Guide to the Human Genome
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Search of human proteins with 157266298

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157266298 anti-Mullerian hormone [Homo sapiens]
         (560 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157266298 anti-Mullerian hormone [Homo sapiens]                   1129   0.0  
gi|110349792 growth differentiation factor 1 [Homo sapiens]            64   3e-10
gi|61835232 growth differentiation factor 7 preproprotein [Homo ...    51   2e-06
gi|5031613 growth differentiation factor 11 precursor [Homo sapi...    49   9e-06
gi|48475062 growth differentiation factor 6 precursor [Homo sapi...    48   2e-05
gi|13899338 activin beta E [Homo sapiens]                              48   2e-05
gi|4885259 myostatin [Homo sapiens]                                    48   3e-05
gi|4503969 growth differentiation factor 5 preproprotein [Homo s...    47   4e-05
gi|7705308 growth differentiation factor 2 [Homo sapiens]              47   4e-05
gi|4758826 neurturin preproprotein [Homo sapiens]                      47   5e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   1e-04
gi|154146199 sal-like 3 [Homo sapiens]                                 46   1e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         45   2e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    44   3e-04
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         44   4e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   5e-04
gi|7656928 bone morphogenetic protein 10 preproprotein [Homo sap...    44   5e-04
gi|157276597 bone morphogenetic protein 4 preproprotein [Homo sa...    43   7e-04
gi|157276595 bone morphogenetic protein 4 preproprotein [Homo sa...    43   7e-04
gi|157276593 bone morphogenetic protein 4 preproprotein [Homo sa...    43   7e-04
gi|4502425 bone morphogenetic protein 6 preproprotein [Homo sapi...    43   9e-04
gi|4557369 bone morphogenetic protein 2 preproprotein [Homo sapi...    42   0.001
gi|63025222 transforming growth factor, beta 1 [Homo sapiens]          42   0.001
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]     41   0.003
gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]       41   0.003
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                40   0.004
gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]       40   0.006
gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo ...    40   0.006
gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo ...    40   0.006
gi|153792495 growth differentiation factor 15 [Homo sapiens]           40   0.007

>gi|157266298 anti-Mullerian hormone [Homo sapiens]
          Length = 560

 Score = 1129 bits (2920), Expect = 0.0
 Identities = 560/560 (100%), Positives = 560/560 (100%)

Query: 1   MRDLPLTSLALVLSALGALLGTEALRAEEPAVGTSGLIFREDLDWPPGSPQEPLCLVALG 60
           MRDLPLTSLALVLSALGALLGTEALRAEEPAVGTSGLIFREDLDWPPGSPQEPLCLVALG
Sbjct: 1   MRDLPLTSLALVLSALGALLGTEALRAEEPAVGTSGLIFREDLDWPPGSPQEPLCLVALG 60

Query: 61  GDSNGSSSPLRVVGALSAYEQAFLGAVQRARWGPRDLATFGVCNTGDRQAALPSLRRLGA 120
           GDSNGSSSPLRVVGALSAYEQAFLGAVQRARWGPRDLATFGVCNTGDRQAALPSLRRLGA
Sbjct: 61  GDSNGSSSPLRVVGALSAYEQAFLGAVQRARWGPRDLATFGVCNTGDRQAALPSLRRLGA 120

Query: 121 WLRDPGGQRLVVLHLEEVTWEPTPSLRFQEPPPGGAGPPELALLVLYPGPGPEVTVTRAG 180
           WLRDPGGQRLVVLHLEEVTWEPTPSLRFQEPPPGGAGPPELALLVLYPGPGPEVTVTRAG
Sbjct: 121 WLRDPGGQRLVVLHLEEVTWEPTPSLRFQEPPPGGAGPPELALLVLYPGPGPEVTVTRAG 180

Query: 181 LPGAQSLCPSRDTRYLVLAVDRPAGAWRGSGLALTLQPRGEDSRLSTARLQALLFGDDHR 240
           LPGAQSLCPSRDTRYLVLAVDRPAGAWRGSGLALTLQPRGEDSRLSTARLQALLFGDDHR
Sbjct: 181 LPGAQSLCPSRDTRYLVLAVDRPAGAWRGSGLALTLQPRGEDSRLSTARLQALLFGDDHR 240

Query: 241 CFTRMTPALLLLPRSEPAPLPAHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRA 300
           CFTRMTPALLLLPRSEPAPLPAHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRA
Sbjct: 241 CFTRMTPALLLLPRSEPAPLPAHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRA 300

Query: 301 LRVPPARASAPRLALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDP 360
           LRVPPARASAPRLALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDP
Sbjct: 301 LRVPPARASAPRLALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDP 360

Query: 361 APLHDPTSAPWATALARRVAAELQAAAAELRSLPGLPPATAPLLARLLALCPGGPGGLGD 420
           APLHDPTSAPWATALARRVAAELQAAAAELRSLPGLPPATAPLLARLLALCPGGPGGLGD
Sbjct: 361 APLHDPTSAPWATALARRVAAELQAAAAELRSLPGLPPATAPLLARLLALCPGGPGGLGD 420

Query: 421 PLRALLLLKALQGLRVEWRGRDPRGPGRAQRSAGATAADGPCALRELSVDLRAERSVLIP 480
           PLRALLLLKALQGLRVEWRGRDPRGPGRAQRSAGATAADGPCALRELSVDLRAERSVLIP
Sbjct: 421 PLRALLLLKALQGLRVEWRGRDPRGPGRAQRSAGATAADGPCALRELSVDLRAERSVLIP 480

Query: 481 ETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLLISLS 540
           ETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLLISLS
Sbjct: 481 ETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLLISLS 540

Query: 541 EERISAHHVPNMVATECGCR 560
           EERISAHHVPNMVATECGCR
Sbjct: 541 EERISAHHVPNMVATECGCR 560


>gi|110349792 growth differentiation factor 1 [Homo sapiens]
          Length = 372

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 92/304 (30%), Positives = 108/304 (35%), Gaps = 53/304 (17%)

Query: 273 PPRPSAELEESPPSADPFLETLTRLVRALRVPPA-RASAPRLALD-PDALAGFPQGLVNL 330
           P R +      P SA       T +     V PA R S  RL L    A A  P+G   L
Sbjct: 106 PDRGAPTRASEPASAAGHCPEWTVVFDLSAVEPAERPSRARLELRFAAAAAAAPEGGWEL 165

