Search of human proteins with 156713444

Search of human proteins with 156713444

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo
sapiens]
         (190 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens]      378   e-105
gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens]      378   e-105
gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens]        378   e-105
gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens]       116   1e-26
gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens]       116   1e-26
gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens]       114   4e-26
gi|4506189 proteasome alpha 7 subunit [Homo sapiens]                  111   4e-25
gi|4506181 proteasome subunit alpha type 2 [Homo sapiens]             106   1e-23
gi|23110944 proteasome alpha 6 subunit [Homo sapiens]                  85   3e-17
gi|23110942 proteasome alpha 5 subunit [Homo sapiens]                  79   2e-15
gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens]         69   2e-12
gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens]        69   2e-12
gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens]         63   1e-10
gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens]        58   6e-09
gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]        42   2e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             40   0.002
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]            39   0.002
gi|225579095 S-phase cyclin A-associated protein in the ER isofo...    37   0.010
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]            37   0.010
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]            37   0.010
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]            37   0.010
gi|225579092 S-phase cyclin A-associated protein in the ER isofo...    37   0.010
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo...    37   0.010
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo...    37   0.010
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    37   0.010
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    37   0.010
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ...    36   0.017
gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform...    36   0.017
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           36   0.023
gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens]       36   0.023

>gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens]
          Length = 190

 Score =  378 bits (970), Expect = e-105
 Identities = 190/190 (100%), Positives = 190/190 (100%)

Query: 1   MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG 60
           MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG
Sbjct: 1   MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG 60

Query: 61  VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA 120
           VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA
Sbjct: 61  VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA 120

Query: 121 LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK 180
           LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK
Sbjct: 121 LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK 180

Query: 181 KEKEQKEKDK 190
           KEKEQKEKDK
Sbjct: 181 KEKEQKEKDK 190


>gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
          Length = 261

 Score =  378 bits (970), Expect = e-105
 Identities = 190/190 (100%), Positives = 190/190 (100%)

Query: 1   MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG 60
           MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG
Sbjct: 72  MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG 131

Query: 61  VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA 120
           VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA
Sbjct: 132 VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA 191

Query: 121 LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK 180
           LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK
Sbjct: 192 LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK 251

Query: 181 KEKEQKEKDK 190
           KEKEQKEKDK
Sbjct: 252 KEKEQKEKDK 261


>gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
          Length = 261

 Score =  378 bits (970), Expect = e-105
 Identities = 190/190 (100%), Positives = 190/190 (100%)

Query: 1   MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG 60
           MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG
Sbjct: 72  MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG 131

Query: 61  VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA 120
           VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA
Sbjct: 132 VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA 191

Query: 121 LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK 180
           LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK
Sbjct: 192 LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK 251

Query: 181 KEKEQKEKDK 190
           KEKEQKEKDK
Sbjct: 252 KEKEQKEKDK 261


>gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens]
          Length = 212

 Score =  116 bits (291), Expect = 1e-26
 Identities = 63/183 (34%), Positives = 106/183 (57%), Gaps = 7/183 (3%)

Query: 2   ACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGV 61
           A  + G+T+DA V+ N  R+  Q + L  ++P+  E +   +  +KQ YTQ  G+RPFG+
Sbjct: 34  AVGIRGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGI 93

Query: 62  SLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKS-ALA 120
           S L +G+D     +LYQ+DPSG Y  WKA  IG ++      L+++Y E  +   S A+ 
Sbjct: 94  SALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIK 153

Query: 121 LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK 180
           LAIK L   ++V +   + +E+A + R      +++   KEVE  + + E+E+ +AE++K
Sbjct: 154 LAIKAL---LEVVQSGGKNIELAIIRRNQ---PLKMFSAKEVELYVTEIEKEKEEAEKKK 207

Query: 181 KEK 183
            +K
Sbjct: 208 SKK 210


>gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens]
          Length = 250

 Score =  116 bits (290), Expect = 1e-26
 Identities = 63/179 (35%), Positives = 105/179 (58%), Gaps = 7/179 (3%)

Query: 6   AGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLY 65
           AG+T+DA V+ N  R+  Q + L  ++P+  E +   +  +KQ YTQ  G+RPFG+S L 
Sbjct: 76  AGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALI 135

Query: 66  IGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKS-ALALAIK 124
           +G+D     +LYQ+DPSG Y  WKA  IG ++      L+++Y E  +   S A+ LAIK
Sbjct: 136 VGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIKLAIK 195

