Guide to the Human Genome
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Name: CFLAR Sequence: fasta or formatted (221aa) NCBI GI: 187608585
Description:

CASP8 and FADD-like apoptosis regulator isoform 2

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death

Other entries for this name:
alt prot [480aa] CASP8 and FADD-like apoptosis regulator isoform 1
alt prot [480aa] CASP8 and FADD-like apoptosis regulator isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0         11           2
 C cysteine            1.8          4           1
 D aspartate           9.0         20           1
 E glutamate           6.3         14           2
 F phenylalanine       2.3          5           1
 G glycine             3.6          8           1
 H histidine           2.3          5           1
 I isoleucine          5.9         13           1
 K lysine              9.0         20           1
 L leucine            15.8         35           2
 M methionine          3.6          8           1
 N asparagine          3.6          8           2
 P proline             3.2          7           2
 Q glutamine           3.2          7           1
 R arginine            6.8         15           2
 S serine              5.9         13           2
 T threonine           2.3          5           1
 V valine              7.7         17           2
 W tryptophan          0.0          0           0
 Y tyrosine            2.7          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   CASP8 and FADD-like apoptosis regulator isoform 2 [... 
CFLAR                 0.900   CASP8 and FADD-like apoptosis regulator isoform 1 [...
CFLAR                 0.900   CASP8 and FADD-like apoptosis regulator isoform 1 [...
CASP8                 0.118   caspase 8 isoform C precursor 
CASP8                 0.118   caspase 8 isoform C precursor 
CASP8                 0.115   caspase 8 isoform G precursor 
CASP8                 0.115   caspase 8 isoform E 
CASP8                 0.115   caspase 8 isoform B precursor 
CASP8                 0.078   caspase 8 isoform A precursor 
CASP10                0.078   caspase 10 isoform d preproprotein 
CASP10                0.078   caspase 10 isoform b preproprotein 
CASP10                0.078   caspase 10 isoform a preproprotein 
FADD                  0.034   Fas-associated via death domain 
C8orf80               0.017   hypothetical protein LOC389643 
TRIM36                0.012   tripartite motif-containing 36 isoform 1 
LRPPRC                0.012   leucine-rich PPR motif-containing protein 
RABGAP1               0.012   RAB GTPase activating protein 1 
KIAA0586              0.012   talpid3 protein 
RC3H2                 0.010   ring finger and CCCH-type zinc finger domains 2 iso...
RC3H2                 0.010   ring finger and CCCH-type zinc finger domains 2 iso...
HIVEP1                0.010   human immunodeficiency virus type I enhancer bindin...
C1orf172              0.007   hypothetical protein LOC126695 
IGBP1                 0.007   immunoglobulin binding protein 1 
CSNK2A2               0.007   casein kinase 2, alpha prime polypeptide 
CEP110                0.007   centrosomal protein 110kDa 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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