Query: 331 SDPAALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWATALARRVAAELQAAAAEL 390
           S   A +    G +P  +LLR      G P                  V AEL  AA   
Sbjct: 166 SVAQAGQGA--GADPGPVLLRQLVPALGPP------------------VRAELLGAAWAR 205

Query: 391 RSLPGLPPATAPLLARL-LALCPGGPGGLGDPLRALLLLKALQGLRVEWRGRDPR---GP 446
                   A+ P   RL LAL P  P        A LLL  L          DPR     
Sbjct: 206 N-------ASWPRSLRLALALRPRAPAACARLAEASLLLVTL----------DPRLCHPL 248

Query: 447 GRAQRSAGATAADGP---CALRELSVDLRA---ERSVLIPETYQANNCQGVCGWP---QS 497
            R +R A      GP   C  R L V  R     R V+ P  + AN CQG C  P     
Sbjct: 249 ARPRRDAEPVLGGGPGGACRARRLYVSFREVGWHRWVIAPRGFLANYCQGQCALPVALSG 308

Query: 498 DRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAG-KLLISLSEERISAHHVPNMVATE 556
              P   NH VL   M A     A  PCCVP   +   +L   + + +      +MV  E
Sbjct: 309 SGGPPALNHAVLRALMHAAAPGAADLPCCVPARLSPISVLFFDNSDNVVLRQYEDMVVDE 368

Query: 557 CGCR 560
           CGCR
Sbjct: 369 CGCR 372


>gi|61835232 growth differentiation factor 7 preproprotein [Homo
           sapiens]
          Length = 450

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 51/192 (26%), Positives = 78/192 (40%), Gaps = 25/192 (13%)

Query: 374 ALARRVAAELQAAAAELRSLPGLPPATAPLLARLLALCPGGPGGLGDPLRALLLLKALQG 433
           +L R + A+ +A  A L S P   P T     R +       GG      AL   +  QG
Sbjct: 279 SLFREIRAQARALGAALASEPLPDPGTGTASPRAVI------GGRRRRRTALAGTRTAQG 332

Query: 434 LRVEWRGRDPRGPGRAQRSAGATAADGPCALRELSVDLRA---ERSVLIPETYQANNCQG 490
                 G   RG GR  RS         C+ + L VD +    +  ++ P  Y+A +C+G
Sbjct: 333 SG----GGAGRGHGRRGRSR--------CSRKPLHVDFKELGWDDWIIAPLDYEAYHCEG 380

Query: 491 VCGWP-QSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAG-KLLISLSEERISAHH 548
           +C +P +S   P   NH ++   + +     A   CCVP   +   +L   +   +    
Sbjct: 381 LCDFPLRSHLEPT--NHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQ 438

Query: 549 VPNMVATECGCR 560
             +MV   CGCR
Sbjct: 439 YEDMVVEACGCR 450


>gi|5031613 growth differentiation factor 11 precursor [Homo
           sapiens]
          Length = 407

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 43/159 (27%), Positives = 70/159 (44%), Gaps = 28/159 (17%)

Query: 408 LALCPGGPGGLGDPLRALLLLKALQGLRVEWRGRDPRGPGRAQRSAGAT----AADGPCA 463
           LA+   GPG  G  L   + L+ L+  +            R++R+ G      +++  C 
Sbjct: 269 LAVTSLGPGAEG--LHPFMELRVLENTK------------RSRRNLGLDCDEHSSESRCC 314

Query: 464 LRELSVDLRAERS--VLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALA 521
              L+VD  A     ++ P+ Y+AN C G C +    + P    H  L+ +   RG+A  
Sbjct: 315 RYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYP----HTHLVQQANPRGSA-- 368

Query: 522 RPPCCVPTAYAG-KLLISLSEERISAHHVPNMVATECGC 559
             PCC PT  +   +L    +++I    +P MV   CGC
Sbjct: 369 -GPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGC 406


>gi|48475062 growth differentiation factor 6 precursor [Homo
           sapiens]
          Length = 455

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 16/129 (12%)

Query: 446 PGRAQRSAGATAADGP---------CALRELSVDLRA---ERSVLIPETYQANNCQGVCG 493
           PGR +R     +  G          C+ + L V+ +    +  ++ P  Y+A +C+GVC 
Sbjct: 329 PGRRRRRTAFASRHGKRHGKKSRLRCSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCD 388

Query: 494 WP-QSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAG-KLLISLSEERISAHHVPN 551
           +P +S   P   NH ++   M +       P CCVPT      +L   +   +      +
Sbjct: 389 FPLRSHLEPT--NHAIIQTLMNSMDPGSTPPSCCVPTKLTPISILYIDAGNNVVYKQYED 446

Query: 552 MVATECGCR 560
           MV   CGCR
Sbjct: 447 MVVESCGCR 455


>gi|13899338 activin beta E [Homo sapiens]
          Length = 350

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 42/133 (31%), Positives = 56/133 (42%), Gaps = 9/133 (6%)

Query: 434 LRVEWRGRDPRGPGRAQRSAGATAADGP-CALRELSVDLRA---ERSVLIPETYQANNCQ 489
           L ++ R  +P G GRA+R         P C  R+  VD +       +L PE YQ N C 
Sbjct: 219 LELKIRANEP-GAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCS 277

Query: 490 GVCGWPQSDRNPRYGN--HVVLLLKMQARGAALARPPCCVPTAYAGKLLISLSEE-RISA 546
           G C  P    +P      H  +   ++A     A   CCVPTA     L+ L     +  
Sbjct: 278 GQCP-PHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVK 336

Query: 547 HHVPNMVATECGC 559
             VP+MV   CGC
Sbjct: 337 TDVPDMVVEACGC 349


>gi|4885259 myostatin [Homo sapiens]
          Length = 375

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 14/121 (11%)

Query: 446 PGRAQRSAGAT----AADGPCALRELSVDLRAERS--VLIPETYQANNCQGVCGWPQSDR 499
           P R++R  G      + +  C    L+VD  A     ++ P+ Y+AN C G C +    +
Sbjct: 261 PKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQK 320

Query: 500 NPRYGNHVVLLLKMQARGAALARPPCCVPTAYAG-KLLISLSEERISAHHVPNMVATECG 558
            P    H  L+ +   RG+A    PCC PT  +   +L    +E+I    +P MV   CG
Sbjct: 321 YP----HTHLVHQANPRGSA---GPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCG 373