Query: 125 VLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEK 183
            L   ++V +   + +E+A + R      +++   KEVE  + + E+E+ +AE++K +K
Sbjct: 196 AL---LEVVQSGGKNIELAIIRRNQ---PLKMFSAKEVELYVTEIEKEKEEAEKKKSKK 248


>gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens]
          Length = 256

 Score =  114 bits (286), Expect = 4e-26
 Identities = 62/178 (34%), Positives = 104/178 (58%), Gaps = 7/178 (3%)

Query: 7   GITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYI 66
           G+T+DA V+ N  R+  Q + L  ++P+  E +   +  +KQ YTQ  G+RPFG+S L +
Sbjct: 83  GLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIV 142

Query: 67  GWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKS-ALALAIKV 125
           G+D     +LYQ+DPSG Y  WKA  IG ++      L+++Y E  +   S A+ LAIK 
Sbjct: 143 GFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIKLAIKA 202

Query: 126 LNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEK 183
           L   ++V +   + +E+A + R      +++   KEVE  + + E+E+ +AE++K +K
Sbjct: 203 L---LEVVQSGGKNIELAIIRRNQ---PLKMFSAKEVELYVTEIEKEKEEAEKKKSKK 254


>gi|4506189 proteasome alpha 7 subunit [Homo sapiens]
          Length = 248

 Score =  111 bits (277), Expect = 4e-25
 Identities = 58/179 (32%), Positives = 105/179 (58%), Gaps = 7/179 (3%)

Query: 6   AGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLY 65
           AG+T+DA ++ N  R+  Q + L  ++P+  E +   +  +KQ YTQ  G+RPFG+S L 
Sbjct: 74  AGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALI 133

Query: 66  IGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDY-KEGEMTLKSALALAIK 124
           +G+D     +LYQ+DPSG Y  WKA  IG  + +    L+++Y  E   T    + L IK
Sbjct: 134 VGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIK 193

Query: 125 VLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEK 183
            L   ++V +   + +E+A + R+     +++L  +E+E+ + + E+E+ + E++K++K
Sbjct: 194 AL---LEVVQSGGKNIELAVMRRDQS---LKILNPEEIEKYVAEIEKEKEENEKKKQKK 246


>gi|4506181 proteasome subunit alpha type 2 [Homo sapiens]
          Length = 234

 Score =  106 bits (265), Expect = 1e-23
 Identities = 57/137 (41%), Positives = 85/137 (62%), Gaps = 3/137 (2%)

Query: 6   AGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLY 65
           +G+  D  VL +  R +AQ+Y L YQEPIP  QLV  +  + Q YTQ GG RPFGVSLL 
Sbjct: 77  SGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLI 136

Query: 66  IGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKV 125
            GW++   + L+QSDPSG Y  WKAT +G N     + L++ Y E ++ L+ A+  AI  
Sbjct: 137 CGWNEGRPY-LFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNE-DLELEDAIHTAILT 194

Query: 126 LNKTMDVSKLSAEKVEI 142
           L ++ +  +++ + +E+
Sbjct: 195 LKESFE-GQMTEDNIEV 210


>gi|23110944 proteasome alpha 6 subunit [Homo sapiens]
          Length = 246

 Score = 85.1 bits (209), Expect = 3e-17
 Identities = 50/164 (30%), Positives = 83/164 (50%), Gaps = 4/164 (2%)

Query: 1   MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG 60
           + C + G+T+D+       R  A  +  +Y   IP + L   + DI Q YTQ    RP G
Sbjct: 76  IGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLG 135

Query: 61  VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSML-KQDYKEGEMTLKSAL 119
             ++ IG D+  G Q+Y+ DP+G Y G+KAT  G     + S L K+  K+ + T +  +
Sbjct: 136 CCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTV 195

Query: 120 ALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVE 163
             AI  L+  + +      ++E+  +T EN K   R+L + E++
Sbjct: 196 ETAITCLSTVLSID-FKPSEIEVGVVTVENPK--FRILTEAEID 236


>gi|23110942 proteasome alpha 5 subunit [Homo sapiens]
          Length = 241

 Score = 79.0 bits (193), Expect = 2e-15
 Identities = 56/175 (32%), Positives = 99/175 (56%), Gaps = 17/175 (9%)

Query: 1   MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGK---- 56
           + C+++G+ +DA  L ++ R+  Q +   Y E +  E +  A+ ++     QFG +    
Sbjct: 74  IGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQFGEEDADP 130

