVK+WD+ QPG+K+P++QLDCLNRDNY
Sbjct: 324 RHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNY 383
Query: 532 IRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSC 591
IRSCKLLPDGR+LIVGGEASTL+IWDLA+PTPRIKAELTSSAPACYALA+SPDAKVCFSC
Sbjct: 384 IRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSC 443
Query: 592 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQ 651
CSDGNI VWDL NQT+VRQFQGHTDGASCIDIS GT+LWTGGLDNTVR WDLREGRQLQ
Sbjct: 444 CSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQ 503
Query: 652 QHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLSLKFAYCGKW 711
QHDF+SQIFSLG+CP +WLAVGMESSNVE+LH KP+KYQLHLHESCVLSLKFA CG+W
Sbjct: 504 QHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRW 563
Query: 712 FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY 769
FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDIS ++KYIVTGSGDKKATVYEV+Y
Sbjct: 564 FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY 621
>gi|5706731 amino-terminal enhancer of split isoform b [Homo
sapiens]
Length = 197
Score = 231 bits (590), Expect = 1e-60
Identities = 125/201 (62%), Positives = 151/201 (75%), Gaps = 6/201 (2%)
Query: 1 MYPQGRHP-APHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQR 59
M+PQ RH + H P Q KFT ++SCDRIKDEFQ LQAQYHSLK+E DKLA+EK+EMQR
Sbjct: 2 MFPQSRHSGSSHLPQQ--LKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQR 59
Query: 60 HYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTEL 119
HYVMYYEMSYGLNIEMHKQ EI KRLN I AQ++P+LSQEHQQQV A+ERAKQVT EL
Sbjct: 60 HYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPEL 119
Query: 120 NAIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLT 179
N+II +QQLQA LS + L P P GLQPP +P V+ + +GLL+L ALGSQAHL+
Sbjct: 120 NSII-RQQLQAHQLSQ-LQALALPLTPLPVGLQPPSLPAVS-AGTGLLSLSALGSQAHLS 176
Query: 180 VKDEKNHHELDHRERESSANN 200
+D+ H H+E + ++
Sbjct: 177 KEDKNGHDGDTHQEDDGEKSD 197
>gi|39812027 amino-terminal enhancer of split isoform c [Homo
sapiens]
Length = 196
Score = 229 bits (584), Expect = 7e-60
Identities = 124/201 (61%), Positives = 150/201 (74%), Gaps = 7/201 (3%)
Query: 1 MYPQGRHP-APHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQR 59
M+PQ RH + H P Q KFT ++SCDRIKDEFQ LQAQYHSLK+E DKLA+EK+EMQR
Sbjct: 2 MFPQSRHSGSSHLPQQ--LKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQR 59
Query: 60 HYVMYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTEL 119
HYVMYYEMSYGLNIEMHKQ EI KRLN I AQ++P+LSQEHQQQV A+ERAKQVT EL
Sbjct: 60 HYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPEL 119
Query: 120 NAIIGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLT 179
N+II +QLQA LS + L P P GLQPP +P V+ + +GLL+L ALGSQAHL+
Sbjct: 120 NSII--RQLQAHQLSQ-LQALALPLTPLPVGLQPPSLPAVS-AGTGLLSLSALGSQAHLS 175
Query: 180 VKDEKNHHELDHRERESSANN 200
+D+ H H+E + ++
Sbjct: 176 KEDKNGHDGDTHQEDDGEKSD 196
>gi|39812019 amino-terminal enhancer of split isoform a [Homo
sapiens]
Length = 264
Score = 226 bits (577), Expect = 5e-59
Identities = 122/198 (61%), Positives = 147/198 (74%), Gaps = 5/198 (2%)
Query: 3 PQGRHPAPHQPGQPGFKFTVAESCDRIKDEFQFLQAQYHSLKVEYDKLANEKTEMQRHYV 62
P G + H P Q KFT ++SCDRIKDEFQ LQAQYHSLK+E DKLA+EK+EMQRHYV
Sbjct: 72 PAGCRGSSHLPQQ--LKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYV 129
Query: 63 MYYEMSYGLNIEMHKQTEIAKRLNTILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAI 122
MYYEMSYGLNIEMHKQ EI KRLN I AQ++P+LSQEHQQQV A+ERAKQVT ELN+I
Sbjct: 130 MYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSI 189
Query: 123 IGQQQLQAQHLSHATHGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQAHLTVKD 182
I +QQLQA LS + L P P GLQPP +P V+ + +GLL+L ALGSQAHL+ +D
Sbjct: 190 I-RQQLQAHQLSQ-LQALALPLTPLPVGLQPPSLPAVS-AGTGLLSLSALGSQAHLSKED 246
Query: 183 EKNHHELDHRERESSANN 200
+ H H+E + ++
Sbjct: 247 KNGHDGDTHQEDDGEKSD 264
>gi|221136834 transducin-like enhancer of split 6 isoform 1 [Homo
sapiens]
Length = 572
Score = 199 bits (505), Expect = 1e-50
Identities = 104/314 (33%), Positives = 181/314 (57%), Gaps = 10/314 (3%)
Query: 463 DALAGPG----IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKS 518
DAL G +P ++ L+HGE+V A IS+ TRHV+T G+ +K+W ++ ++
Sbjct: 262 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 321
Query: 519 --PISQLDCLNRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPA 575
P S L ++R+C L + R+L+ GG +++++WDLA+P+ +K +L +
Sbjct: 322 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 381
Query: 576 CYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGL 635
C AL + DA + F+ + G + +WDL +Q++VR +G+ DG I + G +WTGG
Sbjct: 382 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGP 439
Query: 636 DNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL 695
D +R WD R + ++ F SQI SL + P +W+ +GM + + + ++ +
Sbjct: 440 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 499
Query: 696 HESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVT 755
+S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S++++ +VT
Sbjct: 500 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 559
Query: 756 GSGDKKATVYEVIY 769
GSG+ A+VY++ Y
Sbjct: 560 GSGE-HASVYQITY 572
>gi|13376099 transducin-like enhancer of split 6 isoform 2 [Homo
sapiens]
Length = 449
Score = 199 bits (505), Expect = 1e-50
Identities = 104/314 (33%), Positives = 181/314 (57%), Gaps = 10/314 (3%)
Query: 463 DALAGPG----IPRHARQINTLSHGEVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKS 518
DAL G +P ++ L+HGE+V A IS+ TRHV+T G+ +K+W ++ ++
Sbjct: 139 DALPGQSKRLAVPCKLEKMRILAHGELVLATAISSFTRHVFTCGRRGIKVWSLTGQVAED 198
Query: 519 --PISQLDCLNRDNYIRSCKLLPDGRTLIVGG-EASTLTIWDLASPTPRIKAELTSSAPA 575
P S L ++R+C L + R+L+ GG +++++WDLA+P+ +K +L +
Sbjct: 199 RFPESHLPIQTPGAFLRTCLLSSNSRSLLTGGYNLASVSVWDLAAPSLHVKEQLPCAGLN 258
Query: 576 CYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGL 635