Query: 559 C 559
           C
Sbjct: 374 C 374


>gi|4503969 growth differentiation factor 5 preproprotein [Homo
           sapiens]
          Length = 501

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 7/104 (6%)

Query: 462 CALRELSV---DLRAERSVLIPETYQANNCQGVCGWP-QSDRNPRYGNHVVLLLKMQARG 517
           C+ + L V   D+  +  ++ P  Y+A +C+G+C +P +S   P   NH V+   M +  
Sbjct: 400 CSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPT--NHAVIQTLMNSMD 457

Query: 518 AALARPPCCVPTAYAG-KLLISLSEERISAHHVPNMVATECGCR 560
                P CCVPT  +   +L   S   +      +MV   CGCR
Sbjct: 458 PESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR 501


>gi|7705308 growth differentiation factor 2 [Homo sapiens]
          Length = 429

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 448 RAQRSAGATAADGPCALRELSVDLRAERSVLIPETYQANNCQGVCGWPQSDRNPRYGNHV 507
           R +RSAGA +     +LR    D+  +  ++ P+ Y+A  C+G C +P +D +     H 
Sbjct: 316 RRKRSAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLAD-DVTPTKHA 374

Query: 508 VLLLKMQARGAALARPPCCVPTAYAGKLLISLSEERISA--HHVPNMVATECGCR 560
           ++   +  +        CCVPT  +   ++   +  +    +H   M   ECGCR
Sbjct: 375 IVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGCR 429


>gi|4758826 neurturin preproprotein [Homo sapiens]
          Length = 197

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 55/193 (28%), Positives = 69/193 (35%), Gaps = 21/193 (10%)

Query: 371 WATALARRVAAELQAAAAELRSLPGLPPATAPLLARLLALCPGGPGGLGDPLRALLLLKA 430
           W       ++  L  A   L  LP    A    LA+  AL  G P  +   LR L     
Sbjct: 21  WMCREGLLLSHRLGPALVPLHRLPRTLDARIARLAQYRALLQGAPDAM--ELREL----- 73

Query: 431 LQGLRVEWRGRDP---RGPGRAQRSAGATAADGPCALRELSVDL-RAERSVLIPETYQAN 486
                  W GR P   R  G  +R A A     PC LREL V +          ET    
Sbjct: 74  -----TPWAGRPPGPRRRAGPRRRRARARLGARPCGLRELEVRVSELGLGYASDETVLFR 128

Query: 487 NCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLLISLSEERISA 546
            C G C    + R    G    L  + + R   +   PCC PTAY  +  +S  +     
Sbjct: 129 YCAGAC--EAAARVYDLGLR-RLRQRRRLRRERVRAQPCCRPTAYEDE--VSFLDAHSRY 183

Query: 547 HHVPNMVATECGC 559
           H V  + A EC C
Sbjct: 184 HTVHELSARECAC 196


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 105/418 (25%), Positives = 136/418 (32%), Gaps = 45/418 (10%)

Query: 142 PTPSLRFQEPPPGGAGPPELALLVLYPGPGPEVTVTRAGLPGAQSLCPSRDTRYLVLAVD 201
           P+P L     PP  A PP LAL  L   P P  +   + L       P+    +L+ A  
Sbjct: 607 PSPPLSPLATPPPQA-PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 665

Query: 202 RPAGAWRGSGLALTLQPRGED--SRLSTARLQALLFGDDHRCFTRMTPALLLLPRSEPAP 259
            P  +     +     P      S  +T   QA              P+L   P   P  
Sbjct: 666 SPPPS---PPVQAPFSPPASPPVSPSATPPSQA-------------PPSLAAPPLQVPPS 709

Query: 260 LPAHGQLDTVPFPPPRPS-------AELEESPPSADPFLETLTRLVRALRVPPARASAPR 312
            PA   +     PPP+          ++  SPP++ P   + T      RVPP  A AP 
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT---PPPRVPPLLA-APP 765

Query: 313 LALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWA 372
           L + P   A  P   +    P A   L     PL  L  P A+  G  AP     S P  
Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPAL--ATPPLQALPSPPASFPGQ-APFSPSASLP-M 821

Query: 373 TALARRVAAELQAAAAELRSLPGLPPATAPLLARLLALCPGGPGGLGDPLRALLLLKALQ 432
           + LA          AA L  +P  PPA+  L A      PG    +  P   L L     
Sbjct: 822 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 881

Query: 433 GLRVEWRGRDPRGPGRAQRSAGATAADGPCALRELSVDLRAERSVLIPETYQANNCQGVC 492
                       GP  A  S+ AT+   P  LR          +   P   +   C    
Sbjct: 882 PPPSRSPSSTLSGPDLAGHSSSATST--PEELRGYDSGPEGGAAASPPPDAELAACH-PA 938

Query: 493 GWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLLISLSEERISAHHVP 550
            W +    P        L    A GA L  PP   P +  G   I  +E   SA   P
Sbjct: 939 AWSRGPAPP--------LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 988



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 45/155 (29%), Positives = 59/155 (38%), Gaps = 10/155 (6%)

Query: 257 PAPLPAHGQLDTVPFPPPRPSAELEESPPSADPFLET--LTRL----VRALRVPPARASA 310
           PAP P       +  PPP   + +   PP A P L +  L  L    +  L  PP +A  
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA-P 622

Query: 311 PRLALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDP--APLHDPTS 368
           P LAL P      P     LS  A           + LL  P +     P  AP   P S
Sbjct: 623 PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682

Query: 369 APWATALARRVAAELQAAAAELRSLPGLPPATAPL 403
            P + +      A    AA  L+ +P  PPA+ P+
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQ-VPPSPPASPPM 716



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 23/152 (15%)

Query: 257 PAPLPAHGQLDT-VPFPPPRPSA----ELEESPPSADPFLETLTRLVRALRVPPARASAP 311
           PA LP    L T +P  PP PSA    +   SPP+  P     +     ++ PP+  + P
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387

Query: 312 RLALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSAPW 371
            + +        P  L + S  A          P  L L    ATT   +P    T + +
Sbjct: 388 PIQV--------PHSLTSPSLQA---------PPSPLALSSLQATTSLGSPTLQATHS-F 429

Query: 372 ATALARRVAAELQAAAAELRSLPGLPPATAPL 403
            T   R+  A L + +    + P  PP  APL
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 44/166 (26%), Positives = 55/166 (33%), Gaps = 21/166 (12%)

