Guide to the Human Genome
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Name: CASP8 Sequence: fasta or formatted (479aa) NCBI GI: 15718706
Description:

caspase 8 isoform B precursor

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death

Other entries for this name:
alt prot [464aa] caspase 8 isoform C precursor
alt prot [538aa] caspase 8 isoform G precursor
alt prot [496aa] caspase 8 isoform A precursor
alt prot [464aa] caspase 8 isoform C precursor
alt prot [235aa] caspase 8 isoform E
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             3.1         15           1
 C cysteine            2.7         13           2
 D aspartate           7.3         35           3
 E glutamate           9.4         45           2
 F phenylalanine       4.2         20           2
 G glycine             4.6         22           1
 H histidine           1.5          7           1
 I isoleucine          7.1         34           2
 K lysine              7.1         34           2
 L leucine            11.5         55           2
 M methionine          3.1         15           1
 N asparagine          4.2         20           2
 P proline             4.2         20           1
 Q glutamine           5.4         26           1
 R arginine            5.4         26           1
 S serine              7.7         37           3
 T threonine           4.4         21           3
 V valine              3.1         15           1
 W tryptophan          0.2          1           1
 Y tyrosine            3.8         18           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   caspase 8 isoform B precursor 
CASP8                 1.000   caspase 8 isoform G precursor 
CASP8                 0.958   caspase 8 isoform C precursor 
CASP8                 0.958   caspase 8 isoform C precursor 
CASP8                 0.940   caspase 8 isoform A precursor 
CASP8                 0.380   caspase 8 isoform E 
CASP10                0.293   caspase 10 isoform a preproprotein 
CASP10                0.283   caspase 10 isoform d preproprotein 
CASP10                0.227   caspase 10 isoform b preproprotein 
CASP7                 0.145   caspase 7 isoform delta 
CASP7                 0.145   caspase 7 isoform alpha 
CASP7                 0.145   caspase 7 isoform alpha precursor 
CASP3                 0.143   caspase 3 preproprotein 
CASP3                 0.143   caspase 3 preproprotein 
CASP9                 0.121   caspase 9 isoform alpha preproprotein 
CFLAR                 0.121   CASP8 and FADD-like apoptosis regulator isoform 1 [...
CFLAR                 0.121   CASP8 and FADD-like apoptosis regulator isoform 1 [...
CASP6                 0.111   caspase 6 isoform alpha preproprotein 
CASP2                 0.100   caspase 2 isoform 1 preproprotein 
CASP6                 0.082   caspase 6 isoform beta 
CASP14                0.073   caspase 14 precursor 
CFLAR                 0.050   CASP8 and FADD-like apoptosis regulator isoform 2 [...
LOC197350             0.049   PREDICTED: hypothetical protein LOC197350 
LOC197350             0.049   PREDICTED: hypothetical protein LOC197350 
CASP7                 0.048   caspase 7 isoform beta 
CASP1                 0.043   caspase 1 isoform gamma precursor 
CASP1                 0.043   caspase 1 isoform alpha precursor 
CASP1                 0.043   caspase 1 isoform beta precursor 
CASP5                 0.036   caspase 5 isoform f precursor 
CASP5                 0.036   caspase 5 isoform b precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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