C AL + DA + F+ + G + +WDL +Q++VR +G+ DG I + G +WTGG
Sbjct: 259 CQALDANLDANLAFASFTSGVVRIWDLRDQSVVRDLKGYPDGVKSIVVK--GYNIWTGGP 316
Query: 636 DNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL 695
D +R WD R + ++ F SQI SL + P +W+ +GM + + + ++ +
Sbjct: 317 DACLRCWDQRTIMKPLEYQFKSQIMSLSHSPQEDWVLLGMANGQQWLQSTSGSQRHMVGQ 376
Query: 696 HESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVT 755
+S +LS+KF+ G+W+ S G D+ L + P G +F+ E S V CD+S++++ +VT
Sbjct: 377 KDSVILSVKFSPFGQWWASVGMDDFLGVYSMPAGTKVFEVPEMSPVTCCDVSSNNRLVVT 436
Query: 756 GSGDKKATVYEVIY 769
GSG+ A+VY++ Y
Sbjct: 437 GSGE-HASVYQITY 449
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 89.0 bits (219), Expect = 2e-17
Identities = 60/259 (23%), Positives = 111/259 (42%), Gaps = 12/259 (4%)
Query: 474 ARQINTLSHGEVVCAVTISNPTRHVYTGGKG--CVKIWDISQPGSKSPISQLDCLNRDNY 531
+R H + V V S P+ H+ G V+IW + G +
Sbjct: 14 SRAYRFTGHKDAVTCVNFS-PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTAT----- 67
Query: 532 IRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSC 591
+RS DG++ + + T+ +W A+ + L+ SPD ++ S
Sbjct: 68 VRSVHFCSDGQSFVTASDDKTVKVW--ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSA 125
Query: 592 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQ 651
D + +WD ++ V + H + +D GT + G+DNTV+ WD+R R LQ
Sbjct: 126 SDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ 185
Query: 652 QHDF-TSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPD-KYQLHLHESCVLSLKFAYCG 709
+ ++ + L + P+G +L S +++L + Y LH H+ ++ F+ G
Sbjct: 186 HYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTG 245
Query: 710 KWFVSTGKDNLLNAWRTPY 728
++F S G D + W++ +
Sbjct: 246 EYFASGGSDEQVMVWKSNF 264
Score = 58.5 bits (140), Expect = 2e-08
Identities = 36/133 (27%), Positives = 58/133 (43%), Gaps = 2/133 (1%)
Query: 594 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLR-EGRQLQQ 652
D + VW + Q+ +F GH D +C++ S G L +G D TVR W +G
Sbjct: 2 DSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVF 61
Query: 653 HDFTSQIFSLGYCPTGEWLAVGMESSNVEV-LHHTKPDKYQLHLHESCVLSLKFAYCGKW 711
T+ + S+ +C G+ + V+V H + + L H + V KF+ G+
Sbjct: 62 RAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRL 121
Query: 712 FVSTGKDNLLNAW 724
VS D + W
Sbjct: 122 IVSASDDKTVKLW 134
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 89.0 bits (219), Expect = 2e-17
Identities = 60/259 (23%), Positives = 111/259 (42%), Gaps = 12/259 (4%)
Query: 474 ARQINTLSHGEVVCAVTISNPTRHVYTGGKG--CVKIWDISQPGSKSPISQLDCLNRDNY 531
+R H + V V S P+ H+ G V+IW + G +
Sbjct: 52 SRAYRFTGHKDAVTCVNFS-PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTAT----- 105
Query: 532 IRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSC 591
+RS DG++ + + T+ +W A+ + L+ SPD ++ S
Sbjct: 106 VRSVHFCSDGQSFVTASDDKTVKVW--ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSA 163
Query: 592 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQ 651
D + +WD ++ V + H + +D GT + G+DNTV+ WD+R R LQ
Sbjct: 164 SDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ 223
Query: 652 QHDF-TSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPD-KYQLHLHESCVLSLKFAYCG 709
+ ++ + L + P+G +L S +++L + Y LH H+ ++ F+ G
Sbjct: 224 HYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTG 283
Query: 710 KWFVSTGKDNLLNAWRTPY 728
++F S G D + W++ +
Sbjct: 284 EYFASGGSDEQVMVWKSNF 302
Score = 67.0 bits (162), Expect = 6e-11
Identities = 42/166 (25%), Positives = 78/166 (46%), Gaps = 7/166 (4%)
Query: 606 TLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQ---IFSL 662
+L R F+GH D +C+D S + +L +G +D+ + W ++ Q + + FT + +
Sbjct: 10 SLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKP--QSRAYRFTGHKDAVTCV 67
Query: 663 GYCPTGEWLAVGMESSNVEV-LHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLL 721
+ P+G LA G V + + + K + H + V S+ F G+ FV+ D +
Sbjct: 68 NFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTV 127
Query: 722 NAWRTPYGASIFQSKESSSVLSC-DISADDKYIVTGSGDKKATVYE 766
W T +F + + + C S D + IV+ S DK +++
Sbjct: 128 KVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Score = 60.5 bits (145), Expect = 6e-09
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 2/164 (1%)
Query: 563 PRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 622
P ++ A + S + K S D + VW + Q+ +F GH D +C++
Sbjct: 9 PSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVN 68
Query: 623 ISHDGTKLWTGGLDNTVRSWDLR-EGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVE 681
S G L +G D TVR W +G T+ + S+ +C G+ + V+
Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVK 128
Query: 682 V-LHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW 724
V H + + L H + V KF+ G+ VS D + W
Sbjct: 129 VWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 89.0 bits (219), Expect = 2e-17
Identities = 60/259 (23%), Positives = 111/259 (42%), Gaps = 12/259 (4%)
Query: 474 ARQINTLSHGEVVCAVTISNPTRHVYTGGKG--CVKIWDISQPGSKSPISQLDCLNRDNY 531
+R H + V V S P+ H+ G V+IW + G +
Sbjct: 52 SRAYRFTGHKDAVTCVNFS-PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTAT----- 105
Query: 532 IRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSC 591
+RS DG++ + + T+ +W A+ + L+ SPD ++ S
Sbjct: 106 VRSVHFCSDGQSFVTASDDKTVKVW--ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSA 163
Query: 592 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQ 651
D + +WD ++ V + H + +D GT + G+DNTV+ WD+R R LQ
Sbjct: 164 SDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ 223
Query: 652 QHDF-TSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPD-KYQLHLHESCVLSLKFAYCG 709
+ ++ + L + P+G +L S +++L + Y LH H+ ++ F+ G
Sbjct: 224 HYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTG 283
Query: 710 KWFVSTGKDNLLNAWRTPY 728
++F S G D + W++ +
Sbjct: 284 EYFASGGSDEQVMVWKSNF 302
Score = 67.0 bits (162), Expect = 6e-11