Query: 253 PRSEPAPLPAHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPR 312
           PR   +    H   +  P    RPSA      P++     + T L    R  P+    PR
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264

Query: 313 LALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAAT---------------- 356
               P      P+GL  L  P       D    L  L     AT                
Sbjct: 265 APAHPSQPK--PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDN 322

Query: 357 TGDPAPLHDPTSAPWATALARRVAAELQAAAAELRSLPGLPPATAP 402
              P P   P S P AT L   +A    +A   L++LP  PPAT P
Sbjct: 323 AATPLPATLPPSPPLATPLP--LAPPSPSAPPSLQTLPS-PPATPP 365


>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 82/300 (27%), Positives = 104/300 (34%), Gaps = 66/300 (22%)

Query: 126 GGQRLVVLHLEEVTWEPTPSLRFQEPPPGGAGPPELALLVLYPGPGPEVTVTRAGLPGAQ 185
           G  R V    E +  EP    R   PPP    PP  A    Y  P   VT+         
Sbjct: 122 GEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPA----YGAPSTNVTLEAL------ 171

Query: 186 SLCPSRDTRYLVLAVDRPA----GAWRGSGLALTLQPRGEDSRLSTARLQALLFGDDHRC 241
                  T+  V    + A    G+  G G+A    P      L   +L AL     H+ 
Sbjct: 172 -----LSTKVAVAQFSQGARAAGGSGAGGGVAAAAVP------LILEQLMALQQQQIHQ- 219

Query: 242 FTRMTPALLLLPRSEPAPLPAHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRAL 301
                  L L+ +          Q+  +  PPPRPS     +P +               
Sbjct: 220 -------LQLIEQ-------IRSQVALMQRPPPRPSLSPAAAPSAPG------------- 252

Query: 302 RVPPARASAPRLALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPT--AATTGD 359
              PA +  P LA  P   AG P   +  S PAA     +G +P   L RP   A+T G 
Sbjct: 253 ---PAPSQLPGLAALP-LSAGAPAAAIAGSGPAA-PAAFEGAQP---LSRPESGASTPGG 304

Query: 360 PAPLHDPTSAPWATALARRVAAEL-QAAAAELRSLPGLPPATAPLLARLLALCPGGPGGL 418
           PA    P +   A A A    A   Q+AA+        PPA AP    LL   PG P  L
Sbjct: 305 PAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAP--GSLLGAAPGLPSPL 362


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 88/334 (26%), Positives = 115/334 (34%), Gaps = 80/334 (23%)

Query: 127  GQRLVVLHLEEVTWEPTPSLRFQEPPPGGAGPPELALLVLYPGPGPEVTVTRAGLPGAQS 186
            G+ +VV++       P P      PPPG    PEL+     PGP P+V      LP +  
Sbjct: 1006 GRTVVVVNNPRAPLGPVPV----RPPPG----PELSAQPT-PGPVPQV------LPASLM 1050

Query: 187  LCPSRDTRYLVLAVDRPAGAWRGSGLALTLQPRGEDSRLSTARLQALLFGDDHRCFTRMT 246
            +  S     L+     PA    G  L   LQP              +L G         T
Sbjct: 1051 VSASPAGPPLI-----PASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRP----PT 1101

Query: 247  PALLLLPRSEPAPLPAHGQLDTVPFPPPRPSAELEES--------PPSADPFLETLTRLV 298
            P L L P + PAP+         P PPP  S+ L+          PP+A     T T   
Sbjct: 1102 PTLSLKP-TPPAPVRLS------PAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATA 1154

Query: 299  RALRVPPARASAPRLALDPDALAGFPQG-LVNLSDPAALERL----LDGEEPLLLLLRPT 353
                VP    +  RL L PD  A  P G +V++   A+L +       G +PL   ++  
Sbjct: 1155 TTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGN 1214

Query: 354  AAT----------TGDPAPL-------------HDPTSAPWATALARRVAAELQAAAAEL 390
              T           G P PL             H   S P   AL + VA         +
Sbjct: 1215 KLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAP--TPGPTPV 1272

Query: 391  RSLPGLPPATAPLLARLLALCPGGPGGLGDPLRA 424
              LP   P+T P            P GL  PL A
Sbjct: 1273 SVLPSSTPSTTP-----------APTGLSLPLAA 1295



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 69/279 (24%), Positives = 95/279 (34%), Gaps = 20/279 (7%)

Query: 152  PPGGAGPPELALLVLYPGPGPEVTVTRAGLPGAQSLCPSRDTR------------YLVLA 199
            PPG   PP  A            T   A  P  Q L  S D +             L   
Sbjct: 1134 PPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASL 1193

Query: 200  VDRPAGAWRGSGLALTLQPRGEDSRLSTARLQALLFGDDHRCFTRMTPALLLLPRSEPAP 259
              RP  A  G    LT Q +G    L+ A+++ L  G        +   +    +     
Sbjct: 1194 AQRPV-ANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLIS 1252

Query: 260  LPAHGQL--DTVPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPRLALDP 317
             PAH  L     P P P P + L  S PS  P    L+  + A +VPP   +     +  
Sbjct: 1253 QPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVN--NTGVVK 1310

Query: 318  DALAGFPQ-GLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWAT-AL 375
              +   P+ GL  +   A   R      P +L  RPT      P P      AP  T  L
Sbjct: 1311 IVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTL 1370

Query: 376  ARRVAAELQAAAAEL-RSLPGLPPATAPLLARLLALCPG 413
             R +   + + + E+  S PG  P T      + +  PG
Sbjct: 1371 VRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPG 1409



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 59/251 (23%), Positives = 82/251 (32%), Gaps = 40/251 (15%)

Query: 159  PELALLVLYPGPGPEVTVTRAGLPGAQSLCPSRDTRYLVLAVDRPAGAWRGSGLALTLQP 218
            P+ A+L   P P        A  PGA  +  S  T   V+A      +  G+ LA     
Sbjct: 1593 PQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMA----PSSTPGTSLASASPV 1648

Query: 219  RGEDSRLSTARLQALLFGDDHRCFTRMTPALLLLPRSEPAPLPAHGQLDTVPFPPPRPSA 278
                  L+ +  Q                   +LP   P+PLP+     T+   P   + 
Sbjct: 1649 PAPTPVLAPSSTQT------------------MLPAPVPSPLPSPASTQTLALAPAL-AP 1689