Query: 57  ----RPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGE 112
               RPFGV+LL+ G D+  G QL+  DPSG +    A  IG+ S  A S L++ Y +  
Sbjct: 131 GAMSRPFGVALLFGGVDEK-GPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHK-S 188

Query: 113 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIK 167
           MTLK A+  ++ +L + M+  KL+A  +E+AT+  + G+    +  ++E+E++IK
Sbjct: 189 MTLKEAIKSSLIILKQVME-EKLNATNIELATV--QPGQN-FHMFTKEELEEVIK 239


>gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens]
          Length = 263

 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 54/188 (28%), Positives = 93/188 (49%), Gaps = 7/188 (3%)

Query: 4   SVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSL 63
           S+AG+T+DA +L N +R         +  P+P  +LV+ +    Q  TQ  G+RP+GV L
Sbjct: 73  SIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGL 132

Query: 64  LYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKE-GEMTLKSALALA 122
           L  G+D   G  ++Q+ PS NY   +A  IG  S +A + L++   E  E  L   +   
Sbjct: 133 LIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHG 191

Query: 123 IKVLNKTMDVSK-LSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEE-EAKAEREK 180
           ++ L +T+   + L+ + V I  + ++   T   +    +V   ++  EE  + KA+  +
Sbjct: 192 LRALRETLPAEQDLTTKNVSIGIVGKDLEFT---IYDDDDVSPFLEGLEERPQRKAQPAQ 248

Query: 181 KEKEQKEK 188
              E  EK
Sbjct: 249 PADEPAEK 256


>gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens]
          Length = 269

 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 54/188 (28%), Positives = 93/188 (49%), Gaps = 7/188 (3%)

Query: 4   SVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSL 63
           S+AG+T+DA +L N +R         +  P+P  +LV+ +    Q  TQ  G+RP+GV L
Sbjct: 79  SIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGL 138

Query: 64  LYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKE-GEMTLKSALALA 122
           L  G+D   G  ++Q+ PS NY   +A  IG  S +A + L++   E  E  L   +   
Sbjct: 139 LIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHG 197

Query: 123 IKVLNKTMDVSK-LSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEE-EAKAEREK 180
           ++ L +T+   + L+ + V I  + ++   T   +    +V   ++  EE  + KA+  +
Sbjct: 198 LRALRETLPAEQDLTTKNVSIGIVGKDLEFT---IYDDDDVSPFLEGLEERPQRKAQPAQ 254

Query: 181 KEKEQKEK 188
              E  EK
Sbjct: 255 PADEPAEK 262


>gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens]
          Length = 255

 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 52/188 (27%), Positives = 83/188 (44%), Gaps = 15/188 (7%)

Query: 4   SVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSL 63
           +VAG+ +DA  L +  R  A  +   +   IP + L   +     AYT +   RPFG S 
Sbjct: 77  AVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSF 136

Query: 64  LYIGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALA 122
           +   +  + G QLY  DPSG +YG W         AA   + K   K  EMT +  +   
Sbjct: 137 MLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--EMTCRDIVKEV 194

Query: 123 IKVLNKTMDVSKLSAEKVEIATLTR-ENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKK 181
            K++    D  K  A ++E++ +    NG+            +++ K   EEA+   ++ 
Sbjct: 195 AKIIYIVHDEVKDKAFELELSWVGELTNGR-----------HEIVPKDIREEAEKYAKES 243

Query: 182 EKEQKEKD 189
            KE+ E D
Sbjct: 244 LKEEDESD 251


>gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens]
          Length = 248

 Score = 57.8 bits (138), Expect = 6e-09
 Identities = 52/188 (27%), Positives = 82/188 (43%), Gaps = 22/188 (11%)

Query: 4   SVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSL 63
           +VAG+ +DA  L +  R  A  +   +   IP + L   +     AYT +   RPFG S+
Sbjct: 77  AVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSV 136

Query: 64  LYIGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALA 122
                  + G QLY  DPSG +YG W         AA   + K   K  EMT +  +   
Sbjct: 137 -------NDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--EMTCRDIVKEV 187

Query: 123 IKVLNKTMDVSKLSAEKVEIATLTR-ENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKK 181
            K++    D  K  A ++E++ +    NG+            +++ K   EEA+   ++ 
Sbjct: 188 AKIIYIVHDEVKDKAFELELSWVGELTNGR-----------HEIVPKDIREEAEKYAKES 236