Identities = 42/166 (25%), Positives = 78/166 (46%), Gaps = 7/166 (4%)
Query: 606 TLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQ---IFSL 662
+L R F+GH D +C+D S + +L +G +D+ + W ++ Q + + FT + +
Sbjct: 10 SLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKP--QSRAYRFTGHKDAVTCV 67
Query: 663 GYCPTGEWLAVGMESSNVEV-LHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLL 721
+ P+G LA G V + + + K + H + V S+ F G+ FV+ D +
Sbjct: 68 NFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTV 127
Query: 722 NAWRTPYGASIFQSKESSSVLSC-DISADDKYIVTGSGDKKATVYE 766
W T +F + + + C S D + IV+ S DK +++
Sbjct: 128 KVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Score = 60.5 bits (145), Expect = 6e-09
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 2/164 (1%)
Query: 563 PRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 622
P ++ A + S + K S D + VW + Q+ +F GH D +C++
Sbjct: 9 PSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVN 68
Query: 623 ISHDGTKLWTGGLDNTVRSWDLR-EGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVE 681
S G L +G D TVR W +G T+ + S+ +C G+ + V+
Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVK 128
Query: 682 V-LHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW 724
V H + + L H + V KF+ G+ VS D + W
Sbjct: 129 VWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 86.7 bits (213), Expect = 8e-17
Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 10/259 (3%)
Query: 473 HARQINTLSHGEVVCAVTISNPTRHVYTGGKG-CVKIWDISQPGSKSPISQLDCLNRDNY 531
HAR + H +VV +V S + + + V++W P + S+
Sbjct: 50 HARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWI---PDKRGKFSEFKAHTAP-- 104
Query: 532 IRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSC 591
+RS DG+ L E ++ +W + R L SPD ++ SC
Sbjct: 105 VRSVDFSADGQFLATASEDKSIKVWSMYRQ--RFLYSLYRHTHWVRCAKFSPDGRLIVSC 162
Query: 592 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQ 651
D I +WD N+ V F A+ +D + GT + + G D TV+ WD+R + LQ
Sbjct: 163 SEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQ 222
Query: 652 QHDFTS-QIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDK-YQLHLHESCVLSLKFAYCG 709
+ S + + + P+G +L +++L + Y L H V ++ F+ G
Sbjct: 223 HYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGG 282
Query: 710 KWFVSTGKDNLLNAWRTPY 728
+ F S G D + WRT +
Sbjct: 283 ELFASGGADTQVLLWRTNF 301
Score = 59.7 bits (143), Expect = 1e-08
Identities = 46/212 (21%), Positives = 88/212 (41%), Gaps = 3/212 (1%)
Query: 559 ASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGA 618
A+ P ++ A +L +SP+ K + D + +W+ ++ GH D
Sbjct: 4 ATEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVV 63
Query: 619 SCIDISHDGTKLWTGGLDNTVRSW-DLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMES 677
+ + S G L + D TVR W + G+ + T+ + S+ + G++LA E
Sbjct: 64 TSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASED 123
Query: 678 SNVEVLH-HTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSK 736
+++V + + Y L+ H V KF+ G+ VS +D + W T +
Sbjct: 124 KSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFS 183
Query: 737 ESSSVLS-CDISADDKYIVTGSGDKKATVYEV 767
+S + D + I + D+ V++V
Sbjct: 184 DSVGFANFVDFNPSGTCIASAGSDQTVKVWDV 215
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 84.0 bits (206), Expect = 5e-16
Identities = 67/262 (25%), Positives = 110/262 (41%), Gaps = 16/262 (6%)
Query: 517 KSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPAC 576
++PI L + + CK P+G TL G + +W++ A L + A
Sbjct: 56 QAPIMLLS--GHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNY-ATLKGHSGAV 112
Query: 577 YALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGA-SCIDISHDGTKLWTGGL 635
L + D + FS +D +AVWD V++ +GHT SC + TG
Sbjct: 113 MELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSD 172
Query: 636 DNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEV--LHHTKPDKYQL 693
D TV+ WD+R+ +Q T Q+ ++ + T + + G ++++V L K Y +
Sbjct: 173 DGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKL-TYTM 231
Query: 694 HLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRT-PYG-----ASIFQSKE---SSSVLSC 744
H V L + G + +S DN + W P+ IFQ ++L C
Sbjct: 232 RGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC 291
Query: 745 DISADDKYIVTGSGDKKATVYE 766
S D I GS D+ V++
Sbjct: 292 SWSPDGSKIAAGSADRFVYVWD 313
Score = 64.3 bits (155), Expect = 4e-10
Identities = 57/229 (24%), Positives = 96/229 (41%), Gaps = 23/229 (10%)
Query: 506 VKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLI-VGGEASTLTIWDLASPTPR 564
V +WD S+ G + + +L +++ SC G L+ G + T+ +WD+ R
Sbjct: 133 VAVWD-SETGER--VKRLK--GHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI-----R 182
Query: 565 IKAELTSSAPACYALAIS--PDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 622
KA + + LA++ + S D +I VWDL L +GH D + +
Sbjct: 183 KKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242
Query: 623 ISHDGTKLWTGGLDNTVRSWDLREGRQLQQ---------HDFTSQIFSLGYCPTGEWLAV 673
+S +G+ L + +DNTVR WD+R ++ H+F + + P G +A
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAA 302
Query: 674 GMESSNVEVLHHT-KPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLL 721
G V V T + Y+L H + + F +S D L
Sbjct: 303 GSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRL 351
>gi|5729852 guanine nucleotide-binding protein, beta-5 subunit
isoform a [Homo sapiens]
Length = 353
Score = 75.1 bits (183), Expect = 2e-13
Identities = 68/299 (22%), Positives = 123/299 (41%), Gaps = 23/299 (7%)
Query: 482 HG-EVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD 540
HG +V+C + R V + G V +WD S +K + C ++ +C P
Sbjct: 62 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWD-SFTTNKEHAVTMPC----TWVMACAYAPS 116
Query: 541 GRTLIVGGEASTLTIWDLA-------SPTPRIKAELTSSAPACYALAISPDAKVCFSCCS 593
G + GG + +++ L + + A T+ AC + + +
Sbjct: 117 GCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSAC---SFTNSDMQILTASG 173