Query: 279  ELEESPPSADPFLETLTRL----VRALRVPPARASAPRLALDPDALAGFPQGLVNLSDPA 334
             L  S PS    L T         + L + PA +  P  A       G P G       A
Sbjct: 1690 TLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLA 1749

Query: 335  ALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWATALARRVAAELQAAAAELRSLP 394
                L               A+   PAP H  T AP +++ +    A +Q        +P
Sbjct: 1750 PAPPL-------------APASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVP 1796

Query: 395  GLPPATAPLLA 405
             L PA A  LA
Sbjct: 1797 TLGPAAAQTLA 1807



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 49/184 (26%), Positives = 71/184 (38%), Gaps = 46/184 (25%)

Query: 247  PALLLLPRSEPAPLPAHGQLDTVP---FPPPRPSAELEESPPSADPFLETLTRLVRALRV 303
            PAL+ +P S P P+ A   +  +P    P P P +++   PP + P          A   
Sbjct: 2455 PALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQI---PPCSSP----------ACTP 2501

Query: 304  PPARASAPRLALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLL---LLRPTAATTGDP 360
            PPA    P                   + P A   L+    PLLL    +  +A+ T  P
Sbjct: 2502 PPACTPPPA-----------------HTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLP 2544

Query: 361  APLHDPTSAPWATALARRVAAEL-QAAAAELRSLPGLPP--------ATAPLLARLLALC 411
              L  P +   A ALA   + EL   A++E  SL  +PP           P+  + L+L 
Sbjct: 2545 LGLR-PEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLT 2603

Query: 412  PGGP 415
            P  P
Sbjct: 2604 PSAP 2607



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 60/226 (26%), Positives = 75/226 (33%), Gaps = 39/226 (17%)

Query: 168  PGPGPEVTVTRAGLPG-AQSLCPSRDTRYLVLAVDRPAGAWRGSGLALTLQPRGEDSRLS 226
            P P P  T T A  P  A +L  S  ++ L L    P G +    L+LT       S L 
Sbjct: 1671 PLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLT-----PASSLV 1725

Query: 227  TARLQALLFGDDHRCFTRMT----PALLLLPRSEPAPLPAHGQLDTVPFPPPRPSAELEE 282
                Q L            T    PA  L P S   P PAH    T+   P   SA L  
Sbjct: 1726 PTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAH----TLTLAPASSSASL-- 1779

Query: 283  SPPSADPFLETLT-----------RLVRALRVPPARASAPRLALDPDALAGFPQGLVNLS 331
                A   ++TLT              + L + PA   +P  A    +L     G   L 
Sbjct: 1780 ---LAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSP--ASQASSLVVSASGAAPLP 1834

Query: 332  DPAALERLLDGEEPLLLLLR-------PTAATTGDPAPLHDPTSAP 370
                    +  +EP  L LR        TA + G P P   P   P
Sbjct: 1835 VTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPP 1880


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 106/421 (25%), Positives = 133/421 (31%), Gaps = 50/421 (11%)

Query: 142 PTPSLRFQEPPPGGAGPPELALLVLYPGPGPEVTVTRAGLPGAQ---SLCPSRDTRYLVL 198
           P+PS      PP  + PP L  L   P   P    T  G P  Q   S  PS     L  
Sbjct: 298 PSPSA-----PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352

Query: 199 AVDRPAGAWRGSGLALTLQPRGED--SRLSTARLQALLFGDDHRCFTRMTPALLLLPRSE 256
              +   A     L     P      S L+T   QA            +   LL  P S 
Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP---------NALAVHLLQAPFSP 403

Query: 257 PAPLPAHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPRLALD 316
           P   P          PP  PSA    +PPS  P     +     L+VPP+  ++P ++  
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSA----TPPSQAP----PSLAAPPLQVPPSPPASPPMSPS 455

Query: 317 -------PDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSA 369
                  P  LA  P   + L+ P           PL  L  P A+  G  AP     S 
Sbjct: 456 ATPPPQAPPPLAAPP---LQLAKPPPQAPPALATPPLQALPSPPASFPGQ-APFSPSASL 511

Query: 370 PWATALARRVAAELQAAAAELRSLPGLPPATAPLLARLLALCPGGPGGLGDPLRALLLLK 429
           P  + LA          AA L  +P  PPA+  L A      PG    +  P   L L  
Sbjct: 512 P-MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 570

Query: 430 ALQGLRVEWRGRDPRGPGRAQRSAGATAADGPCALRELSVDLRAERSVLIPETYQANNCQ 489
                          GP  A  S+ AT+   P  LR          +   P   +   C 
Sbjct: 571 GPPPPPSRSPSSTLSGPDLAGHSSSATST--PEELRGYDSGPEGGAAASPPPDAELAACH 628

Query: 490 GVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLLISLSEERISAHHV 549
               W +    P        L    A GA L  PP   P +  G   I  +E   SA   
Sbjct: 629 -PAAWSRGPAPP--------LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 679

Query: 550 P 550
           P
Sbjct: 680 P 680



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 42/161 (26%), Positives = 53/161 (32%), Gaps = 13/161 (8%)

Query: 253 PRSEPAPLPAHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPR 312
           PR   +    H   +  P    RPSA      P++     + T L    R  P+    PR
Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 255

Query: 313 LALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDPAP---------- 362
               P      P+GL  L  P       D    L  L     AT    AP          
Sbjct: 256 APAHPSQPK--PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313

Query: 363 -LHDPTSAPWATALARRVAAELQAAAAELRSLPGLPPATAP 402
            L  P + P + A     +  LQA  + L S P  P AT P
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 354



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 73/303 (24%), Positives = 91/303 (30%), Gaps = 55/303 (18%)

Query: 125 PGGQRLVVLHLEEVTWEPTPSLRFQEP-------------PPGGAGPPELALLVLYPGPG 171
           P     + +HL +  + P PS   Q P              P    PP LA   L   P 
Sbjct: 386 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445

Query: 172 PEVTVTRAGLPGAQSLCPSRDTRYLVLAVDRPAGAWRGSGLALTLQPRGEDSRLSTARLQ 231
           P         P +  + PS           +         L L   P      L+T  LQ
Sbjct: 446 P---------PASPPMSPS------ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ 490