Query: 182 EKEQKEKD 189
            KE+ E D
Sbjct: 237 LKEEDESD 244


>gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]
          Length = 273

 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 7/149 (4%)

Query: 3   CSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVS 62
           C  AG+ +DA + T   R++A +  L         ++ T    ++Q   ++ G    G S
Sbjct: 82  CCGAGVAADAEMTT---RMVASKMELHALSTGREPRVATVTRILRQTLFRYQGH--VGAS 136

Query: 63  LLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALA 122
           L+  G D   G QLY   P G+Y     T +G+   AA+++L +D  +  MTL++A  L 
Sbjct: 137 LIVGGVDLT-GPQLYGVHPHGSYSRLPFTALGSGQDAALAVL-EDRFQPNMTLEAAQGLL 194

Query: 123 IKVLNKTMDVSKLSAEKVEIATLTRENGK 151
           ++ +   +     S   V+   +T+   K
Sbjct: 195 VEAVTAGILGDLGSGGNVDACVITKTGAK 223


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 13/97 (13%)

Query: 98  AAAVSMLKQDYKEGEMTL----KSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTV 153
           +AAV   ++  +E E  +    K+A A  +K L++ + + +      EI    RE     
Sbjct: 456 SAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERERE----- 510

Query: 154 IRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
               K++E E+ ++K +E+E + EREK  + Q+EK+K
Sbjct: 511 ----KEREREKELEKEQEQEREKEREKDRERQQEKEK 543



 Score = 31.6 bits (70), Expect = 0.43
 Identities = 15/33 (45%), Positives = 23/33 (69%)

Query: 158 KQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
           K+ E EQ  ++  E+E K E+EK+ + QKEK+K
Sbjct: 543 KELEKEQEKQREMEKERKQEKEKELERQKEKEK 575



 Score = 29.6 bits (65), Expect = 1.6
 Identities = 12/33 (36%), Positives = 26/33 (78%)

Query: 158 KQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
           KQ+E+E+  K+ +E+E + ++EK+++ QK K++
Sbjct: 551 KQREMEKERKQEKEKELERQKEKEKELQKMKEQ 583



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 12/31 (38%), Positives = 23/31 (74%)

Query: 158 KQKEVEQLIKKHEEEEAKAEREKKEKEQKEK 188
           +QKE E+ ++K +E+E + E EK+ ++ +EK
Sbjct: 569 RQKEKEKELQKMKEQEKECELEKEREKLEEK 599



 Score = 27.3 bits (59), Expect = 8.1
 Identities = 14/59 (23%), Positives = 32/59 (54%)

Query: 128 KTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQK 186
           K  ++ K   ++ E+    ++  +  +   K+KE E    K +E+E + E+E+++ E+K
Sbjct: 541 KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEK 599



 Score = 27.3 bits (59), Expect = 8.1
 Identities = 12/33 (36%), Positives = 24/33 (72%)

Query: 158 KQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
           K+KE+E+  +K +E +   E+EK+ + +KE++K
Sbjct: 563 KEKELERQKEKEKELQKMKEQEKECELEKEREK 595


>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 1/89 (1%)

Query: 102 SMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKE 161
           S  K+  K+     K      +K   KT    K + +  +  T T++   T  +  K+KE
Sbjct: 21  SAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKE-KEKE 79

Query: 162 VEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
            E+  +K +E+E + E+EKK+K++K+K K
Sbjct: 80  KEKEKEKEKEKEKEKEKEKKKKKKKKKKK 108



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 5/82 (6%)

Query: 109 KEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKK 168
           K+ + T+K       K    T    + +  K    T T+E  K      K+KE E+  +K
Sbjct: 36  KKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKE-----KEKEKEKEKEK 90

Query: 169 HEEEEAKAEREKKEKEQKEKDK 190
            +E+E + +++KK+K++K+K K
Sbjct: 91  EKEKEKEKKKKKKKKKKKKKKK 112


>gi|225579095 S-phase cyclin A-associated protein in the ER isoform
           b [Homo sapiens]
          Length = 1154

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 17/64 (26%), Positives = 36/64 (56%)

Query: 126 LNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQ 185
           LN+  +  +   E+ +      +  K  +   +Q  VE+L+ K +E+EA+ E++++EKE+
Sbjct: 406 LNELQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEK 465

Query: 186 KEKD 189
             +D
Sbjct: 466 ARED 469


>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 6/103 (5%)

Query: 88  WKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKT----MDVSKLSAEKVEIA 143
           WK  C+    A   + +K + +     +++A    I++LN+T     ++S   A+  ++ 
Sbjct: 457 WKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLT 516