Query: 594 DGNIAVWDLHNQTLVRQFQGHTDGASCIDI--SHDGTKLWTGGLDNTVRSWDLREGRQLQ 651
DG A+WD+ + L++ F GH C+D+ S G +GG D WD+R G+ +Q
Sbjct: 174 DGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQ 233
Query: 652 QHD-FTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVL---SLKFAY 707
+ S I S+ Y P+G+ A G + + + + ++ ES + S+ F+
Sbjct: 234 AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSL 293
Query: 708 CGKWFVSTGKDNLLNAWRTPYGASI-FQSKESSSVLSCDISADDKYIVTGSGDKKATVY 765
G+ + D +N W G+ + + V + +S D +GS D V+
Sbjct: 294 SGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 32.7 bits (73), Expect = 1.3
Identities = 36/173 (20%), Positives = 67/173 (38%), Gaps = 17/173 (9%)
Query: 609 RQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFT---SQIFSLGYC 665
R +GH + C+D D ++ + D V WD ++H T + + + Y
Sbjct: 57 RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD--SFTTNKEHAVTMPCTWVMACAYA 114
Query: 666 PTGEWLAVGMESSNVEVL-------HHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKD 718
P+G +A G + V + K + +H + + + F ++ D
Sbjct: 115 PSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGD 174
Query: 719 NLLNAWRTPYGASIFQS--KESSSVLSCDISADD--KYIVTGSGDKKATVYEV 767
W G + QS + VL D++ + V+G DKKA V+++
Sbjct: 175 GTCALWDVESG-QLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 226
>gi|20336270 guanine nucleotide-binding protein, beta-5 subunit
isoform b [Homo sapiens]
Length = 395
Score = 75.1 bits (183), Expect = 2e-13
Identities = 68/299 (22%), Positives = 123/299 (41%), Gaps = 23/299 (7%)
Query: 482 HG-EVVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD 540
HG +V+C + R V + G V +WD S +K + C ++ +C P
Sbjct: 104 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWD-SFTTNKEHAVTMPC----TWVMACAYAPS 158
Query: 541 GRTLIVGGEASTLTIWDLA-------SPTPRIKAELTSSAPACYALAISPDAKVCFSCCS 593
G + GG + +++ L + + A T+ AC + + +
Sbjct: 159 GCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSAC---SFTNSDMQILTASG 215
Query: 594 DGNIAVWDLHNQTLVRQFQGHTDGASCIDI--SHDGTKLWTGGLDNTVRSWDLREGRQLQ 651
DG A+WD+ + L++ F GH C+D+ S G +GG D WD+R G+ +Q
Sbjct: 216 DGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQ 275
Query: 652 QHD-FTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVL---SLKFAY 707
+ S I S+ Y P+G+ A G + + + + ++ ES + S+ F+
Sbjct: 276 AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSL 335
Query: 708 CGKWFVSTGKDNLLNAWRTPYGASI-FQSKESSSVLSCDISADDKYIVTGSGDKKATVY 765
G+ + D +N W G+ + + V + +S D +GS D V+
Sbjct: 336 SGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
Score = 32.7 bits (73), Expect = 1.3
Identities = 36/173 (20%), Positives = 67/173 (38%), Gaps = 17/173 (9%)
Query: 609 RQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFT---SQIFSLGYC 665
R +GH + C+D D ++ + D V WD ++H T + + + Y
Sbjct: 99 RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD--SFTTNKEHAVTMPCTWVMACAYA 156
Query: 666 PTGEWLAVGMESSNVEVL-------HHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKD 718
P+G +A G + V + K + +H + + + F ++ D
Sbjct: 157 PSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGD 216
Query: 719 NLLNAWRTPYGASIFQS--KESSSVLSCDISADD--KYIVTGSGDKKATVYEV 767
W G + QS + VL D++ + V+G DKKA V+++
Sbjct: 217 GTCALWDVESG-QLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 268
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 73.9 bits (180), Expect = 5e-13
Identities = 57/213 (26%), Positives = 92/213 (43%), Gaps = 6/213 (2%)
Query: 552 TLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQF 611
++ +W L S P A++ + P + + C D + +WDL Q +
Sbjct: 304 SVKLWSLDSDEP--VADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQ 361
Query: 612 QGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQ-QHDFTSQIFSLGYCPTGEW 670
+GH+ G I DG+ TGGLD R WDLR GR + +I+ + + P G
Sbjct: 362 EGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYH 421
Query: 671 LAVGMESSNVEVLH-HTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGK-DNLLNAWRTPY 728
+A G + +V + Y + H++ V +KF F+ TG DN W P
Sbjct: 422 IATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPG 481
Query: 729 GASI-FQSKESSSVLSCDISADDKYIVTGSGDK 760
+ + + V+ DIS+D + I T S D+
Sbjct: 482 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDR 514
Score = 40.4 bits (93), Expect = 0.006
Identities = 50/248 (20%), Positives = 78/248 (31%), Gaps = 51/248 (20%)
Query: 529 DNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVC 588
D I C P+ + L + +W + P + L A+ P + V
Sbjct: 231 DRPISYCHFSPNSKMLATACWSGLCKLWSV--PDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 589 F--------SCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVR 640
SC +DG++ +W L + V +GHT + + G L T D + R
Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348
Query: 641 SWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCV 700
WDL + E+LH H V
Sbjct: 349 LWDLE--------------------------------AQEEILHQEG--------HSMGV 368
Query: 701 LSLKFAYCGKWFVSTGKDNLLNAWRTPYGASI-FQSKESSSVLSCDISADDKYIVTGSGD 759
+ F G + G D W G I F + + S + +I TGSGD
Sbjct: 369 YDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGD 428
Query: 760 KKATVYEV 767
V+++
Sbjct: 429 NTCKVWDL 436
Score = 30.0 bits (66), Expect = 8.5
Identities = 22/105 (20%), Positives = 37/105 (35%), Gaps = 3/105 (2%)
Query: 539 PDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISP-DAKVCFSCCSDGNI 597
P+G + G +T +WDL R + + + P + D
Sbjct: 417 PNGYHIATGSGDNTCKVWDLRQR--RCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTA 474
Query: 598 AVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSW 642
+W + ++ GH +DIS DG + T D T + W
Sbjct: 475 KIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 73.6 bits (179), Expect = 7e-13
Identities = 61/259 (23%), Positives = 99/259 (38%), Gaps = 40/259 (15%)