Query: 232 ALLFGDDHRCFTRMTP---------ALLLLPRSEPAPLPAHGQLDTVPFPPPRPSAELEE 282
           AL        F    P         + L  P  +  P+ A   L   P PP  P+ +   
Sbjct: 491 AL--PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548

Query: 283 SPPSADPFLETL-TRLVRALR--VPPARASAPRLALDPDALAGFPQGLVNLSDPAALERL 339
            PP+  P       RL  AL    PP  + +P   L    LAG        S P  L   
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT--STPEELRGY 606

Query: 340 LDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWATALARRVAAELQAAAAELRSLPGLPPA 399
             G         P       P P     +A    A +R  A  L    A    LP  PPA
Sbjct: 607 DSG---------PEGGAAASPPP-DAELAACHPAAWSRGPAPPLAFRGAPGAPLP-WPPA 655

Query: 400 TAP 402
           T P
Sbjct: 656 TGP 658


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 98/341 (28%), Positives = 122/341 (35%), Gaps = 52/341 (15%)

Query: 151 PPPGGAGPPELALLVLYPG--PGPEVTVTRAGLPGAQSLCPSRDTRYLVLAVDRPAGAWR 208
           PPPGG GPP      L PG   GP + V         SL P   +  L      P+    
Sbjct: 578 PPPGGPGPP------LAPGEPEGPSLLVA--------SLLPPPPSDLLPPPSAPPSNLLA 623

Query: 209 GSGLALTLQPRGEDSRLSTARLQALLFGDDHRCFTRMTPALLLLPRSEPAPLPA------ 262
                L L P   D    +A       G+       ++P LL  P S P  L A      
Sbjct: 624 SFLPLLALGPTAGDGE-GSAEGAGGPSGEPFSGLGDLSP-LLFPPLSAPPTLIALNSALL 681

Query: 263 HGQLDTVPFPPPRPS--AELEESPPSADPFLETLTRLVRALRVPPARASAPRLALDPDAL 320
              LD     PP+P   +  +  PP++     T      +L   P+ +  P   L P   
Sbjct: 682 AATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLG 741

Query: 321 AGFPQGLVNL-SDPAALERLLDGEEPLL-----LLLRPTAATTGDPAPLHDPTSAPWATA 374
           A     L +L S P AL  LL    PLL     L L P     G P PL +  S+P A  
Sbjct: 742 ASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGG---GAPPPLSE-ASSPLACL 797

Query: 375 LARRVAAELQAAAAELRSLPGLPPATA----PLLARLLALCPGGPGGLGDPLRALLLLKA 430
           L    + ++     E   LP   PA+A    P    L AL P  P G  DP    LL   
Sbjct: 798 LQ---SLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAP--PHGSPDPPVPELLTGR 852

Query: 431 LQGLRVEWRGRDPRG------PGRAQRSAGATAADGPCALR 465
             G R    G   RG      P R  R  G+    G  AL+
Sbjct: 853 GSGKRGRRGGGGLRGINGEARPARG-RKPGSRREPGRLALK 892


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 103/411 (25%), Positives = 129/411 (31%), Gaps = 45/411 (10%)

Query: 152 PPGGAGPPELALLVLYPGPGPEVTVTRAGLPGAQ---SLCPSRDTRYLVLAVDRPAGAWR 208
           PP  + PP L  L   P   P    T  G P  Q   S  PS     L     +   A  
Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401

Query: 209 GSGLALTLQPRGED--SRLSTARLQALLFGDDHRCFTRMTPALLLLPRSEPAPLPAHGQL 266
              L     P      S L+T   QA            +   LL  P S P   P     
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAP---------NALAVHLLQAPFSPPPSPPVQAPF 452

Query: 267 DTVPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPRLALD-------PDA 319
                PP  PSA    +PPS  P     +     L+VPP+  ++P ++         P  
Sbjct: 453 SPPASPPVSPSA----TPPSQAP----PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504

Query: 320 LAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWATALARRV 379
           LA  P   + L+ P           PL  L  P A+  G  AP     S P  + LA   
Sbjct: 505 LAAPP---LQLAKPPPQAPPALATPPLQALPSPPASFPGQ-APFSPSASLP-MSPLATPP 559

Query: 380 AAELQAAAAELRSLPGLPPATAPLLARLLALCPGGPGGLGDPLRALLLLKALQGLRVEWR 439
                  AA L  +P  PPA+  L A      PG    +  P   L L            
Sbjct: 560 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619

Query: 440 GRDPRGPGRAQRSAGATAADGPCALRELSVDLRAERSVLIPETYQANNCQGVCGWPQSDR 499
                GP  A  S+ AT+   P  LR          +   P   +   C     W +   
Sbjct: 620 SSTLSGPDLAGHSSSATST--PEELRGYDSGPEGGAAASPPPDAELAACH-PAAWSRGPA 676

Query: 500 NPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLLISLSEERISAHHVP 550
            P        L    A GA L  PP   P +  G   I  +E   SA   P
Sbjct: 677 PP--------LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 719



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 43/161 (26%), Positives = 59/161 (36%), Gaps = 14/161 (8%)

Query: 253 PRSEPAPLPAHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPR 312
           PR   +    H   +  P    RPSA      P++     + T L    R  P+    PR
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264

Query: 313 LALDPDALAGFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDPAPLHD---PT-- 367
               P      P+GL  L  P       D    L  L     AT    A L     PT  
Sbjct: 265 APAHPSQPK--PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP 322

Query: 368 SAPWATALARRVAAEL------QAAAAELRSLPGLPPATAP 402
           + P +++L  ++A  L       +A   L++LP  PPAT P
Sbjct: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS-PPATPP 362



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 73/303 (24%), Positives = 91/303 (30%), Gaps = 55/303 (18%)

Query: 125 PGGQRLVVLHLEEVTWEPTPSLRFQEP-------------PPGGAGPPELALLVLYPGPG 171
           P     + +HL +  + P PS   Q P              P    PP LA   L   P 
Sbjct: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 484

Query: 172 PEVTVTRAGLPGAQSLCPSRDTRYLVLAVDRPAGAWRGSGLALTLQPRGEDSRLSTARLQ 231
           P         P +  + PS           +         L L   P      L+T  LQ
Sbjct: 485 P---------PASPPMSPS------ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ 529

Query: 232 ALLFGDDHRCFTRMTP---------ALLLLPRSEPAPLPAHGQLDTVPFPPPRPSAELEE 282
           AL        F    P         + L  P  +  P+ A   L   P PP  P+ +   
Sbjct: 530 AL--PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 587