Query: 144 TLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQK 186
           T  +E  K  +   K+K + + + K+EE   K  +  KEKE++
Sbjct: 517 TELKEEEKAFVN--KEKMLMKELSKYEEIFVKETQINKEKEEE 557


>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 6/103 (5%)

Query: 88  WKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKT----MDVSKLSAEKVEIA 143
           WK  C+    A   + +K + +     +++A    I++LN+T     ++S   A+  ++ 
Sbjct: 457 WKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLT 516

Query: 144 TLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQK 186
           T  +E  K  +   K+K + + + K+EE   K  +  KEKE++
Sbjct: 517 TELKEEEKAFVN--KEKMLMKELSKYEEIFVKETQINKEKEEE 557


>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 6/103 (5%)

Query: 88  WKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKT----MDVSKLSAEKVEIA 143
           WK  C+    A   + +K + +     +++A    I++LN+T     ++S   A+  ++ 
Sbjct: 457 WKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLT 516

Query: 144 TLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQK 186
           T  +E  K  +   K+K + + + K+EE   K  +  KEKE++
Sbjct: 517 TELKEEEKAFVN--KEKMLMKELSKYEEIFVKETQINKEKEEE 557


>gi|225579092 S-phase cyclin A-associated protein in the ER isoform
           a [Homo sapiens]
          Length = 1400

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 17/64 (26%), Positives = 36/64 (56%)

Query: 126 LNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQ 185
           LN+  +  +   E+ +      +  K  +   +Q  VE+L+ K +E+EA+ E++++EKE+
Sbjct: 652 LNELQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEK 711

Query: 186 KEKD 189
             +D
Sbjct: 712 ARED 715


>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 23/60 (38%), Positives = 37/60 (61%), Gaps = 2/60 (3%)

Query: 131 DVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
           D  KL+A+K    +   E+ K  +   K+K+ ++  KK +EE+ KAE E K+KE++EK K
Sbjct: 39  DDIKLTAKKE--VSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKK 96



 Score = 35.0 bits (79), Expect = 0.039
 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 92  CIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGK 151
           C    + ++    K D K   +T K  ++ A +   K ++  K   E  E      E  K
Sbjct: 25  CSERRTVSSKERPKDDIK---LTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVK 81

Query: 152 TVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEK 188
                 K++E E+  KKH+EEE K + E+ +++Q+E+
Sbjct: 82  AEEESKKKEEEEK--KKHQEEERKKQEEQAKRQQEEE 116



 Score = 29.6 bits (65), Expect = 1.6
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 126 LNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKE---VEQLIKKHEEEEAKAEREKKE 182
           L    +VSK   +K +     +   +   R  K +E    E+  KK EEEE K  +E++ 
Sbjct: 43  LTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER 102

Query: 183 KEQKEKDK 190
           K+Q+E+ K
Sbjct: 103 KKQEEQAK 110



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 13/45 (28%), Positives = 29/45 (64%)

Query: 146 TRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
           ++E  K  I++  +KEV +  +  ++     +R+K++KE+K+KD+
Sbjct: 33  SKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDE 77


>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 23/60 (38%), Positives = 37/60 (61%), Gaps = 2/60 (3%)

Query: 131 DVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
           D  KL+A+K    +   E+ K  +   K+K+ ++  KK +EE+ KAE E K+KE++EK K
Sbjct: 39  DDIKLTAKKE--VSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKK 96



 Score = 35.0 bits (79), Expect = 0.039
 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 92  CIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGK 151
           C    + ++    K D K   +T K  ++ A +   K ++  K   E  E      E  K
Sbjct: 25  CSERRTVSSKERPKDDIK---LTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVK 81

Query: 152 TVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEK 188
                 K++E E+  KKH+EEE K + E+ +++Q+E+
Sbjct: 82  AEEESKKKEEEEK--KKHQEEERKKQEEQAKRQQEEE 116



 Score = 29.6 bits (65), Expect = 1.6
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 126 LNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKE---VEQLIKKHEEEEAKAEREKKE 182
           L    +VSK   +K +     +   +   R  K +E    E+  KK EEEE K  +E++ 
Sbjct: 43  LTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER 102

Query: 183 KEQKEKDK 190
           K+Q+E+ K
Sbjct: 103 KKQEEQAK 110



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 13/45 (28%), Positives = 29/45 (64%)