Query: 504 GCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEAS-TLTIWDLASPT 562
G +KIW++ ++ + L+ + +R P G ++V TL IWDL
Sbjct: 133 GQIKIWEV-----QTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHG 187
Query: 563 PRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 622
+I+ L+ Y +ISPD + S + ++ +W + + TL+R+ +GH D
Sbjct: 188 KQIQV-LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCD 246
Query: 623 ISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEV 682
S D L T D V WD G +L+
Sbjct: 247 FSPDSALLVTASYDTNVIMWDPYTGERLRS------------------------------ 276
Query: 683 LHHTK--PDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSS 740
LHHT+ P +H S + S+ F+ G + + D LL W I + ++
Sbjct: 277 LHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNG 336
Query: 741 VLSCDISADDKYIVTGSGD 759
L C I TG+ D
Sbjct: 337 -LCCTFFPHGGVIATGTRD 354
Score = 37.7 bits (86), Expect = 0.041
Identities = 41/164 (25%), Positives = 67/164 (40%), Gaps = 12/164 (7%)
Query: 593 SDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTK-LWTGGLDNTVRSWDL-REGRQL 650
+DG I +W++ L+ GH D + + G+ L + D T+R WDL + G+Q+
Sbjct: 131 NDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQI 190
Query: 651 QQHDFTSQ-IFSLGYCPTGEWLAVGMESSNV---EVLHHTKPDKYQLHLHESCVLSLKFA 706
Q Q ++ P L +V + +T K L H+S V+S F+
Sbjct: 191 QVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRK--LEGHQSSVVSCDFS 248
Query: 707 YCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADD 750
V+ D + W PY +S + V D + DD
Sbjct: 249 PDSALLVTASYDTNVIMW-DPYTGERLRSLHHTQV---DPAMDD 288
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 70.1 bits (170), Expect = 7e-12
Identities = 45/191 (23%), Positives = 90/191 (47%), Gaps = 10/191 (5%)
Query: 465 LAGPGIPRHARQINTL-SHGEVVCAVTISNPT-RHVYTGGKGC-VKIWDISQPGSKSPIS 521
+A P + + A ++ + +H V ++ + + R + TGG C V +W I++P ++
Sbjct: 1 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLT 60
Query: 522 QLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAI 581
+ + S +L ++ G ++ ++ +WDL + +I L +L
Sbjct: 61 -----GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA--KILRTLMGHKANICSLDF 113
Query: 582 SPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRS 641
P + S D NI +WD+ + V +++GH+ C+ S DG L + D+TV+
Sbjct: 114 HPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKL 173
Query: 642 WDLREGRQLQQ 652
WDL G+ + +
Sbjct: 174 WDLTAGKMMSE 184
Score = 62.0 bits (149), Expect = 2e-09
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 22/173 (12%)
Query: 482 HGEVVCAVTISNPTRHVYTGGK-GCVKIWDISQP-------GSKSPISQLDCLNRDNYIR 533
H V +V ++ P + G + G +++WD+ G K+ I LD
Sbjct: 62 HTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLD--------- 112
Query: 534 SCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCS 593
P G + G + + + +WD+ + S A C L SPD K S
Sbjct: 113 ---FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC--LRFSPDGKWLASAAD 167
Query: 594 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLRE 646
D + +WDL ++ +F GHT + ++ + L +G D T+R WDL +
Sbjct: 168 DHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
Score = 57.8 bits (138), Expect = 4e-08
Identities = 36/177 (20%), Positives = 76/177 (42%), Gaps = 3/177 (1%)
Query: 594 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQ- 652
D + +W ++ + GHT + ++ + G ++R WDL + L+
Sbjct: 42 DCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL 101
Query: 653 HDFTSQIFSLGYCPTGEWLAVGMESSNVEVLH-HTKPDKYQLHLHESCVLSLKFAYCGKW 711
+ I SL + P GE++A G + +N+++ K ++ H V L+F+ GKW
Sbjct: 102 MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKW 161
Query: 712 FVSTGKDNLLNAWRTPYGASIFQ-SKESSSVLSCDISADDKYIVTGSGDKKATVYEV 767
S D+ + W G + + + V + ++ + +GS D+ +++
Sbjct: 162 LASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Score = 46.6 bits (109), Expect = 9e-05
Identities = 38/170 (22%), Positives = 69/170 (40%), Gaps = 17/170 (10%)
Query: 480 LSHGEVVCAVTISNPTRHVYTGGKGC-VKIWDISQPGSKSPISQLDCLNR----DNYIRS 534
+ H +C++ V +G + +K+WDI + G C+ R +R
Sbjct: 102 MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKG---------CVFRYRGHSQAVRC 152
Query: 535 CKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSD 594
+ PDG+ L + T+ +WDL + ++ +E + P+ + S SD
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAG--KMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
Query: 595 GNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDN-TVRSWD 643
I WDL +V +G + + DG L++G D+ V W+
Sbjct: 211 RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260
>gi|5174447 guanine nucleotide binding protein (G protein), beta
polypeptide 2-like 1 [Homo sapiens]
Length = 317
Score = 68.9 bits (167), Expect = 2e-11
Identities = 52/205 (25%), Positives = 86/205 (41%), Gaps = 11/205 (5%)
Query: 469 GIPRHARQINTLSHGEVVCAVTISNPTRHVYTGG-KGCVKIWDISQPGSKSPISQLDCLN 527
GIP+ A + H V V IS+ + +G G +++WD++ + +
Sbjct: 53 GIPQRALR----GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRF-----VG 103
Query: 528 RDNYIRSCKLLPDGRTLIVGGEASTLTIWD-LASPTPRIKAELTSSAPACYALAISPDAK 586
+ S D R ++ G T+ +W+ L ++ E S +C + +
Sbjct: 104 HTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNP 163
Query: 587 VCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLRE 646
+ SC D + VW+L N L GHT + + +S DG+ +GG D WDL E
Sbjct: 164 IIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNE 223
Query: 647 GRQLQQHDFTSQIFSLGYCPTGEWL 671
G+ L D I +L + P WL
Sbjct: 224 GKHLYTLDGGDIINALCFSPNRYWL 248
Score = 46.6 bits (109), Expect = 9e-05
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 23/180 (12%)
Query: 481 SHGEVVCAVTISNPTRH---VYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKL 537
SH E V V S + + V G VK+W+++ K+ + + Y+ + +
Sbjct: 146 SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT-----NHIGHTGYLNTVTV 200
Query: 538 LPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDG-N 596