Query: 283 SPPSADPFLETL-TRLVRALR--VPPARASAPRLALDPDALAGFPQGLVNLSDPAALERL 339
            PP+  P       RL  AL    PP  + +P   L    LAG        S P  L   
Sbjct: 588 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT--STPEELRGY 645

Query: 340 LDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWATALARRVAAELQAAAAELRSLPGLPPA 399
             G         P       P P     +A    A +R  A  L    A    LP  PPA
Sbjct: 646 DSG---------PEGGAAASPPP-DAELAACHPAAWSRGPAPPLAFRGAPGAPLP-WPPA 694

Query: 400 TAP 402
           T P
Sbjct: 695 TGP 697


>gi|7656928 bone morphogenetic protein 10 preproprotein [Homo
           sapiens]
          Length = 424

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 4/86 (4%)

Query: 477 VLIPETYQANNCQGVCGWPQSDR-NPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKL 535
           ++ P  Y+A  C+GVC +P ++   P    H ++   +  + +  A   CCVPT      
Sbjct: 341 IIAPPGYEAYECRGVCNYPLAEHLTPT--KHAIIQALVHLKNSQKASKACCVPTKLEPIS 398

Query: 536 LISLSEERIS-AHHVPNMVATECGCR 560
           ++ L +  ++       M  +ECGCR
Sbjct: 399 ILYLDKGVVTYKFKYEGMAVSECGCR 424


>gi|157276597 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 3/85 (3%)

Query: 477 VLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLL 536
           ++ P  YQA  C G C +P +D +    NH ++   + +  +++ +  CCVPT  +   +
Sbjct: 326 IVAPPGYQAFYCHGDCPFPLAD-HLNSTNHAIVQTLVNSVNSSIPK-ACCVPTELSAISM 383

Query: 537 ISLSE-ERISAHHVPNMVATECGCR 560
           + L E +++   +   MV   CGCR
Sbjct: 384 LYLDEYDKVVLKNYQEMVVEGCGCR 408


>gi|157276595 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 3/85 (3%)

Query: 477 VLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLL 536
           ++ P  YQA  C G C +P +D +    NH ++   + +  +++ +  CCVPT  +   +
Sbjct: 326 IVAPPGYQAFYCHGDCPFPLAD-HLNSTNHAIVQTLVNSVNSSIPK-ACCVPTELSAISM 383

Query: 537 ISLSE-ERISAHHVPNMVATECGCR 560
           + L E +++   +   MV   CGCR
Sbjct: 384 LYLDEYDKVVLKNYQEMVVEGCGCR 408


>gi|157276593 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 3/85 (3%)

Query: 477 VLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLL 536
           ++ P  YQA  C G C +P +D +    NH ++   + +  +++ +  CCVPT  +   +
Sbjct: 326 IVAPPGYQAFYCHGDCPFPLAD-HLNSTNHAIVQTLVNSVNSSIPK-ACCVPTELSAISM 383

Query: 537 ISLSE-ERISAHHVPNMVATECGCR 560
           + L E +++   +   MV   CGCR
Sbjct: 384 LYLDEYDKVVLKNYQEMVVEGCGCR 408


>gi|4502425 bone morphogenetic protein 6 preproprotein [Homo
           sapiens]
          Length = 513

 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 5/102 (4%)

Query: 462 CALRELSV---DLRAERSVLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGA 518
           C   EL V   DL  +  ++ P+ Y AN C G C +P  + +    NH ++   +     
Sbjct: 412 CRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFP-LNAHMNATNHAIVQTLVHLMNP 470

Query: 519 ALARPPCCVPTAY-AGKLLISLSEERISAHHVPNMVATECGC 559
                PCC PT   A  +L       +      NMV   CGC
Sbjct: 471 EYVPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGC 512


>gi|4557369 bone morphogenetic protein 2 preproprotein [Homo
           sapiens]
          Length = 396

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 3/85 (3%)

Query: 477 VLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLL 536
           ++ P  Y A  C G C +P +D +    NH ++   + +  + + +  CCVPT  +   +
Sbjct: 314 IVAPPGYHAFYCHGECPFPLAD-HLNSTNHAIVQTLVNSVNSKIPK-ACCVPTELSAISM 371

Query: 537 ISLSE-ERISAHHVPNMVATECGCR 560
           + L E E++   +  +MV   CGCR
Sbjct: 372 LYLDENEKVVLKNYQDMVVEGCGCR 396


>gi|63025222 transforming growth factor, beta 1 [Homo sapiens]
          Length = 390

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 7/101 (6%)

Query: 462 CALRELSVDLRAE---RSVLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGA 518
           C +R+L +D R +   + +  P+ Y AN C G C +  S  + +Y   V+ L      GA
Sbjct: 293 CCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWS-LDTQYSK-VLALYNQHNPGA 350

Query: 519 ALARPPCCVPTAYAGKLLISLSEERISAHHVPNMVATECGC 559
           + A  PCCVP A     ++     +     + NM+   C C
Sbjct: 351 SAA--PCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKC 389


>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
          Length = 659

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 61/212 (28%), Positives = 71/212 (33%), Gaps = 42/212 (19%)

Query: 247 PALLLLPRSEPAPLPAHGQLDTVPFPPPRPSAELE---------------ESPPSADPFL 291
           PA L  P   P P P        P PPP    ELE               + P  A+P  
Sbjct: 15  PAPLPQPPPPPPPPPP-------PLPPPSGGPELEGDGLLLRERLAALGLDDPSPAEPGA 67

Query: 292 ETLTRLVRAL--------------RVPPARASAPRLA---LDPDALAGFPQGLV-NLSDP 333
             L     A               R PP R  AP  A   L+ D   G    L  +L + 
Sbjct: 68  PALRAPAAAAQGQARRAAELSPEERAPPGRPGAPEAAELELEEDEEEGEEAELDGDLLEE 127

Query: 334 AALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWATALARRVAAELQAAAAELRSL 393
             LE   + +   LLLL P AAT      +   +        AR  A E  AAAA    L
Sbjct: 128 EELEEAEEEDRSSLLLLSPPAATASQTQQIPGGSLGSVLLPAARFDAREAAAAAAAAGVL 187

Query: 394 PGLPPATAPLLARLLALCPGGPGGLGDPLRAL 425
            G   A   + A L      GPGG G    AL
Sbjct: 188 YGGDDAQGMMAAMLSHAY--GPGGCGAAAAAL 217


>gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]
          Length = 407

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 462 CALRELSVDLRA---ERSVLIPETYQANNCQGVC-----GWPQSDRNPRYGNHVVLLLKM 513
           C  ++  +D R       ++ P  Y  N C+G C     G P S  +  +   VV   +M
Sbjct: 303 CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASS--FHTAVVNQYRM 360

Query: 514 QARGAALARPPCCVPTAYAGKLLISLSEE-RISAHHVPNMVATECGC 559
           +          CC+PT  +   ++   +E  I    VPNM+  ECGC
Sbjct: 361 RGLNPGTVNS-CCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 51/195 (26%), Positives = 70/195 (35%), Gaps = 45/195 (23%)

Query: 246 TPALLLLPRSEPAPLPAHGQLD------TVPFPPPRP-SAELEESPPSADPFLETLTRLV 298
           TPA    P   PAP PA           T    PPRP S ++  SPP     +E + R  
Sbjct: 506 TPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMAR-- 563

Query: 299 RALRVPPARASAPRLALDPDALAG---------FPQGLVNLSDPAALERLLDGEE----- 344
           R  R  PAR + P     P  ++G          P G  +   P AL R L G       
Sbjct: 564 RTKRPAPARPTMP-----PPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPT 618

Query: 345 --------PLLLLLRPTAATTGDPAPLHDPTSAPWATALARRVAAELQAAAAE------- 389
                   P     R +  +   P+P     ++P   +L+     +L AA AE       
Sbjct: 619 VPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAI 678

Query: 390 --LRSLPGLPPATAP 402
             + + P +PP   P
Sbjct: 679 SGVPTPPAIPPQPRP 693



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 37/152 (24%), Positives = 55/152 (36%), Gaps = 11/152 (7%)

Query: 269 VPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPRLALDPDALAGFPQGLV 328
           VP P   P+     +P  A       T+      VPP R ++P++   P      P+   
Sbjct: 504 VPTPATTPAPAPAPAPAPAPALASAATKERTESEVPP-RPASPKVTRSP------PETAA 556

Query: 329 NLSDPAALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWAT--ALARRVAAELQAA 386
            + D A   +      P +   + + + +  PAP   P S    T  AL RR+      A
Sbjct: 557 PVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRA 616

Query: 387 AAELRSLPGLPPATAPLLARL--LALCPGGPG 416
                 LP  PP  A   +R    +  P  PG
Sbjct: 617 PTVPPPLPPTPPQPARRQSRRSPASPSPASPG 648


>gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]
          Length = 431

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 5/102 (4%)

Query: 462 CALRELSV---DLRAERSVLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGA 518
           C   EL V   DL  +  ++ PE Y A  C+G C +P +       NH ++   +     
Sbjct: 330 CKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYM-NATNHAIVQTLVHFINP 388

Query: 519 ALARPPCCVPTAY-AGKLLISLSEERISAHHVPNMVATECGC 559
                PCC PT   A  +L       +      NMV   CGC
Sbjct: 389 ETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGC 430


>gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo
           sapiens]
          Length = 493

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 43/146 (29%), Positives = 55/146 (37%), Gaps = 24/146 (16%)

Query: 262 AHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPRLALDPDALA 321
           A       P PPP P A      P+A+P    L  ++ A +   A A+A   A    A A
Sbjct: 59  AQSPFQAAPAPPPTPQA------PAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAA 112

Query: 322 GFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWATALARRVAA 381
                  +  D AAL++             P A     P P   P SAP A A     AA
Sbjct: 113 PPAPAAASTVDTAALKQ-------------PPA-----PPPPPPPVSAPAAEAAPPASAA 154

Query: 382 ELQAAAAELRSLPGLPPATAPLLARL 407
            + AAAA     P    A AP+ + L
Sbjct: 155 TIAAAAATAVVAPTSTVAVAPVASAL 180


>gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo
           sapiens]
          Length = 477

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 43/146 (29%), Positives = 55/146 (37%), Gaps = 24/146 (16%)

Query: 262 AHGQLDTVPFPPPRPSAELEESPPSADPFLETLTRLVRALRVPPARASAPRLALDPDALA 321
           A       P PPP P A      P+A+P    L  ++ A +   A A+A   A    A A
Sbjct: 59  AQSPFQAAPAPPPTPQA------PAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAA 112

Query: 322 GFPQGLVNLSDPAALERLLDGEEPLLLLLRPTAATTGDPAPLHDPTSAPWATALARRVAA 381
                  +  D AAL++             P A     P P   P SAP A A     AA
Sbjct: 113 PPAPAAASTVDTAALKQ-------------PPA-----PPPPPPPVSAPAAEAAPPASAA 154

Query: 382 ELQAAAAELRSLPGLPPATAPLLARL 407
            + AAAA     P    A AP+ + L
Sbjct: 155 TIAAAAATAVVAPTSTVAVAPVASAL 180


>gi|153792495 growth differentiation factor 15 [Homo sapiens]
          Length = 308

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 35/132 (26%), Positives = 50/132 (37%), Gaps = 10/132 (7%)

Query: 434 LRVEWRGRDPRGPGRAQRSAGATAADGP---CALRELSV---DLRAERSVLIPETYQANN 487
           L +  R +  RG  RA+   G     GP   C L  +     DL     VL P   Q   
Sbjct: 180 LELHLRPQAARGRRRARARNGDHCPLGPGRCCRLHTVRASLEDLGWADWVLSPREVQVTM 239

Query: 488 CQGVCGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYAGKLLISLSEERISAH 547
           C G C  P   R      H  +   +          PCCVP +Y   +LI  ++  +S  
Sbjct: 240 CIGAC--PSQFRAANM--HAQIKTSLHRLKPDTVPAPCCVPASYNPMVLIQKTDTGVSLQ 295

Query: 548 HVPNMVATECGC 559
              +++A +C C
Sbjct: 296 TYDDLLAKDCHC 307


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,554,407
Number of Sequences: 37866
Number of extensions: 1696693
Number of successful extensions: 8320
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 311
Number of HSP's that attempted gapping in prelim test: 7598
Number of HSP's gapped (non-prelim): 937
length of query: 560
length of database: 18,247,518
effective HSP length: 107
effective length of query: 453
effective length of database: 14,195,856
effective search space: 6430722768
effective search space used: 6430722768
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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