Query: 146 TRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
           ++E  K  I++  +KEV +  +  ++     +R+K++KE+K+KD+
Sbjct: 33  SKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDE 77


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
           b [Homo sapiens]
          Length = 1524

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 15/105 (14%)

Query: 101 VSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQK 160
           + + ++D    + TL S  + A K  +K +   ++ +   E A L RE    +    K+K
Sbjct: 283 IHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEK 342

Query: 161 E--------------VEQLIKKHEEEEAKAEREK-KEKEQKEKDK 190
           E               E+L KK E+E  K EREK +EK ++EK K
Sbjct: 343 EDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRK 387


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
           a [Homo sapiens]
          Length = 1556

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 15/105 (14%)

Query: 101 VSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQK 160
           + + ++D    + TL S  + A K  +K +   ++ +   E A L RE    +    K+K
Sbjct: 283 IHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEK 342

Query: 161 E--------------VEQLIKKHEEEEAKAEREK-KEKEQKEKDK 190
           E               E+L KK E+E  K EREK +EK ++EK K
Sbjct: 343 EDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRK 387


>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
           [Homo sapiens]
          Length = 621

 Score = 36.2 bits (82), Expect = 0.017
 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 1/68 (1%)

Query: 123 IKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKE 182
           I+  N+     +   E   I TL         R+ K KE E+  KK  E++AKAE ++KE
Sbjct: 247 IEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE-EEKAKKEAEKKAKAEAKRKE 305

Query: 183 KEQKEKDK 190
           +E KEK +
Sbjct: 306 QEAKEKQR 313



 Score = 28.5 bits (62), Expect = 3.6
 Identities = 15/63 (23%), Positives = 32/63 (50%)

Query: 123 IKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKE 182
           ++ L   ++++ L      + + T+E GK  +    ++  EQ+ K+ EE EA+  +  K 
Sbjct: 380 VEKLCDRLELASLQCLNETLTSCTKEVGKAALEKQIEEINEQIRKEKEEAEARMRQASKN 439

Query: 183 KEQ 185
            E+
Sbjct: 440 TEK 442


>gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 2
           [Homo sapiens]
          Length = 568

 Score = 36.2 bits (82), Expect = 0.017
 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 1/68 (1%)

Query: 123 IKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKE 182
           I+  N+     +   E   I TL         R+ K KE E+  KK  E++AKAE ++KE
Sbjct: 247 IEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE-EEKAKKEAEKKAKAEAKRKE 305

Query: 183 KEQKEKDK 190
           +E KEK +
Sbjct: 306 QEAKEKQR 313


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 35.8 bits (81), Expect = 0.023
 Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 5/96 (5%)

Query: 100 AVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKT----VIR 155
           AVS L +  +  E   K A +   K L KT   +K S+EK        E  KT     ++
Sbjct: 330 AVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALK 389

Query: 156 VLKQKEVEQLI-KKHEEEEAKAEREKKEKEQKEKDK 190
             K+K ++  + KKH +E+     EKK+KE+KE  K
Sbjct: 390 AEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKK 425


>gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens]
          Length = 822

 Score = 35.8 bits (81), Expect = 0.023
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 11/97 (11%)

Query: 105 KQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLT---------RENGKTVIR 155
           ++DY+E  +T+K+ L L   V  K     ++    +E   LT          E G  +I 
Sbjct: 271 EEDYREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPDVEEGGSAIIF 330

Query: 156 VLK--QKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
             K  Q+ +E +I   EEEE   +++KK+++Q +K K
Sbjct: 331 SDKTIQQVIEDIIANQEEEEKNKKKKKKKEKQPKKAK 367



 Score = 27.7 bits (60), Expect = 6.2
 Identities = 12/52 (23%), Positives = 34/52 (65%), Gaps = 1/52 (1%)

Query: 139 KVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 190
           ++++  L R+  K  +++   +E E+ +K  ++++ K ++ KK++++ +KDK
Sbjct: 437 RIQVDELMRQELKN-LKLAVDRERERPVKAGKKKDKKGKKGKKKEKKAKKDK 487


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,617,880
Number of Sequences: 37866
Number of extensions: 286501
Number of successful extensions: 7533
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 291
Number of HSP's successfully gapped in prelim test: 189
Number of HSP's that attempted gapping in prelim test: 3887
Number of HSP's gapped (non-prelim): 2829
length of query: 190
length of database: 18,247,518
effective HSP length: 96
effective length of query: 94
effective length of database: 14,612,382
effective search space: 1373563908
effective search space used: 1373563908
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.