PDG GG+ +WDL + AL SP+ + C + G +
Sbjct: 201 SPDGSLCASGGKDGQAMLWDLNEGKHLYTLD---GGDIINALCFSPNRY--WLCAATGPS 255
Query: 597 IAVWDLHNQTLVRQFQGHTDGAS-------CIDI--SHDGTKLWTGGLDNTVRSWDLREG 647
I +WDL + +V + + S C + S DG L+ G DN VR W + G
Sbjct: 256 IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 315
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 68.6 bits (166), Expect = 2e-11
Identities = 56/264 (21%), Positives = 104/264 (39%), Gaps = 14/264 (5%)
Query: 468 PGIPRHARQINTLSHGEVVCAVTIS-NPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCL 526
P P +A + H + V +V S N + +KIW + IS
Sbjct: 30 PVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTIS----- 84
Query: 527 NRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAK 586
I D L+ + TL IWD++S + L + + +P +
Sbjct: 85 GHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSG--KCLKTLKGHSNYVFCCNFNPQSN 142
Query: 587 VCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLRE 646
+ S D ++ +WD+ ++ H+D S + + DG+ + + D R WD
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTAS 202
Query: 647 GRQLQQ--HDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPD---KYQLHLHESCVL 701
G+ L+ D + + + P G+++ + +++ ++K Y H +E +
Sbjct: 203 GQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 702 SLKFAYCG-KWFVSTGKDNLLNAW 724
F+ G KW VS +DNL+ W
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIW 286
Score = 53.9 bits (128), Expect = 5e-07
Identities = 46/210 (21%), Positives = 82/210 (39%), Gaps = 4/210 (1%)
Query: 561 PTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASC 620
P +K L A ++ SP+ + S +D I +W ++ + GH G S
Sbjct: 33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISD 92
Query: 621 IDISHDGTKLWTGGLDNTVRSWDLREGRQLQQ-HDFTSQIFSLGYCPTGEWLAVGMESSN 679
+ S D L + D T++ WD+ G+ L+ ++ +F + P + G +
Sbjct: 93 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 152
Query: 680 VEVLH-HTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASI--FQSK 736
V + T L H V ++ F G VS+ D L W T G +
Sbjct: 153 VRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD 212
Query: 737 ESSSVLSCDISADDKYIVTGSGDKKATVYE 766
++ V S + KYI+ + D +++
Sbjct: 213 DNPPVSFVKFSPNGKYILAATLDNTLKLWD 242
Score = 45.8 bits (107), Expect = 1e-04
Identities = 46/193 (23%), Positives = 74/193 (38%), Gaps = 26/193 (13%)
Query: 493 NPTRHVYTGGK--GCVKIWDISQ-------PGSKSPISQLDCLNRDNYIRSCKLLPDGRT 543
NP ++ G V+IWD+ P P+S + NRD G
Sbjct: 138 NPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVH-FNRD-----------GSL 185
Query: 544 LIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLH 603
++ IWD AS +K + P + SP+ K + D + +WD
Sbjct: 186 IVSSSYDGLCRIWDTASGQC-LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS 244
Query: 604 NQTLVRQFQGHTDGASCI--DISHDGTK-LWTGGLDNTVRSWDLREGRQLQQ-HDFTSQI 659
++ + GH + CI + S G K + +G DN V W+L+ +Q+ T +
Sbjct: 245 KGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVV 304
Query: 660 FSLGYCPTGEWLA 672
S PT +A
Sbjct: 305 ISTACHPTENIIA 317
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 68.6 bits (166), Expect = 2e-11
Identities = 56/264 (21%), Positives = 104/264 (39%), Gaps = 14/264 (5%)
Query: 468 PGIPRHARQINTLSHGEVVCAVTIS-NPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCL 526
P P +A + H + V +V S N + +KIW + IS
Sbjct: 30 PVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTIS----- 84
Query: 527 NRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAK 586
I D L+ + TL IWD++S + L + + +P +
Sbjct: 85 GHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSG--KCLKTLKGHSNYVFCCNFNPQSN 142
Query: 587 VCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLRE 646
+ S D ++ +WD+ ++ H+D S + + DG+ + + D R WD
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTAS 202
Query: 647 GRQLQQ--HDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPD---KYQLHLHESCVL 701
G+ L+ D + + + P G+++ + +++ ++K Y H +E +
Sbjct: 203 GQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 702 SLKFAYCG-KWFVSTGKDNLLNAW 724
F+ G KW VS +DNL+ W
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIW 286
Score = 53.9 bits (128), Expect = 5e-07
Identities = 46/210 (21%), Positives = 82/210 (39%), Gaps = 4/210 (1%)
Query: 561 PTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASC 620
P +K L A ++ SP+ + S +D I +W ++ + GH G S
Sbjct: 33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISD 92
Query: 621 IDISHDGTKLWTGGLDNTVRSWDLREGRQLQQ-HDFTSQIFSLGYCPTGEWLAVGMESSN 679
+ S D L + D T++ WD+ G+ L+ ++ +F + P + G +
Sbjct: 93 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 152
Query: 680 VEVLH-HTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASI--FQSK 736
V + T L H V ++ F G VS+ D L W T G +
Sbjct: 153 VRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD 212
Query: 737 ESSSVLSCDISADDKYIVTGSGDKKATVYE 766
++ V S + KYI+ + D +++
Sbjct: 213 DNPPVSFVKFSPNGKYILAATLDNTLKLWD 242
Score = 45.8 bits (107), Expect = 1e-04
Identities = 46/193 (23%), Positives = 74/193 (38%), Gaps = 26/193 (13%)
Query: 493 NPTRHVYTGGK--GCVKIWDISQ-------PGSKSPISQLDCLNRDNYIRSCKLLPDGRT 543
NP ++ G V+IWD+ P P+S + NRD G
Sbjct: 138 NPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVH-FNRD-----------GSL 185
Query: 544 LIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLH 603
++ IWD AS +K + P + SP+ K + D + +WD
Sbjct: 186 IVSSSYDGLCRIWDTASGQC-LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS 244
Query: 604 NQTLVRQFQGHTDGASCI--DISHDGTK-LWTGGLDNTVRSWDLREGRQLQQ-HDFTSQI 659
++ + GH + CI + S G K + +G DN V W+L+ +Q+ T +
Sbjct: 245 KGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVV 304
Query: 660 FSLGYCPTGEWLA 672
S PT +A
Sbjct: 305 ISTACHPTENIIA 317
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 68.6 bits (166), Expect = 2e-11
Identities = 61/257 (23%), Positives = 97/257 (37%), Gaps = 35/257 (13%)
