Guide to the Human Genome
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Name: CASP8 Sequence: fasta or formatted (235aa) NCBI GI: 15718712
Description:

caspase 8 isoform E

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death

Other entries for this name:
alt prot [464aa] caspase 8 isoform C precursor
alt prot [538aa] caspase 8 isoform G precursor
alt prot [496aa] caspase 8 isoform A precursor
alt prot [479aa] caspase 8 isoform B precursor
alt prot [464aa] caspase 8 isoform C precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             2.6          6           1
 C cysteine            1.3          3           1
 D aspartate           6.8         16           3
 E glutamate          11.1         26           2
 F phenylalanine       5.1         12           1
 G glycine             3.4          8           1
 H histidine           0.9          2           1
 I isoleucine          6.8         16           2
 K lysine              7.2         17           1
 L leucine            14.5         34           2
 M methionine          3.0          7           1
 N asparagine          3.8          9           1
 P proline             2.1          5           1
 Q glutamine           7.2         17           2
 R arginine            6.4         15           1
 S serine             11.1         26           3
 T threonine           2.6          6           1
 V valine              1.7          4           1
 W tryptophan          0.0          0           0
 Y tyrosine            2.6          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   caspase 8 isoform E 
CASP8                 0.828   caspase 8 isoform G precursor 
CASP8                 0.828   caspase 8 isoform B precursor 
CASP8                 0.761   caspase 8 isoform C precursor 
CASP8                 0.761   caspase 8 isoform C precursor 
CASP8                 0.722   caspase 8 isoform A precursor 
CASP10                0.146   caspase 10 isoform d preproprotein 
CASP10                0.146   caspase 10 isoform b preproprotein 
CASP10                0.146   caspase 10 isoform a preproprotein 
CFLAR                 0.109   CASP8 and FADD-like apoptosis regulator isoform 2 [...
CFLAR                 0.109   CASP8 and FADD-like apoptosis regulator isoform 1 [...
CFLAR                 0.109   CASP8 and FADD-like apoptosis regulator isoform 1 [...
FADD                  0.056   Fas-associated via death domain 
DSP                   0.039   desmoplakin isoform II 
PEA15                 0.039   phosphoprotein enriched in astrocytes 15 
TRIP11                0.030   thyroid hormone receptor interactor 11 
CDC42BPA              0.026   CDC42-binding protein kinase alpha isoform A 
MPRIP                 0.021   myosin phosphatase-Rho interacting protein isoform 2...
MPRIP                 0.021   myosin phosphatase-Rho interacting protein isoform 1...
PPL                   0.021   periplakin 
LOC400986             0.019   PREDICTED: protein immuno-reactive with anti-PTH po...
LOC400986             0.019   PREDICTED: protein immuno-reactive with anti-PTH po...
CDC42BPA              0.019   CDC42-binding protein kinase alpha isoform B 
CCDC122               0.019   coiled-coil domain containing 122 
MYH10                 0.019   myosin, heavy polypeptide 10, non-muscle 
CROCC                 0.019   ciliary rootlet coiled-coil 
DSP                   0.016   desmoplakin isoform I 
FMNL2                 0.016   formin-like 2 
KIF4B                 0.016   kinesin family member 4B 
DEDD                  0.016   death effector domain-containing protein 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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