Query: 504 GCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEAS-TLTIWDLASPT 562
G +KIWD+ + L+ ++ +R PDG ++V TL +WDL
Sbjct: 150 GRIKIWDVY-----TGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDG 204
Query: 563 PRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 622
+K L Y+ A SPD+ + S + + +W++ T++R+ +GH D
Sbjct: 205 NMMKV-LRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACD 263
Query: 623 ISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEV 682
S DG L T D V WD G L + F + P A G
Sbjct: 264 FSPDGALLATASYDTRVYIWDPHNGDILME-------FGHLFPPPTPIFAGG-------- 308
Query: 683 LHHTKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVL 742
++ V S+ F++ G S D ++ WR + Q S+ L
Sbjct: 309 ------------ANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPV-QVAPLSNGL 355
Query: 743 SCDISADDKYIVTGSGD 759
C S D + G+ D
Sbjct: 356 CCAFSTDGSVLAAGTHD 372
Score = 53.9 bits (128), Expect = 5e-07
Identities = 49/220 (22%), Positives = 86/220 (39%), Gaps = 24/220 (10%)
Query: 477 INTLSHGEVVCAVTISNPTRHVYTGGKG--CVKIWDISQPGSKSPISQLDCLNRDNYIRS 534
+N + H EVV +T + + +++WD+ G+ + + N++ S
Sbjct: 164 LNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLR----GHQNWVYS 219
Query: 535 CKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSD 594
C PD L G + + +W++ T K E A SPD + + D
Sbjct: 220 CAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE--GHHHDVVACDFSPDGALLATASYD 277
Query: 595 GNIAVWDLHNQTLVRQFQGH---------TDGAS-----CIDISHDGTKLWTGGLDNTVR 640
+ +WD HN ++ +F GH GA+ + SHDG + + D VR
Sbjct: 278 TRVYIWDPHNGDILMEF-GHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVR 336
Query: 641 SWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNV 680
W + E +Q ++ + + G LA G +V
Sbjct: 337 FWRIDEDYPVQVAPLSNGL-CCAFSTDGSVLAAGTHDGSV 375
Score = 38.1 bits (87), Expect = 0.031
Identities = 31/139 (22%), Positives = 59/139 (42%), Gaps = 10/139 (7%)
Query: 593 SDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTK-LWTGGLDNTVRSWDLREGRQLQ 651
++G I +WD++ L+ HT+ + + DG+ L + D T+R WDL++ +
Sbjct: 148 NNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMM 207
Query: 652 Q--HDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKY----QLHLHESCVLSLKF 705
+ + ++S + P L S V + + DKY +L H V++ F
Sbjct: 208 KVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWN---MDKYTMIRKLEGHHHDVVACDF 264
Query: 706 AYCGKWFVSTGKDNLLNAW 724
+ G + D + W
Sbjct: 265 SPDGALLATASYDTRVYIW 283
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 68.6 bits (166), Expect = 2e-11
Identities = 64/289 (22%), Positives = 107/289 (37%), Gaps = 37/289 (12%)
Query: 514 PGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAE----- 568
P S + I N + + + ++ PD + L G + S + +W L S ++K+E
Sbjct: 253 PPSLTTICFYAFYNTEQLLNTAEISPDSKLLAAGFDNSCIKLWSLRS--KKLKSEPHQVD 310
Query: 569 ---------------------------LTSSAPACYALAISPDAKVCFSCCSDGNIAVWD 601
L Y+ D+ SC D +I WD
Sbjct: 311 VSRIHLACDILEEEDDEDDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWD 370
Query: 602 LHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFTSQIF 660
L + T +QGH +DIS +G D T R W L+ + + +
Sbjct: 371 LGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVD 430
Query: 661 SLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL-HESCVLSLKFAYCGKWFVSTGKDN 719
+ + P +LA G V + + + +L H VLSL F+ GK+ S G+D
Sbjct: 431 CVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQ 490
Query: 720 LLNAWRTPYGASIFQSK-ESSSVLSCDISADDKYIVTGSGDKKATVYEV 767
L W G + + + ++ S S D I + S D V+++
Sbjct: 491 RLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 539
Score = 66.2 bits (160), Expect = 1e-10
Identities = 61/241 (25%), Positives = 95/241 (39%), Gaps = 20/241 (8%)
Query: 532 IRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSC 591
+ S + L D L+ E ++ WDL S T + + A + L ISP + S
Sbjct: 345 VYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQ--GHAYPVWDLDISPYSLYFASG 402
Query: 592 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQ 651
D +W +R + GH C+ + L TG D TVR W ++G ++
Sbjct: 403 SHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVR 462
Query: 652 QHDFTSQ---IFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKY-QLHLHESCVLSLKFAY 707
FT + SL + P G++LA E +++ Y +L H + SL F+
Sbjct: 463 L--FTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSP 520
Query: 708 CGKWFVSTGKDNLLNAW--RTPYGASIFQSKES----------SSVLSCDISADDKYIVT 755
S DN + W R Y ++ S S+VLS A + +VT
Sbjct: 521 DSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVT 580
Query: 756 G 756
G
Sbjct: 581 G 581
>gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [Homo
sapiens]
Length = 340
Score = 67.8 bits (164), Expect = 4e-11
Identities = 59/249 (23%), Positives = 98/249 (39%), Gaps = 28/249 (11%)
Query: 528 RDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKV 587
R +++ +C P G + GG + +I++L S +K SA Y
Sbjct: 96 RSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGY---------- 145
Query: 588 CFSCC---SDGNI---------AVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGL 635
SCC D NI A+WD+ F GHT + +S D +G
Sbjct: 146 -LSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGAC 204
Query: 636 DNTVRSWDLREGRQLQQH-DFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLH 694
D + + WD+REG Q S I ++ + P GE + G + ++ + +
Sbjct: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF 264
Query: 695 LHESC---VLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSC-DISADD 750
HES + S+ F+ G+ + D N W + + + +SC ++AD
Sbjct: 265 SHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADG 324
Query: 751 KYIVTGSGD 759
+ TGS D
Sbjct: 325 MAVATGSWD 333
Score = 66.6 bits (161), Expect = 8e-11
Identities = 50/198 (25%), Positives = 82/198 (41%), Gaps = 7/198 (3%)
Query: 531 YIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFS 590
Y+ C+ L D + G+ +T +WD+ T + K C +LA+SPD + S
Sbjct: 145 YLSCCRFLDDNNIVTSSGD-TTCALWDIE--TGQQKTVFVGHTGDCMSLAVSPDFNLFIS 201
Query: 591 CCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQL 650
D + +WD+ T + F GH + I +G + TG D + R +DLR ++L
Sbjct: 202 GACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQEL 261
Query: 651 ---QQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQ-LHLHESCVLSLKFA 706
I S+ + +G L G + N V K ++ L H++ V L
Sbjct: 262 ICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVT 321
Query: 707 YCGKWFVSTGKDNLLNAW 724
G + D+ L W
Sbjct: 322 ADGMAVATGSWDSFLKIW 339
Score = 52.0 bits (123), Expect = 2e-06
Identities = 33/159 (20%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Query: 487 CAVTISNPTRHVYTGGK--GCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTL 544
C +P +++ G K+WD+ + + + ++ I + P+G +
Sbjct: 187 CMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFT-----GHESDINAICFFPNGEAI 241
Query: 545 IVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHN 604
G + ++ ++DL + I S ++A S ++ F+ D N VWD
Sbjct: 242 CTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMK 301
Query: 605 QTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWD 643
V GH + SC+ ++ DG + TG D+ ++ W+
Sbjct: 302 SERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 37.7 bits (86), Expect = 0.041
Identities = 53/220 (24%), Positives = 81/220 (36%), Gaps = 33/220 (15%)
Query: 564 RIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDI 623
R + L YA+ + D+K+ S DG + VWD + V +
Sbjct: 46 RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 624 SHDGTKLWTGGLDNTVRSWDL--REG-----RQLQQH----------DFTSQIFSLGYCP 666
+ G + GGLDN ++L REG R+L H D + + S G
Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTT 165
Query: 667 TGEWLAVGMESSNVEVLH-------HTKPDKYQLHLHESCVLSLKF-----AYCGKWFVS 714
W + V V H PD + L + +C S K C + F
Sbjct: 166 CALWDIETGQQKTVFVGHTGDCMSLAVSPD-FNLFISGACDASAKLWDVREGTCRQTF-- 222
Query: 715 TGKDNLLNA-WRTPYGASIFQSKESSSVLSCDISADDKYI 753
TG ++ +NA P G +I + +S D+ AD + I
Sbjct: 223 TGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELI 262
Score = 33.5 bits (75), Expect = 0.76
Identities = 30/129 (23%), Positives = 59/129 (45%), Gaps = 7/129 (5%)
Query: 644 LREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDK-YQLHLHESCVLS 702
+R R L+ H ++I+++ + + L + + V +K + + L S V++
Sbjct: 45 MRTRRTLRGH--LAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMT 102
Query: 703 LKFAYCGKWFVSTGKDNLLNAWRTPYG-ASIFQSKESSS---VLSCDISADDKYIVTGSG 758
+A G + G DN+ + + ++ S+E S+ LSC DD IVT SG
Sbjct: 103 CAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162
Query: 759 DKKATVYEV 767
D ++++
Sbjct: 163 DTTCALWDI 171
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 67.8 bits (164), Expect = 4e-11
Identities = 43/154 (27%), Positives = 75/154 (48%), Gaps = 8/154 (5%)
Query: 539 PDGRTLIVGGEASTLTIWDLASPT-PRIKAELTSSAPACYALAISPDAKVCFSCCSDGNI 597
P+ + G T+ +WD+ + RI T ++L SP+ + + +DG +
Sbjct: 637 PNSNYVATGSADRTVRLWDVLNGNCVRI---FTGHKGPIHSLTFSPNGRFLATGATDGRV 693
Query: 598 AVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWD-LREGRQLQQHDFT 656
+WD+ + +V + +GHTD + S DG L +G +DNTVR WD ++ L+ DFT
Sbjct: 694 LLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFT 753
Query: 657 SQIFSLGYCPTGEWLAVG---MESSNVEVLHHTK 687
+ + + L +G +S+ V LH T+
Sbjct: 754 TATGHINLPENSQELLLGTYMTKSTPVVHLHFTR 787
Score = 52.0 bits (123), Expect = 2e-06
Identities = 51/233 (21%), Positives = 92/233 (39%), Gaps = 13/233 (5%)
Query: 549 EASTLTIWDLASPT--PRIKAELTSS--------APACYALAISPDAKVCFSCCSDGNIA 598
+AS L++ D S RI E T+S + Y + SPD S DG +
Sbjct: 509 QASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVR 568
Query: 599 VWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFTS 657
+W L T + ++GH S G +GG D R W + L+ +
Sbjct: 569 LWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLA 628
Query: 658 QIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHL-HESCVLSLKFAYCGKWFVSTG 716
+ + P ++A G V + + ++ H+ + SL F+ G++ +
Sbjct: 629 DVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGA 688
Query: 717 KDNLLNAWRTPYGASIFQSK-ESSSVLSCDISADDKYIVTGSGDKKATVYEVI 768
D + W +G + + K + +V S S D + + +GS D +++ I
Sbjct: 689 TDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAI 741
Score = 32.3 bits (72), Expect = 1.7
Identities = 27/115 (23%), Positives = 42/115 (36%), Gaps = 22/115 (19%)
Query: 495 TRHVYTGGKG-CVKIWDISQ-------PGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIV 546
+ +V TG V++WD+ G K PI L P+GR L
Sbjct: 639 SNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLT------------FSPNGRFLAT 686
Query: 547 GGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWD 601
G + +WD+ + EL +L S D ++ S D + +WD
Sbjct: 687 GATDGRVLLWDIGHGL--MVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 14/100 (14%)
Query: 87 TILAQIMPFLSQEHQQQVAQAVERAKQVTMTELNAIIGQ----------QQLQAQHLSHA 136
T+LA ++ FL Q ++ +A+ R + + E A+ G ++ + LS
Sbjct: 96 TLLA-VLQFLRQSKLREAEEALRR--EAGLLE-EAVAGSGAPGEVDSAGAEVTSALLSRV 151
Query: 137 THGPPVQLPPHPSGLQPPGIPPVTGSSSGLLALGALGSQA 176
T P P P G G V+GS+SG A G +GS A
Sbjct: 152 TASAPGPAAPDPPGTGASGATVVSGSASGPAAPGKVGSVA 191
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,967,421
Number of Sequences: 37866
Number of extensions: 1886247
Number of successful extensions: 13740
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 227
Number of HSP's successfully gapped in prelim test: 882
Number of HSP's that attempted gapping in prelim test: 9418
Number of HSP's gapped (non-prelim): 4233
length of query: 769
length of database: 18,247,518
effective HSP length: 110
effective length of query: 659
effective length of database: 14,082,258
effective search space: 9280208022
effective search space used: 9280208022
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.